388950:A0W33 RS12195
gene id: 388950:A0W33_RS12195
uniprot id: A0A1I7J912
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

388950:A0W33 RS06300
gene id: 388950:A0W33_RS06300
uniprot id: A0A1I7IKF4
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

388950:A0W33 RS05390
gene id: 388950:A0W33_RS05390
uniprot id: A0A1I7K8D3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

388950:A0W33 RS11160
gene id: 388950:A0W33_RS11160
uniprot id: A0A1I7JFA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

388950:A0W33 RS04000
gene id: 388950:A0W33_RS04000
uniprot id: A0A1I7JZA7
names: Similarity
messages: Belongs to the SusD family.

388950:A0W33 RS03735
gene id: 388950:A0W33_RS03735
uniprot id: A0A1I7JY46
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

388950:A0W33 RS05050
gene id: 388950:A0W33_RS05050
uniprot id: A0A1I7K5W6
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

388950:A0W33 RS16115
gene id: 388950:A0W33_RS16115
uniprot id: A0A1I7KSD4
names: Similarity
messages: Belongs to the AHA1 family.

388950:A0W33 RS03885
gene id: 388950:A0W33_RS03885
uniprot id: A0A1I7JYS2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

388950:A0W33 RS14155
gene id: 388950:A0W33_RS14155
uniprot id: A0A1I7KV29
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

388950:A0W33 RS08030
gene id: 388950:A0W33_RS08030
uniprot id: A0A1I7I515
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

388950:A0W33 RS19430
gene id: 388950:A0W33_RS19430
uniprot id: A0A1I7G7M0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

388950:A0W33 RS01830
gene id: 388950:A0W33_RS01830
uniprot id: A0A1I7GTY2
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

388950:A0W33 RS13090
gene id: 388950:A0W33_RS13090
uniprot id: A0A1I7J220
names: Subcellular Location Annotation
messages: Membrane

388950:A0W33 RS09455
gene id: 388950:A0W33_RS09455
uniprot id: A0A1I7HS16
names: Subcellular Location Annotation
messages: Membrane

388950:A0W33 RS03965
gene id: 388950:A0W33_RS03965
uniprot id: A0A1I7JZA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Membrane

388950:A0W33 RS02460
gene id: 388950:A0W33_RS02460
uniprot id: A0A1I7H080
names: Similarity
messages: Belongs to the universal stress protein A family.

388950:A0W33 RS16190
gene id: 388950:A0W33_RS16190
uniprot id: A0A1I7FE72
names: Subcellular Location Annotation
messages: Membrane

388950:A0W33 RS17575
gene id: 388950:A0W33_RS17575
uniprot id: A0A1I7FRW4
names: Function
names: Similarity
messages: Belongs to the RlpA family.
messages: Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.

388950:A0W33 RS03020
gene id: 388950:A0W33_RS03020
uniprot id: A0A1I7H4Z2
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

388950:A0W33 RS10550
gene id: 388950:A0W33_RS10550
uniprot id: A0A1I7JIZ7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

388950:A0W33 RS19885
gene id: 388950:A0W33_RS19885
uniprot id: A0A1I7GB45
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

388950:A0W33 RS19070
gene id: 388950:A0W33_RS19070
uniprot id: A0A1I7G5D7
names: Subcellular Location Annotation
messages: Membrane

388950:A0W33 RS15080
gene id: 388950:A0W33_RS15080
uniprot id: A0A1I7KGJ9
names: Subcellular Location Annotation
messages: Membrane

388950:A0W33 RS07075
gene id: 388950:A0W33_RS07075
uniprot id: A0A1I7IDB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

388950:A0W33 RS05100
gene id: 388950:A0W33_RS05100
uniprot id: A0A1I7K6I3
names: Subcellular Location Annotation
messages: Membrane

388950:A0W33 RS05065
gene id: 388950:A0W33_RS05065
uniprot id: A0A1I7K640
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

388950:A0W33 RS13555
gene id: 388950:A0W33_RS13555
uniprot id: A0A1I7KM55
names: Cofactor
names: Similarity
messages: Belongs to the arginase family.
messages: Binds 2 manganese ions per subunit.

388950:A0W33 RS16260
gene id: 388950:A0W33_RS16260
uniprot id: A0A1I7FEW4
names: Similarity
messages: Belongs to the GbsR family.

388950:A0W33 RS02205
gene id: 388950:A0W33_RS02205
uniprot id: A0A1I7GXQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

388950:A0W33 RS18265
gene id: 388950:A0W33_RS18265
uniprot id: A0A1I7FY43
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

388950:A0W33 RS05880
gene id: 388950:A0W33_RS05880
uniprot id: A0A1I7KAB2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

388950:A0W33 RS13035
gene id: 388950:A0W33_RS13035
uniprot id: A0A1I7J2C6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

388950:A0W33 RS05570
gene id: 388950:A0W33_RS05570
uniprot id: A0A1I7K968
names: Similarity
messages: Belongs to the peptidase S66 family.

388950:A0W33 RS02245
gene id: 388950:A0W33_RS02245
uniprot id: A0A1I7GY47
names: Subcellular Location Annotation
messages: Membrane

388950:A0W33 RS12010
gene id: 388950:A0W33_RS12010
uniprot id: A0A1I7JA36
names: Similarity
messages: Belongs to the UPF0162 family.

388950:A0W33 RS09020
gene id: 388950:A0W33_RS09020
uniprot id: A0A1I7HWX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

388950:A0W33 RS17730
gene id: 388950:A0W33_RS17730
uniprot id: A0A1I7FT13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

388950:A0W33 RS00765
gene id: 388950:A0W33_RS00765
uniprot id: A0A1I7GJ09
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

388950:A0W33 RS10090
gene id: 388950:A0W33_RS10090
uniprot id: A0A1I7JM88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane

388950:A0W33 RS05770
gene id: 388950:A0W33_RS05770
uniprot id: A0A1I7K9X1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

388950:A0W33 RS04580
gene id: 388950:A0W33_RS04580
uniprot id: A0A1I7K2W8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 87 family.
messages: Membrane

388950:A0W33 RS03755
gene id: 388950:A0W33_RS03755
uniprot id: A0A1I7JY34
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

388950:A0W33 RS09150
gene id: 388950:A0W33_RS09150
uniprot id: A0A1I7HV82
names: Subcellular Location Annotation
messages: Membrane

388950:A0W33 RS13740
gene id: 388950:A0W33_RS13740
uniprot id: A0A1I7KLG0
names: Similarity
messages: Belongs to the catalase family.

388950:A0W33 RS06145
gene id: 388950:A0W33_RS06145
uniprot id: A0A1I7ILV6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

388950:A0W33 RS02625
gene id: 388950:A0W33_RS02625
uniprot id: A0A1I7H296
names: Similarity
messages: Belongs to the peptidase S49 family.

388950:A0W33 RS15400
gene id: 388950:A0W33_RS15400
uniprot id: A0A1I7KIH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

388950:A0W33 RS19445
gene id: 388950:A0W33_RS19445
uniprot id: A0A1I7G896
names: Similarity
messages: Belongs to the TrpC family.

388950:A0W33 RS01790
gene id: 388950:A0W33_RS01790
uniprot id: A0A1I7GU72
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the ferredoxin--NADP reductase type 2 family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

388950:A0W33 RS19400
gene id: 388950:A0W33_RS19400
uniprot id: A0A1I7G7G2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

388950:A0W33 RS16310
gene id: 388950:A0W33_RS16310
uniprot id: A0A1I7FFF8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

388950:A0W33 RS18025
gene id: 388950:A0W33_RS18025
uniprot id: A0A1I7FW56
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

388950:A0W33 RS19600
gene id: 388950:A0W33_RS19600
uniprot id: A0A1I7G8Q4
names: Function
messages: Might have a role analogous to that of eukaryotic histone proteins.

388950:A0W33 RS08470
gene id: 388950:A0W33_RS08470
uniprot id: A0A1I7I1E2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

388950:A0W33 RS20635
gene id: 388950:A0W33_RS20635
uniprot id: A0A1I7INJ1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

388950:A0W33 RS00770
gene id: 388950:A0W33_RS00770
uniprot id: A0A1I7GJ22
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

388950:A0W33 RS01930
gene id: 388950:A0W33_RS01930
uniprot id: A0A1I7GUV0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

388950:A0W33 RS12695
gene id: 388950:A0W33_RS12695
uniprot id: A0A1I7J4Z6
names: Subcellular Location Annotation
messages: Membrane

388950:A0W33 RS09230
gene id: 388950:A0W33_RS09230
uniprot id: A0A1I7HUC2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 3-HAO family.
messages: Binds 2 Fe(2+) ions per subunit.
messages: Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.

388950:A0W33 RS15145
gene id: 388950:A0W33_RS15145
uniprot id: A0A1I7KGW6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

388950:A0W33 RS10080
gene id: 388950:A0W33_RS10080
uniprot id: A0A1I7JMB0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

388950:A0W33 RS06400
gene id: 388950:A0W33_RS06400
uniprot id: A0A1I7IJD8
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.

388950:A0W33 RS02395
gene id: 388950:A0W33_RS02395
uniprot id: A0A1I7GZM9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
messages: Cytoplasm
messages: Homodimer. Forms a heterotetramer with IscU, interacts with other sulfur acceptors.
messages: Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.

388950:A0W33 RS18355
gene id: 388950:A0W33_RS18355
uniprot id: A0A1I7FYV1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

388950:A0W33 RS03840
gene id: 388950:A0W33_RS03840
uniprot id: A0A1I7JYK5
names: Similarity
messages: Belongs to the peptidase S8 family.

388950:A0W33 RS04390
gene id: 388950:A0W33_RS04390
uniprot id: A0A1I7K252
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.

388950:A0W33 RS10585
gene id: 388950:A0W33_RS10585
uniprot id: A0A1I7JIT3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

388950:A0W33 RS01860
gene id: 388950:A0W33_RS01860
uniprot id: A0A1I7GUA2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase Z family.
messages: Binds 2 Zn(2+) ions.
messages: Homodimer.
messages: Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.

388950:A0W33 RS10210
gene id: 388950:A0W33_RS10210
uniprot id: A0A1I7JLE9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

388950:A0W33 RS16200
gene id: 388950:A0W33_RS16200
uniprot id: A0A1I7FE36
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

388950:A0W33 RS15415
gene id: 388950:A0W33_RS15415
uniprot id: A0A1I7KIH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

388950:A0W33 RS17720
gene id: 388950:A0W33_RS17720
uniprot id: A0A1I7FST7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Cell membrane
messages: Membrane

388950:A0W33 RS17100
gene id: 388950:A0W33_RS17100
uniprot id: A0A1I7FMD1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

388950:A0W33 RS14185
gene id: 388950:A0W33_RS14185
uniprot id: A0A1I7KUQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Cell wall formation.
messages: Cytoplasm

388950:A0W33 RS00070
gene id: 388950:A0W33_RS00070
uniprot id: A0A1I7GCX7
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

388950:A0W33 RS09400
gene id: 388950:A0W33_RS09400
uniprot id: A0A1I7HSP9
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

388950:A0W33 RS15695
gene id: 388950:A0W33_RS15695
uniprot id: A0A1I7KWS1
names: Function
names: Similarity
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

388950:A0W33 RS13660
gene id: 388950:A0W33_RS13660
uniprot id: A0A1I7KLP7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

388950:A0W33 RS10595
gene id: 388950:A0W33_RS10595
uniprot id: A0A1I7JIQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

388950:A0W33 RS07375
gene id: 388950:A0W33_RS07375
uniprot id: A0A1I7IB31
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

388950:A0W33 RS06640
gene id: 388950:A0W33_RS06640
uniprot id: A0A1I7IH96
names: Similarity
messages: Belongs to the ACC deaminase/D-cysteine desulfhydrase family.

388950:A0W33 RS10670
gene id: 388950:A0W33_RS10670
uniprot id: A0A1I7JIG9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

388950:A0W33 RS17840
gene id: 388950:A0W33_RS17840
uniprot id: A0A1I7FU52
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

388950:A0W33 RS01865
gene id: 388950:A0W33_RS01865
uniprot id: A0A1I7GUE2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

388950:A0W33 RS12290
gene id: 388950:A0W33_RS12290
uniprot id: A0A1I7J873
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

388950:A0W33 RS00435
gene id: 388950:A0W33_RS00435
uniprot id: A0A1I7GGC1
names: Similarity
messages: Belongs to the SCO1/2 family.

388950:A0W33 RS01450
gene id: 388950:A0W33_RS01450
uniprot id: A0A1I7GQW9
names: Subcellular Location Annotation
messages: Membrane

388950:A0W33 RS17650
gene id: 388950:A0W33_RS17650
uniprot id: A0A1I7FS52
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-3 family.
messages: Cytoplasm
messages: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
messages: Monomer.

388950:A0W33 RS17300
gene id: 388950:A0W33_RS17300
uniprot id: A0A1I7FP10
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

388950:A0W33 RS13345
gene id: 388950:A0W33_RS13345
uniprot id: A0A1I7J036
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.

388950:A0W33 RS07600
gene id: 388950:A0W33_RS07600
uniprot id: A0A1I7I8Y2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acyl-ACP thioesterase family.
messages: chloroplast

388950:A0W33 RS19205
gene id: 388950:A0W33_RS19205
uniprot id: A0A1I7G6I8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

388950:A0W33 RS00775
gene id: 388950:A0W33_RS00775
uniprot id: A0A1I7GJ77
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

388950:A0W33 RS16485
gene id: 388950:A0W33_RS16485
uniprot id: A0A1I7FH48
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

388950:A0W33 RS03870
gene id: 388950:A0W33_RS03870
uniprot id: A0A1I7JYK7
names: Subcellular Location Annotation
messages: Endoplasmic reticulum
messages: Golgi apparatus
messages: Lysosome
messages: Secreted

388950:A0W33 RS15940
gene id: 388950:A0W33_RS15940
uniprot id: A0A1I7KT17
names: Similarity
messages: Belongs to the peptidase S13 family.

388950:A0W33 RS06660
gene id: 388950:A0W33_RS06660
uniprot id: A0A1I7IGY8
names: Similarity
messages: Belongs to the CarB family.

388950:A0W33 RS02170
gene id: 388950:A0W33_RS02170
uniprot id: A0A1I7GXI4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

388950:A0W33 RS05430
gene id: 388950:A0W33_RS05430
uniprot id: A0A1I7K8E5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

388950:A0W33 RS03300
gene id: 388950:A0W33_RS03300
uniprot id: A0A1I7H6Y2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

388950:A0W33 RS00010
gene id: 388950:A0W33_RS00010
uniprot id: A0A1I7GCK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

388950:A0W33 RS00050
gene id: 388950:A0W33_RS00050
uniprot id: A0A1I7GCI4
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.

388950:A0W33 RS19470
gene id: 388950:A0W33_RS19470
uniprot id: A0A1I7G7V0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: In the N-terminal section; belongs to the histidinol-phosphatase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

388950:A0W33 RS10185
gene id: 388950:A0W33_RS10185
uniprot id: A0A1I7JLR0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

388950:A0W33 RS11450
gene id: 388950:A0W33_RS11450
uniprot id: A0A1I7JDG4
names: Similarity
messages: Belongs to the SIS family. GutQ/KpsF subfamily.

388950:A0W33 RS16590
gene id: 388950:A0W33_RS16590
uniprot id: A0A1I7FI27
names: Function
names: Similarity
messages: Belongs to the APS kinase family.
messages: Catalyzes the synthesis of activated sulfate.

388950:A0W33 RS18460
gene id: 388950:A0W33_RS18460
uniprot id: A0A1I7FZF5
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

388950:A0W33 RS17145
gene id: 388950:A0W33_RS17145
uniprot id: A0A1I7FMN5
names: Subcellular Location Annotation
messages: Membrane

388950:A0W33 RS03015
gene id: 388950:A0W33_RS03015
uniprot id: A0A1I7H4Z9
names: Similarity
messages: Belongs to the polysaccharide synthase family.

388950:A0W33 RS14100
gene id: 388950:A0W33_RS14100
uniprot id: A0A1I7KV00
names: Similarity
messages: Belongs to the peptidase S51 family.

388950:A0W33 RS08510
gene id: 388950:A0W33_RS08510
uniprot id: A0A1I7I0U5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm
messages: Homodimer.

388950:A0W33 RS14465
gene id: 388950:A0W33_RS14465
uniprot id: A0A1I7KX26
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
messages: Cell membrane
messages: Membrane
messages: Transport of potassium into the cell.

388950:A0W33 RS03960
gene id: 388950:A0W33_RS03960
uniprot id: A0A1I7JZ77
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

388950:A0W33 RS17435
gene id: 388950:A0W33_RS17435
uniprot id: A0A1I7FQ78
names: Similarity
messages: Belongs to the peptidase S24 family.

388950:A0W33 RS04040
gene id: 388950:A0W33_RS04040
uniprot id: A0A1I7JZQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

388950:A0W33 RS19755
gene id: 388950:A0W33_RS19755
uniprot id: A0A1I7GAJ1
names: Similarity
messages: Belongs to the ParB family.

388950:A0W33 RS06950
gene id: 388950:A0W33_RS06950
uniprot id: A0A1I7IE58
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

388950:A0W33 RS11685
gene id: 388950:A0W33_RS11685
uniprot id: A0A1I7JC48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Membrane

388950:A0W33 RS04690
gene id: 388950:A0W33_RS04690
uniprot id: A0A1I7K3S7
names: Similarity
messages: Belongs to the CvfB family.

388950:A0W33 RS02175
gene id: 388950:A0W33_RS02175
uniprot id: A0A1I7GXJ7
names: Subcellular Location Annotation
messages: Membrane

388950:A0W33 RS07760
gene id: 388950:A0W33_RS07760
uniprot id: A0A1I7I7B0
names: Similarity
messages: Belongs to the peptidase U62 family.

388950:A0W33 RS04170
gene id: 388950:A0W33_RS04170
uniprot id: A0A1I7K0I5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

388950:A0W33 RS13595
gene id: 388950:A0W33_RS13595
uniprot id: A0A1I7KLZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

388950:A0W33 RS11040
gene id: 388950:A0W33_RS11040
uniprot id: A0A1I7JG19
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

388950:A0W33 RS18125
gene id: 388950:A0W33_RS18125
uniprot id: A0A1I7FX31
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

388950:A0W33 RS10790
gene id: 388950:A0W33_RS10790
uniprot id: A0A1I7JHK3
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

388950:A0W33 RS05250
gene id: 388950:A0W33_RS05250
uniprot id: A0A1I7K7E4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

388950:A0W33 RS17930
gene id: 388950:A0W33_RS17930
uniprot id: A0A1I7FV48
names: Similarity
messages: Belongs to the LacAB/RpiB family.

388950:A0W33 RS15585
gene id: 388950:A0W33_RS15585
uniprot id: A0A1I7KWE6
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

388950:A0W33 RS05395
gene id: 388950:A0W33_RS05395
uniprot id: A0A1I7K8E0
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

388950:A0W33 RS06845
gene id: 388950:A0W33_RS06845
uniprot id: A0A1I7IF58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

388950:A0W33 RS19355
gene id: 388950:A0W33_RS19355
uniprot id: A0A1I7G726
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

388950:A0W33 RS17785
gene id: 388950:A0W33_RS17785
uniprot id: A0A1I7FTJ5
names: Similarity
messages: Belongs to the peptidase C40 family.

388950:A0W33 RS03205
gene id: 388950:A0W33_RS03205
uniprot id: A0A1I7H698
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxC family.
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

388950:A0W33 RS07240
gene id: 388950:A0W33_RS07240
uniprot id: A0A1I7IC44
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

388950:A0W33 RS13900
gene id: 388950:A0W33_RS13900
uniprot id: A0A1I7KKV3
names: Similarity
messages: Belongs to the SAM hydrolase / SAM-dependent halogenase family.

388950:A0W33 RS08650
gene id: 388950:A0W33_RS08650
uniprot id: A0A1I7HZF7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metallo-beta-lactamase superfamily. Class-B beta-lactamase family.
messages: Confers resistance to the different beta-lactams antibiotics (penicillin, cephalosporin and carbapenem) via the hydrolysis of the beta-lactam ring.
messages: Monomer.
messages: Periplasm

388950:A0W33 RS02280
gene id: 388950:A0W33_RS02280
uniprot id: A0A1I7GZ23
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

388950:A0W33 RS08970
gene id: 388950:A0W33_RS08970
uniprot id: A0A1I7HWP6
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

388950:A0W33 RS18080
gene id: 388950:A0W33_RS18080
uniprot id: A0A1I7FX34
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

388950:A0W33 RS17995
gene id: 388950:A0W33_RS17995
uniprot id: A0A1I7FVS1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

388950:A0W33 RS01540
gene id: 388950:A0W33_RS01540
uniprot id: A0A1I7GRI5
names: Similarity
messages: Belongs to the universal stress protein A family.

