358396:CHINAEXTREME RS20125
gene id: 358396:CHINAEXTREME_RS20125
uniprot id: M0LUW2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

358396:CHINAEXTREME RS00260
gene id: 358396:CHINAEXTREME_RS00260
uniprot id: M0LW90
names: Function
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.

358396:CHINAEXTREME RS11760
gene id: 358396:CHINAEXTREME_RS11760
uniprot id: A0A1P8LRJ3
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

358396:CHINAEXTREME RS04055
gene id: 358396:CHINAEXTREME_RS04055
uniprot id: M0LQI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

358396:CHINAEXTREME RS11325
gene id: 358396:CHINAEXTREME_RS11325
uniprot id: M0L335
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 2 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm

358396:CHINAEXTREME RS07485
gene id: 358396:CHINAEXTREME_RS07485
uniprot id: M0LXE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

358396:CHINAEXTREME RS04060
gene id: 358396:CHINAEXTREME_RS04060
uniprot id: M0LRM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

358396:CHINAEXTREME RS12105
gene id: 358396:CHINAEXTREME_RS12105
uniprot id: M0LHZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

358396:CHINAEXTREME RS19660
gene id: 358396:CHINAEXTREME_RS19660
uniprot id: M0LS79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

358396:CHINAEXTREME RS16905
gene id: 358396:CHINAEXTREME_RS16905
uniprot id: M0LS06
names: Similarity
messages: Belongs to the DtxR/MntR family.

358396:CHINAEXTREME RS18915
gene id: 358396:CHINAEXTREME_RS18915
uniprot id: M0LSI6
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the peroxidase family. Peroxidase/catalase subfamily.
messages: Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.
messages: Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

358396:CHINAEXTREME RS11235
gene id: 358396:CHINAEXTREME_RS11235
uniprot id: M0L4C1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit.

358396:CHINAEXTREME RS18975
gene id: 358396:CHINAEXTREME_RS18975
uniprot id: M0LR85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

358396:CHINAEXTREME RS04640
gene id: 358396:CHINAEXTREME_RS04640
uniprot id: M0LPN5
names: Similarity
messages: Belongs to the beta-eliminating lyase family.

358396:CHINAEXTREME RS08775
gene id: 358396:CHINAEXTREME_RS08775
uniprot id: A0A1P8LQ26
names: Function
messages: Decarboxylates L-threonine-O-3-phosphate to yield (R)-1-amino-2-propanol O-2-phosphate, the precursor for the linkage between the nucleotide loop and the corrin ring in cobalamin.

358396:CHINAEXTREME RS18985
gene id: 358396:CHINAEXTREME_RS18985
uniprot id: M0LVI6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

358396:CHINAEXTREME RS17710
gene id: 358396:CHINAEXTREME_RS17710
uniprot id: M0LDF2
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
messages: Binds 2 nickel ions per subunit.
messages: Carbamylation allows a single lysine to coordinate two nickel ions.
messages: Carboxylation allows a single lysine to coordinate two nickel ions.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

358396:CHINAEXTREME RS13550
gene id: 358396:CHINAEXTREME_RS13550
uniprot id: A0A1P8LSH5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Brp/Blh beta-carotene diooxygenase family.
messages: Catalyzes the cleavage of beta-carotene at its central double bond (15,15') to yield two molecules of all-trans-retinal.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

358396:CHINAEXTREME RS14880
gene id: 358396:CHINAEXTREME_RS14880
uniprot id: M0LEW1
names: Function
names: Similarity
messages: Belongs to the CDC6/cdc18 family.
messages: Involved in regulation of DNA replication.

358396:CHINAEXTREME RS17940
gene id: 358396:CHINAEXTREME_RS17940
uniprot id: M0LDJ3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: S-layer

358396:CHINAEXTREME RS12965
gene id: 358396:CHINAEXTREME_RS12965
uniprot id: M0LKI1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: In the C-terminal section; belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Membrane

358396:CHINAEXTREME RS05175
gene id: 358396:CHINAEXTREME_RS05175
uniprot id: M0LLS5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

358396:CHINAEXTREME RS18155
gene id: 358396:CHINAEXTREME_RS18155
uniprot id: M0LPZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Archaeal shikimate kinase subfamily.
messages: Cytoplasm

358396:CHINAEXTREME RS12290
gene id: 358396:CHINAEXTREME_RS12290
uniprot id: M0LLG3
names: Similarity
messages: Belongs to the PEPCase type 1 family.

358396:CHINAEXTREME RS08075
gene id: 358396:CHINAEXTREME_RS08075
uniprot id: M0LVQ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the archaeal DnaG primase family.
messages: Forms a ternary complex with MCM helicase and DNA. Component of the archaeal exosome complex.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome.

358396:CHINAEXTREME RS03245
gene id: 358396:CHINAEXTREME_RS03245
uniprot id: M0LP41
names: Similarity
messages: Belongs to the universal ribosomal protein uL16 family.

358396:CHINAEXTREME RS16440
gene id: 358396:CHINAEXTREME_RS16440
uniprot id: M0LEH4
names: Similarity
messages: Belongs to the phosphohexose mutase family.

358396:CHINAEXTREME RS01515
gene id: 358396:CHINAEXTREME_RS01515
uniprot id: M0LF26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

358396:CHINAEXTREME RS02445
gene id: 358396:CHINAEXTREME_RS02445
uniprot id: M0LEL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC41A transporter family.
messages: Membrane

358396:CHINAEXTREME RS09970
gene id: 358396:CHINAEXTREME_RS09970
uniprot id: M0L4P9
names: Similarity
messages: Belongs to the eukaryotic/archaeal PrmC-related family.

358396:CHINAEXTREME RS12755
gene id: 358396:CHINAEXTREME_RS12755
uniprot id: M0LHA0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

358396:CHINAEXTREME RS07570
gene id: 358396:CHINAEXTREME_RS07570
uniprot id: M0LUZ5
names: Subcellular Location Annotation
messages: Cytoplasm

358396:CHINAEXTREME RS00250
gene id: 358396:CHINAEXTREME_RS00250
uniprot id: M0LS18
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

358396:CHINAEXTREME RS16545
gene id: 358396:CHINAEXTREME_RS16545
uniprot id: M0LBA2
names: Subcellular Location Annotation
messages: Membrane

358396:CHINAEXTREME RS14520
gene id: 358396:CHINAEXTREME_RS14520
uniprot id: M0L5D4
names: Subcellular Location Annotation
messages: Membrane

358396:CHINAEXTREME RS03425
gene id: 358396:CHINAEXTREME_RS03425
uniprot id: M0LP77
names: Subcellular Location Annotation
messages: Membrane

358396:CHINAEXTREME RS15095
gene id: 358396:CHINAEXTREME_RS15095
uniprot id: M0LFR3
names: Function
names: Similarity
messages: Belongs to the DPH1/DPH2 family.
messages: Catalyzes the first step of diphthamide biosynthesis, i.e. the transfer of the 3-amino-3-carboxypropyl group from S-adenosyl-L-methionine (SAM) to the C2 position of the imidazole ring of the target histidine residue in translation elongation factor 2 (EF-2).

358396:CHINAEXTREME RS17085
gene id: 358396:CHINAEXTREME_RS17085
uniprot id: A0A1P8LWK3
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family. N(4) subfamily.

358396:CHINAEXTREME RS09110
gene id: 358396:CHINAEXTREME_RS09110
uniprot id: M0L6N3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

358396:CHINAEXTREME RS16165
gene id: 358396:CHINAEXTREME_RS16165
uniprot id: M0LCC8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

358396:CHINAEXTREME RS04225
gene id: 358396:CHINAEXTREME_RS04225
uniprot id: A0A1P8LML0
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

358396:CHINAEXTREME RS00240
gene id: 358396:CHINAEXTREME_RS00240
uniprot id: M0LVH0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DeoC/FbaB aldolase family. ADHS subfamily.
messages: Catalyzes a transaldol reaction between 6-deoxy-5-ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids.
messages: Homodecamer.

358396:CHINAEXTREME RS05770
gene id: 358396:CHINAEXTREME_RS05770
uniprot id: M0LMY0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CetZ family.
messages: Cytoplasm
messages: Involved in cell shape control.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

358396:CHINAEXTREME RS14815
gene id: 358396:CHINAEXTREME_RS14815
uniprot id: A0A1P8LT43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

358396:CHINAEXTREME RS05760
gene id: 358396:CHINAEXTREME_RS05760
uniprot id: M0LJL5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm

358396:CHINAEXTREME RS18710
gene id: 358396:CHINAEXTREME_RS18710
uniprot id: M0LPY8
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TFE family.
messages: Monomer. Interaction with RNA polymerase subunits RpoF and RpoE is necessary for Tfe stimulatory transcription activity. Able to interact with Tbp and RNA polymerase in the absence of DNA promoter. Interacts both with the preinitiation and elongation complexes.
messages: The winged helix domain is involved in binding to DNA in the preinitiation complex.
messages: Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes. Seems to translocate with the RNA polymerase following initiation and acts by binding to the non template strand of the transcription bubble in elongation complexes.

358396:CHINAEXTREME RS13565
gene id: 358396:CHINAEXTREME_RS13565
uniprot id: M0LGM0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the 50S ribosomal subunit. Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Forms a heptameric L10(L12)2(L12)2(L12)2 complex, where L10 forms an elongated spine to which the L12 dimers bind in a sequential fashion.

