365044:PNAP RS12330
gene id: 365044:PNAP_RS12330
uniprot id: A1VQ43
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

365044:PNAP RS06905
gene id: 365044:PNAP_RS06905
uniprot id: A1VM16
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

365044:PNAP RS09875
gene id: 365044:PNAP_RS09875
uniprot id: A1VNQ1
names: Similarity
messages: Belongs to the HupF/HypC family.

365044:PNAP RS07135
gene id: 365044:PNAP_RS07135
uniprot id: A1VM65
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

365044:PNAP RS09870
gene id: 365044:PNAP_RS09870
uniprot id: A1VNQ0
names: Similarity
messages: Belongs to the HupG/HyaE family.

365044:PNAP RS00390
gene id: 365044:PNAP_RS00390
uniprot id: A1VIC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

365044:PNAP RS01020
gene id: 365044:PNAP_RS01020
uniprot id: A1VIQ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity).

365044:PNAP RS16780
gene id: 365044:PNAP_RS16780
uniprot id: A1VSM9
names: Function
names: Similarity
messages: Belongs to the Dus family. DusB subfamily.
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

365044:PNAP RS17085
gene id: 365044:PNAP_RS17085
uniprot id: A1VSU1
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

365044:PNAP RS04855
gene id: 365044:PNAP_RS04855
uniprot id: A1VKW1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UreF family.
messages: Cytoplasm
messages: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
messages: UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

365044:PNAP RS14450
gene id: 365044:PNAP_RS14450
uniprot id: A1VRB4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

365044:PNAP RS01685
gene id: 365044:PNAP_RS01685
uniprot id: A1VJ37
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

365044:PNAP RS11720
gene id: 365044:PNAP_RS11720
uniprot id: A1VPS2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NifD/NifK/NifE/NifN family.
messages: Binds 1 [8Fe-7S] cluster per heterodimer.
messages: Tetramer of two alpha and two beta chains. Forms complex with the iron protein (nitrogenase component 2).
messages: This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation.

365044:PNAP RS20885
gene id: 365044:PNAP_RS20885
uniprot id: A1VV00
names: Similarity
messages: Belongs to the GSP E family.

365044:PNAP RS07155
gene id: 365044:PNAP_RS07155
uniprot id: A1VM69
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

365044:PNAP RS13630
gene id: 365044:PNAP_RS13630
uniprot id: A1VQV3
names: Subcellular Location Annotation
messages: Membrane

365044:PNAP RS02450
gene id: 365044:PNAP_RS02450
uniprot id: A1VJI6
names: Similarity
messages: Belongs to the GbsR family.

365044:PNAP RS00815
gene id: 365044:PNAP_RS00815
uniprot id: A1VIL4
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

365044:PNAP RS03965
gene id: 365044:PNAP_RS03965
uniprot id: A1VKD9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

365044:PNAP RS06130
gene id: 365044:PNAP_RS06130
uniprot id: A1VLL1
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

365044:PNAP RS18540
gene id: 365044:PNAP_RS18540
uniprot id: A1VTM6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptA family.
messages: Component of the lipopolysaccharide transport and assembly complex.
messages: Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane.
messages: Periplasm

365044:PNAP RS18195
gene id: 365044:PNAP_RS18195
uniprot id: A1VTG2
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

365044:PNAP RS08870
gene id: 365044:PNAP_RS08870
uniprot id: A1VN54
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

365044:PNAP RS07220
gene id: 365044:PNAP_RS07220
uniprot id: A1VM82
names: Subcellular Location Annotation
messages: Membrane

365044:PNAP RS11100
gene id: 365044:PNAP_RS11100
uniprot id: A1VPE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

365044:PNAP RS15855
gene id: 365044:PNAP_RS15855
uniprot id: A1VS42
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

365044:PNAP RS01985
gene id: 365044:PNAP_RS01985
uniprot id: A1VJ98
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

365044:PNAP RS07455
gene id: 365044:PNAP_RS07455
uniprot id: A1VMC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

365044:PNAP RS05560
gene id: 365044:PNAP_RS05560
uniprot id: A1VL99
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Cell inner membrane
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.

365044:PNAP RS24440
gene id: 365044:PNAP_RS24440
uniprot id: A1VX08
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

365044:PNAP RS14630
gene id: 365044:PNAP_RS14630
uniprot id: A1VRF2
names: Similarity
messages: Belongs to the pirin family.

365044:PNAP RS07790
gene id: 365044:PNAP_RS07790
uniprot id: A1VMJ6
names: Caution
names: Function
names: Similarity
messages: Belongs to the bacterial two-domain DSD family.
messages: Catalyzes the conversion of 3-dehydroshikimate to protocatechuate (3,4-dihydroxybenzoate), a common intermediate of quinate and shikimate degradation pathways.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

365044:PNAP RS14775
gene id: 365044:PNAP_RS14775
uniprot id: A1VRH6
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

365044:PNAP RS08815
gene id: 365044:PNAP_RS08815
uniprot id: A1VN43
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

365044:PNAP RS07620
gene id: 365044:PNAP_RS07620
uniprot id: A1VMG2
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

365044:PNAP RS13865
gene id: 365044:PNAP_RS13865
uniprot id: A1VR00
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

365044:PNAP RS18680
gene id: 365044:PNAP_RS18680
uniprot id: A1VTQ4
names: Similarity
messages: Belongs to the prokaryotic GSH synthase family.

365044:PNAP RS15390
gene id: 365044:PNAP_RS15390
uniprot id: A1VRU8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

365044:PNAP RS08825
gene id: 365044:PNAP_RS08825
uniprot id: A1VN45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

365044:PNAP RS10625
gene id: 365044:PNAP_RS10625
uniprot id: A1VP49
names: Similarity
names: Subunit
messages: Belongs to the muconolactone Delta-isomerase family.
messages: Homodecamer.

365044:PNAP RS14395
gene id: 365044:PNAP_RS14395
uniprot id: A1VRA4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I fumarase family.
messages: Catalyzes the reversible hydration of fumarate to (S)-malate.
messages: Homodimer.

365044:PNAP RS01005
gene id: 365044:PNAP_RS01005
uniprot id: A1VIQ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

365044:PNAP RS19395
gene id: 365044:PNAP_RS19395
uniprot id: A1VU48
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

365044:PNAP RS17035
gene id: 365044:PNAP_RS17035
uniprot id: A1VST1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

365044:PNAP RS04305
gene id: 365044:PNAP_RS04305
uniprot id: A1VKK5
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

365044:PNAP RS07350
gene id: 365044:PNAP_RS07350
uniprot id: A1VMA8
names: Function
names: Similarity
messages: Belongs to the IMPDH/GMPR family. GuaC type 2 subfamily.
messages: Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.

365044:PNAP RS05375
gene id: 365044:PNAP_RS05375
uniprot id: A1VL67
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably interacts with PlsX.

365044:PNAP RS20425
gene id: 365044:PNAP_RS20425
uniprot id: A1VUR0
names: Similarity
messages: Belongs to the hyi family.

365044:PNAP RS04410
gene id: 365044:PNAP_RS04410
uniprot id: A1VKM6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell inner membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.

365044:PNAP RS14390
gene id: 365044:PNAP_RS14390
uniprot id: A1VRA3
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

365044:PNAP RS20830
gene id: 365044:PNAP_RS20830
uniprot id: A1VUY9
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

365044:PNAP RS02900
gene id: 365044:PNAP_RS02900
uniprot id: A1VJS6
names: Similarity
messages: Belongs to the thioredoxin family. DsbE subfamily.

365044:PNAP RS14005
gene id: 365044:PNAP_RS14005
uniprot id: A1VR28
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

365044:PNAP RS08435
gene id: 365044:PNAP_RS08435
uniprot id: A1VMX3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: Monomer.
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

365044:PNAP RS15050
gene id: 365044:PNAP_RS15050
uniprot id: A1VRN0
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

365044:PNAP RS15930
gene id: 365044:PNAP_RS15930
uniprot id: A1VS62
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 2 family.

365044:PNAP RS19120
gene id: 365044:PNAP_RS19120
uniprot id: A1VTZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

365044:PNAP RS09170
gene id: 365044:PNAP_RS09170
uniprot id: A1VNB4
names: Similarity
messages: Belongs to the BolA/IbaG family.

365044:PNAP RS05320
gene id: 365044:PNAP_RS05320
uniprot id: A1VL56
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.

365044:PNAP RS03360
gene id: 365044:PNAP_RS03360
uniprot id: A1VK20
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

365044:PNAP RS08880
gene id: 365044:PNAP_RS08880
uniprot id: A1VN56
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

365044:PNAP RS12295
gene id: 365044:PNAP_RS12295
uniprot id: A1VQ36
names: Subcellular Location Annotation
messages: Membrane

365044:PNAP RS14680
gene id: 365044:PNAP_RS14680
uniprot id: A1VRG2
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

365044:PNAP RS13405
gene id: 365044:PNAP_RS13405
uniprot id: A1VQQ8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

365044:PNAP RS07645
gene id: 365044:PNAP_RS07645
uniprot id: A1VMG7
names: Subcellular Location Annotation
messages: Membrane

365044:PNAP RS25335
gene id: 365044:PNAP_RS25335
uniprot id: A1VWT5
names: Similarity
messages: Belongs to the ParB family.

365044:PNAP RS07380
gene id: 365044:PNAP_RS07380
uniprot id: A1VMB4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

365044:PNAP RS17530
gene id: 365044:PNAP_RS17530
uniprot id: A1VT30
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

365044:PNAP RS15940
gene id: 365044:PNAP_RS15940
uniprot id: A1VS64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the etk/wzc family.
messages: Cell inner membrane
messages: Membrane

365044:PNAP RS00635
gene id: 365044:PNAP_RS00635
uniprot id: A1VIH5
names: Similarity
messages: Belongs to the glutathione peroxidase family.

365044:PNAP RS05805
gene id: 365044:PNAP_RS05805
uniprot id: A1VLE7
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

365044:PNAP RS13325
gene id: 365044:PNAP_RS13325
uniprot id: A1VQP1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

365044:PNAP RS20810
gene id: 365044:PNAP_RS20810
uniprot id: A1VUY5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

365044:PNAP RS22605
gene id: 365044:PNAP_RS22605
uniprot id: A1VVZ6
names: Subcellular Location Annotation
messages: Periplasm

365044:PNAP RS01640
gene id: 365044:PNAP_RS01640
uniprot id: A1VJ27
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

365044:PNAP RS08800
gene id: 365044:PNAP_RS08800
uniprot id: A1VN40
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

365044:PNAP RS01595
gene id: 365044:PNAP_RS01595
uniprot id: A1VJ19
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

365044:PNAP RS13155
gene id: 365044:PNAP_RS13155
uniprot id: A1VQK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

365044:PNAP RS14285
gene id: 365044:PNAP_RS14285
uniprot id: A1VR82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

365044:PNAP RS12175
gene id: 365044:PNAP_RS12175
uniprot id: A1VQ12
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the ferredoxin--NADP reductase type 2 family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

365044:PNAP RS11685
gene id: 365044:PNAP_RS11685
uniprot id: A1VPR5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

365044:PNAP RS15395
gene id: 365044:PNAP_RS15395
uniprot id: A1VRU9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

365044:PNAP RS17030
gene id: 365044:PNAP_RS17030
uniprot id: A1VST0
names: Function
names: Similarity
messages: Belongs to the LpxC family.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

365044:PNAP RS02445
gene id: 365044:PNAP_RS02445
uniprot id: A1VJI5
names: Function
names: Similarity
messages: Belongs to the RlpA family.
messages: Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.

365044:PNAP RS10510
gene id: 365044:PNAP_RS10510
uniprot id: A1VP25
names: Cofactor
messages: Binds 3 heme c groups covalently per subunit.

365044:PNAP RS22630
gene id: 365044:PNAP_RS22630
uniprot id: A1VW01
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Member of a two-component regulatory system.

365044:PNAP RS03475
gene id: 365044:PNAP_RS03475
uniprot id: A1VK43
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

365044:PNAP RS08110
gene id: 365044:PNAP_RS08110
uniprot id: A1VMR0
names: Similarity
messages: Belongs to the LOG family.

365044:PNAP RS06965
gene id: 365044:PNAP_RS06965
uniprot id: A1VM30
names: Function
names: Similarity
messages: Belongs to the transposase 11 family.
messages: Involved in the transposition of the insertion sequence IS5.

365044:PNAP RS15225
gene id: 365044:PNAP_RS15225
uniprot id: A1VRR5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.

365044:PNAP RS15655
gene id: 365044:PNAP_RS15655
uniprot id: A1VS01
names: Subcellular Location Annotation
messages: Membrane

365044:PNAP RS00365
gene id: 365044:PNAP_RS00365
uniprot id: A1VIB8
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

365044:PNAP RS07145
gene id: 365044:PNAP_RS07145
uniprot id: A1VM67
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

365044:PNAP RS14165
gene id: 365044:PNAP_RS14165
uniprot id: A1VR60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

365044:PNAP RS11965
gene id: 365044:PNAP_RS11965
uniprot id: A1VPX1
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

365044:PNAP RS18040
gene id: 365044:PNAP_RS18040
uniprot id: A1VTD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

365044:PNAP RS02605
gene id: 365044:PNAP_RS02605
uniprot id: A1VJL7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyltransferase 20 family.
messages: Homotetramer.
messages: Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-alpha-D-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor.

365044:PNAP RS14625
gene id: 365044:PNAP_RS14625
uniprot id: A1VRF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

365044:PNAP RS11730
gene id: 365044:PNAP_RS11730
uniprot id: A1VPS4
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the NifH/BchL/ChlL family.
messages: Binds 1 [4Fe-4S] cluster per dimer.
messages: Homodimer.
messages: The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein.
messages: The reversible ADP-ribosylation of Arg inactivates the nitrogenase reductase and regulates nitrogenase activity.
messages: The reversible ADP-ribosylation of Arg-102 inactivates the nitrogenase reductase and regulates nitrogenase activity.

365044:PNAP RS03380
gene id: 365044:PNAP_RS03380
uniprot id: A1VK24
names: Similarity
messages: Belongs to the glutamate synthase family.

365044:PNAP RS09880
gene id: 365044:PNAP_RS09880
uniprot id: A1VNQ2
names: Similarity
messages: Belongs to the peptidase A31 family.

365044:PNAP RS01660
gene id: 365044:PNAP_RS01660
uniprot id: A1VJ31
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

365044:PNAP RS04395
gene id: 365044:PNAP_RS04395
uniprot id: A1VKM3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF1 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

365044:PNAP RS06075
gene id: 365044:PNAP_RS06075
uniprot id: A1VLK0
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

365044:PNAP RS16350
gene id: 365044:PNAP_RS16350
uniprot id: A1VSE8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

365044:PNAP RS11005
gene id: 365044:PNAP_RS11005
uniprot id: A1VPC6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

365044:PNAP RS06420
gene id: 365044:PNAP_RS06420
uniprot id: A1VLR9
names: Cofactor
messages: Binds 3 heme c groups covalently per subunit.

365044:PNAP RS01690
gene id: 365044:PNAP_RS01690
uniprot id: A1VJ38
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

365044:PNAP RS19400
gene id: 365044:PNAP_RS19400
uniprot id: A1VU49
names: Similarity
messages: Belongs to the DprA/Smf family.

365044:PNAP RS17160
gene id: 365044:PNAP_RS17160
uniprot id: A1VSV5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

365044:PNAP RS20450
gene id: 365044:PNAP_RS20450
uniprot id: A1VUR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDT1 family.
messages: Membrane

365044:PNAP RS13120
gene id: 365044:PNAP_RS13120
uniprot id: A1VQK1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial microcompartment
messages: Belongs to the EutC family.
messages: Binds between the large and small subunits.
messages: Catalyzes the deamination of various vicinal amino-alcohols to oxo compounds. Allows this organism to utilize ethanolamine as the sole source of nitrogen and carbon in the presence of external vitamin B12.
messages: The basic unit is a heterodimer which dimerizes to form tetramers. The heterotetramers trimerize; 6 large subunits form a core ring with 6 small subunits projecting outwards.

365044:PNAP RS00050
gene id: 365044:PNAP_RS00050
uniprot id: A1VI55
names: Function
names: Similarity
messages: Belongs to the MinE family.
messages: Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.

365044:PNAP RS12010
gene id: 365044:PNAP_RS12010
uniprot id: A1VPX9
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PSRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.

365044:PNAP RS16975
gene id: 365044:PNAP_RS16975
uniprot id: A1VSR7
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

365044:PNAP RS13550
gene id: 365044:PNAP_RS13550
uniprot id: A1VQT7
names: Subcellular Location Annotation
messages: Membrane

365044:PNAP RS22420
gene id: 365044:PNAP_RS22420
uniprot id: A1VVV7
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

365044:PNAP RS08465
gene id: 365044:PNAP_RS08465
uniprot id: A1VMX9
names: Subcellular Location Annotation
messages: Membrane

365044:PNAP RS16710
gene id: 365044:PNAP_RS16710
uniprot id: A1VSL4
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

365044:PNAP RS11655
gene id: 365044:PNAP_RS11655
uniprot id: A1VPQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell inner membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

365044:PNAP RS15215
gene id: 365044:PNAP_RS15215
uniprot id: A1VRR3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

365044:PNAP RS01920
gene id: 365044:PNAP_RS01920
uniprot id: A1VJ86
names: Similarity
messages: Belongs to the universal stress protein A family.

365044:PNAP RS12005
gene id: 365044:PNAP_RS12005
uniprot id: A1VPX8
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

365044:PNAP RS07975
gene id: 365044:PNAP_RS07975
uniprot id: A1VMN3
names: Similarity
messages: Belongs to the UxaA family.

365044:PNAP RS10620
gene id: 365044:PNAP_RS10620
uniprot id: A1VP48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

365044:PNAP RS00885
gene id: 365044:PNAP_RS00885
uniprot id: A1VIM8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

365044:PNAP RS20090
gene id: 365044:PNAP_RS20090
uniprot id: A1VUJ5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

365044:PNAP RS11525
gene id: 365044:PNAP_RS11525
uniprot id: A1VPN4
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

365044:PNAP RS06715
gene id: 365044:PNAP_RS06715
uniprot id: A1VLX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM175 family.
messages: Membrane

365044:PNAP RS16160
gene id: 365044:PNAP_RS16160
uniprot id: A1VSA9
names: Similarity
messages: Belongs to the GSP E family.

365044:PNAP RS14565
gene id: 365044:PNAP_RS14565
uniprot id: A1VRD9
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

365044:PNAP RS16020
gene id: 365044:PNAP_RS16020
uniprot id: A1VS81
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Essential cell division protein that coordinates cell division and chromosome segregation. The N-terminus is involved in assembly of the cell-division machinery. The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region. Translocation stops specifically at Xer-dif sites, where FtsK interacts with the Xer recombinase, allowing activation of chromosome unlinking by recombination. FtsK orienting polar sequences (KOPS) guide the direction of DNA translocation. FtsK can remove proteins from DNA as it translocates, but translocation stops specifically at XerCD-dif site, thereby preventing removal of XerC and XerD from dif.
messages: Membrane

365044:PNAP RS17690
gene id: 365044:PNAP_RS17690
uniprot id: A1VT63
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

365044:PNAP RS15005
gene id: 365044:PNAP_RS15005
uniprot id: A1VRM1
names: Subcellular Location Annotation
messages: Membrane

365044:PNAP RS17320
gene id: 365044:PNAP_RS17320
uniprot id: A1VSY7
names: Cofactor
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A single active site specifically recognizes both ATP and CTP and is responsible for their addition.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 1 subfamily.
messages: Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases.
messages: Comprises two domains: an N-terminal domain containing the nucleotidyltransferase activity and a C-terminal HD domain associated with both phosphodiesterase and phosphatase activities.
messages: Magnesium is required for nucleotidyltransferase activity.
messages: Monomer. Can also form homodimers and oligomers.
messages: Nickel for phosphatase activity.

365044:PNAP RS14655
gene id: 365044:PNAP_RS14655
uniprot id: A1VRF7
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.

365044:PNAP RS20280
gene id: 365044:PNAP_RS20280
uniprot id: A1VUN1
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20 family.
messages: Binds 2 Zn(2+) ions per subunit.

365044:PNAP RS17425
gene id: 365044:PNAP_RS17425
uniprot id: A1VT09
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

365044:PNAP RS01170
gene id: 365044:PNAP_RS01170
uniprot id: A1VIT5
names: Subcellular Location Annotation
messages: Cytoplasm

365044:PNAP RS24300
gene id: 365044:PNAP_RS24300
uniprot id: A1VWX9
names: Subcellular Location Annotation
messages: Membrane

365044:PNAP RS15015
gene id: 365044:PNAP_RS15015
uniprot id: A1VRM3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

365044:PNAP RS18250
gene id: 365044:PNAP_RS18250
uniprot id: A1VTG9
names: Similarity
names: Subunit
messages: Belongs to the threonine aldolase family.
messages: Homotetramer.

365044:PNAP RS00235
gene id: 365044:PNAP_RS00235
uniprot id: A1VI93
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

365044:PNAP RS01260
gene id: 365044:PNAP_RS01260
uniprot id: A1VIV3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

365044:PNAP RS19210
gene id: 365044:PNAP_RS19210
uniprot id: A1VU13
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acetylates the N-terminal alanine of ribosomal protein S18.
messages: Belongs to the acetyltransferase family. RimI subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

365044:PNAP RS04860
gene id: 365044:PNAP_RS04860
uniprot id: A1VKW2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UreE family.
messages: Cytoplasm
messages: Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly.

365044:PNAP RS07690
gene id: 365044:PNAP_RS07690
uniprot id: A1VMH6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
messages: Belongs to the azoreductase type 1 family.
messages: Binds 1 FMN per subunit.
messages: Homodimer.
messages: Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones.

365044:PNAP RS11585
gene id: 365044:PNAP_RS11585
uniprot id: A1VPP6
names: Function
messages: Could be a 3Fe-4S cluster-containing protein.

365044:PNAP RS10615
gene id: 365044:PNAP_RS10615
uniprot id: A1VP47
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

365044:PNAP RS06535
gene id: 365044:PNAP_RS06535
uniprot id: A1VLU1
names: Caution
names: Function
names: Similarity
messages: Belongs to the globin family. Two-domain flavohemoproteins subfamily.
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

365044:PNAP RS14520
gene id: 365044:PNAP_RS14520
uniprot id: A1VRC9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

365044:PNAP RS19305
gene id: 365044:PNAP_RS19305
uniprot id: A1VU31
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

365044:PNAP RS00915
gene id: 365044:PNAP_RS00915
uniprot id: A1VIN4
names: Similarity
messages: Belongs to the GST superfamily. NadH family.

365044:PNAP RS05390
gene id: 365044:PNAP_RS05390
uniprot id: A1VL70
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

365044:PNAP RS13070
gene id: 365044:PNAP_RS13070
uniprot id: A1VQJ1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

365044:PNAP RS10115
gene id: 365044:PNAP_RS10115
uniprot id: A1VNU9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

365044:PNAP RS22690
gene id: 365044:PNAP_RS22690
uniprot id: A1VW11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

365044:PNAP RS02310
gene id: 365044:PNAP_RS02310
uniprot id: A1VJG0
names: Similarity
messages: Belongs to the UPF0225 family.

365044:PNAP RS13690
gene id: 365044:PNAP_RS13690
uniprot id: A1VQW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpxP/Spy family.
messages: Periplasm

365044:PNAP RS11770
gene id: 365044:PNAP_RS11770
uniprot id: A1VPT2
names: Similarity
messages: Belongs to the OsmC/Ohr family.

365044:PNAP RS09405
gene id: 365044:PNAP_RS09405
uniprot id: A1VNG0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

365044:PNAP RS16015
gene id: 365044:PNAP_RS16015
uniprot id: A1VS80
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LolA family.
messages: Monomer.
messages: Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).
messages: Periplasm

365044:PNAP RS15515
gene id: 365044:PNAP_RS15515
uniprot id: A1VRX4
names: Subcellular Location Annotation
messages: Membrane

365044:PNAP RS09700
gene id: 365044:PNAP_RS09700
uniprot id: A1VNL7
names: Cofactor
messages: Binds 2 Mg(2+) ions per monomer.

365044:PNAP RS03180
gene id: 365044:PNAP_RS03180
uniprot id: A1VJY3
names: Function
names: Similarity
messages: Belongs to the CobT family.
messages: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).

365044:PNAP RS12525
gene id: 365044:PNAP_RS12525
uniprot id: A1VQ85
names: Subcellular Location Annotation
messages: Membrane

365044:PNAP RS01445
gene id: 365044:PNAP_RS01445
uniprot id: A1VIY7
names: Subcellular Location Annotation
messages: Membrane

365044:PNAP RS05890
gene id: 365044:PNAP_RS05890
uniprot id: A1VLG3
names: Similarity
messages: Belongs to the CFA/CMAS family.

365044:PNAP RS07605
gene id: 365044:PNAP_RS07605
uniprot id: A1VMF9
names: Subcellular Location Annotation
messages: Membrane

365044:PNAP RS10025
gene id: 365044:PNAP_RS10025
uniprot id: A1VNT1
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

365044:PNAP RS01630
gene id: 365044:PNAP_RS01630
uniprot id: A1VJ25
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

365044:PNAP RS12105
gene id: 365044:PNAP_RS12105
uniprot id: A1VPZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein SsuA/TauA family.
messages: Periplasm

365044:PNAP RS12380
gene id: 365044:PNAP_RS12380
uniprot id: Q3S4C4
names: Similarity
messages: Belongs to the DapA family.

365044:PNAP RS13710
gene id: 365044:PNAP_RS13710
uniprot id: A1VQW9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

365044:PNAP RS05080
gene id: 365044:PNAP_RS05080
uniprot id: A1VL09
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

365044:PNAP RS18410
gene id: 365044:PNAP_RS18410
uniprot id: A1VTK1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the malate synthase family. GlcB subfamily.
messages: Cytoplasm
messages: Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

365044:PNAP RS03435
gene id: 365044:PNAP_RS03435
uniprot id: A1VK35
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm

365044:PNAP RS11565
gene id: 365044:PNAP_RS11565
uniprot id: A1VPP2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NifW family.
messages: Homotrimer; associates with NifD.
messages: May protect the nitrogenase Fe-Mo protein from oxidative damage.

365044:PNAP RS04770
gene id: 365044:PNAP_RS04770
uniprot id: A1VKU5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate.
messages: Cytoplasm

365044:PNAP RS12195
gene id: 365044:PNAP_RS12195
uniprot id: A1VQ16
names: Similarity
messages: Belongs to the YggT family.

365044:PNAP RS11865
gene id: 365044:PNAP_RS11865
uniprot id: A1VPV1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class II aldolase/RraA-like family.
messages: Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions.
messages: Homotrimer.