388950:A0W33 RS10725
gene id: 388950:A0W33_RS10725
uniprot id: A0A1I7JI66
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

388950:A0W33 RS05105
gene id: 388950:A0W33_RS05105
uniprot id: A0A1I7K699
names: Similarity
messages: Belongs to the PspA/IM30 family.

388950:A0W33 RS12760
gene id: 388950:A0W33_RS12760
uniprot id: A0A1I7J4J9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

388950:A0W33 RS06270
gene id: 388950:A0W33_RS06270
uniprot id: A0A1I7IKV3
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

388950:A0W33 RS10770
gene id: 388950:A0W33_RS10770
uniprot id: A0A1I7JHW3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

388950:A0W33 RS17805
gene id: 388950:A0W33_RS17805
uniprot id: A0A1I7FTJ7
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

388950:A0W33 RS17035
gene id: 388950:A0W33_RS17035
uniprot id: A0A1I7FLU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
messages: Membrane

388950:A0W33 RS17605
gene id: 388950:A0W33_RS17605
uniprot id: A0A1I7FRU7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.

388950:A0W33 RS08745
gene id: 388950:A0W33_RS08745
uniprot id: A0A1I7HYR7
names: Similarity
messages: Belongs to the RecJ family.

388950:A0W33 RS11495
gene id: 388950:A0W33_RS11495
uniprot id: A0A1I7JD47
names: Similarity
messages: Belongs to the SusD family.

388950:A0W33 RS18910
gene id: 388950:A0W33_RS18910
uniprot id: A0A1I7G3E3
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

388950:A0W33 RS18935
gene id: 388950:A0W33_RS18935
uniprot id: A0A1I7G496
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

388950:A0W33 RS20575
gene id: 388950:A0W33_RS20575
uniprot id: A0A1I7KQ33
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Homodimer.

388950:A0W33 RS14755
gene id: 388950:A0W33_RS14755
uniprot id: A0A1I7KF51
names: Similarity
messages: Belongs to the glycosyl hydrolase 57 family.

388950:A0W33 RS12165
gene id: 388950:A0W33_RS12165
uniprot id: A0A1I7J917
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

388950:A0W33 RS04435
gene id: 388950:A0W33_RS04435
uniprot id: A0A1I7K212
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

388950:A0W33 RS07390
gene id: 388950:A0W33_RS07390
uniprot id: A0A1I7IAQ7
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

388950:A0W33 RS08795
gene id: 388950:A0W33_RS08795
uniprot id: A0A1I7HY47
names: Similarity
messages: Belongs to the RutC family.

388950:A0W33 RS03515
gene id: 388950:A0W33_RS03515
uniprot id: A0A1I7JX07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

388950:A0W33 RS10935
gene id: 388950:A0W33_RS10935
uniprot id: A0A1I7JGM2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

388950:A0W33 RS12130
gene id: 388950:A0W33_RS12130
uniprot id: A0A1I7J970
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

388950:A0W33 RS13515
gene id: 388950:A0W33_RS13515
uniprot id: A0A1I7KMC4
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

388950:A0W33 RS19245
gene id: 388950:A0W33_RS19245
uniprot id: A0A1I7G6I7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane

388950:A0W33 RS10805
gene id: 388950:A0W33_RS10805
uniprot id: A0A1I7JHL8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

388950:A0W33 RS12710
gene id: 388950:A0W33_RS12710
uniprot id: A0A1I7J4X3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

388950:A0W33 RS09905
gene id: 388950:A0W33_RS09905
uniprot id: A0A1I7JNJ7
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

388950:A0W33 RS17590
gene id: 388950:A0W33_RS17590
uniprot id: A0A1I7FS18
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

388950:A0W33 RS09780
gene id: 388950:A0W33_RS09780
uniprot id: A0A1I7JP65
names: Subcellular Location Annotation
messages: Membrane

388950:A0W33 RS11590
gene id: 388950:A0W33_RS11590
uniprot id: A0A1I7JCM0
names: Cofactor
names: Similarity
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.
messages: Binds 1 Fe cation per subunit.
messages: Binds 1 zinc ion per subunit.

388950:A0W33 RS00115
gene id: 388950:A0W33_RS00115
uniprot id: A0A1I7GDC9
names: Similarity
messages: Belongs to the creatininase superfamily.

388950:A0W33 RS14765
gene id: 388950:A0W33_RS14765
uniprot id: A0A1I7KEU8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgE subfamily.
messages: Homodimer.
messages: Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1->4)-glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB.

388950:A0W33 RS05215
gene id: 388950:A0W33_RS05215
uniprot id: A0A1I7K7B1
names: Subcellular Location Annotation
messages: Membrane

388950:A0W33 RS06465
gene id: 388950:A0W33_RS06465
uniprot id: A0A1I7IIU0
names: Similarity
messages: Belongs to the Skp family.

388950:A0W33 RS13300
gene id: 388950:A0W33_RS13300
uniprot id: A0A1I7J0G4
names: Subcellular Location Annotation
messages: Membrane

388950:A0W33 RS04445
gene id: 388950:A0W33_RS04445
uniprot id: A0A1I7K277
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

388950:A0W33 RS19845
gene id: 388950:A0W33_RS19845
uniprot id: A0A1I7GAQ2
names: Similarity
messages: Belongs to the peptidase C40 family.

388950:A0W33 RS06425
gene id: 388950:A0W33_RS06425
uniprot id: A0A1I7IJA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

388950:A0W33 RS00030
gene id: 388950:A0W33_RS00030
uniprot id: A0A1I7GCS8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

388950:A0W33 RS19050
gene id: 388950:A0W33_RS19050
uniprot id: A0A1I7G4V8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

388950:A0W33 RS05940
gene id: 388950:A0W33_RS05940
uniprot id: A0A1I7INN5
names: Similarity
messages: Belongs to the peptidase S41A family.

388950:A0W33 RS14840
gene id: 388950:A0W33_RS14840
uniprot id: A0A1I7KFK7
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

388950:A0W33 RS13280
gene id: 388950:A0W33_RS13280
uniprot id: A0A1I7J0M6
names: Subcellular Location Annotation
messages: Membrane

388950:A0W33 RS01705
gene id: 388950:A0W33_RS01705
uniprot id: A0A1I7GTM0
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

388950:A0W33 RS11515
gene id: 388950:A0W33_RS11515
uniprot id: A0A1I7JD09
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

388950:A0W33 RS07460
gene id: 388950:A0W33_RS07460
uniprot id: A0A1I7IA06
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

388950:A0W33 RS20545
gene id: 388950:A0W33_RS20545
uniprot id: A0A1I7KPY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0394 family.
messages: Membrane

388950:A0W33 RS06345
gene id: 388950:A0W33_RS06345
uniprot id: A0A1I7IK16
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A lyase-type mechanism (elimination/hydration) is suggested for the cleavage of the lactyl ether bond of MurNAc 6-phosphate, with the formation of an alpha,beta-unsaturated aldehyde intermediate with (E)-stereochemistry, followed by the syn addition of water to give product.
messages: Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
messages: Homodimer.
messages: Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate.

388950:A0W33 RS09085
gene id: 388950:A0W33_RS09085
uniprot id: A0A1I7HVQ4
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain.

388950:A0W33 RS02075
gene id: 388950:A0W33_RS02075
uniprot id: A0A1I7GWD9
names: Subcellular Location Annotation
messages: Mitochondrion

388950:A0W33 RS10695
gene id: 388950:A0W33_RS10695
uniprot id: A0A1I7JI92
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

388950:A0W33 RS14405
gene id: 388950:A0W33_RS14405
uniprot id: A0A1I7KXH8
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

388950:A0W33 RS11930
gene id: 388950:A0W33_RS11930
uniprot id: A0A1I7JAP5
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

388950:A0W33 RS01855
gene id: 388950:A0W33_RS01855
uniprot id: A0A1I7GUA3
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

388950:A0W33 RS06590
gene id: 388950:A0W33_RS06590
uniprot id: A0A1I7IHT8
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

388950:A0W33 RS10600
gene id: 388950:A0W33_RS10600
uniprot id: A0A1I7JIM9
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

388950:A0W33 RS11970
gene id: 388950:A0W33_RS11970
uniprot id: A0A1I7JA91
names: Subcellular Location Annotation
messages: Membrane

388950:A0W33 RS11950
gene id: 388950:A0W33_RS11950
uniprot id: A0A1I7JAN9
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

388950:A0W33 RS17565
gene id: 388950:A0W33_RS17565
uniprot id: A0A1I7FR73
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

388950:A0W33 RS13350
gene id: 388950:A0W33_RS13350
uniprot id: A0A1I7J080
names: Function
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

388950:A0W33 RS10650
gene id: 388950:A0W33_RS10650
uniprot id: A0A1I7JIG7
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

388950:A0W33 RS09165
gene id: 388950:A0W33_RS09165
uniprot id: A0A1I7HV32
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the flotillin-like FloA family.
messages: Cell membrane
messages: Found in functional membrane microdomains (FMM) that may be equivalent to eukaryotic membrane rafts FMMs are highly dynamic and increase in number as cells age. Flotillins are thought to be important factors in membrane fluidity.
messages: Homooligomerizes.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane raft

388950:A0W33 RS04005
gene id: 388950:A0W33_RS04005
uniprot id: A0A1I7JZF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

388950:A0W33 RS00525
gene id: 388950:A0W33_RS00525
uniprot id: A0A1I7GGX7
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

388950:A0W33 RS18350
gene id: 388950:A0W33_RS18350
uniprot id: A0A1I7FZ35
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. SOTCase family.
messages: Catalyzes the transfer of the carbamoyl group from carbamoyl phosphate to the delta-amino group of N(2)-succinyl-L-ornithine to produce N(2)-succinyl-L-citrulline. Is essential for arginine biosynthesis.
messages: Homotrimer.

388950:A0W33 RS18435
gene id: 388950:A0W33_RS18435
uniprot id: A0A1I7FZT1
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

388950:A0W33 RS13155
gene id: 388950:A0W33_RS13155
uniprot id: A0A1I7J1H5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

388950:A0W33 RS12250
gene id: 388950:A0W33_RS12250
uniprot id: A0A1I7J8F1
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

388950:A0W33 RS11735
gene id: 388950:A0W33_RS11735
uniprot id: A0A1I7JBM5
names: Similarity
messages: Belongs to the thioredoxin family.

388950:A0W33 RS03460
gene id: 388950:A0W33_RS03460
uniprot id: A0A1I7JWN4
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

388950:A0W33 RS00980
gene id: 388950:A0W33_RS00980
uniprot id: A0A1I7GKX4
names: Similarity
messages: Belongs to the pirin family.

388950:A0W33 RS01825
gene id: 388950:A0W33_RS01825
uniprot id: A0A1I7GTX1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

388950:A0W33 RS10775
gene id: 388950:A0W33_RS10775
uniprot id: A0A1I7JHR1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

388950:A0W33 RS18495
gene id: 388950:A0W33_RS18495
uniprot id: A0A1I7FZS5
names: Subcellular Location Annotation
messages: Membrane

388950:A0W33 RS06965
gene id: 388950:A0W33_RS06965
uniprot id: A0A1I7IDZ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

388950:A0W33 RS17260
gene id: 388950:A0W33_RS17260
uniprot id: A0A1I7FNP8
names: Subcellular Location Annotation
messages: Membrane

388950:A0W33 RS07365
gene id: 388950:A0W33_RS07365
uniprot id: A0A1I7IB22
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
messages: Cytoplasm

388950:A0W33 RS06240
gene id: 388950:A0W33_RS06240
uniprot id: A0A1I7IL28
names: Cofactor
names: Function
names: Similarity
messages: Adenine glycosylase active on G-A mispairs.
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.

388950:A0W33 RS10860
gene id: 388950:A0W33_RS10860
uniprot id: A0A1I7JH68
names: Similarity
messages: Belongs to the heat shock protein 70 family.

388950:A0W33 RS09040
gene id: 388950:A0W33_RS09040
uniprot id: A0A1I7HW47
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

388950:A0W33 RS10630
gene id: 388950:A0W33_RS10630
uniprot id: A0A1I7JIN6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

388950:A0W33 RS16740
gene id: 388950:A0W33_RS16740
uniprot id: A0A1I7FJC4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

388950:A0W33 RS04530
gene id: 388950:A0W33_RS04530
uniprot id: A0A1I7K2J9
names: Subcellular Location Annotation
messages: Membrane

388950:A0W33 RS19890
gene id: 388950:A0W33_RS19890
uniprot id: A0A1I7GB17
names: Similarity
messages: Belongs to the ribF family.

388950:A0W33 RS04265
gene id: 388950:A0W33_RS04265
uniprot id: A0A1I7K0Z0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

388950:A0W33 RS13380
gene id: 388950:A0W33_RS13380
uniprot id: A0A1I7IZZ6
names: Similarity
messages: Belongs to the Fur family.

388950:A0W33 RS04375
gene id: 388950:A0W33_RS04375
uniprot id: A0A1I7K1S5
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

388950:A0W33 RS19745
gene id: 388950:A0W33_RS19745
uniprot id: A0A1I7G9Y7
names: Similarity
messages: Belongs to the UPF0173 family.

388950:A0W33 RS06250
gene id: 388950:A0W33_RS06250
uniprot id: A0A1I7IL17
names: Subcellular Location Annotation
messages: Membrane

388950:A0W33 RS14255
gene id: 388950:A0W33_RS14255
uniprot id: A0A1I7KV11
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

388950:A0W33 RS09975
gene id: 388950:A0W33_RS09975
uniprot id: A0A1I7JN08
names: Similarity
messages: Belongs to the MreC family.

388950:A0W33 RS09450
gene id: 388950:A0W33_RS09450
uniprot id: A0A1I7HSX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

388950:A0W33 RS08455
gene id: 388950:A0W33_RS08455
uniprot id: A0A1I7I1H0
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

388950:A0W33 RS04155
gene id: 388950:A0W33_RS04155
uniprot id: A0A1I7K065
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

388950:A0W33 RS16250
gene id: 388950:A0W33_RS16250
uniprot id: A0A1I7FEW0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

388950:A0W33 RS05535
gene id: 388950:A0W33_RS05535
uniprot id: A0A1I7K8V4
names: Subcellular Location Annotation
messages: Membrane

388950:A0W33 RS16810
gene id: 388950:A0W33_RS16810
uniprot id: A0A1I7FKB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

388950:A0W33 RS21045
gene id: 388950:A0W33_RS21045
uniprot id: A0A1I7H414
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

388950:A0W33 RS15785
gene id: 388950:A0W33_RS15785
uniprot id: A0A1I7KTN8
names: Cofactor
names: Similarity
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.

388950:A0W33 RS14680
gene id: 388950:A0W33_RS14680
uniprot id: A0A1I7KED4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

388950:A0W33 RS10840
gene id: 388950:A0W33_RS10840
uniprot id: A0A1I7JHC3
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

388950:A0W33 RS16155
gene id: 388950:A0W33_RS16155
uniprot id: A0A1I7KS62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

388950:A0W33 RS07175
gene id: 388950:A0W33_RS07175
uniprot id: A0A1I7ICP9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

388950:A0W33 RS19515
gene id: 388950:A0W33_RS19515
uniprot id: A0A1I7G842
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

388950:A0W33 RS12430
gene id: 388950:A0W33_RS12430
uniprot id: A0A1I7J740
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

388950:A0W33 RS14805
gene id: 388950:A0W33_RS14805
uniprot id: A0A1I7KFH9
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

388950:A0W33 RS19385
gene id: 388950:A0W33_RS19385
uniprot id: A0A1I7G796
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

388950:A0W33 RS18655
gene id: 388950:A0W33_RS18655
uniprot id: A0A1I7G168
names: Similarity
messages: In the N-terminal section; belongs to the phytochrome family.

388950:A0W33 RS17985
gene id: 388950:A0W33_RS17985
uniprot id: A0A1I7FVR6
names: Subcellular Location Annotation
messages: Membrane

388950:A0W33 RS16525
gene id: 388950:A0W33_RS16525
uniprot id: A0A1I7FHA9
names: Similarity
messages: In the N-terminal section; belongs to the phytochrome family.

388950:A0W33 RS02630
gene id: 388950:A0W33_RS02630
uniprot id: A0A1I7H1T5
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

388950:A0W33 RS13695
gene id: 388950:A0W33_RS13695
uniprot id: A0A1I7KLK3
names: Subcellular Location Annotation
messages: Membrane

388950:A0W33 RS09845
gene id: 388950:A0W33_RS09845
uniprot id: A0A1I7JNV2
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

388950:A0W33 RS05990
gene id: 388950:A0W33_RS05990
uniprot id: A0A1I7INA9
names: Similarity
messages: Belongs to the DEAD box helicase family.

388950:A0W33 RS13810
gene id: 388950:A0W33_RS13810
uniprot id: A0A1I7KLA1
names: Subcellular Location Annotation
messages: Membrane

388950:A0W33 RS18765
gene id: 388950:A0W33_RS18765
uniprot id: A0A1I7G2I0
names: Function
names: Similarity
messages: Belongs to the peptidase S51 family.
messages: Exopeptidase that catalyzes the hydrolytic cleavage of multi-L-arginyl-poly-L-aspartic acid (cyanophycin; a water-insoluble reserve polymer) into aspartate-arginine dipeptides.

388950:A0W33 RS01055
gene id: 388950:A0W33_RS01055
uniprot id: A0A1I7GLR4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

388950:A0W33 RS18220
gene id: 388950:A0W33_RS18220
uniprot id: A0A1I7FXT3
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

388950:A0W33 RS10155
gene id: 388950:A0W33_RS10155
uniprot id: A0A1I7JLU1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.

388950:A0W33 RS03815
gene id: 388950:A0W33_RS03815
uniprot id: A0A1I7JYJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

388950:A0W33 RS02975
gene id: 388950:A0W33_RS02975
uniprot id: A0A1I7H4I6
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

388950:A0W33 RS09605
gene id: 388950:A0W33_RS09605
uniprot id: A0A1I7HQY9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

388950:A0W33 RS12325
gene id: 388950:A0W33_RS12325
uniprot id: A0A1I7J7T5
names: Similarity
messages: Belongs to the ComB family.

388950:A0W33 RS02185
gene id: 388950:A0W33_RS02185
uniprot id: A0A1I7GXK8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

388950:A0W33 RS11820
gene id: 388950:A0W33_RS11820
uniprot id: A0A1I7JB94
names: Similarity
messages: Belongs to the peptidase M24B family.

388950:A0W33 RS10735
gene id: 388950:A0W33_RS10735
uniprot id: A0A1I7JI04
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

388950:A0W33 RS11165
gene id: 388950:A0W33_RS11165
uniprot id: A0A1I7JF51
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

388950:A0W33 RS08180
gene id: 388950:A0W33_RS08180
uniprot id: A0A1I7I3T6
names: Subcellular Location Annotation
messages: Membrane

388950:A0W33 RS19225
gene id: 388950:A0W33_RS19225
uniprot id: A0A1I7G654
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

388950:A0W33 RS13290
gene id: 388950:A0W33_RS13290
uniprot id: A0A1I7J0I7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

388950:A0W33 RS16225
gene id: 388950:A0W33_RS16225
uniprot id: A0A1I7FEF6
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

388950:A0W33 RS16220
gene id: 388950:A0W33_RS16220
uniprot id: A0A1I7FE76
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

388950:A0W33 RS06405
gene id: 388950:A0W33_RS06405
uniprot id: A0A1I7IJB7
names: Similarity
messages: Belongs to the phosphohexose mutase family.

388950:A0W33 RS15100
gene id: 388950:A0W33_RS15100
uniprot id: A0A1I7KGN0
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

388950:A0W33 RS10390
gene id: 388950:A0W33_RS10390
uniprot id: A0A1I7JKB2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

388950:A0W33 RS15965
gene id: 388950:A0W33_RS15965
uniprot id: A0A1I7KSX5
names: Subcellular Location Annotation
messages: Membrane

388950:A0W33 RS04515
gene id: 388950:A0W33_RS04515
uniprot id: A0A1I7K2K9
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

388950:A0W33 RS10075
gene id: 388950:A0W33_RS10075
uniprot id: A0A1I7JMB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmB/CycW/HelB family.
messages: Membrane

388950:A0W33 RS17660
gene id: 388950:A0W33_RS17660
uniprot id: A0A1I7FSE6
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

388950:A0W33 RS07470
gene id: 388950:A0W33_RS07470
uniprot id: A0A1I7I9Y4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

388950:A0W33 RS11485
gene id: 388950:A0W33_RS11485
uniprot id: A0A1I7JD67
names: Similarity
messages: Belongs to the glycosyl hydrolase 51 family.