358396:CHINAEXTREME RS16555
gene id: 358396:CHINAEXTREME_RS16555
uniprot id: M0LCL4
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

358396:CHINAEXTREME RS18465
gene id: 358396:CHINAEXTREME_RS18465
uniprot id: M0LQ32
names: Subcellular Location Annotation
messages: Membrane

358396:CHINAEXTREME RS17615
gene id: 358396:CHINAEXTREME_RS17615
uniprot id: M0LDF3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

358396:CHINAEXTREME RS01670
gene id: 358396:CHINAEXTREME_RS01670
uniprot id: M0LJI4
names: Subcellular Location Annotation
messages: Membrane

358396:CHINAEXTREME RS16980
gene id: 358396:CHINAEXTREME_RS16980
uniprot id: M0LRZ2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Catalyzes the deamination of dCTP to dUTP.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

358396:CHINAEXTREME RS20200
gene id: 358396:CHINAEXTREME_RS20200
uniprot id: M0LQU4
names: Subcellular Location Annotation
messages: Membrane

358396:CHINAEXTREME RS00540
gene id: 358396:CHINAEXTREME_RS00540
uniprot id: M0L1G1
names: Function
names: Similarity
messages: Belongs to the group II decarboxylase family. MfnA subfamily.
messages: Catalyzes the decarboxylation of L-aspartate to produce beta-alanine.

358396:CHINAEXTREME RS12605
gene id: 358396:CHINAEXTREME_RS12605
uniprot id: M0LJ43
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

358396:CHINAEXTREME RS07085
gene id: 358396:CHINAEXTREME_RS07085
uniprot id: M0LY92
names: Function
names: Similarity
messages: Belongs to the GTP-dependent DPCK family.
messages: Catalyzes the GTP-dependent phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (CoA).

358396:CHINAEXTREME RS08695
gene id: 358396:CHINAEXTREME_RS08695
uniprot id: M0L6F8
names: Subcellular Location Annotation
messages: Membrane

358396:CHINAEXTREME RS19705
gene id: 358396:CHINAEXTREME_RS19705
uniprot id: M0LU95
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

358396:CHINAEXTREME RS15535
gene id: 358396:CHINAEXTREME_RS15535
uniprot id: M0LGV2
names: Subcellular Location Annotation
messages: Membrane

358396:CHINAEXTREME RS07910
gene id: 358396:CHINAEXTREME_RS07910
uniprot id: A0A1P8LPH8
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

358396:CHINAEXTREME RS02700
gene id: 358396:CHINAEXTREME_RS02700
uniprot id: M0LIX0
names: Subcellular Location Annotation
messages: Membrane

358396:CHINAEXTREME RS12765
gene id: 358396:CHINAEXTREME_RS12765
uniprot id: M0LFY7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the archaeal FAD synthase family.
messages: Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

358396:CHINAEXTREME RS19905
gene id: 358396:CHINAEXTREME_RS19905
uniprot id: M0LS37
names: Subcellular Location Annotation
messages: Membrane

358396:CHINAEXTREME RS10310
gene id: 358396:CHINAEXTREME_RS10310
uniprot id: M0L6S9
names: Subcellular Location Annotation
messages: Membrane

358396:CHINAEXTREME RS13885
gene id: 358396:CHINAEXTREME_RS13885
uniprot id: M0LFE0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic/archaeal RNase P protein component 1 family.
messages: Consists of a catalytic RNA component and at least 4-5 protein subunits.
messages: Cytoplasm
messages: Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.

358396:CHINAEXTREME RS17555
gene id: 358396:CHINAEXTREME_RS17555
uniprot id: M0LGP3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase-20S proteasome association which triggers gate opening, and supports translocation of unfolded substrates.
messages: Belongs to the AAA ATPase family.
messages: Consists of three main regions, an N-terminal coiled-coil domain that may assist in substrate recognition, an interdomain involved in PAN hexamerization, and a C-terminal ATPase domain of the AAA type.
messages: Cytoplasm
messages: Homohexamer. The hexameric complex has a two-ring architecture resembling a top hat that caps the 20S proteasome core at one or both ends. Upon ATP-binding, the C-terminus of PAN interacts with the alpha-rings of the proteasome core by binding to the intersubunit pockets.

358396:CHINAEXTREME RS15905
gene id: 358396:CHINAEXTREME_RS15905
uniprot id: M0LAY1
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

358396:CHINAEXTREME RS15865
gene id: 358396:CHINAEXTREME_RS15865
uniprot id: M0LFG0
names: Similarity
messages: Belongs to the glutaredoxin family. Monothiol subfamily.

358396:CHINAEXTREME RS01560
gene id: 358396:CHINAEXTREME_RS01560
uniprot id: M0LGH1
names: Caution
names: Similarity
messages: Belongs to the UPF0391 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

358396:CHINAEXTREME RS06955
gene id: 358396:CHINAEXTREME_RS06955
uniprot id: M0LU64
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

358396:CHINAEXTREME RS14045
gene id: 358396:CHINAEXTREME_RS14045
uniprot id: M0LFH3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

358396:CHINAEXTREME RS12620
gene id: 358396:CHINAEXTREME_RS12620
uniprot id: M0LHU4
names: Similarity
messages: Belongs to the acylphosphatase family.

358396:CHINAEXTREME RS08140
gene id: 358396:CHINAEXTREME_RS08140
uniprot id: M0LWK2
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

358396:CHINAEXTREME RS07220
gene id: 358396:CHINAEXTREME_RS07220
uniprot id: M0LV72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm

358396:CHINAEXTREME RS08430
gene id: 358396:CHINAEXTREME_RS08430
uniprot id: M0LWC0
names: Similarity
messages: Belongs to the threonine synthase family.

358396:CHINAEXTREME RS13925
gene id: 358396:CHINAEXTREME_RS13925
uniprot id: M0LJX4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L24e.

358396:CHINAEXTREME RS13220
gene id: 358396:CHINAEXTREME_RS13220
uniprot id: M0LG28
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

358396:CHINAEXTREME RS03435
gene id: 358396:CHINAEXTREME_RS03435
uniprot id: M0LS69
names: Similarity
messages: Belongs to the selenium-binding protein family.

358396:CHINAEXTREME RS20205
gene id: 358396:CHINAEXTREME_RS20205
uniprot id: M0LUU3
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

358396:CHINAEXTREME RS04905
gene id: 358396:CHINAEXTREME_RS04905
uniprot id: M0LN17
names: Subcellular Location Annotation
messages: Membrane

358396:CHINAEXTREME RS17725
gene id: 358396:CHINAEXTREME_RS17725
uniprot id: M0LGS4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UreD family.
messages: Cytoplasm
messages: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
messages: UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

358396:CHINAEXTREME RS17620
gene id: 358396:CHINAEXTREME_RS17620
uniprot id: A0A1P8LWF6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

358396:CHINAEXTREME RS11250
gene id: 358396:CHINAEXTREME_RS11250
uniprot id: M0L7K7
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL18 family.

358396:CHINAEXTREME RS19665
gene id: 358396:CHINAEXTREME_RS19665
uniprot id: A0A1P8LVQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

358396:CHINAEXTREME RS09075
gene id: 358396:CHINAEXTREME_RS09075
uniprot id: M0L9P6
names: Caution
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

358396:CHINAEXTREME RS08200
gene id: 358396:CHINAEXTREME_RS08200
uniprot id: M0LVN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

358396:CHINAEXTREME RS05345
gene id: 358396:CHINAEXTREME_RS05345
uniprot id: M0LKL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

358396:CHINAEXTREME RS15705
gene id: 358396:CHINAEXTREME_RS15705
uniprot id: M0LG09
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

358396:CHINAEXTREME RS13420
gene id: 358396:CHINAEXTREME_RS13420
uniprot id: M0LG54
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

358396:CHINAEXTREME RS02940
gene id: 358396:CHINAEXTREME_RS02940
uniprot id: M0LNJ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Catalyzes the NAD-dependent oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Homodimer.

358396:CHINAEXTREME RS05790
gene id: 358396:CHINAEXTREME_RS05790
uniprot id: M0LL70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

358396:CHINAEXTREME RS17305
gene id: 358396:CHINAEXTREME_RS17305
uniprot id: M0LP03
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

358396:CHINAEXTREME RS15990
gene id: 358396:CHINAEXTREME_RS15990
uniprot id: M0LFI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

358396:CHINAEXTREME RS19405
gene id: 358396:CHINAEXTREME_RS19405
uniprot id: M0LVB7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

358396:CHINAEXTREME RS12835
gene id: 358396:CHINAEXTREME_RS12835
uniprot id: M0LFW1
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.

358396:CHINAEXTREME RS14945
gene id: 358396:CHINAEXTREME_RS14945
uniprot id: M0L9D5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SRP19 family.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds directly to 7S RNA and mediates binding of the 54 kDa subunit of the SRP.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. Archaeal SRP consists of a 7S RNA molecule of 300 nucleotides and two protein subunits: SRP54 and SRP19.

358396:CHINAEXTREME RS03770
gene id: 358396:CHINAEXTREME_RS03770
uniprot id: M0LMC0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PCNA family.
messages: Homotrimer. The subunits circularize to form a toroid; DNA passes through its center. Replication factor C (RFC) is required to load the toroid on the DNA.
messages: Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication.
messages: Sliding clamp subunit. Responsible for tethering the catalytic subunit of DNA polymerase to DNA during high-speed replication.

358396:CHINAEXTREME RS12670
gene id: 358396:CHINAEXTREME_RS12670
uniprot id: M0LFW9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TOP6A family.
messages: Homodimer. Heterotetramer of two Top6A and two Top6B chains.
messages: Relaxes both positive and negative superturns and exhibits a strong decatenase activity.