365044:PNAP RS10070
gene id: 365044:PNAP_RS10070
uniprot id: A1VNU0
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

365044:PNAP RS09960
gene id: 365044:PNAP_RS09960
uniprot id: A1VNR8
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

365044:PNAP RS05000
gene id: 365044:PNAP_RS05000
uniprot id: A1VKZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UreD family.
messages: Cytoplasm
messages: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
messages: UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

365044:PNAP RS15615
gene id: 365044:PNAP_RS15615
uniprot id: A1VRZ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

365044:PNAP RS19655
gene id: 365044:PNAP_RS19655
uniprot id: A1VUB0
names: Subcellular Location Annotation
messages: Membrane

365044:PNAP RS04865
gene id: 365044:PNAP_RS04865
uniprot id: A1VKW3
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
messages: Binds 2 nickel ions per subunit.
messages: Carboxylation allows a single lysine to coordinate two nickel ions.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

365044:PNAP RS06355
gene id: 365044:PNAP_RS06355
uniprot id: A1VLQ6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Monomer.

365044:PNAP RS20650
gene id: 365044:PNAP_RS20650
uniprot id: A1VUV4
names: Similarity
messages: Belongs to the GST superfamily.

365044:PNAP RS19085
gene id: 365044:PNAP_RS19085
uniprot id: A1VTY8
names: Subcellular Location Annotation
messages: Membrane

365044:PNAP RS17065
gene id: 365044:PNAP_RS17065
uniprot id: A1VST7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. FtsW subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell division.

365044:PNAP RS09090
gene id: 365044:PNAP_RS09090
uniprot id: A1VN98
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

365044:PNAP RS03695
gene id: 365044:PNAP_RS03695
uniprot id: A1VK87
names: Function
names: Similarity
messages: Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
messages: Belongs to the Nudix hydrolase family. RppH subfamily.

365044:PNAP RS04080
gene id: 365044:PNAP_RS04080
uniprot id: A1VKG1
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus
messages: Repair polymerase that plays a key role in base-excision repair. Has 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity that removes the 5' sugar phosphate and also acts as a DNA polymerase that adds one nucleotide to the 3' end of the arising single-nucleotide gap. Conducts 'gap-filling' DNA synthesis in a stepwise distributive fashion rather than in a processive fashion as for other DNA polymerases.

365044:PNAP RS09780
gene id: 365044:PNAP_RS09780
uniprot id: A1VNN2
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.

365044:PNAP RS07865
gene id: 365044:PNAP_RS07865
uniprot id: A1VML2
names: Similarity
messages: Belongs to the HesB/IscA family.

365044:PNAP RS18395
gene id: 365044:PNAP_RS18395
uniprot id: A1VTJ8
names: Cofactor
names: Similarity
messages: Belongs to the monomeric-type IDH family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

365044:PNAP RS19910
gene id: 365044:PNAP_RS19910
uniprot id: A1VUG2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

365044:PNAP RS08085
gene id: 365044:PNAP_RS08085
uniprot id: A1VMQ5
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

365044:PNAP RS12240
gene id: 365044:PNAP_RS12240
uniprot id: A1VQ25
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

365044:PNAP RS01645
gene id: 365044:PNAP_RS01645
uniprot id: A1VJ28
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

365044:PNAP RS10075
gene id: 365044:PNAP_RS10075
uniprot id: A1VNU1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

365044:PNAP RS12045
gene id: 365044:PNAP_RS12045
uniprot id: A1VPY6
names: Similarity
messages: Belongs to the DEAD box helicase family.

365044:PNAP RS08255
gene id: 365044:PNAP_RS08255
uniprot id: A1VMT7
names: Subcellular Location Annotation
messages: Membrane

365044:PNAP RS08620
gene id: 365044:PNAP_RS08620
uniprot id: A1VN10
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

365044:PNAP RS05545
gene id: 365044:PNAP_RS05545
uniprot id: A1VL96
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

365044:PNAP RS04685
gene id: 365044:PNAP_RS04685
uniprot id: A1VKS9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecB family.
messages: Cytoplasm
messages: Homotetramer, a dimer of dimers. One homotetramer interacts with 1 SecA dimer.
messages: One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.

365044:PNAP RS06710
gene id: 365044:PNAP_RS06710
uniprot id: A1VLX6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

365044:PNAP RS22355
gene id: 365044:PNAP_RS22355
uniprot id: A1VVU4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

365044:PNAP RS10585
gene id: 365044:PNAP_RS10585
uniprot id: A1VP40
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

365044:PNAP RS00855
gene id: 365044:PNAP_RS00855
uniprot id: A1VIM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Membrane

365044:PNAP RS01570
gene id: 365044:PNAP_RS01570
uniprot id: A1VJ13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

365044:PNAP RS01650
gene id: 365044:PNAP_RS01650
uniprot id: A1VJ29
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

365044:PNAP RS04385
gene id: 365044:PNAP_RS04385
uniprot id: A1VKM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

365044:PNAP RS09105
gene id: 365044:PNAP_RS09105
uniprot id: A1VNA1
names: Activity Regulation
names: Caution
names: Domain
names: Function
names: Similarity
messages: Belongs to the GlnD family.
messages: Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism.
messages: Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity.

365044:PNAP RS12470
gene id: 365044:PNAP_RS12470
uniprot id: A1VQ73
names: Similarity
messages: Belongs to the GSP E family.

365044:PNAP RS11980
gene id: 365044:PNAP_RS11980
uniprot id: A1VPX4
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

365044:PNAP RS01750
gene id: 365044:PNAP_RS01750
uniprot id: A1VJ49
names: Similarity
messages: Belongs to the peptidase M20 family.

365044:PNAP RS04050
gene id: 365044:PNAP_RS04050
uniprot id: A1VKF6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

365044:PNAP RS19895
gene id: 365044:PNAP_RS19895
uniprot id: A1VUF9
names: Similarity
messages: Belongs to the pirin family.

365044:PNAP RS20525
gene id: 365044:PNAP_RS20525
uniprot id: A1VUT1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

365044:PNAP RS08070
gene id: 365044:PNAP_RS08070
uniprot id: A1VMQ2
names: Subcellular Location Annotation
messages: Membrane

365044:PNAP RS00995
gene id: 365044:PNAP_RS00995
uniprot id: A1VIQ0
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: Methylated by PrmB.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

365044:PNAP RS15295
gene id: 365044:PNAP_RS15295
uniprot id: A1VRS9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

365044:PNAP RS02545
gene id: 365044:PNAP_RS02545
uniprot id: A1VJK5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

365044:PNAP RS15440
gene id: 365044:PNAP_RS15440
uniprot id: A1VRV8
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Involved in a late step of protoheme IX synthesis.
messages: Membrane

365044:PNAP RS07055
gene id: 365044:PNAP_RS07055
uniprot id: A1VM50
names: Similarity
messages: Belongs to the CmpA/NrtA family.

365044:PNAP RS17505
gene id: 365044:PNAP_RS17505
uniprot id: A1VT25
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

365044:PNAP RS02790
gene id: 365044:PNAP_RS02790
uniprot id: A1VJQ4
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

365044:PNAP RS21335
gene id: 365044:PNAP_RS21335
uniprot id: A1VV97
names: Similarity
messages: Belongs to the ParB family.

365044:PNAP RS01045
gene id: 365044:PNAP_RS01045
uniprot id: A1VIR0
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family. Prx5 subfamily.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

365044:PNAP RS17385
gene id: 365044:PNAP_RS17385
uniprot id: A1VT00
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

365044:PNAP RS20310
gene id: 365044:PNAP_RS20310
uniprot id: A1VUN8
names: Domain
names: Function
names: Subcellular Location Annotation
messages: Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation.
messages: Periplasm
messages: The PPIase activity resides only in the second parvulin domain. The N-terminal region and the C-terminal tail are necessary and sufficient for the chaperone activity of SurA. The PPIase activity is dispensable for SurA to function as a chaperone. The N-terminal region and the C-terminal tail are also required for porin recognition.

365044:PNAP RS02195
gene id: 365044:PNAP_RS02195
uniprot id: A1VJD7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

365044:PNAP RS14850
gene id: 365044:PNAP_RS14850
uniprot id: A1VRJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

365044:PNAP RS17365
gene id: 365044:PNAP_RS17365
uniprot id: A1VSZ6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

365044:PNAP RS12300
gene id: 365044:PNAP_RS12300
uniprot id: A1VQ37
names: Subcellular Location Annotation
messages: Membrane

365044:PNAP RS02740
gene id: 365044:PNAP_RS02740
uniprot id: A1VJP3
names: Subcellular Location Annotation
messages: Membrane

365044:PNAP RS08500
gene id: 365044:PNAP_RS08500
uniprot id: A1VMY6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-insensitive subfamily.
messages: Cell inner membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force.

365044:PNAP RS14400
gene id: 365044:PNAP_RS14400
uniprot id: A1VRA5
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

365044:PNAP RS08660
gene id: 365044:PNAP_RS08660
uniprot id: A1VN18
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

365044:PNAP RS07305
gene id: 365044:PNAP_RS07305
uniprot id: A1VM99
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

365044:PNAP RS06370
gene id: 365044:PNAP_RS06370
uniprot id: A1VLQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

365044:PNAP RS14925
gene id: 365044:PNAP_RS14925
uniprot id: A1VRK5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the glyoxalase I family.
messages: Binds 1 nickel ion per subunit.
messages: Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.

365044:PNAP RS20215
gene id: 365044:PNAP_RS20215
uniprot id: A1VUL8
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

365044:PNAP RS06220
gene id: 365044:PNAP_RS06220
uniprot id: A1VLM9
names: Subcellular Location Annotation
messages: Membrane

365044:PNAP RS07115
gene id: 365044:PNAP_RS07115
uniprot id: A1VM61
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity).

365044:PNAP RS10850
gene id: 365044:PNAP_RS10850
uniprot id: A1VP93
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

365044:PNAP RS03310
gene id: 365044:PNAP_RS03310
uniprot id: A1VK09
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MsrQ family.
messages: Binds 1 FMN per subunit.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Cell inner membrane
messages: Heterodimer of a catalytic subunit (MsrP) and a heme-binding subunit (MsrQ).
messages: Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain.

365044:PNAP RS04180
gene id: 365044:PNAP_RS04180
uniprot id: A1VKI0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

365044:PNAP RS04115
gene id: 365044:PNAP_RS04115
uniprot id: A1VKG8
names: Similarity
messages: Belongs to the peptidase C40 family.

365044:PNAP RS14180
gene id: 365044:PNAP_RS14180
uniprot id: A1VR63
names: Subcellular Location Annotation
messages: Membrane

365044:PNAP RS08850
gene id: 365044:PNAP_RS08850
uniprot id: A1VN50
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

365044:PNAP RS02030
gene id: 365044:PNAP_RS02030
uniprot id: A1VJA8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCF family. Uup subfamily.
messages: Cytoplasm
messages: Probably plays a role in ribosome assembly or function. May be involved in resolution of branched DNA intermediates that result from template switching in postreplication gaps. Binds DNA and has ATPase activity.

365044:PNAP RS07050
gene id: 365044:PNAP_RS07050
uniprot id: A1VM49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

365044:PNAP RS03825
gene id: 365044:PNAP_RS03825
uniprot id: A1VKB2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA gyrase inhibitor YacG family.
messages: Binds 1 zinc ion.
messages: Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.
messages: Interacts with GyrB.

365044:PNAP RS04100
gene id: 365044:PNAP_RS04100
uniprot id: A1VKG6
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

365044:PNAP RS14955
gene id: 365044:PNAP_RS14955
uniprot id: A1VRL1
names: Function
names: Similarity
messages: Belongs to the HPPK family.
messages: Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.

365044:PNAP RS11025
gene id: 365044:PNAP_RS11025
uniprot id: A1VPD0
names: Function
messages: Member of the two-component regulatory system PhoR/PhoB involved in the phosphate regulon genes expression. PhoR may function as a membrane-associated protein kinase that phosphorylates PhoB in response to environmental signals.

365044:PNAP RS19355
gene id: 365044:PNAP_RS19355
uniprot id: A1VU41
names: Similarity
messages: Belongs to the pyruvate kinase family.

365044:PNAP RS08835
gene id: 365044:PNAP_RS08835
uniprot id: A1VN47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

365044:PNAP RS03175
gene id: 365044:PNAP_RS03175
uniprot id: A1VJY2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell inner membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.

365044:PNAP RS05130
gene id: 365044:PNAP_RS05130
uniprot id: A1VL19
names: Similarity
messages: Belongs to the ABC transporter superfamily.

365044:PNAP RS12860
gene id: 365044:PNAP_RS12860
uniprot id: A1VQE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

365044:PNAP RS02500
gene id: 365044:PNAP_RS02500
uniprot id: A1VJJ6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the helicase family. DinG subfamily. Type 1 sub-subfamily.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA-dependent ATPase and 5'-3' DNA helicase.

365044:PNAP RS13925
gene id: 365044:PNAP_RS13925
uniprot id: A1VR12
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
messages: O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.

365044:PNAP RS03430
gene id: 365044:PNAP_RS03430
uniprot id: A1VK34
names: Similarity
messages: Belongs to the BolA/IbaG family.

365044:PNAP RS14360
gene id: 365044:PNAP_RS14360
uniprot id: A1VR97
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

365044:PNAP RS00665
gene id: 365044:PNAP_RS00665
uniprot id: A1VII1
names: Similarity
messages: Belongs to the HepT RNase toxin family.

365044:PNAP RS20925
gene id: 365044:PNAP_RS20925
uniprot id: A1VV08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrbI/VirB10 family.
messages: Membrane

365044:PNAP RS00485
gene id: 365044:PNAP_RS00485
uniprot id: A1VIE4
names: Subcellular Location Annotation
messages: Membrane

365044:PNAP RS08090
gene id: 365044:PNAP_RS08090
uniprot id: A1VMQ6
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

365044:PNAP RS20475
gene id: 365044:PNAP_RS20475
uniprot id: A1VUS0
names: Similarity
messages: Belongs to the SIS family. GutQ/KpsF subfamily.

365044:PNAP RS02440
gene id: 365044:PNAP_RS02440
uniprot id: A1VJI4
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

365044:PNAP RS06005
gene id: 365044:PNAP_RS06005
uniprot id: A1VLI6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family. ParE type 1 subfamily.
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

365044:PNAP RS11625
gene id: 365044:PNAP_RS11625
uniprot id: A1VPQ4
names: Function
names: Similarity
messages: Belongs to the NifD/NifK/NifE/NifN family.
messages: This protein may play a role in the biosynthesis of the prosthetic group of nitrogenase (FeMo cofactor).

365044:PNAP RS01310
gene id: 365044:PNAP_RS01310
uniprot id: A1VIW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

365044:PNAP RS10560
gene id: 365044:PNAP_RS10560
uniprot id: A1VP35
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. Nitrilase family.

365044:PNAP RS05625
gene id: 365044:PNAP_RS05625
uniprot id: A1VLB1
names: Similarity
messages: Belongs to the HMG-CoA lyase family.
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

365044:PNAP RS11875
gene id: 365044:PNAP_RS11875
uniprot id: A1VPV3
names: Similarity
messages: Belongs to the DODA-type extradiol aromatic ring-opening dioxygenase family.

365044:PNAP RS11650
gene id: 365044:PNAP_RS11650
uniprot id: A1VPQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

365044:PNAP RS00405
gene id: 365044:PNAP_RS00405
uniprot id: A1VIC8
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

365044:PNAP RS22100
gene id: 365044:PNAP_RS22100
uniprot id: A1VVQ0
names: Similarity
messages: Belongs to the RelB/DinJ antitoxin family.

365044:PNAP RS17300
gene id: 365044:PNAP_RS17300
uniprot id: A1VSY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Cell inner membrane
messages: Membrane

365044:PNAP RS20325
gene id: 365044:PNAP_RS20325
uniprot id: A1VUP1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

365044:PNAP RS02625
gene id: 365044:PNAP_RS02625
uniprot id: A1VJM1
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

365044:PNAP RS08540
gene id: 365044:PNAP_RS08540
uniprot id: A1VMZ4
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

365044:PNAP RS15925
gene id: 365044:PNAP_RS15925
uniprot id: A1VS61
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. Fucose synthase subfamily.
messages: Catalyzes the two-step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.

365044:PNAP RS00075
gene id: 365044:PNAP_RS00075
uniprot id: A1VI61
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase D family. Cardiolipin synthase subfamily. ClsB sub-subfamily.
messages: Catalyzes the phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
messages: Cell membrane

365044:PNAP RS08830
gene id: 365044:PNAP_RS08830
uniprot id: A1VN46
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

365044:PNAP RS20520
gene id: 365044:PNAP_RS20520
uniprot id: A1VUT0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

365044:PNAP RS00255
gene id: 365044:PNAP_RS00255
uniprot id: A1VI97
names: Similarity
messages: Belongs to the AOR/FOR family.

365044:PNAP RS15620
gene id: 365044:PNAP_RS15620
uniprot id: A1VRZ4
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

365044:PNAP RS03020
gene id: 365044:PNAP_RS03020
uniprot id: A1VJV0
names: Subcellular Location Annotation
messages: Membrane

365044:PNAP RS04325
gene id: 365044:PNAP_RS04325
uniprot id: A1VKK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

365044:PNAP RS17190
gene id: 365044:PNAP_RS17190
uniprot id: A1VSW1
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

365044:PNAP RS02795
gene id: 365044:PNAP_RS02795
uniprot id: A1VJQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic sulfate-binding protein family.
messages: Periplasm

365044:PNAP RS15370
gene id: 365044:PNAP_RS15370
uniprot id: A1VRU4
names: Similarity
messages: Belongs to the fabD family.

365044:PNAP RS22475
gene id: 365044:PNAP_RS22475
uniprot id: A1VVW8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.
messages: Homotetramer.
messages: Uses inorganic polyphosphate (polyP) as a donor to convert GDP to GTP or ADP to ATP.

365044:PNAP RS14935
gene id: 365044:PNAP_RS14935
uniprot id: A1VRK7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Catalyzes the dehydration of 6-phospho-D-gluconate to 2-dehydro-3-deoxy-6-phospho-D-gluconate.

365044:PNAP RS18810
gene id: 365044:PNAP_RS18810
uniprot id: A1VTT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Membrane

365044:PNAP RS05095
gene id: 365044:PNAP_RS05095
uniprot id: A1VL12
names: Similarity
messages: Belongs to the TPP enzyme family.

365044:PNAP RS09425
gene id: 365044:PNAP_RS09425
uniprot id: A1VNG4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
messages: This function is generally fulfilled by the C-terminal part of HisG, which is missing in some bacteria such as this one.

365044:PNAP RS00595
gene id: 365044:PNAP_RS00595
uniprot id: A1VIG7
names: Similarity
messages: Belongs to the P(II) protein family.

365044:PNAP RS20535
gene id: 365044:PNAP_RS20535
uniprot id: A1VUT3
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

365044:PNAP RS10360
gene id: 365044:PNAP_RS10360
uniprot id: A1VNZ5
names: Subcellular Location Annotation
messages: Membrane

365044:PNAP RS17800
gene id: 365044:PNAP_RS17800
uniprot id: A1VT85
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

365044:PNAP RS18855
gene id: 365044:PNAP_RS18855
uniprot id: A1VTU0
names: Cofactor
names: Similarity
messages: Belongs to the arginase family.
messages: Binds 2 manganese ions per subunit.

365044:PNAP RS07745
gene id: 365044:PNAP_RS07745
uniprot id: A1VMI7
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

365044:PNAP RS10480
gene id: 365044:PNAP_RS10480
uniprot id: A1VP19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

365044:PNAP RS09615
gene id: 365044:PNAP_RS09615
uniprot id: A1VNK0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

365044:PNAP RS00865
gene id: 365044:PNAP_RS00865
uniprot id: A1VIM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

365044:PNAP RS05630
gene id: 365044:PNAP_RS05630
uniprot id: A1VLB2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

365044:PNAP RS10305
gene id: 365044:PNAP_RS10305
uniprot id: A1VNY4
names: Subcellular Location Annotation
messages: Membrane

365044:PNAP RS19330
gene id: 365044:PNAP_RS19330
uniprot id: A1VU36
names: Similarity
messages: Belongs to the SAICAR synthetase family.

365044:PNAP RS00325
gene id: 365044:PNAP_RS00325
uniprot id: A1VIB0
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

365044:PNAP RS17070
gene id: 365044:PNAP_RS17070
uniprot id: A1VST8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

365044:PNAP RS19705
gene id: 365044:PNAP_RS19705
uniprot id: A1VUC0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

365044:PNAP RS21410
gene id: 365044:PNAP_RS21410
uniprot id: A1VVA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta sliding clamp family.
messages: Cytoplasm

365044:PNAP RS10135
gene id: 365044:PNAP_RS10135
uniprot id: A1VNV3
names: Similarity
messages: Belongs to the band 7/mec-2 family.

365044:PNAP RS05775
gene id: 365044:PNAP_RS05775
uniprot id: A1VLE1
names: Subcellular Location Annotation
messages: Membrane

365044:PNAP RS00600
gene id: 365044:PNAP_RS00600
uniprot id: A1VIG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

365044:PNAP RS03440
gene id: 365044:PNAP_RS03440
uniprot id: A1VK36
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Lacks the C-terminal regulatory region which is replaced by HisZ.

365044:PNAP RS08400
gene id: 365044:PNAP_RS08400
uniprot id: A1VMW6
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

365044:PNAP RS20640
gene id: 365044:PNAP_RS20640
uniprot id: A1VUV2
names: Similarity
messages: Belongs to the acetaldehyde dehydrogenase family.

365044:PNAP RS09185
gene id: 365044:PNAP_RS09185
uniprot id: A1VNB7
names: Cofactor
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Binds 1 zinc ion per subunit. The zinc ion is important for the structural integrity of the protein.

365044:PNAP RS14790
gene id: 365044:PNAP_RS14790
uniprot id: A1VRH9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

365044:PNAP RS13570
gene id: 365044:PNAP_RS13570
uniprot id: A1VQU1
names: Similarity
messages: Belongs to the leucine-binding protein family.

365044:PNAP RS11105
gene id: 365044:PNAP_RS11105
uniprot id: A1VPE6
names: Subcellular Location Annotation
messages: Membrane

365044:PNAP RS13945
gene id: 365044:PNAP_RS13945
uniprot id: A1VR16
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.

365044:PNAP RS18000
gene id: 365044:PNAP_RS18000
uniprot id: A1VTC4
names: Similarity
messages: Belongs to the leucine-binding protein family.

365044:PNAP RS21235
gene id: 365044:PNAP_RS21235
uniprot id: A1VV76
names: Similarity
messages: Belongs to the heat shock protein 70 family.

365044:PNAP RS17970
gene id: 365044:PNAP_RS17970
uniprot id: A1VTB9
names: Subcellular Location Annotation
messages: Membrane

365044:PNAP RS03470
gene id: 365044:PNAP_RS03470
uniprot id: A1VK42
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

365044:PNAP RS18200
gene id: 365044:PNAP_RS18200
uniprot id: A1VTG3
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

365044:PNAP RS17430
gene id: 365044:PNAP_RS17430
uniprot id: A1VT10
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

365044:PNAP RS20470
gene id: 365044:PNAP_RS20470
uniprot id: A1VUR9
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Homotetramer.

365044:PNAP RS12780
gene id: 365044:PNAP_RS12780
uniprot id: A1VQD2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterioferritin family.
messages: Iron-storage protein.
messages: Oligomer of 24 subunits, arranged as 12 dimers, that are packed together to form an approximately spherical molecule with a central cavity, in which large amounts of iron can be deposited.

365044:PNAP RS04650
gene id: 365044:PNAP_RS04650
uniprot id: A1VKS2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

365044:PNAP RS13280
gene id: 365044:PNAP_RS13280
uniprot id: A1VQN2
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit A family.

365044:PNAP RS03450
gene id: 365044:PNAP_RS03450
uniprot id: A1VK38
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

365044:PNAP RS19065
gene id: 365044:PNAP_RS19065
uniprot id: A1VTY4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

365044:PNAP RS01790
gene id: 365044:PNAP_RS01790
uniprot id: A1VJ58
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.

365044:PNAP RS08100
gene id: 365044:PNAP_RS08100
uniprot id: A1VMQ8
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

365044:PNAP RS03750
gene id: 365044:PNAP_RS03750
uniprot id: A1VK97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial secretin family. GSP D subfamily.
messages: Cell outer membrane

365044:PNAP RS03715
gene id: 365044:PNAP_RS03715
uniprot id: A1VK91
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

365044:PNAP RS08485
gene id: 365044:PNAP_RS08485
uniprot id: A1VMY3
names: Similarity
messages: Belongs to the IlvD/Edd family.

365044:PNAP RS17045
gene id: 365044:PNAP_RS17045
uniprot id: A1VST3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsQ/DivIB family. FtsQ subfamily.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly.
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

365044:PNAP RS01785
gene id: 365044:PNAP_RS01785
uniprot id: A1VJ57
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

365044:PNAP RS04520
gene id: 365044:PNAP_RS04520
uniprot id: A1VKP7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.

365044:PNAP RS07165
gene id: 365044:PNAP_RS07165
uniprot id: A1VM71
names: Subcellular Location Annotation
messages: Membrane

365044:PNAP RS13915
gene id: 365044:PNAP_RS13915
uniprot id: A1VR10
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

365044:PNAP RS03495
gene id: 365044:PNAP_RS03495
uniprot id: A1VK47
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell inner membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

365044:PNAP RS03570
gene id: 365044:PNAP_RS03570
uniprot id: A1VK61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

365044:PNAP RS06160
gene id: 365044:PNAP_RS06160
uniprot id: A1VLL7
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.

365044:PNAP RS05420
gene id: 365044:PNAP_RS05420
uniprot id: A1VL76
names: Similarity
messages: Belongs to the ArsC family.

365044:PNAP RS24700
gene id: 365044:PNAP_RS24700
uniprot id: A1VX61
names: Similarity
messages: Belongs to the site-specific recombinase resolvase family.

365044:PNAP RS03960
gene id: 365044:PNAP_RS03960
uniprot id: A1VKD8
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

365044:PNAP RS17040
gene id: 365044:PNAP_RS17040
uniprot id: A1VST2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell inner membrane
messages: Self-interacts. Interacts with FtsZ.

365044:PNAP RS11660
gene id: 365044:PNAP_RS11660
uniprot id: A1VPR0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase C chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

365044:PNAP RS11725
gene id: 365044:PNAP_RS11725
uniprot id: A1VPS3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NifD/NifK/NifE/NifN family.
messages: Tetramer of two alpha and two beta chains. Forms complex with the iron protein (nitrogenase component 2).
messages: This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation.

365044:PNAP RS04945
gene id: 365044:PNAP_RS04945
uniprot id: A1VKY0
names: Similarity
messages: Belongs to the band 7/mec-2 family.

365044:PNAP RS03800
gene id: 365044:PNAP_RS03800
uniprot id: A1VKA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP E family.
messages: Cytoplasm

365044:PNAP RS14235
gene id: 365044:PNAP_RS14235
uniprot id: A1VR72
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

365044:PNAP RS02200
gene id: 365044:PNAP_RS02200
uniprot id: A1VJD8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

365044:PNAP RS14250
gene id: 365044:PNAP_RS14250
uniprot id: A1VR75
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

365044:PNAP RS07065
gene id: 365044:PNAP_RS07065
uniprot id: A1VM52
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

365044:PNAP RS12210
gene id: 365044:PNAP_RS12210
uniprot id: A1VQ18
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
messages: Cytoplasm

365044:PNAP RS10335
gene id: 365044:PNAP_RS10335
uniprot id: A1VNZ0
names: Similarity
messages: Belongs to the SUI1 family.

