39122:KV203 RS07060
gene id: 39122:KV203_RS07060
uniprot id: A0A8F6HQL9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

39122:KV203 RS04085
gene id: 39122:KV203_RS04085
uniprot id: A0A8F6DXQ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

39122:KV203 RS04395
gene id: 39122:KV203_RS04395
uniprot id: A0A8F6HPK7
names: Subcellular Location Annotation
messages: Membrane

39122:KV203 RS04045
gene id: 39122:KV203_RS04045
uniprot id: A0A8F6E2F3
names: Subcellular Location Annotation
messages: Membrane

39122:KV203 RS17705
gene id: 39122:KV203_RS17705
uniprot id: A0A8F6DVW0
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

39122:KV203 RS09565
gene id: 39122:KV203_RS09565
uniprot id: A0A8F6DZG1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

39122:KV203 RS04535
gene id: 39122:KV203_RS04535
uniprot id: A0A8F6E2L2
names: Similarity
messages: Belongs to the FBPase class 2 family.

39122:KV203 RS05760
gene id: 39122:KV203_RS05760
uniprot id: A0A8F6HNY3
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

39122:KV203 RS13280
gene id: 39122:KV203_RS13280
uniprot id: A0A8F6DUK5
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

39122:KV203 RS16905
gene id: 39122:KV203_RS16905
uniprot id: A0A8F6HQG5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

39122:KV203 RS01370
gene id: 39122:KV203_RS01370
uniprot id: A0A8F6DW81
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon.

39122:KV203 RS16975
gene id: 39122:KV203_RS16975
uniprot id: A0A8F6HMM4
names: Similarity
messages: Belongs to the GARS family.

39122:KV203 RS11995
gene id: 39122:KV203_RS11995
uniprot id: A0A8F6DTL6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

39122:KV203 RS05060
gene id: 39122:KV203_RS05060
uniprot id: A0A8F6E054
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

39122:KV203 RS04450
gene id: 39122:KV203_RS04450
uniprot id: A0A8F6DY73
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

39122:KV203 RS19115
gene id: 39122:KV203_RS19115
uniprot id: A0A8F6HMZ5
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

39122:KV203 RS17955
gene id: 39122:KV203_RS17955
uniprot id: A0A8F6HNN5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.

39122:KV203 RS15540
gene id: 39122:KV203_RS15540
uniprot id: A0A8F6HP04
names: Cofactor
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 1 family.
messages: Binds 1 zinc ion per subunit.

39122:KV203 RS03710
gene id: 39122:KV203_RS03710
uniprot id: A0A8F6E2B0
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

39122:KV203 RS05935
gene id: 39122:KV203_RS05935
uniprot id: A0A8F6E0E1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

39122:KV203 RS03530
gene id: 39122:KV203_RS03530
uniprot id: A0A8F6DXI1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

39122:KV203 RS11330
gene id: 39122:KV203_RS11330
uniprot id: A0A8F6HND0
names: Subcellular Location Annotation
messages: Membrane

39122:KV203 RS03555
gene id: 39122:KV203_RS03555
uniprot id: A0A8F6E293
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

39122:KV203 RS06855
gene id: 39122:KV203_RS06855
uniprot id: A0A8F6DYX8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

39122:KV203 RS09520
gene id: 39122:KV203_RS09520
uniprot id: A0A8F6HPH7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

39122:KV203 RS03240
gene id: 39122:KV203_RS03240
uniprot id: A0A8F6DXF2
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

39122:KV203 RS10435
gene id: 39122:KV203_RS10435
uniprot id: A0A8F6HLJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

39122:KV203 RS05780
gene id: 39122:KV203_RS05780
uniprot id: A0A8F6HPU6
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

39122:KV203 RS15305
gene id: 39122:KV203_RS15305
uniprot id: A0A8F6DWC4
names: Similarity
messages: Belongs to the FPG family.

39122:KV203 RS13620
gene id: 39122:KV203_RS13620
uniprot id: A0A8F6DUR1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

39122:KV203 RS10270
gene id: 39122:KV203_RS10270
uniprot id: A0A8F6HMG8
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

39122:KV203 RS00560
gene id: 39122:KV203_RS00560
uniprot id: A0A8F6DWX4
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.
messages: Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.

39122:KV203 RS12705
gene id: 39122:KV203_RS12705
uniprot id: A0A8F6HNK4
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

39122:KV203 RS09735
gene id: 39122:KV203_RS09735
uniprot id: A0A8F6DZF7
names: Similarity
names: Subunit
messages: Belongs to the AAA ATPase family.
messages: Homohexamer. Assembles into a hexameric ring structure.

39122:KV203 RS18005
gene id: 39122:KV203_RS18005
uniprot id: A0A8F6DX50
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

39122:KV203 RS18500
gene id: 39122:KV203_RS18500
uniprot id: A0A8F6HQ80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

39122:KV203 RS07365
gene id: 39122:KV203_RS07365
uniprot id: A0A8F6E3P7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

39122:KV203 RS17840
gene id: 39122:KV203_RS17840
uniprot id: A0A8F6HMU4
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

39122:KV203 RS03835
gene id: 39122:KV203_RS03835
uniprot id: A0A8F6DXM8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

39122:KV203 RS02305
gene id: 39122:KV203_RS02305
uniprot id: A0A8F6HNE2
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

39122:KV203 RS09610
gene id: 39122:KV203_RS09610
uniprot id: A0A8F6HPN4
names: Similarity
messages: Belongs to the CobH/CbiC family.

39122:KV203 RS18755
gene id: 39122:KV203_RS18755
uniprot id: A0A8F6HMX3
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

39122:KV203 RS12740
gene id: 39122:KV203_RS12740
uniprot id: A0A8F6DUC7
names: Similarity
messages: Belongs to the EspG family.

39122:KV203 RS03380
gene id: 39122:KV203_RS03380
uniprot id: A0A8F6HRI2
names: Similarity
messages: Belongs to the UPF0234 family.

39122:KV203 RS14115
gene id: 39122:KV203_RS14115
uniprot id: A0A8F6HN41
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

39122:KV203 RS06305
gene id: 39122:KV203_RS06305
uniprot id: A0A8F6DZJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

39122:KV203 RS16225
gene id: 39122:KV203_RS16225
uniprot id: A0A8F6E4U2
names: Similarity
messages: Belongs to the citrate synthase family.

39122:KV203 RS08380
gene id: 39122:KV203_RS08380
uniprot id: A0A8F6E3H1
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

39122:KV203 RS01380
gene id: 39122:KV203_RS01380
uniprot id: A0A8F6DWV1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterioferritin family.
messages: Homooligomer of 24 subunits, arranged as 12 dimers, that are packed together to form an approximately spherical molecule with a central cavity, in which large amounts of iron can be deposited.
messages: Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.

39122:KV203 RS10790
gene id: 39122:KV203_RS10790
uniprot id: A0A8F6E244
names: Similarity
messages: Belongs to the cytochrome P450 family.

39122:KV203 RS18560
gene id: 39122:KV203_RS18560
uniprot id: A0A8F6E0T3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.
messages: Cytoplasm
messages: Monomer.

39122:KV203 RS09245
gene id: 39122:KV203_RS09245
uniprot id: A0A8F6HQY0
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

39122:KV203 RS12045
gene id: 39122:KV203_RS12045
uniprot id: A0A8F6HLT5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

39122:KV203 RS08615
gene id: 39122:KV203_RS08615
uniprot id: A0A8F6HQU9
names: Similarity
messages: Belongs to the TfdA dioxygenase family.

39122:KV203 RS18940
gene id: 39122:KV203_RS18940
uniprot id: A0A8F6HPH3
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

39122:KV203 RS15910
gene id: 39122:KV203_RS15910
uniprot id: A0A8F6DZQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Membrane

39122:KV203 RS06835
gene id: 39122:KV203_RS06835
uniprot id: A0A8F6E3I6
names: Similarity
messages: Belongs to the peptidase C40 family.

39122:KV203 RS14385
gene id: 39122:KV203_RS14385
uniprot id: A0A8F6HNU5
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

39122:KV203 RS03455
gene id: 39122:KV203_RS03455
uniprot id: A0A8F6DZP1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

39122:KV203 RS13735
gene id: 39122:KV203_RS13735
uniprot id: A0A8F6HM88
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

39122:KV203 RS18470
gene id: 39122:KV203_RS18470
uniprot id: A0A8F6HMV8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

39122:KV203 RS04370
gene id: 39122:KV203_RS04370
uniprot id: A0A8F6DY60
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

39122:KV203 RS15370
gene id: 39122:KV203_RS15370
uniprot id: A0A8F6DUL9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

39122:KV203 RS10545
gene id: 39122:KV203_RS10545
uniprot id: A0A8F6DTP4
names: Caution
names: Similarity
messages: Belongs to the NTE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

39122:KV203 RS01775
gene id: 39122:KV203_RS01775
uniprot id: A0A8F6DZ28
names: Similarity
messages: Belongs to the Nudix hydrolase family. PCD1 subfamily.

39122:KV203 RS06175
gene id: 39122:KV203_RS06175
uniprot id: A0A8F6DXS0
names: Subcellular Location Annotation
messages: Membrane

39122:KV203 RS07465
gene id: 39122:KV203_RS07465
uniprot id: A0A8F6E0W1
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.

39122:KV203 RS07470
gene id: 39122:KV203_RS07470
uniprot id: A0A8F6E3I4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

39122:KV203 RS11780
gene id: 39122:KV203_RS11780
uniprot id: A0A8F6HLX4
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

39122:KV203 RS04015
gene id: 39122:KV203_RS04015
uniprot id: A0A8F6DX32
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

39122:KV203 RS02240
gene id: 39122:KV203_RS02240
uniprot id: A0A8F6HSM7
names: Subcellular Location Annotation
messages: Membrane

39122:KV203 RS14365
gene id: 39122:KV203_RS14365
uniprot id: A0A8F6HMB9
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

39122:KV203 RS10190
gene id: 39122:KV203_RS10190
uniprot id: A0A8F6HMG3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the insertion of ferrous iron into coproporphyrin III to form Fe-coproporphyrin III.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

39122:KV203 RS02870
gene id: 39122:KV203_RS02870
uniprot id: A0A8F6HPB6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

39122:KV203 RS16830
gene id: 39122:KV203_RS16830
uniprot id: A0A8F6DVL8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

39122:KV203 RS03775
gene id: 39122:KV203_RS03775
uniprot id: A0A8F6DXL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

39122:KV203 RS15945
gene id: 39122:KV203_RS15945
uniprot id: A0A8F6DXE5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

39122:KV203 RS17885
gene id: 39122:KV203_RS17885
uniprot id: A0A8F6E5F6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

39122:KV203 RS17745
gene id: 39122:KV203_RS17745
uniprot id: A0A8F6DY03
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

39122:KV203 RS02260
gene id: 39122:KV203_RS02260
uniprot id: A0A8F6DX35
names: Subcellular Location Annotation
messages: Membrane

39122:KV203 RS06375
gene id: 39122:KV203_RS06375
uniprot id: A0A8F6DYE5
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

39122:KV203 RS11870
gene id: 39122:KV203_RS11870
uniprot id: A0A8F6HLX9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

39122:KV203 RS17750
gene id: 39122:KV203_RS17750
uniprot id: A0A8F6E0J2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DisA family.
messages: Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP likely acts as a signaling molecule that may couple DNA integrity with a cellular process.
messages: Homooctamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Participates in a DNA-damage check-point. DisA forms globular foci that rapidly scan along the chromosomes searching for lesions.

39122:KV203 RS14055
gene id: 39122:KV203_RS14055
uniprot id: A0A8F6DUT1
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

39122:KV203 RS15195
gene id: 39122:KV203_RS15195
uniprot id: A0A8F6HN96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

39122:KV203 RS05335
gene id: 39122:KV203_RS05335
uniprot id: A0A8F6E315
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

39122:KV203 RS16250
gene id: 39122:KV203_RS16250
uniprot id: A0A8F6E030
names: Similarity
messages: Belongs to the citrate synthase family.

39122:KV203 RS10440
gene id: 39122:KV203_RS10440
uniprot id: A0A8F6HN85
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

39122:KV203 RS10490
gene id: 39122:KV203_RS10490
uniprot id: A0A8F6DVI8
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

39122:KV203 RS18140
gene id: 39122:KV203_RS18140
uniprot id: A0A8F6HQP4
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

39122:KV203 RS08835
gene id: 39122:KV203_RS08835
uniprot id: A0A8F6E3Y6
names: Similarity
messages: Belongs to the complex I 75 kDa subunit family.

39122:KV203 RS08810
gene id: 39122:KV203_RS08810
uniprot id: A0A8F6DZ80
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

39122:KV203 RS00820
gene id: 39122:KV203_RS00820
uniprot id: A0A8F6DX03
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

39122:KV203 RS02660
gene id: 39122:KV203_RS02660
uniprot id: A0A8F6DYE4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

39122:KV203 RS07565
gene id: 39122:KV203_RS07565
uniprot id: A0A8F6E0X1
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

39122:KV203 RS12840
gene id: 39122:KV203_RS12840
uniprot id: A0A8F6DVK7
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

39122:KV203 RS06920
gene id: 39122:KV203_RS06920
uniprot id: A0A8F6E0P7
names: Similarity
messages: Belongs to the carotenoid/retinoid oxidoreductase family.

39122:KV203 RS16705
gene id: 39122:KV203_RS16705
uniprot id: A0A8F6HMN5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PstS family.
messages: Part of the ABC transporter complex PstSACB involved in phosphate import.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

39122:KV203 RS16785
gene id: 39122:KV203_RS16785
uniprot id: A0A8F6DXM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

39122:KV203 RS09070
gene id: 39122:KV203_RS09070
uniprot id: A0A8F6HQ98
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

39122:KV203 RS07305
gene id: 39122:KV203_RS07305
uniprot id: A0A8F6HP65
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

39122:KV203 RS06980
gene id: 39122:KV203_RS06980
uniprot id: A0A8F6HPY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

39122:KV203 RS09185
gene id: 39122:KV203_RS09185
uniprot id: A0A8F6DZB8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

39122:KV203 RS00140
gene id: 39122:KV203_RS00140
uniprot id: A0A8F6DWG0
names: Similarity
messages: Belongs to the FAD-binding monooxygenase family.

39122:KV203 RS02705
gene id: 39122:KV203_RS02705
uniprot id: A0A8F6HPA7
names: Subcellular Location Annotation
messages: Membrane

39122:KV203 RS01300
gene id: 39122:KV203_RS01300
uniprot id: A0A8F6DZM5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

39122:KV203 RS05025
gene id: 39122:KV203_RS05025
uniprot id: A0A8F6DY11
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

39122:KV203 RS14470
gene id: 39122:KV203_RS14470
uniprot id: A0A8F6HM85
names: Function
names: Similarity
messages: Belongs to the EgtB family.
messages: Catalyzes the oxidative sulfurization of hercynine (N-alpha,N-alpha,N-alpha-trimethyl-L-histidine) into hercynyl-gamma-L-glutamyl-L-cysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine.

39122:KV203 RS02975
gene id: 39122:KV203_RS02975
uniprot id: A0A8F6E4N1
names: Similarity
messages: Belongs to the DNA photolyase family.

39122:KV203 RS12800
gene id: 39122:KV203_RS12800
uniprot id: A0A8F6HMW2
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

39122:KV203 RS18450
gene id: 39122:KV203_RS18450
uniprot id: A0A8F6E0S4
names: Similarity
messages: Belongs to the pirin family.

39122:KV203 RS01350
gene id: 39122:KV203_RS01350
uniprot id: A0A8F6E4J8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

39122:KV203 RS00845
gene id: 39122:KV203_RS00845
uniprot id: A0A8F6HR31
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

39122:KV203 RS09340
gene id: 39122:KV203_RS09340
uniprot id: A0A8F6HQY5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

39122:KV203 RS17130
gene id: 39122:KV203_RS17130
uniprot id: A0A8F6E0C5
names: Similarity
messages: Belongs to the HipA Ser/Thr kinase family.

39122:KV203 RS16260
gene id: 39122:KV203_RS16260
uniprot id: A0A8F6HML8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

39122:KV203 RS07370
gene id: 39122:KV203_RS07370
uniprot id: A0A8F6DZV8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

39122:KV203 RS15060
gene id: 39122:KV203_RS15060
uniprot id: A0A8F6DZP0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Belongs to the precorrin methyltransferase family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

39122:KV203 RS02440
gene id: 39122:KV203_RS02440
uniprot id: A0A8F6DZ01
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

39122:KV203 RS15520
gene id: 39122:KV203_RS15520
uniprot id: A0A8F6DVH7
names: Function
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Involved in the hydrocarbon hydroxylating system, which transfers electrons from NADH to rubredoxin reductase and then through rubredoxin to alkane 1 monooxygenase.

39122:KV203 RS16815
gene id: 39122:KV203_RS16815
uniprot id: A0A8F6HQG0
names: Similarity
messages: Belongs to the cytochrome P450 family.

39122:KV203 RS11735
gene id: 39122:KV203_RS11735
uniprot id: A0A8F6DTJ1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DtxR/MntR family.
messages: Cytoplasm
messages: Homodimer.

39122:KV203 RS16700
gene id: 39122:KV203_RS16700
uniprot id: A0A8F6DVU0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

39122:KV203 RS16075
gene id: 39122:KV203_RS16075
uniprot id: A0A8F6E522
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Homodimer.

39122:KV203 RS03900
gene id: 39122:KV203_RS03900
uniprot id: A0A8F6HPH9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

39122:KV203 RS05090
gene id: 39122:KV203_RS05090
uniprot id: A0A8F6DZP8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NucS endonuclease family.
messages: Cleaves both 3' and 5' ssDNA extremities of branched DNA structures.
messages: Cytoplasm

39122:KV203 RS09570
gene id: 39122:KV203_RS09570
uniprot id: A0A8F6DZD0
names: Similarity
messages: Belongs to the long-chain O-acyltransferase family.

