368407:MEMAR RS06430
gene id: 368407:MEMAR_RS06430
uniprot id: A3CV41
names: Function
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Rubredoxin is a small nonheme, iron protein lacking acid-labile sulfide. Its single Fe, chelated to 4 Cys, functions as an electron acceptor and may also stabilize the conformation of the molecule.

368407:MEMAR RS00100
gene id: 368407:MEMAR_RS00100
uniprot id: A3CRF7
names: Subcellular Location Annotation
messages: Membrane

368407:MEMAR RS02345
gene id: 368407:MEMAR_RS02345
uniprot id: A3CSR5
names: Similarity
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.

368407:MEMAR RS02380
gene id: 368407:MEMAR_RS02380
uniprot id: A3CSS3
names: Subcellular Location Annotation
messages: Cytoplasm

368407:MEMAR RS01960
gene id: 368407:MEMAR_RS01960
uniprot id: A3CSJ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

368407:MEMAR RS00130
gene id: 368407:MEMAR_RS00130
uniprot id: A3CRG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

368407:MEMAR RS05265
gene id: 368407:MEMAR_RS05265
uniprot id: A3CUF4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

368407:MEMAR RS00280
gene id: 368407:MEMAR_RS00280
uniprot id: A3CRJ2
names: Similarity
messages: Belongs to the DMRL synthase family.

368407:MEMAR RS05625
gene id: 368407:MEMAR_RS05625
uniprot id: A3CUM6
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

368407:MEMAR RS00770
gene id: 368407:MEMAR_RS00770
uniprot id: A3CRU5
names: Subcellular Location Annotation
messages: Membrane

368407:MEMAR RS08905
gene id: 368407:MEMAR_RS08905
uniprot id: A3CWJ0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IPP isomerase type 2 family.
messages: Cytoplasm
messages: Homooctamer. Dimer of tetramers.
messages: Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

368407:MEMAR RS05675
gene id: 368407:MEMAR_RS05675
uniprot id: A3CUP0
names: Similarity
messages: Belongs to the HsdR family.

368407:MEMAR RS02855
gene id: 368407:MEMAR_RS02855
uniprot id: A3CT17
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Part of the 30S ribosomal subunit. Contacts protein S4.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

368407:MEMAR RS01300
gene id: 368407:MEMAR_RS01300
uniprot id: A3CS59
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class III (archaeal) subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

368407:MEMAR RS07460
gene id: 368407:MEMAR_RS07460
uniprot id: A3CVQ3
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TFE family.
messages: Monomer. Interaction with RNA polymerase subunits RpoF and RpoE is necessary for Tfe stimulatory transcription activity. Able to interact with Tbp and RNA polymerase in the absence of DNA promoter. Interacts both with the preinitiation and elongation complexes.
messages: The winged helix domain is involved in binding to DNA in the preinitiation complex.
messages: Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes. Seems to translocate with the RNA polymerase following initiation and acts by binding to the non template strand of the transcription bubble in elongation complexes.

368407:MEMAR RS04000
gene id: 368407:MEMAR_RS04000
uniprot id: A3CTQ0
names: Similarity
messages: Belongs to the DtxR/MntR family.

368407:MEMAR RS04885
gene id: 368407:MEMAR_RS04885
uniprot id: A3CU77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane

368407:MEMAR RS06040
gene id: 368407:MEMAR_RS06040
uniprot id: A3CUW1
names: Similarity
messages: Belongs to the serpin family.

368407:MEMAR RS09565
gene id: 368407:MEMAR_RS09565
uniprot id: A3CWW4
names: Similarity
messages: Belongs to the NifD/NifK/NifE/NifN family.

368407:MEMAR RS03000
gene id: 368407:MEMAR_RS03000
uniprot id: A3CT46
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the methyl-coenzyme M reductase alpha subunit family.
messages: Binds 2 coenzyme F430 non-covalently per MCR complex. Coenzyme F430 is a yellow nickel porphinoid. Methyl-coenzyme-M reductase is activated when the enzyme-bound coenzyme F430 is reduced to the Ni(I) oxidation state.
messages: Component of the methyl-coenzyme M reductase (MCR) I that catalyzes the reductive cleavage of methyl-coenzyme M (CoM-S-CH3 or 2-(methylthio)ethanesulfonate) using coenzyme B (CoB or 7-mercaptoheptanoylthreonine phosphate) as reductant which results in the production of methane and the mixed heterodisulfide of CoB and CoM (CoM-S-S-CoB). This is the final step in methanogenesis.
messages: Hexamer of two alpha, two beta, and two gamma chains.
messages: MCR is a hexamer of two alpha, two beta, and two gamma chains, forming a dimer of heterotrimers.

368407:MEMAR RS09875
gene id: 368407:MEMAR_RS09875
uniprot id: A3CX27
names: Subcellular Location Annotation
messages: Membrane

368407:MEMAR RS06690
gene id: 368407:MEMAR_RS06690
uniprot id: A3CV94
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

368407:MEMAR RS05215
gene id: 368407:MEMAR_RS05215
uniprot id: A3CUE3
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

368407:MEMAR RS07605
gene id: 368407:MEMAR_RS07605
uniprot id: A3CVT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC41A transporter family.
messages: Membrane

368407:MEMAR RS10130
gene id: 368407:MEMAR_RS10130
uniprot id: A3CX76
names: Cofactor
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS27 family.
messages: Binds 1 zinc ion per subunit.

368407:MEMAR RS01490
gene id: 368407:MEMAR_RS01490
uniprot id: A3CS81
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal Rpo5/eukaryotic RPB5 RNA polymerase subunit family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

368407:MEMAR RS07705
gene id: 368407:MEMAR_RS07705
uniprot id: A3CVV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM19 family.
messages: Membrane

368407:MEMAR RS07415
gene id: 368407:MEMAR_RS07415
uniprot id: A3CVP4
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

368407:MEMAR RS06935
gene id: 368407:MEMAR_RS06935
uniprot id: A3CVE4
names: Similarity
messages: Belongs to the UPF0047 family.

368407:MEMAR RS00305
gene id: 368407:MEMAR_RS00305
uniprot id: A3CRJ7
names: Subcellular Location Annotation
messages: Membrane

368407:MEMAR RS03565
gene id: 368407:MEMAR_RS03565
uniprot id: A3CTG3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

368407:MEMAR RS04110
gene id: 368407:MEMAR_RS04110
uniprot id: A3CTS2
names: Function
names: Similarity
messages: Belongs to the adenylate cyclase family. DacZ subfamily.
messages: Diadenylate cyclase that catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP is a second messenger for intracellular signal transduction involved in the control of important regulatory processes such as osmoregulation.

368407:MEMAR RS11285
gene id: 368407:MEMAR_RS11285
uniprot id: A3CXV9
names: Subcellular Location Annotation
messages: Membrane

368407:MEMAR RS04830
gene id: 368407:MEMAR_RS04830
uniprot id: A3CU66
names: Similarity
messages: Belongs to the HMBS family.

368407:MEMAR RS02090
gene id: 368407:MEMAR_RS02090
uniprot id: A3CSL7
names: Subcellular Location Annotation
messages: Membrane

368407:MEMAR RS08225
gene id: 368407:MEMAR_RS08225
uniprot id: A3CW56
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic/archaeal RNase P protein component 2 family.
messages: Consists of a catalytic RNA component and at least 4-5 protein subunits.
messages: Cytoplasm
messages: Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.

368407:MEMAR RS02730
gene id: 368407:MEMAR_RS02730
uniprot id: A3CSZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mer family.
messages: Catalyzes the reversible reduction of methylene-H(4)MPT to methyl-H(4)MPT.
messages: Cytoplasm

368407:MEMAR RS09330
gene id: 368407:MEMAR_RS09330
uniprot id: A3CWR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

368407:MEMAR RS00380
gene id: 368407:MEMAR_RS00380
uniprot id: A3CRL2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

368407:MEMAR RS00365
gene id: 368407:MEMAR_RS00365
uniprot id: A3CRK9
names: Similarity
messages: Belongs to the TrpC family.

368407:MEMAR RS09880
gene id: 368407:MEMAR_RS09880
uniprot id: A3CX28
names: Subcellular Location Annotation
messages: Membrane

368407:MEMAR RS00125
gene id: 368407:MEMAR_RS00125
uniprot id: A3CRG2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

368407:MEMAR RS08710
gene id: 368407:MEMAR_RS08710
uniprot id: A3CWF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

368407:MEMAR RS05035
gene id: 368407:MEMAR_RS05035
uniprot id: A3CUA7
names: Similarity
messages: Belongs to the HupF/HypC family.

368407:MEMAR RS07680
gene id: 368407:MEMAR_RS07680
uniprot id: A3CVU7
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

368407:MEMAR RS09680
gene id: 368407:MEMAR_RS09680
uniprot id: A3CWY8
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase Pus10 family.
messages: Responsible for synthesis of pseudouridine from uracil-54 and uracil-55 in the psi GC loop of transfer RNAs.

368407:MEMAR RS09060
gene id: 368407:MEMAR_RS09060
uniprot id: A3CWL6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

368407:MEMAR RS05230
gene id: 368407:MEMAR_RS05230
uniprot id: A3CUE6
names: Similarity
messages: Belongs to the PurH family.

368407:MEMAR RS03105
gene id: 368407:MEMAR_RS03105
uniprot id: A3CT66
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

368407:MEMAR RS02790
gene id: 368407:MEMAR_RS02790
uniprot id: A3CT04
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

368407:MEMAR RS01990
gene id: 368407:MEMAR_RS01990
uniprot id: A3CSJ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein P1/P2 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the 50S ribosomal subunit. Homodimer, it forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Forms a heptameric L10(L12)2(L12)2(L12)2 complex, where L10 forms an elongated spine to which the L12 dimers bind in a sequential fashion.

368407:MEMAR RS09415
gene id: 368407:MEMAR_RS09415
uniprot id: A3CWT4
names: Subcellular Location Annotation
messages: Membrane

368407:MEMAR RS10665
gene id: 368407:MEMAR_RS10665
uniprot id: A3CXI3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

368407:MEMAR RS07935
gene id: 368407:MEMAR_RS07935
uniprot id: A3CW00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FNT transporter (TC 2.A.44) family.
messages: Membrane

368407:MEMAR RS05640
gene id: 368407:MEMAR_RS05640
uniprot id: A3CUN1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

368407:MEMAR RS11080
gene id: 368407:MEMAR_RS11080
uniprot id: A3CXR7
names: Function
names: Similarity
messages: Belongs to the GTP-dependent DPCK family.
messages: Catalyzes the GTP-dependent phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (CoA).

368407:MEMAR RS07160
gene id: 368407:MEMAR_RS07160
uniprot id: A3CVJ1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic-type primase large subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Heterodimer of a small subunit (PriS) and a large subunit (PriL).
messages: Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair.

368407:MEMAR RS11595
gene id: 368407:MEMAR_RS11595
uniprot id: A3CY23
names: Similarity
messages: Belongs to the OMP decarboxylase family.

368407:MEMAR RS07770
gene id: 368407:MEMAR_RS07770
uniprot id: A3CVW6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TOP6A family.
messages: Homodimer. Heterotetramer of two Top6A and two Top6B chains.
messages: Relaxes both positive and negative superturns and exhibits a strong decatenase activity.

368407:MEMAR RS01435
gene id: 368407:MEMAR_RS01435
uniprot id: A3CS84
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds at least 2 Zn(2+) per subunit.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Forms the clamp head domain.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

368407:MEMAR RS09240
gene id: 368407:MEMAR_RS09240
uniprot id: A3CWQ2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

368407:MEMAR RS06345
gene id: 368407:MEMAR_RS06345
uniprot id: A3CV24
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

368407:MEMAR RS02705
gene id: 368407:MEMAR_RS02705
uniprot id: A3CSY6
names: Similarity
messages: Belongs to the intimin/invasin family.

368407:MEMAR RS10520
gene id: 368407:MEMAR_RS10520
uniprot id: A3CXF3
names: Similarity
messages: Belongs to the peptidase C56 family.

368407:MEMAR RS02645
gene id: 368407:MEMAR_RS02645
uniprot id: A3CSX5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the methyltransferase superfamily. Fibrillarin family.
messages: Interacts with nop5. Component of box C/D small ribonucleoprotein (sRNP) particles that contain rpl7ae, FlpA and nop5, plus a guide RNA.
messages: Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA.

368407:MEMAR RS06210
gene id: 368407:MEMAR_RS06210
uniprot id: A3CUZ3
names: Similarity
messages: Belongs to the disproportionating enzyme family.

368407:MEMAR RS01195
gene id: 368407:MEMAR_RS01195
uniprot id: A3CS40
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

368407:MEMAR RS01340
gene id: 368407:MEMAR_RS01340
uniprot id: A3CS67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Membrane

368407:MEMAR RS09105
gene id: 368407:MEMAR_RS09105
uniprot id: A3CWM5
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

368407:MEMAR RS01420
gene id: 368407:MEMAR_RS01420
uniprot id: A3CS81
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal Rpo5/eukaryotic RPB5 RNA polymerase subunit family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

368407:MEMAR RS01230
gene id: 368407:MEMAR_RS01230
uniprot id: A3CS47
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCH family.
messages: Catalyzes the reversible interconversion of 5-formyl-H(4)MPT to methenyl-H(4)MPT(+).
messages: Cytoplasm

368407:MEMAR RS06380
gene id: 368407:MEMAR_RS06380
uniprot id: A3CV31
names: Function
names: Similarity
messages: Belongs to the archaeal-type DHQ synthase family.
messages: Catalyzes the oxidative deamination and cyclization of 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonic acid (ADH) to yield 3-dehydroquinate (DHQ), which is fed into the canonical shikimic pathway of aromatic amino acid biosynthesis.

368407:MEMAR RS08200
gene id: 368407:MEMAR_RS08200
uniprot id: A3CW50
names: Similarity
messages: Belongs to the CTAG/PCC1 family.

368407:MEMAR RS00805
gene id: 368407:MEMAR_RS00805
uniprot id: A3CRV2
names: Subcellular Location Annotation
messages: Membrane

368407:MEMAR RS04200
gene id: 368407:MEMAR_RS04200
uniprot id: A3CTU1
names: Similarity
messages: Belongs to the UPF0212 family.

368407:MEMAR RS04315
gene id: 368407:MEMAR_RS04315
uniprot id: A3CTW4
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

368407:MEMAR RS00320
gene id: 368407:MEMAR_RS00320
uniprot id: A3CRK0
names: Subcellular Location Annotation
messages: Membrane

368407:MEMAR RS10010
gene id: 368407:MEMAR_RS10010
uniprot id: A3CX52
names: Similarity
names: Subunit
messages: Belongs to the HTP reductase family.
messages: Homodimer.

368407:MEMAR RS10650
gene id: 368407:MEMAR_RS10650
uniprot id: A3CXI0
names: Similarity
messages: Belongs to the AAA ATPase family. CDC48 subfamily.

368407:MEMAR RS04910
gene id: 368407:MEMAR_RS04910
uniprot id: A3CU82
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm
messages: Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.

368407:MEMAR RS09450
gene id: 368407:MEMAR_RS09450
uniprot id: A3CWU1
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

368407:MEMAR RS05090
gene id: 368407:MEMAR_RS05090
uniprot id: A3CUB9
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.

368407:MEMAR RS07265
gene id: 368407:MEMAR_RS07265
uniprot id: A3CVL1
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

368407:MEMAR RS02840
gene id: 368407:MEMAR_RS02840
uniprot id: A3CT14
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL32 family.

368407:MEMAR RS10620
gene id: 368407:MEMAR_RS10620
uniprot id: A3CXH4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 2 subfamily.
messages: Binds 3 Mg(2+) cations per subunit. The strongest magnesium site (Mg1) is bound to the beta- and gamma-phosphates of ATP and four water molecules complete its coordination sphere.
messages: Cytoplasm
messages: Homodimer.

368407:MEMAR RS02945
gene id: 368407:MEMAR_RS02945
uniprot id: A3CT35
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

368407:MEMAR RS03850
gene id: 368407:MEMAR_RS03850
uniprot id: A3CTM0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

368407:MEMAR RS07685
gene id: 368407:MEMAR_RS07685
uniprot id: A3CVU8
names: Function
names: Similarity
messages: Belongs to the MfnB family.
messages: Catalyzes the formation of 4-(hydroxymethyl)-2-furancarboxaldehyde phosphate (4-HFC-P) from two molecules of glyceraldehyde-3-P (GA-3-P).

368407:MEMAR RS09705
gene id: 368407:MEMAR_RS09705
uniprot id: A3CWZ3
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL20 family.
messages: Part of the 50S ribosomal subunit. Binds 23S rRNA.

368407:MEMAR RS02995
gene id: 368407:MEMAR_RS02995
uniprot id: A3CT45
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MtrE family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of a complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step.
messages: The complex is composed of 8 subunits; MtrA, MtrB, MtrC, MtrD, MtrE, MtrF, MtrG and MtrH.

368407:MEMAR RS02580
gene id: 368407:MEMAR_RS02580
uniprot id: A3CSW3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CbiN family.
messages: Cell membrane
messages: Forms an energy-coupling factor (ECF) transporter complex composed of an ATP-binding protein (A component, CbiO), a transmembrane protein (T component, CbiQ) and 2 possible substrate-capture proteins (S components, CbiM and CbiN) of unknown stoichimetry.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import.

368407:MEMAR RS06965
gene id: 368407:MEMAR_RS06965
uniprot id: A3CVF0
names: Similarity
messages: Belongs to the UPF0173 family.

368407:MEMAR RS07545
gene id: 368407:MEMAR_RS07545
uniprot id: A3CVS0
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

368407:MEMAR RS09470
gene id: 368407:MEMAR_RS09470
uniprot id: A3CWU5
names: Function
names: Similarity
messages: Belongs to the archaeal SPP-like hydrolase family.
messages: Catalyzes the dephosphorylation of 2-phosphoglycolate.

368407:MEMAR RS06150
gene id: 368407:MEMAR_RS06150
uniprot id: A3CUY3
names: Caution
names: Function
names: Similarity
messages: Belongs to the TBP family.
messages: General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

368407:MEMAR RS06055
gene id: 368407:MEMAR_RS06055
uniprot id: A3CUW4
names: Similarity
messages: Belongs to the activator 1 small subunits family. RfcS subfamily.

368407:MEMAR RS01305
gene id: 368407:MEMAR_RS01305
uniprot id: A3CS60
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Degrades polypeptides processively.
messages: Belongs to the peptidase S16 family. Archaeal LonB subfamily.
messages: Cell membrane
messages: Homohexamer. Organized in a ring with a central cavity.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

368407:MEMAR RS02065
gene id: 368407:MEMAR_RS02065
uniprot id: A3CSL3
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Part of the 30S ribosomal subunit.

