365046:RTA RS16200
gene id: 365046:RTA_RS16200
uniprot id: F5XXE5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

365046:RTA RS01680
gene id: 365046:RTA_RS01680
uniprot id: F5Y596
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family. Prx5 subfamily.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

365046:RTA RS02345
gene id: 365046:RTA_RS02345
uniprot id: F5Y631
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

365046:RTA RS19545
gene id: 365046:RTA_RS19545
uniprot id: F5Y358
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell inner membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

365046:RTA RS00765
gene id: 365046:RTA_RS00765
uniprot id: F5Y3D5
names: Similarity
messages: Belongs to the glutathione peroxidase family.

365046:RTA RS08915
gene id: 365046:RTA_RS08915
uniprot id: F5XVR5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

365046:RTA RS17115
gene id: 365046:RTA_RS17115
uniprot id: F5XYU3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

365046:RTA RS08575
gene id: 365046:RTA_RS08575
uniprot id: F5Y676
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

365046:RTA RS19010
gene id: 365046:RTA_RS19010
uniprot id: F5Y263
names: Similarity
messages: Belongs to the glutathione peroxidase family.

365046:RTA RS03655
gene id: 365046:RTA_RS03655
uniprot id: F5XXJ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

365046:RTA RS13460
gene id: 365046:RTA_RS13460
uniprot id: F5Y3S5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

365046:RTA RS03675
gene id: 365046:RTA_RS03675
uniprot id: F5XXJ5
names: Similarity
messages: Belongs to the DSD1 family.

365046:RTA RS21280
gene id: 365046:RTA_RS21280
uniprot id: F5Y6G7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

365046:RTA RS15925
gene id: 365046:RTA_RS15925
uniprot id: F5XWT0
names: Similarity
messages: Belongs to the CcdB toxin family.

365046:RTA RS00740
gene id: 365046:RTA_RS00740
uniprot id: F5Y3D0
names: Cofactor
names: Function
messages: Binds 2 [4Fe-4S] clusters.
messages: Component of a complex that catalyzes the oxidation of glycolate to glyoxylate.

365046:RTA RS19380
gene id: 365046:RTA_RS19380
uniprot id: F5Y324
names: Domain
names: Function
names: Subcellular Location Annotation
messages: Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation.
messages: Periplasm
messages: The PPIase activity resides only in the second parvulin domain. The N-terminal region and the C-terminal tail are necessary and sufficient for the chaperone activity of SurA. The PPIase activity is dispensable for SurA to function as a chaperone. The N-terminal region and the C-terminal tail are also required for porin recognition.

365046:RTA RS19225
gene id: 365046:RTA_RS19225
uniprot id: F5Y2Z4
names: Similarity
messages: Belongs to the glutamine synthetase family.

365046:RTA RS12895
gene id: 365046:RTA_RS12895
uniprot id: F5Y2S2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

365046:RTA RS18250
gene id: 365046:RTA_RS18250
uniprot id: F5Y0T9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

365046:RTA RS04100
gene id: 365046:RTA_RS04100
uniprot id: F5XY88
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial secretin family. PilQ subfamily.
messages: Cell outer membrane
messages: Homododecamer. Tetramer of trimer.
messages: Required for type IV pilus biogenesis and competence. Could function as a pore for exit of the pilus but also as a channel for entry of heme and antimicrobial agents and uptake of transforming DNA.

365046:RTA RS09230
gene id: 365046:RTA_RS09230
uniprot id: F5XWD5
names: Similarity
messages: Belongs to the glutamine synthetase family.

365046:RTA RS01645
gene id: 365046:RTA_RS01645
uniprot id: F5Y589
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

365046:RTA RS07240
gene id: 365046:RTA_RS07240
uniprot id: F5Y436
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

365046:RTA RS17500
gene id: 365046:RTA_RS17500
uniprot id: F5XZH7
names: Similarity
messages: Belongs to the peptidase M42 family.

365046:RTA RS09030
gene id: 365046:RTA_RS09030
uniprot id: F5XVT8
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

365046:RTA RS02740
gene id: 365046:RTA_RS02740
uniprot id: F5XVP2
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

365046:RTA RS18845
gene id: 365046:RTA_RS18845
uniprot id: F5Y230
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.
messages: One is catalytic and the other provides a structural contribution.

365046:RTA RS18545
gene id: 365046:RTA_RS18545
uniprot id: F5Y1F3
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

365046:RTA RS14930
gene id: 365046:RTA_RS14930
uniprot id: F5Y6E5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Plays an essential role in type IV pili and type II pseudopili formation by proteolytically removing the leader sequence from substrate proteins and subsequently monomethylating the alpha-amino group of the newly exposed N-terminal phenylalanine.

365046:RTA RS13975
gene id: 365046:RTA_RS13975
uniprot id: F5Y4I8
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.

365046:RTA RS16695
gene id: 365046:RTA_RS16695
uniprot id: F5XY55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

365046:RTA RS10855
gene id: 365046:RTA_RS10855
uniprot id: F5XZ45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

365046:RTA RS09280
gene id: 365046:RTA_RS09280
uniprot id: F5XWE6
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

365046:RTA RS18520
gene id: 365046:RTA_RS18520
uniprot id: F5Y1E8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

365046:RTA RS14120
gene id: 365046:RTA_RS14120
uniprot id: F5Y522
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

365046:RTA RS17285
gene id: 365046:RTA_RS17285
uniprot id: F5XZD6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.

365046:RTA RS05480
gene id: 365046:RTA_RS05480
uniprot id: F5Y0D3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the trans-sulfuration enzymes family. MetZ subfamily.
messages: Catalyzes the formation of L-homocysteine from O-succinyl-L-homoserine (OSHS) and hydrogen sulfide.
messages: Homotetramer.

365046:RTA RS04760
gene id: 365046:RTA_RS04760
uniprot id: F5XZ26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

365046:RTA RS09575
gene id: 365046:RTA_RS09575
uniprot id: F5XWK4
names: Function
names: Subunit
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
messages: Homodimer. Part of the PDH complex, consisting of multiple copies of pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

365046:RTA RS09720
gene id: 365046:RTA_RS09720
uniprot id: F5XX42
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

365046:RTA RS14425
gene id: 365046:RTA_RS14425
uniprot id: F5Y5N6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

365046:RTA RS07330
gene id: 365046:RTA_RS07330
uniprot id: F5Y458
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

365046:RTA RS17765
gene id: 365046:RTA_RS17765
uniprot id: F5Y037
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated exonuclease Cas4 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).
messages: Mg(2+) or Mn(2+) required for ssDNA cleavage activity.

365046:RTA RS01620
gene id: 365046:RTA_RS01620
uniprot id: F5Y584
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

365046:RTA RS06970
gene id: 365046:RTA_RS06970
uniprot id: F5Y3H3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LapB family.
messages: Cell inner membrane
messages: Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane.

365046:RTA RS06720
gene id: 365046:RTA_RS06720
uniprot id: F5Y2N6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial solute-binding protein 7 family.
messages: Homodimer.
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: Periplasm

365046:RTA RS04280
gene id: 365046:RTA_RS04280
uniprot id: F5XYC4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

365046:RTA RS13545
gene id: 365046:RTA_RS13545
uniprot id: F5Y3U1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

365046:RTA RS19440
gene id: 365046:RTA_RS19440
uniprot id: F5Y337
names: Similarity
messages: Belongs to the four-carbon acid sugar kinase family.

365046:RTA RS03720
gene id: 365046:RTA_RS03720
uniprot id: F5XXK4
names: Subcellular Location Annotation
messages: Mitochondrion

365046:RTA RS17715
gene id: 365046:RTA_RS17715
uniprot id: F5Y027
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The autoendoproteolytic cleavage occurs by a canonical serine protease mechanism, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. During this reaction, the Ser that is part of the protease active site of the proenzyme becomes the pyruvoyl prosthetic group, which constitutes an essential element of the active site of the mature decarboxylase.

365046:RTA RS15280
gene id: 365046:RTA_RS15280
uniprot id: F5XVY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YscJ lipoprotein family.
messages: Cell outer membrane
messages: Membrane

365046:RTA RS09130
gene id: 365046:RTA_RS09130
uniprot id: F5XVV7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

365046:RTA RS14395
gene id: 365046:RTA_RS14395
uniprot id: F5Y574
names: Cofactor
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.

365046:RTA RS06935
gene id: 365046:RTA_RS06935
uniprot id: F5Y3G6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

365046:RTA RS07635
gene id: 365046:RTA_RS07635
uniprot id: F5Y4S6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. DnaE2 subfamily.
messages: Cytoplasm
messages: DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase.

365046:RTA RS02880
gene id: 365046:RTA_RS02880
uniprot id: F5XW71
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

365046:RTA RS13310
gene id: 365046:RTA_RS13310
uniprot id: F5Y3P5
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

365046:RTA RS05300
gene id: 365046:RTA_RS05300
uniprot id: F5Y099
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

365046:RTA RS11225
gene id: 365046:RTA_RS11225
uniprot id: F5XZS8
names: Similarity
messages: Belongs to the UPF0434 family.

365046:RTA RS15010
gene id: 365046:RTA_RS15010
uniprot id: F5Y6G2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

365046:RTA RS18050
gene id: 365046:RTA_RS18050
uniprot id: F5Y0P9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
messages: Homotetramer.

365046:RTA RS01955
gene id: 365046:RTA_RS01955
uniprot id: F5Y5E9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.

365046:RTA RS01005
gene id: 365046:RTA_RS01005
uniprot id: F5Y3Z1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

365046:RTA RS01800
gene id: 365046:RTA_RS01800
uniprot id: F5Y5C0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a(1), b(1), b'(1) and c(9-12).
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

365046:RTA RS01920
gene id: 365046:RTA_RS01920
uniprot id: F5Y5E3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Membrane

365046:RTA RS10025
gene id: 365046:RTA_RS10025
uniprot id: F5XXR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

365046:RTA RS01730
gene id: 365046:RTA_RS01730
uniprot id: F5Y5A6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

365046:RTA RS08890
gene id: 365046:RTA_RS08890
uniprot id: F5XVR2
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

365046:RTA RS11885
gene id: 365046:RTA_RS11885
uniprot id: F5Y0L3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

365046:RTA RS06265
gene id: 365046:RTA_RS06265
uniprot id: F5Y1Q9
names: Subcellular Location Annotation
messages: Membrane

365046:RTA RS07205
gene id: 365046:RTA_RS07205
uniprot id: F5Y3M0
names: Similarity
messages: Belongs to the YciI family.

365046:RTA RS16965
gene id: 365046:RTA_RS16965
uniprot id: F5XYR4
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

365046:RTA RS16915
gene id: 365046:RTA_RS16915
uniprot id: F5XYQ5
names: Similarity
messages: Belongs to the glycosyl hydrolase 24 family.

365046:RTA RS04805
gene id: 365046:RTA_RS04805
uniprot id: F5XZJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

365046:RTA RS13575
gene id: 365046:RTA_RS13575
uniprot id: F5Y3U7
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

365046:RTA RS10740
gene id: 365046:RTA_RS10740
uniprot id: F5XYL7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family.
messages: Cytoplasm
messages: Homotrimer.

365046:RTA RS05250
gene id: 365046:RTA_RS05250
uniprot id: F5Y090
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

365046:RTA RS05525
gene id: 365046:RTA_RS05525
uniprot id: F5Y0E0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

365046:RTA RS09400
gene id: 365046:RTA_RS09400
uniprot id: F5XWH0
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

365046:RTA RS14875
gene id: 365046:RTA_RS14875
uniprot id: F5Y6D5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

365046:RTA RS07610
gene id: 365046:RTA_RS07610
uniprot id: F5Y4S1
names: Similarity
messages: Belongs to the DNA glycosylase MPG family.

365046:RTA RS01940
gene id: 365046:RTA_RS01940
uniprot id: F5Y5E7
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

365046:RTA RS09715
gene id: 365046:RTA_RS09715
uniprot id: F5XX41
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

365046:RTA RS14845
gene id: 365046:RTA_RS14845
uniprot id: F5Y6C9
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

365046:RTA RS19140
gene id: 365046:RTA_RS19140
uniprot id: F5Y289
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

365046:RTA RS01205
gene id: 365046:RTA_RS01205
uniprot id: F5Y4J1
names: Similarity
messages: Belongs to the prokaryotic GSH synthase family.

365046:RTA RS03430
gene id: 365046:RTA_RS03430
uniprot id: F5XWY6
names: Similarity
messages: Belongs to the GST superfamily. NadH family.

365046:RTA RS09840
gene id: 365046:RTA_RS09840
uniprot id: F5XX66
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 2 residues (Tyr-69 and Arg-72) present in a large hydrophobic pocket are probably involved in substrate specificity. They are important for desuccinylation activity, but dispensable for deacetylation activity.
messages: Belongs to the sirtuin family. Class III subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form.

365046:RTA RS04995
gene id: 365046:RTA_RS04995
uniprot id: F5XZN3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

365046:RTA RS04715
gene id: 365046:RTA_RS04715
uniprot id: F5XZ17
names: Similarity
messages: Belongs to the YciI family.

365046:RTA RS12030
gene id: 365046:RTA_RS12030
uniprot id: F5Y147
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

365046:RTA RS06510
gene id: 365046:RTA_RS06510
uniprot id: F5Y2J7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

365046:RTA RS13970
gene id: 365046:RTA_RS13970
uniprot id: F5Y4I7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Membrane

365046:RTA RS07930
gene id: 365046:RTA_RS07930
uniprot id: F5Y4Y3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

365046:RTA RS03855
gene id: 365046:RTA_RS03855
uniprot id: F5XXN1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

365046:RTA RS16210
gene id: 365046:RTA_RS16210
uniprot id: F5XXE7
names: Subcellular Location Annotation
messages: Membrane

365046:RTA RS04205
gene id: 365046:RTA_RS04205
uniprot id: F5XYA9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

365046:RTA RS16175
gene id: 365046:RTA_RS16175
uniprot id: F5XXE0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LolA family.
messages: Monomer.
messages: Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).
messages: Periplasm

365046:RTA RS03970
gene id: 365046:RTA_RS03970
uniprot id: F5XXQ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Homotetramer.

365046:RTA RS09555
gene id: 365046:RTA_RS09555
uniprot id: F5XWK0
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

365046:RTA RS01790
gene id: 365046:RTA_RS01790
uniprot id: F5Y5B8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell inner membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

365046:RTA RS04790
gene id: 365046:RTA_RS04790
uniprot id: F5XZ32
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

365046:RTA RS18065
gene id: 365046:RTA_RS18065
uniprot id: F5Y0Q2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP G family.
messages: Cell inner membrane
messages: Membrane

365046:RTA RS14300
gene id: 365046:RTA_RS14300
uniprot id: F5Y555
names: Function
names: Similarity
names: Subunit
messages: Belongs to the kynureninase family.
messages: Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
messages: Homodimer.

365046:RTA RS03455
gene id: 365046:RTA_RS03455
uniprot id: F5XWZ2
names: Subcellular Location Annotation
messages: Membrane

365046:RTA RS09500
gene id: 365046:RTA_RS09500
uniprot id: F5XWJ0
names: Similarity
messages: Belongs to the leucine-binding protein family.

365046:RTA RS11200
gene id: 365046:RTA_RS11200
uniprot id: F5XZS3
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

365046:RTA RS02805
gene id: 365046:RTA_RS02805
uniprot id: F5XW56
names: Similarity
messages: Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.

365046:RTA RS00395
gene id: 365046:RTA_RS00395
uniprot id: F5Y2G8
names: Similarity
messages: Belongs to the PrpD family.

365046:RTA RS14090
gene id: 365046:RTA_RS14090
uniprot id: F5Y516
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TspO/BZRP family.
messages: Membrane

365046:RTA RS09245
gene id: 365046:RTA_RS09245
uniprot id: F5XWD8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

365046:RTA RS08985
gene id: 365046:RTA_RS08985
uniprot id: F5XVS9
names: Similarity
messages: Belongs to the skp family.

365046:RTA RS10405
gene id: 365046:RTA_RS10405
uniprot id: F5XXY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

365046:RTA RS18465
gene id: 365046:RTA_RS18465
uniprot id: F5Y1D7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

365046:RTA RS19170
gene id: 365046:RTA_RS19170
uniprot id: F5Y2Y3
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

365046:RTA RS00010
gene id: 365046:RTA_RS00010
uniprot id: F5Y1J9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

365046:RTA RS12775
gene id: 365046:RTA_RS12775
uniprot id: F5Y210
names: Similarity
messages: Belongs to the UPF0229 family.

365046:RTA RS04450
gene id: 365046:RTA_RS04450
uniprot id: F5XYW2
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

365046:RTA RS13700
gene id: 365046:RTA_RS13700
uniprot id: F5Y4D2
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

365046:RTA RS17905
gene id: 365046:RTA_RS17905
uniprot id: F5Y065
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

365046:RTA RS02390
gene id: 365046:RTA_RS02390
uniprot id: F5XVH2
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

365046:RTA RS05010
gene id: 365046:RTA_RS05010
uniprot id: F5XZN6
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

365046:RTA RS12590
gene id: 365046:RTA_RS12590
uniprot id: F5Y1X3
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

365046:RTA RS06560
gene id: 365046:RTA_RS06560
uniprot id: F5Y2K7
names: Similarity
messages: Belongs to the pseudomonas-type ThrB family.

365046:RTA RS10165
gene id: 365046:RTA_RS10165
uniprot id: F5XXT8
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.

365046:RTA RS08955
gene id: 365046:RTA_RS08955
uniprot id: F5XVS3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

365046:RTA RS13295
gene id: 365046:RTA_RS13295
uniprot id: F5Y3P2
names: Similarity
messages: Belongs to the bacterial ring-hydroxylating dioxygenase beta subunit family.

365046:RTA RS17595
gene id: 365046:RTA_RS17595
uniprot id: F5Y003
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

365046:RTA RS06945
gene id: 365046:RTA_RS06945
uniprot id: F5Y3G8
names: Similarity
messages: Belongs to the oxoprolinase family.

365046:RTA RS05175
gene id: 365046:RTA_RS05175
uniprot id: F5XZR8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

365046:RTA RS05110
gene id: 365046:RTA_RS05110
uniprot id: F5XZQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

365046:RTA RS04165
gene id: 365046:RTA_RS04165
uniprot id: F5XYA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MlaE permease family.
messages: Cell inner membrane
messages: Membrane

365046:RTA RS00610
gene id: 365046:RTA_RS00610
uniprot id: F5Y3A3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.
messages: Cytoplasm
messages: Monomer.

365046:RTA RS15215
gene id: 365046:RTA_RS15215
uniprot id: F5XVX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type III secretion exporter family.
messages: Cell membrane
messages: Membrane

365046:RTA RS13915
gene id: 365046:RTA_RS13915
uniprot id: F5Y4H6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

365046:RTA RS02100
gene id: 365046:RTA_RS02100
uniprot id: F5Y5Y2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

365046:RTA RS19885
gene id: 365046:RTA_RS19885
uniprot id: F5XVX9
names: Similarity
messages: Belongs to the transglycosylase Slt family.

365046:RTA RS17265
gene id: 365046:RTA_RS17265
uniprot id: F5XZD2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Binds a copper A center.
messages: Cell membrane
messages: Membrane
messages: Periplasm
messages: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).

365046:RTA RS12385
gene id: 365046:RTA_RS12385
uniprot id: F5Y1B7
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

365046:RTA RS04985
gene id: 365046:RTA_RS04985
uniprot id: F5XZN0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

365046:RTA RS02090
gene id: 365046:RTA_RS02090
uniprot id: F5Y5Y0
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the peroxidase family. Peroxidase/catalase subfamily.
messages: Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.
messages: Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

365046:RTA RS14990
gene id: 365046:RTA_RS14990
uniprot id: F5Y6F8
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

365046:RTA RS08550
gene id: 365046:RTA_RS08550
uniprot id: F5Y671
names: Similarity
messages: Belongs to the PrpD family.

365046:RTA RS11340
gene id: 365046:RTA_RS11340
uniprot id: F5XZV1
names: Subcellular Location Annotation
messages: Periplasm

365046:RTA RS00350
gene id: 365046:RTA_RS00350
uniprot id: F5Y2F9
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

365046:RTA RS07720
gene id: 365046:RTA_RS07720
uniprot id: F5Y4U2
names: Similarity
messages: Belongs to the pirin family.

