373903:HORE RS04295
gene id: 373903:HORE_RS04295
uniprot id: B8CWA5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M3B family.
messages: Binds 1 zinc ion.
messages: Has oligopeptidase activity and degrades a variety of small bioactive peptides.

373903:HORE RS10085
gene id: 373903:HORE_RS10085
uniprot id: B8CZH6
names: Subcellular Location Annotation
messages: Membrane

373903:HORE RS06375
gene id: 373903:HORE_RS06375
uniprot id: B8CXF1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

373903:HORE RS06420
gene id: 373903:HORE_RS06420
uniprot id: B8CXG0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

373903:HORE RS09165
gene id: 373903:HORE_RS09165
uniprot id: B8CYZ2
names: Similarity
messages: Belongs to the peptidase S8 family.

373903:HORE RS04215
gene id: 373903:HORE_RS04215
uniprot id: B8CW89
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

373903:HORE RS04060
gene id: 373903:HORE_RS04060
uniprot id: B8CW58
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

373903:HORE RS03005
gene id: 373903:HORE_RS03005
uniprot id: B8D293
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

373903:HORE RS10640
gene id: 373903:HORE_RS10640
uniprot id: B8CZV1
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

373903:HORE RS11065
gene id: 373903:HORE_RS11065
uniprot id: B8D0E5
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

373903:HORE RS10125
gene id: 373903:HORE_RS10125
uniprot id: B8CZI4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

373903:HORE RS07285
gene id: 373903:HORE_RS07285
uniprot id: B8CXX7
names: Similarity
messages: Belongs to the Nudix hydrolase family.

373903:HORE RS02875
gene id: 373903:HORE_RS02875
uniprot id: B8D274
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Monomer.

373903:HORE RS03680
gene id: 373903:HORE_RS03680
uniprot id: B8CVY1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

373903:HORE RS04600
gene id: 373903:HORE_RS04600
uniprot id: B8CWG6
names: Subcellular Location Annotation
messages: Membrane

373903:HORE RS00435
gene id: 373903:HORE_RS00435
uniprot id: B8D077
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Cytoplasm

373903:HORE RS00595
gene id: 373903:HORE_RS00595
uniprot id: B8D0A5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidylate synthase ThyX family.
messages: Binds 4 FAD per tetramer. Each FAD binding site is formed by three monomers.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
messages: Homotetramer.

373903:HORE RS06295
gene id: 373903:HORE_RS06295
uniprot id: B8CXD5
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

373903:HORE RS04985
gene id: 373903:HORE_RS04985
uniprot id: B8CWN5
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

373903:HORE RS00285
gene id: 373903:HORE_RS00285
uniprot id: B8D047
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

373903:HORE RS05185
gene id: 373903:HORE_RS05185
uniprot id: B8CWS3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

373903:HORE RS05345
gene id: 373903:HORE_RS05345
uniprot id: B8CWV4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

373903:HORE RS02185
gene id: 373903:HORE_RS02185
uniprot id: B8D1U0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

373903:HORE RS10785
gene id: 373903:HORE_RS10785
uniprot id: B8CZX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

373903:HORE RS01660
gene id: 373903:HORE_RS01660
uniprot id: B8D1J3
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

373903:HORE RS12135
gene id: 373903:HORE_RS12135
uniprot id: B8D1D6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

373903:HORE RS06345
gene id: 373903:HORE_RS06345
uniprot id: B8CXE5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.

373903:HORE RS09775
gene id: 373903:HORE_RS09775
uniprot id: B8CZB5
names: Subcellular Location Annotation
messages: Membrane

373903:HORE RS02910
gene id: 373903:HORE_RS02910
uniprot id: B8D281
names: Subcellular Location Annotation
messages: Cell membrane

373903:HORE RS04320
gene id: 373903:HORE_RS04320
uniprot id: B8CWB0
names: Similarity
messages: Belongs to the TPP enzyme family.

373903:HORE RS09270
gene id: 373903:HORE_RS09270
uniprot id: B8CZ13
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase delta chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

373903:HORE RS02235
gene id: 373903:HORE_RS02235
uniprot id: B8D1V0
names: Similarity
messages: Belongs to the glycosyl hydrolase 30 family.

373903:HORE RS03675
gene id: 373903:HORE_RS03675
uniprot id: B8CVY0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.

373903:HORE RS02660
gene id: 373903:HORE_RS02660
uniprot id: B8D234
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

373903:HORE RS05660
gene id: 373903:HORE_RS05660
uniprot id: B8CX16
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

373903:HORE RS00635
gene id: 373903:HORE_RS00635
uniprot id: B8D0B3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

373903:HORE RS09380
gene id: 373903:HORE_RS09380
uniprot id: B8CZ36
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

373903:HORE RS01420
gene id: 373903:HORE_RS01420
uniprot id: B8D152
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MntP (TC 9.B.29) family.
messages: Cell inner membrane
messages: Probably functions as a manganese efflux pump.

373903:HORE RS11655
gene id: 373903:HORE_RS11655
uniprot id: B8D0Q9
names: Similarity
messages: In the N-terminal section; belongs to the zinc metallo-hydrolase group 3 family.

373903:HORE RS03030
gene id: 373903:HORE_RS03030
uniprot id: B8D298
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
messages: Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
messages: Homodimer.

373903:HORE RS09760
gene id: 373903:HORE_RS09760
uniprot id: B8CZB2
names: Subcellular Location Annotation
messages: Membrane

373903:HORE RS11955
gene id: 373903:HORE_RS11955
uniprot id: B8D1A0
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

373903:HORE RS06220
gene id: 373903:HORE_RS06220
uniprot id: B8CXC3
names: Similarity
messages: Belongs to the CinA family.

373903:HORE RS07470
gene id: 373903:HORE_RS07470
uniprot id: B8CY14
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

373903:HORE RS10115
gene id: 373903:HORE_RS10115
uniprot id: B8CZI2
names: Function
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.
messages: Transcriptional repressor of xylose-utilizing enzymes.

373903:HORE RS11755
gene id: 373903:HORE_RS11755
uniprot id: B8D162
names: Subcellular Location Annotation
messages: Membrane

373903:HORE RS10965
gene id: 373903:HORE_RS10965
uniprot id: B8D009
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

373903:HORE RS04910
gene id: 373903:HORE_RS04910
uniprot id: B8CWM0
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

373903:HORE RS09190
gene id: 373903:HORE_RS09190
uniprot id: B8CYZ7
names: Similarity
messages: Belongs to the Skp family.

373903:HORE RS11285
gene id: 373903:HORE_RS11285
uniprot id: B8D0I8
names: Similarity
messages: Belongs to the ComB family.

373903:HORE RS10875
gene id: 373903:HORE_RS10875
uniprot id: B8CZZ6
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

373903:HORE RS02490
gene id: 373903:HORE_RS02490
uniprot id: B8D200
names: Subcellular Location Annotation
messages: Cytoplasm

373903:HORE RS01110
gene id: 373903:HORE_RS01110
uniprot id: B8D0Z1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

373903:HORE RS11720
gene id: 373903:HORE_RS11720
uniprot id: B8D0S1
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

373903:HORE RS06120
gene id: 373903:HORE_RS06120
uniprot id: B8CXA1
names: Subcellular Location Annotation
messages: Membrane

373903:HORE RS03725
gene id: 373903:HORE_RS03725
uniprot id: B8CVZ0
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

373903:HORE RS06305
gene id: 373903:HORE_RS06305
uniprot id: B8CXD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit D family.
messages: Membrane

373903:HORE RS02860
gene id: 373903:HORE_RS02860
uniprot id: B8D272
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

373903:HORE RS00835
gene id: 373903:HORE_RS00835
uniprot id: B8D0T7
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

373903:HORE RS12095
gene id: 373903:HORE_RS12095
uniprot id: B8D1C8
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

373903:HORE RS04940
gene id: 373903:HORE_RS04940
uniprot id: B8CWM6
names: Similarity
messages: Belongs to the OMP decarboxylase family. Type 2 subfamily.

373903:HORE RS10045
gene id: 373903:HORE_RS10045
uniprot id: B8CZG8
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit.

373903:HORE RS07960
gene id: 373903:HORE_RS07960
uniprot id: B8CYA8
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

373903:HORE RS02605
gene id: 373903:HORE_RS02605
uniprot id: B8D223
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

373903:HORE RS04090
gene id: 373903:HORE_RS04090
uniprot id: B8CW64
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

373903:HORE RS02590
gene id: 373903:HORE_RS02590
uniprot id: B8D220
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Belongs to the methylglyoxal synthase family.
messages: Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

373903:HORE RS06365
gene id: 373903:HORE_RS06365
uniprot id: B8CXE9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

373903:HORE RS08730
gene id: 373903:HORE_RS08730
uniprot id: B8CYQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

373903:HORE RS04435
gene id: 373903:HORE_RS04435
uniprot id: B8CWD3
names: Subcellular Location Annotation
messages: Membrane

373903:HORE RS06095
gene id: 373903:HORE_RS06095
uniprot id: B8CX96
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Monomer.

373903:HORE RS00745
gene id: 373903:HORE_RS00745
uniprot id: B8D0D4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

373903:HORE RS05705
gene id: 373903:HORE_RS05705
uniprot id: B8CX25
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

373903:HORE RS01120
gene id: 373903:HORE_RS01120
uniprot id: B8D0Z3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

373903:HORE RS03790
gene id: 373903:HORE_RS03790
uniprot id: B8CW04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Cell membrane
messages: Membrane

373903:HORE RS07420
gene id: 373903:HORE_RS07420
uniprot id: B8CY04
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

373903:HORE RS03910
gene id: 373903:HORE_RS03910
uniprot id: B8CW28
names: Similarity
messages: Belongs to the UPF0102 family.

373903:HORE RS01410
gene id: 373903:HORE_RS01410
uniprot id: B8D150
names: Subcellular Location Annotation
messages: Membrane

373903:HORE RS04780
gene id: 373903:HORE_RS04780
uniprot id: B8CWJ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

373903:HORE RS03540
gene id: 373903:HORE_RS03540
uniprot id: B8D2J5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arginine deiminase family.
messages: Cytoplasm

373903:HORE RS03560
gene id: 373903:HORE_RS03560
uniprot id: B8CVV7
names: Subcellular Location Annotation
messages: Membrane

373903:HORE RS02890
gene id: 373903:HORE_RS02890
uniprot id: B8D277
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

373903:HORE RS06710
gene id: 373903:HORE_RS06710
uniprot id: B8CXL7
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Autoproteolytically processed. The inactive tetrameric zymogen termed p46 autoprocesses to a smaller form termed p41, which is active only during spore germination.
messages: Belongs to the peptidase A25 family.
messages: Homotetramer.
messages: Initiates the rapid degradation of small, acid-soluble proteins during spore germination.

373903:HORE RS00320
gene id: 373903:HORE_RS00320
uniprot id: B8D055
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

373903:HORE RS02045
gene id: 373903:HORE_RS02045
uniprot id: B8D1R5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell inner membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

373903:HORE RS01700
gene id: 373903:HORE_RS01700
uniprot id: B8D1K1
names: Similarity
names: Subunit
messages: Belongs to the MtrB family.
messages: Oligomer of 11 identical subunits arranged in doughnut-like structure.

373903:HORE RS02375
gene id: 373903:HORE_RS02375
uniprot id: B8D1X7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

373903:HORE RS12200
gene id: 373903:HORE_RS12200
uniprot id: B8D1E9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

373903:HORE RS01060
gene id: 373903:HORE_RS01060
uniprot id: B8D0Y2
names: Subcellular Location Annotation
messages: Membrane

373903:HORE RS11175
gene id: 373903:HORE_RS11175
uniprot id: B8D0G7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PstS family.
messages: Cell membrane
messages: Involved in the system for phosphate transport across the cytoplasmic membrane.
messages: Membrane
messages: Part of the ABC transporter complex PstSACB involved in phosphate import.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

373903:HORE RS09350
gene id: 373903:HORE_RS09350
uniprot id: B8CZ30
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

373903:HORE RS05530
gene id: 373903:HORE_RS05530
uniprot id: B8CWZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell inner membrane
messages: Probably interacts with PlsX.

373903:HORE RS02070
gene id: 373903:HORE_RS02070
uniprot id: B8D1R9
names: Caution
names: Function
names: Similarity
messages: Belongs to the HypA/HybF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

373903:HORE RS03340
gene id: 373903:HORE_RS03340
uniprot id: B8D2G0
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

373903:HORE RS09135
gene id: 373903:HORE_RS09135
uniprot id: B8CYY6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

373903:HORE RS00900
gene id: 373903:HORE_RS00900
uniprot id: B8D0U9
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

373903:HORE RS11135
gene id: 373903:HORE_RS11135
uniprot id: B8D0F9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

373903:HORE RS08940
gene id: 373903:HORE_RS08940
uniprot id: B8CYU8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LPG synthase family.
messages: Catalyzes the transfer of a lysyl group from L-lysyl-tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms.
messages: Cell membrane
messages: Membrane

373903:HORE RS09120
gene id: 373903:HORE_RS09120
uniprot id: B8CYY3
names: Function
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

373903:HORE RS00785
gene id: 373903:HORE_RS00785
uniprot id: B8D0E2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

373903:HORE RS10060
gene id: 373903:HORE_RS10060
uniprot id: B8CZH1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase C chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

373903:HORE RS01820
gene id: 373903:HORE_RS01820
uniprot id: B8D1M4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic Ku family.
messages: Homodimer. Interacts with LigD.
messages: With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD.

373903:HORE RS11970
gene id: 373903:HORE_RS11970
uniprot id: B8D1A3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

373903:HORE RS05575
gene id: 373903:HORE_RS05575
uniprot id: B8CWZ9
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSP33 family.
messages: Cytoplasm
messages: Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.
messages: Under oxidizing conditions two disulfide bonds are formed involving the reactive cysteines. Under reducing conditions zinc is bound to the reactive cysteines and the protein is inactive.

373903:HORE RS04050
gene id: 373903:HORE_RS04050
uniprot id: B8CW56
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

373903:HORE RS05675
gene id: 373903:HORE_RS05675
uniprot id: B8CX19
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

373903:HORE RS01185
gene id: 373903:HORE_RS01185
uniprot id: B8D106
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protease PrsW family.
messages: Cell membrane
messages: Membrane

373903:HORE RS05760
gene id: 373903:HORE_RS05760
uniprot id: B8CX36
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Could methylate the ribose at the nucleotide 34 wobble position in tRNA.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

373903:HORE RS11615
gene id: 373903:HORE_RS11615
uniprot id: B8D0Q1
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.
messages: Monomer.

373903:HORE RS00690
gene id: 373903:HORE_RS00690
uniprot id: B8D0C3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

373903:HORE RS01755
gene id: 373903:HORE_RS01755
uniprot id: B8D1L3
names: Similarity
messages: Belongs to the transketolase family.

373903:HORE RS11855
gene id: 373903:HORE_RS11855
uniprot id: B8CW01
names: Similarity
messages: Belongs to the UPF0236 family.

373903:HORE RS12280
gene id: 373903:HORE_RS12280
uniprot id: B8D1T0
names: Similarity
messages: Belongs to the zinc-associated anti-sigma factor (ZAS) superfamily. Anti-sigma-W factor family.

373903:HORE RS11165
gene id: 373903:HORE_RS11165
uniprot id: B8D0G5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

373903:HORE RS08330
gene id: 373903:HORE_RS08330
uniprot id: B8CYH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the encapsulin family. Family 1 subfamily.
messages: Encapsulin nanocompartment

373903:HORE RS04225
gene id: 373903:HORE_RS04225
uniprot id: B8CW91
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

373903:HORE RS00685
gene id: 373903:HORE_RS00685
uniprot id: B8D0A8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

373903:HORE RS03270
gene id: 373903:HORE_RS03270
uniprot id: B8D2E6
names: Similarity
messages: Belongs to the SfsA family.