368407:MEMAR RS11095
gene id: 368407:MEMAR_RS11095
uniprot id: A3CXS0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Fe(2+) ion per subunit.
messages: Component of the KEOPS complex that consists of Kae1, Bud32, Cgi121 and Pcc1; the whole complex dimerizes.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the protein kinase superfamily. Tyr protein kinase family. BUD32 subfamily.
messages: In the N-terminal section; belongs to the KAE1 / TsaD family.
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction. The Bud32 domain probably displays kinase activity that regulates Kae1 function.

368407:MEMAR RS12325
gene id: 368407:MEMAR_RS12325
uniprot id: A3CYG8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
messages: Cytoplasm
messages: Homotetramer.

368407:MEMAR RS05255
gene id: 368407:MEMAR_RS05255
uniprot id: A3CUF2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.
messages: Catalyzes the condensation of pyruvate and acetyl-coenzyme A to form (R)-citramalate.
messages: Homodimer.

368407:MEMAR RS12240
gene id: 368407:MEMAR_RS12240
uniprot id: A3CYF1
names: Similarity
messages: Belongs to the glycogen phosphorylase family.

368407:MEMAR RS02825
gene id: 368407:MEMAR_RS02825
uniprot id: A3CT11
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles.
messages: Part of the 30S ribosomal subunit.

368407:MEMAR RS11155
gene id: 368407:MEMAR_RS11155
uniprot id: A3CXT0
names: Subcellular Location Annotation
messages: Membrane

368407:MEMAR RS03520
gene id: 368407:MEMAR_RS03520
uniprot id: A3CTF4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL8 family.
messages: Cytoplasm
messages: Multifunctional RNA-binding protein that recognizes the K-turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs.
messages: Part of the 50S ribosomal subunit. Probably part of the RNase P complex.

368407:MEMAR RS12175
gene id: 368407:MEMAR_RS12175
uniprot id: A3CYD8
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

368407:MEMAR RS07360
gene id: 368407:MEMAR_RS07360
uniprot id: A3CVN3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

368407:MEMAR RS02795
gene id: 368407:MEMAR_RS02795
uniprot id: A3CT05
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic/archaeal RNase P protein component 1 family.
messages: Consists of a catalytic RNA component and at least 4-5 protein subunits.
messages: Cytoplasm
messages: Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.

368407:MEMAR RS05305
gene id: 368407:MEMAR_RS05305
uniprot id: A3CUG2
names: Similarity
messages: Belongs to the thioesterase PaaI family.

368407:MEMAR RS03900
gene id: 368407:MEMAR_RS03900
uniprot id: A3CTN1
names: Similarity
messages: Belongs to the DNA polymerase type-B family.

368407:MEMAR RS02690
gene id: 368407:MEMAR_RS02690
uniprot id: A3CSY3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: S-layer

368407:MEMAR RS07450
gene id: 368407:MEMAR_RS07450
uniprot id: A3CVQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the aTrm56 family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs.

368407:MEMAR RS08320
gene id: 368407:MEMAR_RS08320
uniprot id: A3CW74
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. DGGGP synthase subfamily.
messages: Cell membrane
messages: Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids.

368407:MEMAR RS03560
gene id: 368407:MEMAR_RS03560
uniprot id: A3CTG2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

368407:MEMAR RS02225
gene id: 368407:MEMAR_RS02225
uniprot id: A3CSP3
names: Similarity
messages: Belongs to the serpin family.

368407:MEMAR RS09055
gene id: 368407:MEMAR_RS09055
uniprot id: A3CWL5
names: Similarity
messages: Belongs to the SAICAR synthetase family.

368407:MEMAR RS01370
gene id: 368407:MEMAR_RS01370
uniprot id: A3CS73
names: Function
names: Similarity
messages: Belongs to the V-ATPase D subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

368407:MEMAR RS09670
gene id: 368407:MEMAR_RS09670
uniprot id: A3CWY6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic RPB4 RNA polymerase subunit family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. This subunit is less well bound than the others.
messages: Part of the RNA polymerase complex. Forms a stalk with Rpo7 that extends from the main structure.

368407:MEMAR RS03025
gene id: 368407:MEMAR_RS03025
uniprot id: A3CT51
names: Similarity
messages: Belongs to the FwdC/FmdC family.

368407:MEMAR RS08330
gene id: 368407:MEMAR_RS08330
uniprot id: A3CW75
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family.
messages: Dimethylates a single guanine residue at position 26 of a number of tRNAs using S-adenosyl-L-methionine as donor of the methyl groups.

368407:MEMAR RS09370
gene id: 368407:MEMAR_RS09370
uniprot id: A3CWS7
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

368407:MEMAR RS07690
gene id: 368407:MEMAR_RS07690
uniprot id: A3CVU9
names: Similarity
messages: Belongs to the HisA/HisF family.

368407:MEMAR RS11590
gene id: 368407:MEMAR_RS11590
uniprot id: A3CY22
names: Similarity
messages: Belongs to the deoxyhypusine synthase family.

368407:MEMAR RS01310
gene id: 368407:MEMAR_RS01310
uniprot id: A3CS61
names: Similarity
messages: Belongs to the peptidase U62 family.

368407:MEMAR RS00210
gene id: 368407:MEMAR_RS00210
uniprot id: A3CRH9
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-stimulated subfamily.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Requires K(+) for maximal activity.
messages: Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na(+) movement across the membrane.

368407:MEMAR RS01710
gene id: 368407:MEMAR_RS01710
uniprot id: A3CSE0
names: Subcellular Location Annotation
messages: Membrane

368407:MEMAR RS08230
gene id: 368407:MEMAR_RS08230
uniprot id: A3CW57
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic/archaeal RNase P protein component 3 family.
messages: Consists of a catalytic RNA component and at least 4-5 protein subunits.
messages: Cytoplasm
messages: Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.

368407:MEMAR RS06390
gene id: 368407:MEMAR_RS06390
uniprot id: A3CV33
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DeoC/FbaB aldolase family. ADHS subfamily.
messages: Catalyzes a transaldol reaction between 6-deoxy-5-ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids.
messages: Homodecamer.

368407:MEMAR RS03060
gene id: 368407:MEMAR_RS03060
uniprot id: A3CT58
names: Similarity
messages: Belongs to the HdrC family.

368407:MEMAR RS00315
gene id: 368407:MEMAR_RS00315
uniprot id: A3CRJ9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

368407:MEMAR RS05045
gene id: 368407:MEMAR_RS05045
uniprot id: A3CUB0
names: Cofactor
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Binds 1 zinc ion per subunit. The zinc ion is important for the structural integrity of the protein.

368407:MEMAR RS00065
gene id: 368407:MEMAR_RS00065
uniprot id: A3CRF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

368407:MEMAR RS03005
gene id: 368407:MEMAR_RS03005
uniprot id: A3CT47
names: Similarity
names: Subunit
messages: Belongs to the methyl-coenzyme M reductase gamma subunit family.
messages: Hexamer of two alpha, two beta, and two gamma chains.
messages: MCR is a hexamer of two alpha, two beta, and two gamma chains, forming a dimer of heterotrimers.

368407:MEMAR RS11640
gene id: 368407:MEMAR_RS11640
uniprot id: A3CY32
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the archaeal riboflavin kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN).

368407:MEMAR RS10545
gene id: 368407:MEMAR_RS10545
uniprot id: A3CXF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamine synthetase family.
messages: Cytoplasm

368407:MEMAR RS07365
gene id: 368407:MEMAR_RS07365
uniprot id: A3CVN4
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

368407:MEMAR RS11100
gene id: 368407:MEMAR_RS11100
uniprot id: A3CXS1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

368407:MEMAR RS07135
gene id: 368407:MEMAR_RS07135
uniprot id: A3CVI6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

368407:MEMAR RS10295
gene id: 368407:MEMAR_RS10295
uniprot id: A3CXB0
names: Subcellular Location Annotation
messages: Membrane

368407:MEMAR RS11070
gene id: 368407:MEMAR_RS11070
uniprot id: A3CXR5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic RPB7/RPC8 RNA polymerase subunit family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Forms 2 domains with an elongated structure; Rpo4 packs into the hinge region between the 2 domains.
messages: Nucleus
messages: Part of the RNA polymerase complex. Forms a stalk with Rpo4 that extends from the main structure.

368407:MEMAR RS01430
gene id: 368407:MEMAR_RS01430
uniprot id: A3CS83
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

368407:MEMAR RS05110
gene id: 368407:MEMAR_RS05110
uniprot id: A3CUC2
names: Similarity
messages: Belongs to the UPF0111 family.

368407:MEMAR RS01185
gene id: 368407:MEMAR_RS01185
uniprot id: A3CS38
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.
messages: Rubredoxin is a small nonheme, iron protein lacking acid-labile sulfide. Its single Fe, chelated to 4 Cys, functions as an electron acceptor and may also stabilize the conformation of the molecule.

368407:MEMAR RS11990
gene id: 368407:MEMAR_RS11990
uniprot id: A3CYA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S16 family.
messages: Membrane

368407:MEMAR RS10145
gene id: 368407:MEMAR_RS10145
uniprot id: A3CX79
names: Subcellular Location Annotation
messages: Membrane

368407:MEMAR RS06840
gene id: 368407:MEMAR_RS06840
uniprot id: A3CVC6
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

368407:MEMAR RS11205
gene id: 368407:MEMAR_RS11205
uniprot id: A3CXU2
names: Similarity
messages: Belongs to the UPF0210 family.

368407:MEMAR RS01605
gene id: 368407:MEMAR_RS01605
uniprot id: A3CSB8
names: Similarity
messages: Belongs to the glutamine synthetase family.

368407:MEMAR RS01970
gene id: 368407:MEMAR_RS01970
uniprot id: A3CSJ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SPT5 family.
messages: Belongs to the archaeal Spt5 family.
messages: Heterodimer composed of Spt4 and Spt5. Interacts with RNA polymerase (RNAP).
messages: Stimulates transcription elongation.

368407:MEMAR RS01035
gene id: 368407:MEMAR_RS01035
uniprot id: A3CS07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

368407:MEMAR RS08895
gene id: 368407:MEMAR_RS08895
uniprot id: A3CWI8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GHMP kinase family. Mevalonate kinase subfamily.
messages: Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)-mevalonate 5-phosphate (MVAP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

368407:MEMAR RS06095
gene id: 368407:MEMAR_RS06095
uniprot id: A3CUX2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the archaeal dihydroneopterin aldolase family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin (H2Neo) to 6-hydroxymethyl-7,8-dihydropterin (6-HMD).
messages: Homotetramer.

368407:MEMAR RS01365
gene id: 368407:MEMAR_RS01365
uniprot id: A3CS72
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit.

368407:MEMAR RS03970
gene id: 368407:MEMAR_RS03970
uniprot id: A3CTP4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.

368407:MEMAR RS08775
gene id: 368407:MEMAR_RS08775
uniprot id: A3CWG4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP). It is probably the precursor of glycosyl carrier lipids.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

368407:MEMAR RS09300
gene id: 368407:MEMAR_RS09300
uniprot id: A3CWR3
names: Subcellular Location Annotation
messages: Membrane

368407:MEMAR RS05665
gene id: 368407:MEMAR_RS05665
uniprot id: A3CUN7
names: Subcellular Location Annotation
messages: Membrane

368407:MEMAR RS08665
gene id: 368407:MEMAR_RS08665
uniprot id: A3CWE2
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus
messages: Repair polymerase that plays a key role in base-excision repair. Has 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity that removes the 5' sugar phosphate and also acts as a DNA polymerase that adds one nucleotide to the 3' end of the arising single-nucleotide gap. Conducts 'gap-filling' DNA synthesis in a stepwise distributive fashion rather than in a processive fashion as for other DNA polymerases.

368407:MEMAR RS00970
gene id: 368407:MEMAR_RS00970
uniprot id: A3CRZ0
names: Similarity
messages: Belongs to the acylphosphatase family.

368407:MEMAR RS02850
gene id: 368407:MEMAR_RS02850
uniprot id: A3CT16
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

368407:MEMAR RS01510
gene id: 368407:MEMAR_RS01510
uniprot id: A3CS85
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Forms part of the jaw domain.
messages: Part of the RNA polymerase complex.

368407:MEMAR RS07125
gene id: 368407:MEMAR_RS07125
uniprot id: A3CVI4
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Homodimer.

368407:MEMAR RS08625
gene id: 368407:MEMAR_RS08625
uniprot id: A3CWD4
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

368407:MEMAR RS02985
gene id: 368407:MEMAR_RS02985
uniprot id: A3CT43
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MtrC family.
messages: Cell membrane
messages: Membrane
messages: Part of a complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step.
messages: The complex is composed of 8 subunits; MtrA, MtrB, MtrC, MtrD, MtrE, MtrF, MtrG and MtrH.

368407:MEMAR RS05650
gene id: 368407:MEMAR_RS05650
uniprot id: A3CUN3
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

368407:MEMAR RS08235
gene id: 368407:MEMAR_RS08235
uniprot id: A3CW58
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL15 family.

368407:MEMAR RS07355
gene id: 368407:MEMAR_RS07355
uniprot id: A3CVN2
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

368407:MEMAR RS06455
gene id: 368407:MEMAR_RS06455
uniprot id: A3CV46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

368407:MEMAR RS06830
gene id: 368407:MEMAR_RS06830
uniprot id: A3CVC4
names: Similarity
messages: Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.

368407:MEMAR RS10725
gene id: 368407:MEMAR_RS10725
uniprot id: A3CXJ5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.

368407:MEMAR RS09865
gene id: 368407:MEMAR_RS09865
uniprot id: A3CX25
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.

368407:MEMAR RS07840
gene id: 368407:MEMAR_RS07840
uniprot id: A3CVY1
names: Similarity
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.

368407:MEMAR RS02755
gene id: 368407:MEMAR_RS02755
uniprot id: A3CSZ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L24e.

368407:MEMAR RS05780
gene id: 368407:MEMAR_RS05780
uniprot id: A3CUR1
names: Subcellular Location Annotation
messages: Membrane

368407:MEMAR RS08135
gene id: 368407:MEMAR_RS08135
uniprot id: A3CW38
names: Subunit
messages: Homotetramer.

368407:MEMAR RS02740
gene id: 368407:MEMAR_RS02740
uniprot id: A3CSZ2
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

368407:MEMAR RS11035
gene id: 368407:MEMAR_RS11035
uniprot id: A3CXQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STT3 family.
messages: Membrane

368407:MEMAR RS04525
gene id: 368407:MEMAR_RS04525
uniprot id: A3CU04
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

368407:MEMAR RS07535
gene id: 368407:MEMAR_RS07535
uniprot id: A3CVR8
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.

368407:MEMAR RS03275
gene id: 368407:MEMAR_RS03275
uniprot id: A3CTA2
names: Function
names: Similarity
messages: Belongs to the CDC6/cdc18 family.
messages: Involved in regulation of DNA replication.

368407:MEMAR RS07960
gene id: 368407:MEMAR_RS07960
uniprot id: A3CW05
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family. N(4) subfamily.

368407:MEMAR RS08660
gene id: 368407:MEMAR_RS08660
uniprot id: A3CWE1
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

368407:MEMAR RS02475
gene id: 368407:MEMAR_RS02475
uniprot id: A3CSU2
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

368407:MEMAR RS11005
gene id: 368407:MEMAR_RS11005
uniprot id: A3CXQ2
names: Similarity
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.

368407:MEMAR RS02050
gene id: 368407:MEMAR_RS02050
uniprot id: A3CSL0
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS1 family.

368407:MEMAR RS09630
gene id: 368407:MEMAR_RS09630
uniprot id: A3CWX7
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

368407:MEMAR RS04925
gene id: 368407:MEMAR_RS04925
uniprot id: A3CU85
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-archaeol synthase family.
messages: Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate (DGGGP) and CTP. This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids.
messages: Cell membrane

368407:MEMAR RS01625
gene id: 368407:MEMAR_RS01625
uniprot id: A3CSC2
names: Similarity
messages: Belongs to the AOR/FOR family.

368407:MEMAR RS06575
gene id: 368407:MEMAR_RS06575
uniprot id: A3CV71
names: Subcellular Location Annotation
messages: Membrane

368407:MEMAR RS03510
gene id: 368407:MEMAR_RS03510
uniprot id: A3CTF2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL24 family.
messages: Binds 1 zinc ion per subunit.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L14.

368407:MEMAR RS10660
gene id: 368407:MEMAR_RS10660
uniprot id: A3CXI2
names: Function
names: Similarity
messages: Belongs to the eukaryotic RecA-like protein family. RadB subfamily.
messages: Involved in DNA repair and in homologous recombination. May regulate the cleavage reactions of the branch-structured DNA. Has a very weak ATPase activity that is not stimulated by DNA. Binds DNA but does not promote DNA strands exchange.

368407:MEMAR RS06470
gene id: 368407:MEMAR_RS06470
uniprot id: A3CV49
names: Subcellular Location Annotation
messages: Membrane

368407:MEMAR RS09455
gene id: 368407:MEMAR_RS09455
uniprot id: A3CWU2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

368407:MEMAR RS03425
gene id: 368407:MEMAR_RS03425
uniprot id: A3CTD5
names: Function
names: Similarity
messages: Belongs to the BPG-independent phosphoglycerate mutase family. A-PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

368407:MEMAR RS09270
gene id: 368407:MEMAR_RS09270
uniprot id: A3CWQ8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

368407:MEMAR RS02000
gene id: 368407:MEMAR_RS02000
uniprot id: A3CSK0
names: Similarity
messages: Belongs to the carbamoyltransferase HypF family.

368407:MEMAR RS03515
gene id: 368407:MEMAR_RS03515
uniprot id: A3CTF3
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS28 family.

368407:MEMAR RS05260
gene id: 368407:MEMAR_RS05260
uniprot id: A3CUF3
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

368407:MEMAR RS03270
gene id: 368407:MEMAR_RS03270
uniprot id: A3CTA1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCH family.
messages: Catalyzes the reversible interconversion of 5-formyl-H(4)MPT to methenyl-H(4)MPT(+).
messages: Cytoplasm

368407:MEMAR RS06655
gene id: 368407:MEMAR_RS06655
uniprot id: A3CV87
names: Similarity
messages: Belongs to the peptidase S1C family.

368407:MEMAR RS06705
gene id: 368407:MEMAR_RS06705
uniprot id: A3CV97
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
messages: Cytoplasm
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Non-allosteric.