39122:KV203 RS05925
gene id: 39122:KV203_RS05925
uniprot id: A0A8F6DZG2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

39122:KV203 RS04890
gene id: 39122:KV203_RS04890
uniprot id: A0A8F6HQA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

39122:KV203 RS16010
gene id: 39122:KV203_RS16010
uniprot id: A0A8F6E1H9
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

39122:KV203 RS10330
gene id: 39122:KV203_RS10330
uniprot id: A0A8F6DTQ6
names: Subcellular Location Annotation
messages: Membrane

39122:KV203 RS01855
gene id: 39122:KV203_RS01855
uniprot id: A0A8F6E1W3
names: Subcellular Location Annotation
messages: Cytoplasm

39122:KV203 RS13465
gene id: 39122:KV203_RS13465
uniprot id: A0A8F6DVS3
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

39122:KV203 RS13105
gene id: 39122:KV203_RS13105
uniprot id: A0A8F6DZB4
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

39122:KV203 RS04175
gene id: 39122:KV203_RS04175
uniprot id: A0A8F6DX52
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

39122:KV203 RS04830
gene id: 39122:KV203_RS04830
uniprot id: A0A8F6DXZ2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

39122:KV203 RS08745
gene id: 39122:KV203_RS08745
uniprot id: A0A8F6E1A9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

39122:KV203 RS12115
gene id: 39122:KV203_RS12115
uniprot id: A0A8F6DW40
names: Similarity
messages: Belongs to the UPF0102 family.

39122:KV203 RS07590
gene id: 39122:KV203_RS07590
uniprot id: A0A8F6HPB9
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

39122:KV203 RS12105
gene id: 39122:KV203_RS12105
uniprot id: A0A8F6DVB6
names: Similarity
messages: Belongs to the DprA/Smf family.

39122:KV203 RS07570
gene id: 39122:KV203_RS07570
uniprot id: A0A8F6E3J4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DtxR/MntR family.
messages: Cytoplasm
messages: Homodimer.

39122:KV203 RS03865
gene id: 39122:KV203_RS03865
uniprot id: A0A8F6DZT5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

39122:KV203 RS12685
gene id: 39122:KV203_RS12685
uniprot id: A0A8F6DYU3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
messages: Tetramer of two alpha and two beta subunits.

39122:KV203 RS00940
gene id: 39122:KV203_RS00940
uniprot id: A0A8F6HN65
names: Similarity
messages: Belongs to the AccD/PCCB family.

39122:KV203 RS13370
gene id: 39122:KV203_RS13370
uniprot id: A0A8F6DUL6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.
messages: Resistance to Hg(2+) in bacteria appears to be governed by a specialized system which includes mercuric reductase. MerA protein is responsible for volatilizing mercury as Hg(0).

39122:KV203 RS13660
gene id: 39122:KV203_RS13660
uniprot id: A0A8F6HM84
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: Could possibly oxidize fatty acids using specific components.

39122:KV203 RS04020
gene id: 39122:KV203_RS04020
uniprot id: A0A8F6DXQ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

39122:KV203 RS10615
gene id: 39122:KV203_RS10615
uniprot id: A0A8F6DXX2
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

39122:KV203 RS15255
gene id: 39122:KV203_RS15255
uniprot id: A0A8F6HMD1
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

39122:KV203 RS13495
gene id: 39122:KV203_RS13495
uniprot id: A0A8F6HM28
names: Cofactor
names: Similarity
messages: Belongs to the monomeric-type IDH family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

39122:KV203 RS03910
gene id: 39122:KV203_RS03910
uniprot id: A0A8F6DXN6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

39122:KV203 RS04145
gene id: 39122:KV203_RS04145
uniprot id: A0A8F6HNR1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

39122:KV203 RS04115
gene id: 39122:KV203_RS04115
uniprot id: A0A8F6DZW1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

39122:KV203 RS08485
gene id: 39122:KV203_RS08485
uniprot id: A0A8F6DZ47
names: Similarity
messages: Belongs to the HIBADH-related family.

39122:KV203 RS01330
gene id: 39122:KV203_RS01330
uniprot id: A0A8F6HN86
names: Subcellular Location Annotation
messages: Membrane

39122:KV203 RS01945
gene id: 39122:KV203_RS01945
uniprot id: A0A8F6E1X4
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

39122:KV203 RS03725
gene id: 39122:KV203_RS03725
uniprot id: A0A8F6DZL6
names: Similarity
messages: Belongs to the AccD/PCCB family.

39122:KV203 RS10495
gene id: 39122:KV203_RS10495
uniprot id: A0A8F6DY30
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

39122:KV203 RS03905
gene id: 39122:KV203_RS03905
uniprot id: A0A8F6E240
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

39122:KV203 RS07245
gene id: 39122:KV203_RS07245
uniprot id: A0A8F6HS55
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.

39122:KV203 RS07575
gene id: 39122:KV203_RS07575
uniprot id: A0A8F6DZ54
names: Similarity
messages: Belongs to the histone deacetylase family.

39122:KV203 RS04105
gene id: 39122:KV203_RS04105
uniprot id: A0A8F6E2M7
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

39122:KV203 RS06170
gene id: 39122:KV203_RS06170
uniprot id: A0A8F6DYC6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

39122:KV203 RS13885
gene id: 39122:KV203_RS13885
uniprot id: A0A8F6DWS3
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
messages: Belongs to the nitrobindin family.
messages: Binds 1 heme b group per subunit, that coordinates a highly solvent-exposed Fe(III) atom.
messages: Forms a 10-stranded antiparallel beta-barrel structure able to accommodate a hydrophobic ligand in its interior. In fact, this fold hosts the heme group, which is located in a wide surface cleft.
messages: Heme-binding protein able to scavenge peroxynitrite and to protect free L-tyrosine against peroxynitrite-mediated nitration, by acting as a peroxynitrite isomerase that converts peroxynitrite to nitrate. Therefore, this protein likely plays a role in peroxynitrite sensing and in the detoxification of reactive nitrogen and oxygen species (RNS and ROS, respectively). Is able to bind nitric oxide (NO) in vitro, but may act as a sensor of peroxynitrite levels in vivo.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

39122:KV203 RS15220
gene id: 39122:KV203_RS15220
uniprot id: A0A8F6DV66
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

39122:KV203 RS10720
gene id: 39122:KV203_RS10720
uniprot id: A0A8F6DYJ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LamB/PxpA family.
messages: Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
messages: Forms a complex composed of PxpA, PxpB and PxpC.

39122:KV203 RS06085
gene id: 39122:KV203_RS06085
uniprot id: A0A8F6DXR2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import.
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

39122:KV203 RS15435
gene id: 39122:KV203_RS15435
uniprot id: A0A8F6HME3
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

39122:KV203 RS05105
gene id: 39122:KV203_RS05105
uniprot id: A0A8F6HNU3
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

39122:KV203 RS18785
gene id: 39122:KV203_RS18785
uniprot id: A0A8F6DW73
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate.
messages: Homotrimer.

39122:KV203 RS04155
gene id: 39122:KV203_RS04155
uniprot id: A0A8F6HRM7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

39122:KV203 RS03515
gene id: 39122:KV203_RS03515
uniprot id: A0A8F6DXI6
names: Similarity
messages: Belongs to the AccD/PCCB family.

39122:KV203 RS17420
gene id: 39122:KV203_RS17420
uniprot id: A0A8F6HP96
names: Similarity
messages: Belongs to the YoeB family.

39122:KV203 RS09165
gene id: 39122:KV203_RS09165
uniprot id: A0A8F6DZA0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

39122:KV203 RS02950
gene id: 39122:KV203_RS02950
uniprot id: A0A8F6HNI7
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

39122:KV203 RS11675
gene id: 39122:KV203_RS11675
uniprot id: A0A8F6HLW9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

39122:KV203 RS15815
gene id: 39122:KV203_RS15815
uniprot id: A0A8F6DVC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

39122:KV203 RS17050
gene id: 39122:KV203_RS17050
uniprot id: A0A8F6DVY0
names: Similarity
messages: Belongs to the glycosyltransferase 20 family.

39122:KV203 RS15050
gene id: 39122:KV203_RS15050
uniprot id: A0A8F6DW95
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

39122:KV203 RS07895
gene id: 39122:KV203_RS07895
uniprot id: A0A8F6HQR1
names: Similarity
messages: Belongs to the FAD-binding monooxygenase family.

39122:KV203 RS09775
gene id: 39122:KV203_RS09775
uniprot id: A0A8F6E0L5
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

39122:KV203 RS00460
gene id: 39122:KV203_RS00460
uniprot id: A0A8F6E1G6
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

39122:KV203 RS18200
gene id: 39122:KV203_RS18200
uniprot id: A0A8F6E0P3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

39122:KV203 RS04200
gene id: 39122:KV203_RS04200
uniprot id: A0A8F6DZX1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

39122:KV203 RS08210
gene id: 39122:KV203_RS08210
uniprot id: A0A8F6DYC5
names: Similarity
messages: Belongs to the TPP enzyme family.

39122:KV203 RS12910
gene id: 39122:KV203_RS12910
uniprot id: A0A8F6DTW7
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: May be specifically involved in the processing, transport, and/or maturation of the MADH beta-subunit.
messages: Membrane

39122:KV203 RS11805
gene id: 39122:KV203_RS11805
uniprot id: A0A8F6E540
names: Subcellular Location Annotation
messages: Membrane

39122:KV203 RS11760
gene id: 39122:KV203_RS11760
uniprot id: A0A8F6DV75
names: Similarity
messages: Belongs to the group II decarboxylase family.

39122:KV203 RS17370
gene id: 39122:KV203_RS17370
uniprot id: A0A8F6E0M6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

39122:KV203 RS03325
gene id: 39122:KV203_RS03325
uniprot id: A0A8F6E2D8
names: Caution
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
messages: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

39122:KV203 RS04545
gene id: 39122:KV203_RS04545
uniprot id: A0A8F6HNR5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

39122:KV203 RS10195
gene id: 39122:KV203_RS10195
uniprot id: A0A8F6DXR6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

39122:KV203 RS03315
gene id: 39122:KV203_RS03315
uniprot id: A0A8F6DXH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane

39122:KV203 RS15460
gene id: 39122:KV203_RS15460
uniprot id: A0A8F6DV78
names: Caution
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

39122:KV203 RS15670
gene id: 39122:KV203_RS15670
uniprot id: A0A8F6E051
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

39122:KV203 RS01635
gene id: 39122:KV203_RS01635
uniprot id: A0A8F6DWW2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homotetramer.

39122:KV203 RS13300
gene id: 39122:KV203_RS13300
uniprot id: A0A8F6DZ18
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-to-5' exoribonuclease specific for small oligoribonucleotides.
messages: Belongs to the oligoribonuclease family.
messages: Cytoplasm

39122:KV203 RS02930
gene id: 39122:KV203_RS02930
uniprot id: A0A8F6DZG3
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

39122:KV203 RS10295
gene id: 39122:KV203_RS10295
uniprot id: A0A8F6DTJ7
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

39122:KV203 RS11820
gene id: 39122:KV203_RS11820
uniprot id: A0A8F6DU21
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

39122:KV203 RS10290
gene id: 39122:KV203_RS10290
uniprot id: A0A8F6DTM1
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.

39122:KV203 RS18060
gene id: 39122:KV203_RS18060
uniprot id: A0A8F6DVZ7
names: Caution
names: Similarity
messages: Belongs to the globin family. Two-domain flavohemoproteins subfamily.
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

39122:KV203 RS12325
gene id: 39122:KV203_RS12325
uniprot id: A0A8F6HM05
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

39122:KV203 RS04055
gene id: 39122:KV203_RS04055
uniprot id: A0A8F6HNN7
names: Similarity
messages: Belongs to the cytochrome P450 family.

39122:KV203 RS00445
gene id: 39122:KV203_RS00445
uniprot id: A0A8F6DVY9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Molecular chaperone. Has ATPase activity.

39122:KV203 RS13595
gene id: 39122:KV203_RS13595
uniprot id: A0A8F6DYY9
names: Similarity
messages: Belongs to the cytochrome P450 family.

39122:KV203 RS17515
gene id: 39122:KV203_RS17515
uniprot id: A0A8F6E069
names: Similarity
messages: Belongs to the 4-hydroxy-2-oxovalerate aldolase family.

39122:KV203 RS05225
gene id: 39122:KV203_RS05225
uniprot id: A0A8F6DY29
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

39122:KV203 RS17810
gene id: 39122:KV203_RS17810
uniprot id: A0A8F6DVX5
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

39122:KV203 RS16240
gene id: 39122:KV203_RS16240
uniprot id: A0A8F6E0F9
names: Subcellular Location Annotation
messages: Membrane

39122:KV203 RS03870
gene id: 39122:KV203_RS03870
uniprot id: A0A8F6E2D2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

39122:KV203 RS03635
gene id: 39122:KV203_RS03635
uniprot id: A0A8F6E2A5
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

39122:KV203 RS16940
gene id: 39122:KV203_RS16940
uniprot id: A0A8F6E0H3
names: Similarity
messages: Belongs to the SAICAR synthetase family.

39122:KV203 RS05320
gene id: 39122:KV203_RS05320
uniprot id: A0A8F6DXH6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

39122:KV203 RS07585
gene id: 39122:KV203_RS07585
uniprot id: A0A8F6HP80
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

39122:KV203 RS02485
gene id: 39122:KV203_RS02485
uniprot id: A0A8F6HNG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

39122:KV203 RS18455
gene id: 39122:KV203_RS18455
uniprot id: A0A8F6DWE6
names: Similarity
messages: Belongs to the pirin family.

39122:KV203 RS11500
gene id: 39122:KV203_RS11500
uniprot id: A0A8F6DVV6
names: Similarity
messages: Belongs to the TrpC family.

39122:KV203 RS07230
gene id: 39122:KV203_RS07230
uniprot id: A0A8F6E087
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.

39122:KV203 RS03400
gene id: 39122:KV203_RS03400
uniprot id: A0A8F6HPF1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

39122:KV203 RS18735
gene id: 39122:KV203_RS18735
uniprot id: A0A8F6E0V3
names: Similarity
messages: Belongs to the 6-phosphogluconate dehydrogenase family.

39122:KV203 RS01610
gene id: 39122:KV203_RS01610
uniprot id: A0A8F6HPT0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MurCDEF family. MurT subfamily.
messages: Forms a heterodimer with GatD.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The MurT subunit catalyzes the ATP-dependent amidation of D-glutamate residue of lipid II, converting it to an isoglutamine residue.

39122:KV203 RS05940
gene id: 39122:KV203_RS05940
uniprot id: A0A8F6E317
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

39122:KV203 RS01565
gene id: 39122:KV203_RS01565
uniprot id: A0A8F6DWX1
names: Similarity
messages: Belongs to the CdaR family.

39122:KV203 RS05245
gene id: 39122:KV203_RS05245
uniprot id: A0A8F6E306
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

39122:KV203 RS09990
gene id: 39122:KV203_RS09990
uniprot id: A0A8F6DVC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CbxX/CfxQ family.
messages: Cytoplasm

39122:KV203 RS15990
gene id: 39122:KV203_RS15990
uniprot id: A0A8F6DVD9
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

39122:KV203 RS04190
gene id: 39122:KV203_RS04190
uniprot id: A0A8F6E2N6
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

39122:KV203 RS08780
gene id: 39122:KV203_RS08780
uniprot id: A0A8F6HSE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VKOR family.
messages: Membrane

39122:KV203 RS15830
gene id: 39122:KV203_RS15830
uniprot id: A0A8F6DVD0
names: Similarity
messages: Belongs to the IucA/IucC family.

39122:KV203 RS17760
gene id: 39122:KV203_RS17760
uniprot id: A0A8F6HMU0
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Catalyzes the reversible hydration of carbon dioxide to form bicarbonate.
messages: Reversible hydration of carbon dioxide.

39122:KV203 RS08200
gene id: 39122:KV203_RS08200
uniprot id: A0A8F6DYZ4
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

39122:KV203 RS11240
gene id: 39122:KV203_RS11240
uniprot id: A0A8F6HLU6
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

39122:KV203 RS11140
gene id: 39122:KV203_RS11140
uniprot id: A0A8F6DYA5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

39122:KV203 RS11075
gene id: 39122:KV203_RS11075
uniprot id: A0A8F6DTB8
names: Similarity
messages: Belongs to the TlyA family.

39122:KV203 RS07985
gene id: 39122:KV203_RS07985
uniprot id: A0A8F6HPD9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

39122:KV203 RS05395
gene id: 39122:KV203_RS05395
uniprot id: A0A8F6HPQ7
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

39122:KV203 RS05045
gene id: 39122:KV203_RS05045
uniprot id: A0A8F6E2Y7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

39122:KV203 RS08885
gene id: 39122:KV203_RS08885
uniprot id: A0A8F6DZ70
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

39122:KV203 RS06695
gene id: 39122:KV203_RS06695
uniprot id: A0A8F6HP32
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

39122:KV203 RS04005
gene id: 39122:KV203_RS04005
uniprot id: A0A8F6E248
names: Similarity
messages: Belongs to the long-chain O-acyltransferase family.

39122:KV203 RS09555
gene id: 39122:KV203_RS09555
uniprot id: A0A8F6DZD7
names: Similarity
messages: Belongs to the transposase 7 family.

39122:KV203 RS11745
gene id: 39122:KV203_RS11745
uniprot id: A0A8F6DU24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

39122:KV203 RS15660
gene id: 39122:KV203_RS15660
uniprot id: A0A8F6DVA9
names: Similarity
messages: Belongs to the AccD/PCCB family.

39122:KV203 RS17965
gene id: 39122:KV203_RS17965
uniprot id: A0A8F6DVY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

39122:KV203 RS10970
gene id: 39122:KV203_RS10970
uniprot id: A0A8F6HRA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

39122:KV203 RS15130
gene id: 39122:KV203_RS15130
uniprot id: A0A8F6HQS4
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

39122:KV203 RS18040
gene id: 39122:KV203_RS18040
uniprot id: A0A8F6HQN5
names: Similarity
messages: Belongs to the phosphohexose mutase family.

39122:KV203 RS13960
gene id: 39122:KV203_RS13960
uniprot id: A0A8F6DZM2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

39122:KV203 RS19470
gene id: 39122:KV203_RS19470
uniprot id: A0A8F6E133
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

39122:KV203 RS15360
gene id: 39122:KV203_RS15360
uniprot id: A0A8F6DZJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

39122:KV203 RS07740
gene id: 39122:KV203_RS07740
uniprot id: A0A8F6DYU6
names: Similarity
messages: Belongs to the AHA1 family.