373903:HORE RS12565
gene id: 373903:HORE_RS12565
uniprot id: B8CZL7
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

373903:HORE RS09750
gene id: 373903:HORE_RS09750
uniprot id: B8CZB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

373903:HORE RS09025
gene id: 373903:HORE_RS09025
uniprot id: B8CYW5
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

373903:HORE RS05875
gene id: 373903:HORE_RS05875
uniprot id: B8CX54
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

373903:HORE RS04095
gene id: 373903:HORE_RS04095
uniprot id: B8CW65
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

373903:HORE RS03980
gene id: 373903:HORE_RS03980
uniprot id: B8CW42
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

373903:HORE RS03120
gene id: 373903:HORE_RS03120
uniprot id: B8D2B6
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

373903:HORE RS00465
gene id: 373903:HORE_RS00465
uniprot id: B8D083
names: Similarity
messages: Belongs to the UPF0047 family.

373903:HORE RS09510
gene id: 373903:HORE_RS09510
uniprot id: B8CZ62
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

373903:HORE RS00300
gene id: 373903:HORE_RS00300
uniprot id: B8D050
names: Cofactor
messages: Binds 2 magnesium ions per subunit.

373903:HORE RS11975
gene id: 373903:HORE_RS11975
uniprot id: B8D1A4
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

373903:HORE RS02980
gene id: 373903:HORE_RS02980
uniprot id: B8D288
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

373903:HORE RS08780
gene id: 373903:HORE_RS08780
uniprot id: B8CYR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Cytoplasm

373903:HORE RS11875
gene id: 373903:HORE_RS11875
uniprot id: B8D185
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
messages: Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.

373903:HORE RS00625
gene id: 373903:HORE_RS00625
uniprot id: B8D0B1
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

373903:HORE RS00760
gene id: 373903:HORE_RS00760
uniprot id: B8D0D7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

373903:HORE RS11770
gene id: 373903:HORE_RS11770
uniprot id: B8D165
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.

373903:HORE RS07580
gene id: 373903:HORE_RS07580
uniprot id: B8CY36
names: Similarity
messages: Belongs to the glycosyl hydrolase 65 family.

373903:HORE RS08370
gene id: 373903:HORE_RS08370
uniprot id: B8CYI5
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

373903:HORE RS10690
gene id: 373903:HORE_RS10690
uniprot id: B8CZW1
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

373903:HORE RS08055
gene id: 373903:HORE_RS08055
uniprot id: B8CYC3
names: Similarity
names: Subunit
messages: Belongs to the methylaspartate ammonia-lyase family.
messages: Homodimer.

373903:HORE RS04490
gene id: 373903:HORE_RS04490
uniprot id: B8CWE3
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

373903:HORE RS11275
gene id: 373903:HORE_RS11275
uniprot id: B8D0I6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

373903:HORE RS11840
gene id: 373903:HORE_RS11840
uniprot id: B8D178
names: Subcellular Location Annotation
messages: Membrane

373903:HORE RS10300
gene id: 373903:HORE_RS10300
uniprot id: B8CZL9
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

373903:HORE RS08920
gene id: 373903:HORE_RS08920
uniprot id: B8CYU4
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

373903:HORE RS07455
gene id: 373903:HORE_RS07455
uniprot id: B8CY11
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

373903:HORE RS01715
gene id: 373903:HORE_RS01715
uniprot id: B8D1K5
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homotetramer.

373903:HORE RS09330
gene id: 373903:HORE_RS09330
uniprot id: B8CZ26
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

373903:HORE RS02290
gene id: 373903:HORE_RS02290
uniprot id: B8D1W0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

373903:HORE RS11430
gene id: 373903:HORE_RS11430
uniprot id: B8D0L5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThiI family.
messages: Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
messages: Cytoplasm

373903:HORE RS00680
gene id: 373903:HORE_RS00680
uniprot id: B8D0C1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

373903:HORE RS06170
gene id: 373903:HORE_RS06170
uniprot id: B8CXB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

373903:HORE RS02475
gene id: 373903:HORE_RS02475
uniprot id: B8D1Z7
names: Function
messages: Acetylation of prosthetic group (2-(5''-phosphoribosyl)-3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase.

373903:HORE RS12325
gene id: 373903:HORE_RS12325
uniprot id: B8D248
names: Similarity
messages: Belongs to the peptidase S8 family.

373903:HORE RS11215
gene id: 373903:HORE_RS11215
uniprot id: B8D0H5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

373903:HORE RS05460
gene id: 373903:HORE_RS05460
uniprot id: B8CWX7
names: Domain
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

373903:HORE RS04355
gene id: 373903:HORE_RS04355
uniprot id: B8CWB7
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

373903:HORE RS01615
gene id: 373903:HORE_RS01615
uniprot id: B8D1I4
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

373903:HORE RS00650
gene id: 373903:HORE_RS00650
uniprot id: B8D0B5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

373903:HORE RS11475
gene id: 373903:HORE_RS11475
uniprot id: B8D0M4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

373903:HORE RS01235
gene id: 373903:HORE_RS01235
uniprot id: B8D116
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

373903:HORE RS04555
gene id: 373903:HORE_RS04555
uniprot id: B8CWF6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

373903:HORE RS08240
gene id: 373903:HORE_RS08240
uniprot id: B8CYF9
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

373903:HORE RS04255
gene id: 373903:HORE_RS04255
uniprot id: B8CW97
names: Activity Regulation
names: Function
names: Similarity
names: Subunit
messages: Activated by phosphorylation and inhibited by fructose 1,6-bisphosphate (FBP).
messages: Belongs to the FGGY kinase family.
messages: Homotetramer and homodimer (in equilibrium).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.

373903:HORE RS06525
gene id: 373903:HORE_RS06525
uniprot id: B8CXI0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

373903:HORE RS11330
gene id: 373903:HORE_RS11330
uniprot id: B8D0J7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetokinase family.
messages: Cytoplasm

373903:HORE RS09285
gene id: 373903:HORE_RS09285
uniprot id: B8CZ17
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase A chain family.
messages: Cell inner membrane
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

373903:HORE RS07875
gene id: 373903:HORE_RS07875
uniprot id: B8CY93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CRISPR system Cmr5 family.
messages: Cytoplasm

373903:HORE RS10055
gene id: 373903:HORE_RS10055
uniprot id: B8CZH0
names: Similarity
messages: Belongs to the V-ATPase F subunit family.

373903:HORE RS07920
gene id: 373903:HORE_RS07920
uniprot id: B8CYA0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

373903:HORE RS07730
gene id: 373903:HORE_RS07730
uniprot id: B8CY66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NADH dehydrogenase family.
messages: Membrane

373903:HORE RS02030
gene id: 373903:HORE_RS02030
uniprot id: B8D1R2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmC/CycZ/HelC family.
messages: Membrane

373903:HORE RS08270
gene id: 373903:HORE_RS08270
uniprot id: B8CYG5
names: Similarity
messages: Belongs to the sigma-54 factor family.

373903:HORE RS09410
gene id: 373903:HORE_RS09410
uniprot id: B8CZ42
names: Similarity
messages: Belongs to the thioredoxin family.

373903:HORE RS05135
gene id: 373903:HORE_RS05135
uniprot id: B8CWR4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell inner membrane
messages: Membrane

373903:HORE RS04920
gene id: 373903:HORE_RS04920
uniprot id: B8CWM2
names: Function
names: Similarity
names: Subunit
messages: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
messages: Homodimer and homohexamer; in equilibrium.
messages: Regulates transcriptional attenuation of the pyrimidine nucleotide (pyr) operon by binding in a uridine-dependent manner to specific sites on pyr mRNA. This disrupts an antiterminator hairpin in the RNA and favors formation of a downstream transcription terminator, leading to a reduced expression of downstream genes.

373903:HORE RS02830
gene id: 373903:HORE_RS02830
uniprot id: B8D267
names: Subcellular Location Annotation
messages: Membrane

373903:HORE RS06020
gene id: 373903:HORE_RS06020
uniprot id: B8CX82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

373903:HORE RS11200
gene id: 373903:HORE_RS11200
uniprot id: B8D0H2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PstS family.
messages: Cell membrane
messages: Involved in the system for phosphate transport across the cytoplasmic membrane.
messages: Membrane
messages: Part of the ABC transporter complex PstSACB involved in phosphate import.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

373903:HORE RS08540
gene id: 373903:HORE_RS08540
uniprot id: B8CYL9
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 26 family. TagA/TarA subfamily.
messages: Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid.

373903:HORE RS01600
gene id: 373903:HORE_RS01600
uniprot id: B8D1I1
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

373903:HORE RS05070
gene id: 373903:HORE_RS05070
uniprot id: B8CWQ1
names: Similarity
messages: Belongs to the metallo-beta-lactamase superfamily. Class-B beta-lactamase family.

373903:HORE RS04210
gene id: 373903:HORE_RS04210
uniprot id: B8CW88
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

373903:HORE RS07830
gene id: 373903:HORE_RS07830
uniprot id: B8CY84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

373903:HORE RS02060
gene id: 373903:HORE_RS02060
uniprot id: B8D1R7
names: Similarity
names: Subunit
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family.
messages: Heterodimer of a large and a small subunit.

373903:HORE RS10535
gene id: 373903:HORE_RS10535
uniprot id: B8CZT1
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

373903:HORE RS01240
gene id: 373903:HORE_RS01240
uniprot id: B8D117
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the PRA-PH family.
messages: In the N-terminal section; belongs to the PRA-CH family.

373903:HORE RS01945
gene id: 373903:HORE_RS01945
uniprot id: B8D1P6
names: Function
names: Similarity
messages: Belongs to the 'phage' integrase family.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

373903:HORE RS11420
gene id: 373903:HORE_RS11420
uniprot id: B8D0L3
names: Subcellular Location Annotation
messages: Membrane

373903:HORE RS00580
gene id: 373903:HORE_RS00580
uniprot id: B8D0A2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

373903:HORE RS02360
gene id: 373903:HORE_RS02360
uniprot id: B8D1X4
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

373903:HORE RS08160
gene id: 373903:HORE_RS08160
uniprot id: B8CYE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0014 family.
messages: Membrane

373903:HORE RS09000
gene id: 373903:HORE_RS09000
uniprot id: B8CYW0
names: Similarity
messages: Belongs to the glutamate synthase family.

373903:HORE RS00295
gene id: 373903:HORE_RS00295
uniprot id: B8D049
names: Similarity
messages: Belongs to the glycosyl hydrolase 65 family.

373903:HORE RS09485
gene id: 373903:HORE_RS09485
uniprot id: B8CZ57
names: Similarity
messages: Belongs to the UPF0251 family.

373903:HORE RS06510
gene id: 373903:HORE_RS06510
uniprot id: B8CXH6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

373903:HORE RS09345
gene id: 373903:HORE_RS09345
uniprot id: B8CZ29
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.

373903:HORE RS09725
gene id: 373903:HORE_RS09725
uniprot id: B8CZA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

373903:HORE RS05360
gene id: 373903:HORE_RS05360
uniprot id: B8CWV7
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

373903:HORE RS09515
gene id: 373903:HORE_RS09515
uniprot id: B8CZ63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

373903:HORE RS09290
gene id: 373903:HORE_RS09290
uniprot id: B8CZ18
names: Subcellular Location Annotation
messages: Membrane

373903:HORE RS01205
gene id: 373903:HORE_RS01205
uniprot id: B8D110
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
messages: This function is generally fulfilled by the C-terminal part of HisG, which is missing in some bacteria such as this one.

373903:HORE RS11280
gene id: 373903:HORE_RS11280
uniprot id: B8D0I7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0756 family.
messages: Cell membrane

373903:HORE RS12115
gene id: 373903:HORE_RS12115
uniprot id: B8D1D2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

373903:HORE RS04110
gene id: 373903:HORE_RS04110
uniprot id: B8CW68
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. DnaE subfamily.
messages: Belongs to the DNA polymerase type-C family. PolC subfamily.
messages: Cytoplasm
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The alpha chain is the DNA polymerase.
messages: Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

373903:HORE RS08285
gene id: 373903:HORE_RS08285
uniprot id: B8CYG8
names: Function
names: Similarity
messages: Belongs to the RapZ-like family.
messages: Displays ATPase and GTPase activities.

373903:HORE RS10845
gene id: 373903:HORE_RS10845
uniprot id: B8CZY9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell inner membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

373903:HORE RS01390
gene id: 373903:HORE_RS01390
uniprot id: B8D146
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

373903:HORE RS05740
gene id: 373903:HORE_RS05740
uniprot id: B8CX32
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic riboflavin transporter (P-RFT) (TC 2.A.87) family.
messages: Cell membrane
messages: Membrane
messages: Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex.

373903:HORE RS09565
gene id: 373903:HORE_RS09565
uniprot id: B8CZ73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

373903:HORE RS10280
gene id: 373903:HORE_RS10280
uniprot id: B8CZL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

373903:HORE RS05645
gene id: 373903:HORE_RS05645
uniprot id: B8CX13
names: Similarity
messages: Belongs to the 5'(3')-deoxyribonucleotidase family.

373903:HORE RS02705
gene id: 373903:HORE_RS02705
uniprot id: B8D243
names: Subcellular Location Annotation
messages: Membrane

373903:HORE RS06430
gene id: 373903:HORE_RS06430
uniprot id: B8CXG2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

373903:HORE RS03490
gene id: 373903:HORE_RS03490
uniprot id: B8D2I5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

373903:HORE RS11435
gene id: 373903:HORE_RS11435
uniprot id: B8D0L6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

373903:HORE RS08495
gene id: 373903:HORE_RS08495
uniprot id: B8CYL0
names: Similarity
messages: Belongs to the glutamate synthase family.

373903:HORE RS06415
gene id: 373903:HORE_RS06415
uniprot id: B8CXF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

373903:HORE RS11250
gene id: 373903:HORE_RS11250
uniprot id: B8D0I2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

373903:HORE RS08070
gene id: 373903:HORE_RS08070
uniprot id: B8CYC6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the methylaspartate mutase GlmS subunit family.
messages: Catalyzes the carbon skeleton rearrangement of L-glutamate to L-threo-3-methylaspartate ((2S,3S)-3-methylaspartate).
messages: Heterotetramer composed of 2 epsilon subunits (GlmE) and 2 sigma subunits (GlmS). GlmE exists as a homodimer and GlmS as a monomer.

373903:HORE RS00655
gene id: 373903:HORE_RS00655
uniprot id: B8D0B6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

373903:HORE RS10495
gene id: 373903:HORE_RS10495
uniprot id: B8CZS3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

373903:HORE RS11820
gene id: 373903:HORE_RS11820
uniprot id: B8D174
names: Subcellular Location Annotation
messages: Membrane

373903:HORE RS10590
gene id: 373903:HORE_RS10590
uniprot id: B8CZU2
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

373903:HORE RS03065
gene id: 373903:HORE_RS03065
uniprot id: B8D2A5
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

373903:HORE RS01980
gene id: 373903:HORE_RS01980
uniprot id: B8D1Q2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Membrane

373903:HORE RS09960
gene id: 373903:HORE_RS09960
uniprot id: B8CZF0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCH family.
messages: Catalyzes the hydrolysis of methenyl-H(4)MPT(+) to 5-formyl-H(4)MPT.
messages: Cytoplasm

373903:HORE RS01970
gene id: 373903:HORE_RS01970
uniprot id: B8D1Q1
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

373903:HORE RS00850
gene id: 373903:HORE_RS00850
uniprot id: B8D0U0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex.
messages: Belongs to the ABC transporter superfamily. Energy-coupling factor EcfA family.
messages: Cell membrane
messages: Forms a stable energy-coupling factor (ECF) transporter complex composed of 2 membrane-embedded substrate-binding proteins (S component), 2 ATP-binding proteins (A component) and 2 transmembrane proteins (T component).
messages: Membrane

373903:HORE RS09815
gene id: 373903:HORE_RS09815
uniprot id: B8CZC2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

373903:HORE RS08255
gene id: 373903:HORE_RS08255
uniprot id: B8CYG2
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

373903:HORE RS07770
gene id: 373903:HORE_RS07770
uniprot id: B8CY74
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

373903:HORE RS03865
gene id: 373903:HORE_RS03865
uniprot id: B8CW19
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpB which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpB.