368407:MEMAR RS03240
gene id: 368407:MEMAR_RS03240
uniprot id: A3CT95
names: Subcellular Location Annotation
messages: Membrane

368407:MEMAR RS10135
gene id: 368407:MEMAR_RS10135
uniprot id: A3CX77
names: Similarity
messages: Belongs to the eIF-2-alpha family.

368407:MEMAR RS04445
gene id: 368407:MEMAR_RS04445
uniprot id: A3CTZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

368407:MEMAR RS08945
gene id: 368407:MEMAR_RS08945
uniprot id: A3CWJ8
names: Subcellular Location Annotation
messages: Membrane

368407:MEMAR RS01630
gene id: 368407:MEMAR_RS01630
uniprot id: A3CSC3
names: Similarity
messages: Belongs to the tRNA methyltransferase O family.

368407:MEMAR RS01515
gene id: 368407:MEMAR_RS01515
uniprot id: A3CS86
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL30 family.

368407:MEMAR RS06895
gene id: 368407:MEMAR_RS06895
uniprot id: A3CVD6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

368407:MEMAR RS10115
gene id: 368407:MEMAR_RS10115
uniprot id: A3CX73
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic-type primase small subunit family.
messages: Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair.
messages: Heterodimer of a small subunit (PriS) and a large subunit (PriL).
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

368407:MEMAR RS08110
gene id: 368407:MEMAR_RS08110
uniprot id: A3CW32
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Involved in protein export.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the protein translocation apparatus. Forms a complex with SecD.

368407:MEMAR RS03150
gene id: 368407:MEMAR_RS03150
uniprot id: A3CT75
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

368407:MEMAR RS12000
gene id: 368407:MEMAR_RS12000
uniprot id: A3CYA3
names: Similarity
messages: Belongs to the phosphohexose mutase family.

368407:MEMAR RS11550
gene id: 368407:MEMAR_RS11550
uniprot id: A3CY14
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

368407:MEMAR RS10200
gene id: 368407:MEMAR_RS10200
uniprot id: A3CX90
names: Similarity
messages: Belongs to the UPF0288 family.

368407:MEMAR RS03745
gene id: 368407:MEMAR_RS03745
uniprot id: A3CTJ9
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged L-seryl-tRNA(Thr).
messages: Cytoplasm
messages: Homodimer.
messages: The N-terminal domain is an archaea-specific tRNA-editing domain that hydrolyzes incorrectly charged L-seryl-tRNA(Thr). Catalysis of tRNA editing is performed by the charged tRNA itself.

368407:MEMAR RS12330
gene id: 368407:MEMAR_RS12330
uniprot id: A3CYG9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 3 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

368407:MEMAR RS08725
gene id: 368407:MEMAR_RS08725
uniprot id: A3CWF4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Participates in transcription termination.

368407:MEMAR RS09860
gene id: 368407:MEMAR_RS09860
uniprot id: A3CX24
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

368407:MEMAR RS07695
gene id: 368407:MEMAR_RS07695
uniprot id: A3CVV0
names: Similarity
messages: Belongs to the thymidylate kinase family.

368407:MEMAR RS10765
gene id: 368407:MEMAR_RS10765
uniprot id: A3CXK3
names: Similarity
messages: Belongs to the HerA family.

368407:MEMAR RS08855
gene id: 368407:MEMAR_RS08855
uniprot id: A3CWH9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal Rpo3/eukaryotic RPB3 RNA polymerase subunit family.
messages: Binds 1 [3Fe-4S] cluster.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

368407:MEMAR RS11695
gene id: 368407:MEMAR_RS11695
uniprot id: A3CY43
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Feedback inhibited by histidine.

368407:MEMAR RS02770
gene id: 368407:MEMAR_RS02770
uniprot id: A3CT00
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

368407:MEMAR RS07975
gene id: 368407:MEMAR_RS07975
uniprot id: A3CW08
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

368407:MEMAR RS06330
gene id: 368407:MEMAR_RS06330
uniprot id: A3CV22
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

368407:MEMAR RS06985
gene id: 368407:MEMAR_RS06985
uniprot id: A3CVF5
names: Subcellular Location Annotation
messages: Membrane

368407:MEMAR RS03110
gene id: 368407:MEMAR_RS03110
uniprot id: A3CT67
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

368407:MEMAR RS01395
gene id: 368407:MEMAR_RS01395
uniprot id: A3CS77
names: Similarity
messages: Belongs to the ParA family. MinD subfamily.

368407:MEMAR RS01745
gene id: 368407:MEMAR_RS01745
uniprot id: A3CSE7
names: Subcellular Location Annotation
messages: Membrane

368407:MEMAR RS04300
gene id: 368407:MEMAR_RS04300
uniprot id: A3CTW1
names: Similarity
messages: Belongs to the Ahb/Nir family.

368407:MEMAR RS01965
gene id: 368407:MEMAR_RS01965
uniprot id: A3CSJ3
names: Subcellular Location Annotation
messages: Membrane

368407:MEMAR RS01675
gene id: 368407:MEMAR_RS01675
uniprot id: A3CSD3
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.

368407:MEMAR RS06870
gene id: 368407:MEMAR_RS06870
uniprot id: A3CVD1
names: Subcellular Location Annotation
messages: Membrane

368407:MEMAR RS04180
gene id: 368407:MEMAR_RS04180
uniprot id: A3CTT6
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate.
messages: Belongs to the asparaginase 1 family. GatD subfamily.
messages: Heterodimer of GatD and GatE.

368407:MEMAR RS08345
gene id: 368407:MEMAR_RS08345
uniprot id: A3CW77
names: Similarity
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.

368407:MEMAR RS11015
gene id: 368407:MEMAR_RS11015
uniprot id: A3CXQ4
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

368407:MEMAR RS00740
gene id: 368407:MEMAR_RS00740
uniprot id: A3CRT9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

368407:MEMAR RS03545
gene id: 368407:MEMAR_RS03545
uniprot id: A3CTF9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CetZ family.
messages: Cytoplasm
messages: Involved in cell shape control.

368407:MEMAR RS01805
gene id: 368407:MEMAR_RS01805
uniprot id: A3CSG0
names: Similarity
names: Subunit
messages: Belongs to the methyl-coenzyme M reductase gamma subunit family.
messages: Hexamer of two alpha, two beta, and two gamma chains.
messages: MCR is a hexamer of two alpha, two beta, and two gamma chains, forming a dimer of heterotrimers.

368407:MEMAR RS10985
gene id: 368407:MEMAR_RS10985
uniprot id: A3CXP8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
messages: Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.
messages: Cytoplasm

368407:MEMAR RS08435
gene id: 368407:MEMAR_RS08435
uniprot id: A3CW95
names: Similarity
messages: Belongs to the glutaredoxin family.

368407:MEMAR RS07780
gene id: 368407:MEMAR_RS07780
uniprot id: A3CVW8
names: Similarity
messages: Belongs to the HepT RNase toxin family.

368407:MEMAR RS01615
gene id: 368407:MEMAR_RS01615
uniprot id: A3CSC0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

368407:MEMAR RS02585
gene id: 368407:MEMAR_RS02585
uniprot id: A3CSW4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CbiM family.
messages: Cell membrane
messages: Forms an energy-coupling factor (ECF) transporter complex composed of an ATP-binding protein (A component, CbiO), a transmembrane protein (T component, CbiQ) and 2 possible substrate-capture proteins (S components, CbiM and CbiN) of unknown stoichimetry.
messages: Membrane
messages: Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import.

368407:MEMAR RS09990
gene id: 368407:MEMAR_RS09990
uniprot id: A3CX48
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

368407:MEMAR RS08220
gene id: 368407:MEMAR_RS08220
uniprot id: A3CW55
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
messages: Cytoplasm
messages: The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped at one or both ends by the proteasome regulatory ATPase, PAN.
messages: The formation of the proteasomal ATPase PAN-20S proteasome complex, via the docking of the C-termini of PAN into the intersubunit pockets in the alpha-rings, triggers opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity.

368407:MEMAR RS09445
gene id: 368407:MEMAR_RS09445
uniprot id: A3CWU0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
messages: Cytoplasm
messages: Homodimer. Forms a heterotetramer with IscU, interacts with other sulfur acceptors.
messages: In Archaea the pyridoxal phosphate cofactor is not covalently bound to Lys but ligated by other amino acids.
messages: Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.

368407:MEMAR RS01225
gene id: 368407:MEMAR_RS01225
uniprot id: A3CS46
names: Function
names: Similarity
messages: Belongs to the Thz kinase family.
messages: Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).

368407:MEMAR RS03870
gene id: 368407:MEMAR_RS03870
uniprot id: A3CTM4
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

368407:MEMAR RS02980
gene id: 368407:MEMAR_RS02980
uniprot id: A3CT42
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MtrB family.
messages: Cell membrane
messages: Membrane
messages: Part of a complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step.
messages: The complex is composed of 8 subunits; MtrA, MtrB, MtrC, MtrD, MtrE, MtrF, MtrG and MtrH.

368407:MEMAR RS06285
gene id: 368407:MEMAR_RS06285
uniprot id: A3CV12
names: Subcellular Location Annotation
messages: Cytoplasm

368407:MEMAR RS09045
gene id: 368407:MEMAR_RS09045
uniprot id: A3CWL3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CofC family.
messages: Guanylyltransferase that catalyzes the activation of (2S)-2-phospholactate (2-PL) as (2S)-lactyl-2-diphospho-5'-guanosine, via the condensation of 2-PL with GTP. It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor.
messages: Homodimer.

368407:MEMAR RS03300
gene id: 368407:MEMAR_RS03300
uniprot id: A3CTA7
names: Subcellular Location Annotation
messages: Membrane

368407:MEMAR RS09250
gene id: 368407:MEMAR_RS09250
uniprot id: A3CWQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

368407:MEMAR RS09260
gene id: 368407:MEMAR_RS09260
uniprot id: A3CWQ6
names: Similarity
messages: Belongs to the bacterial solute-binding protein 1 family. WtpA subfamily.

368407:MEMAR RS05560
gene id: 368407:MEMAR_RS05560
uniprot id: A3CUL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

368407:MEMAR RS09655
gene id: 368407:MEMAR_RS09655
uniprot id: A3CWY3
names: Similarity
messages: Belongs to the eukaryotic/archaeal PrmC-related family.

368407:MEMAR RS04050
gene id: 368407:MEMAR_RS04050
uniprot id: A3CTR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CitM (TC 2.A.11) transporter family.
messages: Cell membrane
messages: Membrane

368407:MEMAR RS10910
gene id: 368407:MEMAR_RS10910
uniprot id: A3CXN3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

368407:MEMAR RS04950
gene id: 368407:MEMAR_RS04950
uniprot id: A3CU90
names: Similarity
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.

368407:MEMAR RS01175
gene id: 368407:MEMAR_RS01175
uniprot id: A3CS36
names: Similarity
messages: Belongs to the HerA family.

368407:MEMAR RS05025
gene id: 368407:MEMAR_RS05025
uniprot id: A3CUA5
names: Similarity
messages: Belongs to the HypE family.

368407:MEMAR RS11880
gene id: 368407:MEMAR_RS11880
uniprot id: A3CY81
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

368407:MEMAR RS03755
gene id: 368407:MEMAR_RS03755
uniprot id: A3CTK1
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.

368407:MEMAR RS01000
gene id: 368407:MEMAR_RS01000
uniprot id: A3CRZ9
names: Similarity
messages: Belongs to the radical SAM superfamily. KamA family.

368407:MEMAR RS09620
gene id: 368407:MEMAR_RS09620
uniprot id: A3CWX5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

368407:MEMAR RS00345
gene id: 368407:MEMAR_RS00345
uniprot id: A3CRK5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

368407:MEMAR RS10615
gene id: 368407:MEMAR_RS10615
uniprot id: A3CXH3
names: Cofactor
names: Similarity
messages: Belongs to the PdaD family.
messages: Binds 1 pyruvoyl group covalently per subunit.

368407:MEMAR RS00840
gene id: 368407:MEMAR_RS00840
uniprot id: A3CRV8
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

368407:MEMAR RS07315
gene id: 368407:MEMAR_RS07315
uniprot id: A3CVM3
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

368407:MEMAR RS01440
gene id: 368407:MEMAR_RS01440
uniprot id: A3CS85
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Forms part of the jaw domain.
messages: Part of the RNA polymerase complex.

368407:MEMAR RS08210
gene id: 368407:MEMAR_RS08210
uniprot id: A3CW53
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL43 family. Putative zinc-binding subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

368407:MEMAR RS07765
gene id: 368407:MEMAR_RS07765
uniprot id: A3CVW5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TOP6B family.
messages: Homodimer. Heterotetramer of two Top6A and two Top6B chains.
messages: Relaxes both positive and negative superturns and exhibits a strong decatenase activity.

368407:MEMAR RS06300
gene id: 368407:MEMAR_RS06300
uniprot id: A3CV16
names: Similarity
messages: Belongs to the archaeosine synthase type 1 family.

368407:MEMAR RS07700
gene id: 368407:MEMAR_RS07700
uniprot id: A3CVV1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 2 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

368407:MEMAR RS01795
gene id: 368407:MEMAR_RS01795
uniprot id: A3CSF8
names: Similarity
names: Subunit
messages: Belongs to the methyl-coenzyme M reductase beta subunit family.
messages: Hexamer of two alpha, two beta, and two gamma chains.
messages: MCR is a hexamer of two alpha, two beta, and two gamma chains, forming a dimer of heterotrimers.

368407:MEMAR RS06400
gene id: 368407:MEMAR_RS06400
uniprot id: A3CV35
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase-20S proteasome association which triggers gate opening, and supports translocation of unfolded substrates.
messages: Belongs to the AAA ATPase family.
messages: Consists of three main regions, an N-terminal coiled-coil domain that may assist in substrate recognition, an interdomain involved in PAN hexamerization, and a C-terminal ATPase domain of the AAA type.
messages: Cytoplasm
messages: Homohexamer. The hexameric complex has a two-ring architecture resembling a top hat that caps the 20S proteasome core at one or both ends. Upon ATP-binding, the C-terminus of PAN interacts with the alpha-rings of the proteasome core by binding to the intersubunit pockets.

368407:MEMAR RS08865
gene id: 368407:MEMAR_RS08865
uniprot id: A3CWI1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

368407:MEMAR RS01180
gene id: 368407:MEMAR_RS01180
uniprot id: A3CS37
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.
messages: Rubredoxin is a small nonheme, iron protein lacking acid-labile sulfide. Its single Fe, chelated to 4 Cys, functions as an electron acceptor and may also stabilize the conformation of the molecule.

368407:MEMAR RS01545
gene id: 368407:MEMAR_RS01545
uniprot id: A3CSA5
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

368407:MEMAR RS04595
gene id: 368407:MEMAR_RS04595
uniprot id: A3CU18
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

368407:MEMAR RS09025
gene id: 368407:MEMAR_RS09025
uniprot id: A3CWK9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

368407:MEMAR RS01450
gene id: 368407:MEMAR_RS01450
uniprot id: A3CS87
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Participates in transcription termination.

368407:MEMAR RS04415
gene id: 368407:MEMAR_RS04415
uniprot id: A3CTY4
names: Subcellular Location Annotation
messages: Membrane

368407:MEMAR RS02275
gene id: 368407:MEMAR_RS02275
uniprot id: A3CSQ2
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS8 family.
messages: Part of the 30S ribosomal subunit.

368407:MEMAR RS04690
gene id: 368407:MEMAR_RS04690
uniprot id: A3CU37
names: Subcellular Location Annotation
messages: Membrane

368407:MEMAR RS04165
gene id: 368407:MEMAR_RS04165
uniprot id: A3CTT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

368407:MEMAR RS01410
gene id: 368407:MEMAR_RS01410
uniprot id: A3CS80
names: Subcellular Location Annotation
messages: Membrane

368407:MEMAR RS02355
gene id: 368407:MEMAR_RS02355
uniprot id: A3CSR8
names: Similarity
messages: Belongs to the archaeal-type GPI family.

368407:MEMAR RS09030
gene id: 368407:MEMAR_RS09030
uniprot id: A3CWL0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

368407:MEMAR RS01815
gene id: 368407:MEMAR_RS01815
uniprot id: A3CSG3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis.

368407:MEMAR RS00055
gene id: 368407:MEMAR_RS00055
uniprot id: A3CRE7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

368407:MEMAR RS09335
gene id: 368407:MEMAR_RS09335
uniprot id: A3CWS0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

368407:MEMAR RS09660
gene id: 368407:MEMAR_RS09660
uniprot id: A3CWY4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

368407:MEMAR RS02040
gene id: 368407:MEMAR_RS02040
uniprot id: A3CSK8
names: Function
names: Similarity
messages: Belongs to the BPG-independent phosphoglycerate mutase family. A-PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

368407:MEMAR RS04155
gene id: 368407:MEMAR_RS04155
uniprot id: A3CTT1
names: Similarity
messages: Belongs to the universal ribosomal protein uL16 family.

368407:MEMAR RS02420
gene id: 368407:MEMAR_RS02420
uniprot id: A3CST1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Membrane

368407:MEMAR RS06940
gene id: 368407:MEMAR_RS06940
uniprot id: A3CVE5
names: Similarity
messages: Belongs to the UPF0147 family.

368407:MEMAR RS02080
gene id: 368407:MEMAR_RS02080
uniprot id: A3CSL5
names: Similarity
messages: In the N-terminal section; belongs to the zinc metallo-hydrolase group 3 family.

368407:MEMAR RS04860
gene id: 368407:MEMAR_RS04860
uniprot id: A3CU72
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

368407:MEMAR RS11375
gene id: 368407:MEMAR_RS11375
uniprot id: A3CXX7
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

368407:MEMAR RS05100
gene id: 368407:MEMAR_RS05100
uniprot id: A3CUC0
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

368407:MEMAR RS02405
gene id: 368407:MEMAR_RS02405
uniprot id: A3CSS8
names: Subcellular Location Annotation
messages: Membrane

368407:MEMAR RS03580
gene id: 368407:MEMAR_RS03580
uniprot id: A3CTG6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

368407:MEMAR RS01695
gene id: 368407:MEMAR_RS01695
uniprot id: A3CSD7
names: Subcellular Location Annotation
messages: Membrane

368407:MEMAR RS10730
gene id: 368407:MEMAR_RS10730
uniprot id: A3CXJ6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase IV family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin.
messages: Homodimer.