39122:KV203 RS13995
gene id: 39122:KV203_RS13995
uniprot id: A0A8F6HNS6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

39122:KV203 RS12585
gene id: 39122:KV203_RS12585
uniprot id: A0A8F6DVG9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Heterodimer of an alpha and a beta subunit.
messages: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

39122:KV203 RS11040
gene id: 39122:KV203_RS11040
uniprot id: A0A8F6HLT7
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

39122:KV203 RS06340
gene id: 39122:KV203_RS06340
uniprot id: A0A8F6DZR8
names: Subcellular Location Annotation
messages: Membrane

39122:KV203 RS08265
gene id: 39122:KV203_RS08265
uniprot id: A0A8F6HQS8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

39122:KV203 RS00220
gene id: 39122:KV203_RS00220
uniprot id: A0A8F6HQZ1
names: Subcellular Location Annotation
messages: Membrane

39122:KV203 RS15925
gene id: 39122:KV203_RS15925
uniprot id: A0A8F6DVE1
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family. MbtB subfamily.

39122:KV203 RS04150
gene id: 39122:KV203_RS04150
uniprot id: A0A8F6HQ68
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

39122:KV203 RS07475
gene id: 39122:KV203_RS07475
uniprot id: A0A8F6DZ46
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

39122:KV203 RS13680
gene id: 39122:KV203_RS13680
uniprot id: A0A8F6HN13
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

39122:KV203 RS08680
gene id: 39122:KV203_RS08680
uniprot id: A0A8F6DZG9
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: Could possibly oxidize fatty acids using specific components.

39122:KV203 RS06580
gene id: 39122:KV203_RS06580
uniprot id: A0A8F6DYF8
names: Function
names: Similarity
messages: Belongs to the GlnE family.
messages: Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell.

39122:KV203 RS06000
gene id: 39122:KV203_RS06000
uniprot id: A0A8F6DZP5
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

39122:KV203 RS19090
gene id: 39122:KV203_RS19090
uniprot id: A0A8F6DXG7
names: Subcellular Location Annotation
messages: Membrane

39122:KV203 RS01265
gene id: 39122:KV203_RS01265
uniprot id: A0A8F6DWS2
names: Similarity
messages: Belongs to the Vsr family.

39122:KV203 RS13980
gene id: 39122:KV203_RS13980
uniprot id: A0A8F6DV10
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

39122:KV203 RS17690
gene id: 39122:KV203_RS17690
uniprot id: A0A8F6HQL2
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

39122:KV203 RS01655
gene id: 39122:KV203_RS01655
uniprot id: A0A8F6E1U3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

39122:KV203 RS01525
gene id: 39122:KV203_RS01525
uniprot id: A0A8F6HPK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Membrane

39122:KV203 RS16110
gene id: 39122:KV203_RS16110
uniprot id: A0A8F6DWL0
names: Subcellular Location Annotation
messages: Membrane

39122:KV203 RS14600
gene id: 39122:KV203_RS14600
uniprot id: A0A8F6DV06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

39122:KV203 RS01710
gene id: 39122:KV203_RS01710
uniprot id: A0A8F6HR80
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

39122:KV203 RS10395
gene id: 39122:KV203_RS10395
uniprot id: A0A8F6DTK8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 2 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

39122:KV203 RS03125
gene id: 39122:KV203_RS03125
uniprot id: A0A8F6HNJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MenA family. Type 1 subfamily.
messages: Cell membrane
messages: Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).
messages: Membrane

39122:KV203 RS07070
gene id: 39122:KV203_RS07070
uniprot id: A0A8F6HPY9
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

39122:KV203 RS14620
gene id: 39122:KV203_RS14620
uniprot id: A0A8F6DZI9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily.
messages: Cytoplasm
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

39122:KV203 RS11955
gene id: 39122:KV203_RS11955
uniprot id: A0A8F6DUA7
names: Similarity
messages: Belongs to the homogentisate dioxygenase family.

39122:KV203 RS15240
gene id: 39122:KV203_RS15240
uniprot id: A0A8F6DZR1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

39122:KV203 RS17485
gene id: 39122:KV203_RS17485
uniprot id: A0A8F6HMS7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

39122:KV203 RS05010
gene id: 39122:KV203_RS05010
uniprot id: A0A8F6HRT0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

39122:KV203 RS08175
gene id: 39122:KV203_RS08175
uniprot id: A0A8F6HPE9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

39122:KV203 RS18085
gene id: 39122:KV203_RS18085
uniprot id: A0A8F6DW04
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

39122:KV203 RS07500
gene id: 39122:KV203_RS07500
uniprot id: A0A8F6HS70
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

39122:KV203 RS17700
gene id: 39122:KV203_RS17700
uniprot id: A0A8F6E091
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

39122:KV203 RS16000
gene id: 39122:KV203_RS16000
uniprot id: A0A8F6DVF0
names: Activity Regulation
names: Caution
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

39122:KV203 RS04425
gene id: 39122:KV203_RS04425
uniprot id: A0A8F6E2R7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

39122:KV203 RS01445
gene id: 39122:KV203_RS01445
uniprot id: A0A8F6E189
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

39122:KV203 RS04165
gene id: 39122:KV203_RS04165
uniprot id: A0A8F6E269
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

39122:KV203 RS04980
gene id: 39122:KV203_RS04980
uniprot id: A0A8F6E2R5
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

39122:KV203 RS03005
gene id: 39122:KV203_RS03005
uniprot id: A0A8F6E296
names: Subcellular Location Annotation
messages: Membrane

39122:KV203 RS12970
gene id: 39122:KV203_RS12970
uniprot id: A0A8F6HNL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

39122:KV203 RS03430
gene id: 39122:KV203_RS03430
uniprot id: A0A8F6DXH9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

39122:KV203 RS15835
gene id: 39122:KV203_RS15835
uniprot id: A0A8F6E067
names: Cofactor
names: Similarity
messages: Belongs to the peptidase S45 family.
messages: Binds 1 Ca(2+) ion per dimer.

39122:KV203 RS16710
gene id: 39122:KV203_RS16710
uniprot id: A0A8F6HMK9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetyltransferase family. MshD subfamily.
messages: Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

39122:KV203 RS12995
gene id: 39122:KV203_RS12995
uniprot id: A0A8F6DTX6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

39122:KV203 RS08860
gene id: 39122:KV203_RS08860
uniprot id: A0A8F6HQW2
names: Subcellular Location Annotation
messages: Membrane

39122:KV203 RS02605
gene id: 39122:KV203_RS02605
uniprot id: A0A8F6HPY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

39122:KV203 RS07140
gene id: 39122:KV203_RS07140
uniprot id: A0A8F6HQM4
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

39122:KV203 RS06745
gene id: 39122:KV203_RS06745
uniprot id: A0A8F6E3H7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

39122:KV203 RS05855
gene id: 39122:KV203_RS05855
uniprot id: A0A8F6HQF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

39122:KV203 RS04760
gene id: 39122:KV203_RS04760
uniprot id: A0A8F6DXZ3
names: Function
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

39122:KV203 RS07490
gene id: 39122:KV203_RS07490
uniprot id: A0A8F6HPB3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

39122:KV203 RS03735
gene id: 39122:KV203_RS03735
uniprot id: A0A8F6HQ45
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

39122:KV203 RS03425
gene id: 39122:KV203_RS03425
uniprot id: A0A8F6DWW3
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

39122:KV203 RS09160
gene id: 39122:KV203_RS09160
uniprot id: A0A8F6E3R4
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

39122:KV203 RS13625
gene id: 39122:KV203_RS13625
uniprot id: A0A8F6DZI3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

39122:KV203 RS12560
gene id: 39122:KV203_RS12560
uniprot id: A0A8F6DU95
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

39122:KV203 RS18495
gene id: 39122:KV203_RS18495
uniprot id: A0A8F6E0V9
names: Similarity
messages: Belongs to the adenylyl cyclase class-3 family.

39122:KV203 RS12300
gene id: 39122:KV203_RS12300
uniprot id: A0A8F6DZ21
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

39122:KV203 RS08390
gene id: 39122:KV203_RS08390
uniprot id: A0A8F6DYE8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

39122:KV203 RS18900
gene id: 39122:KV203_RS18900
uniprot id: A0A8F6DW93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the encapsulin family. Family 1 subfamily.
messages: Encapsulin nanocompartment

39122:KV203 RS01970
gene id: 39122:KV203_RS01970
uniprot id: A0A8F6HNC4
names: Similarity
messages: Belongs to the peptidase M1 family.

39122:KV203 RS13555
gene id: 39122:KV203_RS13555
uniprot id: A0A8F6DZ53
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

39122:KV203 RS06420
gene id: 39122:KV203_RS06420
uniprot id: A0A8F6HP17
names: Function
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

39122:KV203 RS03490
gene id: 39122:KV203_RS03490
uniprot id: A0A8F6HNM4
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

39122:KV203 RS16880
gene id: 39122:KV203_RS16880
uniprot id: A0A8F6HMP4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

39122:KV203 RS06915
gene id: 39122:KV203_RS06915
uniprot id: A0A8F6DZQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 87 family.
messages: Membrane

39122:KV203 RS10690
gene id: 39122:KV203_RS10690
uniprot id: A0A8F6HMJ2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

39122:KV203 RS15420
gene id: 39122:KV203_RS15420
uniprot id: A0A8F6DZT6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

39122:KV203 RS10420
gene id: 39122:KV203_RS10420
uniprot id: A0A8F6DY19
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

39122:KV203 RS09540
gene id: 39122:KV203_RS09540
uniprot id: A0A8F6HPS8
names: Similarity
messages: Belongs to the peptidase U62 family.

39122:KV203 RS09955
gene id: 39122:KV203_RS09955
uniprot id: A0A8F6DXN4
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

39122:KV203 RS03860
gene id: 39122:KV203_RS03860
uniprot id: A0A8F6DYU8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

39122:KV203 RS17805
gene id: 39122:KV203_RS17805
uniprot id: A0A8F6DVX4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

39122:KV203 RS06400
gene id: 39122:KV203_RS06400
uniprot id: A0A8F6DZK7
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

39122:KV203 RS10255
gene id: 39122:KV203_RS10255
uniprot id: A0A8F6HLI2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic Ku family.
messages: Homodimer. Interacts with LigD.
messages: With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD.

39122:KV203 RS19220
gene id: 39122:KV203_RS19220
uniprot id: A0A8F6E0Q5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

39122:KV203 RS06155
gene id: 39122:KV203_RS06155
uniprot id: A0A8F6HRZ3
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

39122:KV203 RS10625
gene id: 39122:KV203_RS10625
uniprot id: A0A8F6DT70
names: Subcellular Location Annotation
messages: Membrane

39122:KV203 RS17390
gene id: 39122:KV203_RS17390
uniprot id: A0A8F6E0F7
names: Similarity
messages: Belongs to the acetaldehyde dehydrogenase family.

39122:KV203 RS02780
gene id: 39122:KV203_RS02780
uniprot id: A0A8F6HRE3
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

39122:KV203 RS04505
gene id: 39122:KV203_RS04505
uniprot id: A0A8F6DZN7
names: Subcellular Location Annotation
messages: Membrane

39122:KV203 RS09670
gene id: 39122:KV203_RS09670
uniprot id: A0A8F6E0K4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

39122:KV203 RS12050
gene id: 39122:KV203_RS12050
uniprot id: A0A8F6HNG8
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

39122:KV203 RS01995
gene id: 39122:KV203_RS01995
uniprot id: A0A8F6HP68
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

39122:KV203 RS02490
gene id: 39122:KV203_RS02490
uniprot id: A0A8F6HPX6
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

39122:KV203 RS03895
gene id: 39122:KV203_RS03895
uniprot id: A0A8F6HRL2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

39122:KV203 RS14685
gene id: 39122:KV203_RS14685
uniprot id: A0A8F6DUF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Membrane

39122:KV203 RS03135
gene id: 39122:KV203_RS03135
uniprot id: A0A8F6HRG3
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

39122:KV203 RS12230
gene id: 39122:KV203_RS12230
uniprot id: A0A8F6DUE0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

39122:KV203 RS03780
gene id: 39122:KV203_RS03780
uniprot id: A0A8F6E2I5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Membrane

39122:KV203 RS09545
gene id: 39122:KV203_RS09545
uniprot id: A0A8F6HQC3
names: Similarity
messages: Belongs to the peptidase U62 family.

39122:KV203 RS14065
gene id: 39122:KV203_RS14065
uniprot id: A0A8F6DZN0
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

39122:KV203 RS04420
gene id: 39122:KV203_RS04420
uniprot id: A0A8F6DXT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

39122:KV203 RS08385
gene id: 39122:KV203_RS08385
uniprot id: A0A8F6DZ12
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

39122:KV203 RS13270
gene id: 39122:KV203_RS13270
uniprot id: A0A8F6DU06
names: Subcellular Location Annotation
messages: Membrane

39122:KV203 RS03580
gene id: 39122:KV203_RS03580
uniprot id: A0A8F6HRJ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

39122:KV203 RS04625
gene id: 39122:KV203_RS04625
uniprot id: A0A8F6HNS0
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

39122:KV203 RS07040
gene id: 39122:KV203_RS07040
uniprot id: A0A8F6DYZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

39122:KV203 RS08975
gene id: 39122:KV203_RS08975
uniprot id: A0A8F6DYL2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

39122:KV203 RS11965
gene id: 39122:KV203_RS11965
uniprot id: A0A8F6HLS8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

39122:KV203 RS03560
gene id: 39122:KV203_RS03560
uniprot id: A0A8F6DXV4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

39122:KV203 RS06295
gene id: 39122:KV203_RS06295
uniprot id: A0A8F6DYC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

39122:KV203 RS08850
gene id: 39122:KV203_RS08850
uniprot id: A0A8F6HPX8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

39122:KV203 RS16030
gene id: 39122:KV203_RS16030
uniprot id: A0A8F6E005
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: Homotrimer.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. Cleaves guanosine, inosine, 2'-deoxyguanosine and 2'-deoxyinosine.

39122:KV203 RS06395
gene id: 39122:KV203_RS06395
uniprot id: A0A8F6E3D9
names: Similarity
messages: Belongs to the AccD/PCCB family.

39122:KV203 RS11070
gene id: 39122:KV203_RS11070
uniprot id: A0A8F6DTU8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

39122:KV203 RS13455
gene id: 39122:KV203_RS13455
uniprot id: A0A8F6DUM6
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

39122:KV203 RS00200
gene id: 39122:KV203_RS00200
uniprot id: A0A8F6HN23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

39122:KV203 RS04870
gene id: 39122:KV203_RS04870
uniprot id: A0A8F6E2Q5
names: Similarity
messages: Belongs to the CFA/CMAS family.

39122:KV203 RS12160
gene id: 39122:KV203_RS12160
uniprot id: A0A8F6HPM1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: A probable RNA-binding protein.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm

39122:KV203 RS16150
gene id: 39122:KV203_RS16150
uniprot id: A0A8F6HQC6
names: Cofactor
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

39122:KV203 RS12890
gene id: 39122:KV203_RS12890
uniprot id: A0A8F6HPR6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial microcompartment
messages: Belongs to the EutC family.
messages: Binds between the large and small subunits.
messages: Catalyzes the deamination of various vicinal amino-alcohols to oxo compounds. Allows this organism to utilize ethanolamine as the sole source of nitrogen and carbon in the presence of external vitamin B12.
messages: The basic unit is a heterodimer which dimerizes to form tetramers. The heterotetramers trimerize; 6 large subunits form a core ring with 6 small subunits projecting outwards.

39122:KV203 RS14910
gene id: 39122:KV203_RS14910
uniprot id: A0A8F6DVA8
names: Similarity
messages: Belongs to the glycosyl hydrolase 38 family.

39122:KV203 RS11355
gene id: 39122:KV203_RS11355
uniprot id: A0A8F6DTX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial phospholipase C family.
messages: cell wall

39122:KV203 RS14635
gene id: 39122:KV203_RS14635
uniprot id: A0A8F6HM95
names: Subcellular Location Annotation
messages: Membrane

39122:KV203 RS14380
gene id: 39122:KV203_RS14380
uniprot id: A0A8F6E0M4
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.

39122:KV203 RS07950
gene id: 39122:KV203_RS07950
uniprot id: A0A8F6DYV8
names: Subunit
messages: Heterodimer of an alpha and a beta chain.

39122:KV203 RS03470
gene id: 39122:KV203_RS03470
uniprot id: A0A8F6DZM7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

39122:KV203 RS07085
gene id: 39122:KV203_RS07085
uniprot id: A0A8F6DY09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DivIVA family.
messages: Cytoplasm

39122:KV203 RS00535
gene id: 39122:KV203_RS00535
uniprot id: A0A8F6DWL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDT1 family.
messages: Membrane

39122:KV203 RS15035
gene id: 39122:KV203_RS15035
uniprot id: A0A8F6DV36
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

39122:KV203 RS17720
gene id: 39122:KV203_RS17720
uniprot id: A0A8F6DVW4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

39122:KV203 RS18025
gene id: 39122:KV203_RS18025
uniprot id: A0A8F6HMV6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

39122:KV203 RS05230
gene id: 39122:KV203_RS05230
uniprot id: A0A8F6DXG6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

39122:KV203 RS08730
gene id: 39122:KV203_RS08730
uniprot id: A0A8F6DZ35
names: Similarity
messages: Belongs to the cytochrome P450 family.

39122:KV203 RS19475
gene id: 39122:KV203_RS19475
uniprot id: A0A8F6HQ89
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

39122:KV203 RS10575
gene id: 39122:KV203_RS10575
uniprot id: A0A8F6DVJ8
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD.
messages: Belongs to the RecD family.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding.

39122:KV203 RS00295
gene id: 39122:KV203_RS00295
uniprot id: A0A8F6HN44
names: Similarity
messages: Belongs to the peptidase S9C family.

39122:KV203 RS04795
gene id: 39122:KV203_RS04795
uniprot id: A0A8F6DYB2
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: Could possibly oxidize fatty acids using specific components.

39122:KV203 RS12505
gene id: 39122:KV203_RS12505
uniprot id: A0A8F6DYS3
names: Subcellular Location Annotation
messages: Membrane

39122:KV203 RS11220
gene id: 39122:KV203_RS11220
uniprot id: A0A8F6DV15
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

39122:KV203 RS08490
gene id: 39122:KV203_RS08490
uniprot id: A0A8F6DZ08
names: Subcellular Location Annotation
messages: Membrane

39122:KV203 RS02310
gene id: 39122:KV203_RS02310
uniprot id: A0A8F6HNE8
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain.

39122:KV203 RS09740
gene id: 39122:KV203_RS09740
uniprot id: A0A8F6DYU2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM61 family.
messages: Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA.
messages: Homotetramer composed of a dimer of dimers.