373903:HORE RS09880
gene id: 373903:HORE_RS09880
uniprot id: B8CZD5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

373903:HORE RS03480
gene id: 373903:HORE_RS03480
uniprot id: B8D2I3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

373903:HORE RS01750
gene id: 373903:HORE_RS01750
uniprot id: B8D1L2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 3B subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

373903:HORE RS08575
gene id: 373903:HORE_RS08575
uniprot id: B8CYM6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

373903:HORE RS02075
gene id: 373903:HORE_RS02075
uniprot id: B8D1S0
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily.

373903:HORE RS08840
gene id: 373903:HORE_RS08840
uniprot id: B8CYS8
names: Similarity
messages: Belongs to the polysaccharide synthase family.

373903:HORE RS00010
gene id: 373903:HORE_RS00010
uniprot id: B8CZN5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

373903:HORE RS08510
gene id: 373903:HORE_RS08510
uniprot id: B8CYL3
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

373903:HORE RS11780
gene id: 373903:HORE_RS11780
uniprot id: B8D167
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

373903:HORE RS03585
gene id: 373903:HORE_RS03585
uniprot id: B8CVW2
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

373903:HORE RS04070
gene id: 373903:HORE_RS04070
uniprot id: B8CW60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

373903:HORE RS02540
gene id: 373903:HORE_RS02540
uniprot id: B8D210
names: Similarity
messages: Belongs to the OsmC/Ohr family.

373903:HORE RS05670
gene id: 373903:HORE_RS05670
uniprot id: B8CX18
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

373903:HORE RS04900
gene id: 373903:HORE_RS04900
uniprot id: B8CWL8
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: In the native structure, TdcB is in a dimeric form, whereas in the TdcB-AMP complex, it exists in a tetrameric form (dimer of dimers).

373903:HORE RS08215
gene id: 373903:HORE_RS08215
uniprot id: B8CYF3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

373903:HORE RS07495
gene id: 373903:HORE_RS07495
uniprot id: B8CY19
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

373903:HORE RS03185
gene id: 373903:HORE_RS03185
uniprot id: B8D2C9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell inner membrane
messages: Cell membrane
messages: Component of the type II secretion system inner membrane complex required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.
messages: Membrane

373903:HORE RS00940
gene id: 373903:HORE_RS00940
uniprot id: B8D0V7
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

373903:HORE RS10285
gene id: 373903:HORE_RS10285
uniprot id: B8CZL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

373903:HORE RS11125
gene id: 373903:HORE_RS11125
uniprot id: B8D0F7
names: Function
names: Similarity
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

373903:HORE RS04860
gene id: 373903:HORE_RS04860
uniprot id: B8CWL0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SepF family.
messages: Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

373903:HORE RS12020
gene id: 373903:HORE_RS12020
uniprot id: B8D1B3
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

373903:HORE RS09240
gene id: 373903:HORE_RS09240
uniprot id: B8CZ07
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm

373903:HORE RS00985
gene id: 373903:HORE_RS00985
uniprot id: B8D0W7
names: Function
names: Similarity
messages: Belongs to the PemK/MazF family.
messages: Toxic component of a type II toxin-antitoxin (TA) system.

373903:HORE RS01565
gene id: 373903:HORE_RS01565
uniprot id: B8D1H4
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

373903:HORE RS06895
gene id: 373903:HORE_RS06895
uniprot id: B8CXQ5
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

373903:HORE RS12080
gene id: 373903:HORE_RS12080
uniprot id: B8D1C5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

373903:HORE RS08060
gene id: 373903:HORE_RS08060
uniprot id: B8CYC4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the methylaspartate mutase GlmE subunit family.
messages: Catalyzes the carbon skeleton rearrangement of L-glutamate to L-threo-3-methylaspartate ((2S,3S)-3-methylaspartate).
messages: Heterotetramer composed of 2 epsilon subunits (GlmE) and 2 sigma subunits (GlmS). GlmE exists as a homodimer and GlmS as a monomer.

373903:HORE RS03550
gene id: 373903:HORE_RS03550
uniprot id: B8D2J7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Basic amino acid/polyamine antiporter (APA) (TC 2.A.3.2) family.
messages: Membrane

373903:HORE RS11905
gene id: 373903:HORE_RS11905
uniprot id: B8D191
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

373903:HORE RS08880
gene id: 373903:HORE_RS08880
uniprot id: B8CYT6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum
messages: Belongs to the FliD family.
messages: Homopentamer.
messages: Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Secreted

373903:HORE RS08690
gene id: 373903:HORE_RS08690
uniprot id: B8CYP9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell inner membrane
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

373903:HORE RS01015
gene id: 373903:HORE_RS01015
uniprot id: B8D0X3
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

373903:HORE RS12070
gene id: 373903:HORE_RS12070
uniprot id: B8D1C3
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 4 family.
messages: Binds 1 NAD(+) per subunit.
messages: Homotetramer.

373903:HORE RS10990
gene id: 373903:HORE_RS10990
uniprot id: B8D014
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

373903:HORE RS04745
gene id: 373903:HORE_RS04745
uniprot id: B8CWI7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

373903:HORE RS08420
gene id: 373903:HORE_RS08420
uniprot id: B8CYJ5
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

373903:HORE RS02695
gene id: 373903:HORE_RS02695
uniprot id: B8D241
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Homotetramer.

373903:HORE RS01400
gene id: 373903:HORE_RS01400
uniprot id: B8D148
names: Subcellular Location Annotation
messages: Membrane

373903:HORE RS11800
gene id: 373903:HORE_RS11800
uniprot id: B8D170
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

373903:HORE RS05000
gene id: 373903:HORE_RS05000
uniprot id: B8CWN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

373903:HORE RS00710
gene id: 373903:HORE_RS00710
uniprot id: B8D0C7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

373903:HORE RS11295
gene id: 373903:HORE_RS11295
uniprot id: B8D0J0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 3B subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

373903:HORE RS10450
gene id: 373903:HORE_RS10450
uniprot id: B8CZR4
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

373903:HORE RS04065
gene id: 373903:HORE_RS04065
uniprot id: B8CW59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

373903:HORE RS09895
gene id: 373903:HORE_RS09895
uniprot id: B8CZD8
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

373903:HORE RS06055
gene id: 373903:HORE_RS06055
uniprot id: B8CX89
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. LL-diaminopimelate aminotransferase subfamily.
messages: Homodimer.
messages: Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate.

373903:HORE RS00020
gene id: 373903:HORE_RS00020
uniprot id: B8CZN7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

373903:HORE RS11635
gene id: 373903:HORE_RS11635
uniprot id: B8D0Q5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

373903:HORE RS00060
gene id: 373903:HORE_RS00060
uniprot id: B8CZP5
names: Similarity
messages: Belongs to the GerABKC lipoprotein family.

373903:HORE RS08260
gene id: 373903:HORE_RS08260
uniprot id: B8CYG3
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

373903:HORE RS00975
gene id: 373903:HORE_RS00975
uniprot id: B8D0W4
names: Similarity
messages: Belongs to the DNA2/NAM7 helicase family.

373903:HORE RS08280
gene id: 373903:HORE_RS08280
uniprot id: B8CYG7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gluconeogenesis factor family.
messages: Cytoplasm
messages: Required for morphogenesis under gluconeogenic growth conditions.

373903:HORE RS00800
gene id: 373903:HORE_RS00800
uniprot id: B8D0T0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

373903:HORE RS05250
gene id: 373903:HORE_RS05250
uniprot id: B8CWT6
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

373903:HORE RS10975
gene id: 373903:HORE_RS10975
uniprot id: B8D011
names: Subcellular Location Annotation
messages: Membrane

373903:HORE RS04660
gene id: 373903:HORE_RS04660
uniprot id: B8CWH5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
messages: Cytoplasm
messages: Homodimer. Forms a heterotetramer with IscU, interacts with other sulfur acceptors.
messages: Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.

373903:HORE RS06965
gene id: 373903:HORE_RS06965
uniprot id: B8CXR9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein L14 (rplN).

373903:HORE RS00695
gene id: 373903:HORE_RS00695
uniprot id: B8D0C4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

373903:HORE RS00815
gene id: 373903:HORE_RS00815
uniprot id: B8D0T3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

373903:HORE RS07750
gene id: 373903:HORE_RS07750
uniprot id: B8CY70
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

373903:HORE RS08275
gene id: 373903:HORE_RS08275
uniprot id: B8CYG6
names: Function
names: Similarity
messages: Belongs to the WhiA family.
messages: Involved in cell division and chromosome segregation.

373903:HORE RS05475
gene id: 373903:HORE_RS05475
uniprot id: B8CWY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

373903:HORE RS04670
gene id: 373903:HORE_RS04670
uniprot id: B8CWH7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm

373903:HORE RS04000
gene id: 373903:HORE_RS04000
uniprot id: B8CW46
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CodY family.
messages: Cytoplasm
messages: DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor.

373903:HORE RS03915
gene id: 373903:HORE_RS03915
uniprot id: B8CW29
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

373903:HORE RS01810
gene id: 373903:HORE_RS01810
uniprot id: B8D1M2
names: Similarity
messages: Belongs to the peptidase S16 family.

373903:HORE RS05295
gene id: 373903:HORE_RS05295
uniprot id: B8CWU4
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

373903:HORE RS07450
gene id: 373903:HORE_RS07450
uniprot id: B8CY10
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.
messages: Binds 3 [4Fe-4S] clusters.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

373903:HORE RS11005
gene id: 373903:HORE_RS11005
uniprot id: B8D017
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

373903:HORE RS07675
gene id: 373903:HORE_RS07675
uniprot id: B8CY55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

373903:HORE RS02725
gene id: 373903:HORE_RS02725
uniprot id: B8D247
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

373903:HORE RS04705
gene id: 373903:HORE_RS04705
uniprot id: B8CWH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

373903:HORE RS11550
gene id: 373903:HORE_RS11550
uniprot id: B8D0N8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

373903:HORE RS06695
gene id: 373903:HORE_RS06695
uniprot id: B8CXL4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

373903:HORE RS04825
gene id: 373903:HORE_RS04825
uniprot id: B8CWK3
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

373903:HORE RS00030
gene id: 373903:HORE_RS00030
uniprot id: B8CZN9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

373903:HORE RS00905
gene id: 373903:HORE_RS00905
uniprot id: B8D0V0
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

373903:HORE RS06485
gene id: 373903:HORE_RS06485
uniprot id: B8CXH1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

373903:HORE RS02850
gene id: 373903:HORE_RS02850
uniprot id: B8D271
names: Subcellular Location Annotation
messages: Cytoplasm

373903:HORE RS05330
gene id: 373903:HORE_RS05330
uniprot id: B8CWV1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

373903:HORE RS03660
gene id: 373903:HORE_RS03660
uniprot id: B8CVX7
names: Similarity
messages: Belongs to the peptidase M29 family.

373903:HORE RS11700
gene id: 373903:HORE_RS11700
uniprot id: B8D0R7
names: Function
names: Similarity
messages: Belongs to the CheD family.
messages: Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.

373903:HORE RS04160
gene id: 373903:HORE_RS04160
uniprot id: B8CW78
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

373903:HORE RS05205
gene id: 373903:HORE_RS05205
uniprot id: B8CWS7
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

373903:HORE RS04120
gene id: 373903:HORE_RS04120
uniprot id: B8CW70
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

373903:HORE RS01690
gene id: 373903:HORE_RS01690
uniprot id: B8D1J9
names: Similarity
messages: Belongs to the class-II fumarase/aspartase family. Aspartase subfamily.

373903:HORE RS05570
gene id: 373903:HORE_RS05570
uniprot id: B8CWZ8
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

373903:HORE RS02815
gene id: 373903:HORE_RS02815
uniprot id: B8D265
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

373903:HORE RS01275
gene id: 373903:HORE_RS01275
uniprot id: B8D124
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

373903:HORE RS01040
gene id: 373903:HORE_RS01040
uniprot id: B8D0X8
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

373903:HORE RS06240
gene id: 373903:HORE_RS06240
uniprot id: B8CXC7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane
messages: This protein catalyzes the committed step to the synthesis of the acidic phospholipids.

373903:HORE RS09525
gene id: 373903:HORE_RS09525
uniprot id: B8CZ65
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

373903:HORE RS02090
gene id: 373903:HORE_RS02090
uniprot id: B8D1S3
names: Similarity
messages: Belongs to the HypD family.

373903:HORE RS03590
gene id: 373903:HORE_RS03590
uniprot id: B8CVW3
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

373903:HORE RS03795
gene id: 373903:HORE_RS03795
uniprot id: B8CW05
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ScpA family.
messages: Component of a cohesin-like complex composed of ScpA, ScpB and the Smc homodimer, in which ScpA and ScpB bind to the head domain of Smc. The presence of the three proteins is required for the association of the complex with DNA.
messages: Cytoplasm
messages: Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.

373903:HORE RS03265
gene id: 373903:HORE_RS03265
uniprot id: B8D2E5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

373903:HORE RS09715
gene id: 373903:HORE_RS09715
uniprot id: B8CZA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

373903:HORE RS01170
gene id: 373903:HORE_RS01170
uniprot id: B8D103
names: Similarity
messages: In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
messages: In the N-terminal section; belongs to the aldehyde dehydrogenase family.

373903:HORE RS11055
gene id: 373903:HORE_RS11055
uniprot id: B8D0E3
names: Similarity
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.

373903:HORE RS12560
gene id: 373903:HORE_RS12560
uniprot id: B8CZH5
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

373903:HORE RS01720
gene id: 373903:HORE_RS01720
uniprot id: B8D1K6
names: Similarity
messages: Belongs to the pyruvate kinase family.
messages: In the C-terminal section; belongs to the PEP-utilizing enzyme family.

373903:HORE RS06330
gene id: 373903:HORE_RS06330
uniprot id: B8CXE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

373903:HORE RS10065
gene id: 373903:HORE_RS10065
uniprot id: B8CZH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Membrane

373903:HORE RS03060
gene id: 373903:HORE_RS03060
uniprot id: B8D2A4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

373903:HORE RS05775
gene id: 373903:HORE_RS05775
uniprot id: B8CX38
names: Similarity
messages: Belongs to the organic radical-activating enzymes family.

373903:HORE RS09970
gene id: 373903:HORE_RS09970
uniprot id: B8CZF2
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

373903:HORE RS09975
gene id: 373903:HORE_RS09975
uniprot id: B8CZF3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

373903:HORE RS06720
gene id: 373903:HORE_RS06720
uniprot id: B8CXL9
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

373903:HORE RS10575
gene id: 373903:HORE_RS10575
uniprot id: B8CZT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

373903:HORE RS04340
gene id: 373903:HORE_RS04340
uniprot id: B8CWB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM19 family.
messages: Membrane

373903:HORE RS04045
gene id: 373903:HORE_RS04045
uniprot id: B8CW55
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by GTP. Inhibited by UTP.
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

373903:HORE RS05320
gene id: 373903:HORE_RS05320
uniprot id: B8CWU9
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

373903:HORE RS09100
gene id: 373903:HORE_RS09100
uniprot id: B8CYX9
names: Subcellular Location Annotation
messages: Membrane

373903:HORE RS08265
gene id: 373903:HORE_RS08265
uniprot id: B8CYG4
names: Similarity
messages: Belongs to the SorC transcriptional regulatory family.

373903:HORE RS05300
gene id: 373903:HORE_RS05300
uniprot id: B8CWU5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

373903:HORE RS06570
gene id: 373903:HORE_RS06570
uniprot id: B8CXI9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

373903:HORE RS01030
gene id: 373903:HORE_RS01030
uniprot id: B8D0X6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

373903:HORE RS08895
gene id: 373903:HORE_RS08895
uniprot id: B8CYT9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

373903:HORE RS07145
gene id: 373903:HORE_RS07145
uniprot id: B8CXV4
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

373903:HORE RS04605
gene id: 373903:HORE_RS04605
uniprot id: B8CWG7
names: Subcellular Location Annotation
messages: Membrane

373903:HORE RS02295
gene id: 373903:HORE_RS02295
uniprot id: B8D1W2
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

373903:HORE RS02925
gene id: 373903:HORE_RS02925
uniprot id: B8D283
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

373903:HORE RS08740
gene id: 373903:HORE_RS08740
uniprot id: B8CYQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

373903:HORE RS06475
gene id: 373903:HORE_RS06475
uniprot id: B8CXH0
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

373903:HORE RS11650
gene id: 373903:HORE_RS11650
uniprot id: B8D0Q8
names: Cofactor
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.