365044:PNAP RS18785
gene id: 365044:PNAP_RS18785
uniprot id: A1VTS6
names: Subcellular Location Annotation
messages: Membrane

365044:PNAP RS09635
gene id: 365044:PNAP_RS09635
uniprot id: A1VNK4
names: Similarity
messages: Belongs to the UPF0434 family.

365044:PNAP RS22600
gene id: 365044:PNAP_RS22600
uniprot id: A1VVZ5
names: Subcellular Location Annotation
messages: Periplasm

365044:PNAP RS15580
gene id: 365044:PNAP_RS15580
uniprot id: A1VRY7
names: Similarity
messages: Belongs to the polysaccharide synthase family.

365044:PNAP RS07410
gene id: 365044:PNAP_RS07410
uniprot id: A1VMC0
names: Subcellular Location Annotation
messages: Membrane

365044:PNAP RS08615
gene id: 365044:PNAP_RS08615
uniprot id: A1VN09
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the R-transferase family. Bpt subfamily.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate.

365044:PNAP RS13160
gene id: 365044:PNAP_RS13160
uniprot id: A1VQK9
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

365044:PNAP RS13275
gene id: 365044:PNAP_RS13275
uniprot id: A1VQN1
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

365044:PNAP RS06525
gene id: 365044:PNAP_RS06525
uniprot id: A1VLT9
names: Caution
names: Function
names: Similarity
messages: Belongs to the Dus family. DusC subfamily.
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U16 in tRNAs.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

365044:PNAP RS00275
gene id: 365044:PNAP_RS00275
uniprot id: A1VIA1
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

365044:PNAP RS16765
gene id: 365044:PNAP_RS16765
uniprot id: A1VSM6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

365044:PNAP RS08650
gene id: 365044:PNAP_RS08650
uniprot id: A1VN16
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein L14 (rplN).

365044:PNAP RS15825
gene id: 365044:PNAP_RS15825
uniprot id: A1VS36
names: Similarity
messages: Belongs to the UPF0246 family.

365044:PNAP RS03365
gene id: 365044:PNAP_RS03365
uniprot id: A1VK21
names: Similarity
messages: Belongs to the dGTPase family. Type 2 subfamily.

365044:PNAP RS00940
gene id: 365044:PNAP_RS00940
uniprot id: A1VIN9
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

365044:PNAP RS05510
gene id: 365044:PNAP_RS05510
uniprot id: A1VL89
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

365044:PNAP RS01250
gene id: 365044:PNAP_RS01250
uniprot id: A1VIV1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

365044:PNAP RS03630
gene id: 365044:PNAP_RS03630
uniprot id: A1VK74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S33 family.
messages: Cytoplasm

365044:PNAP RS02875
gene id: 365044:PNAP_RS02875
uniprot id: A1VJS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

365044:PNAP RS02165
gene id: 365044:PNAP_RS02165
uniprot id: A1VJD1
names: Subcellular Location Annotation
messages: Membrane

365044:PNAP RS02910
gene id: 365044:PNAP_RS02910
uniprot id: A1VJS8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmE/CycJ family.
messages: Cell inner membrane
messages: Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.

365044:PNAP RS02515
gene id: 365044:PNAP_RS02515
uniprot id: A1VJJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

365044:PNAP RS06070
gene id: 365044:PNAP_RS06070
uniprot id: A1VLJ9
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

365044:PNAP RS20340
gene id: 365044:PNAP_RS20340
uniprot id: A1VUP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

365044:PNAP RS18665
gene id: 365044:PNAP_RS18665
uniprot id: A1VTQ1
names: Similarity
messages: Belongs to the 4-oxalocrotonate tautomerase family.

365044:PNAP RS19190
gene id: 365044:PNAP_RS19190
uniprot id: A1VU09
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

365044:PNAP RS17275
gene id: 365044:PNAP_RS17275
uniprot id: A1VSX8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

365044:PNAP RS15810
gene id: 365044:PNAP_RS15810
uniprot id: A1VS33
names: Subcellular Location Annotation
messages: Periplasm

365044:PNAP RS15100
gene id: 365044:PNAP_RS15100
uniprot id: A1VRP0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the kynureninase family.
messages: Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
messages: Homodimer.

365044:PNAP RS20495
gene id: 365044:PNAP_RS20495
uniprot id: A1VUS4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.

365044:PNAP RS19520
gene id: 365044:PNAP_RS19520
uniprot id: A1VU74
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

365044:PNAP RS07800
gene id: 365044:PNAP_RS07800
uniprot id: A1VMJ8
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

365044:PNAP RS00335
gene id: 365044:PNAP_RS00335
uniprot id: A1VIB2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.

365044:PNAP RS17415
gene id: 365044:PNAP_RS17415
uniprot id: A1VT07
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

365044:PNAP RS18205
gene id: 365044:PNAP_RS18205
uniprot id: A1VTG4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

365044:PNAP RS20305
gene id: 365044:PNAP_RS20305
uniprot id: A1VUN7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

365044:PNAP RS08470
gene id: 365044:PNAP_RS08470
uniprot id: A1VMY0
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

365044:PNAP RS19380
gene id: 365044:PNAP_RS19380
uniprot id: A1VU46
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

365044:PNAP RS07370
gene id: 365044:PNAP_RS07370
uniprot id: A1VMB2
names: Similarity
messages: Belongs to the pseudomonas-type ThrB family.

365044:PNAP RS19375
gene id: 365044:PNAP_RS19375
uniprot id: A1VU45
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

365044:PNAP RS22480
gene id: 365044:PNAP_RS22480
uniprot id: A1VVW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

365044:PNAP RS20085
gene id: 365044:PNAP_RS20085
uniprot id: A1VUJ4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

365044:PNAP RS19080
gene id: 365044:PNAP_RS19080
uniprot id: A1VTY7
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

365044:PNAP RS16345
gene id: 365044:PNAP_RS16345
uniprot id: A1VSE7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Cell membrane
messages: Membrane

365044:PNAP RS00970
gene id: 365044:PNAP_RS00970
uniprot id: A1VIP5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

365044:PNAP RS15205
gene id: 365044:PNAP_RS15205
uniprot id: A1VRR1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

365044:PNAP RS03150
gene id: 365044:PNAP_RS03150
uniprot id: A1VJX7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

365044:PNAP RS11510
gene id: 365044:PNAP_RS11510
uniprot id: A1VPN1
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

365044:PNAP RS12840
gene id: 365044:PNAP_RS12840
uniprot id: A1VQE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

365044:PNAP RS10040
gene id: 365044:PNAP_RS10040
uniprot id: A1VNT4
names: Similarity
messages: Belongs to the UPF0125 (RnfH) family.

365044:PNAP RS10380
gene id: 365044:PNAP_RS10380
uniprot id: A1VNZ9
names: Similarity
messages: Belongs to the UxaA family.

365044:PNAP RS07110
gene id: 365044:PNAP_RS07110
uniprot id: A1VM60
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

365044:PNAP RS23605
gene id: 365044:PNAP_RS23605
uniprot id: A1VWJ4
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

365044:PNAP RS00095
gene id: 365044:PNAP_RS00095
uniprot id: A1VI65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpxP/Spy family.
messages: Periplasm

365044:PNAP RS12950
gene id: 365044:PNAP_RS12950
uniprot id: A1VQG6
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

365044:PNAP RS18070
gene id: 365044:PNAP_RS18070
uniprot id: A1VTD8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

365044:PNAP RS05530
gene id: 365044:PNAP_RS05530
uniprot id: A1VL93
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

365044:PNAP RS12405
gene id: 365044:PNAP_RS12405
uniprot id: A1VQ60
names: Similarity
messages: Belongs to the bacterial ring-hydroxylating dioxygenase beta subunit family.

365044:PNAP RS10400
gene id: 365044:PNAP_RS10400
uniprot id: A1VP03
names: Similarity
messages: Belongs to the ABC transporter superfamily.

365044:PNAP RS07840
gene id: 365044:PNAP_RS07840
uniprot id: A1VMK6
names: Function
names: Subunit
messages: Interacts with sigma-54.
messages: Required for activation of most nif operons, which are directly involved in nitrogen fixation.

365044:PNAP RS13935
gene id: 365044:PNAP_RS13935
uniprot id: A1VR14
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

365044:PNAP RS17470
gene id: 365044:PNAP_RS17470
uniprot id: A1VT18
names: Subcellular Location Annotation
messages: Membrane

365044:PNAP RS18405
gene id: 365044:PNAP_RS18405
uniprot id: A1VTK0
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

365044:PNAP RS00070
gene id: 365044:PNAP_RS00070
uniprot id: A1VI60
names: Subcellular Location Annotation
messages: Membrane

365044:PNAP RS11050
gene id: 365044:PNAP_RS11050
uniprot id: A1VPD5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

365044:PNAP RS01275
gene id: 365044:PNAP_RS01275
uniprot id: A1VIV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

365044:PNAP RS14245
gene id: 365044:PNAP_RS14245
uniprot id: A1VR74
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

365044:PNAP RS19750
gene id: 365044:PNAP_RS19750
uniprot id: A1VUC9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ApbE family.
messages: Cell inner membrane
messages: Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.
messages: Magnesium. Can also use manganese.

365044:PNAP RS19050
gene id: 365044:PNAP_RS19050
uniprot id: A1VTY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

365044:PNAP RS00840
gene id: 365044:PNAP_RS00840
uniprot id: A1VIL9
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

365044:PNAP RS10195
gene id: 365044:PNAP_RS10195
uniprot id: A1VNW5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

365044:PNAP RS19000
gene id: 365044:PNAP_RS19000
uniprot id: A1VTX0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

365044:PNAP RS22545
gene id: 365044:PNAP_RS22545
uniprot id: A1VVY5
names: Subcellular Location Annotation
messages: Membrane

365044:PNAP RS17350
gene id: 365044:PNAP_RS17350
uniprot id: A1VSZ3
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

365044:PNAP RS07590
gene id: 365044:PNAP_RS07590
uniprot id: A1VMF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

365044:PNAP RS06165
gene id: 365044:PNAP_RS06165
uniprot id: A1VLL8
names: Similarity
messages: Belongs to the HSP15 family.

365044:PNAP RS01145
gene id: 365044:PNAP_RS01145
uniprot id: A1VIT0
names: Similarity
messages: Belongs to the universal stress protein A family.

365044:PNAP RS15095
gene id: 365044:PNAP_RS15095
uniprot id: A1VRN9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Cyclase 1 superfamily. KynB family.
messages: Binds 2 zinc ions per subunit.
messages: Catalyzes the hydrolysis of N-formyl-L-kynurenine to L-kynurenine, the second step in the kynurenine pathway of tryptophan degradation.
messages: Homodimer.

365044:PNAP RS05395
gene id: 365044:PNAP_RS05395
uniprot id: A1VL71
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 2 subfamily.
messages: Cytoplasm
messages: Homotetramer.

365044:PNAP RS02925
gene id: 365044:PNAP_RS02925
uniprot id: A1VJT0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmB/CycW/HelB family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

365044:PNAP RS10595
gene id: 365044:PNAP_RS10595
uniprot id: A1VP42
names: Similarity
messages: Belongs to the bacterial ring-hydroxylating dioxygenase beta subunit family.

365044:PNAP RS04510
gene id: 365044:PNAP_RS04510
uniprot id: A1VKP5
names: Function
names: Similarity
messages: Belongs to the RapZ-like family.
messages: Displays ATPase and GTPase activities.

365044:PNAP RS06805
gene id: 365044:PNAP_RS06805
uniprot id: A1VLZ8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

365044:PNAP RS04515
gene id: 365044:PNAP_RS04515
uniprot id: A1VKP6
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

365044:PNAP RS03845
gene id: 365044:PNAP_RS03845
uniprot id: A1VKB6
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

365044:PNAP RS05685
gene id: 365044:PNAP_RS05685
uniprot id: A1VLC3
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

365044:PNAP RS11605
gene id: 365044:PNAP_RS11605
uniprot id: A1VPQ0
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

365044:PNAP RS02905
gene id: 365044:PNAP_RS02905
uniprot id: A1VJS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
messages: Cell inner membrane
messages: Membrane

365044:PNAP RS08900
gene id: 365044:PNAP_RS08900
uniprot id: A1VN60
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

365044:PNAP RS13960
gene id: 365044:PNAP_RS13960
uniprot id: A1VR19
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

365044:PNAP RS04465
gene id: 365044:PNAP_RS04465
uniprot id: A1VKN7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

365044:PNAP RS27920
gene id: 365044:PNAP_RS27920
uniprot id: A1VQC4
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

365044:PNAP RS01000
gene id: 365044:PNAP_RS01000
uniprot id: A1VIQ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

365044:PNAP RS01330
gene id: 365044:PNAP_RS01330
uniprot id: A1VIW6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

365044:PNAP RS22415
gene id: 365044:PNAP_RS22415
uniprot id: A1VVV6
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

365044:PNAP RS14615
gene id: 365044:PNAP_RS14615
uniprot id: A1VRE9
names: Similarity
messages: Belongs to the pirin family.

365044:PNAP RS08440
gene id: 365044:PNAP_RS08440
uniprot id: A1VMX4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

365044:PNAP RS16835
gene id: 365044:PNAP_RS16835
uniprot id: A1VSN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0073 (Hly-III) family.
messages: Membrane

365044:PNAP RS10630
gene id: 365044:PNAP_RS10630
uniprot id: A1VP50
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family.

365044:PNAP RS18160
gene id: 365044:PNAP_RS18160
uniprot id: A1VTF5
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

365044:PNAP RS07830
gene id: 365044:PNAP_RS07830
uniprot id: A1VMK4
names: Function
names: Similarity
messages: A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.
messages: Belongs to the NifU family.

365044:PNAP RS15125
gene id: 365044:PNAP_RS15125
uniprot id: A1VRP5
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.

365044:PNAP RS01635
gene id: 365044:PNAP_RS01635
uniprot id: A1VJ26
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

365044:PNAP RS17375
gene id: 365044:PNAP_RS17375
uniprot id: A1VSZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

365044:PNAP RS19420
gene id: 365044:PNAP_RS19420
uniprot id: A1VU53
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

365044:PNAP RS08010
gene id: 365044:PNAP_RS08010
uniprot id: A1VMP0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

365044:PNAP RS19665
gene id: 365044:PNAP_RS19665
uniprot id: A1VUB3
names: Similarity
messages: Belongs to the N-Me-Phe pilin family.

365044:PNAP RS07010
gene id: 365044:PNAP_RS07010
uniprot id: A1VM40
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.

365044:PNAP RS17095
gene id: 365044:PNAP_RS17095
uniprot id: A1VSU3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsL family.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
messages: Membrane
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

365044:PNAP RS16245
gene id: 365044:PNAP_RS16245
uniprot id: A1VSC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

365044:PNAP RS06930
gene id: 365044:PNAP_RS06930
uniprot id: A1VM21
names: Similarity
messages: Belongs to the peptidase U62 family.

365044:PNAP RS03455
gene id: 365044:PNAP_RS03455
uniprot id: A1VK39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

365044:PNAP RS04255
gene id: 365044:PNAP_RS04255
uniprot id: A1VKJ5
names: Subcellular Location Annotation
messages: Membrane

365044:PNAP RS12190
gene id: 365044:PNAP_RS12190
uniprot id: A1VQ15
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

365044:PNAP RS06150
gene id: 365044:PNAP_RS06150
uniprot id: A1VLL5
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

365044:PNAP RS14010
gene id: 365044:PNAP_RS14010
uniprot id: A1VR29
names: Subcellular Location Annotation
messages: Cytoplasm

365044:PNAP RS02565
gene id: 365044:PNAP_RS02565
uniprot id: A1VJK9
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TtcA family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is chelated by three Cys residues, the fourth Fe has a free coordination site that may bind a sulfur atom transferred from the persulfide of IscS.
messages: Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
messages: Cytoplasm
messages: Homodimer.
messages: The thiolation reaction likely consists of two steps: a first activation step by ATP to form an adenylated intermediate of the target base of tRNA, and a second nucleophilic substitution step of the sulfur (S) atom supplied by the hydrosulfide attached to the Fe-S cluster.

365044:PNAP RS03780
gene id: 365044:PNAP_RS03780
uniprot id: A1VKA3
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GSP I family.
messages: Cell inner membrane
messages: Cleaved by prepilin peptidase.
messages: Component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.
messages: Membrane
messages: Type II secretion is composed of four main components: the outer membrane complex, the inner membrane complex, the cytoplasmic secretion ATPase and the periplasm-spanning pseudopilus.

365044:PNAP RS23250
gene id: 365044:PNAP_RS23250
uniprot id: A1VWC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone-like protein H-NS family.
messages: nucleoid

365044:PNAP RS17170
gene id: 365044:PNAP_RS17170
uniprot id: A1VSV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

365044:PNAP RS09285
gene id: 365044:PNAP_RS09285
uniprot id: A1VND6
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

365044:PNAP RS17980
gene id: 365044:PNAP_RS17980
uniprot id: A1VTC1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system and for the release of the potassium ions to the cytoplasm.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

365044:PNAP RS08810
gene id: 365044:PNAP_RS08810
uniprot id: A1VN42
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.

365044:PNAP RS06490
gene id: 365044:PNAP_RS06490
uniprot id: A1VLT1
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

365044:PNAP RS09395
gene id: 365044:PNAP_RS09395
uniprot id: A1VNF8
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

365044:PNAP RS07170
gene id: 365044:PNAP_RS07170
uniprot id: A1VM72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

365044:PNAP RS20805
gene id: 365044:PNAP_RS20805
uniprot id: A1VUY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family.
messages: Membrane

365044:PNAP RS05100
gene id: 365044:PNAP_RS05100
uniprot id: A1VL13
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

365044:PNAP RS06230
gene id: 365044:PNAP_RS06230
uniprot id: A1VLN1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. RhlE subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in ribosome assembly. Has RNA-dependent ATPase activity and unwinds double-stranded RNA.

365044:PNAP RS18595
gene id: 365044:PNAP_RS18595
uniprot id: A1VTN7
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

365044:PNAP RS20095
gene id: 365044:PNAP_RS20095
uniprot id: A1VUJ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
messages: Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
messages: Homodimer.

365044:PNAP RS12980
gene id: 365044:PNAP_RS12980
uniprot id: A1VQH2
names: Function
names: Similarity
messages: Belongs to the RlpA family.
messages: Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.

365044:PNAP RS15360
gene id: 365044:PNAP_RS15360
uniprot id: A1VRU2
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

365044:PNAP RS06580
gene id: 365044:PNAP_RS06580
uniprot id: A1VLU9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
messages: Cytoplasm
messages: Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity.

365044:PNAP RS17750
gene id: 365044:PNAP_RS17750
uniprot id: A1VT75
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Clade 'B2' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
messages: Cytoplasm
messages: Homodimer.
messages: Non-allosteric.

365044:PNAP RS16120
gene id: 365044:PNAP_RS16120
uniprot id: A1VSA1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

365044:PNAP RS15245
gene id: 365044:PNAP_RS15245
uniprot id: A1VRR9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

365044:PNAP RS07335
gene id: 365044:PNAP_RS07335
uniprot id: A1VMA5
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

365044:PNAP RS17420
gene id: 365044:PNAP_RS17420
uniprot id: A1VT08
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

365044:PNAP RS04230
gene id: 365044:PNAP_RS04230
uniprot id: A1VKJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

365044:PNAP RS14575
gene id: 365044:PNAP_RS14575
uniprot id: A1VRE1
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

365044:PNAP RS13140
gene id: 365044:PNAP_RS13140
uniprot id: A1VQK5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
messages: Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD).

365044:PNAP RS04055
gene id: 365044:PNAP_RS04055
uniprot id: A1VKF7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

365044:PNAP RS11520
gene id: 365044:PNAP_RS11520
uniprot id: A1VPN3
names: Subcellular Location Annotation
messages: Membrane

365044:PNAP RS01240
gene id: 365044:PNAP_RS01240
uniprot id: A1VIU9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase delta chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

365044:PNAP RS01130
gene id: 365044:PNAP_RS01130
uniprot id: A1VIS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

365044:PNAP RS08040
gene id: 365044:PNAP_RS08040
uniprot id: A1VMP6
names: Similarity
messages: Belongs to the bacterial solute-binding protein 1 family.

365044:PNAP RS02490
gene id: 365044:PNAP_RS02490
uniprot id: A1VJJ4
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

365044:PNAP RS03840
gene id: 365044:PNAP_RS03840
uniprot id: A1VKB5
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

365044:PNAP RS19945
gene id: 365044:PNAP_RS19945
uniprot id: A1VUG8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

365044:PNAP RS03300
gene id: 365044:PNAP_RS03300
uniprot id: A1VK07
names: Subcellular Location Annotation
messages: Membrane

365044:PNAP RS02465
gene id: 365044:PNAP_RS02465
uniprot id: A1VJI9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RlmJ family.
messages: Monomer.
messages: Specifically methylates the adenine in position 2030 of 23S rRNA.

365044:PNAP RS04750
gene id: 365044:PNAP_RS04750
uniprot id: A1VKU1
names: Similarity
messages: Belongs to the fabD family.

365044:PNAP RS04640
gene id: 365044:PNAP_RS04640
uniprot id: A1VKS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

365044:PNAP RS01705
gene id: 365044:PNAP_RS01705
uniprot id: A1VJ41
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

365044:PNAP RS11915
gene id: 365044:PNAP_RS11915
uniprot id: A1VPW1
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

365044:PNAP RS09830
gene id: 365044:PNAP_RS09830
uniprot id: A1VNP2
names: Similarity
messages: Belongs to the HupF/HypC family.

365044:PNAP RS09965
gene id: 365044:PNAP_RS09965
uniprot id: A1VNR9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.
messages: One is catalytic and the other provides a structural contribution.

365044:PNAP RS00910
gene id: 365044:PNAP_RS00910
uniprot id: A1VIN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell inner membrane
messages: Membrane

365044:PNAP RS09955
gene id: 365044:PNAP_RS09955
uniprot id: A1VNR7
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

365044:PNAP RS09900
gene id: 365044:PNAP_RS09900
uniprot id: A1VNQ6
names: Similarity
names: Subunit
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family.
messages: Heterodimer of a large and a small subunit.

365044:PNAP RS08915
gene id: 365044:PNAP_RS08915
uniprot id: A1VN63
names: Function
names: Subunit
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
messages: Homodimer. Part of the PDH complex, consisting of multiple copies of pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

365044:PNAP RS18430
gene id: 365044:PNAP_RS18430
uniprot id: A1VTK5
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

365044:PNAP RS11975
gene id: 365044:PNAP_RS11975
uniprot id: A1VPX3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PriB family.
messages: Binds single-stranded DNA at the primosome assembly site (PAS).
messages: Component of the preprimosomal complex composed of PriA, PriB, PriC, DnaB and DnaT. Upon transient interaction with DnaG it forms the primosome.

365044:PNAP RS01040
gene id: 365044:PNAP_RS01040
uniprot id: A1VIQ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

365044:PNAP RS19360
gene id: 365044:PNAP_RS19360
uniprot id: A1VU42
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

365044:PNAP RS17715
gene id: 365044:PNAP_RS17715
uniprot id: A1VT68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

365044:PNAP RS08585
gene id: 365044:PNAP_RS08585
uniprot id: A1VN03
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

365044:PNAP RS06225
gene id: 365044:PNAP_RS06225
uniprot id: A1VLN0
names: Similarity
messages: Belongs to the hemerythrin family.

365044:PNAP RS12390
gene id: 365044:PNAP_RS12390
uniprot id: Q3S4C6
names: Similarity
messages: Belongs to the extradiol ring-cleavage dioxygenase family.

365044:PNAP RS07600
gene id: 365044:PNAP_RS07600
uniprot id: A1VMF8
names: Subcellular Location Annotation
messages: Membrane

365044:PNAP RS17585
gene id: 365044:PNAP_RS17585
uniprot id: A1VT41
names: Subcellular Location Annotation
messages: Membrane

365044:PNAP RS22300
gene id: 365044:PNAP_RS22300
uniprot id: A1VVT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

365044:PNAP RS07125
gene id: 365044:PNAP_RS07125
uniprot id: A1VM63
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

365044:PNAP RS00125
gene id: 365044:PNAP_RS00125
uniprot id: A1VI71
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

365044:PNAP RS14230
gene id: 365044:PNAP_RS14230
uniprot id: A1VR71
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

365044:PNAP RS05385
gene id: 365044:PNAP_RS05385
uniprot id: A1VL69
names: Similarity
messages: Belongs to the UPF0234 family.

365044:PNAP RS18015
gene id: 365044:PNAP_RS18015
uniprot id: A1VTC7
names: Subcellular Location Annotation
messages: Membrane

365044:PNAP RS07705
gene id: 365044:PNAP_RS07705
uniprot id: A1VMH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic sulfate-binding protein family.
messages: Periplasm

365044:PNAP RS11445
gene id: 365044:PNAP_RS11445
uniprot id: A1VPL6
names: Function
names: Similarity
messages: Belongs to the heat shock protein 70 family.
messages: Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB.

365044:PNAP RS19015
gene id: 365044:PNAP_RS19015
uniprot id: A1VTX4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

365044:PNAP RS15170
gene id: 365044:PNAP_RS15170
uniprot id: A1VRQ4
names: Cofactor
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD.
messages: The heme is bound between the two transmembrane subunits.

365044:PNAP RS03315
gene id: 365044:PNAP_RS03315
uniprot id: A1VK10
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

365044:PNAP RS01075
gene id: 365044:PNAP_RS01075
uniprot id: A1VIR6
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

365044:PNAP RS10105
gene id: 365044:PNAP_RS10105
uniprot id: A1VNU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

365044:PNAP RS11935
gene id: 365044:PNAP_RS11935
uniprot id: A1VPW5
names: Similarity
messages: Belongs to the UPF0229 family.

365044:PNAP RS10005
gene id: 365044:PNAP_RS10005
uniprot id: A1VNS7
names: Similarity
messages: Belongs to the peptidase S66 family.

365044:PNAP RS08820
gene id: 365044:PNAP_RS08820
uniprot id: A1VN44
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

365044:PNAP RS03245
gene id: 365044:PNAP_RS03245
uniprot id: A1VJZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

365044:PNAP RS07810
gene id: 365044:PNAP_RS07810
uniprot id: A1VMK0
names: Similarity
messages: Belongs to the adrenodoxin/putidaredoxin family.

365044:PNAP RS07515
gene id: 365044:PNAP_RS07515
uniprot id: A1VME0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

365044:PNAP RS16985
gene id: 365044:PNAP_RS16985
uniprot id: A1VSR9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. MrdB/RodA subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell wall elongation.

365044:PNAP RS08885
gene id: 365044:PNAP_RS08885
uniprot id: A1VN57
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

365044:PNAP RS17875
gene id: 365044:PNAP_RS17875
uniprot id: A1VTA0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response.
messages: Belongs to the SrkA/RdoA protein kinase family.
messages: Cytoplasm
messages: Monomer.