365046:RTA RS07215
gene id: 365046:RTA_RS07215
uniprot id: F5Y431
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

365046:RTA RS08975
gene id: 365046:RTA_RS08975
uniprot id: F5XVS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

365046:RTA RS16180
gene id: 365046:RTA_RS16180
uniprot id: F5XXE1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Essential cell division protein that coordinates cell division and chromosome segregation. The N-terminus is involved in assembly of the cell-division machinery. The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region. Translocation stops specifically at Xer-dif sites, where FtsK interacts with the Xer recombinase, allowing activation of chromosome unlinking by recombination. FtsK orienting polar sequences (KOPS) guide the direction of DNA translocation. FtsK can remove proteins from DNA as it translocates, but translocation stops specifically at XerCD-dif site, thereby preventing removal of XerC and XerD from dif.
messages: Membrane

365046:RTA RS02515
gene id: 365046:RTA_RS02515
uniprot id: F5XVJ7
names: Similarity
messages: Belongs to the UPF0102 family.

365046:RTA RS12550
gene id: 365046:RTA_RS12550
uniprot id: F5Y1W4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

365046:RTA RS09140
gene id: 365046:RTA_RS09140
uniprot id: F5XVV9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

365046:RTA RS03515
gene id: 365046:RTA_RS03515
uniprot id: F5XX05
names: Similarity
messages: Belongs to the phosphohexose mutase family.

365046:RTA RS16365
gene id: 365046:RTA_RS16365
uniprot id: F5XXH8
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

365046:RTA RS17150
gene id: 365046:RTA_RS17150
uniprot id: F5XYU9
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

365046:RTA RS04690
gene id: 365046:RTA_RS04690
uniprot id: F5XZ12
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

365046:RTA RS17955
gene id: 365046:RTA_RS17955
uniprot id: F5Y075
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

365046:RTA RS19035
gene id: 365046:RTA_RS19035
uniprot id: F5Y268
names: Similarity
messages: Belongs to the sodium:galactoside symporter (TC 2.A.2) family.

365046:RTA RS11215
gene id: 365046:RTA_RS11215
uniprot id: F5XZS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

365046:RTA RS12020
gene id: 365046:RTA_RS12020
uniprot id: F5Y145
names: Function
messages: Member of the two-component regulatory system PhoR/PhoB involved in the phosphate regulon genes expression. PhoR may function as a membrane-associated protein kinase that phosphorylates PhoB in response to environmental signals.

365046:RTA RS14420
gene id: 365046:RTA_RS14420
uniprot id: F5Y5N5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

365046:RTA RS12025
gene id: 365046:RTA_RS12025
uniprot id: F5Y146
names: Function
messages: This protein is a positive regulator for the phosphate regulon. Transcription of this operon is positively regulated by PhoB and PhoR when phosphate is limited.

365046:RTA RS05365
gene id: 365046:RTA_RS05365
uniprot id: F5Y0B1
names: Function
names: Similarity
messages: Belongs to the BCKDHA family.
messages: The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).

365046:RTA RS05280
gene id: 365046:RTA_RS05280
uniprot id: F5Y096
names: Subcellular Location Annotation
messages: Membrane

365046:RTA RS04270
gene id: 365046:RTA_RS04270
uniprot id: F5XYC2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell inner membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

365046:RTA RS13530
gene id: 365046:RTA_RS13530
uniprot id: F5Y3T8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

365046:RTA RS09560
gene id: 365046:RTA_RS09560
uniprot id: F5XWK1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

365046:RTA RS03735
gene id: 365046:RTA_RS03735
uniprot id: F5XXK7
names: Subcellular Location Annotation
messages: Membrane

365046:RTA RS03035
gene id: 365046:RTA_RS03035
uniprot id: F5XWA2
names: Subcellular Location Annotation
messages: Membrane

365046:RTA RS02620
gene id: 365046:RTA_RS02620
uniprot id: F5XVL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

365046:RTA RS12475
gene id: 365046:RTA_RS12475
uniprot id: F5Y1V1
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily.
messages: Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA.

365046:RTA RS19365
gene id: 365046:RTA_RS19365
uniprot id: F5Y321
names: Similarity
messages: Belongs to the ribonuclease N1/T1 family.

365046:RTA RS10150
gene id: 365046:RTA_RS10150
uniprot id: F5XXT5
names: Similarity
messages: Belongs to the peptidase S66 family.

365046:RTA RS09375
gene id: 365046:RTA_RS09375
uniprot id: F5XWG5
names: Similarity
messages: Belongs to the ACC deaminase/D-cysteine desulfhydrase family.

365046:RTA RS10070
gene id: 365046:RTA_RS10070
uniprot id: F5XXR9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

365046:RTA RS01615
gene id: 365046:RTA_RS01615
uniprot id: F5Y583
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

365046:RTA RS11645
gene id: 365046:RTA_RS11645
uniprot id: F5Y0G5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

365046:RTA RS05645
gene id: 365046:RTA_RS05645
uniprot id: F5Y0W8
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

365046:RTA RS07430
gene id: 365046:RTA_RS07430
uniprot id: F5Y478
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0761 family.
messages: Cell inner membrane
messages: Membrane

365046:RTA RS04045
gene id: 365046:RTA_RS04045
uniprot id: F5XY78
names: Subcellular Location Annotation
messages: Membrane

365046:RTA RS04420
gene id: 365046:RTA_RS04420
uniprot id: F5XYV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

365046:RTA RS03695
gene id: 365046:RTA_RS03695
uniprot id: F5XXJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

365046:RTA RS18685
gene id: 365046:RTA_RS18685
uniprot id: F5Y1I1
names: Subcellular Location Annotation
messages: Membrane

365046:RTA RS18815
gene id: 365046:RTA_RS18815
uniprot id: F5Y224
names: Similarity
messages: Belongs to the thioredoxin family.

365046:RTA RS12595
gene id: 365046:RTA_RS12595
uniprot id: F5Y1X4
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

365046:RTA RS11990
gene id: 365046:RTA_RS11990
uniprot id: F5Y139
names: Similarity
messages: Belongs to the thioredoxin family.

365046:RTA RS11605
gene id: 365046:RTA_RS11605
uniprot id: F5Y0F7
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

365046:RTA RS01640
gene id: 365046:RTA_RS01640
uniprot id: F5Y588
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

365046:RTA RS11230
gene id: 365046:RTA_RS11230
uniprot id: F5XZS9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

365046:RTA RS16460
gene id: 365046:RTA_RS16460
uniprot id: F5XY07
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia.

365046:RTA RS12745
gene id: 365046:RTA_RS12745
uniprot id: F5Y204
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

365046:RTA RS13890
gene id: 365046:RTA_RS13890
uniprot id: F5Y4H1
names: Similarity
messages: Belongs to the DEAD box helicase family.

365046:RTA RS04930
gene id: 365046:RTA_RS04930
uniprot id: F5XZL9
names: Function
names: Similarity
messages: Belongs to the transpeptidase family. FtsI subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall at the division septum.

365046:RTA RS14555
gene id: 365046:RTA_RS14555
uniprot id: F5Y5R2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

365046:RTA RS14750
gene id: 365046:RTA_RS14750
uniprot id: F5Y5V0
names: Function
names: Similarity
messages: Belongs to the RlpA family.
messages: Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.

365046:RTA RS08085
gene id: 365046:RTA_RS08085
uniprot id: F5Y5H2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

365046:RTA RS08525
gene id: 365046:RTA_RS08525
uniprot id: F5Y666
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

365046:RTA RS08965
gene id: 365046:RTA_RS08965
uniprot id: F5XVS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

365046:RTA RS11720
gene id: 365046:RTA_RS11720
uniprot id: F5Y0I0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the R-transferase family. Bpt subfamily.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate.

365046:RTA RS18265
gene id: 365046:RTA_RS18265
uniprot id: F5Y0U2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

365046:RTA RS14515
gene id: 365046:RTA_RS14515
uniprot id: F5Y5Q4
names: Similarity
messages: Belongs to the heat shock protein 70 family.

365046:RTA RS09955
gene id: 365046:RTA_RS09955
uniprot id: F5XX88
names: Subcellular Location Annotation
messages: Membrane

365046:RTA RS14780
gene id: 365046:RTA_RS14780
uniprot id: F5Y5V6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

365046:RTA RS05005
gene id: 365046:RTA_RS05005
uniprot id: F5XZN5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RuvC family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.

365046:RTA RS14560
gene id: 365046:RTA_RS14560
uniprot id: F5Y5R3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell inner membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

365046:RTA RS15025
gene id: 365046:RTA_RS15025
uniprot id: F5Y6G5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

365046:RTA RS09805
gene id: 365046:RTA_RS09805
uniprot id: F5XX59
names: Similarity
messages: Belongs to the UxaA family.

365046:RTA RS14355
gene id: 365046:RTA_RS14355
uniprot id: F5Y566
names: Cofactor
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.

365046:RTA RS07960
gene id: 365046:RTA_RS07960
uniprot id: F5Y4Y9
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

365046:RTA RS08030
gene id: 365046:RTA_RS08030
uniprot id: F5Y5G2
names: Subcellular Location Annotation
messages: Membrane

365046:RTA RS17445
gene id: 365046:RTA_RS17445
uniprot id: F5XZG6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

365046:RTA RS18505
gene id: 365046:RTA_RS18505
uniprot id: F5Y1E5
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

365046:RTA RS14185
gene id: 365046:RTA_RS14185
uniprot id: F5Y534
names: Cofactor
messages: Binds 3 heme c groups covalently per subunit.

365046:RTA RS05275
gene id: 365046:RTA_RS05275
uniprot id: F5Y095
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase C15 family.
messages: Cytoplasm
messages: Homotetramer.
messages: Removes 5-oxoproline from various penultimate amino acid residues except L-proline.

365046:RTA RS01115
gene id: 365046:RTA_RS01115
uniprot id: F5Y413
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamE family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

365046:RTA RS06730
gene id: 365046:RTA_RS06730
uniprot id: F5Y2N8
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell inner membrane
messages: Membrane

365046:RTA RS13515
gene id: 365046:RTA_RS13515
uniprot id: F5Y3T6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

365046:RTA RS18455
gene id: 365046:RTA_RS18455
uniprot id: F5Y1D5
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

365046:RTA RS18805
gene id: 365046:RTA_RS18805
uniprot id: F5Y222
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.

365046:RTA RS15555
gene id: 365046:RTA_RS15555
uniprot id: F5XW47
names: Subcellular Location Annotation
messages: Membrane

365046:RTA RS03630
gene id: 365046:RTA_RS03630
uniprot id: F5XXI6
names: Subcellular Location Annotation
messages: Membrane

365046:RTA RS13370
gene id: 365046:RTA_RS13370
uniprot id: F5Y3Q7
names: Similarity
messages: Belongs to the HipA Ser/Thr kinase family.

365046:RTA RS06985
gene id: 365046:RTA_RS06985
uniprot id: F5Y3H6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS1 family.

365046:RTA RS08615
gene id: 365046:RTA_RS08615
uniprot id: F5Y684
names: Subcellular Location Annotation
messages: Membrane

365046:RTA RS16785
gene id: 365046:RTA_RS16785
uniprot id: F5XYN0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease beta subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

365046:RTA RS19430
gene id: 365046:RTA_RS19430
uniprot id: F5Y335
names: Similarity
messages: Belongs to the hyi family.

365046:RTA RS06195
gene id: 365046:RTA_RS06195
uniprot id: F5Y1P5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

365046:RTA RS16535
gene id: 365046:RTA_RS16535
uniprot id: F5XY23
names: Subcellular Location Annotation
messages: Membrane

365046:RTA RS17340
gene id: 365046:RTA_RS17340
uniprot id: F5XZE6
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit A family.

365046:RTA RS06025
gene id: 365046:RTA_RS06025
uniprot id: F5Y1L2
names: Subcellular Location Annotation
messages: Membrane

365046:RTA RS01050
gene id: 365046:RTA_RS01050
uniprot id: F5Y400
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

365046:RTA RS13780
gene id: 365046:RTA_RS13780
uniprot id: F5Y4E8
names: Similarity
messages: Belongs to the TPP enzyme family.

365046:RTA RS00570
gene id: 365046:RTA_RS00570
uniprot id: F5Y394
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

365046:RTA RS05360
gene id: 365046:RTA_RS05360
uniprot id: F5Y0B0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell inner membrane
messages: Probably interacts with PlsX.

365046:RTA RS00015
gene id: 365046:RTA_RS00015
uniprot id: F5Y1K0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

365046:RTA RS17735
gene id: 365046:RTA_RS17735
uniprot id: F5Y031
names: Similarity
messages: Belongs to the OsmC/Ohr family.

365046:RTA RS02275
gene id: 365046:RTA_RS02275
uniprot id: F5Y617
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

365046:RTA RS18680
gene id: 365046:RTA_RS18680
uniprot id: F5Y1I0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyltransferase 20 family.
messages: Homotetramer.
messages: Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-alpha-D-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor.

365046:RTA RS06250
gene id: 365046:RTA_RS06250
uniprot id: F5Y1Q6
names: Similarity
messages: Belongs to the leucine-binding protein family.

365046:RTA RS02810
gene id: 365046:RTA_RS02810
uniprot id: F5XW57
names: Cofactor
names: Similarity
messages: Belongs to the 4HPPD family.
messages: Binds 1 Fe cation per subunit.

365046:RTA RS06205
gene id: 365046:RTA_RS06205
uniprot id: F5Y1P7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

365046:RTA RS07405
gene id: 365046:RTA_RS07405
uniprot id: F5Y473
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

365046:RTA RS01865
gene id: 365046:RTA_RS01865
uniprot id: F5Y5D3
names: Subcellular Location Annotation
messages: Membrane

365046:RTA RS18325
gene id: 365046:RTA_RS18325
uniprot id: F5Y0V0
names: Similarity
messages: Belongs to the TrpC family.

365046:RTA RS16815
gene id: 365046:RTA_RS16815
uniprot id: F5XYN5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

365046:RTA RS13205
gene id: 365046:RTA_RS13205
uniprot id: F5Y3M4
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

365046:RTA RS09800
gene id: 365046:RTA_RS09800
uniprot id: F5XX58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

365046:RTA RS04060
gene id: 365046:RTA_RS04060
uniprot id: F5XY81
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

365046:RTA RS01565
gene id: 365046:RTA_RS01565
uniprot id: F5Y4R5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

365046:RTA RS07970
gene id: 365046:RTA_RS07970
uniprot id: F5Y4Z1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

365046:RTA RS12080
gene id: 365046:RTA_RS12080
uniprot id: F5Y157
names: Subcellular Location Annotation
messages: Membrane

365046:RTA RS07455
gene id: 365046:RTA_RS07455
uniprot id: F5Y482
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

365046:RTA RS01815
gene id: 365046:RTA_RS01815
uniprot id: F5Y5C3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

365046:RTA RS09105
gene id: 365046:RTA_RS09105
uniprot id: F5XVV2
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

365046:RTA RS06950
gene id: 365046:RTA_RS06950
uniprot id: F5Y3G9
names: Similarity
messages: Belongs to the DinB family.

365046:RTA RS16225
gene id: 365046:RTA_RS16225
uniprot id: F5XXF0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

365046:RTA RS08100
gene id: 365046:RTA_RS08100
uniprot id: F5Y5H5
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

365046:RTA RS03595
gene id: 365046:RTA_RS03595
uniprot id: F5XXH9
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

365046:RTA RS09050
gene id: 365046:RTA_RS09050
uniprot id: F5XVU1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

365046:RTA RS06170
gene id: 365046:RTA_RS06170
uniprot id: F5Y1P0
names: Subcellular Location Annotation
messages: Membrane

365046:RTA RS17705
gene id: 365046:RTA_RS17705
uniprot id: F5Y025
names: Function
names: Similarity
messages: Belongs to the AMP nucleosidase family.
messages: Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations.

365046:RTA RS12280
gene id: 365046:RTA_RS12280
uniprot id: F5Y196
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

365046:RTA RS05430
gene id: 365046:RTA_RS05430
uniprot id: F5Y0C3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 2 subfamily.
messages: Cytoplasm
messages: Homotetramer.

365046:RTA RS14205
gene id: 365046:RTA_RS14205
uniprot id: F5Y536
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
messages: Cell inner membrane

365046:RTA RS07535
gene id: 365046:RTA_RS07535
uniprot id: F5Y498
names: Cofactor
names: Function
messages: Accepts electrons from ETF and reduces ubiquinone.
messages: Binds 1 [4Fe-4S] cluster.

365046:RTA RS09540
gene id: 365046:RTA_RS09540
uniprot id: F5XWJ7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

365046:RTA RS12635
gene id: 365046:RTA_RS12635
uniprot id: F5Y1Y2
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaved by autocatalysis into a large and a small subunit.
messages: This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide.

365046:RTA RS13385
gene id: 365046:RTA_RS13385
uniprot id: F5Y3R0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

365046:RTA RS16230
gene id: 365046:RTA_RS16230
uniprot id: F5XXF1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

365046:RTA RS03010
gene id: 365046:RTA_RS03010
uniprot id: F5XW97
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

365046:RTA RS01040
gene id: 365046:RTA_RS01040
uniprot id: F5Y3Z8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PNT beta subunit family.
messages: Cell inner membrane
messages: Membrane
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

365046:RTA RS12235
gene id: 365046:RTA_RS12235
uniprot id: F5Y187
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK.

365046:RTA RS02430
gene id: 365046:RTA_RS02430
uniprot id: F5XVI0
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIS family. GmhA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
messages: Cytoplasm
messages: Homotetramer.
messages: The reaction produces a racemic mixture of D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate.

365046:RTA RS16045
gene id: 365046:RTA_RS16045
uniprot id: F5XXB3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

365046:RTA RS11590
gene id: 365046:RTA_RS11590
uniprot id: F5XZZ9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
messages: Cytoplasm

365046:RTA RS12450
gene id: 365046:RTA_RS12450
uniprot id: F5Y1U6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

365046:RTA RS15910
gene id: 365046:RTA_RS15910
uniprot id: F5XWS7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase D family. Cardiolipin synthase subfamily. ClsB sub-subfamily.
messages: Catalyzes the phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
messages: Cell membrane

365046:RTA RS04865
gene id: 365046:RTA_RS04865
uniprot id: F5XZK6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.

365046:RTA RS03820
gene id: 365046:RTA_RS03820
uniprot id: F5XXM4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

365046:RTA RS03000
gene id: 365046:RTA_RS03000
uniprot id: F5XW95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

365046:RTA RS19135
gene id: 365046:RTA_RS19135
uniprot id: F5Y288
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

365046:RTA RS16255
gene id: 365046:RTA_RS16255
uniprot id: F5XXF6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

365046:RTA RS07845
gene id: 365046:RTA_RS07845
uniprot id: F5Y4W7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

365046:RTA RS11255
gene id: 365046:RTA_RS11255
uniprot id: F5XZT4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

365046:RTA RS04200
gene id: 365046:RTA_RS04200
uniprot id: F5XYA8
names: Similarity
messages: Belongs to the BolA/IbaG family.

365046:RTA RS04725
gene id: 365046:RTA_RS04725
uniprot id: F5XZ19
names: Similarity
messages: Belongs to the YciI family.

365046:RTA RS03835
gene id: 365046:RTA_RS03835
uniprot id: F5XXM7
names: Similarity
messages: Belongs to the gluconokinase GntK/GntV family.

365046:RTA RS01390
gene id: 365046:RTA_RS01390
uniprot id: F5Y4M8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptA family.
messages: Component of the lipopolysaccharide transport and assembly complex.
messages: Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane.
messages: Periplasm

365046:RTA RS11170
gene id: 365046:RTA_RS11170
uniprot id: F5XZA8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK.

365046:RTA RS12065
gene id: 365046:RTA_RS12065
uniprot id: F5Y154
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

365046:RTA RS04210
gene id: 365046:RTA_RS04210
uniprot id: F5XYB0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Lacks the C-terminal regulatory region which is replaced by HisZ.

365046:RTA RS03020
gene id: 365046:RTA_RS03020
uniprot id: F5XW99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

365046:RTA RS03335
gene id: 365046:RTA_RS03335
uniprot id: F5XWW8
names: Subcellular Location Annotation
messages: Membrane

365046:RTA RS03135
gene id: 365046:RTA_RS03135
uniprot id: F5XWC2
names: Subcellular Location Annotation
messages: Membrane

365046:RTA RS17215
gene id: 365046:RTA_RS17215
uniprot id: F5XZC1
names: Similarity
messages: Belongs to the SCO1/2 family.