358396:CHINAEXTREME RS01340
gene id: 358396:CHINAEXTREME_RS01340
uniprot id: M0LH31
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

358396:CHINAEXTREME RS11625
gene id: 358396:CHINAEXTREME_RS11625
uniprot id: A0A1P8LRJ1
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

358396:CHINAEXTREME RS02360
gene id: 358396:CHINAEXTREME_RS02360
uniprot id: M0LJ65
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

358396:CHINAEXTREME RS03995
gene id: 358396:CHINAEXTREME_RS03995
uniprot id: M0LMA6
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

358396:CHINAEXTREME RS08235
gene id: 358396:CHINAEXTREME_RS08235
uniprot id: M0LYT2
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

358396:CHINAEXTREME RS05925
gene id: 358396:CHINAEXTREME_RS05925
uniprot id: A0A1P8LNJ7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

358396:CHINAEXTREME RS02205
gene id: 358396:CHINAEXTREME_RS02205
uniprot id: M0LJ90
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

358396:CHINAEXTREME RS14035
gene id: 358396:CHINAEXTREME_RS14035
uniprot id: M0LFK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

358396:CHINAEXTREME RS12375
gene id: 358396:CHINAEXTREME_RS12375
uniprot id: A0A1P8LRV9
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

358396:CHINAEXTREME RS17290
gene id: 358396:CHINAEXTREME_RS17290
uniprot id: M0LT35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0391 family.
messages: Cell membrane

358396:CHINAEXTREME RS14595
gene id: 358396:CHINAEXTREME_RS14595
uniprot id: M0L2F1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

358396:CHINAEXTREME RS20040
gene id: 358396:CHINAEXTREME_RS20040
uniprot id: A0A1P8LWG6
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

358396:CHINAEXTREME RS05620
gene id: 358396:CHINAEXTREME_RS05620
uniprot id: M0LMV2
names: Similarity
messages: Belongs to the peptidase S9C family.

358396:CHINAEXTREME RS16465
gene id: 358396:CHINAEXTREME_RS16465
uniprot id: M0LEH8
names: Similarity
messages: Belongs to the HerA family.

358396:CHINAEXTREME RS13875
gene id: 358396:CHINAEXTREME_RS13875
uniprot id: M0LJW4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L24e, part of which may contact the 16S rRNA in 2 intersubunit bridges.

358396:CHINAEXTREME RS12095
gene id: 358396:CHINAEXTREME_RS12095
uniprot id: M0LMJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

358396:CHINAEXTREME RS01775
gene id: 358396:CHINAEXTREME_RS01775
uniprot id: M0LI96
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the methylthiotransferase family. CDKAL1 subfamily.
messages: Binds 1 or 2 [4Fe-4S] cluster. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-threonylcarbamoyladenosine (t(6)A), leading to the formation of 2-methylthio-N6-threonylcarbamoyladenosine (ms(2)t(6)A) at position 37 in tRNAs that read codons beginning with adenine.

358396:CHINAEXTREME RS10245
gene id: 358396:CHINAEXTREME_RS10245
uniprot id: M0L3K3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

358396:CHINAEXTREME RS09810
gene id: 358396:CHINAEXTREME_RS09810
uniprot id: M0L674
names: Function
names: Similarity
names: Subunit
messages: Belongs to the archaeal phosphopantothenate synthetase family.
messages: Catalyzes the condensation of (R)-4-phosphopantoate and beta-alanine to 4'-phosphopantothenate in the CoA biosynthesis pathway.
messages: Homodimer.

358396:CHINAEXTREME RS13170
gene id: 358396:CHINAEXTREME_RS13170
uniprot id: M0LG23
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

358396:CHINAEXTREME RS19015
gene id: 358396:CHINAEXTREME_RS19015
uniprot id: M0LUQ1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

358396:CHINAEXTREME RS20105
gene id: 358396:CHINAEXTREME_RS20105
uniprot id: M0LTZ6
names: Similarity
messages: Belongs to the complex I 20 kDa subunit family.

358396:CHINAEXTREME RS02375
gene id: 358396:CHINAEXTREME_RS02375
uniprot id: M0LEQ6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.

358396:CHINAEXTREME RS13495
gene id: 358396:CHINAEXTREME_RS13495
uniprot id: M0LG68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

358396:CHINAEXTREME RS06975
gene id: 358396:CHINAEXTREME_RS06975
uniprot id: M0LVA6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mer family.
messages: Catalyzes the oxidation of methyl-H(4)MPT to methylene-H(4)MPT.
messages: Cytoplasm

358396:CHINAEXTREME RS07985
gene id: 358396:CHINAEXTREME_RS07985
uniprot id: M0LYY0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 2 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

358396:CHINAEXTREME RS06520
gene id: 358396:CHINAEXTREME_RS06520
uniprot id: A0A1P8LNT7
names: Function
names: Similarity
messages: Belongs to the V-ATPase D subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

358396:CHINAEXTREME RS13710
gene id: 358396:CHINAEXTREME_RS13710
uniprot id: M0LGQ2
names: Similarity
messages: Belongs to the Dps family.

358396:CHINAEXTREME RS10080
gene id: 358396:CHINAEXTREME_RS10080
uniprot id: M0L6P1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

358396:CHINAEXTREME RS03765
gene id: 358396:CHINAEXTREME_RS03765
uniprot id: M0LRH2
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.

358396:CHINAEXTREME RS20115
gene id: 358396:CHINAEXTREME_RS20115
uniprot id: M0LQN4
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

358396:CHINAEXTREME RS19195
gene id: 358396:CHINAEXTREME_RS19195
uniprot id: M0LSF1
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

358396:CHINAEXTREME RS04985
gene id: 358396:CHINAEXTREME_RS04985
uniprot id: M0LPP9
names: Subcellular Location Annotation
messages: Membrane

358396:CHINAEXTREME RS09160
gene id: 358396:CHINAEXTREME_RS09160
uniprot id: M0L7Q5
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the archaeal riboflavin kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

358396:CHINAEXTREME RS17340
gene id: 358396:CHINAEXTREME_RS17340
uniprot id: M0LDA5
names: Similarity
messages: Belongs to the peptidase M24B family.

358396:CHINAEXTREME RS07415
gene id: 358396:CHINAEXTREME_RS07415
uniprot id: M0LXF6
names: Subcellular Location Annotation
messages: Membrane

358396:CHINAEXTREME RS02055
gene id: 358396:CHINAEXTREME_RS02055
uniprot id: M0LI46
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

358396:CHINAEXTREME RS12215
gene id: 358396:CHINAEXTREME_RS12215
uniprot id: M0LJN2
names: Subcellular Location Annotation
messages: Membrane

358396:CHINAEXTREME RS05655
gene id: 358396:CHINAEXTREME_RS05655
uniprot id: M0LJU2
names: Subcellular Location Annotation
messages: Membrane

358396:CHINAEXTREME RS02240
gene id: 358396:CHINAEXTREME_RS02240
uniprot id: M0LI18
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase IV family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin.
messages: Homodimer.

358396:CHINAEXTREME RS08610
gene id: 358396:CHINAEXTREME_RS08610
uniprot id: M0LVA3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

358396:CHINAEXTREME RS19970
gene id: 358396:CHINAEXTREME_RS19970
uniprot id: M0LQY6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the XPG/RAD2 endonuclease family. FEN1 subfamily.
messages: Binds 2 magnesium ions per subunit. They probably participate in the reaction catalyzed by the enzyme. May bind an additional third magnesium ion after substrate binding.
messages: Interacts with PCNA. PCNA stimulates the nuclease activity without altering cleavage specificity.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. Acts as a genome stabilization factor that prevents flaps from equilibrating into structures that lead to duplications and deletions. Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA.
messages: Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. Acts as a genome stabilization factor that prevents flaps from equilibrating into structurs that lead to duplications and deletions. Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA.

358396:CHINAEXTREME RS08995
gene id: 358396:CHINAEXTREME_RS08995
uniprot id: M0L7V5
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

358396:CHINAEXTREME RS18980
gene id: 358396:CHINAEXTREME_RS18980
uniprot id: M0LRJ6
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

358396:CHINAEXTREME RS12280
gene id: 358396:CHINAEXTREME_RS12280
uniprot id: M0LI32
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

358396:CHINAEXTREME RS07395
gene id: 358396:CHINAEXTREME_RS07395
uniprot id: M0LV48
names: Function
names: Similarity
messages: Belongs to the CDC6/cdc18 family.
messages: Involved in regulation of DNA replication.

358396:CHINAEXTREME RS10850
gene id: 358396:CHINAEXTREME_RS10850
uniprot id: M0L7C6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

358396:CHINAEXTREME RS01970
gene id: 358396:CHINAEXTREME_RS01970
uniprot id: M0LJC5
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family.

358396:CHINAEXTREME RS06130
gene id: 358396:CHINAEXTREME_RS06130
uniprot id: A0A1P8LNL0
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

358396:CHINAEXTREME RS01645
gene id: 358396:CHINAEXTREME_RS01645
uniprot id: M0LJI9
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

358396:CHINAEXTREME RS17010
gene id: 358396:CHINAEXTREME_RS17010
uniprot id: M0LQ02
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS1 family.

358396:CHINAEXTREME RS10935
gene id: 358396:CHINAEXTREME_RS10935
uniprot id: M0L2W7
names: Function
names: Subcellular Location Annotation
messages: May play a structural or regulatory role in gas vesicle synthesis.
messages: Vesicle
messages: gas vesicle

358396:CHINAEXTREME RS13255
gene id: 358396:CHINAEXTREME_RS13255
uniprot id: M0LJH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmB/CycW/HelB family.
messages: Membrane

358396:CHINAEXTREME RS04475
gene id: 358396:CHINAEXTREME_RS04475
uniprot id: M0LMQ8
names: Similarity
messages: Belongs to the serine/threonine dehydratase family.