373903:HORE RS08695
gene id: 373903:HORE_RS08695
uniprot id: B8CYQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type III secretion exporter family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

373903:HORE RS10505
gene id: 373903:HORE_RS10505
uniprot id: B8CZS5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

373903:HORE RS06405
gene id: 373903:HORE_RS06405
uniprot id: B8CXF7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

373903:HORE RS00840
gene id: 373903:HORE_RS00840
uniprot id: B8D0T8
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

373903:HORE RS07570
gene id: 373903:HORE_RS07570
uniprot id: B8CY34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

373903:HORE RS02800
gene id: 373903:HORE_RS02800
uniprot id: B8D261
names: Function
names: Similarity
messages: Belongs to the desulfoferrodoxin family.
messages: Catalyzes the one-electron reduction of superoxide anion radical to hydrogen peroxide at a nonheme ferrous iron center. Plays a fundamental role in case of oxidative stress via its superoxide detoxification activity.

373903:HORE RS00565
gene id: 373903:HORE_RS00565
uniprot id: B8D099
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

373903:HORE RS00780
gene id: 373903:HORE_RS00780
uniprot id: B8D0E1
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

373903:HORE RS08835
gene id: 373903:HORE_RS08835
uniprot id: B8CYS7
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

373903:HORE RS10680
gene id: 373903:HORE_RS10680
uniprot id: B8CZV9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. GalK subfamily.
messages: Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P).
messages: Cytoplasm

373903:HORE RS10015
gene id: 373903:HORE_RS10015
uniprot id: B8CZG2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

373903:HORE RS05810
gene id: 373903:HORE_RS05810
uniprot id: B8CX42
names: Function
names: Similarity
messages: Belongs to the 'phage' integrase family.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

373903:HORE RS10735
gene id: 373903:HORE_RS10735
uniprot id: B8CZX0
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

373903:HORE RS00675
gene id: 373903:HORE_RS00675
uniprot id: B8D0C0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

373903:HORE RS06680
gene id: 373903:HORE_RS06680
uniprot id: B8CXL1
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

373903:HORE RS03820
gene id: 373903:HORE_RS03820
uniprot id: B8CW10
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

373903:HORE RS09305
gene id: 373903:HORE_RS09305
uniprot id: B8CZ21
names: Subcellular Location Annotation
messages: Membrane

373903:HORE RS03455
gene id: 373903:HORE_RS03455
uniprot id: B8D2H9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

373903:HORE RS12000
gene id: 373903:HORE_RS12000
uniprot id: B8D1A9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm

373903:HORE RS12210
gene id: 373903:HORE_RS12210
uniprot id: B8D1F1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OXA1/ALB3/YidC family.
messages: Membrane

373903:HORE RS03995
gene id: 373903:HORE_RS03995
uniprot id: B8CW45
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

373903:HORE RS10130
gene id: 373903:HORE_RS10130
uniprot id: B8CZI5
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

373903:HORE RS06675
gene id: 373903:HORE_RS06675
uniprot id: B8CXL0
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

373903:HORE RS02035
gene id: 373903:HORE_RS02035
uniprot id: B8D1R3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell inner membrane
messages: Forms a complex with TatA.
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.

373903:HORE RS08290
gene id: 373903:HORE_RS08290
uniprot id: B8CYG9
names: Similarity
messages: Belongs to the diacylglycerol/lipid kinase family.

373903:HORE RS01730
gene id: 373903:HORE_RS01730
uniprot id: B8D1K8
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

373903:HORE RS03325
gene id: 373903:HORE_RS03325
uniprot id: B8D2F7
names: Similarity
messages: Belongs to the asp23 family.

373903:HORE RS07595
gene id: 373903:HORE_RS07595
uniprot id: B8CY39
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

373903:HORE RS04150
gene id: 373903:HORE_RS04150
uniprot id: B8CW76
names: Similarity
messages: Belongs to the ribF family.

373903:HORE RS03705
gene id: 373903:HORE_RS03705
uniprot id: B8CVY6
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

373903:HORE RS02500
gene id: 373903:HORE_RS02500
uniprot id: B8D202
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

373903:HORE RS10685
gene id: 373903:HORE_RS10685
uniprot id: B8CZW0
names: Cofactor
names: Similarity
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.
messages: Binds 1 zinc ion per subunit.

373903:HORE RS09695
gene id: 373903:HORE_RS09695
uniprot id: B8CZA0
names: Similarity
messages: Belongs to the GSP E family.

373903:HORE RS09265
gene id: 373903:HORE_RS09265
uniprot id: B8CZ12
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

373903:HORE RS11210
gene id: 373903:HORE_RS11210
uniprot id: B8D0H4
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

373903:HORE RS12530
gene id: 373903:HORE_RS12530
uniprot id: B8CYZ1
names: Subcellular Location Annotation
messages: Membrane

373903:HORE RS12355
gene id: 373903:HORE_RS12355
uniprot id: B8D2H0
names: Similarity
messages: Belongs to the peptidase S8 family.

373903:HORE RS10465
gene id: 373903:HORE_RS10465
uniprot id: B8CZR7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

373903:HORE RS04410
gene id: 373903:HORE_RS04410
uniprot id: B8CWC8
names: Function
names: Similarity
messages: Belongs to the glutamate--cysteine ligase type 2 family. EgtA subfamily.
messages: Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC).

373903:HORE RS04500
gene id: 373903:HORE_RS04500
uniprot id: B8CWE5
names: Similarity
messages: Belongs to the UPF0236 family.

373903:HORE RS07585
gene id: 373903:HORE_RS07585
uniprot id: B8CY37
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MenA family. Type 1 subfamily.
messages: Cell inner membrane
messages: Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).
messages: Membrane

373903:HORE RS08685
gene id: 373903:HORE_RS08685
uniprot id: B8CYP8
names: Function
names: Similarity
messages: Belongs to the GTP-binding SRP family.
messages: Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum.

373903:HORE RS11695
gene id: 373903:HORE_RS11695
uniprot id: B8D0R6
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

373903:HORE RS09920
gene id: 373903:HORE_RS09920
uniprot id: B8CZE2
names: Subcellular Location Annotation
messages: Membrane

373903:HORE RS04845
gene id: 373903:HORE_RS04845
uniprot id: B8CWK7
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

373903:HORE RS11020
gene id: 373903:HORE_RS11020
uniprot id: B8D020
names: Similarity
messages: Belongs to the HypE family.

373903:HORE RS04485
gene id: 373903:HORE_RS04485
uniprot id: B8CWE2
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

373903:HORE RS10815
gene id: 373903:HORE_RS10815
uniprot id: B8CZY4
names: Subcellular Location Annotation
messages: Membrane

373903:HORE RS03990
gene id: 373903:HORE_RS03990
uniprot id: B8CW44
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

373903:HORE RS00570
gene id: 373903:HORE_RS00570
uniprot id: B8D0A0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).

373903:HORE RS11360
gene id: 373903:HORE_RS11360
uniprot id: B8D0K3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

373903:HORE RS08455
gene id: 373903:HORE_RS08455
uniprot id: B8CYK2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

373903:HORE RS06630
gene id: 373903:HORE_RS06630
uniprot id: B8CXK1
names: Similarity
messages: Belongs to the FBPase class 2 family.

373903:HORE RS02230
gene id: 373903:HORE_RS02230
uniprot id: B8D1U9
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

373903:HORE RS01560
gene id: 373903:HORE_RS01560
uniprot id: B8D1H3
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

373903:HORE RS12005
gene id: 373903:HORE_RS12005
uniprot id: B8D1B0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycyl radical enzyme (GRE) family. PFL subfamily.
messages: Cytoplasm
messages: Homodimer.

373903:HORE RS03895
gene id: 373903:HORE_RS03895
uniprot id: B8CW25
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

373903:HORE RS02480
gene id: 373903:HORE_RS02480
uniprot id: B8D1Z8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CitD family.
messages: Covalent carrier of the coenzyme of citrate lyase.
messages: Cytoplasm
messages: Oligomer with a subunit composition of (alpha,beta,gamma)6.

373903:HORE RS06060
gene id: 373903:HORE_RS06060
uniprot id: B8CX90
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.

373903:HORE RS09875
gene id: 373903:HORE_RS09875
uniprot id: B8CZD4
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

373903:HORE RS06595
gene id: 373903:HORE_RS06595
uniprot id: B8CXJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

373903:HORE RS02575
gene id: 373903:HORE_RS02575
uniprot id: B8D217
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

373903:HORE RS09360
gene id: 373903:HORE_RS09360
uniprot id: B8CZ32
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

373903:HORE RS11425
gene id: 373903:HORE_RS11425
uniprot id: B8D0L4
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

373903:HORE RS11150
gene id: 373903:HORE_RS11150
uniprot id: B8D0G2
names: Cofactor
messages: Binds 1 zinc ion per subunit.

373903:HORE RS04875
gene id: 373903:HORE_RS04875
uniprot id: B8CWL3
names: Subcellular Location Annotation
messages: Cytoplasm

373903:HORE RS11305
gene id: 373903:HORE_RS11305
uniprot id: B8D0J2
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

373903:HORE RS04075
gene id: 373903:HORE_RS04075
uniprot id: B8CW61
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).

373903:HORE RS05470
gene id: 373903:HORE_RS05470
uniprot id: B8CWX9
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

373903:HORE RS04135
gene id: 373903:HORE_RS04135
uniprot id: B8CW73
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

373903:HORE RS07440
gene id: 373903:HORE_RS07440
uniprot id: B8CY08
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ApbE family.
messages: Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.
messages: Magnesium. Can also use manganese.

373903:HORE RS05080
gene id: 373903:HORE_RS05080
uniprot id: B8CWQ3
names: Similarity
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family. Bacterial alpha-2-macroglobulin subfamily.

373903:HORE RS07930
gene id: 373903:HORE_RS07930
uniprot id: B8CYA2
names: Similarity
messages: In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.
messages: In the central section; belongs to the CRISPR-associated helicase Cas3 family.

373903:HORE RS01525
gene id: 373903:HORE_RS01525
uniprot id: B8D1G6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

373903:HORE RS06750
gene id: 373903:HORE_RS06750
uniprot id: B8CXM5
names: Similarity
messages: Belongs to the EamA transporter family.

373903:HORE RS00385
gene id: 373903:HORE_RS00385
uniprot id: B8D067
names: Similarity
messages: Belongs to the formate--tetrahydrofolate ligase family.

373903:HORE RS10550
gene id: 373903:HORE_RS10550
uniprot id: B8CZT4
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

373903:HORE RS07355
gene id: 373903:HORE_RS07355
uniprot id: B8CXZ1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

373903:HORE RS07925
gene id: 373903:HORE_RS07925
uniprot id: B8CYA1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

373903:HORE RS00050
gene id: 373903:HORE_RS00050
uniprot id: B8CZP3
names: Similarity
messages: Belongs to the GerABKA family.

373903:HORE RS07545
gene id: 373903:HORE_RS07545
uniprot id: B8CY29
names: Function
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I. Phospho-HPr then transfers it to the PTS EIIA domain.

373903:HORE RS12195
gene id: 373903:HORE_RS12195
uniprot id: B8D1E8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

373903:HORE RS04195
gene id: 373903:HORE_RS04195
uniprot id: B8CW85
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

373903:HORE RS05265
gene id: 373903:HORE_RS05265
uniprot id: B8CWT9
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

373903:HORE RS04030
gene id: 373903:HORE_RS04030
uniprot id: B8CW52
names: Function
names: Similarity
messages: Belongs to the CheD family.
messages: Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.

373903:HORE RS04760
gene id: 373903:HORE_RS04760
uniprot id: B8CWJ0
names: Similarity
messages: Belongs to the transpeptidase family.

373903:HORE RS00540
gene id: 373903:HORE_RS00540
uniprot id: B8D094
names: Similarity
messages: Belongs to the ClpA/ClpB family.

373903:HORE RS05445
gene id: 373903:HORE_RS05445
uniprot id: B8CWX4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

373903:HORE RS05200
gene id: 373903:HORE_RS05200
uniprot id: B8CWS6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

373903:HORE RS06380
gene id: 373903:HORE_RS06380
uniprot id: B8CXF2
names: Similarity
messages: Belongs to the RecJ family.

373903:HORE RS12090
gene id: 373903:HORE_RS12090
uniprot id: B8D1C7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

373903:HORE RS04560
gene id: 373903:HORE_RS04560
uniprot id: B8CWF7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

373903:HORE RS06505
gene id: 373903:HORE_RS06505
uniprot id: B8CXH5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

373903:HORE RS04855
gene id: 373903:HORE_RS04855
uniprot id: B8CWK9
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

373903:HORE RS03090
gene id: 373903:HORE_RS03090
uniprot id: B8D2B0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF nuclease family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

373903:HORE RS04880
gene id: 373903:HORE_RS04880
uniprot id: B8CWL4
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

373903:HORE RS05685
gene id: 373903:HORE_RS05685
uniprot id: B8CX21
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homotetramer.

373903:HORE RS03875
gene id: 373903:HORE_RS03875
uniprot id: B8CW21
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

373903:HORE RS00460
gene id: 373903:HORE_RS00460
uniprot id: B8D082
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

373903:HORE RS04775
gene id: 373903:HORE_RS04775
uniprot id: B8CWJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell inner membrane
messages: Membrane

373903:HORE RS08700
gene id: 373903:HORE_RS08700
uniprot id: B8CYQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

373903:HORE RS00525
gene id: 373903:HORE_RS00525
uniprot id: B8D091
names: Similarity
messages: Belongs to the CtsR family.

373903:HORE RS06200
gene id: 373903:HORE_RS06200
uniprot id: B8CXB9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

373903:HORE RS03035
gene id: 373903:HORE_RS03035
uniprot id: B8D299
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cell membrane
messages: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.
messages: Membrane

373903:HORE RS00830
gene id: 373903:HORE_RS00830
uniprot id: B8D0T6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

373903:HORE RS11735
gene id: 373903:HORE_RS11735
uniprot id: B8D0S4
names: Function
names: Similarity
messages: Belongs to the APS kinase family.
messages: Catalyzes the synthesis of activated sulfate.

373903:HORE RS10140
gene id: 373903:HORE_RS10140
uniprot id: B8CZI7
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.

373903:HORE RS03495
gene id: 373903:HORE_RS03495
uniprot id: B8D2I6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

373903:HORE RS06690
gene id: 373903:HORE_RS06690
uniprot id: B8CXL3
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

373903:HORE RS06565
gene id: 373903:HORE_RS06565
uniprot id: B8CXI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Membrane

373903:HORE RS05155
gene id: 373903:HORE_RS05155
uniprot id: B8CWR8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

373903:HORE RS07385
gene id: 373903:HORE_RS07385
uniprot id: B8CXZ7
names: Subcellular Location Annotation
messages: Membrane

373903:HORE RS07430
gene id: 373903:HORE_RS07430
uniprot id: B8CY06
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

373903:HORE RS06350
gene id: 373903:HORE_RS06350
uniprot id: B8CXE6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

373903:HORE RS00620
gene id: 373903:HORE_RS00620
uniprot id: B8D0B0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell inner membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

373903:HORE RS03095
gene id: 373903:HORE_RS03095
uniprot id: B8D2B1
names: Similarity
messages: Belongs to the UPF0473 family.

373903:HORE RS08415
gene id: 373903:HORE_RS08415
uniprot id: B8CYJ4
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by fructose 1,6-bisphosphate (FBP).
messages: Belongs to the LDH/MDH superfamily. LDH family.
messages: Catalyzes the conversion of lactate to pyruvate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

373903:HORE RS10570
gene id: 373903:HORE_RS10570
uniprot id: B8CZT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

373903:HORE RS03440
gene id: 373903:HORE_RS03440
uniprot id: B8D2H6
names: Cofactor
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.