39122:KV203 RS00775
gene id: 39122:KV203_RS00775
uniprot id: A0A8F6DWM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

39122:KV203 RS02445
gene id: 39122:KV203_RS02445
uniprot id: A0A8F6DX56
names: Function
names: Similarity
messages: Belongs to the ATP-dependent DNA ligase family.
messages: DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair.

39122:KV203 RS02840
gene id: 39122:KV203_RS02840
uniprot id: A0A8F6E206
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

39122:KV203 RS08335
gene id: 39122:KV203_RS08335
uniprot id: A0A8F6DZC9
names: Similarity
messages: Belongs to the Arg-specific ADP-ribosyltransferase family.

39122:KV203 RS14555
gene id: 39122:KV203_RS14555
uniprot id: A0A8F6HM90
names: Similarity
messages: Belongs to the universal stress protein A family.

39122:KV203 RS01920
gene id: 39122:KV203_RS01920
uniprot id: A0A8F6DWZ3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

39122:KV203 RS10135
gene id: 39122:KV203_RS10135
uniprot id: A0A8F6DTK0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

39122:KV203 RS06245
gene id: 39122:KV203_RS06245
uniprot id: A0A8F6HPV3
names: Similarity
messages: Belongs to the dGTPase family. Type 2 subfamily.

39122:KV203 RS18245
gene id: 39122:KV203_RS18245
uniprot id: A0A8F6DW17
names: Subcellular Location Annotation
messages: Membrane

39122:KV203 RS11600
gene id: 39122:KV203_RS11600
uniprot id: A0A8F6HLQ6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

39122:KV203 RS14060
gene id: 39122:KV203_RS14060
uniprot id: A0A8F6DUV2
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

39122:KV203 RS05040
gene id: 39122:KV203_RS05040
uniprot id: A0A8F6DXZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

39122:KV203 RS08180
gene id: 39122:KV203_RS08180
uniprot id: A0A8F6HQS3
names: Subcellular Location Annotation
messages: Membrane

39122:KV203 RS16370
gene id: 39122:KV203_RS16370
uniprot id: A0A8F6HMM3
names: Similarity
messages: Belongs to the helicase family. RAD25/XPB subfamily.

39122:KV203 RS07460
gene id: 39122:KV203_RS07460
uniprot id: A0A8F6E4C8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

39122:KV203 RS10630
gene id: 39122:KV203_RS10630
uniprot id: A0A8F6DTQ7
names: Subcellular Location Annotation
messages: Membrane

39122:KV203 RS10275
gene id: 39122:KV203_RS10275
uniprot id: A0A8F6DXS8
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

39122:KV203 RS18280
gene id: 39122:KV203_RS18280
uniprot id: A0A8F6DY63
names: Similarity
messages: Belongs to the pirin family.

39122:KV203 RS12155
gene id: 39122:KV203_RS12155
uniprot id: A0A8F6HNH5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

39122:KV203 RS19295
gene id: 39122:KV203_RS19295
uniprot id: A0A8F6E0L2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

39122:KV203 RS08245
gene id: 39122:KV203_RS08245
uniprot id: A0A8F6DZC2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

39122:KV203 RS07175
gene id: 39122:KV203_RS07175
uniprot id: A0A8F6DY17
names: Similarity
messages: Belongs to the FAD-binding monooxygenase family.

39122:KV203 RS08960
gene id: 39122:KV203_RS08960
uniprot id: A0A8F6HQ92
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

39122:KV203 RS04740
gene id: 39122:KV203_RS04740
uniprot id: A0A8F6E2D7
names: Similarity
messages: Belongs to the peptidase S51 family.

39122:KV203 RS12315
gene id: 39122:KV203_RS12315
uniprot id: A0A8F6DYP9
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

39122:KV203 RS19215
gene id: 39122:KV203_RS19215
uniprot id: A0A8F6HNV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

39122:KV203 RS03585
gene id: 39122:KV203_RS03585
uniprot id: A0A8F6HPG1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

39122:KV203 RS03975
gene id: 39122:KV203_RS03975
uniprot id: A0A8F6E4G6
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

39122:KV203 RS06310
gene id: 39122:KV203_RS06310
uniprot id: A0A8F6E0I2
names: Caution
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

39122:KV203 RS12495
gene id: 39122:KV203_RS12495
uniprot id: A0A8F6DVF9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

39122:KV203 RS15525
gene id: 39122:KV203_RS15525
uniprot id: A0A8F6HMI0
names: Function
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Involved in the hydrocarbon hydroxylating system, which transfers electrons from NADH to rubredoxin reductase and then through rubredoxin to alkane 1 monooxygenase.

39122:KV203 RS02915
gene id: 39122:KV203_RS02915
uniprot id: A0A8F6E286
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

39122:KV203 RS16850
gene id: 39122:KV203_RS16850
uniprot id: A0A8F6E0G3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

39122:KV203 RS12280
gene id: 39122:KV203_RS12280
uniprot id: A0A8F6DTP3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

39122:KV203 RS12485
gene id: 39122:KV203_RS12485
uniprot id: A0A8F6DUB0
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

39122:KV203 RS12100
gene id: 39122:KV203_RS12100
uniprot id: A0A8F6HQ12
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

39122:KV203 RS05955
gene id: 39122:KV203_RS05955
uniprot id: A0A8F6HNZ3
names: Similarity
messages: Belongs to the EspG family.

39122:KV203 RS18125
gene id: 39122:KV203_RS18125
uniprot id: A0A8F6HMW0
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

39122:KV203 RS08215
gene id: 39122:KV203_RS08215
uniprot id: A0A8F6DZ13
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

39122:KV203 RS13950
gene id: 39122:KV203_RS13950
uniprot id: A0A8F6DUS1
names: Similarity
messages: Belongs to the AP endonuclease 2 family.

39122:KV203 RS18010
gene id: 39122:KV203_RS18010
uniprot id: A0A8F6DY33
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

39122:KV203 RS17150
gene id: 39122:KV203_RS17150
uniprot id: A0A8F6HP83
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

39122:KV203 RS02415
gene id: 39122:KV203_RS02415
uniprot id: A0A8F6DX57
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

39122:KV203 RS04995
gene id: 39122:KV203_RS04995
uniprot id: A0A8F6HNT8
names: Subcellular Location Annotation
messages: Membrane

39122:KV203 RS07395
gene id: 39122:KV203_RS07395
uniprot id: A0A8F6HPA6
names: Function
names: Similarity
names: Subunit
messages: APS kinase catalyzes the synthesis of activated sulfate.
messages: Belongs to the APS kinase family.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
messages: Catalyzes the synthesis of activated sulfate.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: In the C-terminal section; belongs to the APS kinase family.
messages: In the N-terminal section; belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
messages: With CysD forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

39122:KV203 RS09210
gene id: 39122:KV203_RS09210
uniprot id: A0A8F6E0E9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

39122:KV203 RS02920
gene id: 39122:KV203_RS02920
uniprot id: A0A8F6DZL1
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

39122:KV203 RS11135
gene id: 39122:KV203_RS11135
uniprot id: A0A8F6DVR3
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

39122:KV203 RS12455
gene id: 39122:KV203_RS12455
uniprot id: A0A8F6HMU1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

39122:KV203 RS07390
gene id: 39122:KV203_RS07390
uniprot id: A0A8F6HP71
names: Similarity
messages: Belongs to the PAPS reductase family. CysD subfamily.

39122:KV203 RS17870
gene id: 39122:KV203_RS17870
uniprot id: A0A8F6HNN0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

39122:KV203 RS03890
gene id: 39122:KV203_RS03890
uniprot id: A0A8F6HQ53
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

39122:KV203 RS04305
gene id: 39122:KV203_RS04305
uniprot id: A0A8F6HQ77
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

39122:KV203 RS15285
gene id: 39122:KV203_RS15285
uniprot id: A0A8F6DUL2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

39122:KV203 RS12165
gene id: 39122:KV203_RS12165
uniprot id: A0A8F6HMS3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

39122:KV203 RS10965
gene id: 39122:KV203_RS10965
uniprot id: A0A8F6HLM1
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

39122:KV203 RS09855
gene id: 39122:KV203_RS09855
uniprot id: A0A8F6HN51
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

39122:KV203 RS06130
gene id: 39122:KV203_RS06130
uniprot id: A0A8F6DYQ2
names: Function
messages: Catalyzes the reduction of sulfite to sulfide, a step in the biosynthesis of sulfur-containing amino acids and cofactors.

39122:KV203 RS15385
gene id: 39122:KV203_RS15385
uniprot id: A0A8F6DV85
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

39122:KV203 RS00865
gene id: 39122:KV203_RS00865
uniprot id: A0A8F6E127
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

39122:KV203 RS11705
gene id: 39122:KV203_RS11705
uniprot id: A0A8F6DZG6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

39122:KV203 RS03640
gene id: 39122:KV203_RS03640
uniprot id: A0A8F6DXW5
names: Similarity
messages: Belongs to the CsoR family.

39122:KV203 RS07430
gene id: 39122:KV203_RS07430
uniprot id: A0A8F6DYT6
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

39122:KV203 RS11110
gene id: 39122:KV203_RS11110
uniprot id: A0A8F6DTU1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

39122:KV203 RS17425
gene id: 39122:KV203_RS17425
uniprot id: A0A8F6HQJ7
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

39122:KV203 RS05910
gene id: 39122:KV203_RS05910
uniprot id: A0A8F6E387
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

39122:KV203 RS19400
gene id: 39122:KV203_RS19400
uniprot id: A0A8F6HN09
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

39122:KV203 RS14590
gene id: 39122:KV203_RS14590
uniprot id: A0A8F6DUE4
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

39122:KV203 RS01125
gene id: 39122:KV203_RS01125
uniprot id: A0A8F6HN74
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

39122:KV203 RS10045
gene id: 39122:KV203_RS10045
uniprot id: A0A8F6DT08
names: Similarity
messages: Belongs to the SAM hydrolase / SAM-dependent halogenase family.

39122:KV203 RS00390
gene id: 39122:KV203_RS00390
uniprot id: A0A8F6E173
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class II aldolase/RraA-like family.
messages: Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions.
messages: Homotrimer.

39122:KV203 RS08100
gene id: 39122:KV203_RS08100
uniprot id: A0A8F6HQ42
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

39122:KV203 RS08525
gene id: 39122:KV203_RS08525
uniprot id: A0A8F6HPG9
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

39122:KV203 RS09865
gene id: 39122:KV203_RS09865
uniprot id: A0A8F6HME5
names: Similarity
messages: Belongs to the UPF0098 family.

39122:KV203 RS19430
gene id: 39122:KV203_RS19430
uniprot id: A0A8F6DVT9
names: Similarity
messages: Belongs to the ParB family.

39122:KV203 RS01025
gene id: 39122:KV203_RS01025
uniprot id: A0A8F6HN79
names: Subcellular Location Annotation
messages: Membrane

39122:KV203 RS18035
gene id: 39122:KV203_RS18035
uniprot id: A0A8F6HPC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

39122:KV203 RS14610
gene id: 39122:KV203_RS14610
uniprot id: A0A8F6DW53
names: Similarity
messages: Belongs to the transglycosylase family. Rpf subfamily.

39122:KV203 RS14880
gene id: 39122:KV203_RS14880
uniprot id: A0A8F6DZW2
names: Cofactor
messages: Binds 1 FAD per subunit.

39122:KV203 RS12920
gene id: 39122:KV203_RS12920
uniprot id: A0A8F6DUE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. TCR/Tet family.
messages: Membrane

39122:KV203 RS06405
gene id: 39122:KV203_RS06405
uniprot id: A0A8F6E0J4
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: Acyl carrier protein involved in meromycolate extension.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

39122:KV203 RS10390
gene id: 39122:KV203_RS10390
uniprot id: A0A8F6DTM7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

39122:KV203 RS04550
gene id: 39122:KV203_RS04550
uniprot id: A0A8F6HNT7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

39122:KV203 RS15505
gene id: 39122:KV203_RS15505
uniprot id: A0A8F6DX96
names: Similarity
messages: Belongs to the thymidylate kinase family.

39122:KV203 RS08805
gene id: 39122:KV203_RS08805
uniprot id: A0A8F6DYJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

39122:KV203 RS14515
gene id: 39122:KV203_RS14515
uniprot id: A0A8F6DUX9
names: Similarity
messages: Belongs to the universal stress protein A family.

39122:KV203 RS13530
gene id: 39122:KV203_RS13530
uniprot id: A0A8F6DUL5
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

39122:KV203 RS04100
gene id: 39122:KV203_RS04100
uniprot id: A0A8F6DXP6
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

39122:KV203 RS12815
gene id: 39122:KV203_RS12815
uniprot id: A0A8F6DTV7
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

39122:KV203 RS14050
gene id: 39122:KV203_RS14050
uniprot id: A0A8F6DU92
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl-inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics.
messages: Belongs to the MshB deacetylase family. Mca subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Monomer.

39122:KV203 RS06705
gene id: 39122:KV203_RS06705
uniprot id: A0A8F6HQK1
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

39122:KV203 RS04900
gene id: 39122:KV203_RS04900
uniprot id: A0A8F6HPN2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 independent methionine synthase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.

39122:KV203 RS07725
gene id: 39122:KV203_RS07725
uniprot id: A0A8F6HQ25
names: Subcellular Location Annotation
messages: Membrane

39122:KV203 RS14460
gene id: 39122:KV203_RS14460
uniprot id: A0A8F6DV60
names: Function
names: Similarity
names: Subunit
messages: Belongs to the methyltransferase superfamily. EgtD family.
messages: Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine.
messages: Monomer.

39122:KV203 RS11115
gene id: 39122:KV203_RS11115
uniprot id: A0A8F6DYN7
names: Similarity
messages: Belongs to the DNA glycosylase MPG family.

39122:KV203 RS03335
gene id: 39122:KV203_RS03335
uniprot id: A0A8F6DZN2
names: Function
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 1 subfamily.
messages: Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 2-succinylbenzoate (OSB).

39122:KV203 RS17585
gene id: 39122:KV203_RS17585
uniprot id: A0A8F6HPA5
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

39122:KV203 RS04350
gene id: 39122:KV203_RS04350
uniprot id: A0A8F6DZ02
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

39122:KV203 RS15280
gene id: 39122:KV203_RS15280
uniprot id: A0A8F6DV59
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

39122:KV203 RS12950
gene id: 39122:KV203_RS12950
uniprot id: A0A8F6DYX4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

39122:KV203 RS02970
gene id: 39122:KV203_RS02970
uniprot id: A0A8F6E1R9
names: Similarity
messages: Belongs to the acyl-CoA oxidase family.

39122:KV203 RS11715
gene id: 39122:KV203_RS11715
uniprot id: A0A8F6HPI8
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

39122:KV203 RS09385
gene id: 39122:KV203_RS09385
uniprot id: A0A8F6DZA6
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

39122:KV203 RS14825
gene id: 39122:KV203_RS14825
uniprot id: A0A8F6HME1
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

39122:KV203 RS06560
gene id: 39122:KV203_RS06560
uniprot id: A0A8F6E1W9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

39122:KV203 RS14930
gene id: 39122:KV203_RS14930
uniprot id: A0A8F6HQ43
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 5 (UDGb) family.

39122:KV203 RS06185
gene id: 39122:KV203_RS06185
uniprot id: A0A8F6DYB5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

39122:KV203 RS00520
gene id: 39122:KV203_RS00520
uniprot id: A0A8F6DWJ7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

39122:KV203 RS09790
gene id: 39122:KV203_RS09790
uniprot id: A0A8F6DZU9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MshC subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent condensation of GlcN-Ins and L-cysteine to form L-Cys-GlcN-Ins.
messages: Monomer.

39122:KV203 RS14360
gene id: 39122:KV203_RS14360
uniprot id: A0A8F6DV51
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

39122:KV203 RS04950
gene id: 39122:KV203_RS04950
uniprot id: A0A8F6DXY7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

39122:KV203 RS03100
gene id: 39122:KV203_RS03100
uniprot id: A0A8F6DYK2
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

39122:KV203 RS02615
gene id: 39122:KV203_RS02615
uniprot id: A0A8F6HPA2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

39122:KV203 RS09595
gene id: 39122:KV203_RS09595
uniprot id: A0A8F6E471
names: Subcellular Location Annotation
messages: Membrane

39122:KV203 RS03255
gene id: 39122:KV203_RS03255
uniprot id: A0A8F6DZL9
names: Function
messages: Long-chain fatty alcohol oxidase involved in the omega-oxidation pathway of lipid degradation.

39122:KV203 RS09705
gene id: 39122:KV203_RS09705
uniprot id: A0A8F6HPP0
names: Domain
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic ubiquitin-like protein family.
messages: Is modified by deamidation of its C-terminal glutamine to glutamate by the deamidase Dop, a prerequisite to the subsequent pupylation process.
messages: Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation.
messages: Strongly interacts with the proteasome-associated ATPase ARC through a hydrophobic interface; the interacting region of Pup lies in its C-terminal half. There is one Pup binding site per ARC hexamer ring.
messages: The N-terminal unstructured half of Pup provides a signal required to initiate unfolding and degradation by the proteasome but is not needed for pupylation, while the C-terminal helical half of Pup interacts with ARC to target proteins to the proteasome.

39122:KV203 RS08870
gene id: 39122:KV203_RS08870
uniprot id: A0A8F6HQ86
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

39122:KV203 RS01545
gene id: 39122:KV203_RS01545
uniprot id: A0A8F6DWV2
names: Cofactor
messages: Binds 1 FAD per subunit.
messages: Binds 1 FMN per subunit.

39122:KV203 RS07845
gene id: 39122:KV203_RS07845
uniprot id: A0A8F6DYU5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

39122:KV203 RS04340
gene id: 39122:KV203_RS04340
uniprot id: A0A8F6DXS4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

39122:KV203 RS17930
gene id: 39122:KV203_RS17930
uniprot id: A0A8F6DW86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Cell membrane
messages: Membrane

39122:KV203 RS14840
gene id: 39122:KV203_RS14840
uniprot id: A0A8F6HQ39
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

39122:KV203 RS15535
gene id: 39122:KV203_RS15535
uniprot id: A0A8F6HPX9
names: Subcellular Location Annotation
messages: Membrane

39122:KV203 RS16115
gene id: 39122:KV203_RS16115
uniprot id: A0A8F6DXG3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

39122:KV203 RS11855
gene id: 39122:KV203_RS11855
uniprot id: A0A8F6DW07
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

39122:KV203 RS18845
gene id: 39122:KV203_RS18845
uniprot id: A0A8F6DWI9
names: Similarity
messages: Belongs to the myo-inositol 1-phosphate synthase family.