368407:MEMAR RS11585
gene id: 368407:MEMAR_RS11585
uniprot id: A3CY21
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA.
messages: Belongs to the TiaS family.
messages: Cytoplasm

368407:MEMAR RS11360
gene id: 368407:MEMAR_RS11360
uniprot id: A3CXX4
names: Function
names: Similarity
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.

368407:MEMAR RS01500
gene id: 368407:MEMAR_RS01500
uniprot id: A3CS83
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

368407:MEMAR RS00045
gene id: 368407:MEMAR_RS00045
uniprot id: A3CRE5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glutaminase PdxT/SNO family.
messages: Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
messages: In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer.

368407:MEMAR RS03555
gene id: 368407:MEMAR_RS03555
uniprot id: A3CTG1
names: Subcellular Location Annotation
messages: Membrane

368407:MEMAR RS10075
gene id: 368407:MEMAR_RS10075
uniprot id: A3CX65
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MntP (TC 9.B.29) family.
messages: Cell membrane
messages: Probably functions as a manganese efflux pump.

368407:MEMAR RS09715
gene id: 368407:MEMAR_RS09715
uniprot id: A3CWZ5
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL31 family.

368407:MEMAR RS09675
gene id: 368407:MEMAR_RS09675
uniprot id: A3CWY7
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL21 family.

368407:MEMAR RS08870
gene id: 368407:MEMAR_RS08870
uniprot id: A3CWI2
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

368407:MEMAR RS11255
gene id: 368407:MEMAR_RS11255
uniprot id: A3CXV2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

368407:MEMAR RS03445
gene id: 368407:MEMAR_RS03445
uniprot id: A3CTD9
names: Similarity
messages: Belongs to the SIS family. PHI subfamily.

368407:MEMAR RS11520
gene id: 368407:MEMAR_RS11520
uniprot id: A3CY07
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.

368407:MEMAR RS03155
gene id: 368407:MEMAR_RS03155
uniprot id: A3CT76
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

368407:MEMAR RS08885
gene id: 368407:MEMAR_RS08885
uniprot id: A3CWI6
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

368407:MEMAR RS10930
gene id: 368407:MEMAR_RS10930
uniprot id: A3CXN7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TYW1 family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Component of the wyosine derivatives biosynthesis pathway that catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine (imG-14) on guanosine-37 of tRNA(Phe).
messages: Cytoplasm
messages: Monomer.

368407:MEMAR RS02745
gene id: 368407:MEMAR_RS02745
uniprot id: A3CSZ5
names: Function
names: Similarity
messages: Belongs to the MTD family.
messages: Catalyzes the reversible reduction of methenyl-H(4)MPT(+) to methylene-H(4)MPT.

368407:MEMAR RS01550
gene id: 368407:MEMAR_RS01550
uniprot id: A3CSA6
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A single active site specifically recognizes both ATP and CTP and is responsible for their addition.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Archaeal CCA-adding enzyme subfamily.
messages: Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.
messages: Homodimer.

368407:MEMAR RS07645
gene id: 368407:MEMAR_RS07645
uniprot id: A3CVU0
names: Similarity
messages: Belongs to the AAA ATPase family. CDC48 subfamily.

368407:MEMAR RS08920
gene id: 368407:MEMAR_RS08920
uniprot id: A3CWJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 2 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm

368407:MEMAR RS03700
gene id: 368407:MEMAR_RS03700
uniprot id: A3CTJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 'phage' integrase family. XerA subfamily.
messages: Cytoplasm
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

368407:MEMAR RS02590
gene id: 368407:MEMAR_RS02590
uniprot id: A3CSW5
names: Domain
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the CobB/CbiA family.
messages: Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source. Involved in the biosynthesis of the unique nickel-containing tetrapyrrole coenzyme F430, the prosthetic group of methyl-coenzyme M reductase (MCR), which plays a key role in methanogenesis and anaerobic methane oxidation. Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of Ni-sirohydrochlorin, using L-glutamine or ammonia as the nitrogen source.
messages: Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP, and cobyrinate or Ni-sirohydrochlorin, and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.
messages: The a and c carboxylates of cobyrinate and Ni-sirohydrochlorin are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CbiA catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate.

368407:MEMAR RS08860
gene id: 368407:MEMAR_RS08860
uniprot id: A3CWI0
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL18 family.

368407:MEMAR RS08750
gene id: 368407:MEMAR_RS08750
uniprot id: A3CWF9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the diphthine synthase family.
messages: Homodimer.
messages: S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the trimethylation of the amino group of the modified target histidine residue in translation elongation factor 2 (EF-2), to form an intermediate called diphthine. The three successive methylation reactions represent the second step of diphthamide biosynthesis.

368407:MEMAR RS08900
gene id: 368407:MEMAR_RS08900
uniprot id: A3CWI9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the isopentenyl phosphate kinase family.
messages: Catalyzes the formation of isopentenyl diphosphate (IPP), the building block of all isoprenoids.
messages: Homodimer.

368407:MEMAR RS02835
gene id: 368407:MEMAR_RS02835
uniprot id: A3CT13
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

368407:MEMAR RS01715
gene id: 368407:MEMAR_RS01715
uniprot id: A3CSE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Cytoplasm

368407:MEMAR RS03225
gene id: 368407:MEMAR_RS03225
uniprot id: A3CT92
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

368407:MEMAR RS00975
gene id: 368407:MEMAR_RS00975
uniprot id: A3CRZ1
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

368407:MEMAR RS00290
gene id: 368407:MEMAR_RS00290
uniprot id: A3CRJ4
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

368407:MEMAR RS09755
gene id: 368407:MEMAR_RS09755
uniprot id: A3CX03
names: Subcellular Location Annotation
messages: Membrane

368407:MEMAR RS02765
gene id: 368407:MEMAR_RS02765
uniprot id: A3CSZ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: Binds to 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29.

368407:MEMAR RS10895
gene id: 368407:MEMAR_RS10895
uniprot id: A3CXN0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Part of the 30S ribosomal subunit.
messages: With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits.

368407:MEMAR RS07395
gene id: 368407:MEMAR_RS07395
uniprot id: A3CVP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0316 family.
messages: Cell membrane

368407:MEMAR RS09800
gene id: 368407:MEMAR_RS09800
uniprot id: A3CX12
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

368407:MEMAR RS09100
gene id: 368407:MEMAR_RS09100
uniprot id: A3CWM4
names: Function
names: Similarity
messages: Belongs to the group II decarboxylase family. MfnA subfamily.
messages: Catalyzes the decarboxylation of L-tyrosine to produce tyramine for methanofuran biosynthesis. Can also catalyze the decarboxylation of L-aspartate to produce beta-alanine for coenzyme A (CoA) biosynthesis.

368407:MEMAR RS00080
gene id: 368407:MEMAR_RS00080
uniprot id: A3CRF3
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Does not function as a glutathione-disulfide oxidoreductase in the presence of glutathione and glutathione reductase. Has low thioredoxin activity in vitro.

368407:MEMAR RS00915
gene id: 368407:MEMAR_RS00915
uniprot id: A3CRX5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

368407:MEMAR RS09720
gene id: 368407:MEMAR_RS09720
uniprot id: A3CWZ6
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL39 family.

368407:MEMAR RS08240
gene id: 368407:MEMAR_RS08240
uniprot id: A3CW59
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

368407:MEMAR RS09940
gene id: 368407:MEMAR_RS09940
uniprot id: A3CX39
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.

368407:MEMAR RS10735
gene id: 368407:MEMAR_RS10735
uniprot id: A3CXJ7
names: Similarity
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.

368407:MEMAR RS03675
gene id: 368407:MEMAR_RS03675
uniprot id: A3CTI5
names: Similarity
messages: Belongs to the acylphosphatase family.

368407:MEMAR RS09255
gene id: 368407:MEMAR_RS09255
uniprot id: A3CWQ5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

368407:MEMAR RS03860
gene id: 368407:MEMAR_RS03860
uniprot id: A3CTM2
names: Similarity
messages: Belongs to the helicase family. RAD3/XPD subfamily.

368407:MEMAR RS07925
gene id: 368407:MEMAR_RS07925
uniprot id: A3CVZ8
names: Similarity
messages: Belongs to the HerA family.

368407:MEMAR RS04115
gene id: 368407:MEMAR_RS04115
uniprot id: A3CTS3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

368407:MEMAR RS02205
gene id: 368407:MEMAR_RS02205
uniprot id: A3CSN9
names: Subcellular Location Annotation
messages: Membrane

368407:MEMAR RS04065
gene id: 368407:MEMAR_RS04065
uniprot id: A3CTR3
names: Similarity
messages: Belongs to the UPF0146 family.

368407:MEMAR RS03020
gene id: 368407:MEMAR_RS03020
uniprot id: A3CT50
names: Similarity
names: Subunit
messages: Belongs to the methyl-coenzyme M reductase beta subunit family.
messages: Hexamer of two alpha, two beta, and two gamma chains.
messages: MCR is a hexamer of two alpha, two beta, and two gamma chains, forming a dimer of heterotrimers.

368407:MEMAR RS04735
gene id: 368407:MEMAR_RS04735
uniprot id: A3CU48
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

368407:MEMAR RS05880
gene id: 368407:MEMAR_RS05880
uniprot id: A3CUS9
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
messages: Cytoplasm
messages: The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped at one or both ends by the proteasome regulatory ATPase, PAN.
messages: The formation of the proteasomal ATPase PAN-20S proteasome complex, via the docking of the C-termini of PAN into the intersubunit pockets in the alpha-rings, triggers opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity.

368407:MEMAR RS06815
gene id: 368407:MEMAR_RS06815
uniprot id: A3CVC0
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

368407:MEMAR RS06070
gene id: 368407:MEMAR_RS06070
uniprot id: A3CUW7
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

368407:MEMAR RS04915
gene id: 368407:MEMAR_RS04915
uniprot id: A3CU83
names: Cofactor
names: Similarity
messages: Belongs to the GARS family.
messages: Binds 2 magnesium or manganese ions per subunit.

368407:MEMAR RS04890
gene id: 368407:MEMAR_RS04890
uniprot id: A3CU78
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

368407:MEMAR RS08090
gene id: 368407:MEMAR_RS08090
uniprot id: A3CW28
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.
messages: Monomer.

368407:MEMAR RS07870
gene id: 368407:MEMAR_RS07870
uniprot id: A3CVY7
names: Subcellular Location Annotation
messages: Membrane

368407:MEMAR RS12020
gene id: 368407:MEMAR_RS12020
uniprot id: A3CYA6
names: Similarity
messages: Belongs to the UPF0251 family.

368407:MEMAR RS03765
gene id: 368407:MEMAR_RS03765
uniprot id: A3CTK3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

368407:MEMAR RS09145
gene id: 368407:MEMAR_RS09145
uniprot id: A3CWN4
names: Cofactor
names: Similarity
messages: Belongs to the UPF0313 family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

368407:MEMAR RS10105
gene id: 368407:MEMAR_RS10105
uniprot id: A3CX71
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycerol-1-phosphate dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea.
messages: Cytoplasm

368407:MEMAR RS07235
gene id: 368407:MEMAR_RS07235
uniprot id: A3CVK5
names: Similarity
messages: Belongs to the HerA family.

368407:MEMAR RS06220
gene id: 368407:MEMAR_RS06220
uniprot id: A3CUZ5
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.

368407:MEMAR RS08285
gene id: 368407:MEMAR_RS08285
uniprot id: A3CW68
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic CoaD family.
messages: Cytoplasm
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

368407:MEMAR RS08575
gene id: 368407:MEMAR_RS08575
uniprot id: A3CWC5
names: Subcellular Location Annotation
messages: Membrane

368407:MEMAR RS06720
gene id: 368407:MEMAR_RS06720
uniprot id: A3CVA0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

368407:MEMAR RS09175
gene id: 368407:MEMAR_RS09175
uniprot id: A3CWN9
names: Domain
names: Function
names: Similarity
messages: Belongs to the Nre family.
messages: Contains a predicted C4 metal binding domain at the N-terminus, which could be a zinc finger DNA binding domain.
messages: Involved in DNA damage repair.

368407:MEMAR RS03955
gene id: 368407:MEMAR_RS03955
uniprot id: A3CTP1
names: Subcellular Location Annotation
messages: Membrane

368407:MEMAR RS09385
gene id: 368407:MEMAR_RS09385
uniprot id: A3CWT0
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

368407:MEMAR RS03620
gene id: 368407:MEMAR_RS03620
uniprot id: A3CTH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

368407:MEMAR RS00375
gene id: 368407:MEMAR_RS00375
uniprot id: A3CRL1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

368407:MEMAR RS08095
gene id: 368407:MEMAR_RS08095
uniprot id: A3CW29
names: Similarity
messages: Belongs to the archease family.

368407:MEMAR RS02780
gene id: 368407:MEMAR_RS02780
uniprot id: A3CT02
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

368407:MEMAR RS09530
gene id: 368407:MEMAR_RS09530
uniprot id: A3CWV7
names: Function
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Rubredoxin is a small nonheme, iron protein lacking acid-labile sulfide. Its single Fe, chelated to 4 Cys, functions as an electron acceptor and may also stabilize the conformation of the molecule.

368407:MEMAR RS02845
gene id: 368407:MEMAR_RS02845
uniprot id: A3CT15
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL19 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

368407:MEMAR RS01495
gene id: 368407:MEMAR_RS01495
uniprot id: A3CS82
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: Part of the RNA polymerase complex.

368407:MEMAR RS09730
gene id: 368407:MEMAR_RS09730
uniprot id: A3CWZ8
names: Similarity
messages: Belongs to the PDCD5 family.

368407:MEMAR RS08300
gene id: 368407:MEMAR_RS08300
uniprot id: A3CW71
names: Function
names: Similarity
messages: Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).

368407:MEMAR RS06385
gene id: 368407:MEMAR_RS06385
uniprot id: A3CV32
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DeoC/FbaB aldolase family. ADHS subfamily.
messages: Catalyzes a transaldol reaction between 6-deoxy-5-ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids.
messages: Homodecamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

368407:MEMAR RS00545
gene id: 368407:MEMAR_RS00545
uniprot id: A3CRP6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the threonine synthase family. Cysteate synthase subfamily.
messages: Homotrimer.
messages: Specifically catalyzes the beta-elimination of phosphate from L-phosphoserine and the beta-addition of sulfite to the dehydroalanine intermediate to produce L-cysteate.

368407:MEMAR RS08850
gene id: 368407:MEMAR_RS08850
uniprot id: A3CWH8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit.

368407:MEMAR RS01975
gene id: 368407:MEMAR_RS01975
uniprot id: A3CSJ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

368407:MEMAR RS01520
gene id: 368407:MEMAR_RS01520
uniprot id: A3CS87
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Participates in transcription termination.

368407:MEMAR RS08830
gene id: 368407:MEMAR_RS08830
uniprot id: A3CWH5
names: Similarity
messages: Belongs to the deoxyhypusine synthase family.

368407:MEMAR RS07760
gene id: 368407:MEMAR_RS07760
uniprot id: A3CVW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm

368407:MEMAR RS07145
gene id: 368407:MEMAR_RS07145
uniprot id: A3CVI8
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS17 family.

368407:MEMAR RS09360
gene id: 368407:MEMAR_RS09360
uniprot id: A3CWS5
names: Activity Regulation
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.

368407:MEMAR RS06880
gene id: 368407:MEMAR_RS06880
uniprot id: A3CVD3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.
messages: Belongs to the ABC transporter superfamily. Energy-coupling factor EcfA family.
messages: Cell membrane
messages: Forms a stable energy-coupling factor (ECF) transporter complex composed of 2 membrane-embedded substrate-binding proteins (S component), 2 ATP-binding proteins (A component) and 2 transmembrane proteins (T component).

368407:MEMAR RS08940
gene id: 368407:MEMAR_RS08940
uniprot id: A3CWJ7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

368407:MEMAR RS02950
gene id: 368407:MEMAR_RS02950
uniprot id: A3CT36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

368407:MEMAR RS03615
gene id: 368407:MEMAR_RS03615
uniprot id: A3CTH3
names: Similarity
messages: Belongs to the UPF0305 family.

368407:MEMAR RS11465
gene id: 368407:MEMAR_RS11465
uniprot id: A3CXZ6
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

368407:MEMAR RS03480
gene id: 368407:MEMAR_RS03480
uniprot id: A3CTE6
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

368407:MEMAR RS04560
gene id: 368407:MEMAR_RS04560
uniprot id: A3CU11
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

368407:MEMAR RS01480
gene id: 368407:MEMAR_RS01480
uniprot id: A3CS80
names: Subcellular Location Annotation
messages: Membrane

368407:MEMAR RS01350
gene id: 368407:MEMAR_RS01350
uniprot id: A3CS69
names: Function
names: Similarity
messages: Belongs to the V-ATPase V0D/AC39 subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

368407:MEMAR RS09110
gene id: 368407:MEMAR_RS09110
uniprot id: A3CWM6
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

368407:MEMAR RS01135
gene id: 368407:MEMAR_RS01135
uniprot id: A3CS27
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

368407:MEMAR RS05015
gene id: 368407:MEMAR_RS05015
uniprot id: A3CUA3
names: Subcellular Location Annotation
messages: Membrane

368407:MEMAR RS09015
gene id: 368407:MEMAR_RS09015
uniprot id: A3CWK7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

368407:MEMAR RS02920
gene id: 368407:MEMAR_RS02920
uniprot id: A3CT30
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: Probably part of an ABC transporter complex. Responsible for energy coupling to the transport system.

368407:MEMAR RS03685
gene id: 368407:MEMAR_RS03685
uniprot id: A3CTI8
names: Similarity
messages: Belongs to the phosphohexose mutase family.

368407:MEMAR RS10490
gene id: 368407:MEMAR_RS10490
uniprot id: A3CXE7
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the archaeal DNA polymerase II family.
messages: Heterodimer of a large subunit and a small subunit.
messages: Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase (By similarity).
messages: This protein undergoes a protein self splicing that involves a post-translational excision of the intervening region (intein) followed by peptide ligation.

368407:MEMAR RS04295
gene id: 368407:MEMAR_RS04295
uniprot id: A3CTW0
names: Similarity
messages: Belongs to the Ahb/Nir family.

368407:MEMAR RS02810
gene id: 368407:MEMAR_RS02810
uniprot id: A3CT08
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: Located at the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

368407:MEMAR RS06795
gene id: 368407:MEMAR_RS06795
uniprot id: A3CVB5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
messages: Homodimer.

