362837:SCANT RS00085
gene id: 362837:SCANT_RS00085
uniprot id: A0A0M4KBH6
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

362837:SCANT RS05140
gene id: 362837:SCANT_RS05140
uniprot id: A0A0M4JT93
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.

362837:SCANT RS00490
gene id: 362837:SCANT_RS00490
uniprot id: A0A0M3SJ26
names: Subcellular Location Annotation
messages: Cytoplasm

362837:SCANT RS04145
gene id: 362837:SCANT_RS04145
uniprot id: A0A0M4K200
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

362837:SCANT RS01710
gene id: 362837:SCANT_RS01710
uniprot id: A0A0M4JRZ9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

362837:SCANT RS00025
gene id: 362837:SCANT_RS00025
uniprot id: A0A0M4KBG8
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

362837:SCANT RS02480
gene id: 362837:SCANT_RS02480
uniprot id: A0A0M4JJK1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 2 subfamily.
messages: Cell membrane
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

362837:SCANT RS01585
gene id: 362837:SCANT_RS01585
uniprot id: A0A0M4JRY2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
messages: Homodimer.

362837:SCANT RS05120
gene id: 362837:SCANT_RS05120
uniprot id: A0A0M4JXN0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

362837:SCANT RS04640
gene id: 362837:SCANT_RS04640
uniprot id: A0A0M4KFC4
names: Subcellular Location Annotation
messages: Membrane

362837:SCANT RS02945
gene id: 362837:SCANT_RS02945
uniprot id: A0A0M4JIL8
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

362837:SCANT RS04770
gene id: 362837:SCANT_RS04770
uniprot id: A0A0M3SJJ3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

362837:SCANT RS04965
gene id: 362837:SCANT_RS04965
uniprot id: A0A0M4JKH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

362837:SCANT RS00575
gene id: 362837:SCANT_RS00575
uniprot id: A0A0M4K0M9
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

362837:SCANT RS04160
gene id: 362837:SCANT_RS04160
uniprot id: A0A0M4KD08
names: Subcellular Location Annotation
messages: Membrane

362837:SCANT RS02535
gene id: 362837:SCANT_RS02535
uniprot id: A0A0M4JSA3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

362837:SCANT RS00150
gene id: 362837:SCANT_RS00150
uniprot id: A0A0M4KBI7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

362837:SCANT RS04885
gene id: 362837:SCANT_RS04885
uniprot id: A0A0M4KFF4
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

362837:SCANT RS00950
gene id: 362837:SCANT_RS00950
uniprot id: A0A0M4JS19
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.
messages: Cytoplasm
messages: Homodimer.

362837:SCANT RS01030
gene id: 362837:SCANT_RS01030
uniprot id: A0A0M4JJ20
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

362837:SCANT RS00960
gene id: 362837:SCANT_RS00960
uniprot id: A0A0M4JRQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

362837:SCANT RS03905
gene id: 362837:SCANT_RS03905
uniprot id: A0A0M4JIZ0
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

362837:SCANT RS04655
gene id: 362837:SCANT_RS04655
uniprot id: A0A0M4JT32
names: Similarity
messages: Belongs to the LacAB/RpiB family.

362837:SCANT RS02735
gene id: 362837:SCANT_RS02735
uniprot id: A0A0M4K1G1
names: Similarity
messages: Belongs to the TlyA family.

362837:SCANT RS00240
gene id: 362837:SCANT_RS00240
uniprot id: A0A0M3SJ16
names: Similarity
messages: Belongs to the LacAB/RpiB family.

362837:SCANT RS04430
gene id: 362837:SCANT_RS04430
uniprot id: A0A0M3SJH6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThiI family.
messages: Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
messages: Cytoplasm

362837:SCANT RS04380
gene id: 362837:SCANT_RS04380
uniprot id: A0A0M3SJH4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

362837:SCANT RS04410
gene id: 362837:SCANT_RS04410
uniprot id: A0A0M3SJH9
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.

362837:SCANT RS00390
gene id: 362837:SCANT_RS00390
uniprot id: A0A0M3SJ22
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

362837:SCANT RS02990
gene id: 362837:SCANT_RS02990
uniprot id: A0A0M3SJC0
names: Subcellular Location Annotation
messages: Membrane

362837:SCANT RS04880
gene id: 362837:SCANT_RS04880
uniprot id: A0A0M5KCJ8
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

362837:SCANT RS00165
gene id: 362837:SCANT_RS00165
uniprot id: A0A0M5KJ00
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

362837:SCANT RS03330
gene id: 362837:SCANT_RS03330
uniprot id: A0A0M4KET2
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

362837:SCANT RS04025
gene id: 362837:SCANT_RS04025
uniprot id: A0A0M4JJ07
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

362837:SCANT RS00715
gene id: 362837:SCANT_RS00715
uniprot id: A0A0M3SJ34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

362837:SCANT RS01720
gene id: 362837:SCANT_RS01720
uniprot id: A0A0M4K123
names: Similarity
messages: Belongs to the ABC transporter superfamily.

362837:SCANT RS00680
gene id: 362837:SCANT_RS00680
uniprot id: A0A0M4KBQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

362837:SCANT RS02825
gene id: 362837:SCANT_RS02825
uniprot id: A0A0M4JWS5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

362837:SCANT RS02920
gene id: 362837:SCANT_RS02920
uniprot id: A0A0M3SJC1
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

362837:SCANT RS00275
gene id: 362837:SCANT_RS00275
uniprot id: A0A0M4KBK2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

362837:SCANT RS05125
gene id: 362837:SCANT_RS05125
uniprot id: A0A0M5KCR2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

362837:SCANT RS02020
gene id: 362837:SCANT_RS02020
uniprot id: A0A0M4JS40
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

362837:SCANT RS04915
gene id: 362837:SCANT_RS04915
uniprot id: A0A0M5KCI2
names: Similarity
messages: Belongs to the peptidase M17 family.

362837:SCANT RS03695
gene id: 362837:SCANT_RS03695
uniprot id: A0A0M4JIW6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm
messages: Homodimer.

362837:SCANT RS04660
gene id: 362837:SCANT_RS04660
uniprot id: A0A0M4JKD6
names: Similarity
messages: Belongs to the LacAB/RpiB family.