388950:A0W33 RS03995
gene id: 388950:A0W33_RS03995
uniprot id: A0A1I7JZ92
names: Function
names: Similarity
messages: Belongs to the mannonate dehydratase family.
messages: Catalyzes the dehydration of D-mannonate.

388950:A0W33 RS00630
gene id: 388950:A0W33_RS00630
uniprot id: A0A1I7GI26
names: Subcellular Location Annotation
messages: Membrane

388950:A0W33 RS10025
gene id: 388950:A0W33_RS10025
uniprot id: A0A1I7JMR6
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Homotetramer.

388950:A0W33 RS10930
gene id: 388950:A0W33_RS10930
uniprot id: A0A1I7JGP5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

388950:A0W33 RS18160
gene id: 388950:A0W33_RS18160
uniprot id: A0A1I7FXH1
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

388950:A0W33 RS19180
gene id: 388950:A0W33_RS19180
uniprot id: A0A1I7G5R8
names: Function
names: Similarity
messages: Belongs to the LpxK family.
messages: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

388950:A0W33 RS03200
gene id: 388950:A0W33_RS03200
uniprot id: A0A1I7H687
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

388950:A0W33 RS14860
gene id: 388950:A0W33_RS14860
uniprot id: A0A1I7KFP4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

388950:A0W33 RS11020
gene id: 388950:A0W33_RS11020
uniprot id: A0A1I7JG55
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

388950:A0W33 RS12265
gene id: 388950:A0W33_RS12265
uniprot id: A0A1I7J8H9
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

388950:A0W33 RS02330
gene id: 388950:A0W33_RS02330
uniprot id: A0A1I7GZ38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

388950:A0W33 RS10330
gene id: 388950:A0W33_RS10330
uniprot id: A0A1I7JKL6
names: Subcellular Location Annotation
messages: Membrane

388950:A0W33 RS09110
gene id: 388950:A0W33_RS09110
uniprot id: A0A1I7HVF0
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

388950:A0W33 RS16645
gene id: 388950:A0W33_RS16645
uniprot id: A0A1I7FIH4
names: Subcellular Location Annotation
messages: Membrane

388950:A0W33 RS09175
gene id: 388950:A0W33_RS09175
uniprot id: A0A1I7HUU6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.
messages: Cytoplasm
messages: Homodimer.

388950:A0W33 RS14500
gene id: 388950:A0W33_RS14500
uniprot id: A0A1I7KYC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

388950:A0W33 RS13275
gene id: 388950:A0W33_RS13275
uniprot id: A0A1I7J0Q5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane

388950:A0W33 RS04785
gene id: 388950:A0W33_RS04785
uniprot id: A0A1I7K4K0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

388950:A0W33 RS00340
gene id: 388950:A0W33_RS00340
uniprot id: A0A1I7GFB9
names: Subcellular Location Annotation
messages: Cytoplasm

388950:A0W33 RS08845
gene id: 388950:A0W33_RS08845
uniprot id: A0A1I7HXS9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

388950:A0W33 RS17935
gene id: 388950:A0W33_RS17935
uniprot id: A0A1I7FV12
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 2 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

388950:A0W33 RS09370
gene id: 388950:A0W33_RS09370
uniprot id: A0A1I7HSW2
names: Subcellular Location Annotation
messages: Membrane

388950:A0W33 RS12655
gene id: 388950:A0W33_RS12655
uniprot id: A0A1I7J5D2
names: Similarity
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.

388950:A0W33 RS03225
gene id: 388950:A0W33_RS03225
uniprot id: A0A1I7H686
names: Subcellular Location Annotation
messages: Membrane

388950:A0W33 RS09795
gene id: 388950:A0W33_RS09795
uniprot id: A0A1I7JP58
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

388950:A0W33 RS19645
gene id: 388950:A0W33_RS19645
uniprot id: A0A1I7G910
names: Subcellular Location Annotation
messages: Membrane

388950:A0W33 RS09980
gene id: 388950:A0W33_RS09980
uniprot id: A0A1I7JN02
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

388950:A0W33 RS03090
gene id: 388950:A0W33_RS03090
uniprot id: A0A1I7H5Y9
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

388950:A0W33 RS18145
gene id: 388950:A0W33_RS18145
uniprot id: A0A1I7FXA3
names: Similarity
messages: Belongs to the alkylbase DNA glycosidase AlkA family.

388950:A0W33 RS14235
gene id: 388950:A0W33_RS14235
uniprot id: A0A1I7KUQ1
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

388950:A0W33 RS06235
gene id: 388950:A0W33_RS06235
uniprot id: A0A1I7IL42
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

388950:A0W33 RS11170
gene id: 388950:A0W33_RS11170
uniprot id: A0A1I7JF64
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

388950:A0W33 RS09525
gene id: 388950:A0W33_RS09525
uniprot id: A0A1I7HRH6
names: Similarity
messages: Belongs to the acylphosphatase family.

388950:A0W33 RS17950
gene id: 388950:A0W33_RS17950
uniprot id: A0A1I7FVG1
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

388950:A0W33 RS10745
gene id: 388950:A0W33_RS10745
uniprot id: A0A1I7JHY7
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

388950:A0W33 RS17500
gene id: 388950:A0W33_RS17500
uniprot id: A0A1I7FQL5
names: Similarity
messages: Belongs to the arginase family.

388950:A0W33 RS05195
gene id: 388950:A0W33_RS05195
uniprot id: A0A1I7K707
names: Cofactor
names: Similarity
messages: Belongs to the peptidase S45 family.
messages: Binds 1 Ca(2+) ion per dimer.

388950:A0W33 RS09075
gene id: 388950:A0W33_RS09075
uniprot id: A0A1I7HVS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

388950:A0W33 RS12675
gene id: 388950:A0W33_RS12675
uniprot id: A0A1I7J556
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

388950:A0W33 RS17195
gene id: 388950:A0W33_RS17195
uniprot id: A0A1I7FN73
names: Similarity
messages: Belongs to the polysaccharide synthase family.

388950:A0W33 RS12440
gene id: 388950:A0W33_RS12440
uniprot id: A0A1I7J6S5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

388950:A0W33 RS02930
gene id: 388950:A0W33_RS02930
uniprot id: A0A1I7H467
names: Subcellular Location Annotation
messages: Membrane

388950:A0W33 RS19560
gene id: 388950:A0W33_RS19560
uniprot id: A0A1I7G8R1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

388950:A0W33 RS02890
gene id: 388950:A0W33_RS02890
uniprot id: A0A1I7H3T8
names: Similarity
messages: Belongs to the SusD family.

388950:A0W33 RS12490
gene id: 388950:A0W33_RS12490
uniprot id: A0A1I7J6E9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

388950:A0W33 RS12365
gene id: 388950:A0W33_RS12365
uniprot id: A0A1I7J7N7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

388950:A0W33 RS00685
gene id: 388950:A0W33_RS00685
uniprot id: A0A1I7GII8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

388950:A0W33 RS12725
gene id: 388950:A0W33_RS12725
uniprot id: A0A1I7J4S1
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.

388950:A0W33 RS09105
gene id: 388950:A0W33_RS09105
uniprot id: A0A1I7HVG9
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

388950:A0W33 RS12860
gene id: 388950:A0W33_RS12860
uniprot id: A0A1I7J3M0
names: Similarity
messages: Belongs to the SusD family.

388950:A0W33 RS07900
gene id: 388950:A0W33_RS07900
uniprot id: A0A1I7I682
names: Similarity
messages: Belongs to the ice-binding protein family.

388950:A0W33 RS17815
gene id: 388950:A0W33_RS17815
uniprot id: A0A1I7FTV8
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

388950:A0W33 RS08555
gene id: 388950:A0W33_RS08555
uniprot id: A0A1I7I0E4
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

388950:A0W33 RS15290
gene id: 388950:A0W33_RS15290
uniprot id: A0A1I7KHN3
names: Subcellular Location Annotation
messages: Membrane

388950:A0W33 RS03305
gene id: 388950:A0W33_RS03305
uniprot id: A0A1I7H711
names: Subcellular Location Annotation
messages: Membrane

388950:A0W33 RS09125
gene id: 388950:A0W33_RS09125
uniprot id: A0A1I7HVC2
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

388950:A0W33 RS14470
gene id: 388950:A0W33_RS14470
uniprot id: A0A1I7KX58
names: Subcellular Location Annotation
messages: Membrane

388950:A0W33 RS15600
gene id: 388950:A0W33_RS15600
uniprot id: A0A1I7KVX8
names: Similarity
messages: Belongs to the peptidase M24B family.

388950:A0W33 RS18455
gene id: 388950:A0W33_RS18455
uniprot id: A0A1I7FZH3
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

388950:A0W33 RS04980
gene id: 388950:A0W33_RS04980
uniprot id: A0A1I7K5H3
names: Similarity
messages: Belongs to the SusD family.

388950:A0W33 RS00095
gene id: 388950:A0W33_RS00095
uniprot id: A0A1I7GCY5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

388950:A0W33 RS18520
gene id: 388950:A0W33_RS18520
uniprot id: A0A1I7G005
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 2 residues (Tyr-54 and Arg-57) present in a large hydrophobic pocket are probably involved in substrate specificity. They are important for desuccinylation activity, but dispensable for deacetylation activity.
messages: Belongs to the sirtuin family. Class III subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form.

388950:A0W33 RS13330
gene id: 388950:A0W33_RS13330
uniprot id: A0A1I7J067
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily.
messages: Binds 1 NADP(+) per subunit.
messages: Catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose.
messages: Contains a large N-terminal NADP-binding domain, and a smaller C-terminal substrate-binding domain.
messages: Homopentamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

388950:A0W33 RS10810
gene id: 388950:A0W33_RS10810
uniprot id: A0A1I7JHH6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

388950:A0W33 RS02920
gene id: 388950:A0W33_RS02920
uniprot id: A0A1I7H452
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

388950:A0W33 RS08525
gene id: 388950:A0W33_RS08525
uniprot id: A0A1I7I0M8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

388950:A0W33 RS07050
gene id: 388950:A0W33_RS07050
uniprot id: A0A1I7IDE9
names: Similarity
messages: Belongs to the histone deacetylase family.

388950:A0W33 RS03710
gene id: 388950:A0W33_RS03710
uniprot id: A0A1I7JXN4
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

388950:A0W33 RS19595
gene id: 388950:A0W33_RS19595
uniprot id: A0A1I7G8S6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

388950:A0W33 RS01435
gene id: 388950:A0W33_RS01435
uniprot id: A0A1I7GQM4
names: Similarity
messages: Belongs to the isochorismate synthase family.

388950:A0W33 RS04760
gene id: 388950:A0W33_RS04760
uniprot id: A0A1I7K4C6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

388950:A0W33 RS12135
gene id: 388950:A0W33_RS12135
uniprot id: A0A1I7J977
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

388950:A0W33 RS15115
gene id: 388950:A0W33_RS15115
uniprot id: A0A1I7KGS1
names: Similarity
messages: Belongs to the type IA topoisomerase family.

388950:A0W33 RS18165
gene id: 388950:A0W33_RS18165
uniprot id: A0A1I7FXA9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

388950:A0W33 RS00760
gene id: 388950:A0W33_RS00760
uniprot id: A0A1I7GIV8
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

388950:A0W33 RS05715
gene id: 388950:A0W33_RS05715
uniprot id: A0A1I7K9K5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

388950:A0W33 RS12335
gene id: 388950:A0W33_RS12335
uniprot id: A0A1I7J7S6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

388950:A0W33 RS00290
gene id: 388950:A0W33_RS00290
uniprot id: A0A1I7GEL3
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

388950:A0W33 RS14810
gene id: 388950:A0W33_RS14810
uniprot id: A0A1I7KFH7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

388950:A0W33 RS03280
gene id: 388950:A0W33_RS03280
uniprot id: A0A1I7H6W9
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

388950:A0W33 RS10845
gene id: 388950:A0W33_RS10845
uniprot id: A0A1I7JHB8
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

388950:A0W33 RS02275
gene id: 388950:A0W33_RS02275
uniprot id: A0A1I7GYE5
names: Similarity
messages: Belongs to the sterol desaturase family.

388950:A0W33 RS10610
gene id: 388950:A0W33_RS10610
uniprot id: A0A1I7JIR3
names: Similarity
messages: Belongs to the peptidase M1 family.

388950:A0W33 RS05350
gene id: 388950:A0W33_RS05350
uniprot id: A0A1I7K7X4
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

388950:A0W33 RS02775
gene id: 388950:A0W33_RS02775
uniprot id: A0A1I7H318
names: Subcellular Location Annotation
messages: Membrane

388950:A0W33 RS06190
gene id: 388950:A0W33_RS06190
uniprot id: A0A1I7ILF0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

388950:A0W33 RS00795
gene id: 388950:A0W33_RS00795
uniprot id: A0A1I7GJC7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

388950:A0W33 RS14305
gene id: 388950:A0W33_RS14305
uniprot id: A0A1I7KXK3
names: Function
names: Similarity
messages: Belongs to the N-acylglucosamine 2-epimerase family.
messages: Belongs to the cellobiose 2-epimerase family.
messages: Catalyzes the reversible epimerization of cellobiose to 4-O-beta-D-glucopyranosyl-D-mannose (Glc-Man).

388950:A0W33 RS03265
gene id: 388950:A0W33_RS03265
uniprot id: A0A1I7H6M8
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

388950:A0W33 RS01700
gene id: 388950:A0W33_RS01700
uniprot id: A0A1I7GT10
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

388950:A0W33 RS03970
gene id: 388950:A0W33_RS03970
uniprot id: A0A1I7JZB8
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

388950:A0W33 RS01555
gene id: 388950:A0W33_RS01555
uniprot id: A0A1I7GS88
names: Similarity
messages: Belongs to the pirin family.

388950:A0W33 RS05415
gene id: 388950:A0W33_RS05415
uniprot id: A0A1I7K8C5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

388950:A0W33 RS17600
gene id: 388950:A0W33_RS17600
uniprot id: A0A1I7FRS8
names: Function
names: Similarity
messages: Belongs to the trehalose phosphatase family.
messages: Removes the phosphate from trehalose 6-phosphate to produce free trehalose.

388950:A0W33 RS05695
gene id: 388950:A0W33_RS05695
uniprot id: A0A1I7K9H9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

388950:A0W33 RS05740
gene id: 388950:A0W33_RS05740
uniprot id: A0A1I7K9Q6
names: Subcellular Location Annotation
messages: Membrane

388950:A0W33 RS17140
gene id: 388950:A0W33_RS17140
uniprot id: A0A1I7FMQ1
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

388950:A0W33 RS13830
gene id: 388950:A0W33_RS13830
uniprot id: A0A1I7KLF7
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

388950:A0W33 RS13995
gene id: 388950:A0W33_RS13995
uniprot id: A0A1I7KYL0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

388950:A0W33 RS09865
gene id: 388950:A0W33_RS09865
uniprot id: A0A1I7JNS1
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

388950:A0W33 RS18185
gene id: 388950:A0W33_RS18185
uniprot id: A0A1I7FXB9
names: Similarity
messages: Belongs to the Nudix hydrolase family.

388950:A0W33 RS18530
gene id: 388950:A0W33_RS18530
uniprot id: A0A1I7G0J6
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

388950:A0W33 RS13460
gene id: 388950:A0W33_RS13460
uniprot id: A0A1I7KMQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

388950:A0W33 RS09445
gene id: 388950:A0W33_RS09445
uniprot id: A0A1I7HSY2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

388950:A0W33 RS17915
gene id: 388950:A0W33_RS17915
uniprot id: A0A1I7FUW5
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

388950:A0W33 RS03990
gene id: 388950:A0W33_RS03990
uniprot id: A0A1I7JZC3
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family.

388950:A0W33 RS06520
gene id: 388950:A0W33_RS06520
uniprot id: A0A1I7IIB1
names: Subcellular Location Annotation
messages: Membrane

388950:A0W33 RS17190
gene id: 388950:A0W33_RS17190
uniprot id: A0A1I7FN01
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

388950:A0W33 RS14210
gene id: 388950:A0W33_RS14210
uniprot id: A0A1I7KV59
names: Subcellular Location Annotation
messages: Membrane

388950:A0W33 RS10200
gene id: 388950:A0W33_RS10200
uniprot id: A0A1I7JLL0
names: Subcellular Location Annotation
messages: Membrane

388950:A0W33 RS02800
gene id: 388950:A0W33_RS02800
uniprot id: A0A1I7H363
names: Similarity
messages: Belongs to the pirin family.

388950:A0W33 RS02345
gene id: 388950:A0W33_RS02345
uniprot id: A0A1I7GZQ6
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

388950:A0W33 RS02180
gene id: 388950:A0W33_RS02180
uniprot id: A0A1I7GY09
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

388950:A0W33 RS16570
gene id: 388950:A0W33_RS16570
uniprot id: A0A1I7FHQ1
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

388950:A0W33 RS04450
gene id: 388950:A0W33_RS04450
uniprot id: A0A1I7K289
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-stimulated subfamily.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Requires K(+) for maximal activity.
messages: Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na(+) movement across the membrane.

388950:A0W33 RS16880
gene id: 388950:A0W33_RS16880
uniprot id: A0A1I7FKK5
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.

388950:A0W33 RS17275
gene id: 388950:A0W33_RS17275
uniprot id: A0A1I7FNT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

388950:A0W33 RS08210
gene id: 388950:A0W33_RS08210
uniprot id: A0A1I7I3K1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

388950:A0W33 RS14710
gene id: 388950:A0W33_RS14710
uniprot id: A0A1I7KET2
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

388950:A0W33 RS01500
gene id: 388950:A0W33_RS01500
uniprot id: A0A1I7GR37
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urocanase family.
messages: Binds 1 NAD(+) per subunit.
messages: Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

388950:A0W33 RS11290
gene id: 388950:A0W33_RS11290
uniprot id: A0A1I7JED2
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

388950:A0W33 RS04025
gene id: 388950:A0W33_RS04025
uniprot id: A0A1I7JZJ4
names: Similarity
messages: Belongs to the glycosyl hydrolase 10 (cellulase F) family.

388950:A0W33 RS19065
gene id: 388950:A0W33_RS19065
uniprot id: A0A1I7G5B8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

388950:A0W33 RS03730
gene id: 388950:A0W33_RS03730
uniprot id: A0A1I7JY39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

388950:A0W33 RS10590
gene id: 388950:A0W33_RS10590
uniprot id: A0A1I7JIR2
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

388950:A0W33 RS01445
gene id: 388950:A0W33_RS01445
uniprot id: A0A1I7GQQ7
names: Subcellular Location Annotation
messages: Membrane

388950:A0W33 RS13685
gene id: 388950:A0W33_RS13685
uniprot id: A0A1I7KLL0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

388950:A0W33 RS19250
gene id: 388950:A0W33_RS19250
uniprot id: A0A1I7G6B2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Cytoplasm
messages: Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

388950:A0W33 RS03430
gene id: 388950:A0W33_RS03430
uniprot id: A0A1I7JWC9
names: Subcellular Location Annotation
messages: Membrane

388950:A0W33 RS08790
gene id: 388950:A0W33_RS08790
uniprot id: A0A1I7HY97
names: Subcellular Location Annotation
messages: Membrane

388950:A0W33 RS01325
gene id: 388950:A0W33_RS01325
uniprot id: A0A1I7GQ10
names: Similarity
messages: Belongs to the peptidase S13 family.

388950:A0W33 RS19010
gene id: 388950:A0W33_RS19010
uniprot id: A0A1I7G439
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

388950:A0W33 RS18030
gene id: 388950:A0W33_RS18030
uniprot id: A0A1I7FW40
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

388950:A0W33 RS06435
gene id: 388950:A0W33_RS06435
uniprot id: A0A1I7IJ18
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane
messages: Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins.

388950:A0W33 RS12880
gene id: 388950:A0W33_RS12880
uniprot id: A0A1I7J3G1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Membrane

388950:A0W33 RS11985
gene id: 388950:A0W33_RS11985
uniprot id: A0A1I7JAF4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

388950:A0W33 RS00235
gene id: 388950:A0W33_RS00235
uniprot id: A0A1I7GE69
names: Similarity
messages: Belongs to the AlaDH/PNT family.

388950:A0W33 RS04365
gene id: 388950:A0W33_RS04365
uniprot id: A0A1I7K1Q6
names: Subcellular Location Annotation
messages: Membrane

388950:A0W33 RS19555
gene id: 388950:A0W33_RS19555
uniprot id: A0A1I7G8F5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

388950:A0W33 RS13530
gene id: 388950:A0W33_RS13530
uniprot id: A0A1I7KM98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

388950:A0W33 RS12425
gene id: 388950:A0W33_RS12425
uniprot id: A0A1I7J6Y0
names: Subcellular Location Annotation
messages: Membrane

388950:A0W33 RS12825
gene id: 388950:A0W33_RS12825
uniprot id: A0A1I7J3X4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Membrane

388950:A0W33 RS04725
gene id: 388950:A0W33_RS04725
uniprot id: A0A1I7K3Y2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

388950:A0W33 RS10760
gene id: 388950:A0W33_RS10760
uniprot id: A0A1I7JHX3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

388950:A0W33 RS07035
gene id: 388950:A0W33_RS07035
uniprot id: A0A1I7IDI5
names: Similarity
messages: Belongs to the thiolase-like superfamily. Chalcone/stilbene synthases family.