368407:MEMAR RS06900
gene id: 368407:MEMAR_RS06900
uniprot id: A3CVD7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

368407:MEMAR RS06805
gene id: 368407:MEMAR_RS06805
uniprot id: A3CVB7
names: Caution
names: Function
names: Similarity
messages: Belongs to the TBP family.
messages: General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

368407:MEMAR RS09495
gene id: 368407:MEMAR_RS09495
uniprot id: A3CWV0
names: Subcellular Location Annotation
messages: Membrane

368407:MEMAR RS05815
gene id: 368407:MEMAR_RS05815
uniprot id: A3CUR8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FwdB family.
messages: Catalyzes the reversible oxidation of CO(2) and methanofuran (MFR) to N-formylmethanofuran (CHO-MFR). This enzyme is oxygen-labile.
messages: This enzyme is composed of six subunits FwdA, FwdC, FwdD, FwdE, FwdF and FwdG.

368407:MEMAR RS08215
gene id: 368407:MEMAR_RS08215
uniprot id: A3CW54
names: Similarity
messages: Belongs to the SDO1/SBDS family.

368407:MEMAR RS05390
gene id: 368407:MEMAR_RS05390
uniprot id: A3CUH7
names: Similarity
messages: Belongs to the HsdR family.

368407:MEMAR RS12335
gene id: 368407:MEMAR_RS12335
uniprot id: A3CYH0
names: Similarity
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.

368407:MEMAR RS01335
gene id: 368407:MEMAR_RS01335
uniprot id: A3CS66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Membrane

368407:MEMAR RS07010
gene id: 368407:MEMAR_RS07010
uniprot id: A3CVG0
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

368407:MEMAR RS01775
gene id: 368407:MEMAR_RS01775
uniprot id: A3CSF3
names: Similarity
messages: Belongs to the FwdC/FmdC family.

368407:MEMAR RS00725
gene id: 368407:MEMAR_RS00725
uniprot id: A3CRT6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

368407:MEMAR RS08880
gene id: 368407:MEMAR_RS08880
uniprot id: A3CWI5
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

368407:MEMAR RS10215
gene id: 368407:MEMAR_RS10215
uniprot id: A3CX93
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the eIF-2B alpha/beta/delta subunits family. R15P isomerase subfamily.
messages: Catalyzes the isomerization of ribose 1,5-bisphosphate (R15P) to ribulose 1,5-bisphosphate (RuBP), the CO(2) acceptor and substrate for RubisCO. Functions in an archaeal AMP degradation pathway, together with AMP phosphorylase and RubisCO.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds via a cis-phosphoenolate intermediate.

368407:MEMAR RS10715
gene id: 368407:MEMAR_RS10715
uniprot id: A3CXJ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eIF-2-beta/eIF-5 family.
messages: Heterotrimer composed of an alpha, a beta and a gamma chain.
messages: eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA.

368407:MEMAR RS11250
gene id: 368407:MEMAR_RS11250
uniprot id: A3CXV1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

368407:MEMAR RS02805
gene id: 368407:MEMAR_RS02805
uniprot id: A3CT07
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L24e, part of which may contact the 16S rRNA in 2 intersubunit bridges.

368407:MEMAR RS02990
gene id: 368407:MEMAR_RS02990
uniprot id: A3CT44
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MtrD family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of a complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step.
messages: The complex is composed of 8 subunits; MtrA, MtrB, MtrC, MtrD, MtrE, MtrF, MtrG and MtrH.

368407:MEMAR RS04285
gene id: 368407:MEMAR_RS04285
uniprot id: A3CTV8
names: Similarity
messages: Belongs to the catalase family.

368407:MEMAR RS10590
gene id: 368407:MEMAR_RS10590
uniprot id: A3CXG8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CofD family.
messages: Catalyzes the transfer of the 2-phospholactate moiety from (2S)-lactyl-2-diphospho-5'-guanosine to 7,8-didemethyl-8-hydroxy-5-deazariboflavin (FO) with the formation of oxidized coenzyme F420-0 and GMP.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

368407:MEMAR RS02815
gene id: 368407:MEMAR_RS02815
uniprot id: A3CT09
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS4 family.

368407:MEMAR RS06475
gene id: 368407:MEMAR_RS06475
uniprot id: A3CV50
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

368407:MEMAR RS03820
gene id: 368407:MEMAR_RS03820
uniprot id: A3CTL4
names: Similarity
names: Subunit
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
messages: Homotetramer. Residues from neighboring subunits contribute catalytic and substrate-binding residues to each active site.

368407:MEMAR RS02625
gene id: 368407:MEMAR_RS02625
uniprot id: A3CSX1
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 2 subfamily.
messages: Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

368407:MEMAR RS01445
gene id: 368407:MEMAR_RS01445
uniprot id: A3CS86
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL30 family.

368407:MEMAR RS05385
gene id: 368407:MEMAR_RS05385
uniprot id: A3CUH6
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

368407:MEMAR RS00575
gene id: 368407:MEMAR_RS00575
uniprot id: A3CRQ3
names: Subcellular Location Annotation
messages: Cell membrane

368407:MEMAR RS00085
gene id: 368407:MEMAR_RS00085
uniprot id: A3CRF4
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Does not function as a glutathione-disulfide oxidoreductase in the presence of glutathione and glutathione reductase. Has low thioredoxin activity in vitro.

368407:MEMAR RS08450
gene id: 368407:MEMAR_RS08450
uniprot id: A3CW98
names: Similarity
messages: Belongs to the Nth/MutY family.

368407:MEMAR RS04605
gene id: 368407:MEMAR_RS04605
uniprot id: A3CU20
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic release factor 1 family. Pelota subfamily.
messages: Cytoplasm
messages: May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA. May play a role in the release non-functional ribosomes and degradation of damaged mRNAs. Has endoribonuclease activity.
messages: Monomer.
messages: The N-terminal domain has the RNA-binding Sm fold. It harbors the endoribonuclease activity.

368407:MEMAR RS12195
gene id: 368407:MEMAR_RS12195
uniprot id: A3CYE2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Aminocarboxypropyltransferase that catalyzes the aminocarboxypropyl transfer on pseudouridine corresponding to position 914 in M.jannaschii 16S rRNA. It constitutes the last step in biosynthesis of the hypermodified N1-methyl-N3-(3-amino-3-carboxypropyl) pseudouridine (m1acp3-Psi).
messages: Belongs to the TDD superfamily. TSR3 family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

368407:MEMAR RS01285
gene id: 368407:MEMAR_RS01285
uniprot id: A3CS56
names: Similarity
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.

368407:MEMAR RS06205
gene id: 368407:MEMAR_RS06205
uniprot id: A3CUZ2
names: Similarity
messages: Belongs to the glycogen phosphorylase family.

368407:MEMAR RS12065
gene id: 368407:MEMAR_RS12065
uniprot id: A3CYB5
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

368407:MEMAR RS00780
gene id: 368407:MEMAR_RS00780
uniprot id: A3CRU7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. Prx6 subfamily.
messages: Cytoplasm
messages: Homodecamer. Pentamer of dimers that assemble into a ring structure.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. Although the primary sequence of this enzyme is similar to those of the 1-Cys Prx6 enzymes, its catalytic properties resemble those of the typical 2-Cys Prxs and C(R) is provided by the other dimeric subunit to form an intersubunit disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

368407:MEMAR RS04640
gene id: 368407:MEMAR_RS04640
uniprot id: A3CU27
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

368407:MEMAR RS03035
gene id: 368407:MEMAR_RS03035
uniprot id: A3CT53
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FwdB family.
messages: Catalyzes the reversible oxidation of CO(2) and methanofuran (MFR) to N-formylmethanofuran (CHO-MFR). This enzyme is oxygen-labile.
messages: This enzyme is composed of six subunits FwdA, FwdC, FwdD, FwdE, FwdF and FwdG.

368407:MEMAR RS01505
gene id: 368407:MEMAR_RS01505
uniprot id: A3CS84
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds at least 2 Zn(2+) per subunit.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Forms the clamp head domain.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

368407:MEMAR RS00270
gene id: 368407:MEMAR_RS00270
uniprot id: A3CRJ0
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

368407:MEMAR RS00015
gene id: 368407:MEMAR_RS00015
uniprot id: A3CRD8
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

368407:MEMAR RS06850
gene id: 368407:MEMAR_RS06850
uniprot id: A3CVC8
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruD family.
messages: Could be responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.

368407:MEMAR RS03770
gene id: 368407:MEMAR_RS03770
uniprot id: A3CTK4
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

368407:MEMAR RS10020
gene id: 368407:MEMAR_RS10020
uniprot id: A3CX54
names: Similarity
messages: Belongs to the glutamate synthase family.

368407:MEMAR RS02235
gene id: 368407:MEMAR_RS02235
uniprot id: A3CSP4
names: Function
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2.

368407:MEMAR RS04750
gene id: 368407:MEMAR_RS04750
uniprot id: A3CU51
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.

368407:MEMAR RS04780
gene id: 368407:MEMAR_RS04780
uniprot id: A3CU57
names: Similarity
messages: Belongs to the myo-inositol 1-phosphate synthase family.

368407:MEMAR RS03440
gene id: 368407:MEMAR_RS03440
uniprot id: A3CTD8
names: Similarity
messages: Belongs to the UPF0285 family.

368407:MEMAR RS09535
gene id: 368407:MEMAR_RS09535
uniprot id: A3CWV8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endonuclease V family.
messages: Cytoplasm
messages: DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA.

368407:MEMAR RS03985
gene id: 368407:MEMAR_RS03985
uniprot id: A3CTP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Membrane

368407:MEMAR RS09520
gene id: 368407:MEMAR_RS09520
uniprot id: A3CWV5
names: Subcellular Location Annotation
messages: Membrane

368407:MEMAR RS11200
gene id: 368407:MEMAR_RS11200
uniprot id: A3CXU1
names: Similarity
messages: Belongs to the UPF0237 family.

368407:MEMAR RS01565
gene id: 368407:MEMAR_RS01565
uniprot id: A3CSB0
names: Subcellular Location Annotation
messages: Membrane

368407:MEMAR RS06915
gene id: 368407:MEMAR_RS06915
uniprot id: A3CVE0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

368407:MEMAR RS07275
gene id: 368407:MEMAR_RS07275
uniprot id: A3CVL4
names: Similarity
messages: Belongs to the UPF0175 family.

368407:MEMAR RS07165
gene id: 368407:MEMAR_RS07165
uniprot id: A3CVJ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PCNA family.
messages: Homotrimer. The subunits circularize to form a toroid; DNA passes through its center. Replication factor C (RFC) is required to load the toroid on the DNA.
messages: Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication.

368407:MEMAR RS02865
gene id: 368407:MEMAR_RS02865
uniprot id: A3CT19
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

368407:MEMAR RS09615
gene id: 368407:MEMAR_RS09615
uniprot id: A3CWX4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 2 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

368407:MEMAR RS06990
gene id: 368407:MEMAR_RS06990
uniprot id: A3CVF6
names: Function
messages: Polynucleotide kinase that can phosphorylate the 5'-hydroxyl groups of both single-stranded RNA (ssRNA) and single-stranded DNA (ssDNA). Exhibits a strong preference for ssRNA.

368407:MEMAR RS04070
gene id: 368407:MEMAR_RS04070
uniprot id: A3CTR4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the activator 1 small subunits family. RfcL subfamily.
messages: Heteromultimer composed of small subunits (RfcS) and large subunits (RfcL).
messages: Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA.

368407:MEMAR RS00020
gene id: 368407:MEMAR_RS00020
uniprot id: A3CRE0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

368407:MEMAR RS08515
gene id: 368407:MEMAR_RS08515
uniprot id: A3CWB1
names: Domain
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the CobB/CbiA family.
messages: Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source. Involved in the biosynthesis of the unique nickel-containing tetrapyrrole coenzyme F430, the prosthetic group of methyl-coenzyme M reductase (MCR), which plays a key role in methanogenesis and anaerobic methane oxidation. Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of Ni-sirohydrochlorin, using L-glutamine or ammonia as the nitrogen source.
messages: Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP, and cobyrinate or Ni-sirohydrochlorin, and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.
messages: The a and c carboxylates of cobyrinate and Ni-sirohydrochlorin are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CbiA catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate.

368407:MEMAR RS04880
gene id: 368407:MEMAR_RS04880
uniprot id: A3CU76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

368407:MEMAR RS03840
gene id: 368407:MEMAR_RS03840
uniprot id: A3CTL8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mediates influx of magnesium ions.
messages: Membrane

368407:MEMAR RS06240
gene id: 368407:MEMAR_RS06240
uniprot id: A3CUZ9
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

368407:MEMAR RS10570
gene id: 368407:MEMAR_RS10570
uniprot id: A3CXG3
names: Caution
names: Function
names: Similarity
messages: Belongs to the UbiX/PAD1 family.
messages: Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

368407:MEMAR RS01890
gene id: 368407:MEMAR_RS01890
uniprot id: A3CSH8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

368407:MEMAR RS06685
gene id: 368407:MEMAR_RS06685
uniprot id: A3CV93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

368407:MEMAR RS01065
gene id: 368407:MEMAR_RS01065
uniprot id: A3CS12
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

368407:MEMAR RS08890
gene id: 368407:MEMAR_RS08890
uniprot id: A3CWI7
names: Similarity
messages: Belongs to the MEMO1 family.

368407:MEMAR RS03055
gene id: 368407:MEMAR_RS03055
uniprot id: A3CT57
names: Similarity
messages: Belongs to the HdrB family.

368407:MEMAR RS11105
gene id: 368407:MEMAR_RS11105
uniprot id: A3CXS2
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL40 family.

368407:MEMAR RS09690
gene id: 368407:MEMAR_RS09690
uniprot id: A3CWZ0
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. Archaeal SRP consists of a 7S RNA molecule of 300 nucleotides and two protein subunits: SRP54 and SRP19.

368407:MEMAR RS09695
gene id: 368407:MEMAR_RS09695
uniprot id: A3CWZ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

368407:MEMAR RS10690
gene id: 368407:MEMAR_RS10690
uniprot id: A3CXI8
names: Subcellular Location Annotation
messages: Membrane

368407:MEMAR RS04010
gene id: 368407:MEMAR_RS04010
uniprot id: A3CTQ2
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the L-aspartate dehydrogenase family.
messages: Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate.
messages: The iminoaspartate product is unstable in aqueous solution and can decompose to oxaloacetate and ammonia.

368407:MEMAR RS11575
gene id: 368407:MEMAR_RS11575
uniprot id: A3CY19
names: Similarity
messages: Belongs to the TCP-1 chaperonin family.

368407:MEMAR RS03760
gene id: 368407:MEMAR_RS03760
uniprot id: A3CTK2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GGGP/HepGP synthase family. Group I subfamily.
messages: Cytoplasm
messages: Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids.

368407:MEMAR RS01255
gene id: 368407:MEMAR_RS01255
uniprot id: A3CS52
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

368407:MEMAR RS04555
gene id: 368407:MEMAR_RS04555
uniprot id: A3CU10
names: Subcellular Location Annotation
messages: Cytoplasm

368407:MEMAR RS09480
gene id: 368407:MEMAR_RS09480
uniprot id: A3CWU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal histone HMF family.
messages: Chromosome
messages: Cytoplasm

368407:MEMAR RS02575
gene id: 368407:MEMAR_RS02575
uniprot id: A3CSW2
names: Subcellular Location Annotation
messages: Membrane

368407:MEMAR RS10860
gene id: 368407:MEMAR_RS10860
uniprot id: A3CXM3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

368407:MEMAR RS02285
gene id: 368407:MEMAR_RS02285
uniprot id: A3CSQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SRP19 family.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds directly to 7S RNA and mediates binding of the 54 kDa subunit of the SRP.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. Archaeal SRP consists of a 7S RNA molecule of 300 nucleotides and two protein subunits: SRP54 and SRP19.

368407:MEMAR RS02570
gene id: 368407:MEMAR_RS02570
uniprot id: A3CSW1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane
messages: Part of an ABC transporter complex. Responsible for energy coupling to the transport system.
messages: Probably part of an ABC transporter complex. Responsible for energy coupling to the transport system.

368407:MEMAR RS08260
gene id: 368407:MEMAR_RS08260
uniprot id: A3CW63
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAC-alpha family.
messages: Contacts the emerging nascent chain on the ribosome.
messages: Homodimer. Interacts with the ribosome. Binds ribosomal RNA.

368407:MEMAR RS00035
gene id: 368407:MEMAR_RS00035
uniprot id: A3CRE3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

368407:MEMAR RS10320
gene id: 368407:MEMAR_RS10320
uniprot id: A3CXB6
names: Similarity
messages: Belongs to the peptidase M24B family.

368407:MEMAR RS11650
gene id: 368407:MEMAR_RS11650
uniprot id: A3CY34
names: Similarity
messages: Belongs to the thiolase-like superfamily. UPF0219 family.

368407:MEMAR RS00900
gene id: 368407:MEMAR_RS00900
uniprot id: A3CRX2
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.

368407:MEMAR RS08730
gene id: 368407:MEMAR_RS08730
uniprot id: A3CWF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA-PH family.
messages: Cytoplasm

368407:MEMAR RS00040
gene id: 368407:MEMAR_RS00040
uniprot id: A3CRE4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PdxS/SNZ family.
messages: Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
messages: In the presence of PdxT, forms a dodecamer of heterodimers.

368407:MEMAR RS03160
gene id: 368407:MEMAR_RS03160
uniprot id: A3CT77
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 2 subfamily.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

368407:MEMAR RS06920
gene id: 368407:MEMAR_RS06920
uniprot id: A3CVE1
names: Subcellular Location Annotation
messages: Membrane

368407:MEMAR RS08965
gene id: 368407:MEMAR_RS08965
uniprot id: A3CWK2
names: Subcellular Location Annotation
messages: Membrane

368407:MEMAR RS08115
gene id: 368407:MEMAR_RS08115
uniprot id: A3CW33
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Involved in protein export.
messages: Membrane
messages: Part of the protein translocation apparatus. Forms a complex with SecF.

368407:MEMAR RS05310
gene id: 368407:MEMAR_RS05310
uniprot id: A3CUG3
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

368407:MEMAR RS10370
gene id: 368407:MEMAR_RS10370
uniprot id: A3CXC5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

368407:MEMAR RS03715
gene id: 368407:MEMAR_RS03715
uniprot id: A3CTJ4
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 2 family.