362837:SCANT RS03185
gene id: 362837:SCANT_RS03185
uniprot id: A0A0M4KCP0
names: Subcellular Location Annotation
messages: Membrane

362837:SCANT RS03370
gene id: 362837:SCANT_RS03370
uniprot id: A0A0M4KCR4
names: Subcellular Location Annotation
messages: Membrane

362837:SCANT RS02015
gene id: 362837:SCANT_RS02015
uniprot id: A0A0M4JSF1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

362837:SCANT RS02005
gene id: 362837:SCANT_RS02005
uniprot id: A0A0M3SJ85
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

362837:SCANT RS04440
gene id: 362837:SCANT_RS04440
uniprot id: A0A0M4KF75
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

362837:SCANT RS03120
gene id: 362837:SCANT_RS03120
uniprot id: A0A0M3SJC9
names: Subcellular Location Annotation
messages: Membrane

362837:SCANT RS04530
gene id: 362837:SCANT_RS04530
uniprot id: A0A0M4JKB5
names: Similarity
messages: Belongs to the Fur family.

362837:SCANT RS04185
gene id: 362837:SCANT_RS04185
uniprot id: A0A0M4KF39
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmG family. TrmFO subfamily.
messages: Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
messages: Cytoplasm

362837:SCANT RS05210
gene id: 362837:SCANT_RS05210
uniprot id: A0A0M4JKK3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

362837:SCANT RS00780
gene id: 362837:SCANT_RS00780
uniprot id: A0A0M4K0P5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

362837:SCANT RS03560
gene id: 362837:SCANT_RS03560
uniprot id: A0A0M4JIV1
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

362837:SCANT RS05060
gene id: 362837:SCANT_RS05060
uniprot id: A0A0M5KCL4
names: Similarity
messages: Belongs to the IspF family.

362837:SCANT RS03860
gene id: 362837:SCANT_RS03860
uniprot id: A0A0M4KEZ8
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Homodimer.

362837:SCANT RS03040
gene id: 362837:SCANT_RS03040
uniprot id: A0A0M3SJC2
names: Subcellular Location Annotation
messages: Membrane

362837:SCANT RS02710
gene id: 362837:SCANT_RS02710
uniprot id: A0A0M4KEJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

362837:SCANT RS04355
gene id: 362837:SCANT_RS04355
uniprot id: A0A0M4JJ48
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

362837:SCANT RS05155
gene id: 362837:SCANT_RS05155
uniprot id: A0A0M5KH54
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

362837:SCANT RS00925
gene id: 362837:SCANT_RS00925
uniprot id: A0A0M4JHX6
names: Subcellular Location Annotation
messages: Membrane

362837:SCANT RS02905
gene id: 362837:SCANT_RS02905
uniprot id: A0A0M4JSR6
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

362837:SCANT RS01865
gene id: 362837:SCANT_RS01865
uniprot id: A0A0M4JI88
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

362837:SCANT RS00775
gene id: 362837:SCANT_RS00775
uniprot id: A0A0M4JIZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIB subfamily.
messages: Cell inner membrane
messages: Mediates magnesium influx to the cytosol.

362837:SCANT RS03765
gene id: 362837:SCANT_RS03765
uniprot id: A0A0M5KCH5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

362837:SCANT RS04815
gene id: 362837:SCANT_RS04815
uniprot id: A0A0M5KCQ5
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

362837:SCANT RS01405
gene id: 362837:SCANT_RS01405
uniprot id: A0A0M3SJ61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

362837:SCANT RS03005
gene id: 362837:SCANT_RS03005
uniprot id: A0A0M4JIM6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

362837:SCANT RS04820
gene id: 362837:SCANT_RS04820
uniprot id: A0A0M3SJJ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

362837:SCANT RS01650
gene id: 362837:SCANT_RS01650
uniprot id: A0A0M4JJ98
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

362837:SCANT RS01640
gene id: 362837:SCANT_RS01640
uniprot id: A0A0M4JSA4
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

362837:SCANT RS03915
gene id: 362837:SCANT_RS03915
uniprot id: A0A0M3SJF6
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

362837:SCANT RS04940
gene id: 362837:SCANT_RS04940
uniprot id: A0A0M3SJJ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

362837:SCANT RS04760
gene id: 362837:SCANT_RS04760
uniprot id: A0A0M4KFE0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

362837:SCANT RS00485
gene id: 362837:SCANT_RS00485
uniprot id: A0A0M4KDU5
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

362837:SCANT RS00640
gene id: 362837:SCANT_RS00640
uniprot id: A0A0M3SJ32
names: Similarity
messages: Belongs to the ABC transporter superfamily.

362837:SCANT RS03690
gene id: 362837:SCANT_RS03690
uniprot id: A0A0M3SJE8
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

362837:SCANT RS02275
gene id: 362837:SCANT_RS02275
uniprot id: A0A0M4JSI3
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

362837:SCANT RS03740
gene id: 362837:SCANT_RS03740
uniprot id: A0A0M3SJF0
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

362837:SCANT RS04600
gene id: 362837:SCANT_RS04600
uniprot id: A0A0M4JKC7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

362837:SCANT RS03975
gene id: 362837:SCANT_RS03975
uniprot id: A0A0M4JX80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

362837:SCANT RS01165
gene id: 362837:SCANT_RS01165
uniprot id: A0A0M5KED0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-3 family.
messages: Cytoplasm
messages: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
messages: Monomer.

362837:SCANT RS05160
gene id: 362837:SCANT_RS05160
uniprot id: A0A0M3SJK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm

362837:SCANT RS03890
gene id: 362837:SCANT_RS03890
uniprot id: A0A0M5KH18
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RNase HII family. RnhC subfamily.
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

362837:SCANT RS02685
gene id: 362837:SCANT_RS02685
uniprot id: A0A0M4KCI1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AP endonuclease 2 family.
messages: Binds 3 Zn(2+) ions.
messages: Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.

362837:SCANT RS03050
gene id: 362837:SCANT_RS03050
uniprot id: A0A0M4K1K5
names: Cofactor
messages: Binds 1 Mg(2+) ion per trimer.

362837:SCANT RS04325
gene id: 362837:SCANT_RS04325
uniprot id: A0A0M4JSY6
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

362837:SCANT RS00900
gene id: 362837:SCANT_RS00900
uniprot id: A0A0M3SJ39
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the ferredoxin--NADP reductase type 2 family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

362837:SCANT RS00380
gene id: 362837:SCANT_RS00380
uniprot id: A0A0M4JIV5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Membrane

362837:SCANT RS01120
gene id: 362837:SCANT_RS01120
uniprot id: A0A0M4JW53
names: Subcellular Location Annotation
messages: Membrane

362837:SCANT RS05220
gene id: 362837:SCANT_RS05220
uniprot id: A0A0M4K2D7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OXA1/ALB3/YidC family.
messages: Cell membrane
messages: Membrane

362837:SCANT RS00435
gene id: 362837:SCANT_RS00435
uniprot id: A0A0M4JRJ2
names: Subcellular Location Annotation
messages: Membrane

362837:SCANT RS00530
gene id: 362837:SCANT_RS00530
uniprot id: A0A0M4JHT2
names: Similarity
messages: Belongs to the ABC transporter superfamily.