388950:A0W33 RS10915
gene id: 388950:A0W33_RS10915
uniprot id: A0A1I7JGV1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

388950:A0W33 RS16550
gene id: 388950:A0W33_RS16550
uniprot id: A0A1I7FHQ5
names: Subcellular Location Annotation
messages: Membrane

388950:A0W33 RS09505
gene id: 388950:A0W33_RS09505
uniprot id: A0A1I7HRY3
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

388950:A0W33 RS05510
gene id: 388950:A0W33_RS05510
uniprot id: A0A1I7K8Q9
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

388950:A0W33 RS14480
gene id: 388950:A0W33_RS14480
uniprot id: A0A1I7KWY4
names: Subcellular Location Annotation
messages: Membrane

388950:A0W33 RS19345
gene id: 388950:A0W33_RS19345
uniprot id: A0A1I7G738
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

388950:A0W33 RS12930
gene id: 388950:A0W33_RS12930
uniprot id: A0A1I7J382
names: Function
names: Similarity
messages: Belongs to the TrhO family.
messages: Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.

388950:A0W33 RS19715
gene id: 388950:A0W33_RS19715
uniprot id: A0A1I7GA45
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

388950:A0W33 RS19880
gene id: 388950:A0W33_RS19880
uniprot id: A0A1I7GAZ8
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

388950:A0W33 RS02690
gene id: 388950:A0W33_RS02690
uniprot id: A0A1I7H2W1
names: Subcellular Location Annotation
messages: Membrane

388950:A0W33 RS04765
gene id: 388950:A0W33_RS04765
uniprot id: A0A1I7K4A6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

388950:A0W33 RS20390
gene id: 388950:A0W33_RS20390
uniprot id: A0A1I7KP35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VirD4/TraG family.
messages: Membrane

388950:A0W33 RS14295
gene id: 388950:A0W33_RS14295
uniprot id: A0A1I7KXS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

388950:A0W33 RS11070
gene id: 388950:A0W33_RS11070
uniprot id: A0A1I7JFW8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

388950:A0W33 RS06480
gene id: 388950:A0W33_RS06480
uniprot id: A0A1I7IIN2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

388950:A0W33 RS07540
gene id: 388950:A0W33_RS07540
uniprot id: A0A1I7I957
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

388950:A0W33 RS19160
gene id: 388950:A0W33_RS19160
uniprot id: A0A1I7G5M7
names: Subcellular Location Annotation
messages: Membrane

388950:A0W33 RS04115
gene id: 388950:A0W33_RS04115
uniprot id: A0A1I7JZX0
names: Subcellular Location Annotation
messages: Membrane

388950:A0W33 RS11460
gene id: 388950:A0W33_RS11460
uniprot id: A0A1I7JDH7
names: Similarity
messages: Belongs to the GARS family.

388950:A0W33 RS09500
gene id: 388950:A0W33_RS09500
uniprot id: A0A1I7HRR7
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

388950:A0W33 RS01390
gene id: 388950:A0W33_RS01390
uniprot id: A0A1I7GQ33
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LamB/PxpA family.
messages: Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
messages: Forms a complex composed of PxpA, PxpB and PxpC.

388950:A0W33 RS14920
gene id: 388950:A0W33_RS14920
uniprot id: A0A1I7KG58
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

388950:A0W33 RS18905
gene id: 388950:A0W33_RS18905
uniprot id: A0A1I7G3Q0
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

388950:A0W33 RS08475
gene id: 388950:A0W33_RS08475
uniprot id: A0A1I7I1S3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

388950:A0W33 RS04370
gene id: 388950:A0W33_RS04370
uniprot id: A0A1I7K1P0
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

388950:A0W33 RS18310
gene id: 388950:A0W33_RS18310
uniprot id: A0A1I7FYH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

388950:A0W33 RS09195
gene id: 388950:A0W33_RS09195
uniprot id: A0A1I7HUQ7
names: Subcellular Location Annotation
messages: Membrane

388950:A0W33 RS03220
gene id: 388950:A0W33_RS03220
uniprot id: A0A1I7H6C3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

388950:A0W33 RS19910
gene id: 388950:A0W33_RS19910
uniprot id: A0A1I7GBT6
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

388950:A0W33 RS10660
gene id: 388950:A0W33_RS10660
uniprot id: A0A1I7JIJ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

388950:A0W33 RS01375
gene id: 388950:A0W33_RS01375
uniprot id: A0A1I7GPW4
names: Subcellular Location Annotation
messages: Membrane

388950:A0W33 RS11030
gene id: 388950:A0W33_RS11030
uniprot id: A0A1I7JG24
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

388950:A0W33 RS01235
gene id: 388950:A0W33_RS01235
uniprot id: A0A1I7GNI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

388950:A0W33 RS05380
gene id: 388950:A0W33_RS05380
uniprot id: A0A1I7K879
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

388950:A0W33 RS02390
gene id: 388950:A0W33_RS02390
uniprot id: A0A1I7GZI8
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

388950:A0W33 RS02995
gene id: 388950:A0W33_RS02995
uniprot id: A0A1I7H4S3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.
messages: In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: In the N-terminal section; belongs to the MIP18 family.

388950:A0W33 RS07975
gene id: 388950:A0W33_RS07975
uniprot id: A0A1I7I5N4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

388950:A0W33 RS15445
gene id: 388950:A0W33_RS15445
uniprot id: A0A1I7KIN4
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.

388950:A0W33 RS06180
gene id: 388950:A0W33_RS06180
uniprot id: A0A1I7ILN8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

388950:A0W33 RS12685
gene id: 388950:A0W33_RS12685
uniprot id: A0A1I7J542
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

388950:A0W33 RS13590
gene id: 388950:A0W33_RS13590
uniprot id: A0A1I7KM63
names: Similarity
messages: Belongs to the DEAD box helicase family.

388950:A0W33 RS07610
gene id: 388950:A0W33_RS07610
uniprot id: A0A1I7I8H3
names: Similarity
messages: Belongs to the peptidase S9A family.

388950:A0W33 RS12765
gene id: 388950:A0W33_RS12765
uniprot id: A0A1I7J4H8
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

388950:A0W33 RS06290
gene id: 388950:A0W33_RS06290
uniprot id: A0A1I7IKN0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

388950:A0W33 RS19950
gene id: 388950:A0W33_RS19950
uniprot id: A0A1I7GC56
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

388950:A0W33 RS17860
gene id: 388950:A0W33_RS17860
uniprot id: A0A1I7FU97
names: Similarity
messages: Belongs to the citrate synthase family.

388950:A0W33 RS02620
gene id: 388950:A0W33_RS02620
uniprot id: A0A1I7H1Q5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: Homotrimer.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.

388950:A0W33 RS16235
gene id: 388950:A0W33_RS16235
uniprot id: A0A1I7FEQ7
names: Similarity
messages: In the C-terminal section; belongs to the complex I 49 kDa subunit family.

388950:A0W33 RS16000
gene id: 388950:A0W33_RS16000
uniprot id: A0A1I7KT41
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

388950:A0W33 RS02210
gene id: 388950:A0W33_RS02210
uniprot id: A0A1I7GXQ8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

388950:A0W33 RS17340
gene id: 388950:A0W33_RS17340
uniprot id: A0A1I7FPA0
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

388950:A0W33 RS05060
gene id: 388950:A0W33_RS05060
uniprot id: A0A1I7K632
names: Subcellular Location Annotation
messages: Membrane

388950:A0W33 RS00985
gene id: 388950:A0W33_RS00985
uniprot id: A0A1I7GL24
names: Subcellular Location Annotation
messages: Membrane

388950:A0W33 RS10400
gene id: 388950:A0W33_RS10400
uniprot id: A0A1I7JK45
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

388950:A0W33 RS02265
gene id: 388950:A0W33_RS02265
uniprot id: A0A1I7GYB9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

388950:A0W33 RS10655
gene id: 388950:A0W33_RS10655
uniprot id: A0A1I7JIJ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

388950:A0W33 RS06385
gene id: 388950:A0W33_RS06385
uniprot id: A0A1I7IJG9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

388950:A0W33 RS16560
gene id: 388950:A0W33_RS16560
uniprot id: A0A1I7FHT8
names: Similarity
messages: Belongs to the DEAD box helicase family.

388950:A0W33 RS18540
gene id: 388950:A0W33_RS18540
uniprot id: A0A1I7G076
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

388950:A0W33 RS05400
gene id: 388950:A0W33_RS05400
uniprot id: A0A1I7K8C1
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

388950:A0W33 RS16185
gene id: 388950:A0W33_RS16185
uniprot id: A0A1I7FDZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

388950:A0W33 RS19765
gene id: 388950:A0W33_RS19765
uniprot id: A0A1I7GA24
names: Similarity
messages: Belongs to the DapB family.

388950:A0W33 RS00475
gene id: 388950:A0W33_RS00475
uniprot id: A0A1I7GGQ8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Binds 1 copper ion per subunit, denoted as copper B.
messages: Binds 2 heme groups per subunit, denoted as high- and low-spin.
messages: Membrane

388950:A0W33 RS16210
gene id: 388950:A0W33_RS16210
uniprot id: A0A1I7FEF8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

388950:A0W33 RS08200
gene id: 388950:A0W33_RS08200
uniprot id: A0A1I7I3N8
names: Similarity
messages: Belongs to the LacAB/RpiB family.

388950:A0W33 RS16850
gene id: 388950:A0W33_RS16850
uniprot id: A0A1I7FK71
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

388950:A0W33 RS04470
gene id: 388950:A0W33_RS04470
uniprot id: A0A1I7K2E0
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.

388950:A0W33 RS10785
gene id: 388950:A0W33_RS10785
uniprot id: A0A1I7JHP7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

388950:A0W33 RS14595
gene id: 388950:A0W33_RS14595
uniprot id: A0A1I7KE79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0394 family.
messages: Membrane

388950:A0W33 RS02310
gene id: 388950:A0W33_RS02310
uniprot id: A0A1I7GZ12
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

388950:A0W33 RS10755
gene id: 388950:A0W33_RS10755
uniprot id: A0A1I7JHY3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

388950:A0W33 RS01925
gene id: 388950:A0W33_RS01925
uniprot id: A0A1I7GUW6
names: Cofactor
names: Similarity
messages: Belongs to the nitroreductase family.
messages: Binds 1 FMN per subunit.

388950:A0W33 RS15000
gene id: 388950:A0W33_RS15000
uniprot id: A0A1I7KG99
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

388950:A0W33 RS12155
gene id: 388950:A0W33_RS12155
uniprot id: A0A1I7J944
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

388950:A0W33 RS13670
gene id: 388950:A0W33_RS13670
uniprot id: A0A1I7KLY5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

388950:A0W33 RS18550
gene id: 388950:A0W33_RS18550
uniprot id: A0A1I7G0P9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

388950:A0W33 RS07465
gene id: 388950:A0W33_RS07465
uniprot id: A0A1I7IA53
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

388950:A0W33 RS15045
gene id: 388950:A0W33_RS15045
uniprot id: A0A1I7KGJ2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
messages: Cytoplasm

388950:A0W33 RS17825
gene id: 388950:A0W33_RS17825
uniprot id: A0A1I7FTT5
names: Caution
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IcmF family.
messages: Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly.
messages: Homodimer.
messages: Is composed of four functional domains: the N-terminal 5'-deoxyadenosylcobalamin binding region that is homologous to the small subunit of ICM (IcmB), a middle P-loop GTPase domain (MeaI) that likely acts as a chaperone for ICM, a structured linker region involved in dimer formation, and a C-terminal part that is homologous to the large substrate-binding subunit of ICM (IcmA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

388950:A0W33 RS17005
gene id: 388950:A0W33_RS17005
uniprot id: A0A1I7FLH2
names: Function
messages: Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.

388950:A0W33 RS02435
gene id: 388950:A0W33_RS02435
uniprot id: A0A1I7GZX7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

388950:A0W33 RS17360
gene id: 388950:A0W33_RS17360
uniprot id: A0A1I7FPG3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

388950:A0W33 RS11585
gene id: 388950:A0W33_RS11585
uniprot id: A0A1I7JCL9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. GalK subfamily.
messages: Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P).
messages: Cytoplasm

388950:A0W33 RS16725
gene id: 388950:A0W33_RS16725
uniprot id: A0A1I7FJ75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Membrane

388950:A0W33 RS07385
gene id: 388950:A0W33_RS07385
uniprot id: A0A1I7IAR0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

388950:A0W33 RS02000
gene id: 388950:A0W33_RS02000
uniprot id: A0A1I7GVN7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

388950:A0W33 RS17835
gene id: 388950:A0W33_RS17835
uniprot id: A0A1I7FTZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

388950:A0W33 RS09840
gene id: 388950:A0W33_RS09840
uniprot id: A0A1I7JNV7
names: Subcellular Location Annotation
messages: Membrane

388950:A0W33 RS07225
gene id: 388950:A0W33_RS07225
uniprot id: A0A1I7ICI4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the adenylate cyclase family. DacA/CdaA subfamily.
messages: Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably a homodimer.

388950:A0W33 RS15850
gene id: 388950:A0W33_RS15850
uniprot id: A0A1I7KTL7
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

388950:A0W33 RS17070
gene id: 388950:A0W33_RS17070
uniprot id: A0A1I7FMJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

388950:A0W33 RS06380
gene id: 388950:A0W33_RS06380
uniprot id: A0A1I7IJL6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

388950:A0W33 RS15620
gene id: 388950:A0W33_RS15620
uniprot id: A0A1I7KW68
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HemJ family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Catalyzes the oxidation of protoporphyrinogen IX to protoporphyrin IX.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

388950:A0W33 RS15330
gene id: 388950:A0W33_RS15330
uniprot id: A0A1I7KI91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YejK family.
messages: nucleoid

388950:A0W33 RS18825
gene id: 388950:A0W33_RS18825
uniprot id: A0A1I7G2P3
names: Subunit
messages: Homodimer.

388950:A0W33 RS07945
gene id: 388950:A0W33_RS07945
uniprot id: A0A1I7I5V3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

388950:A0W33 RS10055
gene id: 388950:A0W33_RS10055
uniprot id: A0A1I7JMF9
names: Similarity
messages: Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.

388950:A0W33 RS04600
gene id: 388950:A0W33_RS04600
uniprot id: A0A1I7K377
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

388950:A0W33 RS00365
gene id: 388950:A0W33_RS00365
uniprot id: A0A1I7GFH7
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

388950:A0W33 RS14590
gene id: 388950:A0W33_RS14590
uniprot id: A0A1I7KE31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0394 family.
messages: Membrane

388950:A0W33 RS12305
gene id: 388950:A0W33_RS12305
uniprot id: A0A1I7J7Z2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

388950:A0W33 RS12775
gene id: 388950:A0W33_RS12775
uniprot id: A0A1I7J4C9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

388950:A0W33 RS06780
gene id: 388950:A0W33_RS06780
uniprot id: A0A1I7IFQ7
names: Similarity
messages: Belongs to the UPF0234 family.

388950:A0W33 RS00260
gene id: 388950:A0W33_RS00260
uniprot id: A0A1I7GEB3
names: Subcellular Location Annotation
messages: Membrane

388950:A0W33 RS05670
gene id: 388950:A0W33_RS05670
uniprot id: A0A1I7K9J9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

388950:A0W33 RS11240
gene id: 388950:A0W33_RS11240
uniprot id: A0A1I7JEP4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

388950:A0W33 RS18170
gene id: 388950:A0W33_RS18170
uniprot id: A0A1I7FXF3
names: Similarity
messages: Belongs to the Nudix hydrolase family.

388950:A0W33 RS12740
gene id: 388950:A0W33_RS12740
uniprot id: A0A1I7J4L9
names: Similarity
messages: Belongs to the pyruvate kinase family.

388950:A0W33 RS12505
gene id: 388950:A0W33_RS12505
uniprot id: A0A1I7J6J0
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).

388950:A0W33 RS07560
gene id: 388950:A0W33_RS07560
uniprot id: A0A1I7I903
names: Similarity
messages: Belongs to the heat shock protein 90 family.

388950:A0W33 RS19670
gene id: 388950:A0W33_RS19670
uniprot id: A0A1I7G963
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

388950:A0W33 RS12380
gene id: 388950:A0W33_RS12380
uniprot id: A0A1I7J7E1
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

388950:A0W33 RS00375
gene id: 388950:A0W33_RS00375
uniprot id: A0A1I7GFN3
names: Subcellular Location Annotation
messages: Membrane

388950:A0W33 RS08855
gene id: 388950:A0W33_RS08855
uniprot id: A0A1I7HXY5
names: Caution
names: Function
names: Similarity
messages: Belongs to the GGGP/HepGP synthase family. Group II subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P).

388950:A0W33 RS19435
gene id: 388950:A0W33_RS19435
uniprot id: A0A1I7G7N2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

388950:A0W33 RS10265
gene id: 388950:A0W33_RS10265
uniprot id: A0A1I7JL29
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

388950:A0W33 RS02150
gene id: 388950:A0W33_RS02150
uniprot id: A0A1I7GX51
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

388950:A0W33 RS04620
gene id: 388950:A0W33_RS04620
uniprot id: A0A1I7K3C1
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

388950:A0W33 RS20650
gene id: 388950:A0W33_RS20650
uniprot id: A0A1I7JHL7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

388950:A0W33 RS13935
gene id: 388950:A0W33_RS13935
uniprot id: A0A1I7KKP0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

388950:A0W33 RS19665
gene id: 388950:A0W33_RS19665
uniprot id: A0A1I7G964
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

388950:A0W33 RS17050
gene id: 388950:A0W33_RS17050
uniprot id: A0A1I7FM07
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

388950:A0W33 RS19310
gene id: 388950:A0W33_RS19310
uniprot id: A0A1I7G6T5
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.
messages: Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

388950:A0W33 RS03985
gene id: 388950:A0W33_RS03985
uniprot id: A0A1I7JZB1
names: Subcellular Location Annotation
messages: Membrane

388950:A0W33 RS08930
gene id: 388950:A0W33_RS08930
uniprot id: A0A1I7HX58
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

388950:A0W33 RS06275
gene id: 388950:A0W33_RS06275
uniprot id: A0A1I7IKQ1
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

388950:A0W33 RS12640
gene id: 388950:A0W33_RS12640
uniprot id: A0A1I7J5N7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

388950:A0W33 RS15570
gene id: 388950:A0W33_RS15570
uniprot id: A0A1I7KW06
names: Subcellular Location Annotation
messages: Membrane

388950:A0W33 RS08260
gene id: 388950:A0W33_RS08260
uniprot id: A0A1I7I348
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

388950:A0W33 RS19945
gene id: 388950:A0W33_RS19945
uniprot id: A0A1I7GBJ1
names: Subcellular Location Annotation
messages: Membrane

388950:A0W33 RS18670
gene id: 388950:A0W33_RS18670
uniprot id: A0A1I7G1A6
names: Similarity
messages: Belongs to the DEAD box helicase family.

388950:A0W33 RS10700
gene id: 388950:A0W33_RS10700
uniprot id: A0A1I7JI86
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

388950:A0W33 RS02420
gene id: 388950:A0W33_RS02420
uniprot id: A0A1I7GZW1
names: Similarity
messages: Belongs to the catalase family.

388950:A0W33 RS05745
gene id: 388950:A0W33_RS05745
uniprot id: A0A1I7K9U5
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

388950:A0W33 RS03425
gene id: 388950:A0W33_RS03425
uniprot id: A0A1I7JWB0
names: Subcellular Location Annotation
messages: Membrane

388950:A0W33 RS02505
gene id: 388950:A0W33_RS02505
uniprot id: A0A1I7H0N5
names: Function
messages: May be involved in the biogenesis of curli organelles.