365044:PNAP RS13300
gene id: 365044:PNAP_RS13300
uniprot id: A1VQN6
names: Similarity
messages: Belongs to the catalase family.

365044:PNAP RS09225
gene id: 365044:PNAP_RS09225
uniprot id: A1VNC5
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

365044:PNAP RS01030
gene id: 365044:PNAP_RS01030
uniprot id: A1VIQ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

365044:PNAP RS20515
gene id: 365044:PNAP_RS20515
uniprot id: A1VUS9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

365044:PNAP RS20635
gene id: 365044:PNAP_RS20635
uniprot id: A1VUV1
names: Similarity
messages: Belongs to the 4-hydroxy-2-oxovalerate aldolase family.

365044:PNAP RS18950
gene id: 365044:PNAP_RS18950
uniprot id: A1VTW0
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HPrK/P family.
messages: Both phosphorylation and phosphorolysis are carried out by the same active site and suggest a common mechanism for both reactions.
messages: Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr).
messages: Homohexamer.
messages: The Walker A ATP-binding motif also binds Pi and PPi.

365044:PNAP RS18920
gene id: 365044:PNAP_RS18920
uniprot id: A1VTV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

365044:PNAP RS13175
gene id: 365044:PNAP_RS13175
uniprot id: A1VQL2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ApbE family.
messages: Cell inner membrane
messages: Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.
messages: Magnesium. Can also use manganese.

365044:PNAP RS00170
gene id: 365044:PNAP_RS00170
uniprot id: A1VI80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0391 family.
messages: Cell membrane

365044:PNAP RS15385
gene id: 365044:PNAP_RS15385
uniprot id: A1VRU7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

365044:PNAP RS16825
gene id: 365044:PNAP_RS16825
uniprot id: A1VSN8
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

365044:PNAP RS04195
gene id: 365044:PNAP_RS04195
uniprot id: A1VKI3
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

365044:PNAP RS03155
gene id: 365044:PNAP_RS03155
uniprot id: A1VJX8
names: Subcellular Location Annotation
messages: Membrane

365044:PNAP RS16040
gene id: 365044:PNAP_RS16040
uniprot id: A1VS85
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

365044:PNAP RS10610
gene id: 365044:PNAP_RS10610
uniprot id: A1VP46
names: Similarity
messages: Belongs to the hemerythrin family.

365044:PNAP RS13885
gene id: 365044:PNAP_RS13885
uniprot id: A1VR04
names: Similarity
messages: Belongs to the glutamine synthetase family.

365044:PNAP RS18215
gene id: 365044:PNAP_RS18215
uniprot id: A1VIP8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

365044:PNAP RS19335
gene id: 365044:PNAP_RS19335
uniprot id: A1VU37
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.
messages: One is catalytic and the other provides a structural contribution.

365044:PNAP RS01670
gene id: 365044:PNAP_RS01670
uniprot id: A1VJ33
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

365044:PNAP RS14560
gene id: 365044:PNAP_RS14560
uniprot id: A1VRD8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

365044:PNAP RS01340
gene id: 365044:PNAP_RS01340
uniprot id: A1VIW8
names: Similarity
messages: Belongs to the UPF0102 family.

365044:PNAP RS01600
gene id: 365044:PNAP_RS01600
uniprot id: A1VJ20
names: Similarity
messages: Belongs to the Dps family.

365044:PNAP RS22285
gene id: 365044:PNAP_RS22285
uniprot id: A1VVT3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.
messages: Homotetramer.
messages: Uses inorganic polyphosphate (polyP) as a donor to convert GDP to GTP or ADP to ATP.

365044:PNAP RS24510
gene id: 365044:PNAP_RS24510
uniprot id: A1VX23
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

365044:PNAP RS13805
gene id: 365044:PNAP_RS13805
uniprot id: A1VQY8
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

365044:PNAP RS06840
gene id: 365044:PNAP_RS06840
uniprot id: A1VM05
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

365044:PNAP RS09410
gene id: 365044:PNAP_RS09410
uniprot id: A1VNG1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. HflK subfamily.
messages: HflC and HflK could encode or regulate a protease.
messages: HflC and HflK may interact to form a multimeric complex.
messages: Membrane

365044:PNAP RS03025
gene id: 365044:PNAP_RS03025
uniprot id: A1VJV1
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

365044:PNAP RS05370
gene id: 365044:PNAP_RS05370
uniprot id: A1VL66
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

365044:PNAP RS13785
gene id: 365044:PNAP_RS13785
uniprot id: A1VQY4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

365044:PNAP RS20875
gene id: 365044:PNAP_RS20875
uniprot id: A1VUZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VirD4/TraG family.
messages: Membrane

365044:PNAP RS15285
gene id: 365044:PNAP_RS15285
uniprot id: A1VRS7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 3 family. NagZ subfamily.
messages: Cytoplasm
messages: Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides.

365044:PNAP RS00355
gene id: 365044:PNAP_RS00355
uniprot id: A1VIB6
names: Function
names: Similarity
messages: Belongs to the ParB family.
messages: Involved in chromosome partition. Localize to both poles of the predivisional cell following completion of DNA replication. Binds to the DNA origin of replication.

365044:PNAP RS01680
gene id: 365044:PNAP_RS01680
uniprot id: A1VJ35
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell inner membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

365044:PNAP RS03725
gene id: 365044:PNAP_RS03725
uniprot id: A1VK93
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

365044:PNAP RS17255
gene id: 365044:PNAP_RS17255
uniprot id: A1VSX4
names: Similarity
messages: Belongs to the ABC transporter superfamily.

365044:PNAP RS01035
gene id: 365044:PNAP_RS01035
uniprot id: A1VIQ8
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

365044:PNAP RS09825
gene id: 365044:PNAP_RS09825
uniprot id: A1VNP1
names: Similarity
messages: Belongs to the HypD family.

365044:PNAP RS10345
gene id: 365044:PNAP_RS10345
uniprot id: A1VNZ2
names: Similarity
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.

365044:PNAP RS18805
gene id: 365044:PNAP_RS18805
uniprot id: A1VTT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Membrane

365044:PNAP RS08625
gene id: 365044:PNAP_RS08625
uniprot id: A1VN11
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

365044:PNAP RS08560
gene id: 365044:PNAP_RS08560
uniprot id: A1VMZ8
names: Subcellular Location Annotation
messages: Membrane

365044:PNAP RS18500
gene id: 365044:PNAP_RS18500
uniprot id: A1VTL9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

365044:PNAP RS11620
gene id: 365044:PNAP_RS11620
uniprot id: A1VPQ3
names: Similarity
messages: Belongs to the NifX/NifY family.

365044:PNAP RS07080
gene id: 365044:PNAP_RS07080
uniprot id: A1VM55
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

365044:PNAP RS19510
gene id: 365044:PNAP_RS19510
uniprot id: A1VU72
names: Similarity
messages: Belongs to the YoeB family.

365044:PNAP RS08845
gene id: 365044:PNAP_RS08845
uniprot id: A1VN49
names: Similarity
messages: Belongs to the skp family.

365044:PNAP RS08580
gene id: 365044:PNAP_RS08580
uniprot id: A1VN02
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

365044:PNAP RS12040
gene id: 365044:PNAP_RS12040
uniprot id: A1VPY5
names: Similarity
messages: Belongs to the CapA family.

365044:PNAP RS08655
gene id: 365044:PNAP_RS08655
uniprot id: A1VN17
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

365044:PNAP RS22365
gene id: 365044:PNAP_RS22365
uniprot id: A1VVU6
names: Similarity
messages: Belongs to the 6-phosphogluconate dehydrogenase family.

365044:PNAP RS07615
gene id: 365044:PNAP_RS07615
uniprot id: A1VMG1
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

365044:PNAP RS10570
gene id: 365044:PNAP_RS10570
uniprot id: A1VP37
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

365044:PNAP RS19430
gene id: 365044:PNAP_RS19430
uniprot id: A1VU55
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.

365044:PNAP RS08640
gene id: 365044:PNAP_RS08640
uniprot id: A1VN14
names: Similarity
messages: Belongs to the GARS family.

365044:PNAP RS20315
gene id: 365044:PNAP_RS20315
uniprot id: A1VUN9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptD family.
messages: Cell outer membrane
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptE and LptA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.

365044:PNAP RS04170
gene id: 365044:PNAP_RS04170
uniprot id: A1VKH8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.

365044:PNAP RS00375
gene id: 365044:PNAP_RS00375
uniprot id: A1VIC1
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

365044:PNAP RS01190
gene id: 365044:PNAP_RS01190
uniprot id: A1VIT9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

365044:PNAP RS13850
gene id: 365044:PNAP_RS13850
uniprot id: A1VQZ7
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

365044:PNAP RS07195
gene id: 365044:PNAP_RS07195
uniprot id: A1VM77
names: Function
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia.

365044:PNAP RS23670
gene id: 365044:PNAP_RS23670
uniprot id: A1VWK7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

365044:PNAP RS08180
gene id: 365044:PNAP_RS08180
uniprot id: A1VMS2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

365044:PNAP RS14950
gene id: 365044:PNAP_RS14950
uniprot id: A1VRL0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
messages: Homodimer.

365044:PNAP RS04095
gene id: 365044:PNAP_RS04095
uniprot id: A1VKG4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

365044:PNAP RS21005
gene id: 365044:PNAP_RS21005
uniprot id: A1VV29
names: Similarity
messages: Belongs to the GSP E family.

365044:PNAP RS17620
gene id: 365044:PNAP_RS17620
uniprot id: A1VT49
names: Subcellular Location Annotation
messages: Membrane

365044:PNAP RS11000
gene id: 365044:PNAP_RS11000
uniprot id: A1VPC5
names: Similarity
messages: Belongs to the thioredoxin family.

365044:PNAP RS07715
gene id: 365044:PNAP_RS07715
uniprot id: A1VMI1
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

365044:PNAP RS20845
gene id: 365044:PNAP_RS20845
uniprot id: A1VUZ2
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

365044:PNAP RS13125
gene id: 365044:PNAP_RS13125
uniprot id: A1VQK2
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

365044:PNAP RS19300
gene id: 365044:PNAP_RS19300
uniprot id: A1VU30
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.

365044:PNAP RS05850
gene id: 365044:PNAP_RS05850
uniprot id: A1VLF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

365044:PNAP RS12395
gene id: 365044:PNAP_RS12395
uniprot id: A1VQ58
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

365044:PNAP RS20255
gene id: 365044:PNAP_RS20255
uniprot id: A1VUM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

365044:PNAP RS01345
gene id: 365044:PNAP_RS01345
uniprot id: A1VIW9
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIS family. GmhA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
messages: Cytoplasm
messages: Homotetramer.
messages: The reaction produces a racemic mixture of D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate.

365044:PNAP RS03705
gene id: 365044:PNAP_RS03705
uniprot id: A1VK89
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

365044:PNAP RS09595
gene id: 365044:PNAP_RS09595
uniprot id: A1VNJ6
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

365044:PNAP RS19405
gene id: 365044:PNAP_RS19405
uniprot id: A1VU50
names: Similarity
messages: Belongs to the Smg family.

365044:PNAP RS04895
gene id: 365044:PNAP_RS04895
uniprot id: A1VKX0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

365044:PNAP RS09190
gene id: 365044:PNAP_RS09190
uniprot id: A1VNB8
names: Function
names: Similarity
messages: Belongs to the SELO family.
messages: Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).

365044:PNAP RS14120
gene id: 365044:PNAP_RS14120
uniprot id: A1VR51
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

365044:PNAP RS20445
gene id: 365044:PNAP_RS20445
uniprot id: A1VUR4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine.

365044:PNAP RS09620
gene id: 365044:PNAP_RS09620
uniprot id: A1VNK1
names: Similarity
messages: Belongs to the asparaginase 1 family.

365044:PNAP RS15235
gene id: 365044:PNAP_RS15235
uniprot id: A1VRR7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

365044:PNAP RS23820
gene id: 365044:PNAP_RS23820
uniprot id: A1VWN6
names: Function
names: Similarity
messages: Belongs to the transposase 11 family.
messages: Involved in the transposition of the insertion sequence IS5.

365044:PNAP RS13555
gene id: 365044:PNAP_RS13555
uniprot id: A1VQT8
names: Subcellular Location Annotation
messages: Membrane

365044:PNAP RS10405
gene id: 365044:PNAP_RS10405
uniprot id: A1VP04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

365044:PNAP RS05965
gene id: 365044:PNAP_RS05965
uniprot id: A1VLH7
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

365044:PNAP RS09060
gene id: 365044:PNAP_RS09060
uniprot id: A1VN92
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M20A family. DapE subfamily.
messages: Binds 2 Zn(2+) or Co(2+) ions per subunit.
messages: Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
messages: Homodimer.

365044:PNAP RS09935
gene id: 365044:PNAP_RS09935
uniprot id: A1VNR3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.

365044:PNAP RS14645
gene id: 365044:PNAP_RS14645
uniprot id: A1VRF5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon.

365044:PNAP RS03820
gene id: 365044:PNAP_RS03820
uniprot id: A1VKB1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ZapD family.
messages: Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity.
messages: Cytoplasm
messages: Interacts with FtsZ.

365044:PNAP RS03680
gene id: 365044:PNAP_RS03680
uniprot id: A1VK84
names: Subcellular Location Annotation
messages: Membrane

365044:PNAP RS18455
gene id: 365044:PNAP_RS18455
uniprot id: A1VTL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

365044:PNAP RS05450
gene id: 365044:PNAP_RS05450
uniprot id: A1VL82
names: Function
names: Similarity
names: Subunit
messages: Belongs to the trans-sulfuration enzymes family. MetZ subfamily.
messages: Catalyzes the formation of L-homocysteine from O-succinyl-L-homoserine (OSHS) and hydrogen sulfide.
messages: Homotetramer.

365044:PNAP RS07000
gene id: 365044:PNAP_RS07000
uniprot id: A1VM38
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

365044:PNAP RS17435
gene id: 365044:PNAP_RS17435
uniprot id: A1VT11
names: Subcellular Location Annotation
messages: Membrane

365044:PNAP RS11560
gene id: 365044:PNAP_RS11560
uniprot id: A1VPP1
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

365044:PNAP RS01390
gene id: 365044:PNAP_RS01390
uniprot id: A1VIX6
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

365044:PNAP RS01675
gene id: 365044:PNAP_RS01675
uniprot id: A1VJ34
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

365044:PNAP RS02825
gene id: 365044:PNAP_RS02825
uniprot id: A1VJR1
names: PTM
messages: Binds 1 heme group per subunit.

365044:PNAP RS03290
gene id: 365044:PNAP_RS03290
uniprot id: A1VK05
names: PTM
messages: Binds 2 heme c groups covalently per subunit.

365044:PNAP RS14805
gene id: 365044:PNAP_RS14805
uniprot id: A1VRI1
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

365044:PNAP RS00300
gene id: 365044:PNAP_RS00300
uniprot id: A1VIA5
names: Similarity
messages: Belongs to the histone deacetylase family.

365044:PNAP RS19930
gene id: 365044:PNAP_RS19930
uniprot id: A1VUG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

365044:PNAP RS01245
gene id: 365044:PNAP_RS01245
uniprot id: A1VIV0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

365044:PNAP RS11550
gene id: 365044:PNAP_RS11550
uniprot id: A1VPN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

365044:PNAP RS16105
gene id: 365044:PNAP_RS16105
uniprot id: A1VS98
names: Function
names: Similarity
messages: Belongs to the ribF family.
messages: Catalyzes the phosphorylation of riboflavin to FMN followed by the adenylation of FMN to FAD.

365044:PNAP RS10835
gene id: 365044:PNAP_RS10835
uniprot id: A1VP90
names: Function
names: Similarity
messages: Belongs to the CbiD family.
messages: Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.

365044:PNAP RS19860
gene id: 365044:PNAP_RS19860
uniprot id: A1VUF3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-(-)-3-hydroxybutyrate oligomer hydrolase family.
messages: Participates in the degradation of poly-3-hydroxybutyrate (PHB). It works downstream of poly(3-hydroxybutyrate) depolymerase, hydrolyzing D(-)-3-hydroxybutyrate oligomers of various length (3HB-oligomers) into 3HB-monomers.
messages: Secreted

365044:PNAP RS12100
gene id: 365044:PNAP_RS12100
uniprot id: A1VPZ7
names: Function
names: Similarity
messages: Belongs to the SsuD family.
messages: Catalyzes the desulfonation of aliphatic sulfonates.

365044:PNAP RS00985
gene id: 365044:PNAP_RS00985
uniprot id: A1VIP8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

365044:PNAP RS19250
gene id: 365044:PNAP_RS19250
uniprot id: A1VU20
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

365044:PNAP RS02580
gene id: 365044:PNAP_RS02580
uniprot id: A1VJL2
names: Subcellular Location Annotation
messages: Mitochondrion

365044:PNAP RS15495
gene id: 365044:PNAP_RS15495
uniprot id: A1VRW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

365044:PNAP RS13040
gene id: 365044:PNAP_RS13040
uniprot id: A1VQI5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

365044:PNAP RS07980
gene id: 365044:PNAP_RS07980
uniprot id: A1VMN4
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

365044:PNAP RS01230
gene id: 365044:PNAP_RS01230
uniprot id: A1VIU7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase C chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

365044:PNAP RS00315
gene id: 365044:PNAP_RS00315
uniprot id: A1VIA8
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

365044:PNAP RS16660
gene id: 365044:PNAP_RS16660
uniprot id: A1VSK4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.

365044:PNAP RS21240
gene id: 365044:PNAP_RS21240
uniprot id: A1VV77
names: Similarity
messages: Belongs to the AAA ATPase family.

365044:PNAP RS11665
gene id: 365044:PNAP_RS11665
uniprot id: A1VPR1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase A chain family.
messages: Cell inner membrane
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

365044:PNAP RS04320
gene id: 365044:PNAP_RS04320
uniprot id: A1VKK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

365044:PNAP RS08605
gene id: 365044:PNAP_RS08605
uniprot id: A1VN07
names: Similarity
messages: Belongs to the peptidase S11 family.

365044:PNAP RS19240
gene id: 365044:PNAP_RS19240
uniprot id: A1VU18
names: Similarity
messages: Belongs to the YjdM family.

365044:PNAP RS17235
gene id: 365044:PNAP_RS17235
uniprot id: A1VSX0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Homodimer.

365044:PNAP RS17060
gene id: 365044:PNAP_RS17060
uniprot id: A1VST6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell inner membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).

365044:PNAP RS07775
gene id: 365044:PNAP_RS07775
uniprot id: A1VMJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

365044:PNAP RS23755
gene id: 365044:PNAP_RS23755
uniprot id: A1VWM4
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

365044:PNAP RS17570
gene id: 365044:PNAP_RS17570
uniprot id: A1VT38
names: Subcellular Location Annotation
messages: Membrane

365044:PNAP RS08360
gene id: 365044:PNAP_RS08360
uniprot id: A1VMV7
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

365044:PNAP RS02110
gene id: 365044:PNAP_RS02110
uniprot id: A1VJB9
names: Function
names: Similarity
messages: Belongs to the transposase 11 family.
messages: Involved in the transposition of the insertion sequence IS5.

365044:PNAP RS07710
gene id: 365044:PNAP_RS07710
uniprot id: A1VMI0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import.
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

365044:PNAP RS14265
gene id: 365044:PNAP_RS14265
uniprot id: A1VR78
names: Cofactor
messages: Can also use Mn(2+) ion.

365044:PNAP RS10190
gene id: 365044:PNAP_RS10190
uniprot id: A1VNW4
names: Similarity
messages: Belongs to the PrpF family.

365044:PNAP RS05590
gene id: 365044:PNAP_RS05590
uniprot id: A1VLA4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

365044:PNAP RS01385
gene id: 365044:PNAP_RS01385
uniprot id: A1VIX5
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

365044:PNAP RS09305
gene id: 365044:PNAP_RS09305
uniprot id: A1VND9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

365044:PNAP RS08025
gene id: 365044:PNAP_RS08025
uniprot id: A1VMP3
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaved by autocatalysis into a large and a small subunit.
messages: This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide.

365044:PNAP RS11030
gene id: 365044:PNAP_RS11030
uniprot id: A1VPD1
names: Function
messages: This protein is a positive regulator for the phosphate regulon. Transcription of this operon is positively regulated by PhoB and PhoR when phosphate is limited.

365044:PNAP RS03515
gene id: 365044:PNAP_RS03515
uniprot id: A1VK51
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

365044:PNAP RS09140
gene id: 365044:PNAP_RS09140
uniprot id: A1VNA8
names: Similarity
messages: Belongs to the glucose-6-phosphate 1-epimerase family.

365044:PNAP RS03260
gene id: 365044:PNAP_RS03260
uniprot id: A1VJZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

365044:PNAP RS01060
gene id: 365044:PNAP_RS01060
uniprot id: A1VIR3
names: PTM
messages: Binds 1 heme group per subunit.

365044:PNAP RS11645
gene id: 365044:PNAP_RS11645
uniprot id: A1VPQ7
names: Function
names: Similarity
messages: Belongs to the ATPase gamma chain family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

365044:PNAP RS02185
gene id: 365044:PNAP_RS02185
uniprot id: A1VJD5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

365044:PNAP RS08015
gene id: 365044:PNAP_RS08015
uniprot id: A1VMP1
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

365044:PNAP RS16110
gene id: 365044:PNAP_RS16110
uniprot id: A1VS99
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

365044:PNAP RS05090
gene id: 365044:PNAP_RS05090
uniprot id: A1VL11
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

365044:PNAP RS22330
gene id: 365044:PNAP_RS22330
uniprot id: A1VVT9
names: Similarity
messages: Belongs to the asparagine synthetase family.

365044:PNAP RS15735
gene id: 365044:PNAP_RS15735
uniprot id: Q3S4B4
names: Similarity
messages: Belongs to the GST superfamily. Zeta family.

365044:PNAP RS09660
gene id: 365044:PNAP_RS09660
uniprot id: A1VNK9
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

365044:PNAP RS04615
gene id: 365044:PNAP_RS04615
uniprot id: A1VKR5
names: Similarity
messages: Belongs to the peptidase S41A family.

365044:PNAP RS01225
gene id: 365044:PNAP_RS01225
uniprot id: A1VIU6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase A chain family.
messages: Cell inner membrane
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

365044:PNAP RS07300
gene id: 365044:PNAP_RS07300
uniprot id: A1VM98
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

365044:PNAP RS15750
gene id: 365044:PNAP_RS15750
uniprot id: A1VS21
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

365044:PNAP RS04160
gene id: 365044:PNAP_RS04160
uniprot id: A1VKH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the formate dehydrogenase gamma subunit family.
messages: Membrane

365044:PNAP RS17080
gene id: 365044:PNAP_RS17080
uniprot id: A1VSU0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

365044:PNAP RS07885
gene id: 365044:PNAP_RS07885
uniprot id: A1VML6
names: Similarity
messages: Belongs to the NifZ family.

365044:PNAP RS18985
gene id: 365044:PNAP_RS18985
uniprot id: A1VTW7
names: Function
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

365044:PNAP RS15480
gene id: 365044:PNAP_RS15480
uniprot id: A1VRW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

365044:PNAP RS21075
gene id: 365044:PNAP_RS21075
uniprot id: A1VV43
names: Similarity
messages: Belongs to the TrbG/VirB9 family.

365044:PNAP RS14335
gene id: 365044:PNAP_RS14335
uniprot id: A1VR92
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

365044:PNAP RS17680
gene id: 365044:PNAP_RS17680
uniprot id: A1VT61
names: Similarity
messages: Belongs to the DEAD box helicase family.

365044:PNAP RS09440
gene id: 365044:PNAP_RS09440
uniprot id: A1VNG7
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

365044:PNAP RS09765
gene id: 365044:PNAP_RS09765
uniprot id: A1VNM9
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

365044:PNAP RS01140
gene id: 365044:PNAP_RS01140
uniprot id: A1VIS9
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family. Sucrose phosphorylase subfamily.

365044:PNAP RS03000
gene id: 365044:PNAP_RS03000
uniprot id: A1VJU6
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

365044:PNAP RS23410
gene id: 365044:PNAP_RS23410
uniprot id: A1VWF4
names: Similarity
messages: Belongs to the HipA Ser/Thr kinase family.

365044:PNAP RS19260
gene id: 365044:PNAP_RS19260
uniprot id: A1VU22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family.
messages: Membrane

365044:PNAP RS07310
gene id: 365044:PNAP_RS07310
uniprot id: A1VMA0
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

365044:PNAP RS18735
gene id: 365044:PNAP_RS18735
uniprot id: A1VTR6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Cell inner membrane
messages: Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate from the periplasm across the membrane.

365044:PNAP RS13035
gene id: 365044:PNAP_RS13035
uniprot id: A1VQI4
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

365044:PNAP RS13130
gene id: 365044:PNAP_RS13130
uniprot id: A1VQK3
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

365044:PNAP RS10890
gene id: 365044:PNAP_RS10890
uniprot id: A1VPA1
names: Subcellular Location Annotation
messages: Membrane

365044:PNAP RS25045
gene id: 365044:PNAP_RS25045
uniprot id: A1VRI7
names: Similarity
messages: Belongs to the MipA/OmpV family.

365044:PNAP RS10755
gene id: 365044:PNAP_RS10755
uniprot id: A1VP74
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

365044:PNAP RS15190
gene id: 365044:PNAP_RS15190
uniprot id: A1VRQ8
names: Similarity
messages: Belongs to the citrate synthase family.

365044:PNAP RS17575
gene id: 365044:PNAP_RS17575
uniprot id: A1VT39
names: Subcellular Location Annotation
messages: Membrane

365044:PNAP RS17810
gene id: 365044:PNAP_RS17810
uniprot id: A1VT87
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

365044:PNAP RS03755
gene id: 365044:PNAP_RS03755
uniprot id: A1VK98
names: Similarity
messages: Belongs to the GSP N family.

365044:PNAP RS02340
gene id: 365044:PNAP_RS02340
uniprot id: A1VJG6
names: Similarity
messages: Belongs to the DinB family.

365044:PNAP RS04075
gene id: 365044:PNAP_RS04075
uniprot id: A1VKG0
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

365044:PNAP RS09940
gene id: 365044:PNAP_RS09940
uniprot id: A1VNR4
names: Similarity
messages: Belongs to the phosphoribulokinase family.

365044:PNAP RS07150
gene id: 365044:PNAP_RS07150
uniprot id: A1VM68
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

365044:PNAP RS02710
gene id: 365044:PNAP_RS02710
uniprot id: A1VJN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

365044:PNAP RS04630
gene id: 365044:PNAP_RS04630
uniprot id: A1VKR8
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.

365044:PNAP RS10855
gene id: 365044:PNAP_RS10855
uniprot id: A1VP94
names: Subcellular Location Annotation
messages: Membrane

365044:PNAP RS15255
gene id: 365044:PNAP_RS15255
uniprot id: A1VRS1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

365044:PNAP RS14685
gene id: 365044:PNAP_RS14685
uniprot id: A1VRG3
names: Subunit
messages: Homodimer.