368407:MEMAR RS00910
gene id: 368407:MEMAR_RS00910
uniprot id: A3CRX4
names: Subcellular Location Annotation
messages: Membrane

368407:MEMAR RS01810
gene id: 368407:MEMAR_RS01810
uniprot id: A3CSG1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the methyl-coenzyme M reductase alpha subunit family.
messages: Binds 2 coenzyme F430 non-covalently per MCR complex. Coenzyme F430 is a yellow nickel porphinoid. Methyl-coenzyme-M reductase is activated when the enzyme-bound coenzyme F430 is reduced to the Ni(I) oxidation state.
messages: Component of the methyl-coenzyme M reductase (MCR) I that catalyzes the reductive cleavage of methyl-coenzyme M (CoM-S-CH3 or 2-(methylthio)ethanesulfonate) using coenzyme B (CoB or 7-mercaptoheptanoylthreonine phosphate) as reductant which results in the production of methane and the mixed heterodisulfide of CoB and CoM (CoM-S-S-CoB). This is the final step in methanogenesis.
messages: Hexamer of two alpha, two beta, and two gamma chains.
messages: MCR is a hexamer of two alpha, two beta, and two gamma chains, forming a dimer of heterotrimers.

368407:MEMAR RS02785
gene id: 368407:MEMAR_RS02785
uniprot id: A3CT03
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head.
messages: Part of the 30S ribosomal subunit.

368407:MEMAR RS01280
gene id: 368407:MEMAR_RS01280
uniprot id: A3CS55
names: Similarity
messages: Belongs to the TCP-1 chaperonin family.

368407:MEMAR RS01085
gene id: 368407:MEMAR_RS01085
uniprot id: A3CS17
names: Similarity
messages: Belongs to the ZPR1 family.

368407:MEMAR RS10365
gene id: 368407:MEMAR_RS10365
uniprot id: A3CXC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

368407:MEMAR RS06485
gene id: 368407:MEMAR_RS06485
uniprot id: A3CV52
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

368407:MEMAR RS00215
gene id: 368407:MEMAR_RS00215
uniprot id: A3CRI0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase delta/II small subunit family.
messages: Heterodimer of a large subunit and a small subunit.
messages: Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase.

368407:MEMAR RS09465
gene id: 368407:MEMAR_RS09465
uniprot id: A3CWU4
names: Function
names: Similarity
messages: Belongs to the eukaryotic RecA-like protein family.
messages: Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules.

368407:MEMAR RS08520
gene id: 368407:MEMAR_RS08520
uniprot id: A3CWB2
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

368407:MEMAR RS12345
gene id: 368407:MEMAR_RS12345
uniprot id: A3CYH2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. Hel308 subfamily.
messages: DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks.
messages: Monomer.

368407:MEMAR RS01425
gene id: 368407:MEMAR_RS01425
uniprot id: A3CS82
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: Part of the RNA polymerase complex.

368407:MEMAR RS06885
gene id: 368407:MEMAR_RS06885
uniprot id: A3CVD4
names: Subcellular Location Annotation
messages: Membrane

368407:MEMAR RS07170
gene id: 368407:MEMAR_RS07170
uniprot id: A3CVJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
messages: Cytoplasm
messages: Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.

368407:MEMAR RS04205
gene id: 368407:MEMAR_RS04205
uniprot id: A3CTU2
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

368407:MEMAR RS06740
gene id: 368407:MEMAR_RS06740
uniprot id: A3CVA4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Archaeal flagellum
messages: Belongs to the archaeal flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of archaeal flagella.

368407:MEMAR RS01915
gene id: 368407:MEMAR_RS01915
uniprot id: A3CSI3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

368407:MEMAR RS01985
gene id: 368407:MEMAR_RS01985
uniprot id: A3CSJ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the 50S ribosomal subunit. Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Forms a heptameric L10(L12)2(L12)2(L12)2 complex, where L10 forms an elongated spine to which the L12 dimers bind in a sequential fashion.

368407:MEMAR RS11000
gene id: 368407:MEMAR_RS11000
uniprot id: A3CXQ1
names: Similarity
messages: Belongs to the phosphohexose mutase family.

368407:MEMAR RS03165
gene id: 368407:MEMAR_RS03165
uniprot id: A3CT78
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

368407:MEMAR RS11995
gene id: 368407:MEMAR_RS11995
uniprot id: A3CYA2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
messages: Cytoplasm
messages: Homodimer. Forms a heterotetramer with IscU, interacts with other sulfur acceptors.
messages: In Archaea the pyridoxal phosphate cofactor is not covalently bound to Lys but ligated by other amino acids.
messages: Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.

368407:MEMAR RS09215
gene id: 368407:MEMAR_RS09215
uniprot id: A3CWP6
names: Similarity
messages: Belongs to the glycosyltransferase 2 family.

368407:MEMAR RS03410
gene id: 368407:MEMAR_RS03410
uniprot id: A3CTD2
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

368407:MEMAR RS04185
gene id: 368407:MEMAR_RS04185
uniprot id: A3CTT7
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate.
messages: Belongs to the GatB/GatE family. GatE subfamily.
messages: Heterodimer of GatD and GatE.

368407:MEMAR RS03505
gene id: 368407:MEMAR_RS03505
uniprot id: A3CTF1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

368407:MEMAR RS02240
gene id: 368407:MEMAR_RS02240
uniprot id: A3CSP5
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS6 family.

368407:MEMAR RS04825
gene id: 368407:MEMAR_RS04825
uniprot id: A3CU65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm

368407:MEMAR RS09545
gene id: 368407:MEMAR_RS09545
uniprot id: A3CWW0
names: Similarity
messages: Belongs to the phosphoribulokinase family.

368407:MEMAR RS05080
gene id: 368407:MEMAR_RS05080
uniprot id: A3CUB7
names: Cofactor
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

368407:MEMAR RS08845
gene id: 368407:MEMAR_RS08845
uniprot id: A3CWH7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

368407:MEMAR RS03590
gene id: 368407:MEMAR_RS03590
uniprot id: A3CTG8
names: Similarity
messages: Belongs to the UPF0284 family.

368407:MEMAR RS07175
gene id: 368407:MEMAR_RS07175
uniprot id: A3CVJ4
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

368407:MEMAR RS07190
gene id: 368407:MEMAR_RS07190
uniprot id: A3CVJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

368407:MEMAR RS11275
gene id: 368407:MEMAR_RS11275
uniprot id: A3CXV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

368407:MEMAR RS05285
gene id: 368407:MEMAR_RS05285
uniprot id: A3CUF8
names: Similarity
messages: Belongs to the peptidase S33 family.

368407:MEMAR RS04835
gene id: 368407:MEMAR_RS04835
uniprot id: A3CU67
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

368407:MEMAR RS05000
gene id: 368407:MEMAR_RS05000
uniprot id: A3CUA0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the archaeal DnaG primase family.
messages: Binds two Mg(2+) per subunit.
messages: Forms a ternary complex with MCM helicase and DNA.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

368407:MEMAR RS03075
gene id: 368407:MEMAR_RS03075
uniprot id: A3CT61
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FTR family.
messages: Catalyzes the reversible transfer of a formyl group from formylmethanofuran (formyl-MFR) to tetrahydromethanopterin (H(4)MPT) to produce 5-formyl tetrahydromethanopterin (5-formyl-H(4)MPT) and methanofuran (MFR).
messages: Cytoplasm
messages: Homotetramer.

368407:MEMAR RS00360
gene id: 368407:MEMAR_RS00360
uniprot id: A3CRK8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.

368407:MEMAR RS02760
gene id: 368407:MEMAR_RS02760
uniprot id: A3CSZ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

368407:MEMAR RS04425
gene id: 368407:MEMAR_RS04425
uniprot id: A3CTY6
names: Similarity
messages: Belongs to the DNA glycosylase MPG family.

368407:MEMAR RS05030
gene id: 368407:MEMAR_RS05030
uniprot id: A3CUA6
names: Function
names: Similarity
messages: Belongs to the HypA/HybF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.

368407:MEMAR RS09130
gene id: 368407:MEMAR_RS09130
uniprot id: A3CWN1
names: Similarity
messages: Belongs to the AHA1 family.

368407:MEMAR RS05225
gene id: 368407:MEMAR_RS05225
uniprot id: A3CUE5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

368407:MEMAR RS06480
gene id: 368407:MEMAR_RS06480
uniprot id: A3CV51
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

368407:MEMAR RS06065
gene id: 368407:MEMAR_RS06065
uniprot id: A3CUW6
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. PoK subfamily.
messages: Phosphorylates (R)-pantoate to form (R)-4-phosphopantoate in the CoA biosynthesis pathway.

368407:MEMAR RS11245
gene id: 368407:MEMAR_RS11245
uniprot id: A3CXV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Membrane

368407:MEMAR RS09560
gene id: 368407:MEMAR_RS09560
uniprot id: A3CWW3
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the NifH/BchL/ChlL family.
messages: Binds 1 [4Fe-4S] cluster per dimer.
messages: Homodimer.
messages: The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein.
messages: The reversible ADP-ribosylation of Arg-98 inactivates the nitrogenase reductase and regulates nitrogenase activity.

368407:MEMAR RS02860
gene id: 368407:MEMAR_RS02860
uniprot id: A3CT18
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

368407:MEMAR RS03010
gene id: 368407:MEMAR_RS03010
uniprot id: A3CT48
names: Subunit
messages: MCR is composed of three subunits: alpha, beta, and gamma. The function of proteins C and D is not known.

368407:MEMAR RS02335
gene id: 368407:MEMAR_RS02335
uniprot id: A3CSR3
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

368407:MEMAR RS10655
gene id: 368407:MEMAR_RS10655
uniprot id: A3CXI1
names: Similarity
messages: Belongs to the LarC family.

368407:MEMAR RS08915
gene id: 368407:MEMAR_RS08915
uniprot id: A3CWJ2
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

368407:MEMAR RS07655
gene id: 368407:MEMAR_RS07655
uniprot id: A3CVU2
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FBP aldolase/phosphatase family.
messages: Catalyzes two subsequent steps in gluconeogenesis: the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3-phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P).
messages: Consists of a single catalytic domain, but remodels its active-site architecture via a large structural change to exhibit dual activities.
messages: Homooctamer; dimer of tetramers.

368407:MEMAR RS01785
gene id: 368407:MEMAR_RS01785
uniprot id: A3CSF5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FwdB family.
messages: Catalyzes the reversible oxidation of CO(2) and methanofuran (MFR) to N-formylmethanofuran (CHO-MFR). This enzyme is oxygen-labile.
messages: This enzyme is composed of six subunits FwdA, FwdC, FwdD, FwdE, FwdF and FwdG.

368407:MEMAR RS07140
gene id: 368407:MEMAR_RS07140
uniprot id: A3CVI7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

368407:MEMAR RS00735
gene id: 368407:MEMAR_RS00735
uniprot id: A3CRT8
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

368407:MEMAR RS02480
gene id: 368407:MEMAR_RS02480
uniprot id: A3CSU3
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

368407:MEMAR RS06035
gene id: 368407:MEMAR_RS06035
uniprot id: A3CUW0
names: Similarity
messages: Belongs to the HepT RNase toxin family.

368407:MEMAR RS05595
gene id: 368407:MEMAR_RS05595
uniprot id: A3CUM2
names: Similarity
messages: Belongs to the HypD family.

368407:MEMAR RS01570
gene id: 368407:MEMAR_RS01570
uniprot id: A3CSB1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

368407:MEMAR RS09430
gene id: 368407:MEMAR_RS09430
uniprot id: A3CWT7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for formate dehydrogenase (FDH) activity.

368407:MEMAR RS04040
gene id: 368407:MEMAR_RS04040
uniprot id: A3CTQ8
names: Similarity
messages: Belongs to the alpha-acetolactate decarboxylase family.

368407:MEMAR RS09050
gene id: 368407:MEMAR_RS09050
uniprot id: A3CWL4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. CofG family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated synthesis of 7,8-didemethyl-8-hydroxy-5-deazariboflavin from 5-amino-5-(4-hydroxybenzyl)-6-(D-ribitylimino)-5,6-dihydrouracil.
messages: Consists of two subunits, CofG and CofH.

368407:MEMAR RS08355
gene id: 368407:MEMAR_RS08355
uniprot id: A3CW79
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

368407:MEMAR RS01150
gene id: 368407:MEMAR_RS01150
uniprot id: A3CS31
names: Similarity
messages: Belongs to the carbamate kinase family.

368407:MEMAR RS03965
gene id: 368407:MEMAR_RS03965
uniprot id: A3CTP3
names: Subcellular Location Annotation
messages: Membrane

368407:MEMAR RS10890
gene id: 368407:MEMAR_RS10890
uniprot id: A3CXM9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center.
messages: Part of the 30S ribosomal subunit.

368407:MEMAR RS02685
gene id: 368407:MEMAR_RS02685
uniprot id: A3CSY2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Archaeal-type ThyA subfamily.
messages: Cytoplasm
messages: May catalyze the biosynthesis of dTMP using an unknown cosubstrate.
messages: Monomer.

368407:MEMAR RS00070
gene id: 368407:MEMAR_RS00070
uniprot id: A3CRF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

368407:MEMAR RS03895
gene id: 368407:MEMAR_RS03895
uniprot id: A3CTN0
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

368407:MEMAR RS12265
gene id: 368407:MEMAR_RS12265
uniprot id: A3CYF6
names: Similarity
messages: Belongs to the IMPACT family.

368407:MEMAR RS01205
gene id: 368407:MEMAR_RS01205
uniprot id: A3CS42
names: Similarity
messages: Belongs to the tRNA methyltransferase O family.

368407:MEMAR RS05335
gene id: 368407:MEMAR_RS05335
uniprot id: A3CUG8
names: Function
names: Similarity
messages: Catalyzes the condensation of formaldehyde with tetrahydromethanopterin (H(4)MPT) to 5,10-methylenetetrahydromethanopterin.
messages: Catalyzes the reversible formation of ribulose-5-phosphate and formaldehyde from 3-hexulose-6-phosphate.
messages: In the C-terminal section; belongs to the HPS/KGPDC family. HPS subfamily.
messages: In the N-terminal section; belongs to the formaldehyde-activating enzyme family.

368407:MEMAR RS00790
gene id: 368407:MEMAR_RS00790
uniprot id: A3CRU9
names: Cofactor
messages: Binds 2 irons ions per subunit via 4 cysteine residues per iron.

368407:MEMAR RS07435
gene id: 368407:MEMAR_RS07435
uniprot id: A3CVP8
names: Similarity
messages: Belongs to the UPF0280 family.

368407:MEMAR RS09855
gene id: 368407:MEMAR_RS09855
uniprot id: A3CX23
names: Similarity
messages: Belongs to the SUI1 family.

368407:MEMAR RS10380
gene id: 368407:MEMAR_RS10380
uniprot id: A3CXC7
names: Subcellular Location Annotation
messages: Membrane

368407:MEMAR RS10205
gene id: 368407:MEMAR_RS10205
uniprot id: A3CX91
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

368407:MEMAR RS04840
gene id: 368407:MEMAR_RS04840
uniprot id: A3CU68
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.

368407:MEMAR RS07030
gene id: 368407:MEMAR_RS07030
uniprot id: A3CVG4
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

368407:MEMAR RS10530
gene id: 368407:MEMAR_RS10530
uniprot id: A3CXF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CitM (TC 2.A.11) transporter family.
messages: Cell membrane
messages: Membrane

368407:MEMAR RS05105
gene id: 368407:MEMAR_RS05105
uniprot id: A3CUC1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane
messages: Potential transporter for phosphate.

368407:MEMAR RS02820
gene id: 368407:MEMAR_RS02820
uniprot id: A3CT10
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; contacts the 5S rRNA and probably tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. May contact the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

368407:MEMAR RS08755
gene id: 368407:MEMAR_RS08755
uniprot id: A3CWG0
names: Subcellular Location Annotation
messages: Membrane

368407:MEMAR RS04090
gene id: 368407:MEMAR_RS04090
uniprot id: A3CTR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

368407:MEMAR RS02190
gene id: 368407:MEMAR_RS02190
uniprot id: A3CSN6
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

368407:MEMAR RS11025
gene id: 368407:MEMAR_RS11025
uniprot id: A3CXQ6
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

368407:MEMAR RS01030
gene id: 368407:MEMAR_RS01030
uniprot id: A3CS06
names: Similarity
messages: Belongs to the aspartokinase family.

368407:MEMAR RS10310
gene id: 368407:MEMAR_RS10310
uniprot id: A3CXB4
names: Similarity
messages: Belongs to the AAA ATPase family.

368407:MEMAR RS11755
gene id: 368407:MEMAR_RS11755
uniprot id: A3CY55
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

368407:MEMAR RS10790
gene id: 368407:MEMAR_RS10790
uniprot id: A3CXK9
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

368407:MEMAR RS12110
gene id: 368407:MEMAR_RS12110
uniprot id: A3CYC5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ferredoxin thioredoxin reductase beta subunit family.
messages: Catalytic subunit of the ferredoxin-thioredoxin reductase (FTR), which catalyzes the two-electron reduction of thioredoxins by the electrons provided by reduced ferredoxin.
messages: Heterodimer of subunit A (variable subunit) and subunit B (catalytic subunit). Heterodimeric FTR forms a complex with ferredoxin and thioredoxin.

368407:MEMAR RS06835
gene id: 368407:MEMAR_RS06835
uniprot id: A3CVC5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

368407:MEMAR RS02775
gene id: 368407:MEMAR_RS02775
uniprot id: A3CT01
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

368407:MEMAR RS09295
gene id: 368407:MEMAR_RS09295
uniprot id: A3CWR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

368407:MEMAR RS03775
gene id: 368407:MEMAR_RS03775
uniprot id: A3CTK5
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

368407:MEMAR RS11295
gene id: 368407:MEMAR_RS11295
uniprot id: A3CXW1
names: Similarity
messages: Belongs to the glutamine synthetase family.

368407:MEMAR RS00005
gene id: 368407:MEMAR_RS00005
uniprot id: A3CRD6
names: Function
names: Similarity
messages: Belongs to the CDC6/cdc18 family.
messages: Involved in regulation of DNA replication.

368407:MEMAR RS06445
gene id: 368407:MEMAR_RS06445
uniprot id: A3CV44
names: Subcellular Location Annotation
messages: Membrane

368407:MEMAR RS01595
gene id: 368407:MEMAR_RS01595
uniprot id: A3CSB6
names: Similarity
messages: Belongs to the glutamate synthase family.

368407:MEMAR RS11060
gene id: 368407:MEMAR_RS11060
uniprot id: A3CXR3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EIF2G subfamily.
messages: Heterotrimer composed of an alpha, a beta and a gamma chain.
messages: eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA.

368407:MEMAR RS02295
gene id: 368407:MEMAR_RS02295
uniprot id: A3CSQ6
names: Function
names: Similarity
messages: Belongs to the TFIIB family.
messages: Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB).