373903:HORE RS06015
gene id: 373903:HORE_RS06015
uniprot id: B8CX81
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.

373903:HORE RS11880
gene id: 373903:HORE_RS11880
uniprot id: B8D186
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

373903:HORE RS06280
gene id: 373903:HORE_RS06280
uniprot id: B8CW01
names: Similarity
messages: Belongs to the UPF0236 family.

373903:HORE RS05525
gene id: 373903:HORE_RS05525
uniprot id: B8CWY9
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

373903:HORE RS09980
gene id: 373903:HORE_RS09980
uniprot id: B8CZF4
names: Similarity
messages: Belongs to the peptidase S8 family.

373903:HORE RS09655
gene id: 373903:HORE_RS09655
uniprot id: B8CZ92
names: Similarity
messages: Belongs to the bacterial secretin family.

373903:HORE RS03350
gene id: 373903:HORE_RS03350
uniprot id: B8D2G2
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

373903:HORE RS02550
gene id: 373903:HORE_RS02550
uniprot id: B8D212
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

373903:HORE RS08335
gene id: 373903:HORE_RS08335
uniprot id: B8CYH8
names: Similarity
messages: Belongs to the phosphohexose mutase family.

373903:HORE RS11625
gene id: 373903:HORE_RS11625
uniprot id: B8D0Q3
names: Similarity
messages: Belongs to the glycosyl hydrolase 32 family.

373903:HORE RS11455
gene id: 373903:HORE_RS11455
uniprot id: B8D0M0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

373903:HORE RS09250
gene id: 373903:HORE_RS09250
uniprot id: B8CZ09
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

373903:HORE RS08470
gene id: 373903:HORE_RS08470
uniprot id: B8CYK5
names: Similarity
messages: Belongs to the peptidase C40 family.

373903:HORE RS10175
gene id: 373903:HORE_RS10175
uniprot id: B8CZJ4
names: Subcellular Location Annotation
messages: Membrane

373903:HORE RS03165
gene id: 373903:HORE_RS03165
uniprot id: B8D2C5
names: Similarity
messages: Belongs to the EamA transporter family.

373903:HORE RS03860
gene id: 373903:HORE_RS03860
uniprot id: B8CW18
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

373903:HORE RS03500
gene id: 373903:HORE_RS03500
uniprot id: B8D2I7
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

373903:HORE RS07670
gene id: 373903:HORE_RS07670
uniprot id: B8CY54
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

373903:HORE RS11965
gene id: 373903:HORE_RS11965
uniprot id: B8D1A2
names: Similarity
messages: Belongs to the GARS family.

373903:HORE RS08955
gene id: 373903:HORE_RS08955
uniprot id: B8CYV2
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

373903:HORE RS01530
gene id: 373903:HORE_RS01530
uniprot id: B8D1G7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

373903:HORE RS00765
gene id: 373903:HORE_RS00765
uniprot id: B8D0D8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

373903:HORE RS10425
gene id: 373903:HORE_RS10425
uniprot id: B8CZQ9
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I. Phospho-HPr then transfers it to the PTS EIIA domain.

373903:HORE RS08930
gene id: 373903:HORE_RS08930
uniprot id: B8CYU6
names: Similarity
messages: Belongs to the FlgM family.

373903:HORE RS06325
gene id: 373903:HORE_RS06325
uniprot id: B8CXE1
names: Similarity
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit G family.

373903:HORE RS03665
gene id: 373903:HORE_RS03665
uniprot id: B8CVX8
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

373903:HORE RS07690
gene id: 373903:HORE_RS07690
uniprot id: B8CY58
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

373903:HORE RS05405
gene id: 373903:HORE_RS05405
uniprot id: B8CWW6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

373903:HORE RS11000
gene id: 373903:HORE_RS11000
uniprot id: B8D016
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

373903:HORE RS08210
gene id: 373903:HORE_RS08210
uniprot id: B8CYF2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

373903:HORE RS06370
gene id: 373903:HORE_RS06370
uniprot id: B8CXF0
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

373903:HORE RS08115
gene id: 373903:HORE_RS08115
uniprot id: B8CYD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

373903:HORE RS10645
gene id: 373903:HORE_RS10645
uniprot id: B8CZV2
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

373903:HORE RS09035
gene id: 373903:HORE_RS09035
uniprot id: B8CYW7
names: Similarity
messages: Belongs to the UDPGP type 2 family.

373903:HORE RS00425
gene id: 373903:HORE_RS00425
uniprot id: B8D075
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

373903:HORE RS00750
gene id: 373903:HORE_RS00750
uniprot id: B8D0D5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

373903:HORE RS11565
gene id: 373903:HORE_RS11565
uniprot id: B8D0P1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. DIT1 subfamily.
messages: Membrane

373903:HORE RS03580
gene id: 373903:HORE_RS03580
uniprot id: B8CVW1
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

373903:HORE RS10770
gene id: 373903:HORE_RS10770
uniprot id: B8CZX5
names: Cofactor
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.
messages: Binds 3 [4Fe-4S] clusters per subunit.

373903:HORE RS03555
gene id: 373903:HORE_RS03555
uniprot id: B8D2J8
names: Similarity
messages: Belongs to the carbamate kinase family.

373903:HORE RS04730
gene id: 373903:HORE_RS04730
uniprot id: B8CWI4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

373903:HORE RS08430
gene id: 373903:HORE_RS08430
uniprot id: B8CYJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

373903:HORE RS03235
gene id: 373903:HORE_RS03235
uniprot id: B8D2D9
names: Similarity
messages: Belongs to the bacterial secretin family.

373903:HORE RS06435
gene id: 373903:HORE_RS06435
uniprot id: B8CXG3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

373903:HORE RS06210
gene id: 373903:HORE_RS06210
uniprot id: B8CXC1
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

373903:HORE RS10435
gene id: 373903:HORE_RS10435
uniprot id: B8CZR1
names: Subcellular Location Annotation
messages: Membrane

373903:HORE RS04035
gene id: 373903:HORE_RS04035
uniprot id: B8CW53
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

373903:HORE RS00380
gene id: 373903:HORE_RS00380
uniprot id: B8D066
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

373903:HORE RS06760
gene id: 373903:HORE_RS06760
uniprot id: B8CXM7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Belongs to the peroxiredoxin family. Prx6 subfamily.
messages: Cytoplasm
messages: Homodecamer. Pentamer of dimers that assemble into a ring structure.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. Although the primary sequence of this enzyme is similar to those of the 1-Cys Prx6 enzymes, its catalytic properties resemble those of the typical 2-Cys Prxs and C(R) is provided by the other dimeric subunit to form an intersubunit disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

373903:HORE RS03460
gene id: 373903:HORE_RS03460
uniprot id: B8D2I0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

373903:HORE RS07465
gene id: 373903:HORE_RS07465
uniprot id: B8CY13
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RnfG family.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

373903:HORE RS07260
gene id: 373903:HORE_RS07260
uniprot id: B8CXX3
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

373903:HORE RS05450
gene id: 373903:HORE_RS05450
uniprot id: B8CWX5
names: Similarity
messages: Belongs to the EamA transporter family.

373903:HORE RS08425
gene id: 373903:HORE_RS08425
uniprot id: B8CYJ6
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

373903:HORE RS00005
gene id: 373903:HORE_RS00005
uniprot id: B8CZN4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

373903:HORE RS07605
gene id: 373903:HORE_RS07605
uniprot id: B8CY41
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

373903:HORE RS00790
gene id: 373903:HORE_RS00790
uniprot id: B8D0S8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell inner membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

373903:HORE RS04795
gene id: 373903:HORE_RS04795
uniprot id: B8CWJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

373903:HORE RS02630
gene id: 373903:HORE_RS02630
uniprot id: B8D228
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

373903:HORE RS03255
gene id: 373903:HORE_RS03255
uniprot id: B8D2E3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

373903:HORE RS02440
gene id: 373903:HORE_RS02440
uniprot id: B8D1Z0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

373903:HORE RS00950
gene id: 373903:HORE_RS00950
uniprot id: B8D0V9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

373903:HORE RS06765
gene id: 373903:HORE_RS06765
uniprot id: B8CXM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uridine kinase family.
messages: Cytoplasm

373903:HORE RS09140
gene id: 373903:HORE_RS09140
uniprot id: B8CYY7
names: Function
names: Similarity
messages: Belongs to the LpxC family.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

373903:HORE RS04770
gene id: 373903:HORE_RS04770
uniprot id: B8CWJ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

373903:HORE RS07520
gene id: 373903:HORE_RS07520
uniprot id: B8CY24
names: Similarity
messages: Belongs to the UPF0237 family.

373903:HORE RS11460
gene id: 373903:HORE_RS11460
uniprot id: B8D0M1
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

373903:HORE RS10855
gene id: 373903:HORE_RS10855
uniprot id: B8CZZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

373903:HORE RS09355
gene id: 373903:HORE_RS09355
uniprot id: B8CZ31
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

373903:HORE RS11775
gene id: 373903:HORE_RS11775
uniprot id: B8D166
names: Similarity
messages: Belongs to the PGI/PMI family.

373903:HORE RS11140
gene id: 373903:HORE_RS11140
uniprot id: B8D0G0
names: Similarity
messages: Belongs to the ABC transporter superfamily.

373903:HORE RS04280
gene id: 373903:HORE_RS04280
uniprot id: B8CWA2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

373903:HORE RS11515
gene id: 373903:HORE_RS11515
uniprot id: B8D0N1
names: Subcellular Location Annotation
messages: Membrane

373903:HORE RS01080
gene id: 373903:HORE_RS01080
uniprot id: B8D0Y5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

373903:HORE RS07565
gene id: 373903:HORE_RS07565
uniprot id: B8CY33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

373903:HORE RS11080
gene id: 373903:HORE_RS11080
uniprot id: B8D0E8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.
messages: Ca(+)/H(+) antiporter that extrudes calcium in exchange for external protons.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

373903:HORE RS04420
gene id: 373903:HORE_RS04420
uniprot id: B8CWD0
names: Similarity
messages: Belongs to the acylphosphatase family.

373903:HORE RS00645
gene id: 373903:HORE_RS00645
uniprot id: B8D0B4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

373903:HORE RS00410
gene id: 373903:HORE_RS00410
uniprot id: B8D072
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Membrane

373903:HORE RS11290
gene id: 373903:HORE_RS11290
uniprot id: B8D0I9
names: Similarity
messages: Belongs to the phosphosulfolactate synthase family.

373903:HORE RS11600
gene id: 373903:HORE_RS11600
uniprot id: B8D0P8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

373903:HORE RS08890
gene id: 373903:HORE_RS08890
uniprot id: B8CYT8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

373903:HORE RS06685
gene id: 373903:HORE_RS06685
uniprot id: B8CXL2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

373903:HORE RS09455
gene id: 373903:HORE_RS09455
uniprot id: B8CZ51
names: Similarity
messages: Belongs to the glycosyltransferase 1 family.

373903:HORE RS06300
gene id: 373903:HORE_RS06300
uniprot id: B8CXD6
names: Subcellular Location Annotation
messages: Membrane

373903:HORE RS04915
gene id: 373903:HORE_RS04915
uniprot id: B8CW01
names: Similarity
messages: Belongs to the UPF0236 family.

373903:HORE RS11940
gene id: 373903:HORE_RS11940
uniprot id: B8D198
names: Similarity
messages: Belongs to the manganese catalase family.

373903:HORE RS03245
gene id: 373903:HORE_RS03245
uniprot id: B8D2E1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

373903:HORE RS09495
gene id: 373903:HORE_RS09495
uniprot id: B8CZ59
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HCP family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Binds 1 hybrid [4Fe-2O-2S] cluster.
messages: Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
messages: Cytoplasm

373903:HORE RS00560
gene id: 373903:HORE_RS00560
uniprot id: B8D098
names: Similarity
messages: Belongs to the ycf81 family.

373903:HORE RS11480
gene id: 373903:HORE_RS11480
uniprot id: B8D0M5
names: Similarity
messages: Belongs to the SAICAR synthetase family.

373903:HORE RS12035
gene id: 373903:HORE_RS12035
uniprot id: B8D1B6
names: Subcellular Location Annotation
messages: Membrane

373903:HORE RS07525
gene id: 373903:HORE_RS07525
uniprot id: B8CY25
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

373903:HORE RS07460
gene id: 373903:HORE_RS07460
uniprot id: B8CY12
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

373903:HORE RS06135
gene id: 373903:HORE_RS06135
uniprot id: B8CXA5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

373903:HORE RS01280
gene id: 373903:HORE_RS01280
uniprot id: B8D125
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

373903:HORE RS11690
gene id: 373903:HORE_RS11690
uniprot id: B8D0R5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

373903:HORE RS00730
gene id: 373903:HORE_RS00730
uniprot id: B8D0D1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

373903:HORE RS11120
gene id: 373903:HORE_RS11120
uniprot id: B8D0F6
names: Subcellular Location Annotation
messages: Membrane

373903:HORE RS08710
gene id: 373903:HORE_RS08710
uniprot id: B8CYQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliP/MopC/SpaP family.
messages: Cell membrane
messages: Membrane
messages: Plays a role in the flagellum-specific transport system.

373903:HORE RS08520
gene id: 373903:HORE_RS08520
uniprot id: B8CYL5
names: Similarity
messages: Belongs to the peptidase S41A family.

373903:HORE RS10985
gene id: 373903:HORE_RS10985
uniprot id: B8D013
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

373903:HORE RS04955
gene id: 373903:HORE_RS04955
uniprot id: B8CWM9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate.
messages: Cytoplasm

373903:HORE RS08250
gene id: 373903:HORE_RS08250
uniprot id: B8CYG1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

373903:HORE RS01350
gene id: 373903:HORE_RS01350
uniprot id: B8D0U4
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

373903:HORE RS02990
gene id: 373903:HORE_RS02990
uniprot id: B8D290
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

373903:HORE RS06610
gene id: 373903:HORE_RS06610
uniprot id: B8CXJ7
names: Similarity
messages: Belongs to the bacterial secretin family.

373903:HORE RS12175
gene id: 373903:HORE_RS12175
uniprot id: B8D1E4
names: Similarity
messages: Belongs to the ParB family.

373903:HORE RS09835
gene id: 373903:HORE_RS09835
uniprot id: B8CZC6
names: Function
names: Similarity
names: Subunit
messages: Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization.
messages: Belongs to the HutP family.
messages: Homohexamer.

373903:HORE RS00430
gene id: 373903:HORE_RS00430
uniprot id: B8D076
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

373903:HORE RS05430
gene id: 373903:HORE_RS05430
uniprot id: B8CWX1
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis.
messages: Cytoplasm

373903:HORE RS06915
gene id: 373903:HORE_RS06915
uniprot id: B8CXQ9
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

373903:HORE RS00720
gene id: 373903:HORE_RS00720
uniprot id: B8D0C9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity).

373903:HORE RS11450
gene id: 373903:HORE_RS11450
uniprot id: B8D0L9
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

373903:HORE RS10580
gene id: 373903:HORE_RS10580
uniprot id: B8CZU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 1 family.
messages: Cell membrane

373903:HORE RS01335
gene id: 373903:HORE_RS01335
uniprot id: B8D0U1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the energy-coupling factor EcfT family.
messages: Cell membrane
messages: Forms a stable energy-coupling factor (ECF) transporter complex composed of 2 membrane-embedded substrate-binding proteins (S component), 2 ATP-binding proteins (A component) and 2 transmembrane proteins (T component).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.

373903:HORE RS07395
gene id: 373903:HORE_RS07395
uniprot id: B8CXZ9
names: Function
names: Similarity
messages: ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.
messages: Belongs to the ParA family. MinD subfamily.

373903:HORE RS08725
gene id: 373903:HORE_RS08725
uniprot id: B8CYQ6
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Membrane

373903:HORE RS02085
gene id: 373903:HORE_RS02085
uniprot id: B8D1S2
names: Similarity
messages: Belongs to the HupF/HypC family.