362837:SCANT RS01465
gene id: 362837:SCANT_RS01465
uniprot id: A0A0M4JJ74
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

362837:SCANT RS00415
gene id: 362837:SCANT_RS00415
uniprot id: A0A0M5KE15
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

362837:SCANT RS02270
gene id: 362837:SCANT_RS02270
uniprot id: A0A0M4KEE5
names: Subcellular Location Annotation
messages: Membrane

362837:SCANT RS00190
gene id: 362837:SCANT_RS00190
uniprot id: A0A0M3SJ14
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

362837:SCANT RS00540
gene id: 362837:SCANT_RS00540
uniprot id: A0A0M3SJ28
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

362837:SCANT RS03130
gene id: 362837:SCANT_RS03130
uniprot id: A0A0M4JIP4
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

362837:SCANT RS05165
gene id: 362837:SCANT_RS05165
uniprot id: A0A0M4KDB2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

362837:SCANT RS04340
gene id: 362837:SCANT_RS04340
uniprot id: A0A0M4K224
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

362837:SCANT RS02225
gene id: 362837:SCANT_RS02225
uniprot id: A0A0M4JJG8
names: Subcellular Location Annotation
messages: Membrane

362837:SCANT RS04810
gene id: 362837:SCANT_RS04810
uniprot id: A0A0M4JXI8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

362837:SCANT RS04435
gene id: 362837:SCANT_RS04435
uniprot id: A0A0M5KCJ6
names: Subcellular Location Annotation
messages: Membrane

362837:SCANT RS01020
gene id: 362837:SCANT_RS01020
uniprot id: A0A0M4JRQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

362837:SCANT RS00385
gene id: 362837:SCANT_RS00385
uniprot id: A0A0M4K0K4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

362837:SCANT RS02460
gene id: 362837:SCANT_RS02460
uniprot id: A0A0M4KEG6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
messages: Belongs to the azoreductase type 1 family.
messages: Binds 1 FMN per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones.

362837:SCANT RS00140
gene id: 362837:SCANT_RS00140
uniprot id: A0A0M3SJ12
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

362837:SCANT RS01350
gene id: 362837:SCANT_RS01350
uniprot id: A0A0M5KGV1
names: Similarity
messages: Belongs to the peptidase M13 family.

362837:SCANT RS00600
gene id: 362837:SCANT_RS00600
uniprot id: A0A0M4JVZ7
names: Subcellular Location Annotation
messages: Membrane

362837:SCANT RS00065
gene id: 362837:SCANT_RS00065
uniprot id: A0A0M4JIR8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

362837:SCANT RS00020
gene id: 362837:SCANT_RS00020
uniprot id: A0A0M3SJ07
names: Similarity
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.

362837:SCANT RS03770
gene id: 362837:SCANT_RS03770
uniprot id: A0A0M3SJF5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. PolC subfamily.
messages: Cytoplasm
messages: Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

362837:SCANT RS03720
gene id: 362837:SCANT_RS03720
uniprot id: A0A0M3SJF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

362837:SCANT RS04010
gene id: 362837:SCANT_RS04010
uniprot id: A0A0M3SJG0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

362837:SCANT RS02960
gene id: 362837:SCANT_RS02960
uniprot id: A0A0M4KEN1
names: Subcellular Location Annotation
messages: Membrane

362837:SCANT RS05065
gene id: 362837:SCANT_RS05065
uniprot id: A0A0M3SJK5
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

362837:SCANT RS03410
gene id: 362837:SCANT_RS03410
uniprot id: A0A0M4JJX5
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

362837:SCANT RS03135
gene id: 362837:SCANT_RS03135
uniprot id: A0A0M4JWX0
names: Cofactor
messages: Binds 1 zinc ion per subunit.

362837:SCANT RS01080
gene id: 362837:SCANT_RS01080
uniprot id: A0A0M4JS34
names: Similarity
messages: Belongs to the ABC transporter superfamily.

362837:SCANT RS00690
gene id: 362837:SCANT_RS00690
uniprot id: A0A0M4JW05
names: Similarity
messages: Belongs to the thioredoxin family.

362837:SCANT RS01645
gene id: 362837:SCANT_RS01645
uniprot id: A0A0M4JRZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

362837:SCANT RS04405
gene id: 362837:SCANT_RS04405
uniprot id: A0A0M5KLR8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

362837:SCANT RS02890
gene id: 362837:SCANT_RS02890
uniprot id: A0A0M3SJB6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

362837:SCANT RS01085
gene id: 362837:SCANT_RS01085
uniprot id: A0A0M4JRS0
names: Cofactor
messages: Binds 1 Mg(2+) ion per trimer.

362837:SCANT RS01980
gene id: 362837:SCANT_RS01980
uniprot id: A0A0M3SJ80
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

362837:SCANT RS03115
gene id: 362837:SCANT_RS03115
uniprot id: A0A0M5KLM8
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

362837:SCANT RS02490
gene id: 362837:SCANT_RS02490
uniprot id: A0A0M3SJA0
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

362837:SCANT RS01160
gene id: 362837:SCANT_RS01160
uniprot id: A0A0M4K0V0
names: Similarity
messages: Belongs to the RutC family.

362837:SCANT RS02465
gene id: 362837:SCANT_RS02465
uniprot id: A0A0M4JSK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uridine kinase family.
messages: Cytoplasm

362837:SCANT RS04080
gene id: 362837:SCANT_RS04080
uniprot id: A0A0M4JK56
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

362837:SCANT RS04285
gene id: 362837:SCANT_RS04285
uniprot id: A0A0M4KD22
names: Similarity
messages: Belongs to the asp23 family.

362837:SCANT RS00125
gene id: 362837:SCANT_RS00125
uniprot id: A0A0M4JRF1
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

362837:SCANT RS04870
gene id: 362837:SCANT_RS04870
uniprot id: A0A0M3SJJ7
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

362837:SCANT RS00475
gene id: 362837:SCANT_RS00475
uniprot id: A0A0M4JVY5
names: Subcellular Location Annotation
messages: Membrane

362837:SCANT RS04830
gene id: 362837:SCANT_RS04830
uniprot id: A0A0M4JTH7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

362837:SCANT RS02895
gene id: 362837:SCANT_RS02895
uniprot id: A0A0M5KCK8
names: Subcellular Location Annotation
messages: Membrane

362837:SCANT RS00270
gene id: 362837:SCANT_RS00270
uniprot id: A0A0M3SJ17
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

362837:SCANT RS01685
gene id: 362837:SCANT_RS01685
uniprot id: A0A0M4JWC9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

362837:SCANT RS01835
gene id: 362837:SCANT_RS01835
uniprot id: A0A0M4JS16
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

362837:SCANT RS02615
gene id: 362837:SCANT_RS02615
uniprot id: A0A0M5KGY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0154 family.
messages: Membrane

362837:SCANT RS04250
gene id: 362837:SCANT_RS04250
uniprot id: A0A0M4JT92
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

362837:SCANT RS02800
gene id: 362837:SCANT_RS02800
uniprot id: A0A0M4K1G9
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

362837:SCANT RS01355
gene id: 362837:SCANT_RS01355
uniprot id: A0A0M3SJ59
names: Similarity
messages: Belongs to the FBPase class 2 family.