358396:CHINAEXTREME RS15290
gene id: 358396:CHINAEXTREME_RS15290
uniprot id: M0LDX9
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

358396:CHINAEXTREME RS07630
gene id: 358396:CHINAEXTREME_RS07630
uniprot id: M0LU38
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

358396:CHINAEXTREME RS11170
gene id: 358396:CHINAEXTREME_RS11170
uniprot id: M0L309
names: Similarity
messages: Belongs to the archease family.

358396:CHINAEXTREME RS03740
gene id: 358396:CHINAEXTREME_RS03740
uniprot id: M0LRG8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Forms a complex with TatA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.

358396:CHINAEXTREME RS04775
gene id: 358396:CHINAEXTREME_RS04775
uniprot id: M0LLL3
names: Subcellular Location Annotation
messages: Cytoplasm

358396:CHINAEXTREME RS15555
gene id: 358396:CHINAEXTREME_RS15555
uniprot id: M0LFL6
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

358396:CHINAEXTREME RS10265
gene id: 358396:CHINAEXTREME_RS10265
uniprot id: M0L880
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

358396:CHINAEXTREME RS06875
gene id: 358396:CHINAEXTREME_RS06875
uniprot id: M0LU75
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SEC61-beta family.
messages: Cell membrane
messages: Component of the protein translocase complex. Heterotrimer consisting of alpha (SecY), beta (SecG) and gamma (SecE) subunits. Can form oligomers of the heterotrimer.
messages: Involved in protein export. The function of the beta subunit is unknown, but it may be involved in stabilization of the trimeric complex.
messages: Membrane

358396:CHINAEXTREME RS19655
gene id: 358396:CHINAEXTREME_RS19655
uniprot id: M0LUA8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

358396:CHINAEXTREME RS04970
gene id: 358396:CHINAEXTREME_RS04970
uniprot id: M0LK63
names: Function
names: Similarity
messages: Belongs to the Thz kinase family.
messages: Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).

358396:CHINAEXTREME RS11955
gene id: 358396:CHINAEXTREME_RS11955
uniprot id: M0LI44
names: Similarity
messages: Belongs to the asparaginase 1 family.

358396:CHINAEXTREME RS08530
gene id: 358396:CHINAEXTREME_RS08530
uniprot id: M0LYK2
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

358396:CHINAEXTREME RS07160
gene id: 358396:CHINAEXTREME_RS07160
uniprot id: M0LY79
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

358396:CHINAEXTREME RS04680
gene id: 358396:CHINAEXTREME_RS04680
uniprot id: M0LLJ0
names: Function
names: Similarity
messages: Belongs to the TFIIB family.
messages: Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB).

358396:CHINAEXTREME RS07970
gene id: 358396:CHINAEXTREME_RS07970
uniprot id: M0LVF5
names: Subcellular Location Annotation
messages: Membrane

358396:CHINAEXTREME RS02475
gene id: 358396:CHINAEXTREME_RS02475
uniprot id: A0A1P8LLQ5
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

358396:CHINAEXTREME RS02005
gene id: 358396:CHINAEXTREME_RS02005
uniprot id: M0LG91
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

358396:CHINAEXTREME RS07465
gene id: 358396:CHINAEXTREME_RS07465
uniprot id: M0LV26
names: Subcellular Location Annotation
messages: Membrane

358396:CHINAEXTREME RS00505
gene id: 358396:CHINAEXTREME_RS00505
uniprot id: M0L2S3
names: Similarity
messages: Belongs to the pyruvate kinase family.
messages: In the C-terminal section; belongs to the PEP-utilizing enzyme family.

358396:CHINAEXTREME RS20665
gene id: 358396:CHINAEXTREME_RS20665
uniprot id: A0A1P8LWQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

358396:CHINAEXTREME RS17575
gene id: 358396:CHINAEXTREME_RS17575
uniprot id: M0LEQ8
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SMC family. RAD50 subfamily.
messages: Binds 1 zinc ion per homodimer.
messages: Homodimer. Forms a heterotetramer composed of two Mre11 subunits and two Rad50 subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. Rad50 controls the balance between DNA end bridging and DNA resection via ATP-dependent structural rearrangements of the Rad50/Mre11 complex.
messages: The two conserved Cys that bind zinc constitute the zinc-hook, which separates the large intramolecular coiled coil regions. The 2 Cys residues coordinate one molecule of zinc with the help of the 2 Cys residues of the zinc-hook of another Rad50 molecule, thereby forming a V-shaped homodimer.

358396:CHINAEXTREME RS15570
gene id: 358396:CHINAEXTREME_RS15570
uniprot id: M0LCD1
names: Subcellular Location Annotation
messages: Membrane

358396:CHINAEXTREME RS03190
gene id: 358396:CHINAEXTREME_RS03190
uniprot id: M0LNH4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
messages: Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.
messages: Cytoplasm

358396:CHINAEXTREME RS04745
gene id: 358396:CHINAEXTREME_RS04745
uniprot id: M0LLR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

358396:CHINAEXTREME RS06535
gene id: 358396:CHINAEXTREME_RS06535
uniprot id: M0LYJ5
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit.

358396:CHINAEXTREME RS06460
gene id: 358396:CHINAEXTREME_RS06460
uniprot id: A0A1P8LW69
names: Caution
names: Function
names: Similarity
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

358396:CHINAEXTREME RS07060
gene id: 358396:CHINAEXTREME_RS07060
uniprot id: M0LY96
names: Subcellular Location Annotation
messages: Membrane

358396:CHINAEXTREME RS00720
gene id: 358396:CHINAEXTREME_RS00720
uniprot id: M0LHE2
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

358396:CHINAEXTREME RS06540
gene id: 358396:CHINAEXTREME_RS06540
uniprot id: M0LXD6
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit.

358396:CHINAEXTREME RS19730
gene id: 358396:CHINAEXTREME_RS19730
uniprot id: M0LU89
names: Similarity
messages: Belongs to the methylamine corrinoid protein family.

358396:CHINAEXTREME RS05795
gene id: 358396:CHINAEXTREME_RS05795
uniprot id: M0LMY4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

358396:CHINAEXTREME RS11315
gene id: 358396:CHINAEXTREME_RS11315
uniprot id: M0L679
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

358396:CHINAEXTREME RS14080
gene id: 358396:CHINAEXTREME_RS14080
uniprot id: M0LIS5
names: Similarity
messages: Belongs to the LarC family.

358396:CHINAEXTREME RS20065
gene id: 358396:CHINAEXTREME_RS20065
uniprot id: M0LQP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

358396:CHINAEXTREME RS18760
gene id: 358396:CHINAEXTREME_RS18760
uniprot id: M0LSL3
names: Function
names: Similarity
messages: Belongs to the CheD family.
messages: Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.

358396:CHINAEXTREME RS17715
gene id: 358396:CHINAEXTREME_RS17715
uniprot id: M0LDG8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease gamma subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

358396:CHINAEXTREME RS14610
gene id: 358396:CHINAEXTREME_RS14610
uniprot id: M0L5K7
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

358396:CHINAEXTREME RS07190
gene id: 358396:CHINAEXTREME_RS07190
uniprot id: M0LXJ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS19 family.
messages: May be involved in maturation of the 30S ribosomal subunit.
messages: Part of the 30S ribosomal subunit.

358396:CHINAEXTREME RS08060
gene id: 358396:CHINAEXTREME_RS08060
uniprot id: A0A1P8LPK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

358396:CHINAEXTREME RS11280
gene id: 358396:CHINAEXTREME_RS11280
uniprot id: M0L327
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

358396:CHINAEXTREME RS16475
gene id: 358396:CHINAEXTREME_RS16475
uniprot id: M0LB86
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

358396:CHINAEXTREME RS16340
gene id: 358396:CHINAEXTREME_RS16340
uniprot id: M0LCG5
names: Similarity
names: Subunit
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Homohexamer.

358396:CHINAEXTREME RS05055
gene id: 358396:CHINAEXTREME_RS05055
uniprot id: M0LNI2
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

358396:CHINAEXTREME RS06885
gene id: 358396:CHINAEXTREME_RS06885
uniprot id: M0LUI4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glutaminase PdxT/SNO family.
messages: Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
messages: In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer.

358396:CHINAEXTREME RS04990
gene id: 358396:CHINAEXTREME_RS04990
uniprot id: M0LKE8
names: Subcellular Location Annotation
messages: Membrane

358396:CHINAEXTREME RS10485
gene id: 358396:CHINAEXTREME_RS10485
uniprot id: M0L6V8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA.
messages: Belongs to the TiaS family.
messages: Cytoplasm

358396:CHINAEXTREME RS06675
gene id: 358396:CHINAEXTREME_RS06675
uniprot id: M0LXS7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic release factor 1 family.
messages: Cytoplasm
messages: Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA.
messages: Heterodimer of two subunits, one of which binds GTP.

358396:CHINAEXTREME RS07635
gene id: 358396:CHINAEXTREME_RS07635
uniprot id: M0LXY6
names: Function
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).

358396:CHINAEXTREME RS08040
gene id: 358396:CHINAEXTREME_RS08040
uniprot id: M0LWL5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

358396:CHINAEXTREME RS02060
gene id: 358396:CHINAEXTREME_RS02060
uniprot id: M0LG80
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the eIF-2B alpha/beta/delta subunits family. R15P isomerase subfamily.
messages: Catalyzes the isomerization of ribose 1,5-bisphosphate (R15P) to ribulose 1,5-bisphosphate (RuBP), the CO(2) acceptor and substrate for RubisCO. Functions in an archaeal AMP degradation pathway, together with AMP phosphorylase and RubisCO.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds via a cis-phosphoenolate intermediate.