368407:MEMAR RS10235
gene id: 368407:MEMAR_RS10235
uniprot id: A3CX98
names: Subcellular Location Annotation
messages: Membrane

368407:MEMAR RS05005
gene id: 368407:MEMAR_RS05005
uniprot id: A3CUA1
names: Similarity
messages: Belongs to the UPF0235 family.

368407:MEMAR RS00275
gene id: 368407:MEMAR_RS00275
uniprot id: A3CRJ1
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

368407:MEMAR RS09710
gene id: 368407:MEMAR_RS09710
uniprot id: A3CWZ4
names: Function
names: Similarity
messages: Belongs to the eIF-6 family.
messages: Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex.

368407:MEMAR RS01220
gene id: 368407:MEMAR_RS01220
uniprot id: A3CS45
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).

368407:MEMAR RS03130
gene id: 368407:MEMAR_RS03130
uniprot id: A3CT71
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AP endonuclease 2 family.
messages: Binds 3 Zn(2+) ions.
messages: Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.

368407:MEMAR RS12290
gene id: 368407:MEMAR_RS12290
uniprot id: A3CYG1
names: Similarity
messages: Belongs to the DtxR/MntR family.

368407:MEMAR RS00425
gene id: 368407:MEMAR_RS00425
uniprot id: A3CRM1
names: Subcellular Location Annotation
messages: Membrane

368407:MEMAR RS03530
gene id: 368407:MEMAR_RS03530
uniprot id: A3CTF6
names: Subcellular Location Annotation
messages: Membrane

368407:MEMAR RS07895
gene id: 368407:MEMAR_RS07895
uniprot id: A3CVZ2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThiI family.
messages: Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

368407:MEMAR RS01930
gene id: 368407:MEMAR_RS01930
uniprot id: A3CSI6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

368407:MEMAR RS04080
gene id: 368407:MEMAR_RS04080
uniprot id: A3CTR6
names: Similarity
messages: Belongs to the MtxX family.

368407:MEMAR RS06420
gene id: 368407:MEMAR_RS06420
uniprot id: A3CV39
names: Similarity
messages: Belongs to the UPF0107 family.

368407:MEMAR RS08165
gene id: 368407:MEMAR_RS08165
uniprot id: A3CW44
names: Cofactor
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

368407:MEMAR RS09190
gene id: 368407:MEMAR_RS09190
uniprot id: A3CWP1
names: Function
names: Similarity
messages: Belongs to the ATP-dependent DNA ligase family.
messages: DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair.

368407:MEMAR RS02695
gene id: 368407:MEMAR_RS02695
uniprot id: A3CSY4
names: Function
names: Similarity
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. Type 2 subfamily.
messages: Catalyzes the conversion of AMP and phosphate to adenine and ribose 1,5-bisphosphate (R15P). Exhibits phosphorylase activity toward CMP and UMP in addition to AMP. Functions in an archaeal AMP degradation pathway, together with R15P isomerase and RubisCO.

368407:MEMAR RS06500
gene id: 368407:MEMAR_RS06500
uniprot id: A3CV55
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Because the Archaea possessing a type III RuBisCO are all anaerobic, it is most likely that only the carboxylase activity of RuBisCO, and not the competitive oxygenase activity (by which RuBP reacts with O(2) to form one molecule of 3-phosphoglycerate and one molecule of 2-phosphoglycolate), is biologically relevant in these strains.
messages: Belongs to the RuBisCO large chain family. Type III subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the addition of molecular CO(2) and H(2)O to ribulose 1,5-bisphosphate (RuBP), generating two molecules of 3-phosphoglycerate (3-PGA). Functions in an archaeal AMP degradation pathway, together with AMP phosphorylase and R15P isomerase.
messages: Homodimer or homodecamer. In contrast to form I RuBisCO, the form III RuBisCO is composed solely of large subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

368407:MEMAR RS05360
gene id: 368407:MEMAR_RS05360
uniprot id: A3CUH2
names: Similarity
messages: Belongs to the NadC/ModD family.

368407:MEMAR RS09700
gene id: 368407:MEMAR_RS09700
uniprot id: A3CWZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the prefoldin alpha subunit family.
messages: Cytoplasm
messages: Heterohexamer of two alpha and four beta subunits.
messages: Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding.

368407:MEMAR RS08245
gene id: 368407:MEMAR_RS08245
uniprot id: A3CW60
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

368407:MEMAR RS03455
gene id: 368407:MEMAR_RS03455
uniprot id: A3CTE1
names: Subunit
messages: Heterotetramer of one alpha, one beta, one delta and one gamma chain.

368407:MEMAR RS02895
gene id: 368407:MEMAR_RS02895
uniprot id: A3CT25
names: Function
names: Similarity
messages: Belongs to the V-ATPase V0D/AC39 subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

368407:MEMAR RS09365
gene id: 368407:MEMAR_RS09365
uniprot id: A3CWS6
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Heterodimer composed of a glutamine amidotransferase subunit (A) and a GMP-binding subunit (B).

368407:MEMAR RS09380
gene id: 368407:MEMAR_RS09380
uniprot id: A3CWS9
names: Caution
names: Function
names: Similarity
messages: Belongs to the adenylate kinase family. AK6 subfamily.
messages: Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

368407:MEMAR RS08275
gene id: 368407:MEMAR_RS08275
uniprot id: A3CW66
names: Similarity
names: Subunit
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
messages: Heterooligomer of catalytic and regulatory chains.

368407:MEMAR RS10905
gene id: 368407:MEMAR_RS10905
uniprot id: A3CXN2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

368407:MEMAR RS01115
gene id: 368407:MEMAR_RS01115
uniprot id: A3CS23
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

368407:MEMAR RS00845
gene id: 368407:MEMAR_RS00845
uniprot id: A3CRV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STT3 family.
messages: Membrane

368407:MEMAR RS04085
gene id: 368407:MEMAR_RS04085
uniprot id: A3CTR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal histone HMF family.
messages: Chromosome
messages: Cytoplasm

368407:MEMAR RS11635
gene id: 368407:MEMAR_RS11635
uniprot id: A3CY31
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.

368407:MEMAR RS07555
gene id: 368407:MEMAR_RS07555
uniprot id: A3CVS2
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

368407:MEMAR RS09390
gene id: 368407:MEMAR_RS09390
uniprot id: A3CWT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TspO/BZRP family.
messages: Membrane

368407:MEMAR RS03170
gene id: 368407:MEMAR_RS03170
uniprot id: A3CT79
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Catalyzes the hydrolysis of S-inosyl-L-homocysteine (SIH) to L-homocysteine (Hcy) and inosine. Likely functions in a S-adenosyl-L-methionine (SAM) recycling pathway from S-adenosyl-L-homocysteine (SAH) produced from SAM-dependent methylation reactions. Can also catalyze the reverse reaction in vitro, i.e. the synthesis of SIH from Hcy and inosine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: SAH is a product of SAM methyltransferases and is known to be a feedback inhibitor of these enzymes. As a result of this inhibition, organisms have evolved efficient enzymes to metabolize SAH via different pathways. The pathway found in methanogens differs from the canonical pathway, it uses the deamination of S-adenosyl-L-homocysteine to form S-inosyl-L-homocysteine for the regeneration of SAM from S-adenosyl-L-homocysteine.

368407:MEMAR RS11455
gene id: 368407:MEMAR_RS11455
uniprot id: A3CXZ4
names: Subunit
messages: Heterotetramer of one alpha, one beta, one delta and one gamma chain.

368407:MEMAR RS09210
gene id: 368407:MEMAR_RS09210
uniprot id: A3CWP5
names: Similarity
messages: Belongs to the peptidase C56 family.

368407:MEMAR RS02440
gene id: 368407:MEMAR_RS02440
uniprot id: A3CST5
names: Similarity
messages: Belongs to the band 7/mec-2 family.

368407:MEMAR RS09625
gene id: 368407:MEMAR_RS09625
uniprot id: A3CWX6
names: Caution
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

368407:MEMAR RS05550
gene id: 368407:MEMAR_RS05550
uniprot id: A3CUL3
names: Similarity
messages: Belongs to the AHA1 family.

368407:MEMAR RS11505
gene id: 368407:MEMAR_RS11505
uniprot id: A3CY04
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

368407:MEMAR RS02520
gene id: 368407:MEMAR_RS02520
uniprot id: A3CSV1
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

368407:MEMAR RS10885
gene id: 368407:MEMAR_RS10885
uniprot id: A3CXM8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

368407:MEMAR RS10345
gene id: 368407:MEMAR_RS10345
uniprot id: A3CXC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

368407:MEMAR RS03500
gene id: 368407:MEMAR_RS03500
uniprot id: A3CTF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Membrane

368407:MEMAR RS04375
gene id: 368407:MEMAR_RS04375
uniprot id: A3CTX6
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.

368407:MEMAR RS01345
gene id: 368407:MEMAR_RS01345
uniprot id: A3CS68
names: Function
names: Similarity
messages: Belongs to the V-ATPase E subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

368407:MEMAR RS06700
gene id: 368407:MEMAR_RS06700
uniprot id: A3CV96
names: Similarity
messages: Belongs to the DeoC/FbaB aldolase family.

368407:MEMAR RS02435
gene id: 368407:MEMAR_RS02435
uniprot id: A3CST4
names: Subcellular Location Annotation
messages: Membrane

368407:MEMAR RS07745
gene id: 368407:MEMAR_RS07745
uniprot id: A3CVW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal NMN adenylyltransferase family.
messages: Cytoplasm

368407:MEMAR RS03780
gene id: 368407:MEMAR_RS03780
uniprot id: A3CTK6
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

368407:MEMAR RS03890
gene id: 368407:MEMAR_RS03890
uniprot id: A3CTM9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

368407:MEMAR RS08295
gene id: 368407:MEMAR_RS08295
uniprot id: A3CW70
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HdrA family.
messages: Cytoplasm
messages: Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B).
messages: The ferredoxin:CoB-CoM heterodisulfide reductase is composed of three subunits; HdrA, HdrB and HdrC.

368407:MEMAR RS09550
gene id: 368407:MEMAR_RS09550
uniprot id: A3CWW1
names: Subcellular Location Annotation
messages: Membrane

368407:MEMAR RS08740
gene id: 368407:MEMAR_RS08740
uniprot id: A3CWF7
names: Subcellular Location Annotation
messages: Membrane

368407:MEMAR RS12025
gene id: 368407:MEMAR_RS12025
uniprot id: A3CYA7
names: Subcellular Location Annotation
messages: Membrane

368407:MEMAR RS03595
gene id: 368407:MEMAR_RS03595
uniprot id: A3CTG9
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Heterodimer composed of a glutamine amidotransferase subunit (A) and a GMP-binding subunit (B).

368407:MEMAR RS03730
gene id: 368407:MEMAR_RS03730
uniprot id: A3CTJ6
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

368407:MEMAR RS03210
gene id: 368407:MEMAR_RS03210
uniprot id: A3CT87
names: Similarity
messages: Belongs to the radical SAM superfamily. NifB family.

368407:MEMAR RS03945
gene id: 368407:MEMAR_RS03945
uniprot id: A3CTP0
names: Cofactor
names: Function
names: Subunit
messages: Binds 2 [4Fe-4S] clusters. In this family the first cluster has a non-standard and varying [4Fe-4S] binding motif CX(2)CX(2)CX(4-5)CP.
messages: Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.
messages: Heterodimer of the IorA and IorB subunits.

368407:MEMAR RS10245
gene id: 368407:MEMAR_RS10245
uniprot id: A3CXA0
names: Subcellular Location Annotation
messages: Membrane

368407:MEMAR RS03220
gene id: 368407:MEMAR_RS03220
uniprot id: A3CT91
names: Subcellular Location Annotation
messages: Membrane

368407:MEMAR RS00480
gene id: 368407:MEMAR_RS00480
uniprot id: A3CRN2
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.
messages: Membrane

368407:MEMAR RS02925
gene id: 368407:MEMAR_RS02925
uniprot id: A3CT31
names: Subcellular Location Annotation
messages: Membrane

368407:MEMAR RS01070
gene id: 368407:MEMAR_RS01070
uniprot id: A3CS14
names: Similarity
messages: Belongs to the snRNP Sm proteins family.

368407:MEMAR RS11335
gene id: 368407:MEMAR_RS11335
uniprot id: A3CXW9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the archaeal FAD synthase family.
messages: Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme.
messages: Homodimer.

368407:MEMAR RS06365
gene id: 368407:MEMAR_RS06365
uniprot id: A3CV28
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Monomer.

368407:MEMAR RS04175
gene id: 368407:MEMAR_RS04175
uniprot id: A3CTT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

368407:MEMAR RS01200
gene id: 368407:MEMAR_RS01200
uniprot id: A3CS41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

368407:MEMAR RS04935
gene id: 368407:MEMAR_RS04935
uniprot id: A3CU87
names: Caution
names: Function
names: Similarity
messages: Belongs to the ornithine cyclodeaminase/mu-crystallin family. Archaeal alanine dehydrogenase subfamily.
messages: Catalyzes the NAD(+)-dependent oxidative deamination of L-alanine to pyruvate, and the reverse reaction, the reductive amination of pyruvate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

368407:MEMAR RS10125
gene id: 368407:MEMAR_RS10125
uniprot id: A3CX75
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL42 family.
messages: Binds 1 zinc ion per subunit.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

368407:MEMAR RS03050
gene id: 368407:MEMAR_RS03050
uniprot id: A3CT56
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HdrA family.
messages: Cytoplasm
messages: Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B).
messages: The ferredoxin:CoB-CoM heterodisulfide reductase is composed of three subunits; HdrA, HdrB and HdrC.

368407:MEMAR RS03750
gene id: 368407:MEMAR_RS03750
uniprot id: A3CTK0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate.
messages: Homotrimer.

368407:MEMAR RS01295
gene id: 368407:MEMAR_RS01295
uniprot id: A3CS58
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA 3'-terminal cyclase family. Type 1 subfamily.
messages: Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing.
messages: Cytoplasm

368407:MEMAR RS03625
gene id: 368407:MEMAR_RS03625
uniprot id: A3CTH5
names: Similarity
messages: Belongs to the P(II) protein family.

368407:MEMAR RS12070
gene id: 368407:MEMAR_RS12070
uniprot id: A3CYB6
names: Function
names: Similarity
messages: Belongs to the EF-1-beta/EF-1-delta family.
messages: Promotes the exchange of GDP for GTP in EF-1-alpha/GDP, thus allowing the regeneration of EF-1-alpha/GTP that could then be used to form the ternary complex EF-1-alpha/GTP/AAtRNA.

368407:MEMAR RS07790
gene id: 368407:MEMAR_RS07790
uniprot id: A3CVX0
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

368407:MEMAR RS07045
gene id: 368407:MEMAR_RS07045
uniprot id: A3CVG8
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

368407:MEMAR RS12770
gene id: 368407:MEMAR_RS12770
uniprot id: A3CW52
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal Rpo12/eukaryotic RPC10 RNA polymerase subunit family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

368407:MEMAR RS02500
gene id: 368407:MEMAR_RS02500
uniprot id: A3CSU7
names: Function
names: Similarity
messages: Belongs to the CbiD family.
messages: Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.

368407:MEMAR RS08840
gene id: 368407:MEMAR_RS08840
uniprot id: A3CWH6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

368407:MEMAR RS07100
gene id: 368407:MEMAR_RS07100
uniprot id: A3CVH8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

368407:MEMAR RS11075
gene id: 368407:MEMAR_RS11075
uniprot id: A3CXR6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the archaeal Spt4 family.
messages: Heterodimer composed of Spt4 and Spt5.
messages: Stimulates transcription elongation.

368407:MEMAR RS01050
gene id: 368407:MEMAR_RS01050
uniprot id: A3CS10
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

368407:MEMAR RS04845
gene id: 368407:MEMAR_RS04845
uniprot id: A3CU69
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.

368407:MEMAR RS01355
gene id: 368407:MEMAR_RS01355
uniprot id: A3CS70
names: Function
names: Similarity
messages: Belongs to the V-ATPase F subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

368407:MEMAR RS10090
gene id: 368407:MEMAR_RS10090
uniprot id: A3CX68
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.
messages: Cytoplasm
messages: Homodimer.

368407:MEMAR RS04795
gene id: 368407:MEMAR_RS04795
uniprot id: A3CU59
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

368407:MEMAR RS07860
gene id: 368407:MEMAR_RS07860
uniprot id: A3CVY5
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

368407:MEMAR RS06130
gene id: 368407:MEMAR_RS06130
uniprot id: A3CUX9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the activator 1 small subunits family. RfcS subfamily.
messages: Heteromultimer composed of small subunits (RfcS) and large subunits (RfcL).
messages: Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA.

368407:MEMAR RS05350
gene id: 368407:MEMAR_RS05350
uniprot id: A3CUH0
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of three SAM-derived enzymatic products, namely 5'-deoxyadenosine, S-adenosyl-L-homocysteine, and 5'-methylthioadenosine, to produce the inosine analogs. Can also deaminate adenosine. The preferred substrate for this enzyme is 5'-deoxyadenosine, but all these substrates are efficiently deaminated. Likely functions in a S-adenosyl-L-methionine (SAM) recycling pathway from S-adenosyl-L-homocysteine (SAH) produced from SAM-dependent methylation reactions. May also be involved in the recycling of 5'-deoxyadenosine, whereupon the 5'-deoxyribose moiety of 5'-deoxyinosine is further metabolized to deoxyhexoses used for the biosynthesis of aromatic amino acids in methanogens.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: SAH is a product of SAM methyltransferases and is known to be a feedback inhibitor of these enzymes. As a result of this inhibition, organisms have evolved efficient enzymes to metabolize SAH via different pathways. The pathway found in methanogens differs from the canonical pathway, it uses the deamination of S-adenosyl-L-homocysteine to form S-inosyl-L-homocysteine for the regeneration of SAM from S-adenosyl-L-homocysteine. 5'-deoxyadenosine is a radical SAM enzyme reaction product which strongly inhibits radical SAM enzymes. A pathway for removing this product must be present in methanogens where the MTA/SAH nucleosidase which normally metabolizes this compound is absent.

368407:MEMAR RS11085
gene id: 368407:MEMAR_RS11085
uniprot id: A3CXR8
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS24 family.

368407:MEMAR RS04740
gene id: 368407:MEMAR_RS04740
uniprot id: A3CU49
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eIF-5A family.
messages: Cytoplasm
messages: Functions by promoting the formation of the first peptide bond.