362837:SCANT RS03175
gene id: 362837:SCANT_RS03175
uniprot id: A0A0M4K1M3
names: Subcellular Location Annotation
messages: Membrane

362837:SCANT RS00905
gene id: 362837:SCANT_RS00905
uniprot id: A0A0M4K0R5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

362837:SCANT RS01560
gene id: 362837:SCANT_RS01560
uniprot id: A0A0M4JWB2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

362837:SCANT RS04725
gene id: 362837:SCANT_RS04725
uniprot id: A0A0M4K267
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

362837:SCANT RS04745
gene id: 362837:SCANT_RS04745
uniprot id: A0A0M4JJ99
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

362837:SCANT RS03970
gene id: 362837:SCANT_RS03970
uniprot id: A0A0M4JJ00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

362837:SCANT RS04845
gene id: 362837:SCANT_RS04845
uniprot id: A0A0M4JKG1
names: Subcellular Location Annotation
messages: Membrane

362837:SCANT RS00570
gene id: 362837:SCANT_RS00570
uniprot id: A0A0M3SJ29
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

362837:SCANT RS04255
gene id: 362837:SCANT_RS04255
uniprot id: A0A0M3SJH3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

362837:SCANT RS04735
gene id: 362837:SCANT_RS04735
uniprot id: A0A0M4KD71
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Monomer.

362837:SCANT RS03940
gene id: 362837:SCANT_RS03940
uniprot id: A0A0M4JK39
names: Subcellular Location Annotation
messages: Membrane

362837:SCANT RS01295
gene id: 362837:SCANT_RS01295
uniprot id: A0A0M4KBX5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

362837:SCANT RS03630
gene id: 362837:SCANT_RS03630
uniprot id: A0A0M4JX37
names: Subcellular Location Annotation
messages: Membrane

362837:SCANT RS00255
gene id: 362837:SCANT_RS00255
uniprot id: A0A0M4JIU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Membrane

362837:SCANT RS05145
gene id: 362837:SCANT_RS05145
uniprot id: A0A0M4JKJ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

362837:SCANT RS00440
gene id: 362837:SCANT_RS00440
uniprot id: A0A0M3SJ24
names: Subcellular Location Annotation
messages: Membrane

362837:SCANT RS01220
gene id: 362837:SCANT_RS01220
uniprot id: A0A0M4K0V7
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

362837:SCANT RS05230
gene id: 362837:SCANT_RS05230
uniprot id: A0A0M4KDB9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

362837:SCANT RS04860
gene id: 362837:SCANT_RS04860
uniprot id: A0A0M4KD81
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

362837:SCANT RS00110
gene id: 362837:SCANT_RS00110
uniprot id: A0A0M4KDR2
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

362837:SCANT RS04790
gene id: 362837:SCANT_RS04790
uniprot id: A0A0M3SJJ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

362837:SCANT RS02970
gene id: 362837:SCANT_RS02970
uniprot id: A0A0M3SJC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

362837:SCANT RS04310
gene id: 362837:SCANT_RS04310
uniprot id: A0A0M3SJH5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

362837:SCANT RS00015
gene id: 362837:SCANT_RS00015
uniprot id: A0A0M5KGR1
names: Similarity
messages: Belongs to the type II topoisomerase GyrB family.

362837:SCANT RS04335
gene id: 362837:SCANT_RS04335
uniprot id: A0A0M4JK85
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

362837:SCANT RS04910
gene id: 362837:SCANT_RS04910
uniprot id: A0A0M4K293
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M3B family.
messages: Binds 1 zinc ion.
messages: Has oligopeptidase activity and degrades a variety of small bioactive peptides.

362837:SCANT RS00040
gene id: 362837:SCANT_RS00040
uniprot id: A0A0M3SJ08
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

362837:SCANT RS04390
gene id: 362837:SCANT_RS04390
uniprot id: A0A0M4JSZ6
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

362837:SCANT RS04700
gene id: 362837:SCANT_RS04700
uniprot id: A0A0M5KJD5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

362837:SCANT RS01425
gene id: 362837:SCANT_RS01425
uniprot id: A0A0M3SJ58
names: Subcellular Location Annotation
messages: Cytoplasm

362837:SCANT RS00220
gene id: 362837:SCANT_RS00220
uniprot id: A0A0M3SJ15
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

362837:SCANT RS05040
gene id: 362837:SCANT_RS05040
uniprot id: A0A0M5KLT6
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

362837:SCANT RS04260
gene id: 362837:SCANT_RS04260
uniprot id: A0A0M4JSX7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

362837:SCANT RS01040
gene id: 362837:SCANT_RS01040
uniprot id: A0A0M5KGU1
names: Similarity
messages: Belongs to the pyruvate kinase family.

362837:SCANT RS04825
gene id: 362837:SCANT_RS04825
uniprot id: A0A0M4KFE7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

362837:SCANT RS02850
gene id: 362837:SCANT_RS02850
uniprot id: A0A0M4JSE2
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

362837:SCANT RS04840
gene id: 362837:SCANT_RS04840
uniprot id: A0A0M3SJJ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

362837:SCANT RS02525
gene id: 362837:SCANT_RS02525
uniprot id: A0A0M4KEH3
names: Subcellular Location Annotation
messages: Membrane

362837:SCANT RS03745
gene id: 362837:SCANT_RS03745
uniprot id: A0A0M5KLP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Membrane

362837:SCANT RS00855
gene id: 362837:SCANT_RS00855
uniprot id: A0A0M4KBR7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

362837:SCANT RS00840
gene id: 362837:SCANT_RS00840
uniprot id: A0A0M4K0Q5
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
messages: Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

362837:SCANT RS05000
gene id: 362837:SCANT_RS05000
uniprot id: A0A0M4JXL3
names: Function
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

362837:SCANT RS02610
gene id: 362837:SCANT_RS02610
uniprot id: A0A0M4K1E4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