388950:A0W33 RS11965
gene id: 388950:A0W33_RS11965
uniprot id: A0A1I7JAE6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

388950:A0W33 RS14780
gene id: 388950:A0W33_RS14780
uniprot id: A0A1I7KF63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0316 family.
messages: Cell membrane
messages: Membrane

388950:A0W33 RS16835
gene id: 388950:A0W33_RS16835
uniprot id: A0A1I7FK54
names: Subcellular Location Annotation
messages: Membrane

388950:A0W33 RS08820
gene id: 388950:A0W33_RS08820
uniprot id: A0A1I7HXY3
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

388950:A0W33 RS01035
gene id: 388950:A0W33_RS01035
uniprot id: A0A1I7GLG2
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

388950:A0W33 RS02900
gene id: 388950:A0W33_RS02900
uniprot id: A0A1I7H460
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

388950:A0W33 RS13365
gene id: 388950:A0W33_RS13365
uniprot id: A0A1I7IZX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Cytoplasm

388950:A0W33 RS10685
gene id: 388950:A0W33_RS10685
uniprot id: A0A1I7JIE1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

388950:A0W33 RS14350
gene id: 388950:A0W33_RS14350
uniprot id: A0A1I7KXI8
names: Similarity
messages: Belongs to the glycosyl hydrolase 9 (cellulase E) family.

388950:A0W33 RS13375
gene id: 388950:A0W33_RS13375
uniprot id: A0A1I7J018
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

388950:A0W33 RS02165
gene id: 388950:A0W33_RS02165
uniprot id: A0A1I7GXD4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

388950:A0W33 RS17900
gene id: 388950:A0W33_RS17900
uniprot id: A0A1I7FUP4
names: Function
names: Similarity
names: Subunit
messages: Catalyzes the ATP-dependent polymerization of arginine and aspartate to multi-L-arginyl-poly-L-aspartic acid (cyanophycin; a water-insoluble reserve polymer).
messages: Homodimer.
messages: In the C-terminal section; belongs to the MurCDEF family.

388950:A0W33 RS08830
gene id: 388950:A0W33_RS08830
uniprot id: A0A1I7HXW5
names: Subcellular Location Annotation
messages: Membrane

388950:A0W33 RS00790
gene id: 388950:A0W33_RS00790
uniprot id: A0A1I7GJ75
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

388950:A0W33 RS17655
gene id: 388950:A0W33_RS17655
uniprot id: A0A1I7FS71
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

388950:A0W33 RS07495
gene id: 388950:A0W33_RS07495
uniprot id: A0A1I7I9L1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

388950:A0W33 RS07625
gene id: 388950:A0W33_RS07625
uniprot id: A0A1I7I8D4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

388950:A0W33 RS13990
gene id: 388950:A0W33_RS13990
uniprot id: A0A1I7KXY2
names: Subcellular Location Annotation
messages: Cell inner membrane

388950:A0W33 RS10975
gene id: 388950:A0W33_RS10975
uniprot id: A0A1I7JGH5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

388950:A0W33 RS00755
gene id: 388950:A0W33_RS00755
uniprot id: A0A1I7GJ00
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

388950:A0W33 RS04425
gene id: 388950:A0W33_RS04425
uniprot id: A0A1I7K278
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

388950:A0W33 RS19690
gene id: 388950:A0W33_RS19690
uniprot id: A0A1I7G9P6
names: Function
names: Similarity
messages: Belongs to the catalase family. HPII subfamily.
messages: Serves to protect cells from the toxic effects of hydrogen peroxide.

388950:A0W33 RS03490
gene id: 388950:A0W33_RS03490
uniprot id: A0A1I7JWN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

388950:A0W33 RS06985
gene id: 388950:A0W33_RS06985
uniprot id: A0A1I7IDX8
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

388950:A0W33 RS06700
gene id: 388950:A0W33_RS06700
uniprot id: A0A1I7IGI7
names: Subcellular Location Annotation
messages: Membrane

388950:A0W33 RS10300
gene id: 388950:A0W33_RS10300
uniprot id: A0A1I7JKZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

388950:A0W33 RS08105
gene id: 388950:A0W33_RS08105
uniprot id: A0A1I7I4H7
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

388950:A0W33 RS11795
gene id: 388950:A0W33_RS11795
uniprot id: A0A1I7JBF2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

388950:A0W33 RS04015
gene id: 388950:A0W33_RS04015
uniprot id: A0A1I7JZG9
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 67 family.
messages: Homodimer.

388950:A0W33 RS10710
gene id: 388950:A0W33_RS10710
uniprot id: A0A1I7JIA0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

388950:A0W33 RS11175
gene id: 388950:A0W33_RS11175
uniprot id: A0A1I7JF93
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueG family.
messages: Binds 2 [4Fe-4S] clusters per monomer.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

388950:A0W33 RS06245
gene id: 388950:A0W33_RS06245
uniprot id: A0A1I7IL27
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

388950:A0W33 RS01995
gene id: 388950:A0W33_RS01995
uniprot id: A0A1I7GVI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

388950:A0W33 RS11725
gene id: 388950:A0W33_RS11725
uniprot id: A0A1I7JBU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

388950:A0W33 RS08730
gene id: 388950:A0W33_RS08730
uniprot id: A0A1I7HYN1
names: Subcellular Location Annotation
messages: Membrane

388950:A0W33 RS00575
gene id: 388950:A0W33_RS00575
uniprot id: A0A1I7GHH3
names: Subcellular Location Annotation
messages: Membrane

388950:A0W33 RS04795
gene id: 388950:A0W33_RS04795
uniprot id: A0A1I7K4J8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase Y family.
messages: Cell membrane
messages: Endoribonuclease that initiates mRNA decay.

388950:A0W33 RS02595
gene id: 388950:A0W33_RS02595
uniprot id: A0A1I7H1P7
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

388950:A0W33 RS19820
gene id: 388950:A0W33_RS19820
uniprot id: A0A1I7GAF6
names: Function
names: Similarity
names: Subunit
messages: Catalyzes the ATP-dependent polymerization of arginine and aspartate to multi-L-arginyl-poly-L-aspartic acid (cyanophycin; a water-insoluble reserve polymer).
messages: Homodimer.
messages: In the C-terminal section; belongs to the MurCDEF family.

388950:A0W33 RS02635
gene id: 388950:A0W33_RS02635
uniprot id: A0A1I7H1V0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

388950:A0W33 RS04120
gene id: 388950:A0W33_RS04120
uniprot id: A0A1I7K029
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

388950:A0W33 RS19640
gene id: 388950:A0W33_RS19640
uniprot id: A0A1I7G8Z3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

388950:A0W33 RS04640
gene id: 388950:A0W33_RS04640
uniprot id: A0A1I7K3G0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

388950:A0W33 RS10645
gene id: 388950:A0W33_RS10645
uniprot id: A0A1I7JIM0
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

388950:A0W33 RS02090
gene id: 388950:A0W33_RS02090
uniprot id: A0A1I7GWK4
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

388950:A0W33 RS08710
gene id: 388950:A0W33_RS08710
uniprot id: A0A1I7HYV7
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

388950:A0W33 RS00015
gene id: 388950:A0W33_RS00015
uniprot id: A0A1I7GBZ4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

388950:A0W33 RS01170
gene id: 388950:A0W33_RS01170
uniprot id: A0A1I7GND4
names: Subcellular Location Annotation
messages: Membrane

388950:A0W33 RS10815
gene id: 388950:A0W33_RS10815
uniprot id: A0A1I7JHH1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

388950:A0W33 RS09140
gene id: 388950:A0W33_RS09140
uniprot id: A0A1I7HV23
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

388950:A0W33 RS02470
gene id: 388950:A0W33_RS02470
uniprot id: A0A1I7H0B0
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

388950:A0W33 RS12625
gene id: 388950:A0W33_RS12625
uniprot id: A0A1I7J5H4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

388950:A0W33 RS01745
gene id: 388950:A0W33_RS01745
uniprot id: A0A1I7GTV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

388950:A0W33 RS16150
gene id: 388950:A0W33_RS16150
uniprot id: A0A1I7KS96
names: Subcellular Location Annotation
messages: Membrane

388950:A0W33 RS00830
gene id: 388950:A0W33_RS00830
uniprot id: A0A1I7GK32
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

388950:A0W33 RS00740
gene id: 388950:A0W33_RS00740
uniprot id: A0A1I7GIY1
names: Subcellular Location Annotation
messages: Membrane

388950:A0W33 RS09475
gene id: 388950:A0W33_RS09475
uniprot id: A0A1I7HS44
names: Similarity
messages: Belongs to the homogentisate dioxygenase family.

388950:A0W33 RS19485
gene id: 388950:A0W33_RS19485
uniprot id: A0A1I7G7Z8
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Feedback inhibited by histidine.

388950:A0W33 RS15095
gene id: 388950:A0W33_RS15095
uniprot id: A0A1I7KGM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

388950:A0W33 RS01715
gene id: 388950:A0W33_RS01715
uniprot id: A0A1I7GT30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

388950:A0W33 RS12205
gene id: 388950:A0W33_RS12205
uniprot id: A0A1I7J8S1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

388950:A0W33 RS14880
gene id: 388950:A0W33_RS14880
uniprot id: A0A1I7KFU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VKOR family.
messages: Membrane

388950:A0W33 RS15595
gene id: 388950:A0W33_RS15595
uniprot id: A0A1I7KW41
names: Subcellular Location Annotation
messages: Membrane

388950:A0W33 RS10830
gene id: 388950:A0W33_RS10830
uniprot id: A0A1I7JHF9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

388950:A0W33 RS13640
gene id: 388950:A0W33_RS13640
uniprot id: A0A1I7KLU7
names: Subcellular Location Annotation
messages: Membrane

388950:A0W33 RS15460
gene id: 388950:A0W33_RS15460
uniprot id: A0A1I7KIS8
names: Subcellular Location Annotation
messages: Periplasm

388950:A0W33 RS10350
gene id: 388950:A0W33_RS10350
uniprot id: A0A1I7JKG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

388950:A0W33 RS13485
gene id: 388950:A0W33_RS13485
uniprot id: A0A1I7KMF9
names: Function
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
messages: Catalyzes two reactions in de novo purine nucleotide biosynthesis. Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate.

388950:A0W33 RS09250
gene id: 388950:A0W33_RS09250
uniprot id: A0A1I7HTX9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the kynureninase family.
messages: Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

388950:A0W33 RS00850
gene id: 388950:A0W33_RS00850
uniprot id: A0A1I7GJR6
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

388950:A0W33 RS09270
gene id: 388950:A0W33_RS09270
uniprot id: A0A1I7HTR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

388950:A0W33 RS07960
gene id: 388950:A0W33_RS07960
uniprot id: A0A1I7I5S2
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

388950:A0W33 RS02695
gene id: 388950:A0W33_RS02695
uniprot id: A0A1I7H2E8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

388950:A0W33 RS02855
gene id: 388950:A0W33_RS02855
uniprot id: A0A1I7H3J0
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

388950:A0W33 RS07115
gene id: 388950:A0W33_RS07115
uniprot id: A0A1I7ICU9
names: Subcellular Location Annotation
messages: Membrane

388950:A0W33 RS12680
gene id: 388950:A0W33_RS12680
uniprot id: A0A1I7J596
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

388950:A0W33 RS04245
gene id: 388950:A0W33_RS04245
uniprot id: A0A1I7K136
names: Similarity
messages: Belongs to the peptidase S41A family.

388950:A0W33 RS10705
gene id: 388950:A0W33_RS10705
uniprot id: A0A1I7JI57
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

388950:A0W33 RS18515
gene id: 388950:A0W33_RS18515
uniprot id: A0A1I7FZY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

388950:A0W33 RS02370
gene id: 388950:A0W33_RS02370
uniprot id: A0A1I7GZC7
names: Subcellular Location Annotation
messages: Membrane

388950:A0W33 RS09025
gene id: 388950:A0W33_RS09025
uniprot id: A0A1I7HWH1
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

388950:A0W33 RS18860
gene id: 388950:A0W33_RS18860
uniprot id: A0A1I7G304
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

388950:A0W33 RS19480
gene id: 388950:A0W33_RS19480
uniprot id: A0A1I7G7X7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

388950:A0W33 RS05635
gene id: 388950:A0W33_RS05635
uniprot id: A0A1I7K9G0
names: Similarity
messages: Belongs to the Nth/MutY family.

388950:A0W33 RS14775
gene id: 388950:A0W33_RS14775
uniprot id: A0A1I7KF87
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

388950:A0W33 RS12495
gene id: 388950:A0W33_RS12495
uniprot id: A0A1I7J6D9
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

388950:A0W33 RS00725
gene id: 388950:A0W33_RS00725
uniprot id: A0A1I7GIS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

388950:A0W33 RS02645
gene id: 388950:A0W33_RS02645
uniprot id: A0A1I7H1Z2
names: Similarity
messages: Belongs to the DEAD box helicase family.

388950:A0W33 RS15860
gene id: 388950:A0W33_RS15860
uniprot id: A0A1I7KTG1
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

388950:A0W33 RS14490
gene id: 388950:A0W33_RS14490
uniprot id: A0A1I7KX25
names: Subcellular Location Annotation
messages: Membrane

388950:A0W33 RS00425
gene id: 388950:A0W33_RS00425
uniprot id: A0A1I7GG91
names: Similarity
names: Subunit
messages: Belongs to the multicopper oxidase family.
messages: Homotrimer.

388950:A0W33 RS10220
gene id: 388950:A0W33_RS10220
uniprot id: A0A1I7JLD4
names: Subcellular Location Annotation
messages: Membrane

388950:A0W33 RS20495
gene id: 388950:A0W33_RS20495
uniprot id: A0A1I7KPQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Membrane

388950:A0W33 RS12875
gene id: 388950:A0W33_RS12875
uniprot id: A0A1I7J3F0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

388950:A0W33 RS16205
gene id: 388950:A0W33_RS16205
uniprot id: A0A1I7FEC4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

388950:A0W33 RS05420
gene id: 388950:A0W33_RS05420
uniprot id: A0A1I7K8G4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

388950:A0W33 RS07450
gene id: 388950:A0W33_RS07450
uniprot id: A0A1I7IA98
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

388950:A0W33 RS19185
gene id: 388950:A0W33_RS19185
uniprot id: A0A1I7G5R1
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

388950:A0W33 RS17495
gene id: 388950:A0W33_RS17495
uniprot id: A0A1I7FQQ0
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.
messages: Belongs to the spermidine/spermine synthase family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Heterotetramer of two alpha and two beta chains arranged as a dimer of alpha/beta heterodimers.
messages: Homodimer or homotetramer.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain.

388950:A0W33 RS06540
gene id: 388950:A0W33_RS06540
uniprot id: A0A1I7II60
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the selenophosphate synthase 1 family. Class I subfamily.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Homodimer.
messages: Synthesizes selenophosphate from selenide and ATP.

388950:A0W33 RS19790
gene id: 388950:A0W33_RS19790
uniprot id: A0A1I7GAB6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

388950:A0W33 RS19635
gene id: 388950:A0W33_RS19635
uniprot id: A0A1I7G8Z2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

388950:A0W33 RS14890
gene id: 388950:A0W33_RS14890
uniprot id: A0A1I7KFP3
names: Similarity
messages: Belongs to the manganese catalase family.

388950:A0W33 RS17940
gene id: 388950:A0W33_RS17940
uniprot id: A0A1I7FV45
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

388950:A0W33 RS17520
gene id: 388950:A0W33_RS17520
uniprot id: A0A1I7FR07
names: Similarity
messages: Belongs to the peptidase S8 family.

388950:A0W33 RS08755
gene id: 388950:A0W33_RS08755
uniprot id: A0A1I7HYN8
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

388950:A0W33 RS12040
gene id: 388950:A0W33_RS12040
uniprot id: A0A1I7J9U4
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

388950:A0W33 RS19275
gene id: 388950:A0W33_RS19275
uniprot id: A0A1I7G6Q6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

388950:A0W33 RS07965
gene id: 388950:A0W33_RS07965
uniprot id: A0A1I7I5N7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

388950:A0W33 RS17270
gene id: 388950:A0W33_RS17270
uniprot id: A0A1I7FNR2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

388950:A0W33 RS01765
gene id: 388950:A0W33_RS01765
uniprot id: A0A1I7GTH7
names: Similarity
messages: Belongs to the pirin family.

388950:A0W33 RS14010
gene id: 388950:A0W33_RS14010
uniprot id: A0A1I7KVD5
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

388950:A0W33 RS18730
gene id: 388950:A0W33_RS18730
uniprot id: A0A1I7G201
names: Subcellular Location Annotation
messages: Membrane

388950:A0W33 RS09710
gene id: 388950:A0W33_RS09710
uniprot id: A0A1I7HQ30
names: Subunit
messages: Monomer.

388950:A0W33 RS01045
gene id: 388950:A0W33_RS01045
uniprot id: A0A1I7GLL1
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

388950:A0W33 RS02585
gene id: 388950:A0W33_RS02585
uniprot id: A0A1I7H1L8
names: Subcellular Location Annotation
messages: Membrane

388950:A0W33 RS16765
gene id: 388950:A0W33_RS16765
uniprot id: A0A1I7FJN6
names: Similarity
messages: Belongs to the AHA1 family.

388950:A0W33 RS12285
gene id: 388950:A0W33_RS12285
uniprot id: A0A1I7J853
names: Similarity
messages: Belongs to the SusD family.

388950:A0W33 RS08245
gene id: 388950:A0W33_RS08245
uniprot id: A0A1I7I3P2
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

388950:A0W33 RS20170
gene id: 388950:A0W33_RS20170
uniprot id: A0A1I7KQY2
names: Similarity
messages: Belongs to the NtaA/SnaA/DszA monooxygenase family.

388950:A0W33 RS06575
gene id: 388950:A0W33_RS06575
uniprot id: A0A1I7IHW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

388950:A0W33 RS10420
gene id: 388950:A0W33_RS10420
uniprot id: A0A1I7JK40
names: Similarity
messages: Belongs to the phosphosulfolactate synthase family.

388950:A0W33 RS05410
gene id: 388950:A0W33_RS05410
uniprot id: A0A1I7K8G5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

388950:A0W33 RS01285
gene id: 388950:A0W33_RS01285
uniprot id: A0A1I7GNX6
names: Subcellular Location Annotation
messages: Membrane

388950:A0W33 RS14785
gene id: 388950:A0W33_RS14785
uniprot id: A0A1I7KFE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

388950:A0W33 RS12280
gene id: 388950:A0W33_RS12280
uniprot id: A0A1I7J841
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

388950:A0W33 RS12460
gene id: 388950:A0W33_RS12460
uniprot id: A0A1I7J6N4
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.

388950:A0W33 RS13110
gene id: 388950:A0W33_RS13110
uniprot id: A0A1I7J203
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the etk/wzc family.
messages: Cell inner membrane
messages: Membrane

388950:A0W33 RS19440
gene id: 388950:A0W33_RS19440
uniprot id: A0A1I7G7P1
names: Similarity
messages: Belongs to the TrpF family.

388950:A0W33 RS19695
gene id: 388950:A0W33_RS19695
uniprot id: A0A1I7G9F6
names: Similarity
messages: Belongs to the deoxyhypusine synthase family.

388950:A0W33 RS17205
gene id: 388950:A0W33_RS17205
uniprot id: A0A1I7FN93
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

388950:A0W33 RS15040
gene id: 388950:A0W33_RS15040
uniprot id: A0A1I7KGF9
names: Similarity
messages: Belongs to the PAPS reductase family. CysD subfamily.

388950:A0W33 RS06080
gene id: 388950:A0W33_RS06080
uniprot id: A0A1I7IMF6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

388950:A0W33 RS17725
gene id: 388950:A0W33_RS17725
uniprot id: A0A1I7FT14
names: Subcellular Location Annotation
messages: Membrane

388950:A0W33 RS09115
gene id: 388950:A0W33_RS09115
uniprot id: A0A1I7HW15
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

388950:A0W33 RS00845
gene id: 388950:A0W33_RS00845
uniprot id: A0A1I7GJR1
names: Similarity
messages: Belongs to the universal stress protein A family.

388950:A0W33 RS18475
gene id: 388950:A0W33_RS18475
uniprot id: A0A1I7FZL5
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

388950:A0W33 RS01485
gene id: 388950:A0W33_RS01485
uniprot id: A0A1I7GRD2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the arginase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide.

388950:A0W33 RS10850
gene id: 388950:A0W33_RS10850
uniprot id: A0A1I7JH92
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

388950:A0W33 RS10730
gene id: 388950:A0W33_RS10730
uniprot id: A0A1I7JI12
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

388950:A0W33 RS01720
gene id: 388950:A0W33_RS01720
uniprot id: A0A1I7GT40
names: Similarity
messages: Belongs to the SusD family.

388950:A0W33 RS17445
gene id: 388950:A0W33_RS17445
uniprot id: A0A1I7FQ60
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

388950:A0W33 RS17240
gene id: 388950:A0W33_RS17240
uniprot id: A0A1I7FNJ4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

388950:A0W33 RS13705
gene id: 388950:A0W33_RS13705
uniprot id: A0A1I7KLI3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

388950:A0W33 RS01250
gene id: 388950:A0W33_RS01250
uniprot id: A0A1I7GNN1
names: Subcellular Location Annotation
messages: Membrane

388950:A0W33 RS10970
gene id: 388950:A0W33_RS10970
uniprot id: A0A1I7JGG6
names: Similarity
names: Subunit
messages: Belongs to the aldehyde dehydrogenase family.
messages: Homotetramer.