373903:HORE RS07390
gene id: 373903:HORE_RS07390
uniprot id: B8CXZ8
names: Function
names: Similarity
messages: Belongs to the MinE family.
messages: Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.

373903:HORE RS08810
gene id: 373903:HORE_RS08810
uniprot id: B8CYS2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

373903:HORE RS03825
gene id: 373903:HORE_RS03825
uniprot id: B8CW11
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

373903:HORE RS06970
gene id: 373903:HORE_RS06970
uniprot id: B8CXS0
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

373903:HORE RS11675
gene id: 373903:HORE_RS11675
uniprot id: B8D0R2
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

373903:HORE RS06425
gene id: 373903:HORE_RS06425
uniprot id: B8CXG1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

373903:HORE RS09865
gene id: 373903:HORE_RS09865
uniprot id: B8CZD2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
messages: Homodimer.

373903:HORE RS05180
gene id: 373903:HORE_RS05180
uniprot id: B8CW01
names: Similarity
messages: Belongs to the UPF0236 family.

373903:HORE RS10790
gene id: 373903:HORE_RS10790
uniprot id: B8CZX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

373903:HORE RS07235
gene id: 373903:HORE_RS07235
uniprot id: B8CXW9
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

373903:HORE RS08735
gene id: 373903:HORE_RS08735
uniprot id: B8CYQ8
names: Similarity
messages: Belongs to the MotB family.

373903:HORE RS04040
gene id: 373903:HORE_RS04040
uniprot id: B8CW54
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

373903:HORE RS08130
gene id: 373903:HORE_RS08130
uniprot id: B8CYD7
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

373903:HORE RS08385
gene id: 373903:HORE_RS08385
uniprot id: B8CYI8
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

373903:HORE RS11465
gene id: 373903:HORE_RS11465
uniprot id: B8D0M2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

373903:HORE RS03545
gene id: 373903:HORE_RS03545
uniprot id: B8D2J6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

373903:HORE RS05260
gene id: 373903:HORE_RS05260
uniprot id: B8CWT8
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

373903:HORE RS09735
gene id: 373903:HORE_RS09735
uniprot id: B8CZA8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

373903:HORE RS08705
gene id: 373903:HORE_RS08705
uniprot id: B8CYQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

373903:HORE RS00090
gene id: 373903:HORE_RS00090
uniprot id: B8CZQ0
names: Subcellular Location Annotation
messages: Membrane

373903:HORE RS01790
gene id: 373903:HORE_RS01790
uniprot id: B8D1M0
names: Similarity
messages: Belongs to the UPF0045 family.

373903:HORE RS12105
gene id: 373903:HORE_RS12105
uniprot id: B8D1D0
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

373903:HORE RS04105
gene id: 373903:HORE_RS04105
uniprot id: B8CW67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Membrane

373903:HORE RS11890
gene id: 373903:HORE_RS11890
uniprot id: B8D188
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

373903:HORE RS06400
gene id: 373903:HORE_RS06400
uniprot id: B8CXF6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

373903:HORE RS10110
gene id: 373903:HORE_RS10110
uniprot id: B8CZI1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the xylose isomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.

373903:HORE RS08030
gene id: 373903:HORE_RS08030
uniprot id: B8CYB8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

373903:HORE RS04080
gene id: 373903:HORE_RS04080
uniprot id: B8CW62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

373903:HORE RS09460
gene id: 373903:HORE_RS09460
uniprot id: B8CZ52
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

373903:HORE RS12240
gene id: 373903:HORE_RS12240
uniprot id: B8D0Y0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell inner membrane

373903:HORE RS04815
gene id: 373903:HORE_RS04815
uniprot id: B8CWK1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase U4 family.
messages: Cell membrane
messages: Probable aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE/spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR.

373903:HORE RS06640
gene id: 373903:HORE_RS06640
uniprot id: B8CXK3
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

373903:HORE RS12075
gene id: 373903:HORE_RS12075
uniprot id: B8D1C4
names: Similarity
messages: Belongs to the peptidase S16 family.

373903:HORE RS09420
gene id: 373903:HORE_RS09420
uniprot id: B8CZ44
names: Similarity
messages: Belongs to the peptidase M18 family.

373903:HORE RS10995
gene id: 373903:HORE_RS10995
uniprot id: B8D015
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

373903:HORE RS05385
gene id: 373903:HORE_RS05385
uniprot id: B8CWW2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

373903:HORE RS06315
gene id: 373903:HORE_RS06315
uniprot id: B8CXD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit B family.
messages: Cell membrane
messages: Membrane

373903:HORE RS09710
gene id: 373903:HORE_RS09710
uniprot id: B8CZA3
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

373903:HORE RS01585
gene id: 373903:HORE_RS01585
uniprot id: B8D1H8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

373903:HORE RS01685
gene id: 373903:HORE_RS01685
uniprot id: B8D1J8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-C family. DnaE subfamily.
messages: Cytoplasm
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The alpha chain is the DNA polymerase.

373903:HORE RS05350
gene id: 373903:HORE_RS05350
uniprot id: B8CWV5
names: Similarity
messages: Belongs to the peptidase S16 family.

373903:HORE RS08760
gene id: 373903:HORE_RS08760
uniprot id: B8CYR3
names: Similarity
messages: Belongs to the FlgD family.

373903:HORE RS04330
gene id: 373903:HORE_RS04330
uniprot id: B8CWB2
names: Similarity
messages: Belongs to the UPF0178 family.

373903:HORE RS08640
gene id: 373903:HORE_RS08640
uniprot id: B8CYN9
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

373903:HORE RS02120
gene id: 373903:HORE_RS02120
uniprot id: B8D1S9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

373903:HORE RS01760
gene id: 373903:HORE_RS01760
uniprot id: B8D1L4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

373903:HORE RS06010
gene id: 373903:HORE_RS06010
uniprot id: B8CX80
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

373903:HORE RS08120
gene id: 373903:HORE_RS08120
uniprot id: B8CYD5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

373903:HORE RS01765
gene id: 373903:HORE_RS01765
uniprot id: B8D1L5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

373903:HORE RS10345
gene id: 373903:HORE_RS10345
uniprot id: B8CZM9
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

373903:HORE RS05415
gene id: 373903:HORE_RS05415
uniprot id: B8CWW8
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

373903:HORE RS05030
gene id: 373903:HORE_RS05030
uniprot id: B8CWP4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L-fucose isomerase family.
messages: Converts the aldose L-fucose into the corresponding ketose L-fuculose.
messages: Cytoplasm

373903:HORE RS12470
gene id: 373903:HORE_RS12470
uniprot id: B8CXS6
names: Subcellular Location Annotation
messages: Membrane

373903:HORE RS04975
gene id: 373903:HORE_RS04975
uniprot id: B8CWN3
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

373903:HORE RS07650
gene id: 373903:HORE_RS07650
uniprot id: B8CY51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

373903:HORE RS06450
gene id: 373903:HORE_RS06450
uniprot id: B8CXG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

373903:HORE RS12140
gene id: 373903:HORE_RS12140
uniprot id: B8D1D7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

373903:HORE RS01095
gene id: 373903:HORE_RS01095
uniprot id: B8D0Y8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

373903:HORE RS02285
gene id: 373903:HORE_RS02285
uniprot id: B8D1V9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

373903:HORE RS04385
gene id: 373903:HORE_RS04385
uniprot id: B8CWC3
names: Subcellular Location Annotation
messages: Membrane

373903:HORE RS02025
gene id: 373903:HORE_RS02025
uniprot id: B8D1R1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmB/CycW/HelB family.
messages: Membrane

373903:HORE RS05420
gene id: 373903:HORE_RS05420
uniprot id: B8CWW9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

373903:HORE RS00740
gene id: 373903:HORE_RS00740
uniprot id: B8D0D3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

373903:HORE RS10315
gene id: 373903:HORE_RS10315
uniprot id: B8CZM2
names: Similarity
messages: Belongs to the threonine aldolase family.

373903:HORE RS06950
gene id: 373903:HORE_RS06950
uniprot id: B8CXR6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

373903:HORE RS10810
gene id: 373903:HORE_RS10810
uniprot id: B8CZY3
names: Similarity
names: Subunit
messages: Belongs to the beta-eliminating lyase family.
messages: Homotetramer.

373903:HORE RS03670
gene id: 373903:HORE_RS03670
uniprot id: B8CVX9
names: Similarity
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.

373903:HORE RS07760
gene id: 373903:HORE_RS07760
uniprot id: B8CY72
names: Similarity
messages: Belongs to the peptidase S16 family.

373903:HORE RS01125
gene id: 373903:HORE_RS01125
uniprot id: B8D0Z4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

373903:HORE RS10050
gene id: 373903:HORE_RS10050
uniprot id: B8CZG9
names: Function
names: Similarity
messages: Belongs to the V-ATPase E subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

373903:HORE RS01340
gene id: 373903:HORE_RS01340
uniprot id: B8D0U2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

373903:HORE RS04520
gene id: 373903:HORE_RS04520
uniprot id: B8CWE9
names: Similarity
messages: Belongs to the EamA transporter family.

373903:HORE RS06825
gene id: 373903:HORE_RS06825
uniprot id: B8CXP1
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

373903:HORE RS05695
gene id: 373903:HORE_RS05695
uniprot id: B8CX23
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 2 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

373903:HORE RS07485
gene id: 373903:HORE_RS07485
uniprot id: B8CY17
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

373903:HORE RS03175
gene id: 373903:HORE_RS03175
uniprot id: B8D2C7
names: Similarity
messages: Belongs to the GSP E family.

373903:HORE RS03700
gene id: 373903:HORE_RS03700
uniprot id: B8CVY5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Catalyzes phosphorolysis of the pyrimidine nucleosides uridine, thymidine and 2'-deoxyuridine with the formation of the corresponding pyrimidine base and ribose-1-phosphate.
messages: Homodimer.

373903:HORE RS01165
gene id: 373903:HORE_RS01165
uniprot id: B8D102
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transcriptional regulatory Rex family.
messages: Cytoplasm
messages: Homodimer.
messages: Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.

373903:HORE RS03020
gene id: 373903:HORE_RS03020
uniprot id: B8D296
names: Subcellular Location Annotation
messages: Membrane

373903:HORE RS00960
gene id: 373903:HORE_RS00960
uniprot id: B8D0W1
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

373903:HORE RS06165
gene id: 373903:HORE_RS06165
uniprot id: B8CXB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

373903:HORE RS06530
gene id: 373903:HORE_RS06530
uniprot id: B8CXI1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

373903:HORE RS05585
gene id: 373903:HORE_RS05585
uniprot id: B8CX01
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane
messages: This protein catalyzes the committed step to the synthesis of the acidic phospholipids.

373903:HORE RS06980
gene id: 373903:HORE_RS06980
uniprot id: B8CXS2
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

373903:HORE RS01285
gene id: 373903:HORE_RS01285
uniprot id: B8D126
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

373903:HORE RS00630
gene id: 373903:HORE_RS00630
uniprot id: B8D0B2
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

373903:HORE RS08775
gene id: 373903:HORE_RS08775
uniprot id: B8CYR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliJ family.
messages: Cell membrane
messages: Membrane

373903:HORE RS00585
gene id: 373903:HORE_RS00585
uniprot id: B8D0A3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

373903:HORE RS04785
gene id: 373903:HORE_RS04785
uniprot id: B8CWJ5
names: Subcellular Location Annotation
messages: Membrane

373903:HORE RS08345
gene id: 373903:HORE_RS08345
uniprot id: B8CYI0
names: Similarity
messages: Belongs to the glycosyl hydrolase 57 family.

373903:HORE RS05455
gene id: 373903:HORE_RS05455
uniprot id: B8CWX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

373903:HORE RS06830
gene id: 373903:HORE_RS06830
uniprot id: B8CXP2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycosyl hydrolase 2 family.
messages: Homodimer.
messages: Secreted

373903:HORE RS09685
gene id: 373903:HORE_RS09685
uniprot id: B8CZ98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP G family.
messages: Cell inner membrane
messages: Membrane

373903:HORE RS09210
gene id: 373903:HORE_RS09210
uniprot id: B8CZ01
names: Subcellular Location Annotation
messages: Membrane

373903:HORE RS02885
gene id: 373903:HORE_RS02885
uniprot id: B8D276
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Membrane

373903:HORE RS01710
gene id: 373903:HORE_RS01710
uniprot id: B8D1K4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

373903:HORE RS08625
gene id: 373903:HORE_RS08625
uniprot id: B8CYN6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgH family.
messages: Cell outer membrane
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

373903:HORE RS00475
gene id: 373903:HORE_RS00475
uniprot id: B8D085
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 1 family.
messages: Cell membrane

373903:HORE RS07475
gene id: 373903:HORE_RS07475
uniprot id: B8CY15
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

373903:HORE RS08465
gene id: 373903:HORE_RS08465
uniprot id: B8CYK4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM61 family.
messages: Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA.
messages: Homotetramer composed of a dimer of dimers.

373903:HORE RS05535
gene id: 373903:HORE_RS05535
uniprot id: B8CWZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

373903:HORE RS05305
gene id: 373903:HORE_RS05305
uniprot id: B8CWU6
names: Similarity
messages: Belongs to the asp23 family.

373903:HORE RS01330
gene id: 373903:HORE_RS01330
uniprot id: B8D0U0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex.
messages: Belongs to the ABC transporter superfamily. Energy-coupling factor EcfA family.
messages: Cell membrane
messages: Forms a stable energy-coupling factor (ECF) transporter complex composed of 2 membrane-embedded substrate-binding proteins (S component), 2 ATP-binding proteins (A component) and 2 transmembrane proteins (T component).
messages: Membrane

373903:HORE RS10695
gene id: 373903:HORE_RS10695
uniprot id: B8CZW2
names: Function
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.
messages: Transcriptional repressor of xylose-utilizing enzymes.

373903:HORE RS01010
gene id: 373903:HORE_RS01010
uniprot id: B8D0X2
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

373903:HORE RS10270
gene id: 373903:HORE_RS10270
uniprot id: B8CZL3
names: Subcellular Location Annotation
messages: Membrane

373903:HORE RS03195
gene id: 373903:HORE_RS03195
uniprot id: B8D2D1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Membrane

373903:HORE RS04635
gene id: 373903:HORE_RS04635
uniprot id: B8CWH0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

373903:HORE RS08800
gene id: 373903:HORE_RS08800
uniprot id: B8CYS0
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

373903:HORE RS00670
gene id: 373903:HORE_RS00670
uniprot id: B8D0B9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

373903:HORE RS02080
gene id: 373903:HORE_RS02080
uniprot id: B8D1S1
names: Similarity
messages: Belongs to the acylphosphatase family.
messages: Belongs to the carbamoyltransferase HypF family.

373903:HORE RS00365
gene id: 373903:HORE_RS00365
uniprot id: B8D063
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

373903:HORE RS03140
gene id: 373903:HORE_RS03140
uniprot id: B8D2C0
names: Similarity
messages: Belongs to the Fur family.

373903:HORE RS08485
gene id: 373903:HORE_RS08485
uniprot id: B8CYK8
names: Similarity
messages: Belongs to the 6-phosphogluconate dehydrogenase family.

373903:HORE RS05400
gene id: 373903:HORE_RS05400
uniprot id: B8CWW5
names: Similarity
messages: Belongs to the fabD family.

373903:HORE RS06335
gene id: 373903:HORE_RS06335
uniprot id: B8CXE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

373903:HORE RS03485
gene id: 373903:HORE_RS03485
uniprot id: B8D2I4
names: Similarity
messages: Belongs to the TlyA family.

373903:HORE RS10740
gene id: 373903:HORE_RS10740
uniprot id: B8CZX1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

373903:HORE RS07915
gene id: 373903:HORE_RS07915
uniprot id: B8CY99
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated exonuclease Cas4 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).
messages: Mg(2+) or Mn(2+) required for ssDNA cleavage activity.