362837:SCANT RS04360
gene id: 362837:SCANT_RS04360
uniprot id: A0A0M3SJH7
names: Subcellular Location Annotation
messages: Membrane

362837:SCANT RS01805
gene id: 362837:SCANT_RS01805
uniprot id: A0A0M3SJ77
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

362837:SCANT RS00235
gene id: 362837:SCANT_RS00235
uniprot id: A0A0M4KDS5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

362837:SCANT RS01265
gene id: 362837:SCANT_RS01265
uniprot id: A0A0M4JS58
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

362837:SCANT RS04715
gene id: 362837:SCANT_RS04715
uniprot id: A0A0M4JT40
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

362837:SCANT RS01100
gene id: 362837:SCANT_RS01100
uniprot id: A0A0M5KC58
names: Subcellular Location Annotation
messages: Membrane

362837:SCANT RS02965
gene id: 362837:SCANT_RS02965
uniprot id: A0A0M4JSS5
names: PTM
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

362837:SCANT RS00010
gene id: 362837:SCANT_RS00010
uniprot id: A0A0M4K0G0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

362837:SCANT RS04575
gene id: 362837:SCANT_RS04575
uniprot id: A0A0M3SJI5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

362837:SCANT RS00230
gene id: 362837:SCANT_RS00230
uniprot id: A0A0M5KC73
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

362837:SCANT RS04125
gene id: 362837:SCANT_RS04125
uniprot id: A0A0M3SJG4
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

362837:SCANT RS05095
gene id: 362837:SCANT_RS05095
uniprot id: A0A0M4K2C0
names: Subcellular Location Annotation
messages: Membrane

362837:SCANT RS01680
gene id: 362837:SCANT_RS01680
uniprot id: A0A0M4JI62
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

362837:SCANT RS00045
gene id: 362837:SCANT_RS00045
uniprot id: A0A0M5KC45
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

362837:SCANT RS05090
gene id: 362837:SCANT_RS05090
uniprot id: A0A0M4JKI9
names: Subcellular Location Annotation
messages: Membrane

362837:SCANT RS04590
gene id: 362837:SCANT_RS04590
uniprot id: A0A0M4JT25
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LDH/MDH superfamily. LDH family.
messages: Catalyzes the conversion of lactate to pyruvate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

362837:SCANT RS02530
gene id: 362837:SCANT_RS02530
uniprot id: A0A0M4JSL5
names: Function
names: Similarity
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.

362837:SCANT RS00410
gene id: 362837:SCANT_RS00410
uniprot id: A0A0M4JVX6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

362837:SCANT RS05530
gene id: 362837:SCANT_RS05530
uniprot id: A0A0M4JT00
names: Similarity
messages: Belongs to the ABC transporter superfamily.

362837:SCANT RS04780
gene id: 362837:SCANT_RS04780
uniprot id: A0A0M4JKF5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

362837:SCANT RS01400
gene id: 362837:SCANT_RS01400
uniprot id: A0A0M4JJ68
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

362837:SCANT RS00585
gene id: 362837:SCANT_RS00585
uniprot id: A0A0M4KBP0
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

362837:SCANT RS00305
gene id: 362837:SCANT_RS00305
uniprot id: A0A0M4JRU8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

362837:SCANT RS04805
gene id: 362837:SCANT_RS04805
uniprot id: A0A0M4JJA8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

362837:SCANT RS00280
gene id: 362837:SCANT_RS00280
uniprot id: A0A0M4JHQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

362837:SCANT RS01290
gene id: 362837:SCANT_RS01290
uniprot id: A0A0M5KLF1
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

362837:SCANT RS04190
gene id: 362837:SCANT_RS04190
uniprot id: A0A0M4JT82
names: Similarity
messages: Belongs to the CutC family.

362837:SCANT RS04930
gene id: 362837:SCANT_RS04930
uniprot id: A0A0M4JJC5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

362837:SCANT RS03950
gene id: 362837:SCANT_RS03950
uniprot id: A0A0M4K1X5
names: Similarity
messages: Belongs to the lipase/esterase LIP3/BchO family.

362837:SCANT RS02235
gene id: 362837:SCANT_RS02235
uniprot id: A0A0M3SJ90
names: Subcellular Location Annotation
messages: Membrane

362837:SCANT RS01210
gene id: 362837:SCANT_RS01210
uniprot id: A0A0M4JRT8
names: Similarity
messages: Belongs to the FtsK/SpoIIIE/SftA family.

362837:SCANT RS04895
gene id: 362837:SCANT_RS04895
uniprot id: A0A0M4JTI5
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

362837:SCANT RS02725
gene id: 362837:SCANT_RS02725
uniprot id: A0A0M4JSC6
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Homodimer.

362837:SCANT RS01170
gene id: 362837:SCANT_RS01170
uniprot id: A0A0M4KBV7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

362837:SCANT RS01070
gene id: 362837:SCANT_RS01070
uniprot id: A0A0M4KDZ6
names: Subcellular Location Annotation
messages: Membrane

362837:SCANT RS04200
gene id: 362837:SCANT_RS04200
uniprot id: A0A0M4JK73
names: Similarity
messages: Belongs to the lipase/esterase LIP3/BchO family.

362837:SCANT RS04240
gene id: 362837:SCANT_RS04240
uniprot id: A0A0M5KCH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Membrane

362837:SCANT RS02985
gene id: 362837:SCANT_RS02985
uniprot id: A0A0M4K1J8
names: Similarity
messages: Belongs to the glycosyl hydrolase 32 family.

362837:SCANT RS01915
gene id: 362837:SCANT_RS01915
uniprot id: A0A0M4K147
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Could methylate the ribose at the nucleotide 34 wobble position in tRNA.
messages: Cytoplasm

362837:SCANT RS02045
gene id: 362837:SCANT_RS02045
uniprot id: A0A0M4KCA6
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family.

362837:SCANT RS00345
gene id: 362837:SCANT_RS00345
uniprot id: A0A0M4JHQ9
names: Similarity
messages: Belongs to the HPrK/P family.