358396:CHINAEXTREME RS10930
gene id: 358396:CHINAEXTREME_RS10930
uniprot id: M0L7D8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gas vesicle protein type A family.
messages: Gas vesicles are small, hollow, gas filled protein structures that are found in several microbial planktonic microorganisms. They allow the positioning of the organism at the favorable depth for growth. GvpA type proteins form the essential core of the structure.
messages: gas vesicle membrane

358396:CHINAEXTREME RS19220
gene id: 358396:CHINAEXTREME_RS19220
uniprot id: M0LSE9
names: Similarity
messages: Belongs to the DeoC/FbaB aldolase family.

358396:CHINAEXTREME RS02810
gene id: 358396:CHINAEXTREME_RS02810
uniprot id: M0LRI9
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A single active site specifically recognizes both ATP and CTP and is responsible for their addition.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Archaeal CCA-adding enzyme subfamily.
messages: Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.
messages: Homodimer.

358396:CHINAEXTREME RS13890
gene id: 358396:CHINAEXTREME_RS13890
uniprot id: M0LGT9
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

358396:CHINAEXTREME RS09795
gene id: 358396:CHINAEXTREME_RS09795
uniprot id: M0L9L5
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

358396:CHINAEXTREME RS08315
gene id: 358396:CHINAEXTREME_RS08315
uniprot id: M0LVH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal/bacterial/fungal opsin family.
messages: Membrane

358396:CHINAEXTREME RS14410
gene id: 358396:CHINAEXTREME_RS14410
uniprot id: M0L5F4
names: Similarity
messages: Belongs to the UPF0175 family.

358396:CHINAEXTREME RS08085
gene id: 358396:CHINAEXTREME_RS08085
uniprot id: M0LYW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM19 family.
messages: Membrane

358396:CHINAEXTREME RS13570
gene id: 358396:CHINAEXTREME_RS13570
uniprot id: M0LII0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. Probably involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Probably involved in E site tRNA release (By similarity). Binds directly to 23S rRNA.
messages: Protein L1 is also a translational repressor protein, it controls the translation of its operon by binding to its mRNA.

358396:CHINAEXTREME RS16655
gene id: 358396:CHINAEXTREME_RS16655
uniprot id: M0LCN7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

358396:CHINAEXTREME RS02310
gene id: 358396:CHINAEXTREME_RS02310
uniprot id: M0LJ74
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Forms part of the jaw domain.
messages: Part of the RNA polymerase complex.

358396:CHINAEXTREME RS10095
gene id: 358396:CHINAEXTREME_RS10095
uniprot id: M0L3D9
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

358396:CHINAEXTREME RS02150
gene id: 358396:CHINAEXTREME_RS02150
uniprot id: M0LJ98
names: Subcellular Location Annotation
messages: Membrane

358396:CHINAEXTREME RS02355
gene id: 358396:CHINAEXTREME_RS02355
uniprot id: M0LER2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center.
messages: Part of the 30S ribosomal subunit.

358396:CHINAEXTREME RS19595
gene id: 358396:CHINAEXTREME_RS19595
uniprot id: M0LV75
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL42 family.
messages: Binds 1 zinc ion per subunit.
messages: Binds to the 23S rRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the 50S ribosomal subunit.

358396:CHINAEXTREME RS03520
gene id: 358396:CHINAEXTREME_RS03520
uniprot id: M0LNB7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

358396:CHINAEXTREME RS19805
gene id: 358396:CHINAEXTREME_RS19805
uniprot id: M0LS54
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

358396:CHINAEXTREME RS06205
gene id: 358396:CHINAEXTREME_RS06205
uniprot id: M0M110
names: Subcellular Location Annotation
messages: Membrane

358396:CHINAEXTREME RS16565
gene id: 358396:CHINAEXTREME_RS16565
uniprot id: M0LFU0
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

358396:CHINAEXTREME RS13950
gene id: 358396:CHINAEXTREME_RS13950
uniprot id: M0LIQ5
names: Similarity
messages: Belongs to the UPF0045 family.

358396:CHINAEXTREME RS11260
gene id: 358396:CHINAEXTREME_RS11260
uniprot id: M0L2Y8
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

358396:CHINAEXTREME RS10790
gene id: 358396:CHINAEXTREME_RS10790
uniprot id: M0L544
names: Similarity
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.

358396:CHINAEXTREME RS07755
gene id: 358396:CHINAEXTREME_RS07755
uniprot id: M0LTQ1
names: Similarity
messages: Belongs to the HAM1 NTPase family.

358396:CHINAEXTREME RS11295
gene id: 358396:CHINAEXTREME_RS11295
uniprot id: M0L7M0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the isopentenyl phosphate kinase family.
messages: Catalyzes the phosphorylation of isopentenyl phosphate (IP) to isopentenyl diphosphate (IPP). Functions in an alternate mevalonate (MVA) pathway leading to IPP, a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids.
messages: Homodimer.

358396:CHINAEXTREME RS07435
gene id: 358396:CHINAEXTREME_RS07435
uniprot id: M0LXF3
names: Similarity
messages: Belongs to the TCP-1 chaperonin family.

358396:CHINAEXTREME RS15690
gene id: 358396:CHINAEXTREME_RS15690
uniprot id: M0LBJ4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DtxR/MntR family.
messages: Cytoplasm
messages: Homodimer.

358396:CHINAEXTREME RS13985
gene id: 358396:CHINAEXTREME_RS13985
uniprot id: M0LFJ1
names: Similarity
messages: Belongs to the OMP decarboxylase family. Type 2 subfamily.

358396:CHINAEXTREME RS12925
gene id: 358396:CHINAEXTREME_RS12925
uniprot id: M0LFY9
names: Similarity
messages: Belongs to the SCO1/2 family.

358396:CHINAEXTREME RS05775
gene id: 358396:CHINAEXTREME_RS05775
uniprot id: M0LP60
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA-intron endonuclease family. Archaeal long subfamily.
messages: Endonuclease that removes tRNA introns. Cleaves pre-tRNA at the 5' and 3' splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp.
messages: Endonuclease that removes tRNA introns. Cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp.
messages: Homodimer.

358396:CHINAEXTREME RS07795
gene id: 358396:CHINAEXTREME_RS07795
uniprot id: M0LX54
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS24 family.

358396:CHINAEXTREME RS11035
gene id: 358396:CHINAEXTREME_RS11035
uniprot id: M0L2Y5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Belongs to the inositol monophosphatase superfamily.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

358396:CHINAEXTREME RS13740
gene id: 358396:CHINAEXTREME_RS13740
uniprot id: M0LIL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Membrane

358396:CHINAEXTREME RS14715
gene id: 358396:CHINAEXTREME_RS14715
uniprot id: M0L5J0
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

358396:CHINAEXTREME RS10510
gene id: 358396:CHINAEXTREME_RS10510
uniprot id: M0L6W1
names: Subcellular Location Annotation
messages: Membrane

358396:CHINAEXTREME RS15935
gene id: 358396:CHINAEXTREME_RS15935
uniprot id: M0LC80
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

358396:CHINAEXTREME RS12510
gene id: 358396:CHINAEXTREME_RS12510
uniprot id: M0LM22
names: Function
names: Similarity
messages: Belongs to the adenylate cyclase family. DacZ subfamily.
messages: Diadenylate cyclase that catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP is a second messenger for intracellular signal transduction involved in the control of important regulatory processes such as osmoregulation.

358396:CHINAEXTREME RS00245
gene id: 358396:CHINAEXTREME_RS00245
uniprot id: M0LT85
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

358396:CHINAEXTREME RS10765
gene id: 358396:CHINAEXTREME_RS10765
uniprot id: M0L539
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

358396:CHINAEXTREME RS03360
gene id: 358396:CHINAEXTREME_RS03360
uniprot id: M0LS56
names: Caution
names: Function
names: Similarity
messages: Belongs to the TFIIB family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB).

358396:CHINAEXTREME RS13900
gene id: 358396:CHINAEXTREME_RS13900
uniprot id: M0LJX0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

358396:CHINAEXTREME RS04980
gene id: 358396:CHINAEXTREME_RS04980
uniprot id: M0LNG2
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. S-2-haloalkanoic acid dehalogenase family.

358396:CHINAEXTREME RS21490
gene id: 358396:CHINAEXTREME_RS21490
uniprot id: M0LG51
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

358396:CHINAEXTREME RS14925
gene id: 358396:CHINAEXTREME_RS14925
uniprot id: M0LE06
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate.
messages: Belongs to the GatB/GatE family. GatE subfamily.
messages: Heterodimer of GatD and GatE.

358396:CHINAEXTREME RS10175
gene id: 358396:CHINAEXTREME_RS10175
uniprot id: M0L3F5
names: Subcellular Location Annotation
messages: Membrane

358396:CHINAEXTREME RS10145
gene id: 358396:CHINAEXTREME_RS10145
uniprot id: M0L3I4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SPT5 family.
messages: Belongs to the archaeal Spt5 family.
messages: Heterodimer composed of Spt4 and Spt5. Interacts with RNA polymerase (RNAP).
messages: Stimulates transcription elongation.

358396:CHINAEXTREME RS02395
gene id: 358396:CHINAEXTREME_RS02395
uniprot id: M0LEL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC41A transporter family.
messages: Membrane

358396:CHINAEXTREME RS16260
gene id: 358396:CHINAEXTREME_RS16260
uniprot id: M0LCF0
names: Subcellular Location Annotation
messages: Membrane

358396:CHINAEXTREME RS01405
gene id: 358396:CHINAEXTREME_RS01405
uniprot id: A0A1P8LL57
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-I 3-dehydroquinase family.
messages: Homodimer.
messages: Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

358396:CHINAEXTREME RS00770
gene id: 358396:CHINAEXTREME_RS00770
uniprot id: A0A1P8LKR8
names: Function
messages: Part of a potassium transport system.