388950:A0W33 RS02260
gene id: 388950:A0W33_RS02260
uniprot id: A0A1I7GYF8
names: Similarity
messages: Belongs to the carotenoid/retinoid oxidoreductase family.

388950:A0W33 RS06155
gene id: 388950:A0W33_RS06155
uniprot id: A0A1I7ILW8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bTHX family.

388950:A0W33 RS10740
gene id: 388950:A0W33_RS10740
uniprot id: A0A1I7JI37
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

388950:A0W33 RS06580
gene id: 388950:A0W33_RS06580
uniprot id: A0A1I7IHU0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

388950:A0W33 RS11405
gene id: 388950:A0W33_RS11405
uniprot id: A0A1I7JDR8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

388950:A0W33 RS12835
gene id: 388950:A0W33_RS12835
uniprot id: A0A1I7J3W8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

388950:A0W33 RS11295
gene id: 388950:A0W33_RS11295
uniprot id: A0A1I7JED6
names: Subcellular Location Annotation
messages: Membrane

388950:A0W33 RS05985
gene id: 388950:A0W33_RS05985
uniprot id: A0A1I7IN97
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

388950:A0W33 RS11745
gene id: 388950:A0W33_RS11745
uniprot id: A0A1I7JBN7
names: Subcellular Location Annotation
messages: Cytoplasm

388950:A0W33 RS09375
gene id: 388950:A0W33_RS09375
uniprot id: A0A1I7HSU2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

388950:A0W33 RS10640
gene id: 388950:A0W33_RS10640
uniprot id: A0A1I7JIN2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

388950:A0W33 RS16410
gene id: 388950:A0W33_RS16410
uniprot id: A0A1I7FG67
names: Subcellular Location Annotation
messages: Membrane

388950:A0W33 RS17570
gene id: 388950:A0W33_RS17570
uniprot id: A0A1I7FRF8
names: Subcellular Location Annotation
messages: Nucleus

388950:A0W33 RS10270
gene id: 388950:A0W33_RS10270
uniprot id: A0A1I7JL11
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

388950:A0W33 RS05450
gene id: 388950:A0W33_RS05450
uniprot id: A0A1I7K8L1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

388950:A0W33 RS09790
gene id: 388950:A0W33_RS09790
uniprot id: A0A1I7JP62
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

388950:A0W33 RS07545
gene id: 388950:A0W33_RS07545
uniprot id: A0A1I7I922
names: Similarity
messages: Belongs to the PGI/PMI family.

388950:A0W33 RS06395
gene id: 388950:A0W33_RS06395
uniprot id: A0A1I7IJD1
names: Similarity
messages: Belongs to the LOG family.

388950:A0W33 RS13920
gene id: 388950:A0W33_RS13920
uniprot id: A0A1I7KKR1
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

388950:A0W33 RS05290
gene id: 388950:A0W33_RS05290
uniprot id: A0A1I7K7L2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endonuclease V family.
messages: Cytoplasm
messages: DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA.

388950:A0W33 RS05300
gene id: 388950:A0W33_RS05300
uniprot id: A0A1I7K7R5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

388950:A0W33 RS04340
gene id: 388950:A0W33_RS04340
uniprot id: A0A1I7K1N9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

388950:A0W33 RS10435
gene id: 388950:A0W33_RS10435
uniprot id: A0A1I7JJZ7
names: Subcellular Location Annotation
messages: Membrane

388950:A0W33 RS19610
gene id: 388950:A0W33_RS19610
uniprot id: A0A1I7G8V2
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

388950:A0W33 RS01920
gene id: 388950:A0W33_RS01920
uniprot id: A0A1I7GUV2
names: Similarity
messages: Belongs to the phosphohexose mutase family.

388950:A0W33 RS12850
gene id: 388950:A0W33_RS12850
uniprot id: A0A1I7J3J0
names: Function
names: Similarity
messages: Belongs to the anhydro-N-acetylmuramic acid kinase family.
messages: Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.

388950:A0W33 RS07705
gene id: 388950:A0W33_RS07705
uniprot id: A0A1I7I7Q6
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

388950:A0W33 RS02115
gene id: 388950:A0W33_RS02115
uniprot id: A0A1I7GWT1
names: Similarity
messages: Belongs to the fabD family.

388950:A0W33 RS14615
gene id: 388950:A0W33_RS14615
uniprot id: A0A1I7KE73
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

388950:A0W33 RS11920
gene id: 388950:A0W33_RS11920
uniprot id: A0A1I7JAR1
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

388950:A0W33 RS00280
gene id: 388950:A0W33_RS00280
uniprot id: A0A1I7GEF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

388950:A0W33 RS03565
gene id: 388950:A0W33_RS03565
uniprot id: A0A1I7JX23
names: Subcellular Location Annotation
messages: Membrane

388950:A0W33 RS02335
gene id: 388950:A0W33_RS02335
uniprot id: A0A1I7GZ43
names: Subcellular Location Annotation
messages: Membrane

388950:A0W33 RS00800
gene id: 388950:A0W33_RS00800
uniprot id: A0A1I7GJA4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

388950:A0W33 RS08825
gene id: 388950:A0W33_RS08825
uniprot id: A0A1I7HXX6
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

388950:A0W33 RS20500
gene id: 388950:A0W33_RS20500
uniprot id: A0A1I7KPP0
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

388950:A0W33 RS12575
gene id: 388950:A0W33_RS12575
uniprot id: A0A1I7J5Y1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

388950:A0W33 RS02155
gene id: 388950:A0W33_RS02155
uniprot id: A0A1I7GXB3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

388950:A0W33 RS06325
gene id: 388950:A0W33_RS06325
uniprot id: A0A1I7IK93
names: Similarity
messages: Belongs to the arginase family.

388950:A0W33 RS18480
gene id: 388950:A0W33_RS18480
uniprot id: A0A1I7FZR8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
messages: Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.
messages: Cytoplasm

388950:A0W33 RS02105
gene id: 388950:A0W33_RS02105
uniprot id: A0A1I7GWP5
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

388950:A0W33 RS13700
gene id: 388950:A0W33_RS13700
uniprot id: A0A1I7KLN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

388950:A0W33 RS00605
gene id: 388950:A0W33_RS00605
uniprot id: A0A1I7GHR1
names: Subcellular Location Annotation
messages: Membrane

388950:A0W33 RS11025
gene id: 388950:A0W33_RS11025
uniprot id: A0A1I7JG57
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

388950:A0W33 RS10765
gene id: 388950:A0W33_RS10765
uniprot id: A0A1I7JHY8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

388950:A0W33 RS18345
gene id: 388950:A0W33_RS18345
uniprot id: A0A1I7FYK6
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

388950:A0W33 RS03240
gene id: 388950:A0W33_RS03240
uniprot id: A0A1I7H6F6
names: Similarity
messages: Belongs to the CinA family.

388950:A0W33 RS07070
gene id: 388950:A0W33_RS07070
uniprot id: A0A1I7ID92
names: Similarity
messages: Belongs to the peptidase C56 family.

388950:A0W33 RS10835
gene id: 388950:A0W33_RS10835
uniprot id: A0A1I7JHC9
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

388950:A0W33 RS15905
gene id: 388950:A0W33_RS15905
uniprot id: A0A1I7KTA3
names: Similarity
messages: Belongs to the group II decarboxylase family.

388950:A0W33 RS19255
gene id: 388950:A0W33_RS19255
uniprot id: A0A1I7G6D7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

388950:A0W33 RS09005
gene id: 388950:A0W33_RS09005
uniprot id: A0A1I7HX15
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

388950:A0W33 RS02400
gene id: 388950:A0W33_RS02400
uniprot id: A0A1I7GZL0
names: Function
names: Similarity
messages: A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.
messages: Belongs to the NifU family.

388950:A0W33 RS06125
gene id: 388950:A0W33_RS06125
uniprot id: A0A1I7IM18
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Probably interacts with PlsX.

388950:A0W33 RS14790
gene id: 388950:A0W33_RS14790
uniprot id: A0A1I7KF83
names: Similarity
names: Subunit
messages: Belongs to the glycosyltransferase 20 family.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the trehalose phosphatase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 20 family.

388950:A0W33 RS20310
gene id: 388950:A0W33_RS20310
uniprot id: A0A1I7KNR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

388950:A0W33 RS04520
gene id: 388950:A0W33_RS04520
uniprot id: A0A1I7K2K6
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

388950:A0W33 RS17945
gene id: 388950:A0W33_RS17945
uniprot id: A0A1I7FV62
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

388950:A0W33 RS12800
gene id: 388950:A0W33_RS12800
uniprot id: A0A1I7J490
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

388950:A0W33 RS12105
gene id: 388950:A0W33_RS12105
uniprot id: A0A1I7J9G7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

388950:A0W33 RS07310
gene id: 388950:A0W33_RS07310
uniprot id: A0A1I7IBH0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

388950:A0W33 RS18900
gene id: 388950:A0W33_RS18900
uniprot id: A0A1I7G3A3
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

388950:A0W33 RS10355
gene id: 388950:A0W33_RS10355
uniprot id: A0A1I7JKF8
names: Similarity
messages: Belongs to the SusD family.

388950:A0W33 RS12475
gene id: 388950:A0W33_RS12475
uniprot id: A0A1I7J6R4
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

388950:A0W33 RS06810
gene id: 388950:A0W33_RS06810
uniprot id: A0A1I7IFF7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

388950:A0W33 RS15465
gene id: 388950:A0W33_RS15465
uniprot id: A0A1I7KIS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Membrane

388950:A0W33 RS13385
gene id: 388950:A0W33_RS13385
uniprot id: A0A1I7IZZ0
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

388950:A0W33 RS19530
gene id: 388950:A0W33_RS19530
uniprot id: A0A1I7G888
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

388950:A0W33 RS19935
gene id: 388950:A0W33_RS19935
uniprot id: A0A1I7GBG1
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

388950:A0W33 RS06025
gene id: 388950:A0W33_RS06025
uniprot id: A0A1I7IN13
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SIS family. GmhA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
messages: Cytoplasm
messages: The reaction produces a racemic mixture of D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate.

388950:A0W33 RS16745
gene id: 388950:A0W33_RS16745
uniprot id: A0A1I7FJH3
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

388950:A0W33 RS07445
gene id: 388950:A0W33_RS07445
uniprot id: A0A1I7IAE3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

388950:A0W33 RS05785
gene id: 388950:A0W33_RS05785
uniprot id: A0A1I7KA03
names: Similarity
messages: Belongs to the transglycosylase Slt family.

388950:A0W33 RS09255
gene id: 388950:A0W33_RS09255
uniprot id: A0A1I7HU11
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

388950:A0W33 RS08530
gene id: 388950:A0W33_RS08530
uniprot id: A0A1I7I0J8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

388950:A0W33 RS00865
gene id: 388950:A0W33_RS00865
uniprot id: A0A1I7GK63
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

388950:A0W33 RS11800
gene id: 388950:A0W33_RS11800
uniprot id: A0A1I7JB96
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

388950:A0W33 RS01205
gene id: 388950:A0W33_RS01205
uniprot id: A0A1I7GN73
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

388950:A0W33 RS08610
gene id: 388950:A0W33_RS08610
uniprot id: A0A1I7I021
names: Similarity
messages: Belongs to the prokaryotic GSH synthase family.

388950:A0W33 RS00745
gene id: 388950:A0W33_RS00745
uniprot id: A0A1I7GIW1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RuvC family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.

388950:A0W33 RS03295
gene id: 388950:A0W33_RS03295
uniprot id: A0A1I7H6U6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

388950:A0W33 RS14300
gene id: 388950:A0W33_RS14300
uniprot id: A0A1I7KXR1
names: Function
names: Similarity
messages: Belongs to the glycosyl hydrolase 130 family.
messages: Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man-Glc) to mannose 1-phosphate (Man1P) and glucose.

388950:A0W33 RS00835
gene id: 388950:A0W33_RS00835
uniprot id: A0A1I7GJL1
names: Similarity
messages: Belongs to the SUI1 family.

388950:A0W33 RS08205
gene id: 388950:A0W33_RS08205
uniprot id: A0A1I7I3G5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Forms a complex with TatA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.

388950:A0W33 RS15725
gene id: 388950:A0W33_RS15725
uniprot id: A0A1I7KWJ7
names: Similarity
messages: Belongs to the peptidase S33 family.

388950:A0W33 RS04360
gene id: 388950:A0W33_RS04360
uniprot id: A0A1I7K1M3
names: Subcellular Location Annotation
messages: Membrane

388950:A0W33 RS07955
gene id: 388950:A0W33_RS07955
uniprot id: A0A1I7I5U1
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

388950:A0W33 RS03950
gene id: 388950:A0W33_RS03950
uniprot id: A0A1I7JZ25
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

388950:A0W33 RS13235
gene id: 388950:A0W33_RS13235
uniprot id: A0A1I7J0W1
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

388950:A0W33 RS09340
gene id: 388950:A0W33_RS09340
uniprot id: A0A1I7HTC3
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

388950:A0W33 RS12555
gene id: 388950:A0W33_RS12555
uniprot id: A0A1I7J611
names: Caution
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
messages: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

388950:A0W33 RS14985
gene id: 388950:A0W33_RS14985
uniprot id: A0A1I7KGA7
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily.

388950:A0W33 RS16800
gene id: 388950:A0W33_RS16800
uniprot id: A0A1I7FJR0
names: Subcellular Location Annotation
messages: Membrane

388950:A0W33 RS06975
gene id: 388950:A0W33_RS06975
uniprot id: A0A1I7IE10
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

388950:A0W33 RS10260
gene id: 388950:A0W33_RS10260
uniprot id: A0A1I7JL77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

388950:A0W33 RS17025
gene id: 388950:A0W33_RS17025
uniprot id: A0A1I7FLR5
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

388950:A0W33 RS19415
gene id: 388950:A0W33_RS19415
uniprot id: A0A1I7G7G8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

388950:A0W33 RS15625
gene id: 388950:A0W33_RS15625
uniprot id: A0A1I7KW33
names: Similarity
messages: Belongs to the DSD1 family.

388950:A0W33 RS14770
gene id: 388950:A0W33_RS14770
uniprot id: A0A1I7KF75
names: Similarity
messages: Belongs to the aminoglycoside phosphotransferase family.
messages: Belongs to the glycosyl hydrolase 13 family. TreS subfamily.

388950:A0W33 RS11310
gene id: 388950:A0W33_RS11310
uniprot id: A0A1I7JE95
names: Similarity
messages: Belongs to the Nudix hydrolase family.

388950:A0W33 RS11960
gene id: 388950:A0W33_RS11960
uniprot id: A0A1I7JAA6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

388950:A0W33 RS00700
gene id: 388950:A0W33_RS00700
uniprot id: A0A1I7GID0
names: Similarity
messages: Belongs to the asparaginase 1 family.

388950:A0W33 RS14460
gene id: 388950:A0W33_RS14460
uniprot id: A0A1I7KXB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

388950:A0W33 RS07145
gene id: 388950:A0W33_RS07145
uniprot id: A0A1I7ICR6
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

388950:A0W33 RS19905
gene id: 388950:A0W33_RS19905
uniprot id: A0A1I7GB69
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

388950:A0W33 RS19955
gene id: 388950:A0W33_RS19955
uniprot id: A0A1I7GBK6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

388950:A0W33 RS18175
gene id: 388950:A0W33_RS18175
uniprot id: A0A1I7FXC6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

388950:A0W33 RS12980
gene id: 388950:A0W33_RS12980
uniprot id: A0A1I7J2N7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

388950:A0W33 RS17610
gene id: 388950:A0W33_RS17610
uniprot id: A0A1I7FRQ0
names: Subcellular Location Annotation
messages: Membrane

388950:A0W33 RS18875
gene id: 388950:A0W33_RS18875
uniprot id: A0A1I7G354
names: Subcellular Location Annotation
messages: Membrane

388950:A0W33 RS07765
gene id: 388950:A0W33_RS07765
uniprot id: A0A1I7I7D3
names: Similarity
messages: Belongs to the peptidase U62 family.

388950:A0W33 RS19900
gene id: 388950:A0W33_RS19900
uniprot id: A0A1I7GB83
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit A family.

388950:A0W33 RS07195
gene id: 388950:A0W33_RS07195
uniprot id: A0A1I7ICQ0
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

388950:A0W33 RS04305
gene id: 388950:A0W33_RS04305
uniprot id: A0A1I7K1F5
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

388950:A0W33 RS02685
gene id: 388950:A0W33_RS02685
uniprot id: A0A1I7H295
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

388950:A0W33 RS07710
gene id: 388950:A0W33_RS07710
uniprot id: A0A1I7I7Z4
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

388950:A0W33 RS11015
gene id: 388950:A0W33_RS11015
uniprot id: A0A1I7JG67
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

388950:A0W33 RS19870
gene id: 388950:A0W33_RS19870
uniprot id: A0A1I7GAW8
names: Similarity
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.

388950:A0W33 RS10070
gene id: 388950:A0W33_RS10070
uniprot id: A0A1I7JMC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmC/CycZ/HelC family.
messages: Membrane

388950:A0W33 RS18710
gene id: 388950:A0W33_RS18710
uniprot id: A0A1I7G1Q1
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

388950:A0W33 RS12755
gene id: 388950:A0W33_RS12755
uniprot id: A0A1I7J4I8
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

388950:A0W33 RS05795
gene id: 388950:A0W33_RS05795
uniprot id: A0A1I7KA16
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

388950:A0W33 RS10800
gene id: 388950:A0W33_RS10800
uniprot id: A0A1I7JHM5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

388950:A0W33 RS07680
gene id: 388950:A0W33_RS07680
uniprot id: A0A1I7I828
names: Function
names: Similarity
messages: Belongs to the peptidase S51 family.
messages: Exopeptidase that catalyzes the hydrolytic cleavage of multi-L-arginyl-poly-L-aspartic acid (cyanophycin; a water-insoluble reserve polymer) into aspartate-arginine dipeptides.

388950:A0W33 RS05805
gene id: 388950:A0W33_RS05805
uniprot id: A0A1I7KA10
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

388950:A0W33 RS10780
gene id: 388950:A0W33_RS10780
uniprot id: A0A1I7JHQ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

388950:A0W33 RS03290
gene id: 388950:A0W33_RS03290
uniprot id: A0A1I7H7E8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

388950:A0W33 RS08680
gene id: 388950:A0W33_RS08680
uniprot id: A0A1I7HZ86
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

388950:A0W33 RS16465
gene id: 388950:A0W33_RS16465
uniprot id: A0A1I7FGQ1
names: Subcellular Location Annotation
messages: Membrane

388950:A0W33 RS19775
gene id: 388950:A0W33_RS19775
uniprot id: A0A1I7GA46
names: Similarity
messages: Belongs to the ArsC family.

388950:A0W33 RS19675
gene id: 388950:A0W33_RS19675
uniprot id: A0A1I7G985
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

388950:A0W33 RS00990
gene id: 388950:A0W33_RS00990
uniprot id: A0A1I7GL42
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

388950:A0W33 RS05230
gene id: 388950:A0W33_RS05230
uniprot id: A0A1I7K7E6
names: Similarity
messages: Belongs to the CFA/CMAS family.

388950:A0W33 RS17755
gene id: 388950:A0W33_RS17755
uniprot id: A0A1I7FT66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

388950:A0W33 RS11410
gene id: 388950:A0W33_RS11410
uniprot id: A0A1I7JDR2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein L14 (rplN).

388950:A0W33 RS09745
gene id: 388950:A0W33_RS09745
uniprot id: A0A1I7JPF0
names: Similarity
messages: Belongs to the class-II fumarase/aspartase family. Aspartase subfamily.

388950:A0W33 RS09095
gene id: 388950:A0W33_RS09095
uniprot id: A0A1I7HVQ3
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

388950:A0W33 RS05590
gene id: 388950:A0W33_RS05590
uniprot id: A0A1I7K947
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

388950:A0W33 RS10820
gene id: 388950:A0W33_RS10820
uniprot id: A0A1I7JHK9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

388950:A0W33 RS08295
gene id: 388950:A0W33_RS08295
uniprot id: A0A1I7I2P1
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

388950:A0W33 RS08320
gene id: 388950:A0W33_RS08320
uniprot id: A0A1I7I327
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

388950:A0W33 RS02240
gene id: 388950:A0W33_RS02240
uniprot id: A0A1I7GY60
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

388950:A0W33 RS08975
gene id: 388950:A0W33_RS08975
uniprot id: A0A1I7HWW7
names: Similarity
messages: Belongs to the NusB family.