365044:PNAP RS17335
gene id: 365044:PNAP_RS17335
uniprot id: A1VSZ0
names: Subcellular Location Annotation
messages: Membrane

365044:PNAP RS09375
gene id: 365044:PNAP_RS09375
uniprot id: A1VNF4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

365044:PNAP RS07175
gene id: 365044:PNAP_RS07175
uniprot id: A1VM73
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

365044:PNAP RS09865
gene id: 365044:PNAP_RS09865
uniprot id: A1VNP9
names: Similarity
messages: Belongs to the HupH/HyaF family.

365044:PNAP RS18470
gene id: 365044:PNAP_RS18470
uniprot id: A1VTL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial glucokinase family.
messages: Cytoplasm

365044:PNAP RS17410
gene id: 365044:PNAP_RS17410
uniprot id: A1VT06
names: Subcellular Location Annotation
messages: Membrane

365044:PNAP RS15025
gene id: 365044:PNAP_RS15025
uniprot id: A1VRM5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell inner membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

365044:PNAP RS09415
gene id: 365044:PNAP_RS09415
uniprot id: A1VNG2
names: Function
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflC subfamily.
messages: HflC and HflK could regulate a protease.

365044:PNAP RS15970
gene id: 365044:PNAP_RS15970
uniprot id: A1VS71
names: Subcellular Location Annotation
messages: Membrane

365044:PNAP RS05940
gene id: 365044:PNAP_RS05940
uniprot id: A1VLH3
names: Activity Regulation
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.

365044:PNAP RS16850
gene id: 365044:PNAP_RS16850
uniprot id: A1VSP2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

365044:PNAP RS04975
gene id: 365044:PNAP_RS04975
uniprot id: A1VKY7
names: Subcellular Location Annotation
messages: Membrane

365044:PNAP RS06010
gene id: 365044:PNAP_RS06010
uniprot id: A1VLI7
names: Similarity
messages: Belongs to the transglycosylase Slt family.

365044:PNAP RS05215
gene id: 365044:PNAP_RS05215
uniprot id: A1VL36
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia.

365044:PNAP RS24560
gene id: 365044:PNAP_RS24560
uniprot id: A1VX33
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

365044:PNAP RS07995
gene id: 365044:PNAP_RS07995
uniprot id: A1VMN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

365044:PNAP RS10505
gene id: 365044:PNAP_RS10505
uniprot id: A1VP24
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

365044:PNAP RS10100
gene id: 365044:PNAP_RS10100
uniprot id: A1VNU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

365044:PNAP RS01605
gene id: 365044:PNAP_RS01605
uniprot id: A1VJ21
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family.
messages: Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
messages: Cell inner membrane

365044:PNAP RS10205
gene id: 365044:PNAP_RS10205
uniprot id: A1VNW7
names: Similarity
messages: Belongs to the ModE family.

365044:PNAP RS10840
gene id: 365044:PNAP_RS10840
uniprot id: A1VP91
names: Similarity
messages: Belongs to the CobH/CbiC family.

365044:PNAP RS11860
gene id: 365044:PNAP_RS11860
uniprot id: A1VPV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

365044:PNAP RS11435
gene id: 365044:PNAP_RS11435
uniprot id: A1VPL4
names: Function
names: Subunit
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease.

365044:PNAP RS03270
gene id: 365044:PNAP_RS03270
uniprot id: A1VK01
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

365044:PNAP RS16940
gene id: 365044:PNAP_RS16940
uniprot id: A1VSR0
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

365044:PNAP RS09385
gene id: 365044:PNAP_RS09385
uniprot id: A1VNF6
names: Similarity
messages: Belongs to the YfgM family.

365044:PNAP RS07820
gene id: 365044:PNAP_RS07820
uniprot id: A1VMK2
names: Similarity
messages: Belongs to the HesB/IscA family.

365044:PNAP RS07785
gene id: 365044:PNAP_RS07785
uniprot id: A1VMJ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

365044:PNAP RS13830
gene id: 365044:PNAP_RS13830
uniprot id: A1VQZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0761 family.
messages: Cell inner membrane
messages: Membrane

365044:PNAP RS02460
gene id: 365044:PNAP_RS02460
uniprot id: A1VJI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

365044:PNAP RS12420
gene id: 365044:PNAP_RS12420
uniprot id: Q3S4D2
names: Similarity
messages: Belongs to the bacterial ring-hydroxylating dioxygenase beta subunit family.

365044:PNAP RS15345
gene id: 365044:PNAP_RS15345
uniprot id: A1VRT9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

365044:PNAP RS17515
gene id: 365044:PNAP_RS17515
uniprot id: A1VT27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

365044:PNAP RS19700
gene id: 365044:PNAP_RS19700
uniprot id: A1VUB9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

365044:PNAP RS16075
gene id: 365044:PNAP_RS16075
uniprot id: A1VS92
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

365044:PNAP RS16680
gene id: 365044:PNAP_RS16680
uniprot id: A1VSK8
names: Similarity
messages: Belongs to the UPF0758 family.

365044:PNAP RS14380
gene id: 365044:PNAP_RS14380
uniprot id: A1VRA1
names: Caution
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

365044:PNAP RS13020
gene id: 365044:PNAP_RS13020
uniprot id: A1VQI1
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

365044:PNAP RS07765
gene id: 365044:PNAP_RS07765
uniprot id: A1VMJ1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

365044:PNAP RS19070
gene id: 365044:PNAP_RS19070
uniprot id: A1VTY5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm

365044:PNAP RS04405
gene id: 365044:PNAP_RS04405
uniprot id: A1VKM5
names: Subcellular Location Annotation
messages: Membrane

365044:PNAP RS15185
gene id: 365044:PNAP_RS15185
uniprot id: A1VRQ7
names: Similarity
messages: Belongs to the SdhE FAD assembly factor family.

365044:PNAP RS07675
gene id: 365044:PNAP_RS07675
uniprot id: A1VMH3
names: Subcellular Location Annotation
messages: Membrane

365044:PNAP RS15155
gene id: 365044:PNAP_RS15155
uniprot id: A1VRQ1
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 2 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

365044:PNAP RS00835
gene id: 365044:PNAP_RS00835
uniprot id: A1VIL8
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

365044:PNAP RS03535
gene id: 365044:PNAP_RS03535
uniprot id: A1VK55
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b family.
messages: Binds 2 heme groups non-covalently.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

365044:PNAP RS11035
gene id: 365044:PNAP_RS11035
uniprot id: A1VPD2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

365044:PNAP RS20500
gene id: 365044:PNAP_RS20500
uniprot id: A1VUS5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell inner membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

365044:PNAP RS00060
gene id: 365044:PNAP_RS00060
uniprot id: A1VI57
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MinC family.
messages: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.
messages: Interacts with MinD and FtsZ.

365044:PNAP RS09150
gene id: 365044:PNAP_RS09150
uniprot id: A1VNB0
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

365044:PNAP RS01235
gene id: 365044:PNAP_RS01235
uniprot id: A1VIU8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell inner membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.

365044:PNAP RS17440
gene id: 365044:PNAP_RS17440
uniprot id: A1VT12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone-like protein H-NS family.
messages: nucleoid

365044:PNAP RS19140
gene id: 365044:PNAP_RS19140
uniprot id: A1VTZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

365044:PNAP RS05955
gene id: 365044:PNAP_RS05955
uniprot id: A1VLH5
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

365044:PNAP RS01665
gene id: 365044:PNAP_RS01665
uniprot id: A1VJ32
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

365044:PNAP RS17090
gene id: 365044:PNAP_RS17090
uniprot id: A1VSU2
names: Function
names: Similarity
messages: Belongs to the transpeptidase family. FtsI subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall at the division septum.

365044:PNAP RS15835
gene id: 365044:PNAP_RS15835
uniprot id: A1VS38
names: Subcellular Location Annotation
messages: Membrane

365044:PNAP RS00690
gene id: 365044:PNAP_RS00690
uniprot id: A1VII6
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

365044:PNAP RS12130
gene id: 365044:PNAP_RS12130
uniprot id: A1VQ03
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Catalyzes the last two steps in the biosynthesis of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the DAO family.
messages: In the N-terminal section; belongs to the methyltransferase superfamily. tRNA (mnm(5)s(2)U34)-methyltransferase family.

365044:PNAP RS18415
gene id: 365044:PNAP_RS18415
uniprot id: A1VTK2
names: Function
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. S-2-haloalkanoic acid dehalogenase family.
messages: Catalyzes the hydrolytic dehalogenation of small (S)-2-haloalkanoic acids to yield the corresponding (R)-2-hydroxyalkanoic acids.

365044:PNAP RS13305
gene id: 365044:PNAP_RS13305
uniprot id: A1VQN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

365044:PNAP RS07835
gene id: 365044:PNAP_RS07835
uniprot id: A1VMK5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
messages: Cytoplasm
messages: Homodimer. Forms a heterotetramer with IscU, interacts with other sulfur acceptors.
messages: Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.

365044:PNAP RS09835
gene id: 365044:PNAP_RS09835
uniprot id: A1VNP3
names: Similarity
messages: Belongs to the carbamoyltransferase HypF family.

365044:PNAP RS15740
gene id: 365044:PNAP_RS15740
uniprot id: A1VS18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

365044:PNAP RS20375
gene id: 365044:PNAP_RS20375
uniprot id: A1VUQ1
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The autoendoproteolytic cleavage occurs by a canonical serine protease mechanism, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. During this reaction, the Ser that is part of the protease active site of the proenzyme becomes the pyruvoyl prosthetic group, which constitutes an essential element of the active site of the mature decarboxylase.

365044:PNAP RS02660
gene id: 365044:PNAP_RS02660
uniprot id: A1VJM8
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

365044:PNAP RS14385
gene id: 365044:PNAP_RS14385
uniprot id: A1VRA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0114 family.
messages: Cell membrane
messages: Membrane

365044:PNAP RS05650
gene id: 365044:PNAP_RS05650
uniprot id: A1VLB6
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

365044:PNAP RS05125
gene id: 365044:PNAP_RS05125
uniprot id: A1VL18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

365044:PNAP RS09645
gene id: 365044:PNAP_RS09645
uniprot id: A1VNK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

365044:PNAP RS23720
gene id: 365044:PNAP_RS23720
uniprot id: A1VWL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

365044:PNAP RS05440
gene id: 365044:PNAP_RS05440
uniprot id: A1VL80
names: Subcellular Location Annotation
messages: Membrane

365044:PNAP RS07625
gene id: 365044:PNAP_RS07625
uniprot id: A1VMG3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

365044:PNAP RS25430
gene id: 365044:PNAP_RS25430
uniprot id: A1VJ36
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

365044:PNAP RS03910
gene id: 365044:PNAP_RS03910
uniprot id: A1VKC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

365044:PNAP RS15180
gene id: 365044:PNAP_RS15180
uniprot id: A1VRQ6
names: Cofactor
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.

365044:PNAP RS17770
gene id: 365044:PNAP_RS17770
uniprot id: A1VT79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

365044:PNAP RS18295
gene id: 365044:PNAP_RS18295
uniprot id: A1VTH8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

365044:PNAP RS23680
gene id: 365044:PNAP_RS23680
uniprot id: A1VWK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

365044:PNAP RS07340
gene id: 365044:PNAP_RS07340
uniprot id: A1VMA6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-to-5' exoribonuclease specific for small oligoribonucleotides.
messages: Belongs to the oligoribonuclease family.
messages: Cytoplasm

365044:PNAP RS10220
gene id: 365044:PNAP_RS10220
uniprot id: A1VNX0
names: Similarity
messages: Belongs to the NadC/ModD family.

365044:PNAP RS06180
gene id: 365044:PNAP_RS06180
uniprot id: A1VLM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

365044:PNAP RS05200
gene id: 365044:PNAP_RS05200
uniprot id: A1VL33
names: Similarity
messages: Belongs to the BMP lipoprotein family.

365044:PNAP RS16255
gene id: 365044:PNAP_RS16255
uniprot id: A1VSC8
names: Similarity
messages: Belongs to the RecJ family.

365044:PNAP RS14290
gene id: 365044:PNAP_RS14290
uniprot id: A1VR83
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
messages: Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD).

365044:PNAP RS08035
gene id: 365044:PNAP_RS08035
uniprot id: A1VMP5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

365044:PNAP RS12790
gene id: 365044:PNAP_RS12790
uniprot id: A1VQD4
names: Cofactor
messages: Binds 1 Fe(2+) ion per subunit.

365044:PNAP RS15575
gene id: 365044:PNAP_RS15575
uniprot id: A1VRY6
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

365044:PNAP RS17050
gene id: 365044:PNAP_RS17050
uniprot id: A1VST4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

365044:PNAP RS16090
gene id: 365044:PNAP_RS16090
uniprot id: A1VS95
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

365044:PNAP RS01015
gene id: 365044:PNAP_RS01015
uniprot id: A1VIQ4
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

365044:PNAP RS00230
gene id: 365044:PNAP_RS00230
uniprot id: A1VI92
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

365044:PNAP RS03145
gene id: 365044:PNAP_RS03145
uniprot id: A1VJX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

365044:PNAP RS16045
gene id: 365044:PNAP_RS16045
uniprot id: A1VS86
names: Subcellular Location Annotation
messages: Membrane

365044:PNAP RS03585
gene id: 365044:PNAP_RS03585
uniprot id: A1VK64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

365044:PNAP RS03875
gene id: 365044:PNAP_RS03875
uniprot id: A1VKC2
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).

365044:PNAP RS14780
gene id: 365044:PNAP_RS14780
uniprot id: A1VRH7
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

365044:PNAP RS00760
gene id: 365044:PNAP_RS00760
uniprot id: A1VIK0
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

365044:PNAP RS06615
gene id: 365044:PNAP_RS06615
uniprot id: A1VLV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane OOP (TC 1.B.6) superfamily.
messages: Cell outer membrane
messages: Membrane

365044:PNAP RS18450
gene id: 365044:PNAP_RS18450
uniprot id: A1VTK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

365044:PNAP RS14460
gene id: 365044:PNAP_RS14460
uniprot id: A1VRB6
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

365044:PNAP RS19495
gene id: 365044:PNAP_RS19495
uniprot id: A1VU69
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

365044:PNAP RS09465
gene id: 365044:PNAP_RS09465
uniprot id: A1VNH2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. RlmB subfamily.
messages: Cytoplasm
messages: Specifically methylates the ribose of guanosine 2251 in 23S rRNA.

365044:PNAP RS16005
gene id: 365044:PNAP_RS16005
uniprot id: A1VS78
names: Subcellular Location Annotation
messages: Membrane

365044:PNAP RS10580
gene id: 365044:PNAP_RS10580
uniprot id: A1VP39
names: Subcellular Location Annotation
messages: Membrane

365044:PNAP RS17015
gene id: 365044:PNAP_RS17015
uniprot id: A1VSS6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).

365044:PNAP RS05060
gene id: 365044:PNAP_RS05060
uniprot id: A1VL05
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.

365044:PNAP RS24465
gene id: 365044:PNAP_RS24465
uniprot id: A1VX13
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

365044:PNAP RS06755
gene id: 365044:PNAP_RS06755
uniprot id: A1VLY8
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

365044:PNAP RS18325
gene id: 365044:PNAP_RS18325
uniprot id: A1VTI4
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG).

365044:PNAP RS00990
gene id: 365044:PNAP_RS00990
uniprot id: A1VIP9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

365044:PNAP RS19320
gene id: 365044:PNAP_RS19320
uniprot id: A1VU34
names: Similarity
messages: Belongs to the peptidase C56 family.

365044:PNAP RS10880
gene id: 365044:PNAP_RS10880
uniprot id: A1VP99
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

365044:PNAP RS18925
gene id: 365044:PNAP_RS18925
uniprot id: A1VTV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

365044:PNAP RS00650
gene id: 365044:PNAP_RS00650
uniprot id: A1VIH8
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

365044:PNAP RS14920
gene id: 365044:PNAP_RS14920
uniprot id: A1VRK4
names: Subcellular Location Annotation
messages: Membrane

365044:PNAP RS09120
gene id: 365044:PNAP_RS09120
uniprot id: A1VNA4
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

365044:PNAP RS10670
gene id: 365044:PNAP_RS10670
uniprot id: A1VP58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

365044:PNAP RS07320
gene id: 365044:PNAP_RS07320
uniprot id: A1VMA2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

365044:PNAP RS18775
gene id: 365044:PNAP_RS18775
uniprot id: A1VTS4
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

365044:PNAP RS18580
gene id: 365044:PNAP_RS18580
uniprot id: A1VTN4
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

365044:PNAP RS04525
gene id: 365044:PNAP_RS04525
uniprot id: A1VKP8
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

365044:PNAP RS07520
gene id: 365044:PNAP_RS07520
uniprot id: A1VME1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the selenophosphate synthase 1 family. Class I subfamily.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Homodimer.
messages: Synthesizes selenophosphate from selenide and ATP.

365044:PNAP RS13965
gene id: 365044:PNAP_RS13965
uniprot id: A1VR20
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS1 family.
messages: Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.

365044:PNAP RS15530
gene id: 365044:PNAP_RS15530
uniprot id: A1VRX7
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

365044:PNAP RS09695
gene id: 365044:PNAP_RS09695
uniprot id: A1VNL6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK.

365044:PNAP RS15765
gene id: 365044:PNAP_RS15765
uniprot id: A1VS24
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

365044:PNAP RS02775
gene id: 365044:PNAP_RS02775
uniprot id: A1VJQ0
names: Similarity
messages: Belongs to the SsuE family.

365044:PNAP RS14135
gene id: 365044:PNAP_RS14135
uniprot id: A1VR54
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

365044:PNAP RS15230
gene id: 365044:PNAP_RS15230
uniprot id: A1VRR6
names: Similarity
messages: Belongs to the TrpF family.

365044:PNAP RS03660
gene id: 365044:PNAP_RS03660
uniprot id: A1VK80
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

365044:PNAP RS11285
gene id: 365044:PNAP_RS11285
uniprot id: A1VPI3
names: Similarity
messages: Belongs to the peptidase S14 family.

365044:PNAP RS14410
gene id: 365044:PNAP_RS14410
uniprot id: A1VRA7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

365044:PNAP RS10090
gene id: 365044:PNAP_RS10090
uniprot id: A1VNU4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

365044:PNAP RS17125
gene id: 365044:PNAP_RS17125
uniprot id: A1VSU8
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

365044:PNAP RS16060
gene id: 365044:PNAP_RS16060
uniprot id: A1VS89
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

365044:PNAP RS00945
gene id: 365044:PNAP_RS00945
uniprot id: A1VIP0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HemJ family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Catalyzes the oxidation of protoporphyrinogen IX to protoporphyrin IX.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

365044:PNAP RS00850
gene id: 365044:PNAP_RS00850
uniprot id: A1VIM1
names: Function
names: Similarity
messages: Belongs to the MreC family.
messages: Involved in formation and maintenance of cell shape.

365044:PNAP RS03675
gene id: 365044:PNAP_RS03675
uniprot id: A1VK83
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

365044:PNAP RS00240
gene id: 365044:PNAP_RS00240
uniprot id: A1VI94
names: Similarity
messages: Belongs to the gluconokinase GntK/GntV family.

365044:PNAP RS00330
gene id: 365044:PNAP_RS00330
uniprot id: A1VIB1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

365044:PNAP RS05165
gene id: 365044:PNAP_RS05165
uniprot id: A1VL26
names: Subcellular Location Annotation
messages: Membrane

365044:PNAP RS13110
gene id: 365044:PNAP_RS13110
uniprot id: A1VQJ9
names: Subcellular Location Annotation
messages: Membrane

365044:PNAP RS13980
gene id: 365044:PNAP_RS13980
uniprot id: A1VR23
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LapB family.
messages: Cell inner membrane
messages: Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane.

365044:PNAP RS02650
gene id: 365044:PNAP_RS02650
uniprot id: A1VJM6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.

365044:PNAP RS03060
gene id: 365044:PNAP_RS03060
uniprot id: A1VJV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

365044:PNAP RS11455
gene id: 365044:PNAP_RS11455
uniprot id: A1VPL8
names: Similarity
messages: Belongs to the HesB/IscA family.

365044:PNAP RS03525
gene id: 365044:PNAP_RS03525
uniprot id: A1VK53
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell inner membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.

365044:PNAP RS04470
gene id: 365044:PNAP_RS04470
uniprot id: A1VKN8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

365044:PNAP RS05810
gene id: 365044:PNAP_RS05810
uniprot id: A1VLE8
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

365044:PNAP RS14585
gene id: 365044:PNAP_RS14585
uniprot id: A1VRE3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbB/TolQ family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

365044:PNAP RS13485
gene id: 365044:PNAP_RS13485
uniprot id: A1VQS4
names: Function
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase family.
messages: CoA transferase having broad substrate specificity for short-chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons.

365044:PNAP RS00935
gene id: 365044:PNAP_RS00935
uniprot id: A1VIN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

365044:PNAP RS01470
gene id: 365044:PNAP_RS01470
uniprot id: A1VIZ2
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

365044:PNAP RS18550
gene id: 365044:PNAP_RS18550
uniprot id: A1VTM8
names: Function
names: Similarity
messages: Belongs to the sigma-54 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

365044:PNAP RS11115
gene id: 365044:PNAP_RS11115
uniprot id: A1VPE8
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

365044:PNAP RS06380
gene id: 365044:PNAP_RS06380
uniprot id: A1VLR1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.
messages: Homotetramer.
messages: Uses inorganic polyphosphate (polyP) as a donor to convert GDP to GTP or ADP to ATP.

365044:PNAP RS08595
gene id: 365044:PNAP_RS08595
uniprot id: A1VN05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

365044:PNAP RS01175
gene id: 365044:PNAP_RS01175
uniprot id: A1VIT6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

365044:PNAP RS14590
gene id: 365044:PNAP_RS14590
uniprot id: A1VRE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

365044:PNAP RS09800
gene id: 365044:PNAP_RS09800
uniprot id: A1VNN6
names: Similarity
names: Subunit
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family.
messages: Heterodimer of a large and a small subunit.

365044:PNAP RS16315
gene id: 365044:PNAP_RS16315
uniprot id: A1VSE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

365044:PNAP RS07020
gene id: 365044:PNAP_RS07020
uniprot id: A1VM42
names: Subcellular Location Annotation
messages: Membrane

365044:PNAP RS10410
gene id: 365044:PNAP_RS10410
uniprot id: A1VP05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

365044:PNAP RS12630
gene id: 365044:PNAP_RS12630
uniprot id: A1VQA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VirD4/TraG family.
messages: Membrane

365044:PNAP RS03710
gene id: 365044:PNAP_RS03710
uniprot id: A1VK90
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

365044:PNAP RS08155
gene id: 365044:PNAP_RS08155
uniprot id: A1VMR9
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

365044:PNAP RS02520
gene id: 365044:PNAP_RS02520
uniprot id: A1VJK0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

365044:PNAP RS06285
gene id: 365044:PNAP_RS06285
uniprot id: A1VLP2
names: Subcellular Location Annotation
messages: Membrane

365044:PNAP RS03530
gene id: 365044:PNAP_RS03530
uniprot id: A1VK54
names: Cofactor
names: Function
names: Miscellaneous
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The Rieske protein is a high potential 2Fe-2S protein.
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

365044:PNAP RS06315
gene id: 365044:PNAP_RS06315
uniprot id: A1VLP8
names: Subcellular Location Annotation
messages: Periplasm

365044:PNAP RS23675
gene id: 365044:PNAP_RS23675
uniprot id: A1VWK8
names: Similarity
messages: Belongs to the serine/threonine dehydratase family. DsdA subfamily.

365044:PNAP RS19490
gene id: 365044:PNAP_RS19490
uniprot id: A1VU68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

365044:PNAP RS16445
gene id: 365044:PNAP_RS16445
uniprot id: A1VSG6
names: Similarity
messages: Belongs to the glycosyl hydrolase 24 family.

365044:PNAP RS05540
gene id: 365044:PNAP_RS05540
uniprot id: A1VL95
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.

365044:PNAP RS11165
gene id: 365044:PNAP_RS11165
uniprot id: A1VPF8
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

365044:PNAP RS00055
gene id: 365044:PNAP_RS00055
uniprot id: A1VI56
names: Function
names: Similarity
names: Subunit
messages: ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.
messages: Belongs to the ParA family. MinD subfamily.
messages: Interacts with MinC and FtsZ.

365044:PNAP RS03305
gene id: 365044:PNAP_RS03305
uniprot id: A1VK08
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MsrP family.
messages: Binds 1 Mo-molybdopterin (Mo-MPT) cofactor per subunit.
messages: Heterodimer of a catalytic subunit (MsrP) and a heme-binding subunit (MsrQ).
messages: Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide.
messages: Periplasm
messages: Predicted to be exported by the Tat system. The position of the signal peptide cleavage has not been experimentally proven.

365044:PNAP RS02680
gene id: 365044:PNAP_RS02680
uniprot id: A1VJN1
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

365044:PNAP RS16945
gene id: 365044:PNAP_RS16945
uniprot id: A1VSR1
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

365044:PNAP RS24385
gene id: 365044:PNAP_RS24385
uniprot id: A1VWZ5
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

365044:PNAP RS20685
gene id: 365044:PNAP_RS20685
uniprot id: A1VUW1
names: Similarity
messages: Belongs to the bacterial ring-hydroxylating dioxygenase alpha subunit family.

365044:PNAP RS15585
gene id: 365044:PNAP_RS15585
uniprot id: A1VRY8
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

365044:PNAP RS08505
gene id: 365044:PNAP_RS08505
uniprot id: A1VMY7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

365044:PNAP RS07970
gene id: 365044:PNAP_RS07970
uniprot id: A1VMN2
names: Similarity
messages: Belongs to the DapA family.

365044:PNAP RS14465
gene id: 365044:PNAP_RS14465
uniprot id: A1VRB7
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

365044:PNAP RS05180
gene id: 365044:PNAP_RS05180
uniprot id: A1VL29
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenine deaminase type 2 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism.

365044:PNAP RS16080
gene id: 365044:PNAP_RS16080
uniprot id: A1VS93
names: Similarity
messages: Belongs to the UPF0502 family.

365044:PNAP RS01620
gene id: 365044:PNAP_RS01620
uniprot id: A1VJ23
names: Activity Regulation
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.

365044:PNAP RS15880
gene id: 365044:PNAP_RS15880
uniprot id: A1VS46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

365044:PNAP RS01585
gene id: 365044:PNAP_RS01585
uniprot id: A1VJ16
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

365044:PNAP RS15815
gene id: 365044:PNAP_RS15815
uniprot id: A1VS34
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family. QueF type 2 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm
messages: Homodimer.

365044:PNAP RS11440
gene id: 365044:PNAP_RS11440
uniprot id: A1VPL5
names: Similarity
messages: Belongs to the adrenodoxin/putidaredoxin family.