362837:SCANT RS00310
gene id: 362837:SCANT_RS00310
uniprot id: A0A0M4JRH6
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

362837:SCANT RS03150
gene id: 362837:SCANT_RS03150
uniprot id: A0A0M4KEQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.
messages: Membrane

362837:SCANT RS03700
gene id: 362837:SCANT_RS03700
uniprot id: A0A0M4JX46
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

362837:SCANT RS01005
gene id: 362837:SCANT_RS01005
uniprot id: A0A0M3SJ43
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

362837:SCANT RS00285
gene id: 362837:SCANT_RS00285
uniprot id: A0A0M4JVV9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

362837:SCANT RS03895
gene id: 362837:SCANT_RS03895
uniprot id: A0A0M3SJF9
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

362837:SCANT RS04580
gene id: 362837:SCANT_RS04580
uniprot id: A0A0M4KFB5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

362837:SCANT RS04740
gene id: 362837:SCANT_RS04740
uniprot id: A0A0M3SJI8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

362837:SCANT RS03255
gene id: 362837:SCANT_RS03255
uniprot id: A0A0M4JIR3
names: Subcellular Location Annotation
messages: Membrane

362837:SCANT RS03670
gene id: 362837:SCANT_RS03670
uniprot id: A0A0M3SJF1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

362837:SCANT RS05200
gene id: 362837:SCANT_RS05200
uniprot id: A0A0M4JTM9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

362837:SCANT RS04935
gene id: 362837:SCANT_RS04935
uniprot id: A0A0M4JXK5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

362837:SCANT RS00180
gene id: 362837:SCANT_RS00180
uniprot id: A0A0M4JRT2
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

362837:SCANT RS04710
gene id: 362837:SCANT_RS04710
uniprot id: A0A0M4JTG1
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

362837:SCANT RS00035
gene id: 362837:SCANT_RS00035
uniprot id: A0A0M4JVS3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

362837:SCANT RS00785
gene id: 362837:SCANT_RS00785
uniprot id: A0A0M5KC48
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

362837:SCANT RS00845
gene id: 362837:SCANT_RS00845
uniprot id: A0A0M5KEC4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

362837:SCANT RS04610
gene id: 362837:SCANT_RS04610
uniprot id: A0A0M5KCH2
names: Subcellular Location Annotation
messages: Membrane

362837:SCANT RS01455
gene id: 362837:SCANT_RS01455
uniprot id: A0A0M3SJ63
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

362837:SCANT RS04570
gene id: 362837:SCANT_RS04570
uniprot id: A0A0M5KCI8
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

362837:SCANT RS04670
gene id: 362837:SCANT_RS04670
uniprot id: A0A0M5KEN8
names: Subcellular Location Annotation
messages: Membrane

362837:SCANT RS05225
gene id: 362837:SCANT_RS05225
uniprot id: A0A0M5KCJ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

362837:SCANT RS03705
gene id: 362837:SCANT_RS03705
uniprot id: A0A0M5KJA8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

362837:SCANT RS03500
gene id: 362837:SCANT_RS03500
uniprot id: A0A0M4JIU4
names: Subcellular Location Annotation
messages: Membrane

362837:SCANT RS01215
gene id: 362837:SCANT_RS01215
uniprot id: A0A0M4JJ43
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

362837:SCANT RS01025
gene id: 362837:SCANT_RS01025
uniprot id: A0A0M3SJ44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

362837:SCANT RS04565
gene id: 362837:SCANT_RS04565
uniprot id: A0A0M4JXF7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

362837:SCANT RS00245
gene id: 362837:SCANT_RS00245
uniprot id: A0A0M4JRU0
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

362837:SCANT RS00460
gene id: 362837:SCANT_RS00460
uniprot id: A0A0M4KBM2
names: Similarity
messages: Belongs to the lipase/esterase LIP3/BchO family.

362837:SCANT RS02625
gene id: 362837:SCANT_RS02625
uniprot id: A0A0M4KCH1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Probably interacts with PlsX.

362837:SCANT RS05115
gene id: 362837:SCANT_RS05115
uniprot id: A0A0M3SJK7
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

362837:SCANT RS03575
gene id: 362837:SCANT_RS03575
uniprot id: A0A0M5KCF8
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

362837:SCANT RS00210
gene id: 362837:SCANT_RS00210
uniprot id: A0A0M4KBJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

362837:SCANT RS00355
gene id: 362837:SCANT_RS00355
uniprot id: A0A0M5KC61
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Homodimer.

362837:SCANT RS05085
gene id: 362837:SCANT_RS05085
uniprot id: A0A0M3SJK2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

362837:SCANT RS04060
gene id: 362837:SCANT_RS04060
uniprot id: A0A0M4KF23
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

362837:SCANT RS00330
gene id: 362837:SCANT_RS00330
uniprot id: A0A0M5KGS1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

362837:SCANT RS05170
gene id: 362837:SCANT_RS05170
uniprot id: A0A0M4JJF6
names: Subcellular Location Annotation
messages: Membrane

362837:SCANT RS01260
gene id: 362837:SCANT_RS01260
uniprot id: A0A0M4KE19
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

362837:SCANT RS00265
gene id: 362837:SCANT_RS00265
uniprot id: A0A0M5KLB9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

362837:SCANT RS04195
gene id: 362837:SCANT_RS04195
uniprot id: A0A0M4JSW9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

362837:SCANT RS03675
gene id: 362837:SCANT_RS03675
uniprot id: A0A0M4K1T9
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

362837:SCANT RS04875
gene id: 362837:SCANT_RS04875
uniprot id: A0A0M4JXJ7
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

362837:SCANT RS04730
gene id: 362837:SCANT_RS04730
uniprot id: A0A0M5KLS7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

362837:SCANT RS04705
gene id: 362837:SCANT_RS04705
uniprot id: A0A0M4KFD6
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

362837:SCANT RS05055
gene id: 362837:SCANT_RS05055
uniprot id: A0A0M4JXM2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

362837:SCANT RS05105
gene id: 362837:SCANT_RS05105
uniprot id: A0A0M4KDA6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

362837:SCANT RS04755
gene id: 362837:SCANT_RS04755
uniprot id: A0A0M5KCK4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

362837:SCANT RS01510
gene id: 362837:SCANT_RS01510
uniprot id: A0A0M4KE56
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmG family. TrmFO subfamily.
messages: Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
messages: Cytoplasm

362837:SCANT RS04925
gene id: 362837:SCANT_RS04925
uniprot id: A0A0M4KD87
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

362837:SCANT RS02060
gene id: 362837:SCANT_RS02060
uniprot id: A0A0M4JWH6
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family.

362837:SCANT RS01665
gene id: 362837:SCANT_RS01665
uniprot id: A0A0M5KGW1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

362837:SCANT RS02645
gene id: 362837:SCANT_RS02645
uniprot id: A0A0M5KCC9
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

362837:SCANT RS01445
gene id: 362837:SCANT_RS01445
uniprot id: A0A0M4KE47
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

362837:SCANT RS00120
gene id: 362837:SCANT_RS00120
uniprot id: A0A0M3SJ11
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

362837:SCANT RS01870
gene id: 362837:SCANT_RS01870
uniprot id: A0A0M4JWF2
names: Similarity
messages: Belongs to the RibF family.