365046:RTA RS11210
gene id: 365046:RTA_RS11210
uniprot id: F5XZS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

365046:RTA RS12335
gene id: 365046:RTA_RS12335
uniprot id: F5Y1A7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

365046:RTA RS12290
gene id: 365046:RTA_RS12290
uniprot id: F5Y198
names: Similarity
messages: Belongs to the threonine synthase family.

365046:RTA RS12325
gene id: 365046:RTA_RS12325
uniprot id: F5Y1A5
names: Similarity
messages: Belongs to the PhoH family.

365046:RTA RS14630
gene id: 365046:RTA_RS14630
uniprot id: F5Y5S7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YceF subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes 7-methyl-GTP (m(7)GTP). May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

365046:RTA RS05135
gene id: 365046:RTA_RS05135
uniprot id: F5XZR0
names: Subcellular Location Annotation
messages: Membrane

365046:RTA RS11900
gene id: 365046:RTA_RS11900
uniprot id: F5Y0L6
names: Similarity
messages: Belongs to the transglycosylase Slt family.

365046:RTA RS13455
gene id: 365046:RTA_RS13455
uniprot id: F5Y3S4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell inner membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

365046:RTA RS10030
gene id: 365046:RTA_RS10030
uniprot id: F5XXR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

365046:RTA RS11735
gene id: 365046:RTA_RS11735
uniprot id: F5Y0I3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homotetramer.

365046:RTA RS05610
gene id: 365046:RTA_RS05610
uniprot id: F5Y0W1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

365046:RTA RS15505
gene id: 365046:RTA_RS15505
uniprot id: F5XW37
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

365046:RTA RS11740
gene id: 365046:RTA_RS11740
uniprot id: F5Y0I4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homotetramer.

365046:RTA RS12735
gene id: 365046:RTA_RS12735
uniprot id: F5Y202
names: Subcellular Location Annotation
messages: Membrane

365046:RTA RS09635
gene id: 365046:RTA_RS09635
uniprot id: F5XX26
names: Function
names: Similarity
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.
messages: E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

365046:RTA RS13135
gene id: 365046:RTA_RS13135
uniprot id: F5Y2X0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

365046:RTA RS17105
gene id: 365046:RTA_RS17105
uniprot id: F5XYU1
names: Similarity
messages: Belongs to the IlvD/Edd family.

365046:RTA RS01335
gene id: 365046:RTA_RS01335
uniprot id: F5Y4L7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the malate synthase family. GlcB subfamily.
messages: Cytoplasm
messages: Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

365046:RTA RS16410
gene id: 365046:RTA_RS16410
uniprot id: F5XXZ7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Catalyzes the deamination of dCTP to dUTP.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

365046:RTA RS01000
gene id: 365046:RTA_RS01000
uniprot id: F5Y3Z0
names: Subcellular Location Annotation
messages: Membrane

365046:RTA RS13475
gene id: 365046:RTA_RS13475
uniprot id: F5Y3S8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

365046:RTA RS07840
gene id: 365046:RTA_RS07840
uniprot id: F5Y4W6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

365046:RTA RS08460
gene id: 365046:RTA_RS08460
uniprot id: F5Y653
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell inner membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

365046:RTA RS07350
gene id: 365046:RTA_RS07350
uniprot id: F5Y462
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

365046:RTA RS04055
gene id: 365046:RTA_RS04055
uniprot id: F5XY80
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MsrQ family.
messages: Binds 1 FMN per subunit.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Cell inner membrane
messages: Heterodimer of a catalytic subunit (MsrP) and a heme-binding subunit (MsrQ).
messages: Membrane
messages: Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain.

365046:RTA RS09765
gene id: 365046:RTA_RS09765
uniprot id: F5XX51
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
messages: This function is generally fulfilled by the C-terminal part of HisG, which is missing in some bacteria such as this one.

365046:RTA RS05475
gene id: 365046:RTA_RS05475
uniprot id: F5Y0D2
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

365046:RTA RS13430
gene id: 365046:RTA_RS13430
uniprot id: F5Y3R9
names: Subcellular Location Annotation
messages: Periplasm

365046:RTA RS12390
gene id: 365046:RTA_RS12390
uniprot id: F5Y1B8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterioferritin family.
messages: Iron-storage protein.
messages: Oligomer of 24 subunits, arranged as 12 dimers, that are packed together to form an approximately spherical molecule with a central cavity, in which large amounts of iron can be deposited.

365046:RTA RS00500
gene id: 365046:RTA_RS00500
uniprot id: F5Y377
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.

365046:RTA RS10600
gene id: 365046:RTA_RS10600
uniprot id: F5XYI8
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

365046:RTA RS00995
gene id: 365046:RTA_RS00995
uniprot id: F5Y3Y9
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

365046:RTA RS17310
gene id: 365046:RTA_RS17310
uniprot id: F5XZE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

365046:RTA RS12375
gene id: 365046:RTA_RS12375
uniprot id: F5Y1B5
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PSRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.

365046:RTA RS10110
gene id: 365046:RTA_RS10110
uniprot id: F5XXS7
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

365046:RTA RS19555
gene id: 365046:RTA_RS19555
uniprot id: F5Y360
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

365046:RTA RS17045
gene id: 365046:RTA_RS17045
uniprot id: F5XYS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

365046:RTA RS00360
gene id: 365046:RTA_RS00360
uniprot id: F5Y2G1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.

365046:RTA RS13875
gene id: 365046:RTA_RS13875
uniprot id: F5Y4G8
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

365046:RTA RS08675
gene id: 365046:RTA_RS08675
uniprot id: F5Y696
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

365046:RTA RS18745
gene id: 365046:RTA_RS18745
uniprot id: F5Y1J3
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

365046:RTA RS17065
gene id: 365046:RTA_RS17065
uniprot id: F5XYT3
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

365046:RTA RS01195
gene id: 365046:RTA_RS01195
uniprot id: F5Y429
names: Similarity
messages: Belongs to the GST superfamily.

365046:RTA RS12555
gene id: 365046:RTA_RS12555
uniprot id: F5Y1W5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

365046:RTA RS03650
gene id: 365046:RTA_RS03650
uniprot id: F5XXJ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

365046:RTA RS18430
gene id: 365046:RTA_RS18430
uniprot id: F5Y1D1
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG).

365046:RTA RS05100
gene id: 365046:RTA_RS05100
uniprot id: F5XZQ3
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

365046:RTA RS11500
gene id: 365046:RTA_RS11500
uniprot id: F5XZY1
names: Function
names: Similarity
messages: Belongs to the PhnJ family.
messages: Catalyzes the breakage of the C-P bond in alpha-D-ribose 1-methylphosphonate 5-phosphate (PRPn) forming alpha-D-ribose.

365046:RTA RS12300
gene id: 365046:RTA_RS12300
uniprot id: F5Y1A0
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

365046:RTA RS04600
gene id: 365046:RTA_RS04600
uniprot id: F5XYZ5
names: Similarity
messages: Belongs to the UxaA family.

365046:RTA RS02150
gene id: 365046:RTA_RS02150
uniprot id: F5Y5Z2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

365046:RTA RS14880
gene id: 365046:RTA_RS14880
uniprot id: F5Y6D6
names: Function
names: Similarity
messages: Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
messages: Belongs to the Nudix hydrolase family. RppH subfamily.

365046:RTA RS12005
gene id: 365046:RTA_RS12005
uniprot id: F5Y142
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family.
messages: Part of the 50S ribosomal subunit.

365046:RTA RS14790
gene id: 365046:RTA_RS14790
uniprot id: F5Y5V8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

365046:RTA RS08415
gene id: 365046:RTA_RS08415
uniprot id: F5Y644
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.

365046:RTA RS17745
gene id: 365046:RTA_RS17745
uniprot id: F5Y033
names: Similarity
messages: In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.
messages: In the central section; belongs to the CRISPR-associated helicase Cas3 family.

365046:RTA RS18110
gene id: 365046:RTA_RS18110
uniprot id: F5Y0R1
names: Similarity
messages: Belongs to the GSP E family.

365046:RTA RS17635
gene id: 365046:RTA_RS17635
uniprot id: F5Y011
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

365046:RTA RS11565
gene id: 365046:RTA_RS11565
uniprot id: F5XZZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic sulfate-binding protein family.
messages: Periplasm

365046:RTA RS14665
gene id: 365046:RTA_RS14665
uniprot id: F5Y5T4
names: Subcellular Location Annotation
messages: Membrane

365046:RTA RS02245
gene id: 365046:RTA_RS02245
uniprot id: F5Y611
names: Function
names: Similarity
messages: In the C-terminal section; belongs to the aldehyde dehydrogenase family.
messages: In the N-terminal section; belongs to the proline dehydrogenase family.
messages: Oxidizes proline to glutamate for use as a carbon and nitrogen source.

365046:RTA RS13625
gene id: 365046:RTA_RS13625
uniprot id: F5Y4B7
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.

365046:RTA RS06235
gene id: 365046:RTA_RS06235
uniprot id: F5Y1Q3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-to-5' exoribonuclease specific for small oligoribonucleotides.
messages: Belongs to the oligoribonuclease family.
messages: Cytoplasm

365046:RTA RS09000
gene id: 365046:RTA_RS09000
uniprot id: F5XVT2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
messages: Cytoplasm
messages: Homotrimer.
messages: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

365046:RTA RS06420
gene id: 365046:RTA_RS06420
uniprot id: F5Y2H8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial secretin family.
messages: Cell outer membrane

365046:RTA RS14455
gene id: 365046:RTA_RS14455
uniprot id: F5Y5P2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

365046:RTA RS09125
gene id: 365046:RTA_RS09125
uniprot id: F5XVV6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

365046:RTA RS17575
gene id: 365046:RTA_RS17575
uniprot id: F5Y000
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

365046:RTA RS10275
gene id: 365046:RTA_RS10275
uniprot id: F5XXW0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

365046:RTA RS16615
gene id: 365046:RTA_RS16615
uniprot id: F5XY39
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

365046:RTA RS09700
gene id: 365046:RTA_RS09700
uniprot id: F5XX38
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.

365046:RTA RS15690
gene id: 365046:RTA_RS15690
uniprot id: F5XWN3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate.
messages: Cytoplasm

365046:RTA RS09525
gene id: 365046:RTA_RS09525
uniprot id: F5XWJ4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

365046:RTA RS12580
gene id: 365046:RTA_RS12580
uniprot id: F5Y1X0
names: Similarity
messages: Belongs to the LOG family.

365046:RTA RS02325
gene id: 365046:RTA_RS02325
uniprot id: F5Y627
names: Similarity
messages: Belongs to the peptidase C40 family.

365046:RTA RS02180
gene id: 365046:RTA_RS02180
uniprot id: F5Y5Z8
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

365046:RTA RS12630
gene id: 365046:RTA_RS12630
uniprot id: F5Y1Y1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

365046:RTA RS04580
gene id: 365046:RTA_RS04580
uniprot id: F5XYY8
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

365046:RTA RS07300
gene id: 365046:RTA_RS07300
uniprot id: F5Y448
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

365046:RTA RS05315
gene id: 365046:RTA_RS05315
uniprot id: F5Y0A1
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

365046:RTA RS16080
gene id: 365046:RTA_RS16080
uniprot id: F5XXC1
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

365046:RTA RS18830
gene id: 365046:RTA_RS18830
uniprot id: F5Y227
names: Similarity
messages: Belongs to the SAICAR synthetase family.

365046:RTA RS05035
gene id: 365046:RTA_RS05035
uniprot id: F5XZP1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 51 family.
messages: Cell inner membrane
messages: Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors.

365046:RTA RS15085
gene id: 365046:RTA_RS15085
uniprot id: F5Y6H8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

365046:RTA RS14460
gene id: 365046:RTA_RS14460
uniprot id: F5Y5P3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

365046:RTA RS13520
gene id: 365046:RTA_RS13520
uniprot id: F5Y3T7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell inner membrane
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

365046:RTA RS16855
gene id: 365046:RTA_RS16855
uniprot id: F5XYP3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

365046:RTA RS15955
gene id: 365046:RTA_RS15955
uniprot id: F5XWT6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC1 family. UbiB subfamily.
messages: Cell inner membrane
messages: Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

365046:RTA RS03585
gene id: 365046:RTA_RS03585
uniprot id: F5XX19
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RlmJ family.
messages: Monomer.
messages: Specifically methylates the adenine in position 2030 of 23S rRNA.

365046:RTA RS03115
gene id: 365046:RTA_RS03115
uniprot id: F5XWB8
names: Subunit
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

365046:RTA RS18275
gene id: 365046:RTA_RS18275
uniprot id: F5Y0U4
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

365046:RTA RS10485
gene id: 365046:RTA_RS10485
uniprot id: F5XYG4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsbB family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein.

365046:RTA RS14285
gene id: 365046:RTA_RS14285
uniprot id: F5Y552
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

365046:RTA RS02445
gene id: 365046:RTA_RS02445
uniprot id: F5XVI3
names: Similarity
messages: Belongs to the CFA/CMAS family.

365046:RTA RS01765
gene id: 365046:RTA_RS01765
uniprot id: F5Y5B3
names: Similarity
messages: Belongs to the UPF0250 family.

365046:RTA RS11015
gene id: 365046:RTA_RS11015
uniprot id: F5XZ77
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

365046:RTA RS17880
gene id: 365046:RTA_RS17880
uniprot id: F5Y060
names: Subcellular Location Annotation
messages: Membrane

365046:RTA RS17155
gene id: 365046:RTA_RS17155
uniprot id: F5XYV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

365046:RTA RS10940
gene id: 365046:RTA_RS10940
uniprot id: F5XZ62
names: Similarity
messages: Belongs to the HsdR family.

365046:RTA RS05130
gene id: 365046:RTA_RS05130
uniprot id: F5XZQ9
names: Subcellular Location Annotation
messages: Membrane

365046:RTA RS16195
gene id: 365046:RTA_RS16195
uniprot id: F5XXE4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

365046:RTA RS10000
gene id: 365046:RTA_RS10000
uniprot id: F5XX96
names: Similarity
messages: Belongs to the band 7/mec-2 family.

365046:RTA RS18525
gene id: 365046:RTA_RS18525
uniprot id: F5Y1E9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

365046:RTA RS15190
gene id: 365046:RTA_RS15190
uniprot id: F5Y6J7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Membrane

365046:RTA RS06365
gene id: 365046:RTA_RS06365
uniprot id: F5Y1S9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

365046:RTA RS01810
gene id: 365046:RTA_RS01810
uniprot id: F5Y5C2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

365046:RTA RS08095
gene id: 365046:RTA_RS08095
uniprot id: F5Y5H4
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

365046:RTA RS05080
gene id: 365046:RTA_RS05080
uniprot id: F5XZQ0
names: Function
names: Similarity
messages: Belongs to the MurCDEF family. Mpl subfamily.
messages: Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl-meso-diaminopimelate by linking it to UDP-N-acetylmuramate.

365046:RTA RS19400
gene id: 365046:RTA_RS19400
uniprot id: F5Y328
names: Subcellular Location Annotation
messages: Membrane

365046:RTA RS01365
gene id: 365046:RTA_RS01365
uniprot id: F5Y4M3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

365046:RTA RS18855
gene id: 365046:RTA_RS18855
uniprot id: F5Y232
names: Similarity
messages: Belongs to the pyruvate kinase family.

365046:RTA RS17960
gene id: 365046:RTA_RS17960
uniprot id: F5Y076
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

365046:RTA RS04350
gene id: 365046:RTA_RS04350
uniprot id: F5XYD7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell inner membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

365046:RTA RS02715
gene id: 365046:RTA_RS02715
uniprot id: F5XVN7
names: Similarity
messages: Belongs to the PhzF family.

365046:RTA RS06350
gene id: 365046:RTA_RS06350
uniprot id: F5Y1S6
names: Similarity
messages: Belongs to the DSD1 family.

365046:RTA RS02450
gene id: 365046:RTA_RS02450
uniprot id: F5XVI4
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

365046:RTA RS18295
gene id: 365046:RTA_RS18295
uniprot id: F5Y584
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

365046:RTA RS05060
gene id: 365046:RTA_RS05060
uniprot id: F5XZP6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. MrdB/RodA subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell wall elongation.

365046:RTA RS17435
gene id: 365046:RTA_RS17435
uniprot id: F5XZG4
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.

365046:RTA RS14740
gene id: 365046:RTA_RS14740
uniprot id: F5Y5U8
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

365046:RTA RS01630
gene id: 365046:RTA_RS01630
uniprot id: F5Y586
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: Methylated by PrmB.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

365046:RTA RS17565
gene id: 365046:RTA_RS17565
uniprot id: F5XZJ0
names: Function
names: Similarity
messages: Belongs to the phenylacetyl-CoA ligase family.
messages: Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).

365046:RTA RS03700
gene id: 365046:RTA_RS03700
uniprot id: F5XXK0
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

365046:RTA RS09695
gene id: 365046:RTA_RS09695
uniprot id: F5XX37
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

365046:RTA RS14925
gene id: 365046:RTA_RS14925
uniprot id: F5Y6E4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

365046:RTA RS18420
gene id: 365046:RTA_RS18420
uniprot id: F5Y1C9
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

365046:RTA RS13865
gene id: 365046:RTA_RS13865
uniprot id: F5Y4G6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

365046:RTA RS04665
gene id: 365046:RTA_RS04665
uniprot id: F5XZ08
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

365046:RTA RS18970
gene id: 365046:RTA_RS18970
uniprot id: F5Y255
names: Function
names: Similarity
messages: Belongs to the GlnE family.
messages: Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell.

365046:RTA RS14450
gene id: 365046:RTA_RS14450
uniprot id: F5Y5P1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

365046:RTA RS13760
gene id: 365046:RTA_RS13760
uniprot id: F5Y4E4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell inner membrane
messages: Membrane

365046:RTA RS15450
gene id: 365046:RTA_RS15450
uniprot id: F5XW26
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

365046:RTA RS06200
gene id: 365046:RTA_RS06200
uniprot id: F5Y1P6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

365046:RTA RS00380
gene id: 365046:RTA_RS00380
uniprot id: F5Y2G5
names: Function
names: Similarity
messages: Belongs to the ParB family.
messages: Involved in chromosome partition. Localize to both poles of the predivisional cell following completion of DNA replication. Binds to the DNA origin of replication.

365046:RTA RS08945
gene id: 365046:RTA_RS08945
uniprot id: F5XVS1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

365046:RTA RS08540
gene id: 365046:RTA_RS08540
uniprot id: F5Y669
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

365046:RTA RS19100
gene id: 365046:RTA_RS19100
uniprot id: F5Y281
names: Similarity
messages: Belongs to the N-Me-Phe pilin family.

365046:RTA RS11025
gene id: 365046:RTA_RS11025
uniprot id: F5XZ79
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

365046:RTA RS08490
gene id: 365046:RTA_RS08490
uniprot id: F5Y659
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

365046:RTA RS10990
gene id: 365046:RTA_RS10990
uniprot id: F5XZ72
names: Similarity
messages: Belongs to the AHA1 family.

365046:RTA RS01665
gene id: 365046:RTA_RS01665
uniprot id: F5Y593
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

365046:RTA RS10835
gene id: 365046:RTA_RS10835
uniprot id: F5XZ41
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein L14 (rplN).

365046:RTA RS05455
gene id: 365046:RTA_RS05455
uniprot id: F5Y0C8
names: Similarity
messages: Belongs to the ArsC family.

365046:RTA RS07765
gene id: 365046:RTA_RS07765
uniprot id: F5Y4V1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbB/TolQ family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

365046:RTA RS16030
gene id: 365046:RTA_RS16030
uniprot id: F5XXB0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

365046:RTA RS17020
gene id: 365046:RTA_RS17020
uniprot id: F5XYS4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

365046:RTA RS11035
gene id: 365046:RTA_RS11035
uniprot id: F5XZ81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

365046:RTA RS19515
gene id: 365046:RTA_RS19515
uniprot id: F5Y352
names: Similarity
messages: Belongs to the SIS family. GutQ/KpsF subfamily.

365046:RTA RS14935
gene id: 365046:RTA_RS14935
uniprot id: F5Y6E6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

365046:RTA RS19330
gene id: 365046:RTA_RS19330
uniprot id: F5Y315
names: Similarity
messages: Belongs to the peptidase M24B family.