373903:HORE RS04115
gene id: 373903:HORE_RS04115
uniprot id: B8CW69
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

373903:HORE RS04810
gene id: 373903:HORE_RS04810
uniprot id: B8CWK0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

373903:HORE RS07515
gene id: 373903:HORE_RS07515
uniprot id: B8CY23
names: Similarity
names: Subunit
messages: Belongs to the UPF0210 family.
messages: Homodimer.

373903:HORE RS00455
gene id: 373903:HORE_RS00455
uniprot id: B8D081
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

373903:HORE RS06900
gene id: 373903:HORE_RS06900
uniprot id: B8CXQ6
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.

373903:HORE RS05630
gene id: 373903:HORE_RS05630
uniprot id: B8CX10
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

373903:HORE RS01090
gene id: 373903:HORE_RS01090
uniprot id: B8D0Y7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

373903:HORE RS00590
gene id: 373903:HORE_RS00590
uniprot id: B8D0A4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MrnC RNase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc); Rnc processes 30S rRNA into smaller rRNA precursors.

373903:HORE RS00795
gene id: 373903:HORE_RS00795
uniprot id: B8D0S9
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

373903:HORE RS00715
gene id: 373903:HORE_RS00715
uniprot id: B8D0C8
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

373903:HORE RS08915
gene id: 373903:HORE_RS08915
uniprot id: B8CYU3
names: Similarity
messages: Belongs to the bacterial flagellin family.

373903:HORE RS00550
gene id: 373903:HORE_RS00550
uniprot id: B8D096
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DisA family.
messages: Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation; upon encountering a lesion, the DisA focus arrests at the damaged site and halts c-di-AMP synthesis.
messages: Homooctamer.
messages: Participates in a DNA-damage check-point that is active prior to asymmetric division when DNA is damaged. DisA forms globular foci that rapidly scan along the chromosomes during sporulation, searching for lesions. When a lesion is present, DisA pauses at the lesion site. This triggers a cellular response that culminates in a temporary block in sporulation initiation.

373903:HORE RS12185
gene id: 373903:HORE_RS12185
uniprot id: B8D1E6
names: Similarity
messages: Belongs to the ParB family.

373903:HORE RS05565
gene id: 373903:HORE_RS05565
uniprot id: B8CWZ7
names: Subcellular Location Annotation
messages: Membrane

373903:HORE RS05480
gene id: 373903:HORE_RS05480
uniprot id: B8CWY1
names: Similarity
messages: Belongs to the hemerythrin family.

373903:HORE RS08620
gene id: 373903:HORE_RS08620
uniprot id: B8CYN5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgI family.
messages: Periplasm
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

373903:HORE RS07510
gene id: 373903:HORE_RS07510
uniprot id: B8CY22
names: Similarity
messages: Belongs to the glycosyl hydrolase 38 family.

373903:HORE RS06285
gene id: 373903:HORE_RS06285
uniprot id: B8CXD3
names: Similarity
messages: Belongs to the IMPACT family.

373903:HORE RS11990
gene id: 373903:HORE_RS11990
uniprot id: B8D1A7
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.

373903:HORE RS08390
gene id: 373903:HORE_RS08390
uniprot id: B8CYI9
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

373903:HORE RS03040
gene id: 373903:HORE_RS03040
uniprot id: B8D2A0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

373903:HORE RS03785
gene id: 373903:HORE_RS03785
uniprot id: B8CW03
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

373903:HORE RS03620
gene id: 373903:HORE_RS03620
uniprot id: B8CVW9
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

373903:HORE RS06065
gene id: 373903:HORE_RS06065
uniprot id: B8CX91
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

373903:HORE RS05555
gene id: 373903:HORE_RS05555
uniprot id: B8CWZ5
names: Similarity
messages: Belongs to the OsmC/Ohr family.

373903:HORE RS03775
gene id: 373903:HORE_RS03775
uniprot id: B8CW01
names: Similarity
messages: Belongs to the UPF0236 family.

373903:HORE RS07755
gene id: 373903:HORE_RS07755
uniprot id: B8CY71
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

373903:HORE RS12055
gene id: 373903:HORE_RS12055
uniprot id: B8D1C0
names: Subcellular Location Annotation
messages: Membrane

373903:HORE RS09300
gene id: 373903:HORE_RS09300
uniprot id: B8CZ20
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

373903:HORE RS10895
gene id: 373903:HORE_RS10895
uniprot id: B8CZZ9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.

373903:HORE RS01705
gene id: 373903:HORE_RS01705
uniprot id: B8D1K3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

373903:HORE RS12100
gene id: 373903:HORE_RS12100
uniprot id: B8D1C9
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

373903:HORE RS07410
gene id: 373903:HORE_RS07410
uniprot id: B8CY02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Membrane

373903:HORE RS09280
gene id: 373903:HORE_RS09280
uniprot id: B8CZ16
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase C chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

373903:HORE RS06125
gene id: 373903:HORE_RS06125
uniprot id: B8CXA2
names: Subcellular Location Annotation
messages: Membrane

373903:HORE RS09260
gene id: 373903:HORE_RS09260
uniprot id: B8CZ11
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

373903:HORE RS11560
gene id: 373903:HORE_RS11560
uniprot id: B8D0P0
names: Subcellular Location Annotation
messages: Membrane

373903:HORE RS04550
gene id: 373903:HORE_RS04550
uniprot id: B8CWF5
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids threonine, isoleucine and methionine.

373903:HORE RS00810
gene id: 373903:HORE_RS00810
uniprot id: B8D0T2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

373903:HORE RS06740
gene id: 373903:HORE_RS06740
uniprot id: B8CXM3
names: Subcellular Location Annotation
messages: Membrane

373903:HORE RS00755
gene id: 373903:HORE_RS00755
uniprot id: B8D0D6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

373903:HORE RS08990
gene id: 373903:HORE_RS08990
uniprot id: B8CYV8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell inner membrane
messages: Probably interacts with PlsX.

373903:HORE RS04725
gene id: 373903:HORE_RS04725
uniprot id: B8CWI3
names: Similarity
messages: Belongs to the Fur family.

373903:HORE RS05390
gene id: 373903:HORE_RS05390
uniprot id: B8CWW3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

373903:HORE RS10650
gene id: 373903:HORE_RS10650
uniprot id: B8CZV3
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

373903:HORE RS01625
gene id: 373903:HORE_RS01625
uniprot id: B8D1I6
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

373903:HORE RS10470
gene id: 373903:HORE_RS10470
uniprot id: B8CZR8
names: Subcellular Location Annotation
messages: Membrane

373903:HORE RS04335
gene id: 373903:HORE_RS04335
uniprot id: B8CWB3
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

373903:HORE RS12050
gene id: 373903:HORE_RS12050
uniprot id: B8D1B9
names: Subcellular Location Annotation
messages: Membrane

373903:HORE RS02880
gene id: 373903:HORE_RS02880
uniprot id: B8D275
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

373903:HORE RS04970
gene id: 373903:HORE_RS04970
uniprot id: B8CWN2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

373903:HORE RS08635
gene id: 373903:HORE_RS08635
uniprot id: B8CYN8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

373903:HORE RS03715
gene id: 373903:HORE_RS03715
uniprot id: B8CVY8
names: Function
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.
messages: In the phosphorylated form it could act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma f from inhibition.

373903:HORE RS11530
gene id: 373903:HORE_RS11530
uniprot id: B8D0N4
names: Subcellular Location Annotation
messages: Membrane

373903:HORE RS07350
gene id: 373903:HORE_RS07350
uniprot id: B8CXZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

373903:HORE RS06440
gene id: 373903:HORE_RS06440
uniprot id: B8CXG4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RuvC family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.

373903:HORE RS08460
gene id: 373903:HORE_RS08460
uniprot id: B8CYK3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

373903:HORE RS05925
gene id: 373903:HORE_RS05925
uniprot id: B8CX64
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

373903:HORE RS06540
gene id: 373903:HORE_RS06540
uniprot id: B8CXI3
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

373903:HORE RS01085
gene id: 373903:HORE_RS01085
uniprot id: B8D0Y6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

373903:HORE RS06410
gene id: 373903:HORE_RS06410
uniprot id: B8CXF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Cell membrane
messages: Membrane

373903:HORE RS10100
gene id: 373903:HORE_RS10100
uniprot id: B8CZH9
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Catalyzes the phosphorylation of D-xylulose to D-xylulose 5-phosphate.

373903:HORE RS04580
gene id: 373903:HORE_RS04580
uniprot id: B8CWG2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell inner membrane

373903:HORE RS04425
gene id: 373903:HORE_RS04425
uniprot id: B8CW01
names: Similarity
messages: Belongs to the UPF0236 family.

373903:HORE RS02545
gene id: 373903:HORE_RS02545
uniprot id: B8D211
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

373903:HORE RS00820
gene id: 373903:HORE_RS00820
uniprot id: B8D0T4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

373903:HORE RS09555
gene id: 373903:HORE_RS09555
uniprot id: B8CZ71
names: Subcellular Location Annotation
messages: Membrane

373903:HORE RS05285
gene id: 373903:HORE_RS05285
uniprot id: B8CWU2
names: Similarity
messages: Belongs to the class-I fumarase family.

373903:HORE RS03170
gene id: 373903:HORE_RS03170
uniprot id: B8D2C6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).

373903:HORE RS01485
gene id: 373903:HORE_RS01485
uniprot id: B8D1F8
names: Similarity
messages: Belongs to the OsmC/Ohr family.

373903:HORE RS08230
gene id: 373903:HORE_RS08230
uniprot id: B8CYF6
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-stimulated subfamily.
messages: Cell inner membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Requires K(+) for maximal activity.
messages: Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na(+) movement across the membrane.

373903:HORE RS06700
gene id: 373903:HORE_RS06700
uniprot id: B8CXL5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell inner membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

373903:HORE RS06105
gene id: 373903:HORE_RS06105
uniprot id: B8CX98
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

373903:HORE RS05165
gene id: 373903:HORE_RS05165
uniprot id: B8CWS0
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

373903:HORE RS05225
gene id: 373903:HORE_RS05225
uniprot id: B8CWT1
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

373903:HORE RS03105
gene id: 373903:HORE_RS03105
uniprot id: B8D2B3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family.
messages: Catalyzes the methylation of 5-hydroxyuridine (ho5U) to form 5-methoxyuridine (mo5U) at position 34 in tRNAs.
messages: Homodimer.

373903:HORE RS04165
gene id: 373903:HORE_RS04165
uniprot id: B8CW79
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AP endonuclease 2 family.
messages: Binds 3 Zn(2+) ions.
messages: Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.

373903:HORE RS11740
gene id: 373903:HORE_RS11740
uniprot id: B8D0S5
names: Similarity
messages: Belongs to the sulfate adenylyltransferase family.

373903:HORE RS11310
gene id: 373903:HORE_RS11310
uniprot id: B8D0J3
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT.

373903:HORE RS06535
gene id: 373903:HORE_RS06535
uniprot id: B8CXI2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell inner membrane
messages: Cytoplasm
messages: Monomer.

373903:HORE RS06840
gene id: 373903:HORE_RS06840
uniprot id: B8CXP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

373903:HORE RS05245
gene id: 373903:HORE_RS05245
uniprot id: B8CWT5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

373903:HORE RS06495
gene id: 373903:HORE_RS06495
uniprot id: B8CXH3
names: Similarity
messages: Belongs to the dGTPase family. Type 2 subfamily.

373903:HORE RS03985
gene id: 373903:HORE_RS03985
uniprot id: B8CW43
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmG family. TrmFO subfamily.
messages: Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
messages: Cytoplasm

373903:HORE RS11865
gene id: 373903:HORE_RS11865
uniprot id: B8D183
names: Subcellular Location Annotation
messages: Membrane

373903:HORE RS06045
gene id: 373903:HORE_RS06045
uniprot id: B8CX87
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

373903:HORE RS01210
gene id: 373903:HORE_RS01210
uniprot id: B8D111
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Lacks the C-terminal regulatory region which is replaced by HisZ.

373903:HORE RS04735
gene id: 373903:HORE_RS04735
uniprot id: B8CWI5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

373903:HORE RS03260
gene id: 373903:HORE_RS03260
uniprot id: B8D2E4
names: Similarity
messages: Belongs to the peptidase M24B family.

373903:HORE RS07765
gene id: 373903:HORE_RS07765
uniprot id: B8CY73
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

373903:HORE RS07775
gene id: 373903:HORE_RS07775
uniprot id: B8CY75
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

373903:HORE RS09180
gene id: 373903:HORE_RS09180
uniprot id: B8CYZ5
names: Similarity
messages: Belongs to the Skp family.

373903:HORE RS01405
gene id: 373903:HORE_RS01405
uniprot id: B8D149
names: Subcellular Location Annotation
messages: Membrane

373903:HORE RS03315
gene id: 373903:HORE_RS03315
uniprot id: B8D2F5
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

373903:HORE RS02445
gene id: 373903:HORE_RS02445
uniprot id: B8D1Z1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

373903:HORE RS05465
gene id: 373903:HORE_RS05465
uniprot id: B8CWX8
names: Subcellular Location Annotation
messages: Membrane

373903:HORE RS00175
gene id: 373903:HORE_RS00175
uniprot id: B8D027
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

373903:HORE RS04145
gene id: 373903:HORE_RS04145
uniprot id: B8CW75
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

373903:HORE RS02170
gene id: 373903:HORE_RS02170
uniprot id: B8D1T7
names: Subcellular Location Annotation
messages: Membrane

373903:HORE RS03250
gene id: 373903:HORE_RS03250
uniprot id: B8D2E2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

373903:HORE RS00855
gene id: 373903:HORE_RS00855
uniprot id: B8D0U1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the energy-coupling factor EcfT family.
messages: Cell membrane
messages: Forms a stable energy-coupling factor (ECF) transporter complex composed of 2 membrane-embedded substrate-binding proteins (S component), 2 ATP-binding proteins (A component) and 2 transmembrane proteins (T component).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.

373903:HORE RS07550
gene id: 373903:HORE_RS07550
uniprot id: B8CY30
names: Similarity
messages: Belongs to the EamA transporter family.

373903:HORE RS05065
gene id: 373903:HORE_RS05065
uniprot id: B8CWQ0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M20B family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Cleaves the N-terminal amino acid of tripeptides.
messages: Cytoplasm

373903:HORE RS03685
gene id: 373903:HORE_RS03685
uniprot id: B8CVY2
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

373903:HORE RS11870
gene id: 373903:HORE_RS11870
uniprot id: B8D184
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

373903:HORE RS01220
gene id: 373903:HORE_RS01220
uniprot id: B8D113
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

373903:HORE RS03010
gene id: 373903:HORE_RS03010
uniprot id: B8D294
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

373903:HORE RS10745
gene id: 373903:HORE_RS10745
uniprot id: B8CZX2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

373903:HORE RS00910
gene id: 373903:HORE_RS00910
uniprot id: B8D0V1
names: Cofactor
names: Similarity
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.
messages: Binds 1 zinc ion per subunit.

373903:HORE RS06670
gene id: 373903:HORE_RS06670
uniprot id: B8CXK9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

373903:HORE RS05195
gene id: 373903:HORE_RS05195
uniprot id: B8CWS5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

373903:HORE RS11610
gene id: 373903:HORE_RS11610
uniprot id: B8D0Q0
names: Similarity
messages: Belongs to the asparagine synthetase family.

373903:HORE RS00770
gene id: 373903:HORE_RS00770
uniprot id: B8D0D9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

373903:HORE RS08245
gene id: 373903:HORE_RS08245
uniprot id: B8CYG0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

373903:HORE RS11445
gene id: 373903:HORE_RS11445
uniprot id: B8D0L8
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

373903:HORE RS05610
gene id: 373903:HORE_RS05610
uniprot id: B8CX07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0182 family.
messages: Cell membrane

373903:HORE RS10490
gene id: 373903:HORE_RS10490
uniprot id: B8CZS2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transcriptional regulatory Rex family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.