365044:PNAP RS05085
gene id: 365044:PNAP_RS05085
uniprot id: A1VL10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

365044:PNAP RS24915
gene id: 365044:PNAP_RS24915
uniprot id: A1VMX0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

365044:PNAP RS07595
gene id: 365044:PNAP_RS07595
uniprot id: A1VMF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

365044:PNAP RS09720
gene id: 365044:PNAP_RS09720
uniprot id: A1VNM1
names: Function
names: Similarity
messages: Belongs to the TrhO family.
messages: Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.

365044:PNAP RS09820
gene id: 365044:PNAP_RS09820
uniprot id: A1VNP0
names: Similarity
messages: Belongs to the HypE family.

365044:PNAP RS15365
gene id: 365044:PNAP_RS15365
uniprot id: A1VRU3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

365044:PNAP RS09110
gene id: 365044:PNAP_RS09110
uniprot id: A1VNA2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

365044:PNAP RS18885
gene id: 365044:PNAP_RS18885
uniprot id: A1VTU7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CcoP / FixP family.
messages: Binds 2 heme C groups per subunit.
messages: C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex.
messages: Cell inner membrane
messages: Component of the cbb3-type cytochrome c oxidase.

365044:PNAP RS04795
gene id: 365044:PNAP_RS04795
uniprot id: A1VKV0
names: Similarity
messages: Belongs to the peptidase S14 family.

365044:PNAP RS01305
gene id: 365044:PNAP_RS01305
uniprot id: A1VIW1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the high-potential iron-sulfur protein (HiPIP) family.
messages: Homodimer.
messages: Specific class of high-redox-potential 4Fe-4S ferredoxins. Functions in anaerobic electron transport in most purple and in some other photosynthetic bacteria and in at least one genus (Paracoccus) of halophilic, denitrifying bacteria.

365044:PNAP RS03625
gene id: 365044:PNAP_RS03625
uniprot id: A1VK73
names: Function
names: Similarity
messages: Belongs to the PqqB family.
messages: May be involved in the transport of PQQ or its precursor to the periplasm.

365044:PNAP RS06235
gene id: 365044:PNAP_RS06235
uniprot id: A1VLN2
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

365044:PNAP RS03720
gene id: 365044:PNAP_RS03720
uniprot id: A1VK92
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

365044:PNAP RS06470
gene id: 365044:PNAP_RS06470
uniprot id: A1VLS7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

365044:PNAP RS02590
gene id: 365044:PNAP_RS02590
uniprot id: A1VJL4
names: Similarity
messages: Belongs to the HipA Ser/Thr kinase family.

365044:PNAP RS01025
gene id: 365044:PNAP_RS01025
uniprot id: A1VIQ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

365044:PNAP RS18265
gene id: 365044:PNAP_RS18265
uniprot id: A1VTH2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

365044:PNAP RS17985
gene id: 365044:PNAP_RS17985
uniprot id: A1VTC2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpA family.
messages: Cell inner membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds the periplasmic potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

365044:PNAP RS08985
gene id: 365044:PNAP_RS08985
uniprot id: A1VN77
names: Similarity
messages: Belongs to the heat shock protein 70 family.

365044:PNAP RS10225
gene id: 365044:PNAP_RS10225
uniprot id: A1VNX1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

365044:PNAP RS02485
gene id: 365044:PNAP_RS02485
uniprot id: A1VJJ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

365044:PNAP RS03405
gene id: 365044:PNAP_RS03405
uniprot id: A1VK29
names: Similarity
messages: Belongs to the MlaA family.

365044:PNAP RS04430
gene id: 365044:PNAP_RS04430
uniprot id: A1VKN0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell inner membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

365044:PNAP RS22350
gene id: 365044:PNAP_RS22350
uniprot id: A1VVU3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

365044:PNAP RS00620
gene id: 365044:PNAP_RS00620
uniprot id: A1VIH2
names: Cofactor
names: Function
messages: Binds 2 [4Fe-4S] clusters.
messages: Component of a complex that catalyzes the oxidation of glycolate to glyoxylate.

365044:PNAP RS00730
gene id: 365044:PNAP_RS00730
uniprot id: A1VIJ4
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

365044:PNAP RS06195
gene id: 365044:PNAP_RS06195
uniprot id: A1VLM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

365044:PNAP RS09205
gene id: 365044:PNAP_RS09205
uniprot id: A1VNC1
names: Subcellular Location Annotation
messages: Membrane

365044:PNAP RS14405
gene id: 365044:PNAP_RS14405
uniprot id: A1VRA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

365044:PNAP RS11945
gene id: 365044:PNAP_RS11945
uniprot id: A1VPW7
names: Function
names: Similarity
messages: Belongs to the Dus family. DusA subfamily.
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs.

365044:PNAP RS18435
gene id: 365044:PNAP_RS18435
uniprot id: A1VTK6
names: Similarity
messages: Belongs to the shaker potassium channel beta subunit family.

365044:PNAP RS07085
gene id: 365044:PNAP_RS07085
uniprot id: A1VM56
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

365044:PNAP RS02840
gene id: 365044:PNAP_RS02840
uniprot id: A1VJR4
names: PTM
messages: Binds 2 heme c groups covalently per subunit.

365044:PNAP RS20990
gene id: 365044:PNAP_RS20990
uniprot id: A1VV25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone-like protein H-NS family.
messages: nucleoid

365044:PNAP RS09860
gene id: 365044:PNAP_RS09860
uniprot id: A1VNP8
names: Similarity
messages: Belongs to the rubredoxin family.

365044:PNAP RS20025
gene id: 365044:PNAP_RS20025
uniprot id: A1VUI4
names: Similarity
messages: Belongs to the dihydropyrimidine dehydrogenase family.

365044:PNAP RS01255
gene id: 365044:PNAP_RS01255
uniprot id: A1VIV2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

365044:PNAP RS17595
gene id: 365044:PNAP_RS17595
uniprot id: A1VT43
names: Caution
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IcmF family.
messages: Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly.
messages: Homodimer.
messages: Is composed of four functional domains: the N-terminal 5'-deoxyadenosylcobalamin binding region that is homologous to the small subunit of ICM (IcmB), a middle P-loop GTPase domain (MeaI) that likely acts as a chaperone for ICM, a structured linker region involved in dimer formation, and a C-terminal part that is homologous to the large substrate-binding subunit of ICM (IcmA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

365044:PNAP RS13135
gene id: 365044:PNAP_RS13135
uniprot id: A1VQK4
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

365044:PNAP RS21205
gene id: 365044:PNAP_RS21205
uniprot id: A1VV71
names: Similarity
messages: Belongs to the MotB family.

365044:PNAP RS13030
gene id: 365044:PNAP_RS13030
uniprot id: A1VQI3
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

365044:PNAP RS18240
gene id: 365044:PNAP_RS18240
uniprot id: A1VTG7
names: Similarity
messages: Belongs to the TrpC family.

365044:PNAP RS11960
gene id: 365044:PNAP_RS11960
uniprot id: A1VPX0
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins.

365044:PNAP RS08115
gene id: 365044:PNAP_RS08115
uniprot id: A1VMR1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

365044:PNAP RS15290
gene id: 365044:PNAP_RS15290
uniprot id: A1VRS8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

365044:PNAP RS10745
gene id: 365044:PNAP_RS10745
uniprot id: A1VP72
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

365044:PNAP RS10685
gene id: 365044:PNAP_RS10685
uniprot id: A1VP61
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

365044:PNAP RS05265
gene id: 365044:PNAP_RS05265
uniprot id: A1VL46
names: Subcellular Location Annotation
messages: Membrane

365044:PNAP RS07825
gene id: 365044:PNAP_RS07825
uniprot id: A1VMK3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HesB/IscA family.
messages: Binds 1 iron-sulfur cluster per subunit.
messages: Homodimer.
messages: Required for insertion of 4Fe-4S clusters.

365044:PNAP RS09100
gene id: 365044:PNAP_RS09100
uniprot id: A1VNA0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

365044:PNAP RS19720
gene id: 365044:PNAP_RS19720
uniprot id: A1VUC3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

365044:PNAP RS11575
gene id: 365044:PNAP_RS11575
uniprot id: A1VPP4
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

365044:PNAP RS04880
gene id: 365044:PNAP_RS04880
uniprot id: A1VKW6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease gamma subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

365044:PNAP RS03040
gene id: 365044:PNAP_RS03040
uniprot id: A1VJV4
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

365044:PNAP RS05785
gene id: 365044:PNAP_RS05785
uniprot id: A1VLE3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Monomer.

365044:PNAP RS05170
gene id: 365044:PNAP_RS05170
uniprot id: A1VL27
names: Subcellular Location Annotation
messages: Membrane

365044:PNAP RS15060
gene id: 365044:PNAP_RS15060
uniprot id: A1VRN2
names: Caution
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

365044:PNAP RS05945
gene id: 365044:PNAP_RS05945
uniprot id: A1VLH4
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

365044:PNAP RS16880
gene id: 365044:PNAP_RS16880
uniprot id: A1VSP8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

365044:PNAP RS03190
gene id: 365044:PNAP_RS03190
uniprot id: A1VJY5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
messages: Homotetramer.

365044:PNAP RS04030
gene id: 365044:PNAP_RS04030
uniprot id: A1VKF2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

365044:PNAP RS21560
gene id: 365044:PNAP_RS21560
uniprot id: A1VVE2
names: Similarity
messages: Belongs to the HipA Ser/Thr kinase family.

365044:PNAP RS05935
gene id: 365044:PNAP_RS05935
uniprot id: A1VLH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

365044:PNAP RS03815
gene id: 365044:PNAP_RS03815
uniprot id: A1VKB0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

365044:PNAP RS08890
gene id: 365044:PNAP_RS08890
uniprot id: A1VN58
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

365044:PNAP RS11545
gene id: 365044:PNAP_RS11545
uniprot id: A1VPN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

365044:PNAP RS06400
gene id: 365044:PNAP_RS06400
uniprot id: A1VLR5
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

365044:PNAP RS12020
gene id: 365044:PNAP_RS12020
uniprot id: A1VPY1
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

365044:PNAP RS02495
gene id: 365044:PNAP_RS02495
uniprot id: A1VJJ5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HesB/IscA family.
messages: Binds 1 iron-sulfur cluster per subunit.
messages: Homodimer.
messages: Required for insertion of 4Fe-4S clusters.

365044:PNAP RS11465
gene id: 365044:PNAP_RS11465
uniprot id: A1VPM0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
messages: Cytoplasm
messages: Homodimer. Forms a heterotetramer with IscU, interacts with other sulfur acceptors.
messages: Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.

365044:PNAP RS07330
gene id: 365044:PNAP_RS07330
uniprot id: A1VMA4
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

365044:PNAP RS18065
gene id: 365044:PNAP_RS18065
uniprot id: A1VTD7
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

365044:PNAP RS09085
gene id: 365044:PNAP_RS09085
uniprot id: A1VN97
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZipA family.
messages: Cell inner membrane
messages: Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins.

365044:PNAP RS04980
gene id: 365044:PNAP_RS04980
uniprot id: A1VKY8
names: Subcellular Location Annotation
messages: Membrane

365044:PNAP RS08755
gene id: 365044:PNAP_RS08755
uniprot id: A1VM30
names: Function
names: Similarity
messages: Belongs to the transposase 11 family.
messages: Involved in the transposition of the insertion sequence IS5.

365044:PNAP RS10045
gene id: 365044:PNAP_RS10045
uniprot id: A1VNT5
names: Similarity
messages: Belongs to the ribosome association toxin RatA family.

365044:PNAP RS16775
gene id: 365044:PNAP_RS16775
uniprot id: A1VSM8
names: Similarity
messages: Belongs to the transcriptional regulatory Fis family.

365044:PNAP RS06115
gene id: 365044:PNAP_RS06115
uniprot id: A1VLK8
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

365044:PNAP RS10785
gene id: 365044:PNAP_RS10785
uniprot id: A1VP80
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Cob(I)alamin adenosyltransferase family.
messages: Cytoplasm
messages: Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids.

365044:PNAP RS20660
gene id: 365044:PNAP_RS20660
uniprot id: A1VUV6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

365044:PNAP RS09625
gene id: 365044:PNAP_RS09625
uniprot id: A1VNK2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Monomer.

365044:PNAP RS12690
gene id: 365044:PNAP_RS12690
uniprot id: A1VQB4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

365044:PNAP RS14570
gene id: 365044:PNAP_RS14570
uniprot id: A1VRE0
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

365044:PNAP RS08350
gene id: 365044:PNAP_RS08350
uniprot id: A1VMV5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

365044:PNAP RS14930
gene id: 365044:PNAP_RS14930
uniprot id: A1VRK6
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

365044:PNAP RS02505
gene id: 365044:PNAP_RS02505
uniprot id: A1VJJ7
names: Function
names: Similarity
messages: Belongs to the anhydro-N-acetylmuramic acid kinase family.
messages: Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.

365044:PNAP RS11045
gene id: 365044:PNAP_RS11045
uniprot id: A1VPD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Membrane

365044:PNAP RS07505
gene id: 365044:PNAP_RS07505
uniprot id: A1VMD8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial solute-binding protein 7 family.
messages: Homodimer.
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: Periplasm

365044:PNAP RS16795
gene id: 365044:PNAP_RS16795
uniprot id: A1VSN2
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

365044:PNAP RS27915
gene id: 365044:PNAP_RS27915
uniprot id: A1VQC3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

365044:PNAP RS03745
gene id: 365044:PNAP_RS03745
uniprot id: A1VK96
names: Similarity
messages: Belongs to the GSP E family.

365044:PNAP RS06035
gene id: 365044:PNAP_RS06035
uniprot id: A1VLJ2
names: Subcellular Location Annotation
messages: Membrane

365044:PNAP RS19160
gene id: 365044:PNAP_RS19160
uniprot id: A1VU03
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

365044:PNAP RS04025
gene id: 365044:PNAP_RS04025
uniprot id: A1VKF1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

365044:PNAP RS16675
gene id: 365044:PNAP_RS16675
uniprot id: A1VSK7
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

365044:PNAP RS18020
gene id: 365044:PNAP_RS18020
uniprot id: A1VTC8
names: Subcellular Location Annotation
messages: Membrane

365044:PNAP RS14975
gene id: 365044:PNAP_RS14975
uniprot id: A1VRL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

365044:PNAP RS04850
gene id: 365044:PNAP_RS04850
uniprot id: A1VKW0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
messages: Cytoplasm
messages: Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
messages: Homodimer. UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

365044:PNAP RS16505
gene id: 365044:PNAP_RS16505
uniprot id: A1VSH8
names: Similarity
messages: Belongs to the myoviridae tail sheath protein family.

365044:PNAP RS16375
gene id: 365044:PNAP_RS16375
uniprot id: A1VSF3
names: Cofactor
names: Function
messages: Accepts electrons from ETF and reduces ubiquinone.
messages: Binds 1 [4Fe-4S] cluster.

365044:PNAP RS12180
gene id: 365044:PNAP_RS12180
uniprot id: A1VQ13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

365044:PNAP RS07450
gene id: 365044:PNAP_RS07450
uniprot id: A1VMC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

365044:PNAP RS13490
gene id: 365044:PNAP_RS13490
uniprot id: A1VQS5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

365044:PNAP RS16050
gene id: 365044:PNAP_RS16050
uniprot id: A1VS87
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

365044:PNAP RS10320
gene id: 365044:PNAP_RS10320
uniprot id: A1VNY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

365044:PNAP RS20840
gene id: 365044:PNAP_RS20840
uniprot id: A1VUZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase type 1 family. AlkB subfamily.
messages: Cell inner membrane
messages: Membrane

365044:PNAP RS04145
gene id: 365044:PNAP_RS04145
uniprot id: A1VKH3
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

365044:PNAP RS04725
gene id: 365044:PNAP_RS04725
uniprot id: A1VKT6
names: Function
names: Similarity
messages: Belongs to the CitG/MdcB family.
messages: Involved in the formation of 2-(5''-phosphoribosyl)-3'-dephosphocoenzyme-A, the prosthetic group of the acyl-carrier protein of the malonate decarboxylase.

365044:PNAP RS04370
gene id: 365044:PNAP_RS04370
uniprot id: A1VKL8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

365044:PNAP RS22340
gene id: 365044:PNAP_RS22340
uniprot id: A1VVU1
names: Similarity
messages: Belongs to the phosphohexose mutase family.

365044:PNAP RS04090
gene id: 365044:PNAP_RS04090
uniprot id: A1VKG3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.
messages: In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: In the N-terminal section; belongs to the MIP18 family.

365044:PNAP RS09545
gene id: 365044:PNAP_RS09545
uniprot id: A1VNI8
names: Subcellular Location Annotation
messages: Membrane

365044:PNAP RS01215
gene id: 365044:PNAP_RS01215
uniprot id: A1VIU4
names: Subcellular Location Annotation
messages: Membrane

365044:PNAP RS05930
gene id: 365044:PNAP_RS05930
uniprot id: A1VLH1
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

365044:PNAP RS00510
gene id: 365044:PNAP_RS00510
uniprot id: A1VIE9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.
messages: Cytoplasm
messages: Monomer.

365044:PNAP RS03805
gene id: 365044:PNAP_RS03805
uniprot id: A1VKA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

365044:PNAP RS17100
gene id: 365044:PNAP_RS17100
uniprot id: A1VSU4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

365044:PNAP RS09070
gene id: 365044:PNAP_RS09070
uniprot id: A1VN94
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family.
messages: Cytoplasm
messages: Homotrimer.

365044:PNAP RS08430
gene id: 365044:PNAP_RS08430
uniprot id: A1VMX2
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

365044:PNAP RS19415
gene id: 365044:PNAP_RS19415
uniprot id: A1VU52
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

365044:PNAP RS07965
gene id: 365044:PNAP_RS07965
uniprot id: A1VMN1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

365044:PNAP RS07510
gene id: 365044:PNAP_RS07510
uniprot id: A1VMD9
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.

365044:PNAP RS19255
gene id: 365044:PNAP_RS19255
uniprot id: A1VU21
names: Subcellular Location Annotation
messages: Periplasm

365044:PNAP RS02870
gene id: 365044:PNAP_RS02870
uniprot id: A1VJS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

365044:PNAP RS16910
gene id: 365044:PNAP_RS16910
uniprot id: A1VSQ4
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

365044:PNAP RS12845
gene id: 365044:PNAP_RS12845
uniprot id: A1VQE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

365044:PNAP RS19940
gene id: 365044:PNAP_RS19940
uniprot id: A1VUG7
names: Subcellular Location Annotation
messages: Membrane

365044:PNAP RS07345
gene id: 365044:PNAP_RS07345
uniprot id: A1VMA7
names: Similarity
messages: Belongs to the DEAD box helicase family.

365044:PNAP RS05270
gene id: 365044:PNAP_RS05270
uniprot id: A1VL47
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

365044:PNAP RS15020
gene id: 365044:PNAP_RS15020
uniprot id: A1VRM4
names: Similarity
messages: Belongs to the UPF0162 family.

365044:PNAP RS08590
gene id: 365044:PNAP_RS08590
uniprot id: A1VN04
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.

365044:PNAP RS10775
gene id: 365044:PNAP_RS10775
uniprot id: A1VP78
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

365044:PNAP RS20865
gene id: 365044:PNAP_RS20865
uniprot id: A1VUZ6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

365044:PNAP RS05745
gene id: 365044:PNAP_RS05745
uniprot id: A1VLD5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

365044:PNAP RS03740
gene id: 365044:PNAP_RS03740
uniprot id: A1VK95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

365044:PNAP RS08635
gene id: 365044:PNAP_RS08635
uniprot id: A1VN13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

365044:PNAP RS13870
gene id: 365044:PNAP_RS13870
uniprot id: A1VR01
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes.

365044:PNAP RS14205
gene id: 365044:PNAP_RS14205
uniprot id: A1VR67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

365044:PNAP RS12745
gene id: 365044:PNAP_RS12745
uniprot id: A1VQC5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

365044:PNAP RS07535
gene id: 365044:PNAP_RS07535
uniprot id: A1VME5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

365044:PNAP RS20915
gene id: 365044:PNAP_RS20915
uniprot id: A1VV06
names: Subcellular Location Annotation
messages: Membrane

365044:PNAP RS15115
gene id: 365044:PNAP_RS15115
uniprot id: A1VRP3
names: Similarity
messages: Belongs to the band 7/mec-2 family. Flotillin subfamily.

365044:PNAP RS14470
gene id: 365044:PNAP_RS14470
uniprot id: A1VRB8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxH family.
messages: Binds 2 Mn(2+) ions per subunit in a binuclear metal center.
messages: Cell inner membrane
messages: Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

365044:PNAP RS11450
gene id: 365044:PNAP_RS11450
uniprot id: A1VPL7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HscB family.
messages: Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA.
messages: Interacts with HscA and stimulates its ATPase activity.

365044:PNAP RS03445
gene id: 365044:PNAP_RS03445
uniprot id: A1VK37
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

365044:PNAP RS22610
gene id: 365044:PNAP_RS22610
uniprot id: A1VVZ7
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

365044:PNAP RS07610
gene id: 365044:PNAP_RS07610
uniprot id: A1VMG0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

365044:PNAP RS16840
gene id: 365044:PNAP_RS16840
uniprot id: A1VSP0
names: Caution
names: Function
names: Similarity
messages: Belongs to the UbiX/PAD1 family.
messages: Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

365044:PNAP RS20430
gene id: 365044:PNAP_RS20430
uniprot id: A1VUR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

365044:PNAP RS02265
gene id: 365044:PNAP_RS02265
uniprot id: A1VJF1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AceK family.
messages: Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation.
messages: Cytoplasm

365044:PNAP RS10690
gene id: 365044:PNAP_RS10690
uniprot id: A1VP62
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

365044:PNAP RS15175
gene id: 365044:PNAP_RS15175
uniprot id: A1VRQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Cell inner membrane
messages: Membrane

365044:PNAP RS05765
gene id: 365044:PNAP_RS05765
uniprot id: A1VLD9
names: Similarity
messages: Belongs to the UPF0111 family.

365044:PNAP RS03505
gene id: 365044:PNAP_RS03505
uniprot id: A1VK49
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

365044:PNAP RS05770
gene id: 365044:PNAP_RS05770
uniprot id: A1VLE0
names: Subcellular Location Annotation
messages: Membrane

365044:PNAP RS06290
gene id: 365044:PNAP_RS06290
uniprot id: A1VLP3
names: Similarity
messages: Belongs to the UPF0423 family.

365044:PNAP RS06630
gene id: 365044:PNAP_RS06630
uniprot id: A1VLW0
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

365044:PNAP RS09300
gene id: 365044:PNAP_RS09300
uniprot id: A1VND8
names: Function
names: Similarity
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.
messages: E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

365044:PNAP RS02410
gene id: 365044:PNAP_RS02410
uniprot id: A1VJH8
names: Subcellular Location Annotation
messages: Membrane

365044:PNAP RS18480
gene id: 365044:PNAP_RS18480
uniprot id: A1VTL5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

365044:PNAP RS16010
gene id: 365044:PNAP_RS16010
uniprot id: A1VS79
names: Function
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.
messages: DNA-dependent ATPase that plays important roles in cellular responses to stalled DNA replication processes.

365044:PNAP RS07910
gene id: 365044:PNAP_RS07910
uniprot id: A1VMM1
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

365044:PNAP RS09335
gene id: 365044:PNAP_RS09335
uniprot id: A1VNE6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamD family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

365044:PNAP RS24215
gene id: 365044:PNAP_RS24215
uniprot id: A1VWW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone-like protein H-NS family.
messages: nucleoid

365044:PNAP RS06555
gene id: 365044:PNAP_RS06555
uniprot id: A1VLU5
names: Similarity
messages: Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily.

365044:PNAP RS04345
gene id: 365044:PNAP_RS04345
uniprot id: A1VKL3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.

365044:PNAP RS04765
gene id: 365044:PNAP_RS04765
uniprot id: A1VKU4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

365044:PNAP RS18590
gene id: 365044:PNAP_RS18590
uniprot id: A1VTN6
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

365044:PNAP RS19340
gene id: 365044:PNAP_RS19340
uniprot id: A1VU38
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

365044:PNAP RS20080
gene id: 365044:PNAP_RS20080
uniprot id: A1VUJ3
names: Similarity
messages: Belongs to the cytochrome P450 family.

365044:PNAP RS22425
gene id: 365044:PNAP_RS22425
uniprot id: A1VVV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

365044:PNAP RS02270
gene id: 365044:PNAP_RS02270
uniprot id: A1VJF2
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

365044:PNAP RS17895
gene id: 365044:PNAP_RS17895
uniprot id: A1VTA4
names: Similarity
messages: Belongs to the YkuD family.

365044:PNAP RS02525
gene id: 365044:PNAP_RS02525
uniprot id: A1VJK1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

365044:PNAP RS06945
gene id: 365044:PNAP_RS06945
uniprot id: A1VM24
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

365044:PNAP RS02735
gene id: 365044:PNAP_RS02735
uniprot id: A1VJP2
names: Subcellular Location Annotation
messages: Membrane

365044:PNAP RS15140
gene id: 365044:PNAP_RS15140
uniprot id: A1VRP8
names: Cofactor
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.

365044:PNAP RS11630
gene id: 365044:PNAP_RS11630
uniprot id: A1VPQ5
names: Function
names: Similarity
messages: Belongs to the NifD/NifK/NifE/NifN family.
messages: This protein may play a role in the biosynthesis of the prosthetic group of nitrogenase (FeMo cofactor).

365044:PNAP RS04000
gene id: 365044:PNAP_RS04000
uniprot id: A1VKE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

365044:PNAP RS03690
gene id: 365044:PNAP_RS03690
uniprot id: A1VK86
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

365044:PNAP RS18165
gene id: 365044:PNAP_RS18165
uniprot id: A1VTF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

365044:PNAP RS10065
gene id: 365044:PNAP_RS10065
uniprot id: A1VNT9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

365044:PNAP RS09605
gene id: 365044:PNAP_RS09605
uniprot id: A1VNJ8
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

365044:PNAP RS14960
gene id: 365044:PNAP_RS14960
uniprot id: A1VRL2
names: Function
names: Similarity
messages: Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

365044:PNAP RS12940
gene id: 365044:PNAP_RS12940
uniprot id: A1VQG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Cell membrane
messages: Membrane

365044:PNAP RS15920
gene id: 365044:PNAP_RS15920
uniprot id: A1VS60
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.
messages: Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

365044:PNAP RS10695
gene id: 365044:PNAP_RS10695
uniprot id: A1VP63
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

365044:PNAP RS11570
gene id: 365044:PNAP_RS11570
uniprot id: A1VPP3
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

365044:PNAP RS00670
gene id: 365044:PNAP_RS00670
uniprot id: A1VII2
names: Similarity
messages: Belongs to the ketopantoate reductase family.

365044:PNAP RS10085
gene id: 365044:PNAP_RS10085
uniprot id: A1VNU3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

365044:PNAP RS05615
gene id: 365044:PNAP_RS05615
uniprot id: A1VLA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

365044:PNAP RS20300
gene id: 365044:PNAP_RS20300
uniprot id: A1VUN5
names: Similarity
messages: Belongs to the barstar family.