365046:RTA RS17900
gene id: 365046:RTA_RS17900
uniprot id: F5Y064
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

365046:RTA RS16975
gene id: 365046:RTA_RS16975
uniprot id: F5XYR6
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

365046:RTA RS00230
gene id: 365046:RTA_RS00230
uniprot id: F5Y2D3
names: Subcellular Location Annotation
messages: Membrane

365046:RTA RS19360
gene id: 365046:RTA_RS19360
uniprot id: F5Y320
names: Similarity
messages: Belongs to the malic enzymes family.
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the malic enzymes family.

365046:RTA RS10040
gene id: 365046:RTA_RS10040
uniprot id: F5XXR3
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

365046:RTA RS11595
gene id: 365046:RTA_RS11595
uniprot id: F5Y0F5
names: Similarity
messages: Belongs to the PAPS reductase family. CysD subfamily.

365046:RTA RS18590
gene id: 365046:RTA_RS18590
uniprot id: F5Y1G2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

365046:RTA RS18490
gene id: 365046:RTA_RS18490
uniprot id: F5Y1E2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell inner membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

365046:RTA RS12870
gene id: 365046:RTA_RS12870
uniprot id: F5Y2R7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

365046:RTA RS01925
gene id: 365046:RTA_RS01925
uniprot id: F5Y5E4
names: Function
names: Similarity
messages: Belongs to the MreC family.
messages: Involved in formation and maintenance of cell shape.

365046:RTA RS15415
gene id: 365046:RTA_RS15415
uniprot id: F5XW19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

365046:RTA RS01570
gene id: 365046:RTA_RS01570
uniprot id: F5Y4R6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

365046:RTA RS18730
gene id: 365046:RTA_RS18730
uniprot id: F5Y1J0
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

365046:RTA RS10945
gene id: 365046:RTA_RS10945
uniprot id: F5XZ63
names: Similarity
messages: Belongs to the CcdB toxin family.

365046:RTA RS14820
gene id: 365046:RTA_RS14820
uniprot id: F5Y6C4
names: Similarity
messages: In the N-terminal section; belongs to the phytochrome family.

365046:RTA RS10010
gene id: 365046:RTA_RS10010
uniprot id: F5XX98
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

365046:RTA RS03440
gene id: 365046:RTA_RS03440
uniprot id: F5XWY9
names: Similarity
messages: Belongs to the leucine-binding protein family.

365046:RTA RS01675
gene id: 365046:RTA_RS01675
uniprot id: F5Y595
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

365046:RTA RS18555
gene id: 365046:RTA_RS18555
uniprot id: F5Y1F5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family.
messages: Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
messages: Cell inner membrane

365046:RTA RS07585
gene id: 365046:RTA_RS07585
uniprot id: F5Y4A7
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit A family.

365046:RTA RS12470
gene id: 365046:RTA_RS12470
uniprot id: F5Y1V0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

365046:RTA RS06225
gene id: 365046:RTA_RS06225
uniprot id: F5Y1Q1
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

365046:RTA RS17050
gene id: 365046:RTA_RS17050
uniprot id: F5XYT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

365046:RTA RS02545
gene id: 365046:RTA_RS02545
uniprot id: F5XVK3
names: Similarity
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.

365046:RTA RS09730
gene id: 365046:RTA_RS09730
uniprot id: F5XX44
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamB family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

365046:RTA RS12410
gene id: 365046:RTA_RS12410
uniprot id: F5Y1T9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

365046:RTA RS19450
gene id: 365046:RTA_RS19450
uniprot id: F5Y339
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

365046:RTA RS10880
gene id: 365046:RTA_RS10880
uniprot id: F5XZ50
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

365046:RTA RS00715
gene id: 365046:RTA_RS00715
uniprot id: F5Y3C5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

365046:RTA RS04150
gene id: 365046:RTA_RS04150
uniprot id: F5XY98
names: Similarity
messages: Belongs to the glutamate synthase family.

365046:RTA RS04475
gene id: 365046:RTA_RS04475
uniprot id: F5XYW7
names: Similarity
messages: Belongs to the ABC transporter superfamily.

365046:RTA RS16135
gene id: 365046:RTA_RS16135
uniprot id: F5XXD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

365046:RTA RS05405
gene id: 365046:RTA_RS05405
uniprot id: F5Y0B8
names: Subcellular Location Annotation
messages: Membrane

365046:RTA RS12040
gene id: 365046:RTA_RS12040
uniprot id: F5Y149
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Membrane

365046:RTA RS15745
gene id: 365046:RTA_RS15745
uniprot id: F5XWP4
names: Similarity
messages: Belongs to the peptidase S41A family.

365046:RTA RS08475
gene id: 365046:RTA_RS08475
uniprot id: F5Y656
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

365046:RTA RS17200
gene id: 365046:RTA_RS17200
uniprot id: F5XZB9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoH subfamily.
messages: Cytoplasm
messages: Interacts with the RNA polymerase core enzyme.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.

365046:RTA RS06190
gene id: 365046:RTA_RS06190
uniprot id: F5Y1P4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

365046:RTA RS09435
gene id: 365046:RTA_RS09435
uniprot id: F5XWH7
names: Function
names: Similarity
messages: Belongs to the heat shock protein 70 family.
messages: Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB.

365046:RTA RS14115
gene id: 365046:RTA_RS14115
uniprot id: F5Y521
names: Similarity
messages: Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily.

365046:RTA RS16160
gene id: 365046:RTA_RS16160
uniprot id: F5XXD7
names: Subcellular Location Annotation
messages: Membrane

365046:RTA RS02900
gene id: 365046:RTA_RS02900
uniprot id: F5XW75
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

365046:RTA RS05895
gene id: 365046:RTA_RS05895
uniprot id: F5Y118
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

365046:RTA RS16970
gene id: 365046:RTA_RS16970
uniprot id: F5XYR5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

365046:RTA RS03955
gene id: 365046:RTA_RS03955
uniprot id: F5XXQ1
names: Similarity
messages: Belongs to the UDP-glycosyltransferase family.

365046:RTA RS02920
gene id: 365046:RTA_RS02920
uniprot id: F5XW79
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

365046:RTA RS07640
gene id: 365046:RTA_RS07640
uniprot id: F5Y4S7
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

365046:RTA RS04125
gene id: 365046:RTA_RS04125
uniprot id: F5XY93
names: Subcellular Location Annotation
messages: Membrane

365046:RTA RS01165
gene id: 365046:RTA_RS01165
uniprot id: F5Y423
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

365046:RTA RS05900
gene id: 365046:RTA_RS05900
uniprot id: F5Y119
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

365046:RTA RS01945
gene id: 365046:RTA_RS01945
uniprot id: F5Y5E8
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

365046:RTA RS07870
gene id: 365046:RTA_RS07870
uniprot id: F5Y4X2
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

365046:RTA RS03810
gene id: 365046:RTA_RS03810
uniprot id: F5XXM2
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

365046:RTA RS04875
gene id: 365046:RTA_RS04875
uniprot id: F5XZK8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

365046:RTA RS16325
gene id: 365046:RTA_RS16325
uniprot id: F5XXH0
names: Similarity
messages: Belongs to the GSP E family.

365046:RTA RS21235
gene id: 365046:RTA_RS21235
uniprot id: F5Y3N6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

365046:RTA RS18925
gene id: 365046:RTA_RS18925
uniprot id: F5Y246
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YajC family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the SecDF-YidC-YajC translocase complex. The SecDF-YidC-YajC translocase forms a supercomplex with SecYEG, called the holo-translocon (HTL).
messages: The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions.

365046:RTA RS03645
gene id: 365046:RTA_RS03645
uniprot id: F5XXI9
names: Similarity
messages: Belongs to the PhoH family.

365046:RTA RS03460
gene id: 365046:RTA_RS03460
uniprot id: F5XWZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

365046:RTA RS15655
gene id: 365046:RTA_RS15655
uniprot id: F5XWM6
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

365046:RTA RS03590
gene id: 365046:RTA_RS03590
uniprot id: F5XX20
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

365046:RTA RS08555
gene id: 365046:RTA_RS08555
uniprot id: F5Y672
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

365046:RTA RS18875
gene id: 365046:RTA_RS18875
uniprot id: F5Y236
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

365046:RTA RS00840
gene id: 365046:RTA_RS00840
uniprot id: F5Y3V8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

365046:RTA RS13920
gene id: 365046:RTA_RS13920
uniprot id: F5Y4H7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

365046:RTA RS10310
gene id: 365046:RTA_RS10310
uniprot id: F5XXW7
names: Subcellular Location Annotation
messages: Membrane

365046:RTA RS00675
gene id: 365046:RTA_RS00675
uniprot id: F5Y3B7
names: Subcellular Location Annotation
messages: Membrane

365046:RTA RS10060
gene id: 365046:RTA_RS10060
uniprot id: F5XXR7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

365046:RTA RS00880
gene id: 365046:RTA_RS00880
uniprot id: F5Y3W6
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

365046:RTA RS04310
gene id: 365046:RTA_RS04310
uniprot id: F5XYD0
names: Cofactor
names: Function
names: Miscellaneous
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The Rieske protein is a high potential 2Fe-2S protein.
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

365046:RTA RS13685
gene id: 365046:RTA_RS13685
uniprot id: F5Y4C9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

365046:RTA RS12835
gene id: 365046:RTA_RS12835
uniprot id: F5Y2R0
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

365046:RTA RS14545
gene id: 365046:RTA_RS14545
uniprot id: F5Y5R0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

365046:RTA RS00705
gene id: 365046:RTA_RS00705
uniprot id: F5Y3C3
names: Similarity
messages: Belongs to the asparaginase 1 family.

365046:RTA RS14960
gene id: 365046:RTA_RS14960
uniprot id: F5Y6F2
names: Subcellular Location Annotation
messages: Membrane

365046:RTA RS06705
gene id: 365046:RTA_RS06705
uniprot id: F5Y2N4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

365046:RTA RS10845
gene id: 365046:RTA_RS10845
uniprot id: F5XZ43
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the aerobic coproporphyrinogen-III oxidase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.

365046:RTA RS05105
gene id: 365046:RTA_RS05105
uniprot id: F5XZQ4
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

365046:RTA RS00355
gene id: 365046:RTA_RS00355
uniprot id: F5Y2G0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

365046:RTA RS02625
gene id: 365046:RTA_RS02625
uniprot id: F5XVL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

365046:RTA RS01695
gene id: 365046:RTA_RS01695
uniprot id: F5Y599
names: PTM
messages: Binds 1 heme group per subunit.

365046:RTA RS18860
gene id: 365046:RTA_RS18860
uniprot id: F5Y233
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

365046:RTA RS14415
gene id: 365046:RTA_RS14415
uniprot id: F5Y5N4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

365046:RTA RS06755
gene id: 365046:RTA_RS06755
uniprot id: F5Y2P3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

365046:RTA RS10180
gene id: 365046:RTA_RS10180
uniprot id: F5XXU1
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

365046:RTA RS17675
gene id: 365046:RTA_RS17675
uniprot id: F5Y019
names: Function
names: Similarity
messages: Belongs to the histone H1/H5 family. HCT subfamily.
messages: Might have a role in establishing the nucleoid structure of elementary bodies.

365046:RTA RS04415
gene id: 365046:RTA_RS04415
uniprot id: F5XYV5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

365046:RTA RS17975
gene id: 365046:RTA_RS17975
uniprot id: F5Y0N4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

365046:RTA RS03150
gene id: 365046:RTA_RS03150
uniprot id: F5XWC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

365046:RTA RS17740
gene id: 365046:RTA_RS17740
uniprot id: F5Y032
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response.
messages: Belongs to the SrkA/RdoA protein kinase family.
messages: Cytoplasm
messages: Monomer.

365046:RTA RS03190
gene id: 365046:RTA_RS03190
uniprot id: F5XWU2
names: Subcellular Location Annotation
messages: Membrane

365046:RTA RS10570
gene id: 365046:RTA_RS10570
uniprot id: F5XYI1
names: Similarity
messages: Belongs to the peptidase C56 family.

365046:RTA RS04195
gene id: 365046:RTA_RS04195
uniprot id: F5XYA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

365046:RTA RS04605
gene id: 365046:RTA_RS04605
uniprot id: F5XYZ6
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.

365046:RTA RS12750
gene id: 365046:RTA_RS12750
uniprot id: F5Y205
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

365046:RTA RS15595
gene id: 365046:RTA_RS15595
uniprot id: F5XWL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the formate dehydrogenase gamma subunit family.
messages: Membrane

365046:RTA RS02465
gene id: 365046:RTA_RS02465
uniprot id: F5XVI7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

365046:RTA RS05485
gene id: 365046:RTA_RS05485
uniprot id: F5Y0D4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

365046:RTA RS09505
gene id: 365046:RTA_RS09505
uniprot id: F5XWJ1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

365046:RTA RS07615
gene id: 365046:RTA_RS07615
uniprot id: F5Y4S2
names: Subcellular Location Annotation
messages: Membrane

365046:RTA RS11655
gene id: 365046:RTA_RS11655
uniprot id: F5Y0G7
names: Similarity
messages: Belongs to the LuxC family.

365046:RTA RS16165
gene id: 365046:RTA_RS16165
uniprot id: F5XXD8
names: Function
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.
messages: DNA-dependent ATPase that plays important roles in cellular responses to stalled DNA replication processes.

365046:RTA RS03540
gene id: 365046:RTA_RS03540
uniprot id: F5XX10
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

365046:RTA RS04980
gene id: 365046:RTA_RS04980
uniprot id: F5XZM9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell inner membrane
messages: Self-interacts. Interacts with FtsZ.

365046:RTA RS07885
gene id: 365046:RTA_RS07885
uniprot id: F5Y4X5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

365046:RTA RS08150
gene id: 365046:RTA_RS08150
uniprot id: F5Y5I2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

365046:RTA RS02930
gene id: 365046:RTA_RS02930
uniprot id: F5XW81
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrkH potassium transport family.
messages: Cell inner membrane
messages: Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA.
messages: Membrane

365046:RTA RS06820
gene id: 365046:RTA_RS06820
uniprot id: F5Y3E4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

365046:RTA RS09265
gene id: 365046:RTA_RS09265
uniprot id: F5XWE3
names: Similarity
messages: Belongs to the GST superfamily. Zeta family.

365046:RTA RS14225
gene id: 365046:RTA_RS14225
uniprot id: F5Y540
names: Function
names: Similarity
messages: Belongs to the HPPK family.
messages: Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.

365046:RTA RS09745
gene id: 365046:RTA_RS09745
uniprot id: F5XX47
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

365046:RTA RS05375
gene id: 365046:RTA_RS05375
uniprot id: F5Y0B3
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

365046:RTA RS09430
gene id: 365046:RTA_RS09430
uniprot id: F5XWH6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HscB family.
messages: Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA.
messages: Interacts with HscA and stimulates its ATPase activity.

365046:RTA RS19465
gene id: 365046:RTA_RS19465
uniprot id: F5Y342
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine.

365046:RTA RS12715
gene id: 365046:RTA_RS12715
uniprot id: F5Y1Z8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

365046:RTA RS06825
gene id: 365046:RTA_RS06825
uniprot id: F5Y3E5
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

365046:RTA RS01150
gene id: 365046:RTA_RS01150
uniprot id: F5Y420
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

365046:RTA RS13650
gene id: 365046:RTA_RS13650
uniprot id: F5Y4C2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

365046:RTA RS14230
gene id: 365046:RTA_RS14230
uniprot id: F5Y541
names: Function
names: Similarity
messages: Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

365046:RTA RS10915
gene id: 365046:RTA_RS10915
uniprot id: F5XZ57
names: Subcellular Location Annotation
messages: Membrane

365046:RTA RS05255
gene id: 365046:RTA_RS05255
uniprot id: F5Y091
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Cell membrane
messages: Membrane

365046:RTA RS10125
gene id: 365046:RTA_RS10125
uniprot id: F5XXT0
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

365046:RTA RS15825
gene id: 365046:RTA_RS15825
uniprot id: F5XWR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

365046:RTA RS07220
gene id: 365046:RTA_RS07220
uniprot id: F5Y432
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

365046:RTA RS18790
gene id: 365046:RTA_RS18790
uniprot id: F5Y219
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

365046:RTA RS17190
gene id: 365046:RTA_RS17190
uniprot id: F5XZB7
names: Similarity
messages: Belongs to the CutA family.

365046:RTA RS10510
gene id: 365046:RTA_RS10510
uniprot id: F5XYG9
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Belongs to the peroxiredoxin family. Prx6 subfamily.

365046:RTA RS17615
gene id: 365046:RTA_RS17615
uniprot id: F5Y007
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OpgD/OpgG family.
messages: Periplasm

365046:RTA RS17220
gene id: 365046:RTA_RS17220
uniprot id: F5XZC2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell inner membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: Membrane

365046:RTA RS01660
gene id: 365046:RTA_RS01660
uniprot id: F5Y592
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

365046:RTA RS18660
gene id: 365046:RTA_RS18660
uniprot id: F5Y1H6
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

365046:RTA RS11615
gene id: 365046:RTA_RS11615
uniprot id: F5Y0F9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

365046:RTA RS15530
gene id: 365046:RTA_RS15530
uniprot id: F5XW42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

365046:RTA RS18770
gene id: 365046:RTA_RS18770
uniprot id: F5Y215
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.

365046:RTA RS05875
gene id: 365046:RTA_RS05875
uniprot id: F5Y114
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

365046:RTA RS03045
gene id: 365046:RTA_RS03045
uniprot id: F5XWA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

365046:RTA RS13195
gene id: 365046:RTA_RS13195
uniprot id: F5Y3M2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

365046:RTA RS19505
gene id: 365046:RTA_RS19505
uniprot id: F5Y350
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

365046:RTA RS04970
gene id: 365046:RTA_RS04970
uniprot id: F5XZM7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

365046:RTA RS07255
gene id: 365046:RTA_RS07255
uniprot id: F5Y439
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

365046:RTA RS03105
gene id: 365046:RTA_RS03105
uniprot id: F5XWB6
names: Function
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia.

365046:RTA RS00100
gene id: 365046:RTA_RS00100
uniprot id: F5Y2A8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

365046:RTA RS04220
gene id: 365046:RTA_RS04220
uniprot id: F5XYB2
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

365046:RTA RS16715
gene id: 365046:RTA_RS16715
uniprot id: F5XY59
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UreD family.
messages: Cytoplasm
messages: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
messages: UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

365046:RTA RS15930
gene id: 365046:RTA_RS15930
uniprot id: F5XWT1
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

365046:RTA RS07525
gene id: 365046:RTA_RS07525
uniprot id: F5Y496
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

365046:RTA RS01760
gene id: 365046:RTA_RS01760
uniprot id: F5Y5B2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

365046:RTA RS00265
gene id: 365046:RTA_RS00265
uniprot id: F5Y2E1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

365046:RTA RS02385
gene id: 365046:RTA_RS02385
uniprot id: F5XVH1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

365046:RTA RS09740
gene id: 365046:RTA_RS09740
uniprot id: F5XX46
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

365046:RTA RS01915
gene id: 365046:RTA_RS01915
uniprot id: F5Y5E2
names: Function
names: Similarity
messages: Belongs to the transpeptidase family. MrdA subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall.

365046:RTA RS19255
gene id: 365046:RTA_RS19255
uniprot id: F5Y300
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

365046:RTA RS13495
gene id: 365046:RTA_RS13495
uniprot id: F5Y3T2
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

365046:RTA RS01400
gene id: 365046:RTA_RS01400
uniprot id: F5Y4N0
names: Function
names: Similarity
messages: Belongs to the sigma-54 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

365046:RTA RS13465
gene id: 365046:RTA_RS13465
uniprot id: F5Y3S6
names: Subcellular Location Annotation
messages: Membrane

365046:RTA RS19105
gene id: 365046:RTA_RS19105
uniprot id: F5Y282
names: Similarity
messages: Belongs to the GSP E family.

365046:RTA RS12370
gene id: 365046:RTA_RS12370
uniprot id: F5Y1B4
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

365046:RTA RS01580
gene id: 365046:RTA_RS01580
uniprot id: F5Y4R8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HemJ family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Catalyzes the oxidation of protoporphyrinogen IX to protoporphyrin IX.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

365046:RTA RS08265
gene id: 365046:RTA_RS08265
uniprot id: F5Y5K5
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.