39122:KV203 RS09225
gene id: 39122:KV203_RS09225
uniprot id: A0A8F6E430
names: Function
names: Similarity
messages: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
messages: Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines.

39122:KV203 RS00600
gene id: 39122:KV203_RS00600
uniprot id: A0A8F6E0Z5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

39122:KV203 RS04170
gene id: 39122:KV203_RS04170
uniprot id: A0A8F6DXR5
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

39122:KV203 RS12000
gene id: 39122:KV203_RS12000
uniprot id: A0A8F6DU45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

39122:KV203 RS04260
gene id: 39122:KV203_RS04260
uniprot id: A0A8F6DXR4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

39122:KV203 RS06465
gene id: 39122:KV203_RS06465
uniprot id: A0A8F6DYF5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

39122:KV203 RS11065
gene id: 39122:KV203_RS11065
uniprot id: A0A8F6DY27
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

39122:KV203 RS07820
gene id: 39122:KV203_RS07820
uniprot id: A0A8F6E3B5
names: Subcellular Location Annotation
messages: Membrane

39122:KV203 RS15550
gene id: 39122:KV203_RS15550
uniprot id: A0A8F6HNB3
names: Similarity
messages: Belongs to the phosphohexose mutase family.

39122:KV203 RS15140
gene id: 39122:KV203_RS15140
uniprot id: A0A8F6DV57
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

39122:KV203 RS04650
gene id: 39122:KV203_RS04650
uniprot id: A0A8F6HPM0
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

39122:KV203 RS04140
gene id: 39122:KV203_RS04140
uniprot id: A0A8F6HPM8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

39122:KV203 RS15905
gene id: 39122:KV203_RS15905
uniprot id: A0A8F6HND2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

39122:KV203 RS08970
gene id: 39122:KV203_RS08970
uniprot id: A0A8F6DZ81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

39122:KV203 RS04210
gene id: 39122:KV203_RS04210
uniprot id: A0A8F6DY39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EccB family.
messages: Membrane

39122:KV203 RS09765
gene id: 39122:KV203_RS09765
uniprot id: A0A8F6E4F1
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

39122:KV203 RS10665
gene id: 39122:KV203_RS10665
uniprot id: A0A8F6DTU9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

39122:KV203 RS07300
gene id: 39122:KV203_RS07300
uniprot id: A0A8F6DZ27
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate, the first step in the de novo biosynthesis of NAD(+).
messages: Cytoplasm

39122:KV203 RS09460
gene id: 39122:KV203_RS09460
uniprot id: A0A8F6DZC7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase-binding protein RbpA family.
messages: Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters.
messages: Forms a complex with the RNAP catalytic core and with free principal sigma factors.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

39122:KV203 RS05115
gene id: 39122:KV203_RS05115
uniprot id: A0A8F6HNX0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

39122:KV203 RS14485
gene id: 39122:KV203_RS14485
uniprot id: A0A8F6HN59
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. EgtE subfamily.
messages: Probably catalyzes the conversion of hercynylcysteine sulfoxide to ergothioneine.

39122:KV203 RS04945
gene id: 39122:KV203_RS04945
uniprot id: A0A8F6DY10
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

39122:KV203 RS05345
gene id: 39122:KV203_RS05345
uniprot id: A0A8F6DZA4
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: Could possibly oxidize fatty acids using specific components.

39122:KV203 RS18535
gene id: 39122:KV203_RS18535
uniprot id: A0A8F6HRH9
names: Subcellular Location Annotation
messages: Membrane

39122:KV203 RS16900
gene id: 39122:KV203_RS16900
uniprot id: A0A8F6HP70
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

39122:KV203 RS05035
gene id: 39122:KV203_RS05035
uniprot id: A0A8F6DY20
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

39122:KV203 RS04120
gene id: 39122:KV203_RS04120
uniprot id: A0A8F6E2G2
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

39122:KV203 RS08895
gene id: 39122:KV203_RS08895
uniprot id: A0A8F6DYK3
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

39122:KV203 RS08515
gene id: 39122:KV203_RS08515
uniprot id: A0A8F6DZE8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

39122:KV203 RS09915
gene id: 39122:KV203_RS09915
uniprot id: A0A8F6DXV7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

39122:KV203 RS08650
gene id: 39122:KV203_RS08650
uniprot id: A0A8F6DZ25
names: Similarity
messages: Belongs to the CbbQ/NirQ/NorQ/GpvN family.

39122:KV203 RS04090
gene id: 39122:KV203_RS04090
uniprot id: A0A8F6DX42
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

39122:KV203 RS01365
gene id: 39122:KV203_RS01365
uniprot id: A0A8F6DWT1
names: Subcellular Location Annotation
messages: Membrane

39122:KV203 RS14740
gene id: 39122:KV203_RS14740
uniprot id: A0A8F6HQ34
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatB family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

39122:KV203 RS02620
gene id: 39122:KV203_RS02620
uniprot id: A0A8F6E1M6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

39122:KV203 RS03875
gene id: 39122:KV203_RS03875
uniprot id: A0A8F6DXZ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

39122:KV203 RS01105
gene id: 39122:KV203_RS01105
uniprot id: A0A8F6DX34
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

39122:KV203 RS17470
gene id: 39122:KV203_RS17470
uniprot id: A0A8F6DXW9
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

39122:KV203 RS12470
gene id: 39122:KV203_RS12470
uniprot id: A0A8F6DTR6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

39122:KV203 RS18030
gene id: 39122:KV203_RS18030
uniprot id: A0A8F6HMT3
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

39122:KV203 RS14855
gene id: 39122:KV203_RS14855
uniprot id: A0A8F6DV04
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type 2 tetrahydrodipicolinate N-succinyltransferase family.
messages: Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA.
messages: Cytoplasm
messages: Homotrimer.

39122:KV203 RS17330
gene id: 39122:KV203_RS17330
uniprot id: A0A8F6HNK2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

39122:KV203 RS10115
gene id: 39122:KV203_RS10115
uniprot id: A0A8F6DXQ4
names: Subunit
messages: Heterodimer of an alpha and a beta chain.

39122:KV203 RS12960
gene id: 39122:KV203_RS12960
uniprot id: A0A8F6HM40
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division.

39122:KV203 RS14085
gene id: 39122:KV203_RS14085
uniprot id: A0A8F6DV19
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

39122:KV203 RS06150
gene id: 39122:KV203_RS06150
uniprot id: A0A8F6HQH2
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

39122:KV203 RS05065
gene id: 39122:KV203_RS05065
uniprot id: A0A8F6E2S4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

39122:KV203 RS04410
gene id: 39122:KV203_RS04410
uniprot id: A0A8F6DX81
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

39122:KV203 RS00010
gene id: 39122:KV203_RS00010
uniprot id: A0A8F6HN31
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

39122:KV203 RS04570
gene id: 39122:KV203_RS04570
uniprot id: A0A8F6E2B7
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

39122:KV203 RS14605
gene id: 39122:KV203_RS14605
uniprot id: A0A8F6DZT2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

39122:KV203 RS02190
gene id: 39122:KV203_RS02190
uniprot id: A0A8F6DX33
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

39122:KV203 RS14475
gene id: 39122:KV203_RS14475
uniprot id: A0A8F6HNV0
names: Function
names: Similarity
messages: Belongs to the glutamate--cysteine ligase type 2 family. EgtA subfamily.
messages: Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC). This compound is used as substrate for the biosynthesis of the low-molecular thiol compound ergothioneine.

39122:KV203 RS05845
gene id: 39122:KV203_RS05845
uniprot id: A0A8F6HNY8
names: Similarity
messages: Belongs to the LacAB/RpiB family.

39122:KV203 RS09695
gene id: 39122:KV203_RS09695
uniprot id: A0A8F6HPI6
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
messages: Cytoplasm
messages: The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped by the proteasome-associated ATPase, ARC.
messages: The formation of the proteasomal ATPase ARC-20S proteasome complex, likely via the docking of the C-termini of ARC into the intersubunit pockets in the alpha-rings, may trigger opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity.

39122:KV203 RS14705
gene id: 39122:KV203_RS14705
uniprot id: A0A8F6DW63
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

39122:KV203 RS04355
gene id: 39122:KV203_RS04355
uniprot id: A0A8F6DZY4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cell surface
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
messages: capsule
messages: cell wall

39122:KV203 RS12425
gene id: 39122:KV203_RS12425
uniprot id: A0A8F6DUG1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

39122:KV203 RS18155
gene id: 39122:KV203_RS18155
uniprot id: A0A8F6DW06
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

39122:KV203 RS11155
gene id: 39122:KV203_RS11155
uniprot id: A0A8F6HLN0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

39122:KV203 RS12150
gene id: 39122:KV203_RS12150
uniprot id: A0A8F6HLU1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

39122:KV203 RS18980
gene id: 39122:KV203_RS18980
uniprot id: A0A8F6DW91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

39122:KV203 RS15530
gene id: 39122:KV203_RS15530
uniprot id: A0A8F6HME8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase type 1 family. AlkB subfamily.
messages: Cell inner membrane
messages: Membrane

39122:KV203 RS09065
gene id: 39122:KV203_RS09065
uniprot id: A0A8F6HSG0
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

39122:KV203 RS16170
gene id: 39122:KV203_RS16170
uniprot id: A0A8F6DUV1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

39122:KV203 RS02715
gene id: 39122:KV203_RS02715
uniprot id: A0A8F6DX91
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

39122:KV203 RS01830
gene id: 39122:KV203_RS01830
uniprot id: A0A8F6DWY2
names: Subcellular Location Annotation
messages: Membrane

39122:KV203 RS09125
gene id: 39122:KV203_RS09125
uniprot id: A0A8F6DZM1
names: Subcellular Location Annotation
messages: Membrane

39122:KV203 RS00230
gene id: 39122:KV203_RS00230
uniprot id: A0A8F6HQE3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrgA family.
messages: Cell membrane
messages: Involved in cell division.

39122:KV203 RS04595
gene id: 39122:KV203_RS04595
uniprot id: A0A8F6DXV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

39122:KV203 RS07335
gene id: 39122:KV203_RS07335
uniprot id: A0A8F6E364
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

39122:KV203 RS07270
gene id: 39122:KV203_RS07270
uniprot id: A0A8F6DYR5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

39122:KV203 RS10755
gene id: 39122:KV203_RS10755
uniprot id: A0A8F6DTW1
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

39122:KV203 RS09830
gene id: 39122:KV203_RS09830
uniprot id: A0A8F6DYV2
names: Subcellular Location Annotation
messages: Membrane

39122:KV203 RS18345
gene id: 39122:KV203_RS18345
uniprot id: A0A8F6DW30
names: Similarity
names: Subunit
messages: Belongs to the RNase H family.
messages: Monomer.

39122:KV203 RS17660
gene id: 39122:KV203_RS17660
uniprot id: A0A8F6HQU6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

39122:KV203 RS07005
gene id: 39122:KV203_RS07005
uniprot id: A0A8F6DY00
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

39122:KV203 RS09330
gene id: 39122:KV203_RS09330
uniprot id: A0A8F6HPG7
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

39122:KV203 RS09645
gene id: 39122:KV203_RS09645
uniprot id: A0A8F6DYT2
names: Similarity
messages: Belongs to the peptidase M24B family.

39122:KV203 RS13965
gene id: 39122:KV203_RS13965
uniprot id: A0A8F6DVY6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

39122:KV203 RS19160
gene id: 39122:KV203_RS19160
uniprot id: A0A8F6E182
names: Similarity
messages: In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.
messages: In the central section; belongs to the CRISPR-associated helicase Cas3 family.

39122:KV203 RS11630
gene id: 39122:KV203_RS11630
uniprot id: A0A8F6DTI2
names: Similarity
messages: Belongs to the transglycosylase family. Rpf subfamily.

39122:KV203 RS07185
gene id: 39122:KV203_RS07185
uniprot id: A0A8F6DYM8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
messages: Homotetramer.

39122:KV203 RS02300
gene id: 39122:KV203_RS02300
uniprot id: A0A8F6DXF8
names: Similarity
messages: Belongs to the AAA ATPase family.

39122:KV203 RS11305
gene id: 39122:KV203_RS11305
uniprot id: A0A8F6DVT5
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

39122:KV203 RS00760
gene id: 39122:KV203_RS00760
uniprot id: A0A8F6HR26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

39122:KV203 RS13000
gene id: 39122:KV203_RS13000
uniprot id: A0A8F6DUF8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

39122:KV203 RS09390
gene id: 39122:KV203_RS09390
uniprot id: A0A8F6E4B3
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

39122:KV203 RS05365
gene id: 39122:KV203_RS05365
uniprot id: A0A8F6E056
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

39122:KV203 RS00255
gene id: 39122:KV203_RS00255
uniprot id: A0A8F6DWG8
names: Subcellular Location Annotation
messages: Membrane

39122:KV203 RS17120
gene id: 39122:KV203_RS17120
uniprot id: A0A8F6DWU8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

39122:KV203 RS11880
gene id: 39122:KV203_RS11880
uniprot id: A0A8F6HNF9
names: Subcellular Location Annotation
messages: Membrane

39122:KV203 RS18135
gene id: 39122:KV203_RS18135
uniprot id: A0A8F6HPD2
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

39122:KV203 RS01155
gene id: 39122:KV203_RS01155
uniprot id: A0A8F6E156
names: Function
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: May catalyze the transamination reaction in phenylalanine biosynthesis.

39122:KV203 RS11030
gene id: 39122:KV203_RS11030
uniprot id: A0A8F6DY93
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

39122:KV203 RS07095
gene id: 39122:KV203_RS07095
uniprot id: A0A8F6DYP6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

39122:KV203 RS06080
gene id: 39122:KV203_RS06080
uniprot id: A0A8F6E0Y5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic sulfate-binding protein family.
messages: Periplasm

39122:KV203 RS15365
gene id: 39122:KV203_RS15365
uniprot id: A0A8F6DV68
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

39122:KV203 RS05945
gene id: 39122:KV203_RS05945
uniprot id: A0A8F6DYN4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

39122:KV203 RS19410
gene id: 39122:KV203_RS19410
uniprot id: A0A8F6HQX3
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

39122:KV203 RS04360
gene id: 39122:KV203_RS04360
uniprot id: A0A8F6E2J2
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

39122:KV203 RS06230
gene id: 39122:KV203_RS06230
uniprot id: A0A8F6HQH6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm
messages: Homodimer.

39122:KV203 RS17795
gene id: 39122:KV203_RS17795
uniprot id: A0A8F6DVX0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

39122:KV203 RS05385
gene id: 39122:KV203_RS05385
uniprot id: A0A8F6HQD0
names: Similarity
messages: Belongs to the PrpD family.

39122:KV203 RS07340
gene id: 39122:KV203_RS07340
uniprot id: A0A8F6DYQ5
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

39122:KV203 RS07835
gene id: 39122:KV203_RS07835
uniprot id: A0A8F6DYX7
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

39122:KV203 RS17655
gene id: 39122:KV203_RS17655
uniprot id: A0A8F6E0I5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

39122:KV203 RS17725
gene id: 39122:KV203_RS17725
uniprot id: A0A8F6DVW5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

39122:KV203 RS12730
gene id: 39122:KV203_RS12730
uniprot id: A0A8F6DUB4
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Electron transport system for the ribonucleotide reductase system NrdEF.

39122:KV203 RS09745
gene id: 39122:KV203_RS09745
uniprot id: A0A8F6DZI1
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Feedback inhibited by histidine.

39122:KV203 RS10155
gene id: 39122:KV203_RS10155
uniprot id: A0A8F6DVE5
names: Similarity
messages: Belongs to the band 7/mec-2 family.

39122:KV203 RS03460
gene id: 39122:KV203_RS03460
uniprot id: A0A8F6E284
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

39122:KV203 RS05030
gene id: 39122:KV203_RS05030
uniprot id: A0A8F6DXE9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

39122:KV203 RS17310
gene id: 39122:KV203_RS17310
uniprot id: A0A8F6HMR7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

39122:KV203 RS19060
gene id: 39122:KV203_RS19060
uniprot id: A0A8F6E0N4
names: Similarity
messages: Belongs to the AHA1 family.

39122:KV203 RS18715
gene id: 39122:KV203_RS18715
uniprot id: A0A8F6E130
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

39122:KV203 RS06865
gene id: 39122:KV203_RS06865
uniprot id: A0A8F6HP72
names: Caution
names: PTM
names: Subcellular Location Annotation
names: Subunit
messages: Binds 2 heme c groups covalently per subunit.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The cytochrome bc1 complex is composed of a cytochrome b (QcrB), the Rieske iron-sulfur protein (QcrA) and a diheme cytochrome c (QcrC) subunit.

39122:KV203 RS06775
gene id: 39122:KV203_RS06775
uniprot id: A0A8F6HP36
names: Similarity
messages: Belongs to the asparagine synthetase family.

39122:KV203 RS14445
gene id: 39122:KV203_RS14445
uniprot id: A0A8F6DW33
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

39122:KV203 RS08865
gene id: 39122:KV203_RS08865
uniprot id: A0A8F6HSE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

39122:KV203 RS19110
gene id: 39122:KV203_RS19110
uniprot id: A0A8F6HN12
names: Subcellular Location Annotation
messages: Secreted

39122:KV203 RS12390
gene id: 39122:KV203_RS12390
uniprot id: A0A8F6DUA0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

39122:KV203 RS05360
gene id: 39122:KV203_RS05360
uniprot id: A0A8F6E2U9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

39122:KV203 RS01490
gene id: 39122:KV203_RS01490
uniprot id: A0A8F6DYZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

39122:KV203 RS12180
gene id: 39122:KV203_RS12180
uniprot id: A0A8F6DU56
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

39122:KV203 RS17610
gene id: 39122:KV203_RS17610
uniprot id: A0A8F6E080
names: Function
messages: Catalyzes the reduction of sulfite to sulfide, a step in the biosynthesis of sulfur-containing amino acids and cofactors.

39122:KV203 RS17920
gene id: 39122:KV203_RS17920
uniprot id: A0A8F6DY23
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

39122:KV203 RS03120
gene id: 39122:KV203_RS03120
uniprot id: A0A8F6HNI3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

39122:KV203 RS15590
gene id: 39122:KV203_RS15590
uniprot id: A0A8F6E042
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

39122:KV203 RS06250
gene id: 39122:KV203_RS06250
uniprot id: A0A8F6E2U8
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

39122:KV203 RS15135
gene id: 39122:KV203_RS15135
uniprot id: A0A8F6DV47
names: Similarity
messages: Belongs to the UDPGP type 2 family.