358396:CHINAEXTREME RS15610
gene id: 358396:CHINAEXTREME_RS15610
uniprot id: M0LGW6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

358396:CHINAEXTREME RS12760
gene id: 358396:CHINAEXTREME_RS12760
uniprot id: M0LJ42
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

358396:CHINAEXTREME RS15685
gene id: 358396:CHINAEXTREME_RS15685
uniprot id: M0LBI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NADH dehydrogenase family.
messages: Cytoplasm

358396:CHINAEXTREME RS17805
gene id: 358396:CHINAEXTREME_RS17805
uniprot id: M0LDG7
names: Similarity
messages: Belongs to the UPF0179 family.

358396:CHINAEXTREME RS00645
gene id: 358396:CHINAEXTREME_RS00645
uniprot id: M0L1E1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

358396:CHINAEXTREME RS09475
gene id: 358396:CHINAEXTREME_RS09475
uniprot id: M0L4S7
names: Similarity
messages: Belongs to the UPF0173 family.

358396:CHINAEXTREME RS16175
gene id: 358396:CHINAEXTREME_RS16175
uniprot id: M0LFL7
names: Similarity
messages: Belongs to the SDO1/SBDS family.

358396:CHINAEXTREME RS13830
gene id: 358396:CHINAEXTREME_RS13830
uniprot id: M0LFF9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

358396:CHINAEXTREME RS10320
gene id: 358396:CHINAEXTREME_RS10320
uniprot id: M0L3L9
names: Function
messages: Part of a potassium transport system.

358396:CHINAEXTREME RS13865
gene id: 358396:CHINAEXTREME_RS13865
uniprot id: M0LGT4
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS4 family.

358396:CHINAEXTREME RS00475
gene id: 358396:CHINAEXTREME_RS00475
uniprot id: A0A1P8LKL5
names: Similarity
messages: Belongs to the peptidase S49 family.

358396:CHINAEXTREME RS20070
gene id: 358396:CHINAEXTREME_RS20070
uniprot id: M0LQW7
names: Subcellular Location Annotation
messages: Membrane

358396:CHINAEXTREME RS12435
gene id: 358396:CHINAEXTREME_RS12435
uniprot id: M0LHR4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

358396:CHINAEXTREME RS19725
gene id: 358396:CHINAEXTREME_RS19725
uniprot id: M0LV43
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

358396:CHINAEXTREME RS17720
gene id: 358396:CHINAEXTREME_RS17720
uniprot id: M0LET6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
messages: Cytoplasm
messages: Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
messages: Homodimer. UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

358396:CHINAEXTREME RS07075
gene id: 358396:CHINAEXTREME_RS07075
uniprot id: M0LU43
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic RPB7/RPC8 RNA polymerase subunit family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Forms 2 domains with an elongated structure; Rpo4 packs into the hinge region between the 2 domains.
messages: Nucleus
messages: Part of the RNA polymerase complex. Forms a stalk with Rpo4 that extends from the main structure.

358396:CHINAEXTREME RS00275
gene id: 358396:CHINAEXTREME_RS00275
uniprot id: A0A1P8LKH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

358396:CHINAEXTREME RS12160
gene id: 358396:CHINAEXTREME_RS12160
uniprot id: M0LI04
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

358396:CHINAEXTREME RS02960
gene id: 358396:CHINAEXTREME_RS02960
uniprot id: A0A1P8LLX3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

358396:CHINAEXTREME RS12595
gene id: 358396:CHINAEXTREME_RS12595
uniprot id: M0LHU0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
messages: Cytoplasm
messages: The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped at one or both ends by the proteasome regulatory ATPase, PAN.

358396:CHINAEXTREME RS17420
gene id: 358396:CHINAEXTREME_RS17420
uniprot id: A0A1P8LUG7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. DGGGP synthase subfamily.
messages: Cell membrane
messages: Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids.

358396:CHINAEXTREME RS07700
gene id: 358396:CHINAEXTREME_RS07700
uniprot id: M0LTR0
names: Subcellular Location Annotation
messages: Membrane

358396:CHINAEXTREME RS12690
gene id: 358396:CHINAEXTREME_RS12690
uniprot id: M0LKA1
names: Subcellular Location Annotation
messages: Membrane

358396:CHINAEXTREME RS00955
gene id: 358396:CHINAEXTREME_RS00955
uniprot id: M0LE29
names: Subcellular Location Annotation
messages: Membrane

358396:CHINAEXTREME RS02305
gene id: 358396:CHINAEXTREME_RS02305
uniprot id: M0LES2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds at least 2 Zn(2+) per subunit.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Forms the clamp head domain.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

358396:CHINAEXTREME RS14820
gene id: 358396:CHINAEXTREME_RS14820
uniprot id: M0LAE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

358396:CHINAEXTREME RS08550
gene id: 358396:CHINAEXTREME_RS08550
uniprot id: A0A1P8LPW7
names: Subcellular Location Annotation
messages: Membrane

358396:CHINAEXTREME RS01230
gene id: 358396:CHINAEXTREME_RS01230
uniprot id: M0LDU1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

358396:CHINAEXTREME RS08010
gene id: 358396:CHINAEXTREME_RS08010
uniprot id: M0LYX6
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

358396:CHINAEXTREME RS09610
gene id: 358396:CHINAEXTREME_RS09610
uniprot id: M0L643
names: Subcellular Location Annotation
messages: Membrane

358396:CHINAEXTREME RS12530
gene id: 358396:CHINAEXTREME_RS12530
uniprot id: M0LKY2
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

358396:CHINAEXTREME RS17475
gene id: 358396:CHINAEXTREME_RS17475
uniprot id: M0LDC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

358396:CHINAEXTREME RS08305
gene id: 358396:CHINAEXTREME_RS08305
uniprot id: M0LWE8
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

358396:CHINAEXTREME RS03235
gene id: 358396:CHINAEXTREME_RS03235
uniprot id: M0LMY8
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

358396:CHINAEXTREME RS17705
gene id: 358396:CHINAEXTREME_RS17705
uniprot id: M0LHY9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease beta subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

358396:CHINAEXTREME RS04690
gene id: 358396:CHINAEXTREME_RS04690
uniprot id: M0LPP5
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

358396:CHINAEXTREME RS09150
gene id: 358396:CHINAEXTREME_RS09150
uniprot id: M0L4I5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TYW1 family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Component of the wyosine derivatives biosynthesis pathway that catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine (imG-14) on guanosine-37 of tRNA(Phe).
messages: Cytoplasm
messages: Monomer.

358396:CHINAEXTREME RS19775
gene id: 358396:CHINAEXTREME_RS19775
uniprot id: A0A1P8LWI9
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

358396:CHINAEXTREME RS21110
gene id: 358396:CHINAEXTREME_RS21110
uniprot id: M0LA75
names: Function
names: Similarity
messages: Belongs to the TFIIB family.
messages: Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB).

358396:CHINAEXTREME RS16310
gene id: 358396:CHINAEXTREME_RS16310
uniprot id: M0LB66
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.

358396:CHINAEXTREME RS05490
gene id: 358396:CHINAEXTREME_RS05490
uniprot id: M0LL12
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

358396:CHINAEXTREME RS12430
gene id: 358396:CHINAEXTREME_RS12430
uniprot id: M0LM11
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

358396:CHINAEXTREME RS05435
gene id: 358396:CHINAEXTREME_RS05435
uniprot id: M0LJE2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

358396:CHINAEXTREME RS18800
gene id: 358396:CHINAEXTREME_RS18800
uniprot id: A0A1P8LV57
names: Subcellular Location Annotation
messages: Membrane

358396:CHINAEXTREME RS05385
gene id: 358396:CHINAEXTREME_RS05385
uniprot id: M0LNP4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane
messages: Potential transporter for phosphate.

358396:CHINAEXTREME RS15740
gene id: 358396:CHINAEXTREME_RS15740
uniprot id: M0LBK4
names: Function
names: Similarity
messages: Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.
messages: Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC), the main low-molecular-weight thiol compound instead of glutathione in halophilic archaea.

358396:CHINAEXTREME RS20075
gene id: 358396:CHINAEXTREME_RS20075
uniprot id: M0LUX1
names: Subcellular Location Annotation
messages: Membrane

358396:CHINAEXTREME RS10965
gene id: 358396:CHINAEXTREME_RS10965
uniprot id: M0L2S9
names: Function
names: Subcellular Location Annotation
messages: May play a structural or regulatory role in gas vesicle synthesis.
messages: Vesicle
messages: gas vesicle

358396:CHINAEXTREME RS08145
gene id: 358396:CHINAEXTREME_RS08145
uniprot id: M0LVC0
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

358396:CHINAEXTREME RS20100
gene id: 358396:CHINAEXTREME_RS20100
uniprot id: M0LUW7
names: Similarity
messages: In the C-terminal section; belongs to the complex I 49 kDa subunit family.

358396:CHINAEXTREME RS03185
gene id: 358396:CHINAEXTREME_RS03185
uniprot id: M0LNN5
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
messages: Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.

358396:CHINAEXTREME RS07260
gene id: 358396:CHINAEXTREME_RS07260
uniprot id: M0LY61
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M32 family.
messages: Binds 1 zinc ion per subunit.
messages: Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues.

358396:CHINAEXTREME RS02290
gene id: 358396:CHINAEXTREME_RS02290
uniprot id: M0LI08
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal Rpo5/eukaryotic RPB5 RNA polymerase subunit family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

358396:CHINAEXTREME RS07605
gene id: 358396:CHINAEXTREME_RS07605
uniprot id: M0LU45
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA 3'-terminal cyclase family. Type 1 subfamily.
messages: Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing.
messages: Cytoplasm

358396:CHINAEXTREME RS14935
gene id: 358396:CHINAEXTREME_RS14935
uniprot id: M0LAN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

358396:CHINAEXTREME RS02265
gene id: 358396:CHINAEXTREME_RS02265
uniprot id: M0LI13
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

358396:CHINAEXTREME RS13450
gene id: 358396:CHINAEXTREME_RS13450
uniprot id: M0LHN9
names: Similarity
messages: Belongs to the helicase family. RAD25/XPB subfamily.