365046:RTA RS18535
gene id: 365046:RTA_RS18535
uniprot id: F5Y1F1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

365046:RTA RS19260
gene id: 365046:RTA_RS19260
uniprot id: F5Y301
names: Similarity
messages: Belongs to the FAD-binding monooxygenase family.

365046:RTA RS13955
gene id: 365046:RTA_RS13955
uniprot id: F5Y4I4
names: Similarity
messages: Belongs to the ACC deaminase/D-cysteine desulfhydrase family.

365046:RTA RS05730
gene id: 365046:RTA_RS05730
uniprot id: F5Y0Y5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

365046:RTA RS15705
gene id: 365046:RTA_RS15705
uniprot id: F5XWN6
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

365046:RTA RS10315
gene id: 365046:RTA_RS10315
uniprot id: F5XXW8
names: Subcellular Location Annotation
messages: Membrane

365046:RTA RS08605
gene id: 365046:RTA_RS08605
uniprot id: F5Y682
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

365046:RTA RS16375
gene id: 365046:RTA_RS16375
uniprot id: F5XXZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family.
messages: Cell inner membrane
messages: Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.
messages: The complex is composed of two ATP-binding proteins (LolD) and two transmembrane proteins (LolC and LolE).

365046:RTA RS07520
gene id: 365046:RTA_RS07520
uniprot id: F5Y495
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

365046:RTA RS19310
gene id: 365046:RTA_RS19310
uniprot id: F5Y311
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

365046:RTA RS16600
gene id: 365046:RTA_RS16600
uniprot id: F5XY36
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

365046:RTA RS18025
gene id: 365046:RTA_RS18025
uniprot id: F5Y0P4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

365046:RTA RS15725
gene id: 365046:RTA_RS15725
uniprot id: F5XWP0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecB family.
messages: Cytoplasm
messages: Homotetramer, a dimer of dimers. One homotetramer interacts with 1 SecA dimer.
messages: One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.

365046:RTA RS09065
gene id: 365046:RTA_RS09065
uniprot id: F5XVU4
names: Subcellular Location Annotation
messages: Membrane

365046:RTA RS18495
gene id: 365046:RTA_RS18495
uniprot id: F5Y1E3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

365046:RTA RS05020
gene id: 365046:RTA_RS05020
uniprot id: F5XZN8
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

365046:RTA RS02540
gene id: 365046:RTA_RS02540
uniprot id: F5XVK2
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

365046:RTA RS08435
gene id: 365046:RTA_RS08435
uniprot id: F5Y648
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Cob(I)alamin adenosyltransferase family.
messages: Cytoplasm
messages: Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids.

365046:RTA RS13945
gene id: 365046:RTA_RS13945
uniprot id: F5Y4I2
names: Cofactor
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.

365046:RTA RS13550
gene id: 365046:RTA_RS13550
uniprot id: F5Y3U2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

365046:RTA RS06520
gene id: 365046:RTA_RS06520
uniprot id: F5Y2J9
names: Function
names: Similarity
messages: Belongs to the IMPDH/GMPR family. GuaC type 2 subfamily.
messages: Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.

365046:RTA RS12405
gene id: 365046:RTA_RS12405
uniprot id: F5Y1T8
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

365046:RTA RS13245
gene id: 365046:RTA_RS13245
uniprot id: F5Y3N2
names: Similarity
messages: Belongs to the universal stress protein A family.

365046:RTA RS14595
gene id: 365046:RTA_RS14595
uniprot id: F5Y5S0
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

365046:RTA RS09380
gene id: 365046:RTA_RS09380
uniprot id: F5XWG6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

365046:RTA RS01575
gene id: 365046:RTA_RS01575
uniprot id: F5Y4R7
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

365046:RTA RS10090
gene id: 365046:RTA_RS10090
uniprot id: F5XXS3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

365046:RTA RS05345
gene id: 365046:RTA_RS05345
uniprot id: F5Y0A7
names: Similarity
messages: Belongs to the FPG family.

365046:RTA RS09845
gene id: 365046:RTA_RS09845
uniprot id: F5XX67
names: Similarity
messages: Belongs to the UPF0311 family.

365046:RTA RS04000
gene id: 365046:RTA_RS04000
uniprot id: F5XY70
names: Subcellular Location Annotation
messages: Membrane

365046:RTA RS04070
gene id: 365046:RTA_RS04070
uniprot id: F5XY82
names: Function
names: Similarity
messages: Belongs to the frataxin family.
messages: Involved in iron-sulfur (Fe-S) cluster assembly. May act as a regulator of Fe-S biogenesis.

365046:RTA RS17775
gene id: 365046:RTA_RS17775
uniprot id: F5Y039
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

365046:RTA RS08185
gene id: 365046:RTA_RS08185
uniprot id: F5Y5I9
names: Caution
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

365046:RTA RS18905
gene id: 365046:RTA_RS18905
uniprot id: F5Y242
names: Similarity
messages: Belongs to the Smg family.

365046:RTA RS18280
gene id: 365046:RTA_RS18280
uniprot id: F5Y0U5
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

365046:RTA RS16605
gene id: 365046:RTA_RS16605
uniprot id: F5XY37
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

365046:RTA RS12060
gene id: 365046:RTA_RS12060
uniprot id: F5Y153
names: Similarity
messages: Belongs to the GppA/Ppx family.

365046:RTA RS18985
gene id: 365046:RTA_RS18985
uniprot id: F5Y258
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

365046:RTA RS02890
gene id: 365046:RTA_RS02890
uniprot id: F5XW73
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AceK family.
messages: Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation.
messages: Cytoplasm

365046:RTA RS04890
gene id: 365046:RTA_RS04890
uniprot id: F5XZL1
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

365046:RTA RS16645
gene id: 365046:RTA_RS16645
uniprot id: F5XY45
names: Similarity
messages: Belongs to the UPF0047 family.

365046:RTA RS00435
gene id: 365046:RTA_RS00435
uniprot id: F5Y363
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

365046:RTA RS15255
gene id: 365046:RTA_RS15255
uniprot id: F5XVY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Membrane

365046:RTA RS01635
gene id: 365046:RTA_RS01635
uniprot id: F5Y587
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

365046:RTA RS01805
gene id: 365046:RTA_RS01805
uniprot id: F5Y5C1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

365046:RTA RS10500
gene id: 365046:RTA_RS10500
uniprot id: F5XYG7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import.
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

365046:RTA RS13480
gene id: 365046:RTA_RS13480
uniprot id: F5Y3S9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

365046:RTA RS12305
gene id: 365046:RTA_RS12305
uniprot id: F5Y1A1
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

365046:RTA RS12865
gene id: 365046:RTA_RS12865
uniprot id: F5Y2R6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

365046:RTA RS02665
gene id: 365046:RTA_RS02665
uniprot id: F5XVM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Cytoplasm

365046:RTA RS09045
gene id: 365046:RTA_RS09045
uniprot id: F5XVU0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
messages: Cytoplasm
messages: Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.

365046:RTA RS18800
gene id: 365046:RTA_RS18800
uniprot id: F5Y221
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.

365046:RTA RS10055
gene id: 365046:RTA_RS10055
uniprot id: F5XXR6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

365046:RTA RS14835
gene id: 365046:RTA_RS14835
uniprot id: F5Y6C7
names: Similarity
messages: Belongs to the UPF0246 family.

365046:RTA RS18560
gene id: 365046:RTA_RS18560
uniprot id: F5Y1F6
names: Similarity
messages: Belongs to the Dps family.

365046:RTA RS03770
gene id: 365046:RTA_RS03770
uniprot id: F5XXL4
names: Cofactor
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A single active site specifically recognizes both ATP and CTP and is responsible for their addition.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 1 subfamily.
messages: Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases.
messages: Comprises two domains: an N-terminal domain containing the nucleotidyltransferase activity and a C-terminal HD domain associated with both phosphodiesterase and phosphatase activities.
messages: Magnesium is required for nucleotidyltransferase activity.
messages: Monomer. Can also form homodimers and oligomers.
messages: Nickel for phosphatase activity.

365046:RTA RS07775
gene id: 365046:RTA_RS07775
uniprot id: F5Y4V3
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

365046:RTA RS08705
gene id: 365046:RTA_RS08705
uniprot id: F5Y6A1
names: Similarity
messages: Belongs to the DODA-type extradiol aromatic ring-opening dioxygenase family.

365046:RTA RS10505
gene id: 365046:RTA_RS10505
uniprot id: F5XYG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic sulfate-binding protein family.
messages: Periplasm

365046:RTA RS11285
gene id: 365046:RTA_RS11285
uniprot id: F5XZU0
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

365046:RTA RS06015
gene id: 365046:RTA_RS06015
uniprot id: F5Y1L0
names: Subcellular Location Annotation
messages: Membrane

365046:RTA RS18255
gene id: 365046:RTA_RS18255
uniprot id: F5Y0U0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

365046:RTA RS09850
gene id: 365046:RTA_RS09850
uniprot id: F5XX68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

365046:RTA RS00215
gene id: 365046:RTA_RS00215
uniprot id: F5Y2D0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PagL family.
messages: Cell outer membrane
messages: Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety.
messages: Homodimer.

365046:RTA RS11840
gene id: 365046:RTA_RS11840
uniprot id: F5Y0K4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

365046:RTA RS11755
gene id: 365046:RTA_RS11755
uniprot id: F5Y0I7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

365046:RTA RS01075
gene id: 365046:RTA_RS01075
uniprot id: F5Y405
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

365046:RTA RS04925
gene id: 365046:RTA_RS04925
uniprot id: F5XZL8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsL family.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
messages: Membrane
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

365046:RTA RS21230
gene id: 365046:RTA_RS21230
uniprot id: F5Y3N5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

365046:RTA RS04955
gene id: 365046:RTA_RS04955
uniprot id: F5XZM4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. FtsW subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell division.

365046:RTA RS07105
gene id: 365046:RTA_RS07105
uniprot id: F5Y3K0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

365046:RTA RS04245
gene id: 365046:RTA_RS04245
uniprot id: F5XYB7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

365046:RTA RS05435
gene id: 365046:RTA_RS05435
uniprot id: F5Y0C4
names: Function
names: Similarity
messages: Belongs to the nucleoside phosphorylase PpnP family.
messages: Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions.

365046:RTA RS05160
gene id: 365046:RTA_RS05160
uniprot id: F5XZR5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

365046:RTA RS04325
gene id: 365046:RTA_RS04325
uniprot id: F5XYD3
names: Similarity
messages: Belongs to the GST superfamily. HSP26 family.

365046:RTA RS00160
gene id: 365046:RTA_RS00160
uniprot id: F5Y2B9
names: Similarity
messages: Belongs to the AHA1 family.

365046:RTA RS16745
gene id: 365046:RTA_RS16745
uniprot id: F5XY64
names: Subcellular Location Annotation
messages: Membrane

365046:RTA RS02610
gene id: 365046:RTA_RS02610
uniprot id: F5XVL6
names: Function
names: Subunit
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
messages: Homodimer. Part of the PDH complex, consisting of multiple copies of pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

365046:RTA RS05755
gene id: 365046:RTA_RS05755
uniprot id: F5Y0Z0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Nucleus

365046:RTA RS05415
gene id: 365046:RTA_RS05415
uniprot id: F5Y0C0
names: Similarity
messages: Belongs to the UPF0234 family.

365046:RTA RS18835
gene id: 365046:RTA_RS18835
uniprot id: F5Y228
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

365046:RTA RS08940
gene id: 365046:RTA_RS08940
uniprot id: F5XVS0
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

365046:RTA RS06310
gene id: 365046:RTA_RS06310
uniprot id: F5Y1R8
names: Similarity
messages: Belongs to the PilY1 family.

365046:RTA RS00590
gene id: 365046:RTA_RS00590
uniprot id: F5Y399
names: Similarity
messages: Belongs to the universal stress protein A family.

365046:RTA RS03415
gene id: 365046:RTA_RS03415
uniprot id: F5XWY4
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

365046:RTA RS00400
gene id: 365046:RTA_RS00400
uniprot id: F5Y2G9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

365046:RTA RS00170
gene id: 365046:RTA_RS00170
uniprot id: F5Y2C1
names: Function
names: Similarity
names: Subunit
messages: ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.
messages: Belongs to the ParA family. MinD subfamily.
messages: Interacts with MinC and FtsZ.

365046:RTA RS05320
gene id: 365046:RTA_RS05320
uniprot id: F5Y0A2
names: Similarity
messages: Belongs to the peptidase M1 family.

365046:RTA RS14770
gene id: 365046:RTA_RS14770
uniprot id: F5Y5V4
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

365046:RTA RS09770
gene id: 365046:RTA_RS09770
uniprot id: F5XX52
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

365046:RTA RS07690
gene id: 365046:RTA_RS07690
uniprot id: F5Y4T6
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

365046:RTA RS12000
gene id: 365046:RTA_RS12000
uniprot id: F5Y141
names: Similarity
messages: Belongs to the Dps family.

365046:RTA RS04815
gene id: 365046:RTA_RS04815
uniprot id: F5XZJ6
names: Similarity
messages: Belongs to the ABC transporter superfamily.

365046:RTA RS17170
gene id: 365046:RTA_RS17170
uniprot id: F5XZB3
names: Similarity
messages: Belongs to the phosphate/phosphite/phosphonate binding protein family.

365046:RTA RS15950
gene id: 365046:RTA_RS15950
uniprot id: F5XWT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

365046:RTA RS17670
gene id: 365046:RTA_RS17670
uniprot id: F5Y018
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

365046:RTA RS13365
gene id: 365046:RTA_RS13365
uniprot id: F5Y3Q6
names: Subcellular Location Annotation
messages: Membrane

365046:RTA RS14520
gene id: 365046:RTA_RS14520
uniprot id: F5Y5Q5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 3 family. NagZ subfamily.
messages: Cytoplasm
messages: Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides.

365046:RTA RS16420
gene id: 365046:RTA_RS16420
uniprot id: F5XXZ9
names: Subcellular Location Annotation
messages: Membrane

365046:RTA RS12295
gene id: 365046:RTA_RS12295
uniprot id: F5Y199
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

365046:RTA RS00175
gene id: 365046:RTA_RS00175
uniprot id: F5Y2C2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MinC family.
messages: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.
messages: Interacts with MinD and FtsZ.

365046:RTA RS18100
gene id: 365046:RTA_RS18100
uniprot id: F5Y0Q9
names: Similarity
messages: Belongs to the GSP N family.

365046:RTA RS04225
gene id: 365046:RTA_RS04225
uniprot id: F5XYB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

365046:RTA RS09755
gene id: 365046:RTA_RS09755
uniprot id: F5XX49
names: Function
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflC subfamily.
messages: HflC and HflK could regulate a protease.

365046:RTA RS10750
gene id: 365046:RTA_RS10750
uniprot id: F5XYL9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M20A family. DapE subfamily.
messages: Binds 2 Zn(2+) or Co(2+) ions per subunit.
messages: Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
messages: Homodimer.

365046:RTA RS00205
gene id: 365046:RTA_RS00205
uniprot id: F5Y2C8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase D family. Cardiolipin synthase subfamily. ClsB sub-subfamily.
messages: Catalyzes the phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
messages: Cell membrane

365046:RTA RS14620
gene id: 365046:RTA_RS14620
uniprot id: F5Y5S5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

365046:RTA RS01190
gene id: 365046:RTA_RS01190
uniprot id: F5Y428
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
messages: Cell inner membrane
messages: Membrane
messages: Transport of potassium into the cell.

365046:RTA RS01555
gene id: 365046:RTA_RS01555
uniprot id: F5Y4R3
names: Similarity
messages: Belongs to the GST superfamily.

365046:RTA RS01375
gene id: 365046:RTA_RS01375
uniprot id: F5Y4M5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

365046:RTA RS05165
gene id: 365046:RTA_RS05165
uniprot id: F5XZR6
names: Caution
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IcmF family.
messages: Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly.
messages: Homodimer.
messages: Is composed of four functional domains: the N-terminal 5'-deoxyadenosylcobalamin binding region that is homologous to the small subunit of ICM (IcmB), a middle P-loop GTPase domain (MeaI) that likely acts as a chaperone for ICM, a structured linker region involved in dimer formation, and a C-terminal part that is homologous to the large substrate-binding subunit of ICM (IcmA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

365046:RTA RS08960
gene id: 365046:RTA_RS08960
uniprot id: F5XVS4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

365046:RTA RS02935
gene id: 365046:RTA_RS02935
uniprot id: F5XW82
names: Similarity
messages: Belongs to the UPF0225 family.

365046:RTA RS07180
gene id: 365046:RTA_RS07180
uniprot id: F5Y3L5
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.

365046:RTA RS06960
gene id: 365046:RTA_RS06960
uniprot id: F5Y3H1
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily.
messages: Binds 1 NADP(+) per subunit.
messages: Catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose.
messages: Contains a large N-terminal NADP-binding domain, and a smaller C-terminal substrate-binding domain.
messages: Homopentamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

365046:RTA RS13800
gene id: 365046:RTA_RS13800
uniprot id: F5Y4F2
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

365046:RTA RS14305
gene id: 365046:RTA_RS14305
uniprot id: F5Y556
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tryptophan 2,3-dioxygenase family.
messages: Binds 1 heme group per subunit.
messages: Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L-tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.
messages: Homotetramer.

365046:RTA RS10810
gene id: 365046:RTA_RS10810
uniprot id: F5XZ36
names: Subcellular Location Annotation
messages: Membrane

365046:RTA RS14475
gene id: 365046:RTA_RS14475
uniprot id: F5Y5P6
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

365046:RTA RS00830
gene id: 365046:RTA_RS00830
uniprot id: F5Y3V6
names: Similarity
messages: Belongs to the ketopantoate reductase family.

365046:RTA RS18565
gene id: 365046:RTA_RS18565
uniprot id: F5Y1F7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

365046:RTA RS13705
gene id: 365046:RTA_RS13705
uniprot id: F5Y4D3
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.

365046:RTA RS17665
gene id: 365046:RTA_RS17665
uniprot id: F5Y017
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

365046:RTA RS01605
gene id: 365046:RTA_RS01605
uniprot id: F5Y581
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

365046:RTA RS14745
gene id: 365046:RTA_RS14745
uniprot id: F5Y5U9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Periplasm

365046:RTA RS03690
gene id: 365046:RTA_RS03690
uniprot id: F5XXJ8
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TtcA family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is chelated by three Cys residues, the fourth Fe has a free coordination site that may bind a sulfur atom transferred from the persulfide of IscS.
messages: Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
messages: Cytoplasm
messages: Homodimer.
messages: The thiolation reaction likely consists of two steps: a first activation step by ATP to form an adenylated intermediate of the target base of tRNA, and a second nucleophilic substitution step of the sulfur (S) atom supplied by the hydrosulfide attached to the Fe-S cluster.

365046:RTA RS04935
gene id: 365046:RTA_RS04935
uniprot id: F5XZM0
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

365046:RTA RS03005
gene id: 365046:RTA_RS03005
uniprot id: F5XW96
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.

365046:RTA RS14625
gene id: 365046:RTA_RS14625
uniprot id: F5Y5S6
names: Function
names: Similarity
messages: Belongs to the DUF177 domain family.
messages: Plays a role in synthesis, processing and/or stability of 23S rRNA.

365046:RTA RS09785
gene id: 365046:RTA_RS09785
uniprot id: F5XX55
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

365046:RTA RS03795
gene id: 365046:RTA_RS03795
uniprot id: F5XXL9
names: Similarity
messages: Belongs to the Gfa family.

365046:RTA RS08950
gene id: 365046:RTA_RS08950
uniprot id: F5XVS2
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

365046:RTA RS08140
gene id: 365046:RTA_RS08140
uniprot id: F5Y5I0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

365046:RTA RS13070
gene id: 365046:RTA_RS13070
uniprot id: F5Y2V6
names: Similarity
messages: Belongs to the YciI family.

365046:RTA RS00310
gene id: 365046:RTA_RS00310
uniprot id: F5Y2F0
names: Similarity
messages: Belongs to the GST superfamily.

365046:RTA RS09025
gene id: 365046:RTA_RS09025
uniprot id: F5XVT7
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

365046:RTA RS14855
gene id: 365046:RTA_RS14855
uniprot id: F5Y6D1
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

365046:RTA RS10775
gene id: 365046:RTA_RS10775
uniprot id: F5XYM3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpoB family.
messages: Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division.
messages: Periplasm

365046:RTA RS04460
gene id: 365046:RTA_RS04460
uniprot id: F5XYW4
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

365046:RTA RS10900
gene id: 365046:RTA_RS10900
uniprot id: F5XZ54
names: Similarity
messages: Belongs to the BMP lipoprotein family.