373903:HORE RS12320
gene id: 373903:HORE_RS12320
uniprot id: B8D235
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

373903:HORE RS01225
gene id: 373903:HORE_RS01225
uniprot id: B8D114
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

373903:HORE RS05190
gene id: 373903:HORE_RS05190
uniprot id: B8CWS4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LPG synthase family.
messages: Catalyzes the transfer of a lysyl group from L-lysyl-tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms.
messages: Cell membrane
messages: Membrane

373903:HORE RS11960
gene id: 373903:HORE_RS11960
uniprot id: B8D1A1
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

373903:HORE RS11500
gene id: 373903:HORE_RS11500
uniprot id: B8D0M8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

373903:HORE RS10190
gene id: 373903:HORE_RS10190
uniprot id: B8CZJ7
names: Subcellular Location Annotation
messages: Cell membrane

373903:HORE RS07710
gene id: 373903:HORE_RS07710
uniprot id: B8CY62
names: Similarity
messages: Belongs to the UbiD family.

373903:HORE RS08365
gene id: 373903:HORE_RS08365
uniprot id: B8CYI4
names: Caution
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HPrK/P family.
messages: Both phosphorylation and phosphorolysis are carried out by the same active site and suggest a common mechanism for both reactions.
messages: Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK/P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport: it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion.
messages: Homohexamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The Walker A ATP-binding motif also binds Pi and PPi.

373903:HORE RS06225
gene id: 373903:HORE_RS06225
uniprot id: B8CXC4
names: Similarity
messages: Belongs to the AAA ATPase family.
messages: In the C-terminal section; belongs to the peptidase M41 family.

373903:HORE RS11180
gene id: 373903:HORE_RS11180
uniprot id: B8D0G8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

373903:HORE RS03595
gene id: 373903:HORE_RS03595
uniprot id: B8CVW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetokinase family.
messages: Cytoplasm

373903:HORE RS10630
gene id: 373903:HORE_RS10630
uniprot id: B8CZV0
names: Similarity
messages: Belongs to the peptidase S33 family.

373903:HORE RS08035
gene id: 373903:HORE_RS08035
uniprot id: B8CYB9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

373903:HORE RS07845
gene id: 373903:HORE_RS07845
uniprot id: B8CY87
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

373903:HORE RS05375
gene id: 373903:HORE_RS05375
uniprot id: B8CWW0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

373903:HORE RS06195
gene id: 373903:HORE_RS06195
uniprot id: B8CXB8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase Y family.
messages: Cell membrane
messages: Endoribonuclease that initiates mRNA decay.

373903:HORE RS01315
gene id: 373903:HORE_RS01315
uniprot id: B8D132
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

373903:HORE RS05355
gene id: 373903:HORE_RS05355
uniprot id: B8CWV6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TmcAL family.
messages: Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates. First activates an acetate ion to form acetyladenylate (Ac-AMP) and then transfers the acetyl group to tRNA to form ac(4)C34.
messages: Cytoplasm

373903:HORE RS00605
gene id: 373903:HORE_RS00605
uniprot id: B8D0A7
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. Sigma-S contributes to the protection against external stress, thus playing a role in cellular fitness and survival.

373903:HORE RS08865
gene id: 373903:HORE_RS08865
uniprot id: B8CYT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

373903:HORE RS00725
gene id: 373903:HORE_RS00725
uniprot id: B8D0D0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

373903:HORE RS00700
gene id: 373903:HORE_RS00700
uniprot id: B8D0C5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

373903:HORE RS12250
gene id: 373903:HORE_RS12250
uniprot id: B8D1L9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

373903:HORE RS04130
gene id: 373903:HORE_RS04130
uniprot id: B8CW72
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

373903:HORE RS06490
gene id: 373903:HORE_RS06490
uniprot id: B8CXH2
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

373903:HORE RS10780
gene id: 373903:HORE_RS10780
uniprot id: B8CZX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

373903:HORE RS01230
gene id: 373903:HORE_RS01230
uniprot id: B8D115
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

373903:HORE RS05220
gene id: 373903:HORE_RS05220
uniprot id: B8CWT0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Cytoplasm
messages: Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.

373903:HORE RS03450
gene id: 373903:HORE_RS03450
uniprot id: B8D2H8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

373903:HORE RS06035
gene id: 373903:HORE_RS06035
uniprot id: B8CX85
names: Similarity
messages: Belongs to the PHP hydrolase family. HisK subfamily.

373903:HORE RS10480
gene id: 373903:HORE_RS10480
uniprot id: B8CZS0
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

373903:HORE RS08515
gene id: 373903:HORE_RS08515
uniprot id: B8CYL4
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

373903:HORE RS03695
gene id: 373903:HORE_RS03695
uniprot id: B8CVY4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: Homotrimer.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.

373903:HORE RS07530
gene id: 373903:HORE_RS07530
uniprot id: B8CY26
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
messages: Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.
messages: Cytoplasm

373903:HORE RS09405
gene id: 373903:HORE_RS09405
uniprot id: B8CZ41
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

373903:HORE RS08105
gene id: 373903:HORE_RS08105
uniprot id: B8CYD2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

373903:HORE RS06865
gene id: 373903:HORE_RS06865
uniprot id: B8CXP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

373903:HORE RS03870
gene id: 373903:HORE_RS03870
uniprot id: B8CW20
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

373903:HORE RS04245
gene id: 373903:HORE_RS04245
uniprot id: B8CW95
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Cu-Zn superoxide dismutase family.
messages: Binds 1 copper ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

373903:HORE RS10500
gene id: 373903:HORE_RS10500
uniprot id: B8CZS4
names: Similarity
messages: Belongs to the iron-containing alcohol dehydrogenase family.

373903:HORE RS04930
gene id: 373903:HORE_RS04930
uniprot id: B8CWM4
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

373903:HORE RS08565
gene id: 373903:HORE_RS08565
uniprot id: B8CYM4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell inner membrane
messages: Cytoplasm
messages: May bind 1 zinc ion per subunit.
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

373903:HORE RS09690
gene id: 373903:HORE_RS09690
uniprot id: B8CZ99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

373903:HORE RS10820
gene id: 373903:HORE_RS10820
uniprot id: B8CZY5
names: Similarity
messages: Belongs to the RutC family.

373903:HORE RS04740
gene id: 373903:HORE_RS04740
uniprot id: B8CWI6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

373903:HORE RS01265
gene id: 373903:HORE_RS01265
uniprot id: B8D122
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

373903:HORE RS00955
gene id: 373903:HORE_RS00955
uniprot id: B8D0W0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

373903:HORE RS03855
gene id: 373903:HORE_RS03855
uniprot id: B8CW17
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

373903:HORE RS01370
gene id: 373903:HORE_RS01370
uniprot id: B8D0U7
names: Cofactor
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

373903:HORE RS10775
gene id: 373903:HORE_RS10775
uniprot id: B8CZX6
names: Similarity
messages: Belongs to the glycosyl hydrolase 65 family.

373903:HORE RS00705
gene id: 373903:HORE_RS00705
uniprot id: B8D0C6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

373903:HORE RS04840
gene id: 373903:HORE_RS04840
uniprot id: B8CWK6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

373903:HORE RS00890
gene id: 373903:HORE_RS00890
uniprot id: B8D0U7
names: Cofactor
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

373903:HORE RS06245
gene id: 373903:HORE_RS06245
uniprot id: B8CXC8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
messages: Cytoplasm

373903:HORE RS00545
gene id: 373903:HORE_RS00545
uniprot id: B8D095
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

373903:HORE RS00870
gene id: 373903:HORE_RS00870
uniprot id: B8D0U4
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

373903:HORE RS05650
gene id: 373903:HORE_RS05650
uniprot id: B8CX14
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

373903:HORE RS02580
gene id: 373903:HORE_RS02580
uniprot id: B8D218
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

373903:HORE RS01130
gene id: 373903:HORE_RS01130
uniprot id: B8D0Z5
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

373903:HORE RS08440
gene id: 373903:HORE_RS08440
uniprot id: B8CYJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 1 family.
messages: Cell membrane

373903:HORE RS07560
gene id: 373903:HORE_RS07560
uniprot id: B8CY32
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

373903:HORE RS06810
gene id: 373903:HORE_RS06810
uniprot id: B8CXN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

373903:HORE RS06925
gene id: 373903:HORE_RS06925
uniprot id: B8CXR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpxP/Spy family.
messages: Periplasm

373903:HORE RS06520
gene id: 373903:HORE_RS06520
uniprot id: B8CXH9
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

373903:HORE RS04585
gene id: 373903:HORE_RS04585
uniprot id: B8CWG3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Homohexamer. Forms a ring that surrounds DNA.
messages: Membrane

373903:HORE RS12125
gene id: 373903:HORE_RS12125
uniprot id: B8D1D4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. C-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

373903:HORE RS06040
gene id: 373903:HORE_RS06040
uniprot id: B8CX86
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

373903:HORE RS01460
gene id: 373903:HORE_RS01460
uniprot id: B8D161
names: Similarity
messages: Belongs to the DtxR/MntR family.

373903:HORE RS06140
gene id: 373903:HORE_RS06140
uniprot id: B8CXA6
names: Similarity
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.

373903:HORE RS01385
gene id: 373903:HORE_RS01385
uniprot id: B8D145
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

373903:HORE RS05365
gene id: 373903:HORE_RS05365
uniprot id: B8CWV8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

373903:HORE RS01075
gene id: 373903:HORE_RS01075
uniprot id: B8D0Y4
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

373903:HORE RS00395
gene id: 373903:HORE_RS00395
uniprot id: B8D069
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

373903:HORE RS12190
gene id: 373903:HORE_RS12190
uniprot id: B8D1E7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

373903:HORE RS04790
gene id: 373903:HORE_RS04790
uniprot id: B8CWJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell inner membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).

373903:HORE RS02180
gene id: 373903:HORE_RS02180
uniprot id: B8D1T9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

373903:HORE RS07700
gene id: 373903:HORE_RS07700
uniprot id: B8CY60
names: Caution
names: Function
names: Similarity
messages: Belongs to the UbiX/PAD1 family.
messages: Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

373903:HORE RS04525
gene id: 373903:HORE_RS04525
uniprot id: B8CWF0
names: Function
names: Similarity
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

373903:HORE RS05150
gene id: 373903:HORE_RS05150
uniprot id: B8CWR7
names: Similarity
messages: Belongs to the RemA family.

373903:HORE RS00860
gene id: 373903:HORE_RS00860
uniprot id: B8D0U2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

373903:HORE RS05835
gene id: 373903:HORE_RS05835
uniprot id: B8CX47
names: Subcellular Location Annotation
messages: Membrane

373903:HORE RS02435
gene id: 373903:HORE_RS02435
uniprot id: B8D1Y9
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

373903:HORE RS04995
gene id: 373903:HORE_RS04995
uniprot id: B8CWN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

373903:HORE RS01445
gene id: 373903:HORE_RS01445
uniprot id: B8D157
names: Similarity
messages: Belongs to the shaker potassium channel beta subunit family.

373903:HORE RS10215
gene id: 373903:HORE_RS10215
uniprot id: B8CZK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

373903:HORE RS01300
gene id: 373903:HORE_RS01300
uniprot id: B8D129
names: Subcellular Location Annotation
messages: Membrane

373903:HORE RS05665
gene id: 373903:HORE_RS05665
uniprot id: B8CX17
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.

373903:HORE RS09275
gene id: 373903:HORE_RS09275
uniprot id: B8CZ14
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell inner membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

373903:HORE RS01890
gene id: 373903:HORE_RS01890
uniprot id: B8D1N4
names: Similarity
messages: Belongs to the peptidase S14 family.

373903:HORE RS05840
gene id: 373903:HORE_RS05840
uniprot id: B8CX48
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

373903:HORE RS04235
gene id: 373903:HORE_RS04235
uniprot id: B8CW93
names: Function
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.
messages: This protein is a Fe-Mo-cofactor biosynthetic component.

373903:HORE RS11470
gene id: 373903:HORE_RS11470
uniprot id: B8D0M3
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

373903:HORE RS02095
gene id: 373903:HORE_RS02095
uniprot id: B8D1S4
names: Similarity
messages: Belongs to the HypE family.

373903:HORE RS09585
gene id: 373903:HORE_RS09585
uniprot id: B8CZ78
names: Function
names: Similarity
messages: Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).

373903:HORE RS06100
gene id: 373903:HORE_RS06100
uniprot id: B8CX97
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

373903:HORE RS01610
gene id: 373903:HORE_RS01610
uniprot id: B8D1I3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transcriptional regulatory Rex family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.

373903:HORE RS04905
gene id: 373903:HORE_RS04905
uniprot id: B8CWL9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell inner membrane
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

373903:HORE RS08570
gene id: 373903:HORE_RS08570
uniprot id: B8CYM5
names: Similarity
messages: Belongs to the glutamate synthase family.

373903:HORE RS05140
gene id: 373903:HORE_RS05140
uniprot id: B8CWR5
names: Function
names: Similarity
names: Subunit
messages: Associates with stalled 50S ribosomal subunits.
messages: Belongs to the NEMF family.
messages: Part of the ribosome quality control system (RQC). Recruits Ala-charged tRNA and directs the elongation of stalled nascent chains on 50S ribosomal subunits, leading to non-templated C-terminal Ala extensions (Ala tail). The Ala tail promotes nascent chain degradation. May add between 1 and at least 8 Ala residues. Binds to stalled 50S ribosomal subunits.

373903:HORE RS07825
gene id: 373903:HORE_RS07825
uniprot id: B8CY83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

373903:HORE RS08410
gene id: 373903:HORE_RS08410
uniprot id: B8CYJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.

373903:HORE RS00420
gene id: 373903:HORE_RS00420
uniprot id: B8D074
names: Similarity
messages: Belongs to the BMP lipoprotein family.

373903:HORE RS03345
gene id: 373903:HORE_RS03345
uniprot id: B8D2G1
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

373903:HORE RS11545
gene id: 373903:HORE_RS11545
uniprot id: B8D0N7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NlpA lipoprotein family.
messages: Membrane

373903:HORE RS02995
gene id: 373903:HORE_RS02995
uniprot id: B8D291
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

373903:HORE RS01595
gene id: 373903:HORE_RS01595
uniprot id: B8D1I0
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

373903:HORE RS04220
gene id: 373903:HORE_RS04220
uniprot id: B8CW90
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

373903:HORE RS00825
gene id: 373903:HORE_RS00825
uniprot id: B8D0T5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

373903:HORE RS00610
gene id: 373903:HORE_RS00610
uniprot id: B8D0A8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

373903:HORE RS09220
gene id: 373903:HORE_RS09220
uniprot id: B8CZ03
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

373903:HORE RS06960
gene id: 373903:HORE_RS06960
uniprot id: B8CXR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

373903:HORE RS04650
gene id: 373903:HORE_RS04650
uniprot id: B8CWH3
names: Similarity
messages: Belongs to the UPF0236 family.

373903:HORE RS04315
gene id: 373903:HORE_RS04315
uniprot id: B8CWA9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

373903:HORE RS08975
gene id: 373903:HORE_RS08975
uniprot id: B8CYV5
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

373903:HORE RS00405
gene id: 373903:HORE_RS00405
uniprot id: B8D071
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

373903:HORE RS01665
gene id: 373903:HORE_RS01665
uniprot id: B8D1J4
names: Similarity
messages: Belongs to the UPF0342 family.

373903:HORE RS00535
gene id: 373903:HORE_RS00535
uniprot id: B8D093
names: Activity Regulation
names: Function
names: Similarity
messages: Appears to be allosterically activated by the binding of pArg-containing polypeptides to the pArg-binding pocket localized in the C-terminal domain of McsB.
messages: Belongs to the ATP:guanido phosphotransferase family.
messages: Catalyzes the specific phosphorylation of arginine residues in proteins.

373903:HORE RS07715
gene id: 373903:HORE_RS07715
uniprot id: B8CY63
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

373903:HORE RS07625
gene id: 373903:HORE_RS07625
uniprot id: B8CY45
names: Subcellular Location Annotation
messages: Membrane

373903:HORE RS02570
gene id: 373903:HORE_RS02570
uniprot id: B8D216
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

373903:HORE RS10600
gene id: 373903:HORE_RS10600
uniprot id: B8CZU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

373903:HORE RS08795
gene id: 373903:HORE_RS08795
uniprot id: B8CYR9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.