358396:CHINAEXTREME RS10460
gene id: 358396:CHINAEXTREME_RS10460
uniprot id: M0L6V4
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

358396:CHINAEXTREME RS10960
gene id: 358396:CHINAEXTREME_RS10960
uniprot id: M0L2X1
names: Function
names: Subcellular Location Annotation
messages: May play a structural or regulatory role in gas vesicle synthesis.
messages: Vesicle
messages: gas vesicle

358396:CHINAEXTREME RS19300
gene id: 358396:CHINAEXTREME_RS19300
uniprot id: M0LR33
names: Similarity
names: Subunit
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Homohexamer.

358396:CHINAEXTREME RS07360
gene id: 358396:CHINAEXTREME_RS07360
uniprot id: M0LY50
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M54 family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic, whereas the other seems to have a structural role.
messages: Monomer.
messages: Probable zinc metalloprotease whose natural substrate is unknown.

358396:CHINAEXTREME RS03785
gene id: 358396:CHINAEXTREME_RS03785
uniprot id: M0LQC9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic-type primase large subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Heterodimer of a small subunit (PriS) and a large subunit (PriL).
messages: Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair.

358396:CHINAEXTREME RS06225
gene id: 358396:CHINAEXTREME_RS06225
uniprot id: M0M1N6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Archaeal flagellum
messages: Belongs to the archaeal flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of archaeal flagella.

358396:CHINAEXTREME RS18505
gene id: 358396:CHINAEXTREME_RS18505
uniprot id: M0LR60
names: Subcellular Location Annotation
messages: Cytoplasm

358396:CHINAEXTREME RS10970
gene id: 358396:CHINAEXTREME_RS10970
uniprot id: M0L473
names: Function
names: Similarity
messages: Belongs to the gas vesicle protein type A family.
messages: Gas vesicles are small, hollow, gas filled protein structures that are found in several microbial planktonic microorganisms. They allow the positioning of the organism at the favorable depth for growth.

358396:CHINAEXTREME RS05270
gene id: 358396:CHINAEXTREME_RS05270
uniprot id: M0LKJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal/bacterial/fungal opsin family.
messages: Membrane

358396:CHINAEXTREME RS00005
gene id: 358396:CHINAEXTREME_RS00005
uniprot id: M0LVM5
names: Similarity
messages: Belongs to the TPP enzyme family.

358396:CHINAEXTREME RS17000
gene id: 358396:CHINAEXTREME_RS17000
uniprot id: M0LSW0
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruD family.
messages: Could be responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.

358396:CHINAEXTREME RS09440
gene id: 358396:CHINAEXTREME_RS09440
uniprot id: M0L7W0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

358396:CHINAEXTREME RS06550
gene id: 358396:CHINAEXTREME_RS06550
uniprot id: M0M1H5
names: Function
names: Similarity
messages: Belongs to the V-ATPase V0D/AC39 subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

358396:CHINAEXTREME RS11370
gene id: 358396:CHINAEXTREME_RS11370
uniprot id: M0L690
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL8 family.
messages: Cytoplasm
messages: Multifunctional RNA-binding protein that recognizes the K-turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs.
messages: Part of the 50S ribosomal subunit. Probably part of the RNase P complex.

358396:CHINAEXTREME RS14540
gene id: 358396:CHINAEXTREME_RS14540
uniprot id: M0L2G1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

358396:CHINAEXTREME RS19675
gene id: 358396:CHINAEXTREME_RS19675
uniprot id: M0LV57
names: Function
names: Similarity
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. Archaeal HPRT subfamily.
messages: May catalyze a purine salvage reaction, the substrate is unknown.

358396:CHINAEXTREME RS03085
gene id: 358396:CHINAEXTREME_RS03085
uniprot id: A0A1P8LLZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane

358396:CHINAEXTREME RS04005
gene id: 358396:CHINAEXTREME_RS04005
uniprot id: M0LQH4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the archaeal DNA polymerase II family.
messages: Heterodimer of a large subunit and a small subunit.
messages: Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase.

358396:CHINAEXTREME RS04385
gene id: 358396:CHINAEXTREME_RS04385
uniprot id: M0LNT5
names: Subcellular Location Annotation
messages: Membrane

358396:CHINAEXTREME RS12035
gene id: 358396:CHINAEXTREME_RS12035
uniprot id: M0LJJ4
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

358396:CHINAEXTREME RS13175
gene id: 358396:CHINAEXTREME_RS13175
uniprot id: M0LHJ7
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

358396:CHINAEXTREME RS10570
gene id: 358396:CHINAEXTREME_RS10570
uniprot id: M0L3S0
names: Subcellular Location Annotation
messages: Membrane

358396:CHINAEXTREME RS17545
gene id: 358396:CHINAEXTREME_RS17545
uniprot id: M0LDC0
names: Subunit
messages: Homotetramer.

358396:CHINAEXTREME RS15235
gene id: 358396:CHINAEXTREME_RS15235
uniprot id: M0LCL2
names: Caution
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
messages: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

358396:CHINAEXTREME RS17390
gene id: 358396:CHINAEXTREME_RS17390
uniprot id: M0LDB4
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

358396:CHINAEXTREME RS16825
gene id: 358396:CHINAEXTREME_RS16825
uniprot id: M0LSY9
names: Subcellular Location Annotation
messages: Membrane

358396:CHINAEXTREME RS13655
gene id: 358396:CHINAEXTREME_RS13655
uniprot id: M0LFC2
names: Similarity
messages: Belongs to the peptidase S66 family.

358396:CHINAEXTREME RS04135
gene id: 358396:CHINAEXTREME_RS04135
uniprot id: M0LRP2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

358396:CHINAEXTREME RS14530
gene id: 358396:CHINAEXTREME_RS14530
uniprot id: M0L269
names: Subcellular Location Annotation
messages: Membrane

358396:CHINAEXTREME RS03225
gene id: 358396:CHINAEXTREME_RS03225
uniprot id: M0LQZ4
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

358396:CHINAEXTREME RS02745
gene id: 358396:CHINAEXTREME_RS02745
uniprot id: M0LPL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

358396:CHINAEXTREME RS00100
gene id: 358396:CHINAEXTREME_RS00100
uniprot id: M0LWC6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycerol-1-phosphate dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea.
messages: Cytoplasm

358396:CHINAEXTREME RS20545
gene id: 358396:CHINAEXTREME_RS20545
uniprot id: M0LYE9
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

358396:CHINAEXTREME RS08900
gene id: 358396:CHINAEXTREME_RS08900
uniprot id: M0LB31
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

358396:CHINAEXTREME RS14760
gene id: 358396:CHINAEXTREME_RS14760
uniprot id: M0LDN1
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

358396:CHINAEXTREME RS05550
gene id: 358396:CHINAEXTREME_RS05550
uniprot id: M0LP16
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

358396:CHINAEXTREME RS19580
gene id: 358396:CHINAEXTREME_RS19580
uniprot id: M0LS92
names: Function
names: Similarity
messages: Belongs to the NOP10 family.
messages: Involved in ribosome biogenesis; more specifically in 18S rRNA pseudouridylation and in cleavage of pre-rRNA.

358396:CHINAEXTREME RS00325
gene id: 358396:CHINAEXTREME_RS00325
uniprot id: M0L1K6
names: Similarity
messages: Belongs to the TCP-1 chaperonin family.

358396:CHINAEXTREME RS00940
gene id: 358396:CHINAEXTREME_RS00940
uniprot id: M0LII8
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase Pus10 family.
messages: Responsible for synthesis of pseudouridine from uracil-54 and uracil-55 in the psi GC loop of transfer RNAs.

358396:CHINAEXTREME RS12040
gene id: 358396:CHINAEXTREME_RS12040
uniprot id: M0LLB6
names: Subcellular Location Annotation
messages: Endoplasmic reticulum
messages: Golgi apparatus
messages: Lysosome
messages: Secreted

358396:CHINAEXTREME RS17025
gene id: 358396:CHINAEXTREME_RS17025
uniprot id: A0A1P8LU97
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Part of the 30S ribosomal subunit.

358396:CHINAEXTREME RS01955
gene id: 358396:CHINAEXTREME_RS01955
uniprot id: M0LG98
names: Subcellular Location Annotation
messages: Cytoplasm

358396:CHINAEXTREME RS09555
gene id: 358396:CHINAEXTREME_RS09555
uniprot id: M0L4R8
names: Function
names: Similarity
names: Subunit
messages: Associates with stalled 50S ribosomal subunits.
messages: Belongs to the NEMF family.
messages: Probably part of the ribosome quality control system (RQC). May mediate the addition of alanine residues (Ala tailing) to incompletely synthesized nascent chains from stalled ribosomes, leading to their degradation.

358396:CHINAEXTREME RS00035
gene id: 358396:CHINAEXTREME_RS00035
uniprot id: M0LTD5
names: Subcellular Location Annotation
messages: Nucleus

358396:CHINAEXTREME RS10180
gene id: 358396:CHINAEXTREME_RS10180
uniprot id: A0A1P8LQS8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endonuclease V family.
messages: Cytoplasm
messages: DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA.