365046:RTA RS18370
gene id: 365046:RTA_RS18370
uniprot id: F5Y1B9
names: Function
names: Similarity
messages: Belongs to the catalase family.
messages: Serves to protect cells from the toxic effects of hydrogen peroxide.

365046:RTA RS05715
gene id: 365046:RTA_RS05715
uniprot id: F5Y0Y2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

365046:RTA RS01795
gene id: 365046:RTA_RS01795
uniprot id: F5Y5B9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase delta chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

365046:RTA RS07275
gene id: 365046:RTA_RS07275
uniprot id: F5Y443
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

365046:RTA RS10780
gene id: 365046:RTA_RS10780
uniprot id: F5XYM4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Pal lipoprotein family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

365046:RTA RS07380
gene id: 365046:RTA_RS07380
uniprot id: F5Y468
names: Similarity
messages: Belongs to the glutamine synthetase family.

365046:RTA RS04820
gene id: 365046:RTA_RS04820
uniprot id: F5XZJ7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Homodimer.

365046:RTA RS07900
gene id: 365046:RTA_RS07900
uniprot id: F5Y4X8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

365046:RTA RS09320
gene id: 365046:RTA_RS09320
uniprot id: F5XWF4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

365046:RTA RS14535
gene id: 365046:RTA_RS14535
uniprot id: F5Y5Q8
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

365046:RTA RS01035
gene id: 365046:RTA_RS01035
uniprot id: F5Y3Z7
names: Function
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

365046:RTA RS18085
gene id: 365046:RTA_RS18085
uniprot id: F5Y0Q6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP K family.
messages: Cell inner membrane
messages: Membrane

365046:RTA RS17330
gene id: 365046:RTA_RS17330
uniprot id: F5XZE4
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

365046:RTA RS14985
gene id: 365046:RTA_RS14985
uniprot id: F5Y6F7
names: Similarity
messages: Belongs to the HipA Ser/Thr kinase family.

365046:RTA RS00990
gene id: 365046:RTA_RS00990
uniprot id: F5Y3Y8
names: Subcellular Location Annotation
messages: Membrane

365046:RTA RS05980
gene id: 365046:RTA_RS05980
uniprot id: F5Y136
names: Similarity
messages: Belongs to the peptidase S58 family.

365046:RTA RS18880
gene id: 365046:RTA_RS18880
uniprot id: F5Y237
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

365046:RTA RS12395
gene id: 365046:RTA_RS12395
uniprot id: F5Y1T6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

365046:RTA RS15625
gene id: 365046:RTA_RS15625
uniprot id: F5XWM0
names: Subcellular Location Annotation
messages: Membrane

365046:RTA RS13740
gene id: 365046:RTA_RS13740
uniprot id: F5Y4E0
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

365046:RTA RS13510
gene id: 365046:RTA_RS13510
uniprot id: F5Y3T5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 30 kDa subunit family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

365046:RTA RS07320
gene id: 365046:RTA_RS07320
uniprot id: F5Y452
names: Similarity
messages: Belongs to the TPP enzyme family.

365046:RTA RS00915
gene id: 365046:RTA_RS00915
uniprot id: F5Y3X3
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

365046:RTA RS16850
gene id: 365046:RTA_RS16850
uniprot id: F5XYP2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

365046:RTA RS15660
gene id: 365046:RTA_RS15660
uniprot id: F5XWM7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.
messages: In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: In the N-terminal section; belongs to the MIP18 family.

365046:RTA RS08450
gene id: 365046:RTA_RS08450
uniprot id: F5Y651
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.

365046:RTA RS14380
gene id: 365046:RTA_RS14380
uniprot id: F5Y571
names: Cofactor
names: Subunit
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD. The complex can form homotrimers.
messages: The heme is bound between the two transmembrane subunits.

365046:RTA RS01755
gene id: 365046:RTA_RS01755
uniprot id: F5Y5B1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

365046:RTA RS10280
gene id: 365046:RTA_RS10280
uniprot id: F5XXW1
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

365046:RTA RS16775
gene id: 365046:RTA_RS16775
uniprot id: F5XYM8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease gamma subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

365046:RTA RS12455
gene id: 365046:RTA_RS12455
uniprot id: F5Y1U7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

365046:RTA RS03130
gene id: 365046:RTA_RS03130
uniprot id: F5XWC1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

365046:RTA RS09335
gene id: 365046:RTA_RS09335
uniprot id: F5XWF7
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

365046:RTA RS12360
gene id: 365046:RTA_RS12360
uniprot id: F5Y1B2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

365046:RTA RS08240
gene id: 365046:RTA_RS08240
uniprot id: F5Y5K0
names: Similarity
messages: Belongs to the myo-inositol 1-phosphate synthase family.

365046:RTA RS17805
gene id: 365046:RTA_RS17805
uniprot id: F5Y045
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Molecular chaperone. Has ATPase activity.

365046:RTA RS18810
gene id: 365046:RTA_RS18810
uniprot id: F5Y223
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

365046:RTA RS11085
gene id: 365046:RTA_RS11085
uniprot id: F5XZ91
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

365046:RTA RS05180
gene id: 365046:RTA_RS05180
uniprot id: F5XZR9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial solute-binding protein 7 family.
messages: Homodimer.
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: Periplasm

365046:RTA RS09495
gene id: 365046:RTA_RS09495
uniprot id: F5XWI9
names: Subcellular Location Annotation
messages: Membrane

365046:RTA RS09580
gene id: 365046:RTA_RS09580
uniprot id: F5XWK5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 2 lipoyl cofactors covalently.
messages: Forms a 24-polypeptide structural core with octahedral symmetry.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

365046:RTA RS17205
gene id: 365046:RTA_RS17205
uniprot id: F5XZC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

365046:RTA RS17750
gene id: 365046:RTA_RS17750
uniprot id: F5Y034
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated protein Cas5 family. Subtype I-C/Dvulg subfamily.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).

365046:RTA RS08970
gene id: 365046:RTA_RS08970
uniprot id: F5XVS6
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

365046:RTA RS18485
gene id: 365046:RTA_RS18485
uniprot id: F5Y1E1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

365046:RTA RS04835
gene id: 365046:RTA_RS04835
uniprot id: F5XZK0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane
messages: Membrane

365046:RTA RS15265
gene id: 365046:RTA_RS15265
uniprot id: F5XVY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Cytoplasm

365046:RTA RS12330
gene id: 365046:RTA_RS12330
uniprot id: F5Y1A6
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins.

365046:RTA RS10415
gene id: 365046:RTA_RS10415
uniprot id: F5XYF0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: In the N-terminal section; belongs to the FGAMS family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.

365046:RTA RS02835
gene id: 365046:RTA_RS02835
uniprot id: F5XW62
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

365046:RTA RS10635
gene id: 365046:RTA_RS10635
uniprot id: F5XYJ6
names: Similarity
messages: Belongs to the YciI family.

365046:RTA RS12880
gene id: 365046:RTA_RS12880
uniprot id: F5Y2R9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

365046:RTA RS01120
gene id: 365046:RTA_RS01120
uniprot id: F5Y414
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

365046:RTA RS09190
gene id: 365046:RTA_RS09190
uniprot id: F5XVW8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

365046:RTA RS16380
gene id: 365046:RTA_RS16380
uniprot id: F5XXZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

365046:RTA RS13910
gene id: 365046:RTA_RS13910
uniprot id: F5Y4H5
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

365046:RTA RS05065
gene id: 365046:RTA_RS05065
uniprot id: F5XZP7
names: Similarity
messages: Belongs to the peptidase U62 family.

365046:RTA RS00855
gene id: 365046:RTA_RS00855
uniprot id: F5Y3W1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

365046:RTA RS09270
gene id: 365046:RTA_RS09270
uniprot id: F5XWE4
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

365046:RTA RS07315
gene id: 365046:RTA_RS07315
uniprot id: F5Y451
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

365046:RTA RS02280
gene id: 365046:RTA_RS02280
uniprot id: F5Y618
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

365046:RTA RS14385
gene id: 365046:RTA_RS14385
uniprot id: F5Y572
names: Cofactor
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD.
messages: The heme is bound between the two transmembrane subunits.

365046:RTA RS14730
gene id: 365046:RTA_RS14730
uniprot id: F5Y5U6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

365046:RTA RS13410
gene id: 365046:RTA_RS13410
uniprot id: F5Y3R5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of sn-l,2-diacylglycerol (DAG) to phosphatidic acid. Involved in the recycling of diacylglycerol produced as a by-product during membrane-derived oligosaccharide (MDO) biosynthesis.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

365046:RTA RS01650
gene id: 365046:RTA_RS01650
uniprot id: F5Y590
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

365046:RTA RS07785
gene id: 365046:RTA_RS07785
uniprot id: F5Y4V5
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

365046:RTA RS20670
gene id: 365046:RTA_RS20670
uniprot id: F5Y4Y4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

365046:RTA RS06215
gene id: 365046:RTA_RS06215
uniprot id: F5Y1P9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

365046:RTA RS11090
gene id: 365046:RTA_RS11090
uniprot id: F5XZ92
names: Function
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.

365046:RTA RS19285
gene id: 365046:RTA_RS19285
uniprot id: F5Y306
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

365046:RTA RS10360
gene id: 365046:RTA_RS10360
uniprot id: F5XXX8
names: Similarity
messages: Belongs to the BolA/IbaG family.

365046:RTA RS01385
gene id: 365046:RTA_RS01385
uniprot id: F5Y4M7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbA subfamily.
messages: Periplasm

365046:RTA RS15340
gene id: 365046:RTA_RS15340
uniprot id: F5XW01
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

365046:RTA RS14265
gene id: 365046:RTA_RS14265
uniprot id: F5Y548
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

365046:RTA RS14465
gene id: 365046:RTA_RS14465
uniprot id: F5Y5P4
names: Similarity
messages: Belongs to the YggT family.

365046:RTA RS05885
gene id: 365046:RTA_RS05885
uniprot id: F5Y116
names: Similarity
messages: Belongs to the IlvD/Edd family.

365046:RTA RS10420
gene id: 365046:RTA_RS10420
uniprot id: F5XYF1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

365046:RTA RS01235
gene id: 365046:RTA_RS01235
uniprot id: F5Y4J7
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

365046:RTA RS02840
gene id: 365046:RTA_RS02840
uniprot id: F5XW63
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

365046:RTA RS06340
gene id: 365046:RTA_RS06340
uniprot id: F5Y1S4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

365046:RTA RS16245
gene id: 365046:RTA_RS16245
uniprot id: F5XXF4
names: Function
names: Similarity
messages: Belongs to the ribF family.
messages: Catalyzes the phosphorylation of riboflavin to FMN followed by the adenylation of FMN to FAD.

365046:RTA RS05355
gene id: 365046:RTA_RS05355
uniprot id: F5Y0A9
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

365046:RTA RS02095
gene id: 365046:RTA_RS02095
uniprot id: F5Y5Y1
names: Subcellular Location Annotation
messages: Membrane

365046:RTA RS06940
gene id: 365046:RTA_RS06940
uniprot id: F5Y3G7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

365046:RTA RS06355
gene id: 365046:RTA_RS06355
uniprot id: F5Y1S7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

365046:RTA RS01125
gene id: 365046:RTA_RS01125
uniprot id: F5Y415
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

365046:RTA RS10195
gene id: 365046:RTA_RS10195
uniprot id: F5XXU4
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

365046:RTA RS15855
gene id: 365046:RTA_RS15855
uniprot id: F5XWR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

365046:RTA RS11805
gene id: 365046:RTA_RS11805
uniprot id: F5Y0J7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

365046:RTA RS10655
gene id: 365046:RTA_RS10655
uniprot id: F5XYK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

365046:RTA RS03545
gene id: 365046:RTA_RS03545
uniprot id: F5XX11
names: Similarity
messages: Belongs to the TlyA family.

365046:RTA RS14400
gene id: 365046:RTA_RS14400
uniprot id: F5Y575
names: Similarity
messages: Belongs to the SdhE FAD assembly factor family.

365046:RTA RS14660
gene id: 365046:RTA_RS14660
uniprot id: F5Y5T3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase E/G family. RNase E subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per homotetramer.
messages: Cell inner membrane
messages: Cytoplasm
messages: Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs.
messages: Homotetramer formed by a dimer of dimers.

365046:RTA RS07590
gene id: 365046:RTA_RS07590
uniprot id: F5Y4A8
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

365046:RTA RS09945
gene id: 365046:RTA_RS09945
uniprot id: F5XX86
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

365046:RTA RS03930
gene id: 365046:RTA_RS03930
uniprot id: F5XXP6
names: Similarity
messages: Belongs to the sterol desaturase family.

365046:RTA RS18270
gene id: 365046:RTA_RS18270
uniprot id: F5Y0U3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

365046:RTA RS14905
gene id: 365046:RTA_RS14905
uniprot id: F5Y6E1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

365046:RTA RS15650
gene id: 365046:RTA_RS15650
uniprot id: F5XWM5
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

365046:RTA RS01130
gene id: 365046:RTA_RS01130
uniprot id: F5Y416
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

365046:RTA RS19155
gene id: 365046:RTA_RS19155
uniprot id: F5Y292
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

365046:RTA RS16635
gene id: 365046:RTA_RS16635
uniprot id: F5XY43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

365046:RTA RS19520
gene id: 365046:RTA_RS19520
uniprot id: F5Y353
names: Similarity
messages: Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.

365046:RTA RS13500
gene id: 365046:RTA_RS13500
uniprot id: F5Y3T3
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

365046:RTA RS17725
gene id: 365046:RTA_RS17725
uniprot id: F5Y029
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

365046:RTA RS17580
gene id: 365046:RTA_RS17580
uniprot id: F5Y001
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

365046:RTA RS09285
gene id: 365046:RTA_RS09285
uniprot id: F5XWE7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

365046:RTA RS13905
gene id: 365046:RTA_RS13905
uniprot id: F5Y4H4
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

365046:RTA RS04315
gene id: 365046:RTA_RS04315
uniprot id: F5XYD1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b family.
messages: Binds 2 heme groups non-covalently.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

365046:RTA RS08710
gene id: 365046:RTA_RS08710
uniprot id: F5Y6A2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

365046:RTA RS17455
gene id: 365046:RTA_RS17455
uniprot id: F5XZG8
names: Similarity
messages: Belongs to the DNA photolyase family.

365046:RTA RS10395
gene id: 365046:RTA_RS10395
uniprot id: F5XXY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

365046:RTA RS07410
gene id: 365046:RTA_RS07410
uniprot id: F5Y474
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

365046:RTA RS19025
gene id: 365046:RTA_RS19025
uniprot id: F5Y266
names: Similarity
messages: Belongs to the CFA/CMAS family.

365046:RTA RS16215
gene id: 365046:RTA_RS16215
uniprot id: F5XXE8
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

365046:RTA RS15850
gene id: 365046:RTA_RS15850
uniprot id: F5XWR5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

365046:RTA RS07230
gene id: 365046:RTA_RS07230
uniprot id: F5Y434
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

365046:RTA RS09415
gene id: 365046:RTA_RS09415
uniprot id: F5XWH3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
messages: Cytoplasm
messages: Homodimer. Forms a heterotetramer with IscU, interacts with other sulfur acceptors.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.

365046:RTA RS16980
gene id: 365046:RTA_RS16980
uniprot id: F5XYR7
names: Function
names: Similarity
messages: Belongs to the RapZ-like family.
messages: Displays ATPase and GTPase activities.

365046:RTA RS04050
gene id: 365046:RTA_RS04050
uniprot id: F5XY79
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MsrP family.
messages: Binds 1 Mo-molybdopterin (Mo-MPT) cofactor per subunit.
messages: Heterodimer of a catalytic subunit (MsrP) and a heme-binding subunit (MsrQ).
messages: Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide.
messages: Periplasm
messages: Predicted to be exported by the Tat system. The position of the signal peptide cleavage has not been experimentally proven.

365046:RTA RS15840
gene id: 365046:RTA_RS15840
uniprot id: F5XWR3
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

365046:RTA RS15485
gene id: 365046:RTA_RS15485
uniprot id: F5XW34
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

365046:RTA RS17305
gene id: 365046:RTA_RS17305
uniprot id: F5XZE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

365046:RTA RS07510
gene id: 365046:RTA_RS07510
uniprot id: F5Y493
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

365046:RTA RS14390
gene id: 365046:RTA_RS14390
uniprot id: F5Y573
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Cell inner membrane
messages: Membrane

365046:RTA RS11345
gene id: 365046:RTA_RS11345
uniprot id: F5XZV2
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

365046:RTA RS04010
gene id: 365046:RTA_RS04010
uniprot id: F5XY72
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

365046:RTA RS07015
gene id: 365046:RTA_RS07015
uniprot id: F5Y3I2
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
messages: O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.

365046:RTA RS09835
gene id: 365046:RTA_RS09835
uniprot id: F5XX65
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. RlmB subfamily.
messages: Cytoplasm
messages: Specifically methylates the ribose of guanosine 2251 in 23S rRNA.

365046:RTA RS01470
gene id: 365046:RTA_RS01470
uniprot id: F5Y4P6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

365046:RTA RS09305
gene id: 365046:RTA_RS09305
uniprot id: F5XWF1
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

365046:RTA RS18575
gene id: 365046:RTA_RS18575
uniprot id: F5Y1F9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

365046:RTA RS00385
gene id: 365046:RTA_RS00385
uniprot id: F5Y2G6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

365046:RTA RS18900
gene id: 365046:RTA_RS18900
uniprot id: F5Y241
names: Similarity
messages: Belongs to the DprA/Smf family.

365046:RTA RS10710
gene id: 365046:RTA_RS10710
uniprot id: F5XYL1
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

365046:RTA RS09350
gene id: 365046:RTA_RS09350
uniprot id: F5XWG0
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

365046:RTA RS10100
gene id: 365046:RTA_RS10100
uniprot id: F5XXS5
names: Similarity
messages: Belongs to the UPF0125 (RnfH) family.

365046:RTA RS01105
gene id: 365046:RTA_RS01105
uniprot id: F5Y411
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HPrK/P family.
messages: Both phosphorylation and phosphorolysis are carried out by the same active site and suggest a common mechanism for both reactions.
messages: Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr).
messages: Homohexamer.
messages: The Walker A ATP-binding motif also binds Pi and PPi.

365046:RTA RS14610
gene id: 365046:RTA_RS14610
uniprot id: F5Y5S3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

365046:RTA RS03065
gene id: 365046:RTA_RS03065
uniprot id: F5XWA8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

365046:RTA RS12380
gene id: 365046:RTA_RS12380
uniprot id: F5Y1B6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

365046:RTA RS01485
gene id: 365046:RTA_RS01485
uniprot id: F5Y4P9
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

365046:RTA RS04285
gene id: 365046:RTA_RS04285
uniprot id: F5XYC5
names: Similarity
messages: Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.

365046:RTA RS10895
gene id: 365046:RTA_RS10895
uniprot id: F5XZ53
names: Similarity
messages: Belongs to the MipA/OmpV family.

365046:RTA RS09965
gene id: 365046:RTA_RS09965
uniprot id: F5XX90
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

365046:RTA RS15610
gene id: 365046:RTA_RS15610
uniprot id: F5XWL7
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

365046:RTA RS09185
gene id: 365046:RTA_RS09185
uniprot id: F5XVW7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

365046:RTA RS00185
gene id: 365046:RTA_RS00185
uniprot id: F5Y2C4
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.

365046:RTA RS16905
gene id: 365046:RTA_RS16905
uniprot id: F5XYQ3
names: Similarity
messages: Belongs to the glycosyl hydrolase 8 (cellulase D) family.

365046:RTA RS14320
gene id: 365046:RTA_RS14320
uniprot id: F5Y559
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.

365046:RTA RS11220
gene id: 365046:RTA_RS11220
uniprot id: F5XZS7
names: Function
names: Similarity
messages: Belongs to the LpxK family.
messages: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

365046:RTA RS06165
gene id: 365046:RTA_RS06165
uniprot id: F5Y1N9
names: Similarity
messages: Belongs to the UPF0111 family.

365046:RTA RS03140
gene id: 365046:RTA_RS03140
uniprot id: F5XWC3
names: Subcellular Location Annotation
messages: Membrane

365046:RTA RS11040
gene id: 365046:RTA_RS11040
uniprot id: F5XZ82
names: Similarity
messages: Belongs to the DapA family.