39122:KV203 RS03195
gene id: 39122:KV203_RS03195
uniprot id: A0A8F6HNI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

39122:KV203 RS06710
gene id: 39122:KV203_RS06710
uniprot id: A0A8F6HS24
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

39122:KV203 RS03960
gene id: 39122:KV203_RS03960
uniprot id: A0A8F6E0V1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

39122:KV203 RS09300
gene id: 39122:KV203_RS09300
uniprot id: A0A8F6E0G0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

39122:KV203 RS11835
gene id: 39122:KV203_RS11835
uniprot id: A0A8F6DU27
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

39122:KV203 RS15405
gene id: 39122:KV203_RS15405
uniprot id: A0A8F6E024
names: Similarity
messages: Belongs to the long-chain O-acyltransferase family.

39122:KV203 RS06680
gene id: 39122:KV203_RS06680
uniprot id: A0A8F6E393
names: Subcellular Location Annotation
messages: Membrane

39122:KV203 RS12025
gene id: 39122:KV203_RS12025
uniprot id: A0A8F6DYM0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

39122:KV203 RS19355
gene id: 39122:KV203_RS19355
uniprot id: A0A8F6DXK0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the F420-dependent glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the coenzyme F420-dependent oxidation of glucose 6-phosphate (G6P) to 6-phosphogluconolactone.
messages: Homodimer.

39122:KV203 RS00045
gene id: 39122:KV203_RS00045
uniprot id: A0A8F6DWE9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

39122:KV203 RS16685
gene id: 39122:KV203_RS16685
uniprot id: A0A8F6DWQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

39122:KV203 RS18120
gene id: 39122:KV203_RS18120
uniprot id: A0A8F6DWA6
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

39122:KV203 RS00015
gene id: 39122:KV203_RS00015
uniprot id: A0A8F6HN15
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

39122:KV203 RS11150
gene id: 39122:KV203_RS11150
uniprot id: A0A8F6HLU2
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

39122:KV203 RS13520
gene id: 39122:KV203_RS13520
uniprot id: A0A8F6DUK7
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

39122:KV203 RS13020
gene id: 39122:KV203_RS13020
uniprot id: A0A8F6DVM4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.

39122:KV203 RS09630
gene id: 39122:KV203_RS09630
uniprot id: A0A8F6HQC7
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

39122:KV203 RS12440
gene id: 39122:KV203_RS12440
uniprot id: A0A8F6HNJ0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 2 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

39122:KV203 RS07375
gene id: 39122:KV203_RS07375
uniprot id: A0A8F6E0V2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

39122:KV203 RS02460
gene id: 39122:KV203_RS02460
uniprot id: A0A8F6DZA8
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 independent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.

39122:KV203 RS04250
gene id: 39122:KV203_RS04250
uniprot id: A0A8F6DX61
names: Similarity
messages: Belongs to the WXG100 family.

39122:KV203 RS04315
gene id: 39122:KV203_RS04315
uniprot id: A0A8F6HPK2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.

39122:KV203 RS16070
gene id: 39122:KV203_RS16070
uniprot id: A0A8F6HNE1
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

39122:KV203 RS00170
gene id: 39122:KV203_RS00170
uniprot id: A0A8F6E1D7
names: Caution
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IcmF family.
messages: Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly.
messages: Heterodimer of an alpha and a beta chain.
messages: Homodimer.
messages: Is composed of four functional domains: the N-terminal 5'-deoxyadenosylcobalamin binding region that is homologous to the small subunit of ICM (IcmB), a middle P-loop GTPase domain (MeaI) that likely acts as a chaperone for ICM, a structured linker region involved in dimer formation, and a C-terminal part that is homologous to the large substrate-binding subunit of ICM (IcmA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

39122:KV203 RS13570
gene id: 39122:KV203_RS13570
uniprot id: A0A8F6HM34
names: Similarity
messages: Belongs to the CbbQ/NirQ/NorQ/GpvN family.

39122:KV203 RS10410
gene id: 39122:KV203_RS10410
uniprot id: A0A8F6DUR7
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

39122:KV203 RS04880
gene id: 39122:KV203_RS04880
uniprot id: A0A8F6HNT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

39122:KV203 RS17865
gene id: 39122:KV203_RS17865
uniprot id: A0A8F6HQM3
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

39122:KV203 RS01240
gene id: 39122:KV203_RS01240
uniprot id: A0A8F6HP30
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.
messages: Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

39122:KV203 RS14895
gene id: 39122:KV203_RS14895
uniprot id: A0A8F6DX30
names: Cofactor
names: Function
messages: Binds 1 [3Fe-4S] cluster.
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

39122:KV203 RS14980
gene id: 39122:KV203_RS14980
uniprot id: A0A8F6DX38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 87 family.
messages: Membrane

39122:KV203 RS10015
gene id: 39122:KV203_RS10015
uniprot id: A0A8F6HLG7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

39122:KV203 RS07425
gene id: 39122:KV203_RS07425
uniprot id: A0A8F6DY47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

39122:KV203 RS06105
gene id: 39122:KV203_RS06105
uniprot id: A0A8F6DZI0
names: Function
names: Similarity
messages: Belongs to the Stf0 sulfotransferase family.
messages: Catalyzes the sulfuryl group transfer from 3'-phosphoadenosine-5'-phosphosulfate (PAPS) to trehalose, leading to trehalose-2-sulfate (T2S).

39122:KV203 RS12535
gene id: 39122:KV203_RS12535
uniprot id: A0A8F6HPP4
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: Could possibly oxidize fatty acids using specific components.

39122:KV203 RS12530
gene id: 39122:KV203_RS12530
uniprot id: A0A8F6HNJ4
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

39122:KV203 RS07330
gene id: 39122:KV203_RS07330
uniprot id: A0A8F6HQ04
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

39122:KV203 RS06160
gene id: 39122:KV203_RS06160
uniprot id: A0A8F6HPU8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

39122:KV203 RS04670
gene id: 39122:KV203_RS04670
uniprot id: A0A8F6DZM6
names: Subcellular Location Annotation
messages: Membrane

39122:KV203 RS07515
gene id: 39122:KV203_RS07515
uniprot id: A0A8F6DYS5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IPP isomerase type 1 family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium ion binds only when substrate is bound.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).
messages: Cytoplasm

39122:KV203 RS01725
gene id: 39122:KV203_RS01725
uniprot id: A0A8F6E1C2
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

39122:KV203 RS11235
gene id: 39122:KV203_RS11235
uniprot id: A0A8F6DU19
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.

39122:KV203 RS04270
gene id: 39122:KV203_RS04270
uniprot id: A0A8F6DYZ3
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

39122:KV203 RS05050
gene id: 39122:KV203_RS05050
uniprot id: A0A8F6DZ74
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

39122:KV203 RS11230
gene id: 39122:KV203_RS11230
uniprot id: A0A8F6DYB7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

39122:KV203 RS08640
gene id: 39122:KV203_RS08640
uniprot id: A0A8F6DYH4
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

39122:KV203 RS10525
gene id: 39122:KV203_RS10525
uniprot id: A0A8F6HN90
names: Similarity
messages: Belongs to the Fur family.

39122:KV203 RS06720
gene id: 39122:KV203_RS06720
uniprot id: A0A8F6E2Z8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

39122:KV203 RS02220
gene id: 39122:KV203_RS02220
uniprot id: A0A8F6DXE8
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

39122:KV203 RS03885
gene id: 39122:KV203_RS03885
uniprot id: A0A8F6HNP8
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

39122:KV203 RS08510
gene id: 39122:KV203_RS08510
uniprot id: A0A8F6E3U4
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

39122:KV203 RS18685
gene id: 39122:KV203_RS18685
uniprot id: A0A8F6HNS3
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

39122:KV203 RS08965
gene id: 39122:KV203_RS08965
uniprot id: A0A8F6E3P5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

39122:KV203 RS16980
gene id: 39122:KV203_RS16980
uniprot id: A0A8F6HP75
names: Subcellular Location Annotation
messages: Membrane

39122:KV203 RS11315
gene id: 39122:KV203_RS11315
uniprot id: A0A8F6DU31
names: Similarity
messages: Belongs to the universal stress protein A family.

39122:KV203 RS09580
gene id: 39122:KV203_RS09580
uniprot id: A0A8F6E0J3
names: Similarity
messages: Belongs to the site-specific recombinase resolvase family.

39122:KV203 RS17320
gene id: 39122:KV203_RS17320
uniprot id: A0A8F6HP92
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

39122:KV203 RS03375
gene id: 39122:KV203_RS03375
uniprot id: A0A8F6HQ27
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

39122:KV203 RS19415
gene id: 39122:KV203_RS19415
uniprot id: A0A8F6HNW4
names: Similarity
messages: Belongs to the thioredoxin family.

39122:KV203 RS06715
gene id: 39122:KV203_RS06715
uniprot id: A0A8F6HPX1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

39122:KV203 RS01470
gene id: 39122:KV203_RS01470
uniprot id: A0A8F6DWW0
names: Similarity
messages: Belongs to the CFA/CMAS family.

39122:KV203 RS08940
gene id: 39122:KV203_RS08940
uniprot id: A0A8F6HPE8
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

39122:KV203 RS00655
gene id: 39122:KV203_RS00655
uniprot id: A0A8F6HN62
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.

39122:KV203 RS18050
gene id: 39122:KV203_RS18050
uniprot id: A0A8F6E0C9
names: Similarity
messages: Belongs to the globin family. Two-domain flavohemoproteins subfamily.
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.

39122:KV203 RS15620
gene id: 39122:KV203_RS15620
uniprot id: A0A8F6HMI6
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

39122:KV203 RS14490
gene id: 39122:KV203_RS14490
uniprot id: A0A8F6DZ89
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

39122:KV203 RS09285
gene id: 39122:KV203_RS09285
uniprot id: A0A8F6DZD1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

39122:KV203 RS09375
gene id: 39122:KV203_RS09375
uniprot id: A0A8F6E020
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

39122:KV203 RS04975
gene id: 39122:KV203_RS04975
uniprot id: A0A8F6E045
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

39122:KV203 RS15040
gene id: 39122:KV203_RS15040
uniprot id: A0A8F6DV49
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

39122:KV203 RS01495
gene id: 39122:KV203_RS01495
uniprot id: A0A8F6DZZ1
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

39122:KV203 RS05195
gene id: 39122:KV203_RS05195
uniprot id: A0A8F6HNX5
names: Similarity
messages: Belongs to the peptidase S58 family.

39122:KV203 RS05830
gene id: 39122:KV203_RS05830
uniprot id: A0A8F6E305
names: Similarity
messages: Belongs to the peptidase M1 family.

39122:KV203 RS00405
gene id: 39122:KV203_RS00405
uniprot id: A0A8F6HN33
names: Subcellular Location Annotation
messages: Membrane

39122:KV203 RS16810
gene id: 39122:KV203_RS16810
uniprot id: A0A8F6HP66
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

39122:KV203 RS16415
gene id: 39122:KV203_RS16415
uniprot id: A0A8F6DVI6
names: Domain
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

39122:KV203 RS06215
gene id: 39122:KV203_RS06215
uniprot id: A0A8F6HP08
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

39122:KV203 RS04025
gene id: 39122:KV203_RS04025
uniprot id: A0A8F6DXN7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

39122:KV203 RS03115
gene id: 39122:KV203_RS03115
uniprot id: A0A8F6DXP8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

39122:KV203 RS06195
gene id: 39122:KV203_RS06195
uniprot id: A0A8F6DZJ0
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

39122:KV203 RS01805
gene id: 39122:KV203_RS01805
uniprot id: A0A8F6HPU1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

39122:KV203 RS02815
gene id: 39122:KV203_RS02815
uniprot id: A0A8F6DX94
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyltransferase group 1 family. MshA subfamily.
messages: Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2-acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway.
messages: Homodimer.

39122:KV203 RS06675
gene id: 39122:KV203_RS06675
uniprot id: A0A8F6E0M0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Cytoplasm
messages: Oligomer of 12 subunits arranged in the form of two hexagons.

39122:KV203 RS15315
gene id: 39122:KV203_RS15315
uniprot id: A0A8F6DZS5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

39122:KV203 RS05975
gene id: 39122:KV203_RS05975
uniprot id: A0A8F6HPT8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

39122:KV203 RS11815
gene id: 39122:KV203_RS11815
uniprot id: A0A8F6DYB8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

39122:KV203 RS19270
gene id: 39122:KV203_RS19270
uniprot id: A0A8F6DWP7
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

39122:KV203 RS17215
gene id: 39122:KV203_RS17215
uniprot id: A0A8F6HMR4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

39122:KV203 RS18320
gene id: 39122:KV203_RS18320
uniprot id: A0A8F6HQQ4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

39122:KV203 RS12670
gene id: 39122:KV203_RS12670
uniprot id: A0A8F6DVH9
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

39122:KV203 RS10375
gene id: 39122:KV203_RS10375
uniprot id: A0A8F6DTN0
names: Similarity
messages: Belongs to the FAD-binding monooxygenase family.

39122:KV203 RS00020
gene id: 39122:KV203_RS00020
uniprot id: A0A8F6HPK1
names: Similarity
messages: Belongs to the UPF0232 family.

39122:KV203 RS16750
gene id: 39122:KV203_RS16750
uniprot id: A0A8F6DUZ9
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

39122:KV203 RS09215
gene id: 39122:KV203_RS09215
uniprot id: A0A8F6E1F8
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

39122:KV203 RS11985
gene id: 39122:KV203_RS11985
uniprot id: A0A8F6DYD9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

39122:KV203 RS18130
gene id: 39122:KV203_RS18130
uniprot id: A0A8F6HMT8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

39122:KV203 RS13715
gene id: 39122:KV203_RS13715
uniprot id: A0A8F6DVV8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

39122:KV203 RS06870
gene id: 39122:KV203_RS06870
uniprot id: A0A8F6HQL1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Cell membrane
messages: Iron-sulfur subunit of the cytochrome bc1 complex, an essential component of the respiratory electron transport chain required for ATP synthesis. The bc1 complex catalyzes the oxidation of menaquinol and the reduction of cytochrome c in the respiratory chain. The bc1 complex operates through a Q-cycle mechanism that couples electron transfer to generation of the proton gradient that drives ATP synthesis.
messages: Membrane

39122:KV203 RS01070
gene id: 39122:KV203_RS01070
uniprot id: A0A8F6DWS5
names: Similarity
messages: Belongs to the AHA1 family.

39122:KV203 RS14695
gene id: 39122:KV203_RS14695
uniprot id: A0A8F6DV13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

39122:KV203 RS15455
gene id: 39122:KV203_RS15455
uniprot id: A0A8F6DZK0
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

39122:KV203 RS06100
gene id: 39122:KV203_RS06100
uniprot id: A0A8F6E3A8
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

39122:KV203 RS09230
gene id: 39122:KV203_RS09230
uniprot id: A0A8F6DZM8
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

39122:KV203 RS16430
gene id: 39122:KV203_RS16430
uniprot id: A0A8F6HT16
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

39122:KV203 RS03065
gene id: 39122:KV203_RS03065
uniprot id: A0A8F6E1T1
names: Subcellular Location Annotation
messages: Cell inner membrane

39122:KV203 RS16095
gene id: 39122:KV203_RS16095
uniprot id: A0A8F6DVF8
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.

39122:KV203 RS07295
gene id: 39122:KV203_RS07295
uniprot id: A0A8F6E3G3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

39122:KV203 RS00665
gene id: 39122:KV203_RS00665
uniprot id: A0A8F6HPN3
names: Subcellular Location Annotation
messages: Membrane

39122:KV203 RS12035
gene id: 39122:KV203_RS12035
uniprot id: A0A8F6HLZ0
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

39122:KV203 RS07325
gene id: 39122:KV203_RS07325
uniprot id: A0A8F6HPW3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

39122:KV203 RS06585
gene id: 39122:KV203_RS06585
uniprot id: A0A8F6E3F8
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Phosphotriesterase family.
messages: Binds 2 divalent metal cations per subunit.

39122:KV203 RS12975
gene id: 39122:KV203_RS12975
uniprot id: A0A8F6HPS2
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF2.
messages: Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.

39122:KV203 RS15415
gene id: 39122:KV203_RS15415
uniprot id: A0A8F6DX86
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

39122:KV203 RS12510
gene id: 39122:KV203_RS12510
uniprot id: A0A8F6DUH2
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

39122:KV203 RS12130
gene id: 39122:KV203_RS12130
uniprot id: A0A8F6HRB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

39122:KV203 RS13770
gene id: 39122:KV203_RS13770
uniprot id: A0A8F6DUN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane

39122:KV203 RS11510
gene id: 39122:KV203_RS11510
uniprot id: A0A8F6DYF3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

39122:KV203 RS02355
gene id: 39122:KV203_RS02355
uniprot id: A0A8F6E225
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cell surface
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
messages: capsule
messages: cell wall

39122:KV203 RS15075
gene id: 39122:KV203_RS15075
uniprot id: A0A8F6HMF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arginine deiminase family.
messages: Cytoplasm

39122:KV203 RS04765
gene id: 39122:KV203_RS04765
uniprot id: A0A8F6DXW8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PNT beta subunit family.
messages: Cell inner membrane
messages: Membrane
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

39122:KV203 RS07225
gene id: 39122:KV203_RS07225
uniprot id: A0A8F6HP95
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

39122:KV203 RS05015
gene id: 39122:KV203_RS05015
uniprot id: A0A8F6HPN7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

39122:KV203 RS11545
gene id: 39122:KV203_RS11545
uniprot id: A0A8F6DY88
names: Similarity
messages: Belongs to the PspA/IM30 family.

39122:KV203 RS12885
gene id: 39122:KV203_RS12885
uniprot id: A0A8F6HNL3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial microcompartment
messages: Belongs to the EutB family.
messages: Binds between the large and small subunits.
messages: Catalyzes the deamination of various vicinal amino-alcohols to oxo compounds. Allows this organism to utilize ethanolamine as the sole source of nitrogen and carbon in the presence of vitamin B12.
messages: The basic unit is a heterodimer which dimerizes to form tetramers. The heterotetramers trimerize; 6 large subunits form a core ring with 6 small subunits projecting outwards.

39122:KV203 RS15245
gene id: 39122:KV203_RS15245
uniprot id: A0A8F6DVE8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

39122:KV203 RS07075
gene id: 39122:KV203_RS07075
uniprot id: A0A8F6E338
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SepF family.
messages: Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

39122:KV203 RS12565
gene id: 39122:KV203_RS12565
uniprot id: A0A8F6DTS8
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.