388950:A0W33 RS05270
gene id: 388950:A0W33_RS05270
uniprot id: A0A1I7K7I0
names: Cofactor
names: Similarity
messages: Belongs to the monomeric-type IDH family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

388950:A0W33 RS05875
gene id: 388950:A0W33_RS05875
uniprot id: A0A1I7KA97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

388950:A0W33 RS18270
gene id: 388950:A0W33_RS18270
uniprot id: A0A1I7FY62
names: Similarity
messages: Belongs to the methyltransferase superfamily.

388950:A0W33 RS02550
gene id: 388950:A0W33_RS02550
uniprot id: A0A1I7H107
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

388950:A0W33 RS14850
gene id: 388950:A0W33_RS14850
uniprot id: A0A1I7KFC9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

388950:A0W33 RS17645
gene id: 388950:A0W33_RS17645
uniprot id: A0A1I7FS45
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

388950:A0W33 RS12720
gene id: 388950:A0W33_RS12720
uniprot id: A0A1I7J4S0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

388950:A0W33 RS08355
gene id: 388950:A0W33_RS08355
uniprot id: A0A1I7I2U1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. METTL16/RlmF family.
messages: Cytoplasm
messages: Specifically methylates the adenine in position 1618 of 23S rRNA.

388950:A0W33 RS13225
gene id: 388950:A0W33_RS13225
uniprot id: A0A1I7J0Y1
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

388950:A0W33 RS04440
gene id: 388950:A0W33_RS04440
uniprot id: A0A1I7K2E4
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

388950:A0W33 RS18365
gene id: 388950:A0W33_RS18365
uniprot id: A0A1I7FZ85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

388950:A0W33 RS08190
gene id: 388950:A0W33_RS08190
uniprot id: A0A1I7I3Q8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

388950:A0W33 RS01835
gene id: 388950:A0W33_RS01835
uniprot id: A0A1I7GU01
names: Subcellular Location Annotation
messages: Membrane

388950:A0W33 RS03245
gene id: 388950:A0W33_RS03245
uniprot id: A0A1I7H6G2
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

388950:A0W33 RS17670
gene id: 388950:A0W33_RS17670
uniprot id: A0A1I7FSH0
names: Similarity
messages: Belongs to the iron-containing alcohol dehydrogenase family.

388950:A0W33 RS16215
gene id: 388950:A0W33_RS16215
uniprot id: A0A1I7FEC1
names: Similarity
messages: Belongs to the complex I 75 kDa subunit family.

388950:A0W33 RS01625
gene id: 388950:A0W33_RS01625
uniprot id: A0A1I7GSC0
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

388950:A0W33 RS08995
gene id: 388950:A0W33_RS08995
uniprot id: A0A1I7HX55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

388950:A0W33 RS00625
gene id: 388950:A0W33_RS00625
uniprot id: A0A1I7GI09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

388950:A0W33 RS09135
gene id: 388950:A0W33_RS09135
uniprot id: A0A1I7HV39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

388950:A0W33 RS09210
gene id: 388950:A0W33_RS09210
uniprot id: A0A1I7HV29
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

388950:A0W33 RS05735
gene id: 388950:A0W33_RS05735
uniprot id: A0A1I7K9R9
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

388950:A0W33 RS15855
gene id: 388950:A0W33_RS15855
uniprot id: A0A1I7KTM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

388950:A0W33 RS20535
gene id: 388950:A0W33_RS20535
uniprot id: A0A1I7KQ16
names: Subcellular Location Annotation
messages: Membrane

388950:A0W33 RS03315
gene id: 388950:A0W33_RS03315
uniprot id: A0A1I7H734
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

388950:A0W33 RS03175
gene id: 388950:A0W33_RS03175
uniprot id: A0A1I7H5Z2
names: Similarity
messages: Belongs to the AlaDH/PNT family.

388950:A0W33 RS04345
gene id: 388950:A0W33_RS04345
uniprot id: A0A1I7K1F4
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 3 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

388950:A0W33 RS05170
gene id: 388950:A0W33_RS05170
uniprot id: A0A1I7K6U8
names: Similarity
messages: Belongs to the glycosyl hydrolase 8 (cellulase D) family.

388950:A0W33 RS19450
gene id: 388950:A0W33_RS19450
uniprot id: A0A1I7G7R1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

388950:A0W33 RS10720
gene id: 388950:A0W33_RS10720
uniprot id: A0A1I7JI25
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

388950:A0W33 RS16585
gene id: 388950:A0W33_RS16585
uniprot id: A0A1I7FHU5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inositol monophosphatase superfamily. CysQ family.
messages: Cell membrane
messages: Converts adenosine-3',5'-bisphosphate (PAP) to AMP.

388950:A0W33 RS18150
gene id: 388950:A0W33_RS18150
uniprot id: A0A1I7FXB4
names: Similarity
messages: Belongs to the threonine aldolase family.

388950:A0W33 RS12965
gene id: 388950:A0W33_RS12965
uniprot id: A0A1I7J2Q8
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

388950:A0W33 RS17310
gene id: 388950:A0W33_RS17310
uniprot id: A0A1I7FP43
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

388950:A0W33 RS19410
gene id: 388950:A0W33_RS19410
uniprot id: A0A1I7G7F7
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

388950:A0W33 RS15900
gene id: 388950:A0W33_RS15900
uniprot id: A0A1I7KTE2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

388950:A0W33 RS08250
gene id: 388950:A0W33_RS08250
uniprot id: A0A1I7I324
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

388950:A0W33 RS08665
gene id: 388950:A0W33_RS08665
uniprot id: A0A1I7HZA0
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

388950:A0W33 RS19545
gene id: 388950:A0W33_RS19545
uniprot id: A0A1I7G8D1
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

388950:A0W33 RS19850
gene id: 388950:A0W33_RS19850
uniprot id: A0A1I7GAU0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

388950:A0W33 RS04300
gene id: 388950:A0W33_RS04300
uniprot id: A0A1I7K1E0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

388950:A0W33 RS06135
gene id: 388950:A0W33_RS06135
uniprot id: A0A1I7IM48
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates ribosomal protein L11.

388950:A0W33 RS15305
gene id: 388950:A0W33_RS15305
uniprot id: A0A1I7KHS1
names: Subcellular Location Annotation
messages: Membrane

388950:A0W33 RS09440
gene id: 388950:A0W33_RS09440
uniprot id: A0A1I7HSE0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

388950:A0W33 RS12840
gene id: 388950:A0W33_RS12840
uniprot id: A0A1I7J3S5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

388950:A0W33 RS02190
gene id: 388950:A0W33_RS02190
uniprot id: A0A1I7GXM7
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

388950:A0W33 RS01320
gene id: 388950:A0W33_RS01320
uniprot id: A0A1I7GPD6
names: Cofactor
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.

388950:A0W33 RS17535
gene id: 388950:A0W33_RS17535
uniprot id: A0A1I7FR27
names: Subcellular Location Annotation
messages: Membrane

388950:A0W33 RS06895
gene id: 388950:A0W33_RS06895
uniprot id: A0A1I7IEW0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

388950:A0W33 RS01850
gene id: 388950:A0W33_RS01850
uniprot id: A0A1I7GU39
names: Similarity
messages: Belongs to the SAICAR synthetase family.

388950:A0W33 RS09550
gene id: 388950:A0W33_RS09550
uniprot id: A0A1I7HS47
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

388950:A0W33 RS11250
gene id: 388950:A0W33_RS11250
uniprot id: A0A1I7JEM9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

388950:A0W33 RS02560
gene id: 388950:A0W33_RS02560
uniprot id: A0A1I7H1P6
names: Subcellular Location Annotation
messages: Membrane

388950:A0W33 RS07670
gene id: 388950:A0W33_RS07670
uniprot id: A0A1I7I839
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

388950:A0W33 RS14265
gene id: 388950:A0W33_RS14265
uniprot id: A0A1I7KUF6
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

388950:A0W33 RS04475
gene id: 388950:A0W33_RS04475
uniprot id: A0A1I7K2F1
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

388950:A0W33 RS13610
gene id: 388950:A0W33_RS13610
uniprot id: A0A1I7KLX1
names: Similarity
messages: Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.

388950:A0W33 RS02575
gene id: 388950:A0W33_RS02575
uniprot id: A0A1I7H1J0
names: Subcellular Location Annotation
messages: Membrane

388950:A0W33 RS18955
gene id: 388950:A0W33_RS18955
uniprot id: A0A1I7G446
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
messages: Homodimer.

388950:A0W33 RS04900
gene id: 388950:A0W33_RS04900
uniprot id: A0A1I7K519
names: Similarity
messages: Belongs to the UxaA family.

388950:A0W33 RS14330
gene id: 388950:A0W33_RS14330
uniprot id: A0A1I7KXL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

388950:A0W33 RS17350
gene id: 388950:A0W33_RS17350
uniprot id: A0A1I7FPW3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

388950:A0W33 RS07285
gene id: 388950:A0W33_RS07285
uniprot id: A0A1I7IC50
names: Subcellular Location Annotation
messages: Membrane

388950:A0W33 RS12600
gene id: 388950:A0W33_RS12600
uniprot id: A0A1I7J5V2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.

388950:A0W33 RS10795
gene id: 388950:A0W33_RS10795
uniprot id: A0A1I7JHN4
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

388950:A0W33 RS16720
gene id: 388950:A0W33_RS16720
uniprot id: A0A1I7FJ57
names: Similarity
messages: Belongs to the YjiK family.

388950:A0W33 RS09485
gene id: 388950:A0W33_RS09485
uniprot id: A0A1I7HRU1
names: Similarity
messages: Belongs to the GroES chaperonin family.

388950:A0W33 RS09220
gene id: 388950:A0W33_RS09220
uniprot id: A0A1I7HUZ0
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

388950:A0W33 RS19405
gene id: 388950:A0W33_RS19405
uniprot id: A0A1I7G7R6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

388950:A0W33 RS10715
gene id: 388950:A0W33_RS10715
uniprot id: A0A1I7JI55
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

388950:A0W33 RS17425
gene id: 388950:A0W33_RS17425
uniprot id: A0A1I7FQI1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
messages: Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
messages: Homodimer.

388950:A0W33 RS09285
gene id: 388950:A0W33_RS09285
uniprot id: A0A1I7HUC4
names: Function
names: Similarity
messages: Belongs to the aromatic-ring hydroxylase family. KMO subfamily.
messages: Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.

388950:A0W33 RS10395
gene id: 388950:A0W33_RS10395
uniprot id: A0A1I7JK61
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

388950:A0W33 RS08550
gene id: 388950:A0W33_RS08550
uniprot id: A0A1I7I0F3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

388950:A0W33 RS08715
gene id: 388950:A0W33_RS08715
uniprot id: A0A1I7HYS2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

388950:A0W33 RS07425
gene id: 388950:A0W33_RS07425
uniprot id: A0A1I7IAA1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.

388950:A0W33 RS11200
gene id: 388950:A0W33_RS11200
uniprot id: A0A1I7JEY5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reduced FMN (FMNH(2)).

388950:A0W33 RS11520
gene id: 388950:A0W33_RS11520
uniprot id: A0A1I7JD02
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

388950:A0W33 RS11125
gene id: 388950:A0W33_RS11125
uniprot id: A0A1I7JFF6
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

388950:A0W33 RS05255
gene id: 388950:A0W33_RS05255
uniprot id: A0A1I7K7F7
names: Similarity
messages: Belongs to the peptidase M16 family.

388950:A0W33 RS11260
gene id: 388950:A0W33_RS11260
uniprot id: A0A1I7JEL4
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
messages: Part of the 50S ribosomal subunit.

388950:A0W33 RS06820
gene id: 388950:A0W33_RS06820
uniprot id: A0A1I7IFC9
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

388950:A0W33 RS07235
gene id: 388950:A0W33_RS07235
uniprot id: A0A1I7IC43
names: Subcellular Location Annotation
messages: Membrane

388950:A0W33 RS10165
gene id: 388950:A0W33_RS10165
uniprot id: A0A1I7JLR3
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

388950:A0W33 RS01405
gene id: 388950:A0W33_RS01405
uniprot id: A0A1I7GQ83
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the YjjX NTPase family.
messages: Binds 1 divalent metal cation per subunit; can use either Mg(2+) or Mn(2+).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA/RNA precursor pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

388950:A0W33 RS19115
gene id: 388950:A0W33_RS19115
uniprot id: A0A1I7G5D4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

388950:A0W33 RS11230
gene id: 388950:A0W33_RS11230
uniprot id: A0A1I7JER5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

388950:A0W33 RS10245
gene id: 388950:A0W33_RS10245
uniprot id: A0A1I7JL70
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

388950:A0W33 RS20525
gene id: 388950:A0W33_RS20525
uniprot id: A0A1I7KPS5
names: Subcellular Location Annotation
messages: Membrane

388950:A0W33 RS08140
gene id: 388950:A0W33_RS08140
uniprot id: A0A1I7I420
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

388950:A0W33 RS04145
gene id: 388950:A0W33_RS04145
uniprot id: A0A1I7K066
names: Similarity
messages: Belongs to the ClpA/ClpB family.

388950:A0W33 RS02910
gene id: 388950:A0W33_RS02910
uniprot id: A0A1I7H450
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

388950:A0W33 RS13570
gene id: 388950:A0W33_RS13570
uniprot id: A0A1I7KM12
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MenA family. Type 1 subfamily.
messages: Cell membrane
messages: Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).
messages: Membrane

388950:A0W33 RS08400
gene id: 388950:A0W33_RS08400
uniprot id: A0A1I7I1W1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Membrane

388950:A0W33 RS10380
gene id: 388950:A0W33_RS10380
uniprot id: A0A1I7JKC6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

388950:A0W33 RS03825
gene id: 388950:A0W33_RS03825
uniprot id: A0A1I7JYH9
names: Similarity
messages: Belongs to the peptidase S9A family.

388950:A0W33 RS14830
gene id: 388950:A0W33_RS14830
uniprot id: A0A1I7KF94
names: Similarity
messages: Belongs to the aspartokinase family.

388950:A0W33 RS12075
gene id: 388950:A0W33_RS12075
uniprot id: A0A1I7J9V3
names: Subcellular Location Annotation
messages: Membrane

388950:A0W33 RS01545
gene id: 388950:A0W33_RS01545
uniprot id: A0A1I7GRK6
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

388950:A0W33 RS15545
gene id: 388950:A0W33_RS15545
uniprot id: A0A1I7KVQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the etk/wzc family.
messages: Cell inner membrane
messages: Membrane

388950:A0W33 RS10365
gene id: 388950:A0W33_RS10365
uniprot id: A0A1I7JKI9
names: Similarity
messages: Belongs to the peptidase S9C family.

388950:A0W33 RS09985
gene id: 388950:A0W33_RS09985
uniprot id: A0A1I7JMW8
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

388950:A0W33 RS06865
gene id: 388950:A0W33_RS06865
uniprot id: A0A1I7IEX9
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. S-2-haloalkanoic acid dehalogenase family.

388950:A0W33 RS18340
gene id: 388950:A0W33_RS18340
uniprot id: A0A1I7FYP1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

388950:A0W33 RS01915
gene id: 388950:A0W33_RS01915
uniprot id: A0A1I7GUQ2
names: Cofactor
names: Similarity
messages: Belongs to the 4HPPD family.
messages: Binds 1 Fe cation per subunit.

388950:A0W33 RS11570
gene id: 388950:A0W33_RS11570
uniprot id: A0A1I7JCT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

388950:A0W33 RS18545
gene id: 388950:A0W33_RS18545
uniprot id: A0A1I7G0A6
names: Similarity
messages: Belongs to the DEAD box helicase family.

388950:A0W33 RS13560
gene id: 388950:A0W33_RS13560
uniprot id: A0A1I7KMA5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

388950:A0W33 RS15435
gene id: 388950:A0W33_RS15435
uniprot id: A0A1I7KIN8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

388950:A0W33 RS14375
gene id: 388950:A0W33_RS14375
uniprot id: A0A1I7KX68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VKOR family.
messages: Membrane

388950:A0W33 RS01560
gene id: 388950:A0W33_RS01560
uniprot id: A0A1I7GRP1
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

388950:A0W33 RS07455
gene id: 388950:A0W33_RS07455
uniprot id: A0A1I7IAA6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

388950:A0W33 RS10095
gene id: 388950:A0W33_RS10095
uniprot id: A0A1I7JMA0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

388950:A0W33 RS04255
gene id: 388950:A0W33_RS04255
uniprot id: A0A1I7K106
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

388950:A0W33 RS11355
gene id: 388950:A0W33_RS11355
uniprot id: A0A1I7JE31
names: Subcellular Location Annotation
messages: Cytoplasm

388950:A0W33 RS18285
gene id: 388950:A0W33_RS18285
uniprot id: A0A1I7FY85
names: Subcellular Location Annotation
messages: Membrane

388950:A0W33 RS16670
gene id: 388950:A0W33_RS16670
uniprot id: A0A1I7FJ14
names: Similarity
messages: Belongs to the pyruvate kinase family.

388950:A0W33 RS11575
gene id: 388950:A0W33_RS11575
uniprot id: A0A1I7JCM8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the arabinose isomerase family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of L-arabinose to L-ribulose.

388950:A0W33 RS10665
gene id: 388950:A0W33_RS10665
uniprot id: A0A1I7JIH9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

388950:A0W33 RS05780
gene id: 388950:A0W33_RS05780
uniprot id: A0A1I7K9W6
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

388950:A0W33 RS06495
gene id: 388950:A0W33_RS06495
uniprot id: A0A1I7IIL2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

388950:A0W33 RS09065
gene id: 388950:A0W33_RS09065
uniprot id: A0A1I7HWJ1
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

388950:A0W33 RS17345
gene id: 388950:A0W33_RS17345
uniprot id: A0A1I7FPD7
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

388950:A0W33 RS13230
gene id: 388950:A0W33_RS13230
uniprot id: A0A1I7J101
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

388950:A0W33 RS04965
gene id: 388950:A0W33_RS04965
uniprot id: A0A1I7K5F7
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

388950:A0W33 RS06470
gene id: 388950:A0W33_RS06470
uniprot id: A0A1I7IIS7
names: Similarity
messages: Belongs to the Skp family.

388950:A0W33 RS14800
gene id: 388950:A0W33_RS14800
uniprot id: A0A1I7KFH0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

388950:A0W33 RS03810
gene id: 388950:A0W33_RS03810
uniprot id: A0A1I7JYI6
names: Similarity
messages: Belongs to the SusD family.

388950:A0W33 RS14640
gene id: 388950:A0W33_RS14640
uniprot id: A0A1I7KEH7
names: Similarity
messages: Belongs to the Nudix hydrolase family.

388950:A0W33 RS12650
gene id: 388950:A0W33_RS12650
uniprot id: A0A1I7J5C5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

388950:A0W33 RS10690
gene id: 388950:A0W33_RS10690
uniprot id: A0A1I7JI87
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

388950:A0W33 RS05135
gene id: 388950:A0W33_RS05135
uniprot id: A0A1I7K6R7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

388950:A0W33 RS02535
gene id: 388950:A0W33_RS02535
uniprot id: A0A1I7H0X1
names: Similarity
messages: Belongs to the thioredoxin family.

388950:A0W33 RS17370
gene id: 388950:A0W33_RS17370
uniprot id: A0A1I7FPP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

388950:A0W33 RS16900
gene id: 388950:A0W33_RS16900
uniprot id: A0A1I7FKS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

388950:A0W33 RS19710
gene id: 388950:A0W33_RS19710
uniprot id: A0A1I7G9W5
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

388950:A0W33 RS20015
gene id: 388950:A0W33_RS20015
uniprot id: A0A1I7KQ96
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

388950:A0W33 RS06440
gene id: 388950:A0W33_RS06440
uniprot id: A0A1I7IJ12
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane
messages: Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins.

388950:A0W33 RS15575
gene id: 388950:A0W33_RS15575
uniprot id: A0A1I7KVV8
names: Subcellular Location Annotation
messages: Membrane

388950:A0W33 RS15270
gene id: 388950:A0W33_RS15270
uniprot id: A0A1I7KHJ6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

388950:A0W33 RS08560
gene id: 388950:A0W33_RS08560
uniprot id: A0A1I7I094
names: Subcellular Location Annotation
messages: Membrane

388950:A0W33 RS11530
gene id: 388950:A0W33_RS11530
uniprot id: A0A1I7JCY5
names: Similarity
messages: Belongs to the aldose epimerase family.

388950:A0W33 RS06375
gene id: 388950:A0W33_RS06375
uniprot id: A0A1I7IJJ7
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

388950:A0W33 RS19300
gene id: 388950:A0W33_RS19300
uniprot id: A0A1I7G6K0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

388950:A0W33 RS14025
gene id: 388950:A0W33_RS14025
uniprot id: A0A1I7KVD4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

388950:A0W33 RS08810
gene id: 388950:A0W33_RS08810
uniprot id: A0A1I7HY08
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

388950:A0W33 RS09995
gene id: 388950:A0W33_RS09995
uniprot id: A0A1I7JMV0
names: Similarity
messages: Belongs to the AHA1 family.