365046:RTA RS16685
gene id: 365046:RTA_RS16685
uniprot id: F5XY53
names: Similarity
messages: Belongs to the peptidase M20 family.

365046:RTA RS12255
gene id: 365046:RTA_RS12255
uniprot id: F5Y191
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

365046:RTA RS10745
gene id: 365046:RTA_RS10745
uniprot id: F5XYL8
names: Similarity
messages: Belongs to the GSP E family.

365046:RTA RS11550
gene id: 365046:RTA_RS11550
uniprot id: F5XZZ1
names: Similarity
messages: Belongs to the phosphate/phosphite/phosphonate binding protein family.

365046:RTA RS11000
gene id: 365046:RTA_RS11000
uniprot id: F5XZ74
names: Similarity
messages: Belongs to the AHA1 family.

365046:RTA RS18105
gene id: 365046:RTA_RS18105
uniprot id: F5Y0R0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial secretin family. GSP D subfamily.
messages: Cell outer membrane

365046:RTA RS00955
gene id: 365046:RTA_RS00955
uniprot id: F5Y3Y1
names: Subcellular Location Annotation
messages: Membrane

365046:RTA RS17770
gene id: 365046:RTA_RS17770
uniprot id: F5Y038
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

365046:RTA RS01060
gene id: 365046:RTA_RS01060
uniprot id: F5Y402
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

365046:RTA RS17965
gene id: 365046:RTA_RS17965
uniprot id: F5Y077
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

365046:RTA RS14825
gene id: 365046:RTA_RS14825
uniprot id: F5Y6C5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family. QueF type 2 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm
messages: Homodimer.

365046:RTA RS18470
gene id: 365046:RTA_RS18470
uniprot id: F5Y1D8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

365046:RTA RS18930
gene id: 365046:RTA_RS18930
uniprot id: F5Y247
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.

365046:RTA RS18330
gene id: 365046:RTA_RS18330
uniprot id: F5Y0V1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

365046:RTA RS07955
gene id: 365046:RTA_RS07955
uniprot id: F5Y4Y8
names: Similarity
messages: Belongs to the HSP15 family.

365046:RTA RS02305
gene id: 365046:RTA_RS02305
uniprot id: F5Y623
names: Activity Regulation
names: Caution
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

365046:RTA RS05460
gene id: 365046:RTA_RS05460
uniprot id: F5Y0C9
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

365046:RTA RS07110
gene id: 365046:RTA_RS07110
uniprot id: F5Y3K1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

365046:RTA RS05800
gene id: 365046:RTA_RS05800
uniprot id: F5Y0Z9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Cu-Zn superoxide dismutase family.
messages: Binds 1 copper ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

365046:RTA RS05670
gene id: 365046:RTA_RS05670
uniprot id: F5Y0X3
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

365046:RTA RS18530
gene id: 365046:RTA_RS18530
uniprot id: F5Y1F0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

365046:RTA RS03610
gene id: 365046:RTA_RS03610
uniprot id: F5XXI2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HesB/IscA family.
messages: Binds 1 iron-sulfur cluster per subunit.
messages: Homodimer.
messages: Required for insertion of 4Fe-4S clusters.

365046:RTA RS04960
gene id: 365046:RTA_RS04960
uniprot id: F5XZM5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell inner membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

365046:RTA RS13470
gene id: 365046:RTA_RS13470
uniprot id: F5Y3S7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell inner membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

365046:RTA RS11080
gene id: 365046:RTA_RS11080
uniprot id: F5XZ90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

365046:RTA RS19145
gene id: 365046:RTA_RS19145
uniprot id: F5Y290
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 2 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

365046:RTA RS17795
gene id: 365046:RTA_RS17795
uniprot id: F5Y043
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

365046:RTA RS16995
gene id: 365046:RTA_RS16995
uniprot id: F5XYS0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

365046:RTA RS01030
gene id: 365046:RTA_RS01030
uniprot id: F5Y3Z6
names: Function
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

365046:RTA RS05190
gene id: 365046:RTA_RS05190
uniprot id: F5XZS1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

365046:RTA RS08470
gene id: 365046:RTA_RS08470
uniprot id: F5Y655
names: Similarity
messages: Belongs to the universal stress protein A family.

365046:RTA RS16390
gene id: 365046:RTA_RS16390
uniprot id: F5XXZ3
names: Similarity
messages: Belongs to the RecJ family.

365046:RTA RS18400
gene id: 365046:RTA_RS18400
uniprot id: F5Y1C6
names: Function
names: Similarity
messages: ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
messages: Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.

365046:RTA RS13710
gene id: 365046:RTA_RS13710
uniprot id: F5Y4D4
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

365046:RTA RS08905
gene id: 365046:RTA_RS08905
uniprot id: F5XVR4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
messages: Cytoplasm

365046:RTA RS14440
gene id: 365046:RTA_RS14440
uniprot id: F5Y5N9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

365046:RTA RS04275
gene id: 365046:RTA_RS04275
uniprot id: F5XYC3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatB family.
messages: Cell inner membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

365046:RTA RS16260
gene id: 365046:RTA_RS16260
uniprot id: F5XXF7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

365046:RTA RS11850
gene id: 365046:RTA_RS11850
uniprot id: F5Y0K6
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

365046:RTA RS16625
gene id: 365046:RTA_RS16625
uniprot id: F5XY41
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

365046:RTA RS01670
gene id: 365046:RTA_RS01670
uniprot id: F5Y594
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

365046:RTA RS17030
gene id: 365046:RTA_RS17030
uniprot id: F5XYS6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

365046:RTA RS08125
gene id: 365046:RTA_RS08125
uniprot id: F5Y5H7
names: Subcellular Location Annotation
messages: Membrane

365046:RTA RS18475
gene id: 365046:RTA_RS18475
uniprot id: F5Y1D9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

365046:RTA RS17010
gene id: 365046:RTA_RS17010
uniprot id: F5XYS3
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

365046:RTA RS11235
gene id: 365046:RTA_RS11235
uniprot id: F5XZT0
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

365046:RTA RS14255
gene id: 365046:RTA_RS14255
uniprot id: F5Y546
names: Similarity
messages: Belongs to the UPF0162 family.

365046:RTA RS18775
gene id: 365046:RTA_RS18775
uniprot id: F5Y216
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acetylates the N-terminal alanine of ribosomal protein S18.
messages: Belongs to the acetyltransferase family. RimI subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

365046:RTA RS07000
gene id: 365046:RTA_RS07000
uniprot id: F5Y3H9
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.
messages: Cytoplasm

365046:RTA RS10050
gene id: 365046:RTA_RS10050
uniprot id: F5XXR5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

365046:RTA RS14590
gene id: 365046:RTA_RS14590
uniprot id: F5Y5R9
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

365046:RTA RS17520
gene id: 365046:RTA_RS17520
uniprot id: F5XZI1
names: Similarity
messages: Belongs to the transcriptional regulatory Fis family.

365046:RTA RS16155
gene id: 365046:RTA_RS16155
uniprot id: F5XXD6
names: Subcellular Location Annotation
messages: Membrane

365046:RTA RS18500
gene id: 365046:RTA_RS18500
uniprot id: F5Y1E4
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

365046:RTA RS10425
gene id: 365046:RTA_RS10425
uniprot id: F5XYF2
names: Activity Regulation
names: Caution
names: Domain
names: Function
names: Similarity
messages: Belongs to the GlnD family.
messages: Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism.
messages: Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity.

365046:RTA RS00235
gene id: 365046:RTA_RS00235
uniprot id: F5Y2D4
names: Subcellular Location Annotation
messages: Membrane

365046:RTA RS14370
gene id: 365046:RTA_RS14370
uniprot id: F5Y569
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 2 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

365046:RTA RS07470
gene id: 365046:RTA_RS07470
uniprot id: F5Y485
names: Subcellular Location Annotation
messages: Membrane

365046:RTA RS17185
gene id: 365046:RTA_RS17185
uniprot id: F5XZB6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the selenophosphate synthase 1 family. Class I subfamily.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Homodimer.
messages: Synthesizes selenophosphate from selenide and ATP.

365046:RTA RS17245
gene id: 365046:RTA_RS17245
uniprot id: F5XZC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

365046:RTA RS19615
gene id: 365046:RTA_RS19615
uniprot id: F5XW67
names: Subcellular Location Annotation
messages: Membrane

365046:RTA RS05655
gene id: 365046:RTA_RS05655
uniprot id: F5Y0X0
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

365046:RTA RS01725
gene id: 365046:RTA_RS01725
uniprot id: F5Y5A5
names: Subcellular Location Annotation
messages: Cytoplasm

365046:RTA RS17255
gene id: 365046:RTA_RS17255
uniprot id: F5XZC9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COX11/CtaG family.
messages: Cell inner membrane
messages: Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I.

365046:RTA RS13980
gene id: 365046:RTA_RS13980
uniprot id: F5Y4I9
names: Subcellular Location Annotation
messages: Membrane

365046:RTA RS12050
gene id: 365046:RTA_RS12050
uniprot id: F5Y151
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PstS family.
messages: Part of the ABC transporter complex PstSACB involved in phosphate import.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

365046:RTA RS14860
gene id: 365046:RTA_RS14860
uniprot id: F5Y6D2
names: Similarity
messages: Belongs to the glutaredoxin family. Monothiol subfamily.

365046:RTA RS18540
gene id: 365046:RTA_RS18540
uniprot id: F5Y1F2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

365046:RTA RS09420
gene id: 365046:RTA_RS09420
uniprot id: F5XWH4
names: Function
names: Similarity
messages: A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.
messages: Belongs to the NifU family.

365046:RTA RS02525
gene id: 365046:RTA_RS02525
uniprot id: F5XVJ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

365046:RTA RS17680
gene id: 365046:RTA_RS17680
uniprot id: F5Y020
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

365046:RTA RS03260
gene id: 365046:RTA_RS03260
uniprot id: F5XWV5
names: Function
names: Similarity
messages: Belongs to the catalase family.
messages: Has an organic peroxide-dependent peroxidase activity.

365046:RTA RS10840
gene id: 365046:RTA_RS10840
uniprot id: F5XZ42
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

365046:RTA RS00710
gene id: 365046:RTA_RS00710
uniprot id: F5Y3C4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

365046:RTA RS01625
gene id: 365046:RTA_RS01625
uniprot id: F5Y585
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

365046:RTA RS03895
gene id: 365046:RTA_RS03895
uniprot id: F5XXN9
names: Subcellular Location Annotation
messages: Membrane

365046:RTA RS03800
gene id: 365046:RTA_RS03800
uniprot id: F5XXM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Cell inner membrane
messages: Membrane

365046:RTA RS09590
gene id: 365046:RTA_RS09590
uniprot id: F5XWK7
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

365046:RTA RS03395
gene id: 365046:RTA_RS03395
uniprot id: F5XWY0
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

365046:RTA RS08880
gene id: 365046:RTA_RS08880
uniprot id: F5XVR0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

365046:RTA RS17625
gene id: 365046:RTA_RS17625
uniprot id: F5Y009
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

365046:RTA RS11810
gene id: 365046:RTA_RS11810
uniprot id: F5Y0J8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-insensitive subfamily.
messages: Cell inner membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force.

365046:RTA RS06230
gene id: 365046:RTA_RS06230
uniprot id: F5Y1Q2
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

365046:RTA RS19195
gene id: 365046:RTA_RS19195
uniprot id: F5Y2Y8
names: Similarity
messages: Belongs to the type IA topoisomerase family.

365046:RTA RS18010
gene id: 365046:RTA_RS18010
uniprot id: F5Y0P1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

365046:RTA RS02005
gene id: 365046:RTA_RS02005
uniprot id: F5Y5W5
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.

365046:RTA RS12615
gene id: 365046:RTA_RS12615
uniprot id: F5Y1X8
names: Similarity
messages: Belongs to the histone deacetylase family.

365046:RTA RS07735
gene id: 365046:RTA_RS07735
uniprot id: F5Y4U5
names: Similarity
messages: Belongs to the pirin family.

365046:RTA RS01655
gene id: 365046:RTA_RS01655
uniprot id: F5Y591
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

365046:RTA RS19150
gene id: 365046:RTA_RS19150
uniprot id: F5Y291
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

365046:RTA RS17335
gene id: 365046:RTA_RS17335
uniprot id: F5XZE5
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

365046:RTA RS09645
gene id: 365046:RTA_RS09645
uniprot id: F5XX28
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

365046:RTA RS00165
gene id: 365046:RTA_RS00165
uniprot id: F5Y2C0
names: Function
names: Similarity
messages: Belongs to the MinE family.
messages: Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.

365046:RTA RS08300
gene id: 365046:RTA_RS08300
uniprot id: F5Y5L2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell inner membrane

365046:RTA RS11300
gene id: 365046:RTA_RS11300
uniprot id: F5XZU3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

365046:RTA RS07005
gene id: 365046:RTA_RS07005
uniprot id: F5Y3I0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

365046:RTA RS18480
gene id: 365046:RTA_RS18480
uniprot id: F5Y1E0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

365046:RTA RS14565
gene id: 365046:RTA_RS14565
uniprot id: F5Y5R4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Periplasm

365046:RTA RS10850
gene id: 365046:RTA_RS10850
uniprot id: F5XZ44
names: Similarity
messages: Belongs to the GARS family.

365046:RTA RS09725
gene id: 365046:RTA_RS09725
uniprot id: F5XX43
names: Similarity
messages: Belongs to the YfgM family.

365046:RTA RS06375
gene id: 365046:RTA_RS06375
uniprot id: F5Y1T1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

365046:RTA RS18890
gene id: 365046:RTA_RS18890
uniprot id: F5Y239
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

365046:RTA RS08270
gene id: 365046:RTA_RS08270
uniprot id: F5Y5K6
names: Similarity
messages: Belongs to the type IB topoisomerase family.

365046:RTA RS16250
gene id: 365046:RTA_RS16250
uniprot id: F5XXF5
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

365046:RTA RS01360
gene id: 365046:RTA_RS01360
uniprot id: F5Y4M2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

365046:RTA RS10265
gene id: 365046:RTA_RS10265
uniprot id: F5XXV8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

365046:RTA RS05170
gene id: 365046:RTA_RS05170
uniprot id: F5XZR7
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.

365046:RTA RS15525
gene id: 365046:RTA_RS15525
uniprot id: F5XW41
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

365046:RTA RS15730
gene id: 365046:RTA_RS15730
uniprot id: F5XWP1
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.

365046:RTA RS11145
gene id: 365046:RTA_RS11145
uniprot id: F5XZA3
names: Similarity
messages: Belongs to the class-A beta-lactamase family.

365046:RTA RS15425
gene id: 365046:RTA_RS15425
uniprot id: F5XW21
names: Subcellular Location Annotation
messages: Membrane

365046:RTA RS19210
gene id: 365046:RTA_RS19210
uniprot id: F5Y2Z1
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

365046:RTA RS14900
gene id: 365046:RTA_RS14900
uniprot id: F5Y6E0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

365046:RTA RS11880
gene id: 365046:RTA_RS11880
uniprot id: F5Y0L2
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

365046:RTA RS09440
gene id: 365046:RTA_RS09440
uniprot id: F5XWH8
names: Similarity
messages: Belongs to the adrenodoxin/putidaredoxin family.

365046:RTA RS10785
gene id: 365046:RTA_RS10785
uniprot id: F5XYM5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TolB family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: Periplasm
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

365046:RTA RS04255
gene id: 365046:RTA_RS04255
uniprot id: F5XYB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA-PH family.
messages: Cytoplasm

365046:RTA RS01110
gene id: 365046:RTA_RS01110
uniprot id: F5Y412
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Cytoplasm
messages: Homodimer.

365046:RTA RS04855
gene id: 365046:RTA_RS04855
uniprot id: F5XZK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

365046:RTA RS08370
gene id: 365046:RTA_RS08370
uniprot id: F5Y5M5
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

365046:RTA RS15665
gene id: 365046:RTA_RS15665
uniprot id: F5XWM8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.

365046:RTA RS07085
gene id: 365046:RTA_RS07085
uniprot id: F5Y3J6
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

365046:RTA RS06325
gene id: 365046:RTA_RS06325
uniprot id: F5Y1S1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

365046:RTA RS09310
gene id: 365046:RTA_RS09310
uniprot id: F5XWF2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

365046:RTA RS01010
gene id: 365046:RTA_RS01010
uniprot id: F5Y3Z2
names: Similarity
names: Subunit
messages: Belongs to the Nudix hydrolase family. NudJ subfamily.
messages: Monomer.

365046:RTA RS16415
gene id: 365046:RTA_RS16415
uniprot id: F5XXZ8
names: Subcellular Location Annotation
messages: Membrane

365046:RTA RS11895
gene id: 365046:RTA_RS11895
uniprot id: F5Y0L5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Monomer.
messages: Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.

365046:RTA RS09690
gene id: 365046:RTA_RS09690
uniprot id: F5XX36
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

365046:RTA RS21015
gene id: 365046:RTA_RS21015
uniprot id: F5Y4C4
names: Function
names: Similarity
messages: Belongs to the MqnA/MqnD family. MqnA subfamily.
messages: Catalyzes the dehydration of chorismate into 3-[(1-carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).

365046:RTA RS00580
gene id: 365046:RTA_RS00580
uniprot id: F5Y396
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

365046:RTA RS08920
gene id: 365046:RTA_RS08920
uniprot id: F5XVR6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

365046:RTA RS12355
gene id: 365046:RTA_RS12355
uniprot id: F5Y1B1
names: Subcellular Location Annotation
messages: Membrane

365046:RTA RS04765
gene id: 365046:RTA_RS04765
uniprot id: F5XZ27
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

365046:RTA RS07760
gene id: 365046:RTA_RS07760
uniprot id: F5Y4V0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

365046:RTA RS14530
gene id: 365046:RTA_RS14530
uniprot id: F5Y5Q7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

365046:RTA RS04525
gene id: 365046:RTA_RS04525
uniprot id: F5XYX7
names: Subcellular Location Annotation
messages: Membrane

365046:RTA RS09510
gene id: 365046:RTA_RS09510
uniprot id: F5XWJ2
names: Function
names: Subunit
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease.

365046:RTA RS00690
gene id: 365046:RTA_RS00690
uniprot id: F5Y3C0
names: Similarity
messages: Belongs to the P(II) protein family.

365046:RTA RS07715
gene id: 365046:RTA_RS07715
uniprot id: F5Y4U1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

365046:RTA RS08360
gene id: 365046:RTA_RS08360
uniprot id: F5Y5M3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

365046:RTA RS11270
gene id: 365046:RTA_RS11270
uniprot id: F5XZT7
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

365046:RTA RS17990
gene id: 365046:RTA_RS17990
uniprot id: F5Y0N7
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

365046:RTA RS09405
gene id: 365046:RTA_RS09405
uniprot id: F5XWH1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

365046:RTA RS06330
gene id: 365046:RTA_RS06330
uniprot id: F5Y1S2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

365046:RTA RS06710
gene id: 365046:RTA_RS06710
uniprot id: F5Y2N5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial solute-binding protein 7 family.
messages: Homodimer.
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: Periplasm

365046:RTA RS04645
gene id: 365046:RTA_RS04645
uniprot id: F5XZ04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

365046:RTA RS04035
gene id: 365046:RTA_RS04035
uniprot id: F5XY76
names: PTM
messages: Binds 2 heme c groups covalently per subunit.

365046:RTA RS07905
gene id: 365046:RTA_RS07905
uniprot id: F5Y4X9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

365046:RTA RS10495
gene id: 365046:RTA_RS10495
uniprot id: F5XYG6
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

365046:RTA RS14220
gene id: 365046:RTA_RS14220
uniprot id: F5Y539
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase C chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

365046:RTA RS14600
gene id: 365046:RTA_RS14600
uniprot id: F5Y5S1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

365046:RTA RS17510
gene id: 365046:RTA_RS17510
uniprot id: F5XZH9
names: Similarity
messages: Belongs to the asparagine synthetase family.

365046:RTA RS16795
gene id: 365046:RTA_RS16795
uniprot id: F5XYN2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UreE family.
messages: Cytoplasm
messages: Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly.