39122:KV203 RS06090
gene id: 39122:KV203_RS06090
uniprot id: A0A8F6DYE3
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

39122:KV203 RS17110
gene id: 39122:KV203_RS17110
uniprot id: A0A8F6DVP7
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

39122:KV203 RS07155
gene id: 39122:KV203_RS07155
uniprot id: A0A8F6HPZ4
names: Subcellular Location Annotation
messages: Cell membrane

39122:KV203 RS02270
gene id: 39122:KV203_RS02270
uniprot id: A0A8F6DX43
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

39122:KV203 RS19465
gene id: 39122:KV203_RS19465
uniprot id: A0A8F6HQ13
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

39122:KV203 RS10475
gene id: 39122:KV203_RS10475
uniprot id: A0A8F6DTL8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

39122:KV203 RS10400
gene id: 39122:KV203_RS10400
uniprot id: A0A8F6HQN2
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

39122:KV203 RS07765
gene id: 39122:KV203_RS07765
uniprot id: A0A8F6DYT5
names: Similarity
messages: Belongs to the long-chain O-acyltransferase family.

39122:KV203 RS18410
gene id: 39122:KV203_RS18410
uniprot id: A0A8F6E0G5
names: Similarity
messages: Belongs to the cytochrome P450 family.

39122:KV203 RS08770
gene id: 39122:KV203_RS08770
uniprot id: A0A8F6HPI5
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

39122:KV203 RS15265
gene id: 39122:KV203_RS15265
uniprot id: A0A8F6HQ65
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

39122:KV203 RS15310
gene id: 39122:KV203_RS15310
uniprot id: A0A8F6DX75
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

39122:KV203 RS10160
gene id: 39122:KV203_RS10160
uniprot id: A0A8F6DXY6
names: Subcellular Location Annotation
messages: Membrane

39122:KV203 RS04955
gene id: 39122:KV203_RS04955
uniprot id: A0A8F6E2X7
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

39122:KV203 RS09105
gene id: 39122:KV203_RS09105
uniprot id: A0A8F6E486
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

39122:KV203 RS19070
gene id: 39122:KV203_RS19070
uniprot id: A0A8F6DVQ2
names: Subcellular Location Annotation
messages: Membrane

39122:KV203 RS07030
gene id: 39122:KV203_RS07030
uniprot id: A0A8F6E0Q7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

39122:KV203 RS11575
gene id: 39122:KV203_RS11575
uniprot id: A0A8F6DV54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

39122:KV203 RS07940
gene id: 39122:KV203_RS07940
uniprot id: A0A8F6DY99
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

39122:KV203 RS11560
gene id: 39122:KV203_RS11560
uniprot id: A0A8F6DU00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

39122:KV203 RS05750
gene id: 39122:KV203_RS05750
uniprot id: A0A8F6E2Z6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

39122:KV203 RS03010
gene id: 39122:KV203_RS03010
uniprot id: A0A8F6DYJ0
names: Subcellular Location Annotation
messages: Membrane

39122:KV203 RS06755
gene id: 39122:KV203_RS06755
uniprot id: A0A8F6DZP3
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

39122:KV203 RS10110
gene id: 39122:KV203_RS10110
uniprot id: A0A8F6HMF8
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

39122:KV203 RS08955
gene id: 39122:KV203_RS08955
uniprot id: A0A8F6HSF4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RuvC family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.

39122:KV203 RS04390
gene id: 39122:KV203_RS04390
uniprot id: A0A8F6HRP5
names: Similarity
messages: Belongs to the IMPDH/GMPR family.

39122:KV203 RS17115
gene id: 39122:KV203_RS17115
uniprot id: A0A8F6E0J1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

39122:KV203 RS06480
gene id: 39122:KV203_RS06480
uniprot id: A0A8F6DYI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF1 family.
messages: Cell membrane

39122:KV203 RS06005
gene id: 39122:KV203_RS06005
uniprot id: A0A8F6DYD1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein L14 (rplN).

39122:KV203 RS01040
gene id: 39122:KV203_RS01040
uniprot id: A0A8F6HR44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

39122:KV203 RS14155
gene id: 39122:KV203_RS14155
uniprot id: A0A8F6DWU6
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

39122:KV203 RS16190
gene id: 39122:KV203_RS16190
uniprot id: A0A8F6DVG2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Could methylate the ribose at the nucleotide 34 wobble position in tRNA.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

39122:KV203 RS06590
gene id: 39122:KV203_RS06590
uniprot id: A0A8F6DZM3
names: Similarity
messages: Belongs to the long-chain O-acyltransferase family.

39122:KV203 RS03880
gene id: 39122:KV203_RS03880
uniprot id: A0A8F6HNM8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

39122:KV203 RS02945
gene id: 39122:KV203_RS02945
uniprot id: A0A8F6HNH3
names: Similarity
messages: Belongs to the CsoR family.

39122:KV203 RS10610
gene id: 39122:KV203_RS10610
uniprot id: A0A8F6HMI7
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

39122:KV203 RS05890
gene id: 39122:KV203_RS05890
uniprot id: A0A8F6DYA1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

39122:KV203 RS16635
gene id: 39122:KV203_RS16635
uniprot id: A0A8F6HNG6
names: Cofactor
names: Similarity
messages: Belongs to the fatty acid desaturase type 2 family.
messages: Binds 2 iron ions per subunit.

39122:KV203 RS05135
gene id: 39122:KV203_RS05135
uniprot id: A0A8F6HPP2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgE subfamily.
messages: Homodimer.
messages: Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1->4)-glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB.

39122:KV203 RS15320
gene id: 39122:KV203_RS15320
uniprot id: A0A8F6DVF7
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

39122:KV203 RS11435
gene id: 39122:KV203_RS11435
uniprot id: A0A8F6HPH1
names: Subcellular Location Annotation
messages: Membrane

39122:KV203 RS08855
gene id: 39122:KV203_RS08855
uniprot id: A0A8F6HPJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

39122:KV203 RS17715
gene id: 39122:KV203_RS17715
uniprot id: A0A8F6DVA4
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.

39122:KV203 RS17190
gene id: 39122:KV203_RS17190
uniprot id: A0A8F6E0K6
names: Similarity
messages: Belongs to the cytochrome P450 family.

39122:KV203 RS12435
gene id: 39122:KV203_RS12435
uniprot id: A0A8F6HLW2
names: Subcellular Location Annotation
messages: Membrane

39122:KV203 RS06550
gene id: 39122:KV203_RS06550
uniprot id: A0A8F6E0Z8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S33 family.
messages: Cytoplasm

39122:KV203 RS18160
gene id: 39122:KV203_RS18160
uniprot id: A0A8F6E4X8
names: Similarity
messages: Belongs to the HSP15 family.

39122:KV203 RS03535
gene id: 39122:KV203_RS03535
uniprot id: A0A8F6E2F7
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

39122:KV203 RS07485
gene id: 39122:KV203_RS07485
uniprot id: A0A8F6HP76
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

39122:KV203 RS08830
gene id: 39122:KV203_RS08830
uniprot id: A0A8F6E1C0
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

39122:KV203 RS02255
gene id: 39122:KV203_RS02255
uniprot id: A0A8F6E1I5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

39122:KV203 RS14465
gene id: 39122:KV203_RS14465
uniprot id: A0A8F6HMC4
names: Function
messages: Catalyzes the hydrolysis of the gamma-glutamyl amide bond of hercynyl-gamma-L-glutamyl-L-cysteine sulfoxide to produce hercynylcysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine.

39122:KV203 RS09235
gene id: 39122:KV203_RS09235
uniprot id: A0A8F6HPG2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

39122:KV203 RS07420
gene id: 39122:KV203_RS07420
uniprot id: A0A8F6DYR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

39122:KV203 RS12005
gene id: 39122:KV203_RS12005
uniprot id: A0A8F6DU57
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

39122:KV203 RS19200
gene id: 39122:KV203_RS19200
uniprot id: A0A8F6HPI7
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

39122:KV203 RS05240
gene id: 39122:KV203_RS05240
uniprot id: A0A8F6DY14
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

39122:KV203 RS03765
gene id: 39122:KV203_RS03765
uniprot id: A0A8F6DX02
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

39122:KV203 RS02925
gene id: 39122:KV203_RS02925
uniprot id: A0A8F6DYH8
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

39122:KV203 RS02675
gene id: 39122:KV203_RS02675
uniprot id: A0A8F6DXJ7
names: Similarity
messages: Belongs to the calycin superfamily. Lipocalin family.

39122:KV203 RS11420
gene id: 39122:KV203_RS11420
uniprot id: A0A8F6HLP7
names: Similarity
messages: Belongs to the FAD-binding monooxygenase family.

39122:KV203 RS06625
gene id: 39122:KV203_RS06625
uniprot id: A0A8F6HQJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

39122:KV203 RS19205
gene id: 39122:KV203_RS19205
uniprot id: A0A8F6HQW0
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

39122:KV203 RS11245
gene id: 39122:KV203_RS11245
uniprot id: A0A8F6HLN6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

39122:KV203 RS09350
gene id: 39122:KV203_RS09350
uniprot id: A0A8F6HQB2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

39122:KV203 RS02075
gene id: 39122:KV203_RS02075
uniprot id: A0A8F6HP73
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the CobB/CobQ family.
messages: Involved in acetate metabolism.
messages: The N-terminal region seems to be important for proper quaternary structure. The C-terminal region contains the substrate-binding site.

39122:KV203 RS08625
gene id: 39122:KV203_RS08625
uniprot id: A0A8F6HQ71
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

39122:KV203 RS17910
gene id: 39122:KV203_RS17910
uniprot id: A0A8F6E0T4
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

39122:KV203 RS01275
gene id: 39122:KV203_RS01275
uniprot id: A0A8F6DZJ5
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

39122:KV203 RS04030
gene id: 39122:KV203_RS04030
uniprot id: A0A8F6E2L7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

39122:KV203 RS00795
gene id: 39122:KV203_RS00795
uniprot id: A0A8F6DWP5
names: Similarity
messages: Belongs to the UDP-galactopyranose/dTDP-fucopyranose mutase family.

39122:KV203 RS17340
gene id: 39122:KV203_RS17340
uniprot id: A0A8F6DVS5
names: Similarity
messages: Belongs to the extradiol ring-cleavage dioxygenase family.

39122:KV203 RS16100
gene id: 39122:KV203_RS16100
uniprot id: A0A8F6DVF6
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

39122:KV203 RS12410
gene id: 39122:KV203_RS12410
uniprot id: A0A8F6DYR2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

39122:KV203 RS02265
gene id: 39122:KV203_RS02265
uniprot id: A0A8F6DWI1
names: Subcellular Location Annotation
messages: Membrane

39122:KV203 RS01820
gene id: 39122:KV203_RS01820
uniprot id: A0A8F6HP59
names: Similarity
messages: Belongs to the GSP E family.

39122:KV203 RS13975
gene id: 39122:KV203_RS13975
uniprot id: A0A8F6DZB5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. DeaD/CsdA subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation.

39122:KV203 RS12460
gene id: 39122:KV203_RS12460
uniprot id: A0A8F6DYI9
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

39122:KV203 RS04965
gene id: 39122:KV203_RS04965
uniprot id: A0A8F6DZ66
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

39122:KV203 RS14970
gene id: 39122:KV203_RS14970
uniprot id: A0A8F6DZW9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

39122:KV203 RS07440
gene id: 39122:KV203_RS07440
uniprot id: A0A8F6HQK3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

39122:KV203 RS04825
gene id: 39122:KV203_RS04825
uniprot id: A0A8F6E2E7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

39122:KV203 RS07265
gene id: 39122:KV203_RS07265
uniprot id: A0A8F6DY32
names: Function
messages: TetR is the repressor of the tetracycline resistance element; its N-terminal region forms a helix-turn-helix structure and binds DNA. Binding of tetracycline to TetR reduces the repressor affinity for the tetracycline resistance gene (tetA) promoter operator sites.

39122:KV203 RS16400
gene id: 39122:KV203_RS16400
uniprot id: A0A8F6DZV3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

39122:KV203 RS14955
gene id: 39122:KV203_RS14955
uniprot id: A0A8F6DUI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

39122:KV203 RS09980
gene id: 39122:KV203_RS09980
uniprot id: A0A8F6DYB3
names: Similarity
messages: Belongs to the phosphoribulokinase family.

39122:KV203 RS03360
gene id: 39122:KV203_RS03360
uniprot id: A0A8F6HNL9
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.

39122:KV203 RS10450
gene id: 39122:KV203_RS10450
uniprot id: A0A8F6HMH8
names: Function
names: Similarity
messages: Belongs to the WhiA family.
messages: Involved in cell division and chromosome segregation.

39122:KV203 RS04455
gene id: 39122:KV203_RS04455
uniprot id: A0A8F6HNR0
names: Similarity
messages: Belongs to the FAD-binding monooxygenase family.

39122:KV203 RS10000
gene id: 39122:KV203_RS10000
uniprot id: A0A8F6DTL3
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the RuBisCO large chain family. Type I subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterohexadecamer of 8 large chains and 8 small chains.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site.
messages: The basic functional RuBisCO is composed of a large chain homodimer in a 'head-to-tail' conformation. In form I RuBisCO this homodimer is arranged in a barrel-like tetramer with the small subunits forming a tetrameric 'cap' on each end of the 'barrel'.

39122:KV203 RS05210
gene id: 39122:KV203_RS05210
uniprot id: A0A8F6HRU1
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

39122:KV203 RS03675
gene id: 39122:KV203_RS03675
uniprot id: A0A8F6DXK5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

39122:KV203 RS14755
gene id: 39122:KV203_RS14755
uniprot id: A0A8F6DZC3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

39122:KV203 RS01440
gene id: 39122:KV203_RS01440
uniprot id: A0A8F6HP39
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

39122:KV203 RS12955
gene id: 39122:KV203_RS12955
uniprot id: A0A8F6DUM8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in cellular division.

39122:KV203 RS15810
gene id: 39122:KV203_RS15810
uniprot id: A0A8F6DZP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

39122:KV203 RS10695
gene id: 39122:KV203_RS10695
uniprot id: A0A8F6DXY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

39122:KV203 RS10265
gene id: 39122:KV203_RS10265
uniprot id: A0A8F6HP98
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

39122:KV203 RS12590
gene id: 39122:KV203_RS12590
uniprot id: A0A8F6DW98
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ETF beta-subunit/FixA family.
messages: Heterodimer of an alpha and a beta subunit.
messages: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

39122:KV203 RS07050
gene id: 39122:KV203_RS07050
uniprot id: A0A8F6DZR6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

39122:KV203 RS04160
gene id: 39122:KV203_RS04160
uniprot id: A0A8F6HPJ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

39122:KV203 RS13085
gene id: 39122:KV203_RS13085
uniprot id: A0A8F6DUF5
names: Similarity
messages: Belongs to the peptidase S16 family.

39122:KV203 RS05215
gene id: 39122:KV203_RS05215
uniprot id: A0A8F6HPP7
names: Subcellular Location Annotation
messages: Membrane

39122:KV203 RS10560
gene id: 39122:KV203_RS10560
uniprot id: A0A8F6DTM8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NRAMP family.
messages: Cell membrane
messages: H(+)-stimulated, divalent metal cation uptake system.

39122:KV203 RS09190
gene id: 39122:KV203_RS09190
uniprot id: A0A8F6HPY4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Monomer.

39122:KV203 RS05265
gene id: 39122:KV203_RS05265
uniprot id: A0A8F6E072
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

39122:KV203 RS09985
gene id: 39122:KV203_RS09985
uniprot id: A0A8F6DUM0
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

39122:KV203 RS01795
gene id: 39122:KV203_RS01795
uniprot id: A0A8F6HNB4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

39122:KV203 RS14900
gene id: 39122:KV203_RS14900
uniprot id: A0A8F6E0P2
names: Function
names: Similarity
messages: Catalyzes the radical-mediated synthesis of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (FO) from 5-amino-6-(D-ribitylamino)uracil and L-tyrosine.
messages: In the C-terminal section; belongs to the radical SAM superfamily. CofH family.
messages: In the N-terminal section; belongs to the radical SAM superfamily. CofG family.

39122:KV203 RS03690
gene id: 39122:KV203_RS03690
uniprot id: A0A8F6DXK1
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

39122:KV203 RS02045
gene id: 39122:KV203_RS02045
uniprot id: A0A8F6E1Q6
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

39122:KV203 RS01780
gene id: 39122:KV203_RS01780
uniprot id: A0A8F6E1M2
names: Subcellular Location Annotation
messages: Membrane

39122:KV203 RS04605
gene id: 39122:KV203_RS04605
uniprot id: A0A8F6DZ33
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

39122:KV203 RS17905
gene id: 39122:KV203_RS17905
uniprot id: A0A8F6DVY5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

39122:KV203 RS02450
gene id: 39122:KV203_RS02450
uniprot id: A0A8F6E235
names: Cofactor
messages: Can also use Mn(2+) ion.

39122:KV203 RS07190
gene id: 39122:KV203_RS07190
uniprot id: A0A8F6E3M7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 13 family.
messages: Cytoplasm

39122:KV203 RS00395
gene id: 39122:KV203_RS00395
uniprot id: A0A8F6DWV5
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

39122:KV203 RS16135
gene id: 39122:KV203_RS16135
uniprot id: A0A8F6HML4
names: Similarity
messages: Belongs to the ribonuclease N1/T1 family.

39122:KV203 RS12935
gene id: 39122:KV203_RS12935
uniprot id: A0A8F6DVL6
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

39122:KV203 RS03830
gene id: 39122:KV203_RS03830
uniprot id: A0A8F6E229
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

39122:KV203 RS18905
gene id: 39122:KV203_RS18905
uniprot id: A0A8F6E151
names: Similarity
messages: Belongs to the DyP-type peroxidase family.

39122:KV203 RS15595
gene id: 39122:KV203_RS15595
uniprot id: A0A8F6DWF2
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

39122:KV203 RS18665
gene id: 39122:KV203_RS18665
uniprot id: A0A8F6HMW8
names: Similarity
messages: Belongs to the isochorismate synthase family.

39122:KV203 RS11145
gene id: 39122:KV203_RS11145
uniprot id: A0A8F6DU07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

39122:KV203 RS17125
gene id: 39122:KV203_RS17125
uniprot id: A0A8F6DXR8
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

39122:KV203 RS10230
gene id: 39122:KV203_RS10230
uniprot id: A0A8F6DUP9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.