388950:A0W33 RS10475
gene id: 388950:A0W33_RS10475
uniprot id: A0A1I7JJK3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

388950:A0W33 RS09325
gene id: 388950:A0W33_RS09325
uniprot id: A0A1I7HT66
names: Similarity
messages: Belongs to the sigma-54 factor family.

388950:A0W33 RS05445
gene id: 388950:A0W33_RS05445
uniprot id: A0A1I7K8F8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

388950:A0W33 RS04960
gene id: 388950:A0W33_RS04960
uniprot id: A0A1I7K5F3
names: Similarity
messages: Belongs to the glycosyl hydrolase 28 family.

388950:A0W33 RS13790
gene id: 388950:A0W33_RS13790
uniprot id: A0A1I7KLA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Membrane

388950:A0W33 RS12465
gene id: 388950:A0W33_RS12465
uniprot id: A0A1I7J6J7
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

388950:A0W33 RS02350
gene id: 388950:A0W33_RS02350
uniprot id: A0A1I7GZ48
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

388950:A0W33 RS09815
gene id: 388950:A0W33_RS09815
uniprot id: A0A1I7JP17
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

388950:A0W33 RS08165
gene id: 388950:A0W33_RS08165
uniprot id: A0A1I7I4C8
names: Similarity
messages: Belongs to the carotenoid/retinoid oxidoreductase family.

388950:A0W33 RS02760
gene id: 388950:A0W33_RS02760
uniprot id: A0A1I7H2V9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

388950:A0W33 RS10335
gene id: 388950:A0W33_RS10335
uniprot id: A0A1I7JKK5
names: Similarity
messages: Belongs to the peptidase M1 family.

388950:A0W33 RS10825
gene id: 388950:A0W33_RS10825
uniprot id: A0A1I7JHG2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

388950:A0W33 RS19700
gene id: 388950:A0W33_RS19700
uniprot id: A0A1I7G9I4
names: Similarity
messages: Belongs to the peptidase T1B family. HslV subfamily.

388950:A0W33 RS14795
gene id: 388950:A0W33_RS14795
uniprot id: A0A1I7KF89
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

388950:A0W33 RS05730
gene id: 388950:A0W33_RS05730
uniprot id: A0A1I7K9T0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

388950:A0W33 RS00285
gene id: 388950:A0W33_RS00285
uniprot id: A0A1I7GF42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

388950:A0W33 RS08785
gene id: 388950:A0W33_RS08785
uniprot id: A0A1I7HYY5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

388950:A0W33 RS03260
gene id: 388950:A0W33_RS03260
uniprot id: A0A1I7H6J0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

388950:A0W33 RS20480
gene id: 388950:A0W33_RS20480
uniprot id: A0A1I7KPM6
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

388950:A0W33 RS20145
gene id: 388950:A0W33_RS20145
uniprot id: A0A1I7KQS5
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

388950:A0W33 RS12615
gene id: 388950:A0W33_RS12615
uniprot id: A0A1I7J5N4
names: Subcellular Location Annotation
messages: Membrane

388950:A0W33 RS08085
gene id: 388950:A0W33_RS08085
uniprot id: A0A1I7I4H9
names: Subcellular Location Annotation
messages: Membrane

388950:A0W33 RS04685
gene id: 388950:A0W33_RS04685
uniprot id: A0A1I7K3M2
names: Similarity
messages: Belongs to the Dps family.

388950:A0W33 RS14930
gene id: 388950:A0W33_RS14930
uniprot id: A0A1I7KFY0
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

388950:A0W33 RS19605
gene id: 388950:A0W33_RS19605
uniprot id: A0A1I7G997
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

388950:A0W33 RS10575
gene id: 388950:A0W33_RS10575
uniprot id: A0A1I7JIV7
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

388950:A0W33 RS14580
gene id: 388950:A0W33_RS14580
uniprot id: A0A1I7KE65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Membrane

388950:A0W33 RS13390
gene id: 388950:A0W33_RS13390
uniprot id: A0A1I7IZT1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

388950:A0W33 RS19475
gene id: 388950:A0W33_RS19475
uniprot id: A0A1I7G7V9
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

388950:A0W33 RS02710
gene id: 388950:A0W33_RS02710
uniprot id: A0A1I7H2I7
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

388950:A0W33 RS01440
gene id: 388950:A0W33_RS01440
uniprot id: A0A1I7GQN2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TPP enzyme family. MenD subfamily.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
messages: Homodimer.

388950:A0W33 RS10960
gene id: 388950:A0W33_RS10960
uniprot id: A0A1I7JGG3
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

388950:A0W33 RS04385
gene id: 388950:A0W33_RS04385
uniprot id: A0A1I7K1W4
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

388950:A0W33 RS14175
gene id: 388950:A0W33_RS14175
uniprot id: A0A1I7KUX6
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

388950:A0W33 RS01530
gene id: 388950:A0W33_RS01530
uniprot id: A0A1I7GRK5
names: Subcellular Location Annotation
messages: Endoplasmic reticulum
messages: Golgi apparatus
messages: Lysosome
messages: Secreted

388950:A0W33 RS06430
gene id: 388950:A0W33_RS06430
uniprot id: A0A1I7IJ72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

388950:A0W33 RS03850
gene id: 388950:A0W33_RS03850
uniprot id: A0A1I7JYE0
names: Similarity
messages: Belongs to the peptidase M13 family.

388950:A0W33 RS16790
gene id: 388950:A0W33_RS16790
uniprot id: A0A1I7FJR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Membrane

388950:A0W33 RS12735
gene id: 388950:A0W33_RS12735
uniprot id: A0A1I7J4M9
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

388950:A0W33 RS11890
gene id: 388950:A0W33_RS11890
uniprot id: A0A1I7JB00
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

388950:A0W33 RS07200
gene id: 388950:A0W33_RS07200
uniprot id: A0A1I7ICJ4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

388950:A0W33 RS08520
gene id: 388950:A0W33_RS08520
uniprot id: A0A1I7I0P2
names: Subcellular Location Annotation
messages: Membrane

388950:A0W33 RS09555
gene id: 388950:A0W33_RS09555
uniprot id: A0A1I7HR97
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

388950:A0W33 RS20540
gene id: 388950:A0W33_RS20540
uniprot id: A0A1I7KPY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0394 family.
messages: Membrane

388950:A0W33 RS01740
gene id: 388950:A0W33_RS01740
uniprot id: A0A1I7GTU8
names: Similarity
messages: Belongs to the glycosyl hydrolase 16 family.

388950:A0W33 RS12035
gene id: 388950:A0W33_RS12035
uniprot id: A0A1I7JA37
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

388950:A0W33 RS14745
gene id: 388950:A0W33_RS14745
uniprot id: A0A1I7KF27
names: Similarity
messages: Belongs to the disproportionating enzyme family.

388950:A0W33 RS13880
gene id: 388950:A0W33_RS13880
uniprot id: A0A1I7KL16
names: Function
names: Similarity
messages: Belongs to the HscB family.
messages: Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA.

388950:A0W33 RS18440
gene id: 388950:A0W33_RS18440
uniprot id: A0A1I7FZI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

388950:A0W33 RS11955
gene id: 388950:A0W33_RS11955
uniprot id: A0A1I7JAB3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

388950:A0W33 RS04790
gene id: 388950:A0W33_RS04790
uniprot id: A0A1I7K4I7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

388950:A0W33 RS02480
gene id: 388950:A0W33_RS02480
uniprot id: A0A1I7H0A9
names: Subcellular Location Annotation
messages: Membrane

388950:A0W33 RS09380
gene id: 388950:A0W33_RS09380
uniprot id: A0A1I7HT91
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

388950:A0W33 RS06785
gene id: 388950:A0W33_RS06785
uniprot id: A0A1I7IFP6
names: Similarity
messages: Belongs to the calycin superfamily. Lipocalin family.

388950:A0W33 RS12370
gene id: 388950:A0W33_RS12370
uniprot id: A0A1I7J7D6
names: Similarity
messages: Belongs to the IMPACT family.

388950:A0W33 RS12455
gene id: 388950:A0W33_RS12455
uniprot id: A0A1I7J6V8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

388950:A0W33 RS05710
gene id: 388950:A0W33_RS05710
uniprot id: A0A1I7K9S6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

388950:A0W33 RS19080
gene id: 388950:A0W33_RS19080
uniprot id: A0A1I7G5G2
names: Similarity
messages: Belongs to the DNA2/NAM7 helicase family.

388950:A0W33 RS13010
gene id: 388950:A0W33_RS13010
uniprot id: A0A1I7J2G5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

388950:A0W33 RS16245
gene id: 388950:A0W33_RS16245
uniprot id: A0A1I7FET7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

388950:A0W33 RS12100
gene id: 388950:A0W33_RS12100
uniprot id: A0A1I7J9H7
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

388950:A0W33 RS14815
gene id: 388950:A0W33_RS14815
uniprot id: A0A1I7KFJ7
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

388950:A0W33 RS04045
gene id: 388950:A0W33_RS04045
uniprot id: A0A1I7JZJ2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

388950:A0W33 RS01080
gene id: 388950:A0W33_RS01080
uniprot id: A0A1I7GLZ7
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

388950:A0W33 RS18010
gene id: 388950:A0W33_RS18010
uniprot id: A0A1I7FVX0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DtxR/MntR family.
messages: Cytoplasm
messages: Homodimer.

388950:A0W33 RS20600
gene id: 388950:A0W33_RS20600
uniprot id: A0A1I7KQ72
names: Similarity
messages: Belongs to the universal stress protein A family.

388950:A0W33 RS07345
gene id: 388950:A0W33_RS07345
uniprot id: A0A1I7IB92
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

388950:A0W33 RS02570
gene id: 388950:A0W33_RS02570
uniprot id: A0A1I7H1S4
names: Subcellular Location Annotation
messages: Membrane

388950:A0W33 RS12855
gene id: 388950:A0W33_RS12855
uniprot id: A0A1I7J3Q3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

388950:A0W33 RS14335
gene id: 388950:A0W33_RS14335
uniprot id: A0A1I7KXH0
names: Similarity
messages: Belongs to the SusD family.

388950:A0W33 RS14320
gene id: 388950:A0W33_RS14320
uniprot id: A0A1I7KXM8
names: Similarity
messages: Belongs to the glycosyl hydrolase 27 family.

388950:A0W33 RS12750
gene id: 388950:A0W33_RS12750
uniprot id: A0A1I7J4M5
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

388950:A0W33 RS08130
gene id: 388950:A0W33_RS08130
uniprot id: A0A1I7I485
names: Similarity
messages: Belongs to the UPF0047 family.

388950:A0W33 RS17120
gene id: 388950:A0W33_RS17120
uniprot id: A0A1I7FMN2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 3B subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

388950:A0W33 RS07970
gene id: 388950:A0W33_RS07970
uniprot id: A0A1I7I683
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

388950:A0W33 RS17110
gene id: 388950:A0W33_RS17110
uniprot id: A0A1I7FMG0
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

388950:A0W33 RS14625
gene id: 388950:A0W33_RS14625
uniprot id: A0A1I7KE25
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

388950:A0W33 RS13505
gene id: 388950:A0W33_RS13505
uniprot id: A0A1I7KMD5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

388950:A0W33 RS07980
gene id: 388950:A0W33_RS07980
uniprot id: A0A1I7I644
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

388950:A0W33 RS11280
gene id: 388950:A0W33_RS11280
uniprot id: A0A1I7JEF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

388950:A0W33 RS13295
gene id: 388950:A0W33_RS13295
uniprot id: A0A1I7J0F7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

388950:A0W33 RS17515
gene id: 388950:A0W33_RS17515
uniprot id: A0A1I7FQS5
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

388950:A0W33 RS18015
gene id: 388950:A0W33_RS18015
uniprot id: A0A1I7FW21
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

388950:A0W33 RS17845
gene id: 388950:A0W33_RS17845
uniprot id: A0A1I7FU74
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

388950:A0W33 RS10675
gene id: 388950:A0W33_RS10675
uniprot id: A0A1I7JIG0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

388950:A0W33 RS11830
gene id: 388950:A0W33_RS11830
uniprot id: A0A1I7JB81
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

388950:A0W33 RS19235
gene id: 388950:A0W33_RS19235
uniprot id: A0A1I7G6A2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

388950:A0W33 RS13360
gene id: 388950:A0W33_RS13360
uniprot id: A0A1I7J039
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

388950:A0W33 RS19315
gene id: 388950:A0W33_RS19315
uniprot id: A0A1I7G6P1
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. Fucose synthase subfamily.
messages: Catalyzes the two-step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.

388950:A0W33 RS03155
gene id: 388950:A0W33_RS03155
uniprot id: A0A1I7H617
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

388950:A0W33 RS07380
gene id: 388950:A0W33_RS07380
uniprot id: A0A1I7IB80
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

388950:A0W33 RS19770
gene id: 388950:A0W33_RS19770
uniprot id: A0A1I7GA00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

388950:A0W33 RS15680
gene id: 388950:A0W33_RS15680
uniprot id: A0A1I7KWQ3
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

388950:A0W33 RS11660
gene id: 388950:A0W33_RS11660
uniprot id: A0A1I7JC86
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

388950:A0W33 RS00020
gene id: 388950:A0W33_RS00020
uniprot id: A0A1I7GC65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAL/histidase family.
messages: Cytoplasm

388950:A0W33 RS18005
gene id: 388950:A0W33_RS18005
uniprot id: A0A1I7FVR5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NRAMP family.
messages: Cell membrane
messages: H(+)-stimulated, divalent metal cation uptake system.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

388950:A0W33 RS02005
gene id: 388950:A0W33_RS02005
uniprot id: A0A1I7GVM8
names: Similarity
messages: Belongs to the OsmC/Ohr family.

388950:A0W33 RS05845
gene id: 388950:A0W33_RS05845
uniprot id: A0A1I7KAA3
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

388950:A0W33 RS04770
gene id: 388950:A0W33_RS04770
uniprot id: A0A1I7K485
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.

388950:A0W33 RS08405
gene id: 388950:A0W33_RS08405
uniprot id: A0A1I7I1U5
names: Similarity
messages: Belongs to the DinB family.

388950:A0W33 RS02885
gene id: 388950:A0W33_RS02885
uniprot id: A0A1I7H3S6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

388950:A0W33 RS08330
gene id: 388950:A0W33_RS08330
uniprot id: A0A1I7I2G5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

388950:A0W33 RS18805
gene id: 388950:A0W33_RS18805
uniprot id: A0A1I7G2H1
names: Subcellular Location Annotation
messages: Membrane

388950:A0W33 RS13250
gene id: 388950:A0W33_RS13250
uniprot id: A0A1I7J0R8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

388950:A0W33 RS16195
gene id: 388950:A0W33_RS16195
uniprot id: A0A1I7FE19
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

388950:A0W33 RS02600
gene id: 388950:A0W33_RS02600
uniprot id: A0A1I7H1I2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

388950:A0W33 RS02985
gene id: 388950:A0W33_RS02985
uniprot id: A0A1I7H4N5
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

388950:A0W33 RS04035
gene id: 388950:A0W33_RS04035
uniprot id: A0A1I7JZM8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the xylose isomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.

388950:A0W33 RS15025
gene id: 388950:A0W33_RS15025
uniprot id: A0A1I7KGC7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the trans-sulfuration enzymes family. MetZ subfamily.
messages: Catalyzes the formation of L-homocysteine from O-succinyl-L-homoserine (OSHS) and hydrogen sulfide.
messages: Homotetramer.

388950:A0W33 RS00680
gene id: 388950:A0W33_RS00680
uniprot id: A0A1I7GIF4
names: Similarity
messages: Belongs to the ABC transporter superfamily.

388950:A0W33 RS12515
gene id: 388950:A0W33_RS12515
uniprot id: A0A1I7J6G7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

388950:A0W33 RS01875
gene id: 388950:A0W33_RS01875
uniprot id: A0A1I7GUG9
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

388950:A0W33 RS00975
gene id: 388950:A0W33_RS00975
uniprot id: A0A1I7GKZ6
names: Subcellular Location Annotation
messages: Membrane

388950:A0W33 RS05470
gene id: 388950:A0W33_RS05470
uniprot id: A0A1I7K8T5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

388950:A0W33 RS05020
gene id: 388950:A0W33_RS05020
uniprot id: A0A1I7K5R1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the KduI family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of 5-dehydro-4-deoxy-D-glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate.

388950:A0W33 RS19035
gene id: 388950:A0W33_RS19035
uniprot id: A0A1I7G4H7
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

388950:A0W33 RS08655
gene id: 388950:A0W33_RS08655
uniprot id: A0A1I7I002
names: Subcellular Location Annotation
messages: Secreted

388950:A0W33 RS15170
gene id: 388950:A0W33_RS15170
uniprot id: A0A1I7KH14
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

388950:A0W33 RS16985
gene id: 388950:A0W33_RS16985
uniprot id: A0A1I7FLE1
names: Similarity
messages: Belongs to the manganese catalase family.

388950:A0W33 RS09705
gene id: 388950:A0W33_RS09705
uniprot id: A0A1I7HQ60
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

388950:A0W33 RS15980
gene id: 388950:A0W33_RS15980
uniprot id: A0A1I7KSZ2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

388950:A0W33 RS07660
gene id: 388950:A0W33_RS07660
uniprot id: A0A1I7I849
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.

388950:A0W33 RS15805
gene id: 388950:A0W33_RS15805
uniprot id: A0A1I7KTL5
names: Similarity
messages: Belongs to the UDP-galactopyranose/dTDP-fucopyranose mutase family.

388950:A0W33 RS14845
gene id: 388950:A0W33_RS14845
uniprot id: A0A1I7KFL6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.

388950:A0W33 RS18100
gene id: 388950:A0W33_RS18100
uniprot id: A0A1I7FWT2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 51 family.
messages: Cell membrane
messages: Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors.

388950:A0W33 RS11470
gene id: 388950:A0W33_RS11470
uniprot id: A0A1I7JDB7
names: Similarity
messages: Belongs to the glycosyl hydrolase 51 family.

388950:A0W33 RS05945
gene id: 388950:A0W33_RS05945
uniprot id: A0A1I7INQ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

388950:A0W33 RS09835
gene id: 388950:A0W33_RS09835
uniprot id: A0A1I7JP08
names: Subcellular Location Annotation
messages: Membrane

388950:A0W33 RS11285
gene id: 388950:A0W33_RS11285
uniprot id: A0A1I7JEE9
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

388950:A0W33 RS16180
gene id: 388950:A0W33_RS16180
uniprot id: A0A1I7FDU8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

388950:A0W33 RS02750
gene id: 388950:A0W33_RS02750
uniprot id: A0A1I7H2R5
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

388950:A0W33 RS10100
gene id: 388950:A0W33_RS10100
uniprot id: A0A1I7JM55
names: Function
names: Similarity
messages: Belongs to the PstS family.
messages: Involved in the system for phosphate transport across the cytoplasmic membrane.

388950:A0W33 RS07315
gene id: 388950:A0W33_RS07315
uniprot id: A0A1I7IBE5
names: Similarity
messages: Belongs to the glutathione peroxidase family.

388950:A0W33 RS12270
gene id: 388950:A0W33_RS12270
uniprot id: A0A1I7J8F2
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

388950:A0W33 RS13355
gene id: 388950:A0W33_RS13355
uniprot id: A0A1I7J070
names: Caution
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

388950:A0W33 RS12390
gene id: 388950:A0W33_RS12390
uniprot id: A0A1I7J7D5
names: Cofactor
names: Similarity
messages: Belongs to the fatty acid desaturase type 2 family.
messages: Binds 2 iron ions per subunit.

388950:A0W33 RS17715
gene id: 388950:A0W33_RS17715
uniprot id: A0A1I7FSZ8
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

388950:A0W33 RS18500
gene id: 388950:A0W33_RS18500
uniprot id: A0A1I7G099
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

388950:A0W33 RS17235
gene id: 388950:A0W33_RS17235
uniprot id: A0A1I7FNI3
names: Similarity
messages: Belongs to the threonine synthase family.

388950:A0W33 RS12320
gene id: 388950:A0W33_RS12320
uniprot id: A0A1I7J7W8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

388950:A0W33 RS02140
gene id: 388950:A0W33_RS02140
uniprot id: A0A1I7GX63
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

388950:A0W33 RS15740
gene id: 388950:A0W33_RS15740
uniprot id: A0A1I7KWL7
names: Function
names: Similarity
messages: Belongs to the peptidase S51 family.
messages: Exopeptidase that catalyzes the hydrolytic cleavage of multi-L-arginyl-poly-L-aspartic acid (cyanophycin; a water-insoluble reserve polymer) into aspartate-arginine dipeptides.