365044:PNAP RS10290
gene id: 365044:PNAP_RS10290
uniprot id: A1VNY1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TolB family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: Periplasm
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

365044:PNAP RS07295
gene id: 365044:PNAP_RS07295
uniprot id: A1VM97
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

365044:PNAP RS18185
gene id: 365044:PNAP_RS18185
uniprot id: A1VTG0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

365044:PNAP RS17260
gene id: 365044:PNAP_RS17260
uniprot id: A1VSX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

365044:PNAP RS23295
gene id: 365044:PNAP_RS23295
uniprot id: A1VWD2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. DnaE2 subfamily.
messages: Cytoplasm
messages: DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase.

365044:PNAP RS08140
gene id: 365044:PNAP_RS08140
uniprot id: A1VMR6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

365044:PNAP RS05445
gene id: 365044:PNAP_RS05445
uniprot id: A1VL81
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

365044:PNAP RS14210
gene id: 365044:PNAP_RS14210
uniprot id: A1VR68
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

365044:PNAP RS23155
gene id: 365044:PNAP_RS23155
uniprot id: A1VWA4
names: Cofactor
names: PTM
names: Subcellular Location Annotation
messages: Binds 2 heme groups per subunit.
messages: Binds 2 heme groups.
messages: Periplasm

365044:PNAP RS07695
gene id: 365044:PNAP_RS07695
uniprot id: A1VMH7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

365044:PNAP RS15630
gene id: 365044:PNAP_RS15630
uniprot id: A1VRZ6
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

365044:PNAP RS14295
gene id: 365044:PNAP_RS14295
uniprot id: A1VR84
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein PotD/PotF family.
messages: Periplasm
messages: Required for the activity of the bacterial periplasmic transport system of putrescine.

365044:PNAP RS18515
gene id: 365044:PNAP_RS18515
uniprot id: A1VTM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TPS (TC 1.B.20) family.
messages: Cell outer membrane
messages: Membrane

365044:PNAP RS02550
gene id: 365044:PNAP_RS02550
uniprot id: A1VJK6
names: Similarity
messages: Belongs to the DSD1 family.

365044:PNAP RS00550
gene id: 365044:PNAP_RS00550
uniprot id: A1VIF8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
messages: In the native structure, TdcB is in a dimeric form, whereas in the TdcB-AMP complex, it exists in a tetrameric form (dimer of dimers).
messages: TdcB also dehydrates serine to yield pyruvate via analogous enamine/imine intermediates.

365044:PNAP RS09540
gene id: 365044:PNAP_RS09540
uniprot id: A1VNI7
names: Subcellular Location Annotation
messages: Membrane

365044:PNAP RS18980
gene id: 365044:PNAP_RS18980
uniprot id: A1VTW6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PNT beta subunit family.
messages: Cell inner membrane
messages: Membrane
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

365044:PNAP RS04665
gene id: 365044:PNAP_RS04665
uniprot id: A1VKS5
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

365044:PNAP RS05455
gene id: 365044:PNAP_RS05455
uniprot id: A1VL83
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Monomer.

365044:PNAP RS04005
gene id: 365044:PNAP_RS04005
uniprot id: A1VKE7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

365044:PNAP RS11830
gene id: 365044:PNAP_RS11830
uniprot id: A1VPU4
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

365044:PNAP RS02420
gene id: 365044:PNAP_RS02420
uniprot id: A1VJI0
names: Similarity
messages: Belongs to the leucine-binding protein family.

365044:PNAP RS25975
gene id: 365044:PNAP_RS25975
uniprot id: A1VUS8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

365044:PNAP RS16770
gene id: 365044:PNAP_RS16770
uniprot id: A1VSM7
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

365044:PNAP RS16095
gene id: 365044:PNAP_RS16095
uniprot id: A1VS96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0187 family.
messages: Membrane

365044:PNAP RS08295
gene id: 365044:PNAP_RS08295
uniprot id: A1VMU5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

365044:PNAP RS03395
gene id: 365044:PNAP_RS03395
uniprot id: A1VK27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MlaE permease family.
messages: Cell inner membrane
messages: Membrane

365044:PNAP RS18915
gene id: 365044:PNAP_RS18915
uniprot id: A1VTV3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LptE lipoprotein family.
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptD.
messages: Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane.

365044:PNAP RS10210
gene id: 365044:PNAP_RS10210
uniprot id: A1VNW8
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

365044:PNAP RS06565
gene id: 365044:PNAP_RS06565
uniprot id: A1VLU7
names: Subcellular Location Annotation
messages: Membrane

365044:PNAP RS01760
gene id: 365044:PNAP_RS01760
uniprot id: A1VJ51
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.
messages: Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU).
messages: Homotetramer.

365044:PNAP RS16385
gene id: 365044:PNAP_RS16385
uniprot id: A1VSF5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

365044:PNAP RS13660
gene id: 365044:PNAP_RS13660
uniprot id: A1VQV9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

365044:PNAP RS18135
gene id: 365044:PNAP_RS18135
uniprot id: A1VTF0
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

365044:PNAP RS09490
gene id: 365044:PNAP_RS09490
uniprot id: A1VNH7
names: Similarity
messages: Belongs to the peptidase C56 family.

365044:PNAP RS15165
gene id: 365044:PNAP_RS15165
uniprot id: A1VRQ3
names: Cofactor
names: Subunit
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD. The complex can form homotrimers.
messages: The heme is bound between the two transmembrane subunits.

365044:PNAP RS22335
gene id: 365044:PNAP_RS22335
uniprot id: A1VVU0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 2 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

365044:PNAP RS08395
gene id: 365044:PNAP_RS08395
uniprot id: A1VMW5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

365044:PNAP RS00490
gene id: 365044:PNAP_RS00490
uniprot id: A1VIE5
names: Similarity
messages: Belongs to the universal stress protein A family.

365044:PNAP RS20630
gene id: 365044:PNAP_RS20630
uniprot id: A1VUV0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the AB hydrolase superfamily. BphD family.
messages: Catalyzes an unusual C-C bond hydrolysis of 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoic acid (HOPDA) to produce benzoic acid and 2-hydroxy-2,4-pentadienoic acid (HPD).
messages: Homodimer.

365044:PNAP RS20035
gene id: 365044:PNAP_RS20035
uniprot id: A1VUI6
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20 family.
messages: Binds 2 Zn(2+) ions per subunit.

365044:PNAP RS00210
gene id: 365044:PNAP_RS00210
uniprot id: A1VI88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

365044:PNAP RS09840
gene id: 365044:PNAP_RS09840
uniprot id: A1VNP4
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily.

365044:PNAP RS03810
gene id: 365044:PNAP_RS03810
uniprot id: A1VKA9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Plays an essential role in type IV pili and type II pseudopili formation by proteolytically removing the leader sequence from substrate proteins and subsequently monomethylating the alpha-amino group of the newly exposed N-terminal phenylalanine.

365044:PNAP RS15310
gene id: 365044:PNAP_RS15310
uniprot id: A1VRT2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

365044:PNAP RS21020
gene id: 365044:PNAP_RS21020
uniprot id: A1VV32
names: Similarity
messages: Belongs to the TrbE/VirB4 family.

365044:PNAP RS17195
gene id: 365044:PNAP_RS17195
uniprot id: A1VSW2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

365044:PNAP RS05675
gene id: 365044:PNAP_RS05675
uniprot id: A1VLC1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

365044:PNAP RS08645
gene id: 365044:PNAP_RS08645
uniprot id: A1VN15
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the aerobic coproporphyrinogen-III oxidase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.

365044:PNAP RS20030
gene id: 365044:PNAP_RS20030
uniprot id: A1VUI5
names: PTM
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.
messages: Carbamylation allows a single lysine to coordinate two divalent metal cations.

365044:PNAP RS10030
gene id: 365044:PNAP_RS10030
uniprot id: A1VNT2
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

365044:PNAP RS17345
gene id: 365044:PNAP_RS17345
uniprot id: A1VSZ2
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

365044:PNAP RS10680
gene id: 365044:PNAP_RS10680
uniprot id: A1VP60
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

365044:PNAP RS13320
gene id: 365044:PNAP_RS13320
uniprot id: A1VQP0
names: Similarity
messages: Belongs to the IlvD/Edd family.

365044:PNAP RS13665
gene id: 365044:PNAP_RS13665
uniprot id: A1VQW0
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

365044:PNAP RS02455
gene id: 365044:PNAP_RS02455
uniprot id: A1VJI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

365044:PNAP RS23055
gene id: 365044:PNAP_RS23055
uniprot id: A1VW83
names: Similarity
messages: Belongs to the acylphosphatase family.

365044:PNAP RS12435
gene id: 365044:PNAP_RS12435
uniprot id: A1VQ66
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

365044:PNAP RS11820
gene id: 365044:PNAP_RS11820
uniprot id: A1VPU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

365044:PNAP RS10655
gene id: 365044:PNAP_RS10655
uniprot id: A1VP55
names: Caution
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
messages: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

365044:PNAP RS09650
gene id: 365044:PNAP_RS09650
uniprot id: A1VNK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

365044:PNAP RS20220
gene id: 365044:PNAP_RS20220
uniprot id: A1VUL9
names: Similarity
messages: Belongs to the transketolase family.

365044:PNAP RS12885
gene id: 365044:PNAP_RS12885
uniprot id: A1VQF3
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

365044:PNAP RS14170
gene id: 365044:PNAP_RS14170
uniprot id: A1VR61
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

365044:PNAP RS10915
gene id: 365044:PNAP_RS10915
uniprot id: A1VPA7
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetyltransferase family. ArgA subfamily.
messages: Cytoplasm
messages: In bacteria which possess the bifunctional enzyme ornithine acetyltransferase/N-acetylglutamate synthase (ArgJ), ArgA fulfills an anaplerotic role.

365044:PNAP RS00370
gene id: 365044:PNAP_RS00370
uniprot id: A1VIB9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

365044:PNAP RS00475
gene id: 365044:PNAP_RS00475
uniprot id: A1VIE2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

365044:PNAP RS08385
gene id: 365044:PNAP_RS08385
uniprot id: A1VMW3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-beta-lactamase superfamily. Class-B beta-lactamase family.
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Monomer.
messages: Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.

365044:PNAP RS17775
gene id: 365044:PNAP_RS17775
uniprot id: A1VT80
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M15D family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide.

365044:PNAP RS07500
gene id: 365044:PNAP_RS07500
uniprot id: A1VMD7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

365044:PNAP RS03425
gene id: 365044:PNAP_RS03425
uniprot id: A1VK33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

365044:PNAP RS12890
gene id: 365044:PNAP_RS12890
uniprot id: A1VQF4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

365044:PNAP RS17165
gene id: 365044:PNAP_RS17165
uniprot id: A1VSV6
names: Similarity
messages: Belongs to the DapA family.

365044:PNAP RS03030
gene id: 365044:PNAP_RS03030
uniprot id: A1VJV2
names: Cofactor
names: Similarity
messages: Belongs to the carotenoid oxygenase family.
messages: Binds 1 Fe(2+) ion per subunit.

365044:PNAP RS19780
gene id: 365044:PNAP_RS19780
uniprot id: A1VUD5
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

365044:PNAP RS04300
gene id: 365044:PNAP_RS04300
uniprot id: A1VKK4
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit A family.

365044:PNAP RS09115
gene id: 365044:PNAP_RS09115
uniprot id: A1VNA3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: In the N-terminal section; belongs to the FGAMS family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.

365044:PNAP RS18740
gene id: 365044:PNAP_RS18740
uniprot id: A1VTR7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
messages: Cell inner membrane
messages: Transport of potassium into the cell. Likely operates as a K(+):H(+) symporter.

365044:PNAP RS17220
gene id: 365044:PNAP_RS17220
uniprot id: A1VSW7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane

365044:PNAP RS19480
gene id: 365044:PNAP_RS19480
uniprot id: A1VU66
names: Function
names: Similarity
messages: Belongs to the GlnE family.
messages: Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell.

365044:PNAP RS07575
gene id: 365044:PNAP_RS07575
uniprot id: A1VMF3
names: Similarity
messages: Belongs to the oxoprolinase family.

365044:PNAP RS20260
gene id: 365044:PNAP_RS20260
uniprot id: A1VUM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

365044:PNAP RS09895
gene id: 365044:PNAP_RS09895
uniprot id: A1VNQ5
names: Similarity
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.

365044:PNAP RS17700
gene id: 365044:PNAP_RS17700
uniprot id: A1VT65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

365044:PNAP RS14440
gene id: 365044:PNAP_RS14440
uniprot id: A1VRB2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

365044:PNAP RS05610
gene id: 365044:PNAP_RS05610
uniprot id: A1VLA8
names: Cofactor
names: Similarity
messages: Belongs to the 4HPPD family.
messages: Binds 1 Fe cation per subunit.

365044:PNAP RS02275
gene id: 365044:PNAP_RS02275
uniprot id: A1VJF3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

365044:PNAP RS13380
gene id: 365044:PNAP_RS13380
uniprot id: A1VQQ3
names: Cofactor
names: Function
messages: Accepts electrons from ETF and reduces ubiquinone.
messages: Binds 1 [4Fe-4S] cluster.

365044:PNAP RS10900
gene id: 365044:PNAP_RS10900
uniprot id: A1VPA3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

365044:PNAP RS17205
gene id: 365044:PNAP_RS17205
uniprot id: A1VSW4
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

365044:PNAP RS05205
gene id: 365044:PNAP_RS05205
uniprot id: A1VL34
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

365044:PNAP RS08120
gene id: 365044:PNAP_RS08120
uniprot id: A1VMR2
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 104 family.
messages: Protein-arginine rhamnosyltransferase that catalyzes the transfer of a single rhamnose to elongation factor P (EF-P) on 'Lys-32', a modification required for EF-P-dependent rescue of polyproline stalled ribosomes.

365044:PNAP RS18820
gene id: 365044:PNAP_RS18820
uniprot id: A1VTT3
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

365044:PNAP RS09630
gene id: 365044:PNAP_RS09630
uniprot id: A1VNK3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

365044:PNAP RS14240
gene id: 365044:PNAP_RS14240
uniprot id: A1VR73
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

365044:PNAP RS13400
gene id: 365044:PNAP_RS13400
uniprot id: A1VQQ7
names: Similarity
messages: Belongs to the GcvT family.

365044:PNAP RS11215
gene id: 365044:PNAP_RS11215
uniprot id: A1VPG9
names: Similarity
messages: Belongs to the glycosyl hydrolase 24 family.

365044:PNAP RS13005
gene id: 365044:PNAP_RS13005
uniprot id: A1VQH8
names: Subcellular Location Annotation
messages: Membrane

365044:PNAP RS04175
gene id: 365044:PNAP_RS04175
uniprot id: A1VKH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

365044:PNAP RS03980
gene id: 365044:PNAP_RS03980
uniprot id: A1VKE2
names: Subcellular Location Annotation
messages: Membrane

365044:PNAP RS05275
gene id: 365044:PNAP_RS05275
uniprot id: A1VL48
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

365044:PNAP RS10605
gene id: 365044:PNAP_RS10605
uniprot id: A1VP45
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

365044:PNAP RS20900
gene id: 365044:PNAP_RS20900
uniprot id: A1VV03
names: Similarity
messages: Belongs to the TrbE/VirB4 family.

365044:PNAP RS05660
gene id: 365044:PNAP_RS05660
uniprot id: A1VLB8
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. GlucD subfamily.

365044:PNAP RS03610
gene id: 365044:PNAP_RS03610
uniprot id: A1VK70
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. PqqE family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the cross-linking of a glutamate residue and a tyrosine residue in the PqqA protein as part of the biosynthesis of pyrroloquinoline quinone (PQQ).
messages: Interacts with PqqD. The interaction is necessary for activity of PqqE.

365044:PNAP RS19090
gene id: 365044:PNAP_RS19090
uniprot id: A1VTY9
names: Subcellular Location Annotation
messages: Membrane

365044:PNAP RS09200
gene id: 365044:PNAP_RS09200
uniprot id: A1VNC0
names: Subcellular Location Annotation
messages: Membrane

365044:PNAP RS06125
gene id: 365044:PNAP_RS06125
uniprot id: A1VLL0
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

365044:PNAP RS07140
gene id: 365044:PNAP_RS07140
uniprot id: A1VM66
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the complex I 75 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

365044:PNAP RS11150
gene id: 365044:PNAP_RS11150
uniprot id: A1VPF5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK.

365044:PNAP RS23440
gene id: 365044:PNAP_RS23440
uniprot id: A1VWG0
names: Similarity
messages: Belongs to the HsdR family.

365044:PNAP RS05795
gene id: 365044:PNAP_RS05795
uniprot id: A1VLE5
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

365044:PNAP RS03650
gene id: 365044:PNAP_RS03650
uniprot id: A1VK78
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

365044:PNAP RS07815
gene id: 365044:PNAP_RS07815
uniprot id: A1VMK1
names: Function
names: Similarity
messages: Belongs to the heat shock protein 70 family.
messages: Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB.

365044:PNAP RS09795
gene id: 365044:PNAP_RS09795
uniprot id: A1VNN5
names: Similarity
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.

365044:PNAP RS08260
gene id: 365044:PNAP_RS08260
uniprot id: A1VMT8
names: Subcellular Location Annotation
messages: Membrane

365044:PNAP RS02435
gene id: 365044:PNAP_RS02435
uniprot id: A1VJI3
names: Similarity
messages: Belongs to the TlyA family.

365044:PNAP RS03655
gene id: 365044:PNAP_RS03655
uniprot id: A1VK79
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell inner membrane
messages: Cytoplasm
messages: May bind 1 zinc ion per subunit.
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

365044:PNAP RS03620
gene id: 365044:PNAP_RS03620
uniprot id: A1VK72
names: Function
names: Similarity
messages: Belongs to the PqqC family.
messages: Ring cyclization and eight-electron oxidation of 3a-(2-amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline-7,9-dicarboxylic-acid to PQQ.

365044:PNAP RS01440
gene id: 365044:PNAP_RS01440
uniprot id: A1VIY6
names: Subcellular Location Annotation
messages: Membrane

365044:PNAP RS09180
gene id: 365044:PNAP_RS09180
uniprot id: A1VNB6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YciB family.
messages: Cell inner membrane
messages: Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.

365044:PNAP RS09080
gene id: 365044:PNAP_RS09080
uniprot id: A1VN96
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

365044:PNAP RS03850
gene id: 365044:PNAP_RS03850
uniprot id: A1VKB7
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

365044:PNAP RS01205
gene id: 365044:PNAP_RS01205
uniprot id: A1VIU2
names: Similarity
messages: Belongs to the UPF0250 family.

365044:PNAP RS06015
gene id: 365044:PNAP_RS06015
uniprot id: A1VLI8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.
messages: Cell membrane
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

365044:PNAP RS02255
gene id: 365044:PNAP_RS02255
uniprot id: A1VJE9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

365044:PNAP RS05720
gene id: 365044:PNAP_RS05720
uniprot id: A1VLD0
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

365044:PNAP RS16085
gene id: 365044:PNAP_RS16085
uniprot id: A1VS94
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

365044:PNAP RS23395
gene id: 365044:PNAP_RS23395
uniprot id: A1VWF2
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

365044:PNAP RS06915
gene id: 365044:PNAP_RS06915
uniprot id: A1VM18
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

365044:PNAP RS01380
gene id: 365044:PNAP_RS01380
uniprot id: A1VIX4
names: Similarity
messages: Belongs to the GSP E family.

365044:PNAP RS22730
gene id: 365044:PNAP_RS22730
uniprot id: A1VW18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone-like protein H-NS family.
messages: nucleoid

365044:PNAP RS12495
gene id: 365044:PNAP_RS12495
uniprot id: A1VQ79
names: Similarity
messages: Belongs to the TrbE/VirB4 family.

365044:PNAP RS11535
gene id: 365044:PNAP_RS11535
uniprot id: A1VPN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

365044:PNAP RS19755
gene id: 365044:PNAP_RS19755
uniprot id: A1VUD0
names: Similarity
messages: Belongs to the type IA topoisomerase family.

365044:PNAP RS10440
gene id: 365044:PNAP_RS10440
uniprot id: A1VP11
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

365044:PNAP RS13990
gene id: 365044:PNAP_RS13990
uniprot id: A1VR25
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily.
messages: Binds 1 NADP(+) per subunit.
messages: Catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose.
messages: Contains a large N-terminal NADP-binding domain, and a smaller C-terminal substrate-binding domain.
messages: Homopentamer.

365044:PNAP RS05055
gene id: 365044:PNAP_RS05055
uniprot id: A1VL04
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

365044:PNAP RS13310
gene id: 365044:PNAP_RS13310
uniprot id: A1VQN8
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

365044:PNAP RS04635
gene id: 365044:PNAP_RS04635
uniprot id: A1VKR9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecB family.
messages: Cytoplasm
messages: Homotetramer, a dimer of dimers. One homotetramer interacts with 1 SecA dimer.
messages: One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.

365044:PNAP RS08920
gene id: 365044:PNAP_RS08920
uniprot id: A1VN64
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 2 lipoyl cofactors covalently.
messages: Forms a 24-polypeptide structural core with octahedral symmetry.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

365044:PNAP RS09125
gene id: 365044:PNAP_RS09125
uniprot id: A1VNA5
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

365044:PNAP RS09930
gene id: 365044:PNAP_RS09930
uniprot id: A1VNR2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

365044:PNAP RS03500
gene id: 365044:PNAP_RS03500
uniprot id: A1VK48
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatB family.
messages: Cell inner membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

365044:PNAP RS03465
gene id: 365044:PNAP_RS03465
uniprot id: A1VK41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

365044:PNAP RS01010
gene id: 365044:PNAP_RS01010
uniprot id: A1VIQ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

365044:PNAP RS13625
gene id: 365044:PNAP_RS13625
uniprot id: A1VQV2
names: Subcellular Location Annotation
messages: Membrane

365044:PNAP RS04730
gene id: 365044:PNAP_RS04730
uniprot id: A1VKT7
names: PTM
names: Subcellular Location Annotation
messages: Covalently binds the prosthetic group of malonate decarboxylase.
messages: Cytoplasm

365044:PNAP RS23115
gene id: 365044:PNAP_RS23115
uniprot id: A1VW95
names: Subcellular Location Annotation
messages: Membrane

365044:PNAP RS20005
gene id: 365044:PNAP_RS20005
uniprot id: A1VUI0
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

365044:PNAP RS06110
gene id: 365044:PNAP_RS06110
uniprot id: A1VLK7
names: Similarity
messages: Belongs to the histone deacetylase family.

365044:PNAP RS04495
gene id: 365044:PNAP_RS04495
uniprot id: A1VKP2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

365044:PNAP RS10285
gene id: 365044:PNAP_RS10285
uniprot id: A1VNY0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Pal lipoprotein family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

365044:PNAP RS17055
gene id: 365044:PNAP_RS17055
uniprot id: A1VST5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

365044:PNAP RS04670
gene id: 365044:PNAP_RS04670
uniprot id: A1VKS6
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

365044:PNAP RS17380
gene id: 365044:PNAP_RS17380
uniprot id: A1VSZ9
names: Similarity
messages: Belongs to the polysaccharide synthase family.

365044:PNAP RS06610
gene id: 365044:PNAP_RS06610
uniprot id: A1VLV5
names: Similarity
messages: Belongs to the ice-binding protein family.

365044:PNAP RS03200
gene id: 365044:PNAP_RS03200
uniprot id: A1VJY7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COQ7 family.
messages: Binds 2 iron ions per subunit.
messages: Catalyzes the hydroxylation of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol during ubiquinone biosynthesis.
messages: Cell membrane

365044:PNAP RS03295
gene id: 365044:PNAP_RS03295
uniprot id: A1VK06
names: Subcellular Location Annotation
messages: Membrane

365044:PNAP RS18315
gene id: 365044:PNAP_RS18315
uniprot id: A1VTI2
names: Function
names: Similarity
messages: ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
messages: Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.

365044:PNAP RS15400
gene id: 365044:PNAP_RS15400
uniprot id: A1VRV0
names: Function
names: Similarity
messages: Belongs to the DUF177 domain family.
messages: Plays a role in synthesis, processing and/or stability of 23S rRNA.

365044:PNAP RS17075
gene id: 365044:PNAP_RS17075
uniprot id: A1VST9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell inner membrane

365044:PNAP RS03735
gene id: 365044:PNAP_RS03735
uniprot id: A1VK94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

365044:PNAP RS02970
gene id: 365044:PNAP_RS02970
uniprot id: A1VJU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

365044:PNAP RS05400
gene id: 365044:PNAP_RS05400
uniprot id: A1VL72
names: Function
names: Similarity
messages: Belongs to the nucleoside phosphorylase PpnP family.
messages: Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions.

365044:PNAP RS14515
gene id: 365044:PNAP_RS14515
uniprot id: A1VRC8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.

365044:PNAP RS03255
gene id: 365044:PNAP_RS03255
uniprot id: A1VJZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

365044:PNAP RS10765
gene id: 365044:PNAP_RS10765
uniprot id: A1VP76
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.

365044:PNAP RS10310
gene id: 365044:PNAP_RS10310
uniprot id: A1VNY5
names: Subcellular Location Annotation
messages: Membrane

365044:PNAP RS13950
gene id: 365044:PNAP_RS13950
uniprot id: A1VR17
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.
messages: Cytoplasm

365044:PNAP RS18750
gene id: 365044:PNAP_RS18750
uniprot id: A1VTR9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

365044:PNAP RS08860
gene id: 365044:PNAP_RS08860
uniprot id: A1VN52
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
messages: Cytoplasm
messages: Homotrimer.
messages: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

365044:PNAP RS17975
gene id: 365044:PNAP_RS17975
uniprot id: A1VTC0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpC family.
messages: Cell inner membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

365044:PNAP RS02430
gene id: 365044:PNAP_RS02430
uniprot id: A1VJI2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

365044:PNAP RS22485
gene id: 365044:PNAP_RS22485
uniprot id: A1VVX0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

365044:PNAP RS18935
gene id: 365044:PNAP_RS18935
uniprot id: A1VTV7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

365044:PNAP RS07100
gene id: 365044:PNAP_RS07100
uniprot id: A1VM59
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

365044:PNAP RS20455
gene id: 365044:PNAP_RS20455
uniprot id: A1VUR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Membrane

365044:PNAP RS13415
gene id: 365044:PNAP_RS13415
uniprot id: A1VQR0
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

365044:PNAP RS10660
gene id: 365044:PNAP_RS10660
uniprot id: A1VP56
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

365044:PNAP RS12875
gene id: 365044:PNAP_RS12875
uniprot id: A1VQF1
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily.
messages: Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA.

365044:PNAP RS18800
gene id: 365044:PNAP_RS18800
uniprot id: A1VTS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
messages: Cell membrane
messages: Membrane

365044:PNAP RS00830
gene id: 365044:PNAP_RS00830
uniprot id: A1VIL7
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

365044:PNAP RS09360
gene id: 365044:PNAP_RS09360
uniprot id: A1VNF1
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.

365044:PNAP RS17820
gene id: 365044:PNAP_RS17820
uniprot id: A1VT89
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Homodimer.
messages: Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.

365044:PNAP RS11175
gene id: 365044:PNAP_RS11175
uniprot id: A1VPG0
names: Similarity
messages: Belongs to the threonine synthase family.