365046:RTA RS12805
gene id: 365046:RTA_RS12805
uniprot id: F5Y2Q4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

365046:RTA RS01785
gene id: 365046:RTA_RS01785
uniprot id: F5Y5B7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase C chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

365046:RTA RS14715
gene id: 365046:RTA_RS14715
uniprot id: F5Y5U3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

365046:RTA RS02595
gene id: 365046:RTA_RS02595
uniprot id: F5XVL3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

365046:RTA RS11105
gene id: 365046:RTA_RS11105
uniprot id: F5XZ95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

365046:RTA RS02395
gene id: 365046:RTA_RS02395
uniprot id: F5XVH3
names: Similarity
messages: Belongs to the GSP E family.

365046:RTA RS05380
gene id: 365046:RTA_RS05380
uniprot id: F5Y0B4
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

365046:RTA RS01930
gene id: 365046:RTA_RS01930
uniprot id: F5Y5E5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

365046:RTA RS11925
gene id: 365046:RTA_RS11925
uniprot id: F5Y0M1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

365046:RTA RS14280
gene id: 365046:RTA_RS14280
uniprot id: F5Y551
names: Caution
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

365046:RTA RS14405
gene id: 365046:RTA_RS14405
uniprot id: F5Y576
names: Similarity
messages: Belongs to the citrate synthase family.

365046:RTA RS08850
gene id: 365046:RTA_RS08850
uniprot id: F5XVQ4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

365046:RTA RS16220
gene id: 365046:RTA_RS16220
uniprot id: F5XXE9
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

365046:RTA RS06695
gene id: 365046:RTA_RS06695
uniprot id: F5Y2N2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

365046:RTA RS17235
gene id: 365046:RTA_RS17235
uniprot id: F5XZC5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF1 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

365046:RTA RS07145
gene id: 365046:RTA_RS07145
uniprot id: F5Y3K8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

365046:RTA RS14040
gene id: 365046:RTA_RS14040
uniprot id: F5Y507
names: Subcellular Location Annotation
messages: Membrane

365046:RTA RS17550
gene id: 365046:RTA_RS17550
uniprot id: F5XZI7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbC subfamily.
messages: Periplasm
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process.

365046:RTA RS17790
gene id: 365046:RTA_RS17790
uniprot id: F5Y042
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

365046:RTA RS02000
gene id: 365046:RTA_RS02000
uniprot id: F5Y5W4
names: Function
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. S-2-haloalkanoic acid dehalogenase family.
messages: Catalyzes the hydrolytic dehalogenation of small (S)-2-haloalkanoic acids to yield the corresponding (R)-2-hydroxyalkanoic acids.

365046:RTA RS04465
gene id: 365046:RTA_RS04465
uniprot id: F5XYW5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

365046:RTA RS06385
gene id: 365046:RTA_RS06385
uniprot id: F5Y1T3
names: Similarity
messages: Belongs to the PrpF family.

365046:RTA RS16585
gene id: 365046:RTA_RS16585
uniprot id: F5XY33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

365046:RTA RS17945
gene id: 365046:RTA_RS17945
uniprot id: F5Y073
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.

365046:RTA RS19425
gene id: 365046:RTA_RS19425
uniprot id: F5Y334
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

365046:RTA RS18980
gene id: 365046:RTA_RS18980
uniprot id: F5Y257
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

365046:RTA RS13635
gene id: 365046:RTA_RS13635
uniprot id: F5Y4B9
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

365046:RTA RS08045
gene id: 365046:RTA_RS08045
uniprot id: F5Y5G5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

365046:RTA RS18915
gene id: 365046:RTA_RS18915
uniprot id: F5Y244
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

365046:RTA RS02400
gene id: 365046:RTA_RS02400
uniprot id: F5XVH4
names: Similarity
messages: Belongs to the GSP E family.

365046:RTA RS02885
gene id: 365046:RTA_RS02885
uniprot id: F5XW72
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

365046:RTA RS03145
gene id: 365046:RTA_RS03145
uniprot id: F5XWC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

365046:RTA RS18205
gene id: 365046:RTA_RS18205
uniprot id: F5Y0T0
names: Subcellular Location Annotation
messages: Membrane

365046:RTA RS04455
gene id: 365046:RTA_RS04455
uniprot id: F5XYW3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

365046:RTA RS09325
gene id: 365046:RTA_RS09325
uniprot id: F5XWF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

365046:RTA RS18075
gene id: 365046:RTA_RS18075
uniprot id: F5Y0Q4
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GSP I family.
messages: Cell inner membrane
messages: Cleaved by prepilin peptidase.
messages: Component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.
messages: Membrane
messages: Type II secretion is composed of four main components: the outer membrane complex, the inner membrane complex, the cytoplasmic secretion ATPase and the periplasm-spanning pseudopilus.

365046:RTA RS08755
gene id: 365046:RTA_RS08755
uniprot id: F5Y6B1
names: Similarity
messages: Belongs to the thioredoxin family.

365046:RTA RS15830
gene id: 365046:RTA_RS15830
uniprot id: F5XWR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

365046:RTA RS14525
gene id: 365046:RTA_RS14525
uniprot id: F5Y5Q6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

365046:RTA RS01140
gene id: 365046:RTA_RS01140
uniprot id: F5Y418
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LptE lipoprotein family.
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptD.
messages: Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane.

365046:RTA RS17025
gene id: 365046:RTA_RS17025
uniprot id: F5XYS5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

365046:RTA RS14685
gene id: 365046:RTA_RS14685
uniprot id: F5Y5T8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PEPCase type 1 family.
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
messages: Homotetramer.

365046:RTA RS11455
gene id: 365046:RTA_RS11455
uniprot id: F5XZX2
names: Subcellular Location Annotation
messages: Membrane

365046:RTA RS08810
gene id: 365046:RTA_RS08810
uniprot id: F5Y6C2
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

365046:RTA RS04770
gene id: 365046:RTA_RS04770
uniprot id: F5XZ28
names: Subcellular Location Annotation
messages: Membrane

365046:RTA RS11570
gene id: 365046:RTA_RS11570
uniprot id: F5XZZ5
names: Function
names: Similarity
messages: Belongs to the Fe(2+)-trafficking protein family.
messages: Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.

365046:RTA RS10045
gene id: 365046:RTA_RS10045
uniprot id: F5XXR4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

365046:RTA RS08025
gene id: 365046:RTA_RS08025
uniprot id: F5Y5G1
names: Subcellular Location Annotation
messages: Membrane

365046:RTA RS14940
gene id: 365046:RTA_RS14940
uniprot id: F5Y6E7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ZapD family.
messages: Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity.
messages: Cytoplasm
messages: Interacts with FtsZ.

365046:RTA RS19540
gene id: 365046:RTA_RS19540
uniprot id: F5Y357
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell inner membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

365046:RTA RS11135
gene id: 365046:RTA_RS11135
uniprot id: F5XZA1
names: Similarity
messages: Belongs to the GST superfamily. Zeta family.

365046:RTA RS08835
gene id: 365046:RTA_RS08835
uniprot id: F5XVQ1
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

365046:RTA RS12890
gene id: 365046:RTA_RS12890
uniprot id: F5Y2S1
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

365046:RTA RS07515
gene id: 365046:RTA_RS07515
uniprot id: F5Y494
names: Similarity
messages: Belongs to the GcvT family.

365046:RTA RS07395
gene id: 365046:RTA_RS07395
uniprot id: F5Y471
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes.

365046:RTA RS06275
gene id: 365046:RTA_RS06275
uniprot id: F5Y1R1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

365046:RTA RS04975
gene id: 365046:RTA_RS04975
uniprot id: F5XZM8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsQ/DivIB family. FtsQ subfamily.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly.
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

365046:RTA RS07895
gene id: 365046:RTA_RS07895
uniprot id: F5Y4X7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

365046:RTA RS12350
gene id: 365046:RTA_RS12350
uniprot id: F5Y1B0
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

365046:RTA RS07725
gene id: 365046:RTA_RS07725
uniprot id: F5Y4U3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

365046:RTA RS12825
gene id: 365046:RTA_RS12825
uniprot id: F5Y2Q8
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

365046:RTA RS10555
gene id: 365046:RTA_RS10555
uniprot id: F5XYH8
names: Cofactor
names: Similarity
messages: Belongs to the UPF0313 family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

365046:RTA RS15360
gene id: 365046:RTA_RS15360
uniprot id: F5XW05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

365046:RTA RS16530
gene id: 365046:RTA_RS16530
uniprot id: F5XY22
names: Subcellular Location Annotation
messages: Membrane

365046:RTA RS18240
gene id: 365046:RTA_RS18240
uniprot id: F5Y0T7
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

365046:RTA RS02520
gene id: 365046:RTA_RS02520
uniprot id: F5XVJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

365046:RTA RS00505
gene id: 365046:RTA_RS00505
uniprot id: F5Y378
names: Function
names: Similarity
messages: Belongs to the esterase D family.
messages: Serine hydrolase involved in the detoxification of formaldehyde.

365046:RTA RS17515
gene id: 365046:RTA_RS17515
uniprot id: F5XZI0
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

365046:RTA RS17100
gene id: 365046:RTA_RS17100
uniprot id: F5XYU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

365046:RTA RS07290
gene id: 365046:RTA_RS07290
uniprot id: F5Y446
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

365046:RTA RS10910
gene id: 365046:RTA_RS10910
uniprot id: F5XZ56
names: Subcellular Location Annotation
messages: Membrane

365046:RTA RS09640
gene id: 365046:RTA_RS09640
uniprot id: F5XX27
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

365046:RTA RS14010
gene id: 365046:RTA_RS14010
uniprot id: F5Y501
names: Similarity
messages: Belongs to the class-A beta-lactamase family.

365046:RTA RS11760
gene id: 365046:RTA_RS11760
uniprot id: F5Y0I8
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

365046:RTA RS12935
gene id: 365046:RTA_RS12935
uniprot id: F5Y2S9
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

365046:RTA RS04655
gene id: 365046:RTA_RS04655
uniprot id: F5XZ06
names: Subcellular Location Annotation
messages: Membrane

365046:RTA RS06220
gene id: 365046:RTA_RS06220
uniprot id: F5Y1Q0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

365046:RTA RS09470
gene id: 365046:RTA_RS09470
uniprot id: F5XWI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

365046:RTA RS08515
gene id: 365046:RTA_RS08515
uniprot id: F5Y664
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

365046:RTA RS16790
gene id: 365046:RTA_RS16790
uniprot id: F5XYN1
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
messages: Binds 2 nickel ions per subunit.
messages: Carbamylation allows a single lysine to coordinate two nickel ions.
messages: Carboxylation allows a single lysine to coordinate two nickel ions.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

365046:RTA RS03890
gene id: 365046:RTA_RS03890
uniprot id: F5XXN8
names: Subcellular Location Annotation
messages: Membrane

365046:RTA RS05420
gene id: 365046:RTA_RS05420
uniprot id: F5Y0C1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

365046:RTA RS11545
gene id: 365046:RTA_RS11545
uniprot id: F5XZZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

365046:RTA RS11750
gene id: 365046:RTA_RS11750
uniprot id: F5Y0I6
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

365046:RTA RS06990
gene id: 365046:RTA_RS06990
uniprot id: F5Y3H7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

365046:RTA RS05680
gene id: 365046:RTA_RS05680
uniprot id: F5Y0X5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

365046:RTA RS07165
gene id: 365046:RTA_RS07165
uniprot id: F5Y3L2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

365046:RTA RS13305
gene id: 365046:RTA_RS13305
uniprot id: F5Y3P4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

365046:RTA RS07925
gene id: 365046:RTA_RS07925
uniprot id: F5Y4Y2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

365046:RTA RS01610
gene id: 365046:RTA_RS01610
uniprot id: F5Y582
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

365046:RTA RS10715
gene id: 365046:RTA_RS10715
uniprot id: F5XYL2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZipA family.
messages: Cell inner membrane
messages: Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins.

365046:RTA RS19815
gene id: 365046:RTA_RS19815
uniprot id: F5Y0M8
names: Caution
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

365046:RTA RS08925
gene id: 365046:RTA_RS08925
uniprot id: F5XVR7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

365046:RTA RS03255
gene id: 365046:RTA_RS03255
uniprot id: F5XWV4
names: Subcellular Location Annotation
messages: Periplasm

365046:RTA RS10355
gene id: 365046:RTA_RS10355
uniprot id: F5XXX7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YciB family.
messages: Cell inner membrane
messages: Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.

365046:RTA RS07865
gene id: 365046:RTA_RS07865
uniprot id: F5Y4X1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxH family.
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.
messages: Binds 2 Mn(2+) ions per subunit in a binuclear metal center.
messages: Cell inner membrane
messages: Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

365046:RTA RS17465
gene id: 365046:RTA_RS17465
uniprot id: F5XZH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

365046:RTA RS06455
gene id: 365046:RTA_RS06455
uniprot id: F5Y2I8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP G family.
messages: Cell inner membrane
messages: Membrane

365046:RTA RS18260
gene id: 365046:RTA_RS18260
uniprot id: F5Y0U1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

365046:RTA RS17090
gene id: 365046:RTA_RS17090
uniprot id: F5XYT8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

365046:RTA RS03905
gene id: 365046:RTA_RS03905
uniprot id: F5XXP1
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

365046:RTA RS15195
gene id: 365046:RTA_RS15195
uniprot id: F5Y6J8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliP/MopC/SpaP family.
messages: Cell membrane
messages: Membrane

365046:RTA RS15740
gene id: 365046:RTA_RS15740
uniprot id: F5XWP3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Homodimer.

365046:RTA RS14430
gene id: 365046:RTA_RS14430
uniprot id: F5Y5N7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

365046:RTA RS17875
gene id: 365046:RTA_RS17875
uniprot id: F5Y059
names: Subcellular Location Annotation
messages: Membrane

365046:RTA RS12885
gene id: 365046:RTA_RS12885
uniprot id: F5Y2S0
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

365046:RTA RS16000
gene id: 365046:RTA_RS16000
uniprot id: F5XXA4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Part of the binding-protein-dependent transport system for sn-glycerol-3-phosphate; probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (UgpC), two transmembrane proteins (UgpA and UgpE) and a solute-binding protein (UgpB).

365046:RTA RS17490
gene id: 365046:RTA_RS17490
uniprot id: F5XZH5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

365046:RTA RS02995
gene id: 365046:RTA_RS02995
uniprot id: F5XW94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

365046:RTA RS13505
gene id: 365046:RTA_RS13505
uniprot id: F5Y3T4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

365046:RTA RS04915
gene id: 365046:RTA_RS04915
uniprot id: F5XZL6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

365046:RTA RS12340
gene id: 365046:RTA_RS12340
uniprot id: F5Y1A8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

365046:RTA RS05620
gene id: 365046:RTA_RS05620
uniprot id: F5Y0W3
names: Similarity
messages: Belongs to the phosphohexose mutase family.

365046:RTA RS08410
gene id: 365046:RTA_RS08410
uniprot id: F5Y643
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

365046:RTA RS19315
gene id: 365046:RTA_RS19315
uniprot id: F5Y312
names: Similarity
messages: Belongs to the transketolase family.

365046:RTA RS18380
gene id: 365046:RTA_RS18380
uniprot id: F5Y1C2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

365046:RTA RS08295
gene id: 365046:RTA_RS08295
uniprot id: F5Y5L1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

365046:RTA RS18340
gene id: 365046:RTA_RS18340
uniprot id: F5Y0V3
names: Similarity
names: Subunit
messages: Belongs to the threonine aldolase family.
messages: Homotetramer.

365046:RTA RS02950
gene id: 365046:RTA_RS02950
uniprot id: F5XW85
names: Similarity
messages: Belongs to the peptidase S14 family.

365046:RTA RS03055
gene id: 365046:RTA_RS03055
uniprot id: F5XWA6
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

365046:RTA RS00745
gene id: 365046:RTA_RS00745
uniprot id: F5Y3D1
names: Similarity
messages: Belongs to the YciI family.

365046:RTA RS14540
gene id: 365046:RTA_RS14540
uniprot id: F5Y5Q9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell inner membrane
messages: Cytoplasm
messages: Monomer.

365046:RTA RS08455
gene id: 365046:RTA_RS08455
uniprot id: F5Y652
names: Function
names: Similarity
messages: Belongs to the CobT family.
messages: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).

365046:RTA RS13615
gene id: 365046:RTA_RS13615
uniprot id: F5Y4B5
names: Subcellular Location Annotation
messages: Membrane

365046:RTA RS13180
gene id: 365046:RTA_RS13180
uniprot id: F5Y2Y0
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

365046:RTA RS12115
gene id: 365046:RTA_RS12115
uniprot id: F5Y164
names: Cofactor
messages: Can also use Mn(2+) ion.

365046:RTA RS05470
gene id: 365046:RTA_RS05470
uniprot id: F5Y0D1
names: Subcellular Location Annotation
messages: Membrane

365046:RTA RS14510
gene id: 365046:RTA_RS14510
uniprot id: F5Y5Q3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

365046:RTA RS03635
gene id: 365046:RTA_RS03635
uniprot id: F5XXI7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

365046:RTA RS14245
gene id: 365046:RTA_RS14245
uniprot id: F5Y544
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

365046:RTA RS12960
gene id: 365046:RTA_RS12960
uniprot id: F5Y2T4
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

365046:RTA RS12860
gene id: 365046:RTA_RS12860
uniprot id: F5Y2R5
names: Similarity
messages: Belongs to the GbsR family.

365046:RTA RS08315
gene id: 365046:RTA_RS08315
uniprot id: F5Y5L5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

365046:RTA RS07875
gene id: 365046:RTA_RS07875
uniprot id: F5Y4X3
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

365046:RTA RS16090
gene id: 365046:RTA_RS16090
uniprot id: F5XXC3
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

365046:RTA RS11825
gene id: 365046:RTA_RS11825
uniprot id: F5Y0K1
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

365046:RTA RS13735
gene id: 365046:RTA_RS13735
uniprot id: F5Y4D9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
messages: Cell inner membrane
messages: Membrane
messages: Transport of potassium into the cell.

365046:RTA RS07465
gene id: 365046:RTA_RS07465
uniprot id: F5Y484
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

365046:RTA RS07945
gene id: 365046:RTA_RS07945
uniprot id: F5Y4Y6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

365046:RTA RS03945
gene id: 365046:RTA_RS03945
uniprot id: F5XXP9
names: Similarity
messages: Belongs to the carotenoid/retinoid oxidoreductase family.

365046:RTA RS02145
gene id: 365046:RTA_RS02145
uniprot id: F5Y5Z1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

365046:RTA RS08130
gene id: 365046:RTA_RS08130
uniprot id: F5Y5H8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I fumarase family.
messages: Catalyzes the reversible hydration of fumarate to (S)-malate.
messages: Homodimer.

365046:RTA RS17345
gene id: 365046:RTA_RS17345
uniprot id: F5XZE7
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.

365046:RTA RS06290
gene id: 365046:RTA_RS06290
uniprot id: F5Y1R4
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

365046:RTA RS11050
gene id: 365046:RTA_RS11050
uniprot id: F5XZ84
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

365046:RTA RS13485
gene id: 365046:RTA_RS13485
uniprot id: F5Y3T0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

365046:RTA RS03950
gene id: 365046:RTA_RS03950
uniprot id: F5XXQ0
names: Similarity
messages: Belongs to the lycopene cyclase family.

365046:RTA RS14260
gene id: 365046:RTA_RS14260
uniprot id: F5Y547
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell inner membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

365046:RTA RS06830
gene id: 365046:RTA_RS06830
uniprot id: F5Y3E6
names: Similarity
messages: Belongs to the ModE family.

365046:RTA RS17450
gene id: 365046:RTA_RS17450
uniprot id: F5XZG7
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

365046:RTA RS12645
gene id: 365046:RTA_RS12645
uniprot id: F5Y1Y4
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

365046:RTA RS01345
gene id: 365046:RTA_RS01345
uniprot id: F5Y4L9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

365046:RTA RS02830
gene id: 365046:RTA_RS02830
uniprot id: F5XW61
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell inner membrane
messages: Membrane

365046:RTA RS07780
gene id: 365046:RTA_RS07780
uniprot id: F5Y4V4
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

365046:RTA RS04030
gene id: 365046:RTA_RS04030
uniprot id: F5XY75
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

365046:RTA RS04965
gene id: 365046:RTA_RS04965
uniprot id: F5XZM6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

365046:RTA RS11460
gene id: 365046:RTA_RS11460
uniprot id: F5XZX3
names: Subcellular Location Annotation
messages: Membrane

365046:RTA RS18460
gene id: 365046:RTA_RS18460
uniprot id: F5Y1D6
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.