362837:SCANT RS02910
gene id: 362837:SCANT_RS02910
uniprot id: A0A0M4JSF0
names: Subcellular Location Annotation
messages: Membrane

362837:SCANT RS03865
gene id: 362837:SCANT_RS03865
uniprot id: A0A0M3SJF4
names: Domain
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

362837:SCANT RS03195
gene id: 362837:SCANT_RS03195
uniprot id: A0A0M4JIQ4
names: Cofactor
messages: Binds 1 Mg(2+) ion per trimer.

362837:SCANT RS01580
gene id: 362837:SCANT_RS01580
uniprot id: A0A0M4JS96
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

362837:SCANT RS03030
gene id: 362837:SCANT_RS03030
uniprot id: A0A0M4JST3
names: Similarity
messages: Belongs to the LacAB/RpiB family.

362837:SCANT RS00465
gene id: 362837:SCANT_RS00465
uniprot id: A0A0M4JHS3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

362837:SCANT RS00090
gene id: 362837:SCANT_RS00090
uniprot id: A0A0M3SJ10
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

362837:SCANT RS04220
gene id: 362837:SCANT_RS04220
uniprot id: A0A0M4KD15
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

362837:SCANT RS04215
gene id: 362837:SCANT_RS04215
uniprot id: A0A0M5KH30
names: Function
names: Similarity
messages: Belongs to the UPF0122 family.
messages: Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein.

362837:SCANT RS01555
gene id: 362837:SCANT_RS01555
uniprot id: A0A0M3SJ67
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

362837:SCANT RS05075
gene id: 362837:SCANT_RS05075
uniprot id: A0A0M4JTK9
names: Similarity
messages: Belongs to the ParB family.

362837:SCANT RS03250
gene id: 362837:SCANT_RS03250
uniprot id: A0A0M4KCP7
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

362837:SCANT RS04455
gene id: 362837:SCANT_RS04455
uniprot id: A0A0M4JKA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

362837:SCANT RS03870
gene id: 362837:SCANT_RS03870
uniprot id: A0A0M4JT41
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

362837:SCANT RS05190
gene id: 362837:SCANT_RS05190
uniprot id: A0A0M5KCK7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

362837:SCANT RS03105
gene id: 362837:SCANT_RS03105
uniprot id: A0A0M4JJT9
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane.

362837:SCANT RS03480
gene id: 362837:SCANT_RS03480
uniprot id: A0A0M4K1R4
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

362837:SCANT RS00595
gene id: 362837:SCANT_RS00595
uniprot id: A0A0M4JHU0
names: Subcellular Location Annotation
messages: Membrane

362837:SCANT RS04975
gene id: 362837:SCANT_RS04975
uniprot id: A0A0M4K2A3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

362837:SCANT RS03725
gene id: 362837:SCANT_RS03725
uniprot id: A0A0M4JSQ6
names: Activity Regulation
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.

362837:SCANT RS00365
gene id: 362837:SCANT_RS00365
uniprot id: A0A0M4JRV5
names: Function
names: Similarity
messages: Belongs to the WhiA family.
messages: Involved in cell division and chromosome segregation.

362837:SCANT RS04720
gene id: 362837:SCANT_RS04720
uniprot id: A0A0M4JKE4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

362837:SCANT RS03365
gene id: 362837:SCANT_RS03365
uniprot id: A0A0M3SJD9
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

362837:SCANT RS01035
gene id: 362837:SCANT_RS01035
uniprot id: A0A0M4K0S9
names: Similarity
messages: Belongs to the pyruvate kinase family.

362837:SCANT RS00290
gene id: 362837:SCANT_RS00290
uniprot id: A0A0M3SJ18
names: Similarity
messages: Belongs to the ATPase epsilon chain family.

362837:SCANT RS02780
gene id: 362837:SCANT_RS02780
uniprot id: A0A0M4JSP7
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

362837:SCANT RS04105
gene id: 362837:SCANT_RS04105
uniprot id: A0A0M3SJG7
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

362837:SCANT RS04685
gene id: 362837:SCANT_RS04685
uniprot id: A0A0M4JJ91
names: Subcellular Location Annotation
messages: Membrane

362837:SCANT RS03625
gene id: 362837:SCANT_RS03625
uniprot id: A0A0M4JIW0
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

362837:SCANT RS01010
gene id: 362837:SCANT_RS01010
uniprot id: A0A0M4KDY8
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

362837:SCANT RS01460
gene id: 362837:SCANT_RS01460
uniprot id: A0A0M4JRW7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
messages: Cytoplasm
messages: Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity.

362837:SCANT RS03750
gene id: 362837:SCANT_RS03750
uniprot id: A0A0M4KCW0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

362837:SCANT RS02900
gene id: 362837:SCANT_RS02900
uniprot id: A0A0M4KEM3
names: Subcellular Location Annotation
messages: Membrane

362837:SCANT RS00005
gene id: 362837:SCANT_RS00005
uniprot id: A0A0M4JIR2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

362837:SCANT RS00175
gene id: 362837:SCANT_RS00175
uniprot id: A0A0M4KDS0
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

362837:SCANT RS05005
gene id: 362837:SCANT_RS05005
uniprot id: A0A0M5KJE5
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

362837:SCANT RS03995
gene id: 362837:SCANT_RS03995
uniprot id: A0A0M4JSU1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

362837:SCANT RS04775
gene id: 362837:SCANT_RS04775
uniprot id: A0A0M4JT46
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

362837:SCANT RS00115
gene id: 362837:SCANT_RS00115
uniprot id: A0A0M4JRS5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

362837:SCANT RS01985
gene id: 362837:SCANT_RS01985
uniprot id: A0A0M5KGW9
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

362837:SCANT RS01875
gene id: 362837:SCANT_RS01875
uniprot id: A0A0M3SJ76
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

362837:SCANT RS00325
gene id: 362837:SCANT_RS00325
uniprot id: A0A0M4K0J7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

362837:SCANT RS04785
gene id: 362837:SCANT_RS04785
uniprot id: A0A0M4K278
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

362837:SCANT RS01470
gene id: 362837:SCANT_RS01470
uniprot id: A0A0M4K0Y9
names: Similarity
messages: Belongs to the phosphohexose mutase family.

362837:SCANT RS00710
gene id: 362837:SCANT_RS00710
uniprot id: A0A0M4JRM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

362837:SCANT RS02925
gene id: 362837:SCANT_RS02925
uniprot id: A0A0M4K1I9
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

362837:SCANT RS01965
gene id: 362837:SCANT_RS01965
uniprot id: A0A0M4JS33
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

362837:SCANT RS00505
gene id: 362837:SCANT_RS00505
uniprot id: A0A0M4JIX1
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

362837:SCANT RS01825
gene id: 362837:SCANT_RS01825
uniprot id: A0A0M3SJ74
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

362837:SCANT RS01495
gene id: 362837:SCANT_RS01495
uniprot id: A0A0M4JWA4
names: Similarity
messages: Belongs to the DprA/Smf family.