365044:PNAP RS16355
gene id: 365044:PNAP_RS16355
uniprot id: A1VSE9
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

365044:PNAP RS20565
gene id: 365044:PNAP_RS20565
uniprot id: A1VUT9
names: Similarity
messages: Belongs to the HipA Ser/Thr kinase family.

365044:PNAP RS06000
gene id: 365044:PNAP_RS06000
uniprot id: A1VLI5
names: Subcellular Location Annotation
messages: Membrane

365044:PNAP RS20680
gene id: 365044:PNAP_RS20680
uniprot id: A1VUW0
names: Similarity
messages: Belongs to the bacterial ring-hydroxylating dioxygenase beta subunit family.

365044:PNAP RS12680
gene id: 365044:PNAP_RS12680
uniprot id: A1VQB2
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

365044:PNAP RS04790
gene id: 365044:PNAP_RS04790
uniprot id: A1VKU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

365044:PNAP RS08355
gene id: 365044:PNAP_RS08355
uniprot id: A1VMV6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

365044:PNAP RS18510
gene id: 365044:PNAP_RS18510
uniprot id: A1VTM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbA subfamily.
messages: Periplasm

365044:PNAP RS14280
gene id: 365044:PNAP_RS14280
uniprot id: A1VR81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

365044:PNAP RS12095
gene id: 365044:PNAP_RS12095
uniprot id: A1VPZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

365044:PNAP RS06795
gene id: 365044:PNAP_RS06795
uniprot id: A1VLZ6
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

365044:PNAP RS01700
gene id: 365044:PNAP_RS01700
uniprot id: A1VJ40
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

365044:PNAP RS07805
gene id: 365044:PNAP_RS07805
uniprot id: A1VMJ9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

365044:PNAP RS12265
gene id: 365044:PNAP_RS12265
uniprot id: A1VQ30
names: Similarity
messages: Belongs to the GST superfamily. Zeta family.

365044:PNAP RS17900
gene id: 365044:PNAP_RS17900
uniprot id: A1VTA5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Molecular chaperone. Has ATPase activity.

365044:PNAP RS24155
gene id: 365044:PNAP_RS24155
uniprot id: A1VWV1
names: Similarity
messages: Belongs to the universal stress protein A family.

365044:PNAP RS09640
gene id: 365044:PNAP_RS09640
uniprot id: A1VNK5
names: Function
names: Similarity
messages: Belongs to the LpxK family.
messages: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

365044:PNAP RS14300
gene id: 365044:PNAP_RS14300
uniprot id: A1VR85
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

365044:PNAP RS15090
gene id: 365044:PNAP_RS15090
uniprot id: A1VRN8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

365044:PNAP RS18655
gene id: 365044:PNAP_RS18655
uniprot id: A1VTP9
names: Function
names: Similarity
messages: Anion-transporting ATPase.
messages: Belongs to the arsA ATPase family.

365044:PNAP RS09500
gene id: 365044:PNAP_RS09500
uniprot id: A1VNH9
names: Cofactor
names: Similarity
messages: Belongs to the UPF0313 family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

365044:PNAP RS10675
gene id: 365044:PNAP_RS10675
uniprot id: A1VP59
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

365044:PNAP RS06135
gene id: 365044:PNAP_RS06135
uniprot id: A1VLL2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

365044:PNAP RS24065
gene id: 365044:PNAP_RS24065
uniprot id: A1VWT6
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

365044:PNAP RS15325
gene id: 365044:PNAP_RS15325
uniprot id: A1VRT5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell inner membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

365044:PNAP RS04070
gene id: 365044:PNAP_RS04070
uniprot id: A1VKF9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.

365044:PNAP RS09990
gene id: 365044:PNAP_RS09990
uniprot id: A1VNS4
names: Function
names: Similarity
messages: Belongs to the catalase family. HPII subfamily.
messages: Serves to protect cells from the toxic effects of hydrogen peroxide.

365044:PNAP RS09430
gene id: 365044:PNAP_RS09430
uniprot id: A1VNG5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

365044:PNAP RS12170
gene id: 365044:PNAP_RS12170
uniprot id: A1VQ11
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

365044:PNAP RS10175
gene id: 365044:PNAP_RS10175
uniprot id: A1VNW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

365044:PNAP RS10365
gene id: 365044:PNAP_RS10365
uniprot id: A1VNZ6
names: Similarity
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.

365044:PNAP RS15200
gene id: 365044:PNAP_RS15200
uniprot id: A1VRR0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

365044:PNAP RS19710
gene id: 365044:PNAP_RS19710
uniprot id: A1VUC1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 2 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

365044:PNAP RS18475
gene id: 365044:PNAP_RS18475
uniprot id: A1VTL4
names: Subcellular Location Annotation
messages: Membrane

365044:PNAP RS18190
gene id: 365044:PNAP_RS18190
uniprot id: A1VTG1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

365044:PNAP RS13970
gene id: 365044:PNAP_RS13970
uniprot id: A1VR21
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

365044:PNAP RS18180
gene id: 365044:PNAP_RS18180
uniprot id: A1VTF9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

365044:PNAP RS12765
gene id: 365044:PNAP_RS12765
uniprot id: A1VQC9
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

365044:PNAP RS17020
gene id: 365044:PNAP_RS17020
uniprot id: A1VSS7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 51 family.
messages: Cell inner membrane
messages: Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors.

365044:PNAP RS25260
gene id: 365044:PNAP_RS25260
uniprot id: A1VVR6
names: Similarity
messages: Belongs to the ParB family.

365044:PNAP RS08840
gene id: 365044:PNAP_RS08840
uniprot id: A1VN48
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamA family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

365044:PNAP RS01125
gene id: 365044:PNAP_RS01125
uniprot id: A1VIS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

365044:PNAP RS11010
gene id: 365044:PNAP_RS11010
uniprot id: A1VPC7
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family.
messages: Part of the 50S ribosomal subunit.

365044:PNAP RS17245
gene id: 365044:PNAP_RS17245
uniprot id: A1VSX2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

365044:PNAP RS08305
gene id: 365044:PNAP_RS08305
uniprot id: A1VMU7
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

365044:PNAP RS14870
gene id: 365044:PNAP_RS14870
uniprot id: A1VRJ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

365044:PNAP RS16725
gene id: 365044:PNAP_RS16725
uniprot id: A1VSL7
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

365044:PNAP RS20920
gene id: 365044:PNAP_RS20920
uniprot id: A1VV07
names: Similarity
messages: Belongs to the TrbG/VirB9 family.

365044:PNAP RS05325
gene id: 365044:PNAP_RS05325
uniprot id: A1VL57
names: Similarity
messages: Belongs to the peptidase M1 family.

365044:PNAP RS04015
gene id: 365044:PNAP_RS04015
uniprot id: A1VKE9
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family. GreB subfamily.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length.

365044:PNAP RS15960
gene id: 365044:PNAP_RS15960
uniprot id: A1VS69
names: Subcellular Location Annotation
messages: Membrane

365044:PNAP RS00105
gene id: 365044:PNAP_RS00105
uniprot id: A1VI67
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
messages: Homodimer.

365044:PNAP RS16670
gene id: 365044:PNAP_RS16670
uniprot id: A1VSK6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

365044:PNAP RS05550
gene id: 365044:PNAP_RS05550
uniprot id: A1VL97
names: Similarity
messages: Belongs to the phosphohexose mutase family.

365044:PNAP RS19295
gene id: 365044:PNAP_RS19295
uniprot id: A1VU29
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.

365044:PNAP RS03835
gene id: 365044:PNAP_RS03835
uniprot id: A1VKB4
names: Similarity
messages: Belongs to the glutaredoxin family. Monothiol subfamily.

365044:PNAP RS08600
gene id: 365044:PNAP_RS08600
uniprot id: A1VN06
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homotetramer.

365044:PNAP RS01695
gene id: 365044:PNAP_RS01695
uniprot id: A1VJ39
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

365044:PNAP RS20545
gene id: 365044:PNAP_RS20545
uniprot id: A1VUT4
names: Similarity
messages: Belongs to the site-specific recombinase resolvase family.

365044:PNAP RS11760
gene id: 365044:PNAP_RS11760
uniprot id: A1VPT0
names: Similarity
messages: Belongs to the ArsC family.

365044:PNAP RS11785
gene id: 365044:PNAP_RS11785
uniprot id: A1VPT5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

365044:PNAP RS14635
gene id: 365044:PNAP_RS14635
uniprot id: A1VRF3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

365044:PNAP RS05680
gene id: 365044:PNAP_RS05680
uniprot id: A1VLC2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

365044:PNAP RS09580
gene id: 365044:PNAP_RS09580
uniprot id: A1VNJ3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

365044:PNAP RS15210
gene id: 365044:PNAP_RS15210
uniprot id: A1VRR2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

365044:PNAP RS04205
gene id: 365044:PNAP_RS04205
uniprot id: A1VKI5
names: Subcellular Location Annotation
messages: Membrane

365044:PNAP RS12015
gene id: 365044:PNAP_RS12015
uniprot id: A1VPY0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

365044:PNAP RS03325
gene id: 365044:PNAP_RS03325
uniprot id: A1VK12
names: Similarity
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.
messages: Membrane

365044:PNAP RS09340
gene id: 365044:PNAP_RS09340
uniprot id: A1VNE7
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

365044:PNAP RS05595
gene id: 365044:PNAP_RS05595
uniprot id: A1VLA5
names: Similarity
messages: Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.

365044:PNAP RS11155
gene id: 365044:PNAP_RS11155
uniprot id: A1VPF6
names: Similarity
names: Subunit
messages: Belongs to the MoaE family.
messages: Heterotetramer of 2 MoaD subunits and 2 MoaE subunits. Also stable as homodimer. The enzyme changes between these two forms during catalysis.

365044:PNAP RS14260
gene id: 365044:PNAP_RS14260
uniprot id: A1VR77
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged L-seryl-tRNA(Thr).
messages: Cytoplasm
messages: Homodimer.

365044:PNAP RS07880
gene id: 365044:PNAP_RS07880
uniprot id: A1VML5
names: Similarity
messages: Belongs to the NifZ family.

365044:PNAP RS07570
gene id: 365044:PNAP_RS07570
uniprot id: A1VMF2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell inner membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

365044:PNAP RS11460
gene id: 365044:PNAP_RS11460
uniprot id: A1VPL9
names: Function
names: Similarity
messages: A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.
messages: Belongs to the NifU family.

365044:PNAP RS15845
gene id: 365044:PNAP_RS15845
uniprot id: A1VS40
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

365044:PNAP RS19590
gene id: 365044:PNAP_RS19590
uniprot id: A1VU88
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

365044:PNAP RS12965
gene id: 365044:PNAP_RS12965
uniprot id: A1VQG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

365044:PNAP RS15070
gene id: 365044:PNAP_RS15070
uniprot id: A1VRN4
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

365044:PNAP RS01655
gene id: 365044:PNAP_RS01655
uniprot id: A1VJ30
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

365044:PNAP RS24445
gene id: 365044:PNAP_RS24445
uniprot id: A1VX09
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

365044:PNAP RS18175
gene id: 365044:PNAP_RS18175
uniprot id: A1VTF8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

365044:PNAP RS16960
gene id: 365044:PNAP_RS16960
uniprot id: A1VSR4
names: Function
names: Similarity
messages: Belongs to the MurCDEF family. Mpl subfamily.
messages: Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl-meso-diaminopimelate by linking it to UDP-N-acetylmuramate.

365044:PNAP RS05015
gene id: 365044:PNAP_RS05015
uniprot id: A1VKZ6
names: Subcellular Location Annotation
messages: Membrane

365044:PNAP RS11580
gene id: 365044:PNAP_RS11580
uniprot id: A1VPP5
names: Function
names: Similarity
messages: Belongs to the ETF-QO/FixC family.
messages: Part of an electron transfer system.

365044:PNAP RS14000
gene id: 365044:PNAP_RS14000
uniprot id: A1VR27
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

365044:PNAP RS06385
gene id: 365044:PNAP_RS06385
uniprot id: A1VLR2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

365044:PNAP RS17705
gene id: 365044:PNAP_RS17705
uniprot id: A1VT66
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

365044:PNAP RS05030
gene id: 365044:PNAP_RS05030
uniprot id: A1VKZ9
names: Similarity
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the malic enzymes family.

365044:PNAP RS15300
gene id: 365044:PNAP_RS15300
uniprot id: A1VRT0
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

365044:PNAP RS13365
gene id: 365044:PNAP_RS13365
uniprot id: A1VQQ0
names: Similarity
messages: Belongs to the thiolase-like superfamily. Chalcone/stilbene synthases family.

365044:PNAP RS18170
gene id: 365044:PNAP_RS18170
uniprot id: A1VTF7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

365044:PNAP RS12140
gene id: 365044:PNAP_RS12140
uniprot id: A1VQ05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

365044:PNAP RS03285
gene id: 365044:PNAP_RS03285
uniprot id: A1VK04
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

365044:PNAP RS15105
gene id: 365044:PNAP_RS15105
uniprot id: A1VRP1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tryptophan 2,3-dioxygenase family.
messages: Binds 1 heme group per subunit.
messages: Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L-tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.
messages: Homotetramer.

365044:PNAP RS18390
gene id: 365044:PNAP_RS18390
uniprot id: A1VTJ7
names: Similarity
messages: Belongs to the leucine-binding protein family.

365044:PNAP RS02345
gene id: 365044:PNAP_RS02345
uniprot id: A1VJG7
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

365044:PNAP RS14315
gene id: 365044:PNAP_RS14315
uniprot id: A1VR88
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

365044:PNAP RS15650
gene id: 365044:PNAP_RS15650
uniprot id: A1VS00
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

365044:PNAP RS04620
gene id: 365044:PNAP_RS04620
uniprot id: A1VKR6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Homodimer.

365044:PNAP RS06780
gene id: 365044:PNAP_RS06780
uniprot id: A1VLZ3
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell inner membrane

365044:PNAP RS03240
gene id: 365044:PNAP_RS03240
uniprot id: A1VJZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transaldolase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

365044:PNAP RS05520
gene id: 365044:PNAP_RS05520
uniprot id: A1VL91
names: Similarity
messages: Belongs to the disproportionating enzyme family.

365044:PNAP RS12155
gene id: 365044:PNAP_RS12155
uniprot id: A1VQ08
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
messages: Cytoplasm

365044:PNAP RS00980
gene id: 365044:PNAP_RS00980
uniprot id: A1VIP7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

365044:PNAP RS04235
gene id: 365044:PNAP_RS04235
uniprot id: A1VKJ1
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

365044:PNAP RS10635
gene id: 365044:PNAP_RS10635
uniprot id: A1VP51
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

365044:PNAP RS10445
gene id: 365044:PNAP_RS10445
uniprot id: A1VP12
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

365044:PNAP RS10435
gene id: 365044:PNAP_RS10435
uniprot id: A1VP10
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

365044:PNAP RS11540
gene id: 365044:PNAP_RS11540
uniprot id: A1VPN7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

365044:PNAP RS08930
gene id: 365044:PNAP_RS08930
uniprot id: A1VN66
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

365044:PNAP RS19880
gene id: 365044:PNAP_RS19880
uniprot id: A1VUF6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

365044:PNAP RS06510
gene id: 365044:PNAP_RS06510
uniprot id: A1VLT6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

365044:PNAP RS10280
gene id: 365044:PNAP_RS10280
uniprot id: A1VNX9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpoB family.
messages: Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division.
messages: Periplasm

365044:PNAP RS01195
gene id: 365044:PNAP_RS01195
uniprot id: A1VIU0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

365044:PNAP RS17145
gene id: 365044:PNAP_RS17145
uniprot id: A1VSV2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

365044:PNAP RS06515
gene id: 365044:PNAP_RS06515
uniprot id: A1VLT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

365044:PNAP RS01580
gene id: 365044:PNAP_RS01580
uniprot id: A1VJ15
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

365044:PNAP RS14365
gene id: 365044:PNAP_RS14365
uniprot id: A1VR98
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.

365044:PNAP RS15695
gene id: 365044:PNAP_RS15695
uniprot id: A1VS09
names: Similarity
messages: Belongs to the PspA/IM30 family.

365044:PNAP RS11200
gene id: 365044:PNAP_RS11200
uniprot id: A1VPG5
names: Similarity
messages: Belongs to the PhoH family.

365044:PNAP RS13820
gene id: 365044:PNAP_RS13820
uniprot id: A1VQZ1
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

365044:PNAP RS01615
gene id: 365044:PNAP_RS01615
uniprot id: A1VJ22
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

365044:PNAP RS16915
gene id: 365044:PNAP_RS16915
uniprot id: A1VSQ5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

365044:PNAP RS07855
gene id: 365044:PNAP_RS07855
uniprot id: A1VML0
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. NifB family.
messages: Involved in the biosynthesis of the iron-molybdenum cofactor (FeMo-co or M-cluster) found in the dinitrogenase enzyme of the nitrogenase complex in nitrogen-fixing microorganisms. NifB catalyzes the crucial step of radical SAM-dependent carbide insertion that occurs concomitant with the insertion of a 9th sulfur and the rearrangement/coupling of two [4Fe-4S] clusters into a [8Fe-9S-C] cluster, the precursor to the M-cluster.

365044:PNAP RS17465
gene id: 365044:PNAP_RS17465
uniprot id: A1VT17
names: Subcellular Location Annotation
messages: Membrane

365044:PNAP RS13055
gene id: 365044:PNAP_RS13055
uniprot id: A1VQI8
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

365044:PNAP RS09355
gene id: 365044:PNAP_RS09355
uniprot id: A1VNF0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

365044:PNAP RS16035
gene id: 365044:PNAP_RS16035
uniprot id: A1VS84
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

365044:PNAP RS03985
gene id: 365044:PNAP_RS03985
uniprot id: A1VKE3
names: Subcellular Location Annotation
messages: Membrane

365044:PNAP RS15435
gene id: 365044:PNAP_RS15435
uniprot id: A1VRV7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase E/G family. RNase E subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per homotetramer.
messages: Cell inner membrane
messages: Cytoplasm
messages: Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs.
messages: Homotetramer formed by a dimer of dimers.

365044:PNAP RS18465
gene id: 365044:PNAP_RS18465
uniprot id: A1VTL2
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

365044:PNAP RS01970
gene id: 365044:PNAP_RS01970
uniprot id: A1VJ95
names: Similarity
messages: Belongs to the PhzF family.

365044:PNAP RS22910
gene id: 365044:PNAP_RS22910
uniprot id: A1VW53
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

365044:PNAP RS07160
gene id: 365044:PNAP_RS07160
uniprot id: A1VM70
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell inner membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

365044:PNAP RS04900
gene id: 365044:PNAP_RS04900
uniprot id: A1VKX1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Cell inner membrane
messages: Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate from the periplasm across the membrane.

365044:PNAP RS22455
gene id: 365044:PNAP_RS22455
uniprot id: A1VVW4
names: Subcellular Location Annotation
messages: Membrane

365044:PNAP RS10735
gene id: 365044:PNAP_RS10735
uniprot id: A1VP70
names: Similarity
messages: Belongs to the PrpD family.

365044:PNAP RS12160
gene id: 365044:PNAP_RS12160
uniprot id: A1VQ09
names: Similarity
messages: Belongs to the PAPS reductase family. CysD subfamily.

365044:PNAP RS06410
gene id: 365044:PNAP_RS06410
uniprot id: A1VLR7
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

365044:PNAP RS08475
gene id: 365044:PNAP_RS08475
uniprot id: A1VMY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

365044:PNAP RS00880
gene id: 365044:PNAP_RS00880
uniprot id: A1VIM7
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

365044:PNAP RS15975
gene id: 365044:PNAP_RS15975
uniprot id: A1VS72
names: Similarity
messages: Belongs to the DEAD box helicase family.

365044:PNAP RS04485
gene id: 365044:PNAP_RS04485
uniprot id: A1VKP0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LolB family.
messages: Cell outer membrane
messages: Membrane
messages: Monomer.

365044:PNAP RS11970
gene id: 365044:PNAP_RS11970
uniprot id: A1VPX2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

365044:PNAP RS00975
gene id: 365044:PNAP_RS00975
uniprot id: A1VIP6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

365044:PNAP RS09845
gene id: 365044:PNAP_RS09845
uniprot id: A1VNP5
names: Function
names: Similarity
messages: Belongs to the HypA/HybF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.

365044:PNAP RS12120
gene id: 365044:PNAP_RS12120
uniprot id: A1VQ01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic sulfate-binding protein family.
messages: Periplasm

365044:PNAP RS22565
gene id: 365044:PNAP_RS22565
uniprot id: A1VVY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

365044:PNAP RS07725
gene id: 365044:PNAP_RS07725
uniprot id: A1VMI3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsbB family.
messages: Cell inner membrane
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein.

365044:PNAP RS12925
gene id: 365044:PNAP_RS12925
uniprot id: A1VQG1
names: Similarity
messages: Belongs to the ArsC family.

365044:PNAP RS10885
gene id: 365044:PNAP_RS10885
uniprot id: A1VPA0
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

365044:PNAP RS09915
gene id: 365044:PNAP_RS09915
uniprot id: A1VNQ9
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the RuBisCO large chain family. Type II subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site.
messages: The basic functional RuBisCO is composed of a large chain homodimer in a 'head-to-tail' conformation. In contrast to form I RuBisCO, the form II RuBisCO are composed solely of large subunits.

365044:PNAP RS15355
gene id: 365044:PNAP_RS15355
uniprot id: A1VRU1
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

365044:PNAP RS17645
gene id: 365044:PNAP_RS17645
uniprot id: A1VT54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

365044:PNAP RS01910
gene id: 365044:PNAP_RS01910
uniprot id: A1VJ84
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

365044:PNAP RS01870
gene id: 365044:PNAP_RS01870
uniprot id: A1VJ74
names: Similarity
messages: Belongs to the UPF0235 family.

365044:PNAP RS14430
gene id: 365044:PNAP_RS14430
uniprot id: A1VRB0
names: Similarity
messages: Belongs to the aspartokinase family.

365044:PNAP RS08250
gene id: 365044:PNAP_RS08250
uniprot id: A1VMT6
names: Similarity
messages: Belongs to the leucine-binding protein family.

365044:PNAP RS02985
gene id: 365044:PNAP_RS02985
uniprot id: A1VJU3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

365044:PNAP RS15720
gene id: 365044:PNAP_RS15720
uniprot id: Q3S4B7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 3-hydroxybenzoate 6-hydroxylase family.
messages: Catalyzes the NAD- or NADP-dependent conversion of 3-hydroxybenzoate to gentisate. The affinity of the enzyme toward NAD is twice as high as for NADP.
messages: Monomer.

365044:PNAP RS18235
gene id: 365044:PNAP_RS18235
uniprot id: A1VTG6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

365044:PNAP RS00590
gene id: 365044:PNAP_RS00590
uniprot id: A1VIG6
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

365044:PNAP RS05005
gene id: 365044:PNAP_RS05005
uniprot id: A1VKZ4
names: Function
names: Similarity
names: Subunit
messages: Catalyzes the ATP-dependent polymerization of arginine and aspartate to multi-L-arginyl-poly-L-aspartic acid (cyanophycin; a water-insoluble reserve polymer).
messages: Homodimer.
messages: In the C-terminal section; belongs to the MurCDEF family.

365044:PNAP RS15240
gene id: 365044:PNAP_RS15240
uniprot id: A1VRR8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

365044:PNAP RS10080
gene id: 365044:PNAP_RS10080
uniprot id: A1VNU2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

365044:PNAP RS19985
gene id: 365044:PNAP_RS19985
uniprot id: A1VUH6
names: Subcellular Location Annotation
messages: Membrane

365044:PNAP RS04190
gene id: 365044:PNAP_RS04190
uniprot id: A1VKI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

365044:PNAP RS17850
gene id: 365044:PNAP_RS17850
uniprot id: A1VT95
names: Similarity
messages: Belongs to the leucine-binding protein family.

365044:PNAP RS14350
gene id: 365044:PNAP_RS14350
uniprot id: A1VR95
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell inner membrane

365044:PNAP RS18900
gene id: 365044:PNAP_RS18900
uniprot id: A1VTV0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Binds 1 copper ion per subunit, denoted as copper B.
messages: Binds 2 heme groups per subunit, denoted as high- and low-spin.
messages: Membrane

365044:PNAP RS20345
gene id: 365044:PNAP_RS20345
uniprot id: A1VUP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

365044:PNAP RS10825
gene id: 365044:PNAP_RS10825
uniprot id: A1VP88
names: Function
names: Similarity
names: Subunit
messages: Belongs to the precorrin methyltransferase family.
messages: Homodimer.
messages: Methylates precorrin-2 at the C-20 position to produce precorrin-3A.

365044:PNAP RS04870
gene id: 365044:PNAP_RS04870
uniprot id: A1VKW4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease beta subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

365044:PNAP RS18490
gene id: 365044:PNAP_RS18490
uniprot id: A1VTL7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

365044:PNAP RS20200
gene id: 365044:PNAP_RS20200
uniprot id: A1VUL5
names: Subcellular Location Annotation
messages: Membrane

365044:PNAP RS00215
gene id: 365044:PNAP_RS00215
uniprot id: A1VI89
names: Subcellular Location Annotation
messages: Periplasm

365044:PNAP RS14700
gene id: 365044:PNAP_RS14700
uniprot id: A1VRG6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

365044:PNAP RS17495
gene id: 365044:PNAP_RS17495
uniprot id: A1VT23
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

365044:PNAP RS24295
gene id: 365044:PNAP_RS24295
uniprot id: A1VWX8
names: Subcellular Location Annotation
messages: Membrane

365044:PNAP RS11840
gene id: 365044:PNAP_RS11840
uniprot id: A1VPU6
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.

365044:PNAP RS13410
gene id: 365044:PNAP_RS13410
uniprot id: A1VQQ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

365044:PNAP RS12125
gene id: 365044:PNAP_RS12125
uniprot id: A1VQ02
names: Function
names: Similarity
messages: Belongs to the Fe(2+)-trafficking protein family.
messages: Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.

365044:PNAP RS09350
gene id: 365044:PNAP_RS09350
uniprot id: A1VNE9
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

365044:PNAP RS24285
gene id: 365044:PNAP_RS24285
uniprot id: A1VWX6
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. Nitrilase family.

365044:PNAP RS21450
gene id: 365044:PNAP_RS21450
uniprot id: A1VVB9
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

365044:PNAP RS13460
gene id: 365044:PNAP_RS13460
uniprot id: A1VQR9
names: Similarity
messages: Belongs to the xanthine dehydrogenase family.

365044:PNAP RS19515
gene id: 365044:PNAP_RS19515
uniprot id: A1VU73
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

365044:PNAP RS05885
gene id: 365044:PNAP_RS05885
uniprot id: A1VLG2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

365044:PNAP RS07245
gene id: 365044:PNAP_RS07245
uniprot id: A1VM87
names: Similarity
messages: Belongs to the CFA/CMAS family.

365044:PNAP RS17025
gene id: 365044:PNAP_RS17025
uniprot id: A1VSS8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RuvC family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.