39122:KV203 RS08055
gene id: 39122:KV203_RS08055
uniprot id: A0A8F6E128
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

39122:KV203 RS03345
gene id: 39122:KV203_RS03345
uniprot id: A0A8F6DXT4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TPP enzyme family. MenD subfamily.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
messages: Homodimer.

39122:KV203 RS15300
gene id: 39122:KV203_RS15300
uniprot id: A0A8F6E006
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

39122:KV203 RS08150
gene id: 39122:KV203_RS08150
uniprot id: A0A8F6HR82
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

39122:KV203 RS06500
gene id: 39122:KV203_RS06500
uniprot id: A0A8F6E0K1
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

39122:KV203 RS00005
gene id: 39122:KV203_RS00005
uniprot id: A0A8F6DWR7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

39122:KV203 RS14030
gene id: 39122:KV203_RS14030
uniprot id: A0A8F6HN34
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

39122:KV203 RS02985
gene id: 39122:KV203_RS02985
uniprot id: A0A8F6DWQ8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

39122:KV203 RS00285
gene id: 39122:KV203_RS00285
uniprot id: A0A8F6E163
names: Similarity
messages: Belongs to the glutamate synthase family.

39122:KV203 RS02080
gene id: 39122:KV203_RS02080
uniprot id: A0A8F6E1G4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

39122:KV203 RS18405
gene id: 39122:KV203_RS18405
uniprot id: A0A8F6HNQ8
names: Similarity
messages: Belongs to the long-chain O-acyltransferase family.

39122:KV203 RS08260
gene id: 39122:KV203_RS08260
uniprot id: A0A8F6HPF5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

39122:KV203 RS13655
gene id: 39122:KV203_RS13655
uniprot id: A0A8F6DUX4
names: Similarity
messages: Belongs to the cytochrome P450 family.

39122:KV203 RS06725
gene id: 39122:KV203_RS06725
uniprot id: A0A8F6DYI6
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

39122:KV203 RS12205
gene id: 39122:KV203_RS12205
uniprot id: A0A8F6E029
names: Similarity
messages: Belongs to the P(II) protein family.

39122:KV203 RS19460
gene id: 39122:KV203_RS19460
uniprot id: A0A8F6DYK0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

39122:KV203 RS08820
gene id: 39122:KV203_RS08820
uniprot id: A0A8F6E455
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

39122:KV203 RS11720
gene id: 39122:KV203_RS11720
uniprot id: A0A8F6HMP5
names: Similarity
messages: Belongs to the ribF family.

39122:KV203 RS08945
gene id: 39122:KV203_RS08945
uniprot id: A0A8F6HPJ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glutaminase PdxT/SNO family.
messages: Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
messages: In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer.

39122:KV203 RS10565
gene id: 39122:KV203_RS10565
uniprot id: A0A8F6DYI0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

39122:KV203 RS11885
gene id: 39122:KV203_RS11885
uniprot id: A0A8F6HPJ9
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

39122:KV203 RS18075
gene id: 39122:KV203_RS18075
uniprot id: A0A8F6DVE6
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

39122:KV203 RS12345
gene id: 39122:KV203_RS12345
uniprot id: A0A8F6HMT6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

39122:KV203 RS08130
gene id: 39122:KV203_RS08130
uniprot id: A0A8F6DYX3
names: Subcellular Location Annotation
messages: Membrane

39122:KV203 RS11390
gene id: 39122:KV203_RS11390
uniprot id: A0A8F6DV34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

39122:KV203 RS17450
gene id: 39122:KV203_RS17450
uniprot id: A0A8F6DVT7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

39122:KV203 RS15940
gene id: 39122:KV203_RS15940
uniprot id: A0A8F6DWJ2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

39122:KV203 RS00190
gene id: 39122:KV203_RS00190
uniprot id: A0A8F6DWT8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

39122:KV203 RS12215
gene id: 39122:KV203_RS12215
uniprot id: A0A8F6DW50
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

39122:KV203 RS18945
gene id: 39122:KV203_RS18945
uniprot id: A0A8F6HQU4
names: Similarity
messages: Belongs to the lysine N(6)-hydroxylase/L-ornithine N(5)-oxygenase family.

39122:KV203 RS14310
gene id: 39122:KV203_RS14310
uniprot id: A0A8F6DUU6
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

39122:KV203 RS05145
gene id: 39122:KV203_RS05145
uniprot id: A0A8F6DY21
names: Function
names: Similarity
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

39122:KV203 RS12310
gene id: 39122:KV203_RS12310
uniprot id: A0A8F6DW61
names: Function
messages: Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.

39122:KV203 RS12385
gene id: 39122:KV203_RS12385
uniprot id: A0A8F6DU86
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

39122:KV203 RS08950
gene id: 39122:KV203_RS08950
uniprot id: A0A8F6HQW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

39122:KV203 RS16805
gene id: 39122:KV203_RS16805
uniprot id: A0A8F6HML5
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

39122:KV203 RS09710
gene id: 39122:KV203_RS09710
uniprot id: A0A8F6HR03
names: Similarity
messages: Belongs to the Pup ligase/Pup deamidase family. Pup deamidase subfamily.

39122:KV203 RS10125
gene id: 39122:KV203_RS10125
uniprot id: A0A8F6DT18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Membrane

39122:KV203 RS04000
gene id: 39122:KV203_RS04000
uniprot id: A0A8F6HPI4
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

39122:KV203 RS06040
gene id: 39122:KV203_RS06040
uniprot id: A0A8F6HNZ8
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

39122:KV203 RS05880
gene id: 39122:KV203_RS05880
uniprot id: A0A8F6E2Q9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

39122:KV203 RS12365
gene id: 39122:KV203_RS12365
uniprot id: A0A8F6DU78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

39122:KV203 RS04065
gene id: 39122:KV203_RS04065
uniprot id: A0A8F6HQ63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

39122:KV203 RS07080
gene id: 39122:KV203_RS07080
uniprot id: A0A8F6DYM3
names: Similarity
messages: Belongs to the YggT family.

39122:KV203 RS11940
gene id: 39122:KV203_RS11940
uniprot id: A0A8F6DV96
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

39122:KV203 RS04110
gene id: 39122:KV203_RS04110
uniprot id: A0A8F6DYX6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

39122:KV203 RS17280
gene id: 39122:KV203_RS17280
uniprot id: A0A8F6E0L7
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

39122:KV203 RS11830
gene id: 39122:KV203_RS11830
uniprot id: A0A8F6DTJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

39122:KV203 RS17730
gene id: 39122:KV203_RS17730
uniprot id: A0A8F6DZT1
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

39122:KV203 RS14500
gene id: 39122:KV203_RS14500
uniprot id: A0A8F6DUW6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

39122:KV203 RS14735
gene id: 39122:KV203_RS14735
uniprot id: A0A8F6HNW3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.
messages: In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: In the N-terminal section; belongs to the MIP18 family.

39122:KV203 RS06780
gene id: 39122:KV203_RS06780
uniprot id: A0A8F6HPV8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Membrane
messages: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).

39122:KV203 RS07035
gene id: 39122:KV203_RS07035
uniprot id: A0A8F6E3D3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

39122:KV203 RS16180
gene id: 39122:KV203_RS16180
uniprot id: A0A8F6HQ56
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

39122:KV203 RS15780
gene id: 39122:KV203_RS15780
uniprot id: A0A8F6DVK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

39122:KV203 RS16410
gene id: 39122:KV203_RS16410
uniprot id: A0A8F6DUX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPAT/DAPAT family.
messages: Cell membrane
messages: Membrane

39122:KV203 RS04690
gene id: 39122:KV203_RS04690
uniprot id: A0A8F6DZ41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

39122:KV203 RS09665
gene id: 39122:KV203_RS09665
uniprot id: A0A8F6E4E1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

39122:KV203 RS03415
gene id: 39122:KV203_RS03415
uniprot id: A0A8F6DXH5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

39122:KV203 RS12795
gene id: 39122:KV203_RS12795
uniprot id: A0A8F6HPR0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

39122:KV203 RS04575
gene id: 39122:KV203_RS04575
uniprot id: A0A8F6DXW1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

39122:KV203 RS09130
gene id: 39122:KV203_RS09130
uniprot id: A0A8F6HPF7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.

39122:KV203 RS16695
gene id: 39122:KV203_RS16695
uniprot id: A0A8F6E068
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

39122:KV203 RS06895
gene id: 39122:KV203_RS06895
uniprot id: A0A8F6DXZ0
names: Similarity
messages: Belongs to the class-II DAHP synthase family.

39122:KV203 RS11225
gene id: 39122:KV203_RS11225
uniprot id: A0A8F6DVS4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

39122:KV203 RS04135
gene id: 39122:KV203_RS04135
uniprot id: A0A8F6HNP2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

39122:KV203 RS09325
gene id: 39122:KV203_RS09325
uniprot id: A0A8F6DZN9
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

39122:KV203 RS10825
gene id: 39122:KV203_RS10825
uniprot id: A0A8F6E0G1
names: Similarity
messages: Belongs to the cytochrome P450 family.

39122:KV203 RS09615
gene id: 39122:KV203_RS09615
uniprot id: A0A8F6HQZ9
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

39122:KV203 RS06785
gene id: 39122:KV203_RS06785
uniprot id: A0A8F6HP67
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with subunits I, II and III to form cytochrome c oxidase.
messages: Belongs to the cytochrome c oxidase bacterial subunit CtaF family.
messages: Cell membrane
messages: Membrane
messages: Part of cytochrome c oxidase, its function is unknown.

39122:KV203 RS04035
gene id: 39122:KV203_RS04035
uniprot id: A0A8F6DYW8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

39122:KV203 RS14540
gene id: 39122:KV203_RS14540
uniprot id: A0A8F6DZH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

39122:KV203 RS05895
gene id: 39122:KV203_RS05895
uniprot id: A0A8F6DXP2
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

39122:KV203 RS08395
gene id: 39122:KV203_RS08395
uniprot id: A0A8F6DZ37
names: Similarity
messages: Belongs to the cytochrome P450 family.

39122:KV203 RS12275
gene id: 39122:KV203_RS12275
uniprot id: A0A8F6DU66
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

39122:KV203 RS10305
gene id: 39122:KV203_RS10305
uniprot id: A0A8F6DUR0
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

39122:KV203 RS10480
gene id: 39122:KV203_RS10480
uniprot id: A0A8F6DYG8
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.

39122:KV203 RS17020
gene id: 39122:KV203_RS17020
uniprot id: A0A8F6DVN8
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

39122:KV203 RS04560
gene id: 39122:KV203_RS04560
uniprot id: A0A8F6HRQ5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

39122:KV203 RS14090
gene id: 39122:KV203_RS14090
uniprot id: A0A8F6HMA6
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

39122:KV203 RS14070
gene id: 39122:KV203_RS14070
uniprot id: A0A8F6DVZ4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

39122:KV203 RS11440
gene id: 39122:KV203_RS11440
uniprot id: A0A8F6HMM9
names: Subcellular Location Annotation
messages: Membrane

39122:KV203 RS05885
gene id: 39122:KV203_RS05885
uniprot id: A0A8F6HSQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

39122:KV203 RS18240
gene id: 39122:KV203_RS18240
uniprot id: A0A8F6E0E6
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

39122:KV203 RS12515
gene id: 39122:KV203_RS12515
uniprot id: A0A8F6HM17
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

39122:KV203 RS00365
gene id: 39122:KV203_RS00365
uniprot id: A0A8F6DWH8
names: Subcellular Location Annotation
messages: Membrane

39122:KV203 RS18730
gene id: 39122:KV203_RS18730
uniprot id: A0A8F6E0E8
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

39122:KV203 RS12080
gene id: 39122:KV203_RS12080
uniprot id: A0A8F6DU55
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

39122:KV203 RS09290
gene id: 39122:KV203_RS09290
uniprot id: A0A8F6DZ96
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

39122:KV203 RS07755
gene id: 39122:KV203_RS07755
uniprot id: A0A8F6DZZ3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

39122:KV203 RS01650
gene id: 39122:KV203_RS01650
uniprot id: A0A8F6DWX8
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids lysine, threonine, isoleucine and methionine.

39122:KV203 RS03570
gene id: 39122:KV203_RS03570
uniprot id: A0A8F6HNM9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

39122:KV203 RS10350
gene id: 39122:KV203_RS10350
uniprot id: A0A8F6HPA4
names: Similarity
messages: Belongs to the cytochrome P450 family.

39122:KV203 RS05840
gene id: 39122:KV203_RS05840
uniprot id: A0A8F6DYM4
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

39122:KV203 RS12135
gene id: 39122:KV203_RS12135
uniprot id: A0A8F6HLZ6
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

39122:KV203 RS17195
gene id: 39122:KV203_RS17195
uniprot id: A0A8F6DWV9
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

39122:KV203 RS16165
gene id: 39122:KV203_RS16165
uniprot id: A0A8F6DVG0
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

39122:KV203 RS17880
gene id: 39122:KV203_RS17880
uniprot id: A0A8F6DVX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

39122:KV203 RS18790
gene id: 39122:KV203_RS18790
uniprot id: A0A8F6E0D7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

39122:KV203 RS19125
gene id: 39122:KV203_RS19125
uniprot id: A0A8F6HQV5
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

39122:KV203 RS13685
gene id: 39122:KV203_RS13685
uniprot id: A0A8F6DZ03
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: Could possibly oxidize fatty acids using specific components.

39122:KV203 RS09995
gene id: 39122:KV203_RS09995
uniprot id: A0A8F6DXW6
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the RuBisCO small chain family.
messages: Heterohexadecamer of 8 large and 8 small subunits.
messages: RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site. Although the small subunit is not catalytic it is essential for maximal activity.
messages: The basic functional RuBisCO is composed of a large chain homodimer in a 'head-to-tail' conformation. In form I RuBisCO this homodimer is arranged in a barrel-like tetramer with the small subunits forming a tetrameric 'cap' on each end of the 'barrel'.

39122:KV203 RS04225
gene id: 39122:KV203_RS04225
uniprot id: A0A8F6HQ73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S8 family.
messages: Cell membrane
messages: Membrane

39122:KV203 RS03160
gene id: 39122:KV203_RS03160
uniprot id: A0A8F6DXE4
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

39122:KV203 RS10800
gene id: 39122:KV203_RS10800
uniprot id: A0A8F6HMJ7
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

39122:KV203 RS18000
gene id: 39122:KV203_RS18000
uniprot id: A0A8F6E0V0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM86 family.
messages: Membrane

39122:KV203 RS09260
gene id: 39122:KV203_RS09260
uniprot id: A0A8F6E3T0
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

39122:KV203 RS02250
gene id: 39122:KV203_RS02250
uniprot id: A0A8F6HP84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

39122:KV203 RS12240
gene id: 39122:KV203_RS12240
uniprot id: A0A8F6HM00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0719 family.
messages: Membrane

39122:KV203 RS09265
gene id: 39122:KV203_RS09265
uniprot id: A0A8F6HQM2
names: Similarity
messages: Belongs to the OMP decarboxylase family. Type 2 subfamily.

39122:KV203 RS10445
gene id: 39122:KV203_RS10445
uniprot id: A0A8F6HPB0
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

39122:KV203 RS17890
gene id: 39122:KV203_RS17890
uniprot id: A0A8F6DVC5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

39122:KV203 RS04125
gene id: 39122:KV203_RS04125
uniprot id: A0A8F6E032
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

39122:KV203 RS08540
gene id: 39122:KV203_RS08540
uniprot id: A0A8F6HQ67
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

39122:KV203 RS15610
gene id: 39122:KV203_RS15610
uniprot id: A0A8F6DZV5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

39122:KV203 RS04675
gene id: 39122:KV203_RS04675
uniprot id: A0A8F6DXY2
names: Subcellular Location Annotation
messages: Cytoplasm

39122:KV203 RS02165
gene id: 39122:KV203_RS02165
uniprot id: A0A8F6HP78
names: Function
messages: Catalyzes the phosphorylation of hydroxymethylpyrimidine phosphate (HMP-P) to HMP-PP, and of HMP to HMP-P.

39122:KV203 RS12875
gene id: 39122:KV203_RS12875
uniprot id: A0A8F6HLY9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

39122:KV203 RS07065
gene id: 39122:KV203_RS07065
uniprot id: A0A8F6HS45
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

39122:KV203 RS11480
gene id: 39122:KV203_RS11480
uniprot id: A0A8F6DTY5
names: Similarity
names: Subunit
messages: Belongs to the pyruvate kinase family.
messages: Homotetramer.

39122:KV203 RS12785
gene id: 39122:KV203_RS12785
uniprot id: A0A8F6HLY3
names: Similarity
messages: Belongs to the fructosamine kinase family.

39122:KV203 RS16395
gene id: 39122:KV203_RS16395
uniprot id: A0A8F6HNF3
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

39122:KV203 RS11570
gene id: 39122:KV203_RS11570
uniprot id: A0A8F6DYU1
names: Similarity
messages: Belongs to the YciI family.

39122:KV203 RS08845
gene id: 39122:KV203_RS08845
uniprot id: A0A8F6HPE4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

39122:KV203 RS07360
gene id: 39122:KV203_RS07360
uniprot id: A0A8F6HR72
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

39122:KV203 RS12600
gene id: 39122:KV203_RS12600
uniprot id: A0A8F6DUI2
names: Similarity
messages: Belongs to the glycosyl hydrolase 57 family.

39122:KV203 RS18590
gene id: 39122:KV203_RS18590
uniprot id: A0A8F6HQS1
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

39122:KV203 RS16825
gene id: 39122:KV203_RS16825
uniprot id: A0A8F6DZY6
names: Similarity
messages: Belongs to the long-chain O-acyltransferase family.

39122:KV203 RS06575
gene id: 39122:KV203_RS06575
uniprot id: A0A8F6DYJ2
names: Similarity
messages: Belongs to the glutamine synthetase family.

39122:KV203 RS17815
gene id: 39122:KV203_RS17815
uniprot id: A0A8F6E0S3
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

39122:KV203 RS03475
gene id: 39122:KV203_RS03475
uniprot id: A0A8F6DXU4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

39122:KV203 RS01585
gene id: 39122:KV203_RS01585
uniprot id: A0A8F6E1K3
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.

39122:KV203 RS06200
gene id: 39122:KV203_RS06200
uniprot id: A0A8F6E0H1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

39122:KV203 RS08735
gene id: 39122:KV203_RS08735
uniprot id: A0A8F6E449
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.