362837:SCANT RS00300
gene id: 362837:SCANT_RS00300
uniprot id: A0A0M4KDT0
names: Similarity
messages: Belongs to the IMPACT family.

362837:SCANT RS01820
gene id: 362837:SCANT_RS01820
uniprot id: A0A0M4KE95
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

362837:SCANT RS01150
gene id: 362837:SCANT_RS01150
uniprot id: A0A0M4JJ35
names: Subcellular Location Annotation
messages: Membrane

362837:SCANT RS01620
gene id: 362837:SCANT_RS01620
uniprot id: A0A0M4JWC1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

362837:SCANT RS03380
gene id: 362837:SCANT_RS03380
uniprot id: A0A0M4JWZ9
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

362837:SCANT RS04680
gene id: 362837:SCANT_RS04680
uniprot id: A0A0M4KD66
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

362837:SCANT RS01285
gene id: 362837:SCANT_RS01285
uniprot id: A0A0M4K0W6
names: Subcellular Location Annotation
messages: Membrane

362837:SCANT RS03000
gene id: 362837:SCANT_RS03000
uniprot id: A0A0M4KCL7
names: Subcellular Location Annotation
messages: Membrane

362837:SCANT RS00320
gene id: 362837:SCANT_RS00320
uniprot id: A0A0M3SJ19
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

362837:SCANT RS03875
gene id: 362837:SCANT_RS03875
uniprot id: A0A0M4JSS3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

362837:SCANT RS01065
gene id: 362837:SCANT_RS01065
uniprot id: A0A0M5KC77
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

362837:SCANT RS01745
gene id: 362837:SCANT_RS01745
uniprot id: A0A0M4JWD6
names: Subcellular Location Annotation
messages: Membrane

362837:SCANT RS04595
gene id: 362837:SCANT_RS04595
uniprot id: A0A0M3SJI2
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

362837:SCANT RS05310
gene id: 362837:SCANT_RS05310
uniprot id: A0A0M3SJJ1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

362837:SCANT RS01420
gene id: 362837:SCANT_RS01420
uniprot id: A0A0M4KC25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecU family.
messages: Cytoplasm

362837:SCANT RS00450
gene id: 362837:SCANT_RS00450
uniprot id: A0A0M4K0L1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

362837:SCANT RS01185
gene id: 362837:SCANT_RS01185
uniprot id: A0A0M4JW60
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

362837:SCANT RS00215
gene id: 362837:SCANT_RS00215
uniprot id: A0A0M4JHP1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

362837:SCANT RS00360
gene id: 362837:SCANT_RS00360
uniprot id: A0A0M4KDT3
names: Similarity
messages: Belongs to the Lgt family.

362837:SCANT RS02755
gene id: 362837:SCANT_RS02755
uniprot id: A0A0M4JIJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

362837:SCANT RS03775
gene id: 362837:SCANT_RS03775
uniprot id: A0A0M4KEY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

362837:SCANT RS04800
gene id: 362837:SCANT_RS04800
uniprot id: A0A0M4KD76
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

362837:SCANT RS01410
gene id: 362837:SCANT_RS01410
uniprot id: A0A0M4K0Y1
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

362837:SCANT RS01345
gene id: 362837:SCANT_RS01345
uniprot id: A0A0M4K0X4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

362837:SCANT RS04020
gene id: 362837:SCANT_RS04020
uniprot id: A0A0M4KCZ1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

362837:SCANT RS04270
gene id: 362837:SCANT_RS04270
uniprot id: A0A0M4K216
names: Subcellular Location Annotation
messages: Membrane

362837:SCANT RS03820
gene id: 362837:SCANT_RS03820
uniprot id: A0A0M3SJF7
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

362837:SCANT RS03335
gene id: 362837:SCANT_RS03335
uniprot id: A0A0M3SJD4
names: Subcellular Location Annotation
messages: Membrane

362837:SCANT RS00820
gene id: 362837:SCANT_RS00820
uniprot id: A0A0M3SJ36
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

362837:SCANT RS03800
gene id: 362837:SCANT_RS03800
uniprot id: A0A0M4K1V4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

362837:SCANT RS04115
gene id: 362837:SCANT_RS04115
uniprot id: A0A0M5KCI5
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

362837:SCANT RS02505
gene id: 362837:SCANT_RS02505
uniprot id: A0A0M4JIG0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

362837:SCANT RS05485
gene id: 362837:SCANT_RS05485
uniprot id: A0A0M4KDA1
names: Similarity
messages: Belongs to the RpoE family.

362837:SCANT RS00185
gene id: 362837:SCANT_RS00185
uniprot id: A0A0M4JRF9
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

362837:SCANT RS05100
gene id: 362837:SCANT_RS05100
uniprot id: A0A0M5KLR6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

362837:SCANT RS03825
gene id: 362837:SCANT_RS03825
uniprot id: A0A0M4JX59
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

362837:SCANT RS01715
gene id: 362837:SCANT_RS01715
uniprot id: A0A0M4JJB0
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

362837:SCANT RS04290
gene id: 362837:SCANT_RS04290
uniprot id: A0A0M4JJ40
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

362837:SCANT RS03215
gene id: 362837:SCANT_RS03215
uniprot id: A0A0M4JSV7
names: Function
messages: Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins.

362837:SCANT RS01910
gene id: 362837:SCANT_RS01910
uniprot id: A0A0M3SJ81
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

362837:SCANT RS01245
gene id: 362837:SCANT_RS01245
uniprot id: A0A0M4JW68
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

362837:SCANT RS03165
gene id: 362837:SCANT_RS03165
uniprot id: A0A0M4JJU7
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

362837:SCANT RS05010
gene id: 362837:SCANT_RS05010
uniprot id: A0A0M4KFG7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.

362837:SCANT RS04470
gene id: 362837:SCANT_RS04470
uniprot id: A0A0M5KLP7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

362837:SCANT RS01380
gene id: 362837:SCANT_RS01380
uniprot id: A0A0M5KC87
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

362837:SCANT RS01315
gene id: 362837:SCANT_RS01315
uniprot id: A0A0M5KCG7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

362837:SCANT RS01175
gene id: 362837:SCANT_RS01175
uniprot id: A0A0M3SJ49
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

362837:SCANT RS03985
gene id: 362837:SCANT_RS03985
uniprot id: A0A0M4JT56
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.