368407:MEMAR RS09505
gene id: 368407:MEMAR_RS09505
uniprot id: A3CWV2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the XPG/RAD2 endonuclease family. FEN1 subfamily.
messages: Binds 2 magnesium ions per subunit. They probably participate in the reaction catalyzed by the enzyme. May bind an additional third magnesium ion after substrate binding.
messages: Interacts with PCNA. PCNA stimulates the nuclease activity without altering cleavage specificity.
messages: Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. Acts as a genome stabilization factor that prevents flaps from equilibrating into structures that lead to duplications and deletions. Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA (By similarity).

368407:MEMAR RS11500
gene id: 368407:MEMAR_RS11500
uniprot id: A3CY03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

368407:MEMAR RS11055
gene id: 368407:MEMAR_RS11055
uniprot id: A3CXR2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the transcriptional regulatory CopG/NikR family.
messages: Binds 1 nickel ion per subunit.
messages: Transcriptional regulator.

368407:MEMAR RS06125
gene id: 368407:MEMAR_RS06125
uniprot id: A3CUX8
names: Similarity
messages: Belongs to the MCM family.

368407:MEMAR RS05320
gene id: 368407:MEMAR_RS05320
uniprot id: A3CUG5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the beta-RFA-P synthase family.
messages: Catalyzes the condensation of 4-aminobenzoate (pABA) with 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to produce beta-ribofuranosylaminobenzene 5'-phosphate (beta-RFA-P).
messages: Homodimer.

368407:MEMAR RS07620
gene id: 368407:MEMAR_RS07620
uniprot id: A3CVT5
names: Similarity
messages: Belongs to the UPF0200 family.

368407:MEMAR RS04970
gene id: 368407:MEMAR_RS04970
uniprot id: A3CU94
names: Similarity
messages: Belongs to the ParA family. MinD subfamily.

368407:MEMAR RS08195
gene id: 368407:MEMAR_RS08195
uniprot id: A3CW49
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the prefoldin subunit beta family.
messages: Cytoplasm
messages: Heterohexamer of two alpha and four beta subunits.
messages: Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding.

368407:MEMAR RS09375
gene id: 368407:MEMAR_RS09375
uniprot id: A3CWS8
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.

368407:MEMAR RS02460
gene id: 368407:MEMAR_RS02460
uniprot id: A3CST9
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the geranylgeranyl reductase family. DGGGPL reductase subfamily.
messages: Binds 1 FAD per subunit.
messages: Is involved in the reduction of 2,3-digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains.
messages: Reduction reaction proceeds via syn addition of hydrogen for double bonds.

368407:MEMAR RS01740
gene id: 368407:MEMAR_RS01740
uniprot id: A3CSE6
names: Subcellular Location Annotation
messages: Membrane

368407:MEMAR RS05825
gene id: 368407:MEMAR_RS05825
uniprot id: A3CUS0
names: Similarity
messages: Belongs to the FwdC/FmdC family.

368407:MEMAR RS02870
gene id: 368407:MEMAR_RS02870
uniprot id: A3CT20
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of alpha (SecY), beta (SecG) and gamma (SecE) subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. May interact with SecDF, and other proteins may be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

368407:MEMAR RS04335
gene id: 368407:MEMAR_RS04335
uniprot id: A3CTW8
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

368407:MEMAR RS08145
gene id: 368407:MEMAR_RS08145
uniprot id: A3CW40
names: Similarity
messages: Belongs to the UPF0215 family.

368407:MEMAR RS07405
gene id: 368407:MEMAR_RS07405
uniprot id: A3CVP2
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

368407:MEMAR RS04815
gene id: 368407:MEMAR_RS04815
uniprot id: A3CU63
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

368407:MEMAR RS07630
gene id: 368407:MEMAR_RS07630
uniprot id: A3CVT7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

368407:MEMAR RS11120
gene id: 368407:MEMAR_RS11120
uniprot id: A3CXS5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

368407:MEMAR RS09900
gene id: 368407:MEMAR_RS09900
uniprot id: A3CX32
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

368407:MEMAR RS04160
gene id: 368407:MEMAR_RS04160
uniprot id: A3CTT2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

368407:MEMAR RS04150
gene id: 368407:MEMAR_RS04150
uniprot id: A3CTT0
names: Similarity
messages: Belongs to the class-I fumarase family.

368407:MEMAR RS02560
gene id: 368407:MEMAR_RS02560
uniprot id: A3CSV9
names: Subcellular Location Annotation
messages: Membrane

368407:MEMAR RS02975
gene id: 368407:MEMAR_RS02975
uniprot id: A3CT41
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MtrA family.
messages: Binds 1 5-hydroxybenzimidazolylcobamide group.
messages: Cell membrane
messages: Part of a complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step.
messages: The complex is composed of 8 subunits; MtrA, MtrB, MtrC, MtrD, MtrE, MtrF, MtrG and MtrH.

368407:MEMAR RS02880
gene id: 368407:MEMAR_RS02880
uniprot id: A3CT22
names: Subcellular Location Annotation
messages: Membrane

368407:MEMAR RS12050
gene id: 368407:MEMAR_RS12050
uniprot id: A3CYB2
names: Subcellular Location Annotation
messages: Membrane

368407:MEMAR RS09095
gene id: 368407:MEMAR_RS09095
uniprot id: A3CWM3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. Archaeal HPRT subfamily.
messages: Catalyzes a salvage reaction resulting in the formation of IMP that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

368407:MEMAR RS06295
gene id: 368407:MEMAR_RS06295
uniprot id: A3CV15
names: Similarity
messages: Belongs to the UPF0145 family.

368407:MEMAR RS03535
gene id: 368407:MEMAR_RS03535
uniprot id: A3CTF7
names: Similarity
messages: Belongs to the glycosyltransferase 2 family.

368407:MEMAR RS06695
gene id: 368407:MEMAR_RS06695
uniprot id: A3CV95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

368407:MEMAR RS06355
gene id: 368407:MEMAR_RS06355
uniprot id: A3CV26
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reduced FMN (FMNH(2)).

368407:MEMAR RS09640
gene id: 368407:MEMAR_RS09640
uniprot id: A3CWY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S16 family.
messages: Membrane

368407:MEMAR RS10800
gene id: 368407:MEMAR_RS10800
uniprot id: A3CXL1
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

368407:MEMAR RS10585
gene id: 368407:MEMAR_RS10585
uniprot id: A3CXG7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CofD family.
messages: Catalyzes the transfer of the 2-phospholactate moiety from (2S)-lactyl-2-diphospho-5'-guanosine to 7,8-didemethyl-8-hydroxy-5-deazariboflavin (FO) with the formation of oxidized coenzyme F420-0 and GMP.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

368407:MEMAR RS04625
gene id: 368407:MEMAR_RS04625
uniprot id: A3CU24
names: Function
names: Similarity
messages: Belongs to the CheD family.
messages: Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.

368407:MEMAR RS09745
gene id: 368407:MEMAR_RS09745
uniprot id: A3CX01
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic/archaeal RNase P protein component 4 family.
messages: Binds 1 zinc ion per subunit.
messages: Consists of a catalytic RNA component and at least 4-5 protein subunits.
messages: Cytoplasm
messages: Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.

368407:MEMAR RS04820
gene id: 368407:MEMAR_RS04820
uniprot id: A3CU64
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

368407:MEMAR RS12205
gene id: 368407:MEMAR_RS12205
uniprot id: A3CYE4
names: Subcellular Location Annotation
messages: Membrane

368407:MEMAR RS05150
gene id: 368407:MEMAR_RS05150
uniprot id: A3CUD0
names: Similarity
messages: Belongs to the tRNA methyltransferase O family.

368407:MEMAR RS04095
gene id: 368407:MEMAR_RS04095
uniprot id: A3CTR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

368407:MEMAR RS02800
gene id: 368407:MEMAR_RS02800
uniprot id: A3CT06
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

368407:MEMAR RS10555
gene id: 368407:MEMAR_RS10555
uniprot id: A3CXG0
names: Similarity
messages: Belongs to the glutamate synthase family.

368407:MEMAR RS10935
gene id: 368407:MEMAR_RS10935
uniprot id: A3CXN8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. O-phosphoseryl-tRNA(Cys) synthetase subfamily.
messages: Catalyzes the attachment of O-phosphoserine (Sep) to tRNA(Cys).
messages: Homotetramer. Interacts with SepCysS.

368407:MEMAR RS11010
gene id: 368407:MEMAR_RS11010
uniprot id: A3CXQ3
names: Similarity
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.

368407:MEMAR RS09685
gene id: 368407:MEMAR_RS09685
uniprot id: A3CWY9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methyltransferase superfamily. TrmY family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically catalyzes the N1-methylation of pseudouridine at position 54 (Psi54) in tRNAs.

368407:MEMAR RS06060
gene id: 368407:MEMAR_RS06060
uniprot id: A3CUW5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the archaeal phosphopantothenate synthetase family.
messages: Catalyzes the condensation of (R)-4-phosphopantoate and beta-alanine to 4'-phosphopantothenate in the CoA biosynthesis pathway.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

368407:MEMAR RS08280
gene id: 368407:MEMAR_RS08280
uniprot id: A3CW67
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PyrI family.
messages: Binds 1 zinc ion per subunit.
messages: Contains catalytic and regulatory chains.
messages: Involved in allosteric regulation of aspartate carbamoyltransferase.

368407:MEMAR RS06350
gene id: 368407:MEMAR_RS06350
uniprot id: A3CV25
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-I 3-dehydroquinase family.
messages: Homodimer.
messages: Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate.

368407:MEMAR RS12600
gene id: 368407:MEMAR_RS12600
uniprot id: A3CS13
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL37 family.
messages: Binds 1 zinc ion per subunit.
messages: Binds to the 23S rRNA.

368407:MEMAR RS06955
gene id: 368407:MEMAR_RS06955
uniprot id: A3CVE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm

368407:MEMAR RS04865
gene id: 368407:MEMAR_RS04865
uniprot id: A3CU73
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

368407:MEMAR RS02395
gene id: 368407:MEMAR_RS02395
uniprot id: A3CSS6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

368407:MEMAR RS06305
gene id: 368407:MEMAR_RS06305
uniprot id: A3CV17
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the archaeosine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs.

368407:MEMAR RS06790
gene id: 368407:MEMAR_RS06790
uniprot id: A3CVB4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

368407:MEMAR RS09070
gene id: 368407:MEMAR_RS09070
uniprot id: A3CWL8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ferredoxin thioredoxin reductase beta subunit family.
messages: Catalytic subunit of the ferredoxin-thioredoxin reductase (FTR), which catalyzes the two-electron reduction of thioredoxins by the electrons provided by reduced ferredoxin.
messages: Heterodimer of subunit A (variable subunit) and subunit B (catalytic subunit). Heterodimeric FTR forms a complex with ferredoxin and thioredoxin.

368407:MEMAR RS10940
gene id: 368407:MEMAR_RS10940
uniprot id: A3CXN9
names: Similarity
messages: In the C-terminal section; belongs to the trehalose phosphatase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 20 family.

368407:MEMAR RS09735
gene id: 368407:MEMAR_RS09735
uniprot id: A3CWZ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS19 family.
messages: May be involved in maturation of the 30S ribosomal subunit.
messages: Part of the 30S ribosomal subunit.

368407:MEMAR RS03115
gene id: 368407:MEMAR_RS03115
uniprot id: A3CT68
names: Similarity
messages: Belongs to the LeuD family. LeuD type 2 subfamily.

368407:MEMAR RS02830
gene id: 368407:MEMAR_RS02830
uniprot id: A3CT12
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit.

368407:MEMAR RS06215
gene id: 368407:MEMAR_RS06215
uniprot id: A3CUZ4
names: Similarity
messages: Belongs to the glycosyl hydrolase 57 family.

368407:MEMAR RS02965
gene id: 368407:MEMAR_RS02965
uniprot id: A3CT39
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MtrA family.
messages: Belongs to the MtrG family.
messages: Binds 1 5-hydroxybenzimidazolylcobamide group.
messages: Cell membrane
messages: Part of a complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step.
messages: The complex is composed of 8 subunits; MtrA, MtrB, MtrC, MtrD, MtrE, MtrF, MtrG and MtrH.

368407:MEMAR RS00235
gene id: 368407:MEMAR_RS00235
uniprot id: A3CRI3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. CofH family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated synthesis of 5-amino-5-(4-hydroxybenzyl)-6-(D-ribitylimino)-5,6-dihydrouracil from 5-amino-6-(D-ribitylamino)uracil and L-tyrosine.
messages: Consists of two subunits, CofG and CofH.

368407:MEMAR RS04615
gene id: 368407:MEMAR_RS04615
uniprot id: A3CU22
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

368407:MEMAR RS02725
gene id: 368407:MEMAR_RS02725
uniprot id: A3CSY9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CetZ family.
messages: Cytoplasm
messages: Involved in cell shape control.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

368407:MEMAR RS06165
gene id: 368407:MEMAR_RS06165
uniprot id: A3CUY5
names: Similarity
messages: Belongs to the tRNA methyltransferase O family.

368407:MEMAR RS01130
gene id: 368407:MEMAR_RS01130
uniprot id: A3CS26
names: Subcellular Location Annotation
messages: Membrane

368407:MEMAR RS11115
gene id: 368407:MEMAR_RS11115
uniprot id: A3CXS4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the THI4 family.
messages: Homooctamer; tetramer of dimers.
messages: Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur.

368407:MEMAR RS07900
gene id: 368407:MEMAR_RS07900
uniprot id: A3CVZ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SepCysS family.
messages: Converts O-phospho-L-seryl-tRNA(Cys) (Sep-tRNA(Cys)) to L-cysteinyl-tRNA(Cys) (Cys-tRNA(Cys)).
messages: Homodimer. Interacts with SepRS.

368407:MEMAR RS11670
gene id: 368407:MEMAR_RS11670
uniprot id: A3CY38
names: Similarity
messages: Belongs to the HMG-CoA reductase family.

368407:MEMAR RS10240
gene id: 368407:MEMAR_RS10240
uniprot id: A3CX99
names: Subcellular Location Annotation
messages: Membrane

368407:MEMAR RS01905
gene id: 368407:MEMAR_RS01905
uniprot id: A3CSI1
names: Function
names: Similarity
messages: Belongs to the archaeal 6-HMPDK family.
messages: Catalyzes the transfer of diphosphate from ATP to 6-hydroxymethyl-7,8-dihydropterin (6-HMD), leading to 6-hydroxymethyl-7,8-dihydropterin diphosphate (6-HMDP).

368407:MEMAR RS04720
gene id: 368407:MEMAR_RS04720
uniprot id: A3CU45
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Archaeal flagellum
messages: Belongs to the archaeal flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of archaeal flagella.

368407:MEMAR RS04920
gene id: 368407:MEMAR_RS04920
uniprot id: A3CU84
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.

368407:MEMAR RS02885
gene id: 368407:MEMAR_RS02885
uniprot id: A3CT23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 2 subfamily.
messages: Cytoplasm

368407:MEMAR RS00285
gene id: 368407:MEMAR_RS00285
uniprot id: A3CRJ3
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

368407:MEMAR RS03990
gene id: 368407:MEMAR_RS03990
uniprot id: A3CTP8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

368407:MEMAR RS09970
gene id: 368407:MEMAR_RS09970
uniprot id: A3CX43
names: Similarity
messages: Belongs to the TrpF family.

368407:MEMAR RS09435
gene id: 368407:MEMAR_RS09435
uniprot id: A3CWT8
names: Similarity
messages: Belongs to the CutA family.

368407:MEMAR RS01360
gene id: 368407:MEMAR_RS01360
uniprot id: A3CS71
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit.

368407:MEMAR RS08910
gene id: 368407:MEMAR_RS08910
uniprot id: A3CWJ1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease activity. May be involved in RNA degradation.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Archaeal RNase J subfamily.
messages: Binds 2 Zn(2+) ions per subunit. It is not clear if Zn(2+) or Mg(2+) is physiologically important.
messages: Cytoplasm
messages: Homodimer.

368407:MEMAR RS08420
gene id: 368407:MEMAR_RS08420
uniprot id: A3CW92
names: Subcellular Location Annotation
messages: Cell membrane

368407:MEMAR RS11630
gene id: 368407:MEMAR_RS11630
uniprot id: A3CY30
names: Similarity
messages: Belongs to the site-specific recombinase resolvase family.

368407:MEMAR RS05540
gene id: 368407:MEMAR_RS05540
uniprot id: A3CUL1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

368407:MEMAR RS01980
gene id: 368407:MEMAR_RS01980
uniprot id: A3CSJ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. Probably involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of its operon by binding to its mRNA.

368407:MEMAR RS07350
gene id: 368407:MEMAR_RS07350
uniprot id: A3CVN1
names: Subcellular Location Annotation
messages: Membrane

368407:MEMAR RS02875
gene id: 368407:MEMAR_RS02875
uniprot id: A3CT21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal adenylate kinase family.
messages: Cytoplasm

368407:MEMAR RS03865
gene id: 368407:MEMAR_RS03865
uniprot id: A3CTM3
names: Function
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.

368407:MEMAR RS05220
gene id: 368407:MEMAR_RS05220
uniprot id: A3CUE4
names: Function
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.

368407:MEMAR RS10340
gene id: 368407:MEMAR_RS10340
uniprot id: A3CXB9
names: Similarity
messages: Belongs to the peptidase S13 family.

368407:MEMAR RS11090
gene id: 368407:MEMAR_RS11090
uniprot id: A3CXR9
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS31 family.
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the 30S ribosomal subunit.

368407:MEMAR RS01925
gene id: 368407:MEMAR_RS01925
uniprot id: A3CSI5
names: Similarity
messages: Belongs to the tRNA(His) guanylyltransferase family.

368407:MEMAR RS09355
gene id: 368407:MEMAR_RS09355
uniprot id: A3CWS4
names: Similarity
messages: Belongs to the thioesterase PaaI family.

368407:MEMAR RS04100
gene id: 368407:MEMAR_RS04100
uniprot id: A3CTS0
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Feedback inhibited by histidine.

368407:MEMAR RS12030
gene id: 368407:MEMAR_RS12030
uniprot id: A3CYA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

368407:MEMAR RS11940
gene id: 368407:MEMAR_RS11940
uniprot id: A3CY90
names: Subcellular Location Annotation
messages: Cell membrane

368407:MEMAR RS02890
gene id: 368407:MEMAR_RS02890
uniprot id: A3CT24
names: Function
names: Similarity
messages: Belongs to the V-ATPase D subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

368407:MEMAR RS01955
gene id: 368407:MEMAR_RS01955
uniprot id: A3CSJ1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DtdA deacylase family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: D-aminoacyl-tRNA deacylase with broad substrate specificity. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo.
messages: Monomer.