358396:CHINAEXTREME RS04400
gene id: 358396:CHINAEXTREME_RS04400
uniprot id: A0A1P8LMQ5
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

358396:CHINAEXTREME RS06635
gene id: 358396:CHINAEXTREME_RS06635
uniprot id: A0A1P8LNV1
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

358396:CHINAEXTREME RS10955
gene id: 358396:CHINAEXTREME_RS10955
uniprot id: M0L7E3
names: Function
names: Similarity
messages: Belongs to the gas vesicle protein type A family.
messages: Gas vesicles are small, hollow, gas filled protein structures that are found in several microbial planktonic microorganisms. They allow the positioning of the organism at the favorable depth for growth.

358396:CHINAEXTREME RS02630
gene id: 358396:CHINAEXTREME_RS02630
uniprot id: M0LHR6
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

358396:CHINAEXTREME RS20015
gene id: 358396:CHINAEXTREME_RS20015
uniprot id: M0LQQ4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal/bacterial/fungal opsin family.
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

358396:CHINAEXTREME RS02350
gene id: 358396:CHINAEXTREME_RS02350
uniprot id: M0LEM6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Part of the 30S ribosomal subunit.
messages: With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits.

358396:CHINAEXTREME RS00775
gene id: 358396:CHINAEXTREME_RS00775
uniprot id: M0LFH2
names: Subcellular Location Annotation
messages: Membrane

358396:CHINAEXTREME RS00765
gene id: 358396:CHINAEXTREME_RS00765
uniprot id: M0LIM2
names: Subcellular Location Annotation
messages: Membrane

358396:CHINAEXTREME RS10115
gene id: 358396:CHINAEXTREME_RS10115
uniprot id: M0L3H9
names: Caution
names: Function
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Glucose 1-dehydrogenase subfamily.
messages: Catalyzes the NAD(P)(+)-dependent oxidation of D-glucose to D-gluconate via gluconolactone. Can utilize both NAD(+) and NADP(+) as electron acceptor. Is involved in the degradation of glucose through a modified Entner-Doudoroff pathway.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

358396:CHINAEXTREME RS12675
gene id: 358396:CHINAEXTREME_RS12675
uniprot id: M0LFS8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TOP6B family.
messages: Homodimer. Heterotetramer of two Top6A and two Top6B chains.
messages: Relaxes both positive and negative superturns and exhibits a strong decatenase activity.

358396:CHINAEXTREME RS16185
gene id: 358396:CHINAEXTREME_RS16185
uniprot id: M0LB40
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic/archaeal RNase P protein component 2 family.
messages: Consists of a catalytic RNA component and at least 4-5 protein subunits.
messages: Cytoplasm
messages: Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.

358396:CHINAEXTREME RS04020
gene id: 358396:CHINAEXTREME_RS04020
uniprot id: M0LMB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

358396:CHINAEXTREME RS05320
gene id: 358396:CHINAEXTREME_RS05320
uniprot id: M0LKL1
names: Function
names: Similarity
messages: Belongs to the eIF-1A family.
messages: Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.

358396:CHINAEXTREME RS03920
gene id: 358396:CHINAEXTREME_RS03920
uniprot id: M0LM90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm

358396:CHINAEXTREME RS14700
gene id: 358396:CHINAEXTREME_RS14700
uniprot id: M0L2D3
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS17 family.

358396:CHINAEXTREME RS05595
gene id: 358396:CHINAEXTREME_RS05595
uniprot id: M0LMU8
names: Similarity
messages: Belongs to the IMPACT family.

358396:CHINAEXTREME RS16085
gene id: 358396:CHINAEXTREME_RS16085
uniprot id: M0LCB0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the methylaspartate mutase GlmE subunit family.
messages: Catalyzes the carbon skeleton rearrangement of L-glutamate to L-threo-3-methylaspartate ((2S,3S)-3-methylaspartate).
messages: Heterotetramer composed of 2 epsilon subunits (GlmE) and 2 sigma subunits (GlmS). GlmE exists as a homodimer and GlmS as a monomer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

358396:CHINAEXTREME RS12745
gene id: 358396:CHINAEXTREME_RS12745
uniprot id: M0LFY5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the beta-RFA-P synthase family.
messages: Catalyzes the condensation of 4-aminobenzoate (pABA) with 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to produce beta-ribofuranosylaminobenzene 5'-phosphate (beta-RFA-P).
messages: Homodimer.

358396:CHINAEXTREME RS14985
gene id: 358396:CHINAEXTREME_RS14985
uniprot id: M0LAM6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm

358396:CHINAEXTREME RS20735
gene id: 358396:CHINAEXTREME_RS20735
uniprot id: M0L9B9
names: Similarity
messages: Belongs to the CRISPR-associated protein Cas6/Cse3/CasE family.

358396:CHINAEXTREME RS00680
gene id: 358396:CHINAEXTREME_RS00680
uniprot id: M0LE57
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Although this enzyme belongs to the family of MTA phosphorylases based on sequence homology, it lacks several conserved amino acids in the substrate binding pocket that confer specificity towards MTA.
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Homohexamer. Dimer of a homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Purine nucleoside phosphorylase involved in purine salvage.

358396:CHINAEXTREME RS09565
gene id: 358396:CHINAEXTREME_RS09565
uniprot id: M0L7Y3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

358396:CHINAEXTREME RS16730
gene id: 358396:CHINAEXTREME_RS16730
uniprot id: M0LBF4
names: Subcellular Location Annotation
messages: Membrane

358396:CHINAEXTREME RS17515
gene id: 358396:CHINAEXTREME_RS17515
uniprot id: M0LHV5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the prefoldin subunit beta family.
messages: Cytoplasm
messages: Heterohexamer of two alpha and four beta subunits.
messages: Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding.

358396:CHINAEXTREME RS01810
gene id: 358396:CHINAEXTREME_RS01810
uniprot id: M0LEW7
names: Similarity
messages: Belongs to the thymidylate kinase family.

358396:CHINAEXTREME RS02985
gene id: 358396:CHINAEXTREME_RS02985
uniprot id: M0LNJ9
names: Similarity
messages: Belongs to the HerA family.

358396:CHINAEXTREME RS04260
gene id: 358396:CHINAEXTREME_RS04260
uniprot id: A0A1P8LML8
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

358396:CHINAEXTREME RS12720
gene id: 358396:CHINAEXTREME_RS12720
uniprot id: M0LFX9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis.

358396:CHINAEXTREME RS04830
gene id: 358396:CHINAEXTREME_RS04830
uniprot id: M0LN01
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

358396:CHINAEXTREME RS02750
gene id: 358396:CHINAEXTREME_RS02750
uniprot id: M0LRI0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

358396:CHINAEXTREME RS14825
gene id: 358396:CHINAEXTREME_RS14825
uniprot id: M0LAB9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

358396:CHINAEXTREME RS03445
gene id: 358396:CHINAEXTREME_RS03445
uniprot id: A0A1P8LW38
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

358396:CHINAEXTREME RS01130
gene id: 358396:CHINAEXTREME_RS01130
uniprot id: M0LDW2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

358396:CHINAEXTREME RS10820
gene id: 358396:CHINAEXTREME_RS10820
uniprot id: M0L713
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

358396:CHINAEXTREME RS06250
gene id: 358396:CHINAEXTREME_RS06250
uniprot id: M0M1N1
names: Function
names: Subunit
messages: Interacts with chemotaxis (Che) proteins as well as flagella accessory (Fla) proteins.
messages: Involved in taxis signal transduction.

358396:CHINAEXTREME RS06770
gene id: 358396:CHINAEXTREME_RS06770
uniprot id: M0LVE4
names: Subcellular Location Annotation
messages: Membrane

358396:CHINAEXTREME RS04565
gene id: 358396:CHINAEXTREME_RS04565
uniprot id: M0LPM1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

358396:CHINAEXTREME RS15620
gene id: 358396:CHINAEXTREME_RS15620
uniprot id: M0LCE1
names: Subcellular Location Annotation
messages: Membrane

358396:CHINAEXTREME RS20745
gene id: 358396:CHINAEXTREME_RS20745
uniprot id: M0LDN2
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

358396:CHINAEXTREME RS03175
gene id: 358396:CHINAEXTREME_RS03175
uniprot id: M0LRP9
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

358396:CHINAEXTREME RS19890
gene id: 358396:CHINAEXTREME_RS19890
uniprot id: M0LQZ5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

358396:CHINAEXTREME RS10740
gene id: 358396:CHINAEXTREME_RS10740
uniprot id: M0L534
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

358396:CHINAEXTREME RS05530
gene id: 358396:CHINAEXTREME_RS05530
uniprot id: M0LJR7
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

358396:CHINAEXTREME RS03735
gene id: 358396:CHINAEXTREME_RS03735
uniprot id: M0LQB8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Forms a complex with TatA.
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.

358396:CHINAEXTREME RS01325
gene id: 358396:CHINAEXTREME_RS01325
uniprot id: M0LDU4
names: Similarity
messages: Belongs to the anthranilate synthase component I family.

358396:CHINAEXTREME RS19630
gene id: 358396:CHINAEXTREME_RS19630
uniprot id: M0LUB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

358396:CHINAEXTREME RS15485
gene id: 358396:CHINAEXTREME_RS15485
uniprot id: M0LGU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAL/histidase family.
messages: Cytoplasm

358396:CHINAEXTREME RS18470
gene id: 358396:CHINAEXTREME_RS18470
uniprot id: M0LU10
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane
messages: Potential transporter for phosphate.

358396:CHINAEXTREME RS02295
gene id: 358396:CHINAEXTREME_RS02295
uniprot id: A0A1P8LLJ9
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: Part of the RNA polymerase complex.

358396:CHINAEXTREME RS19590
gene id: 358396:CHINAEXTREME_RS19590
uniprot id: M0LR64
names: Cofactor
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS27 family.
messages: Binds 1 zinc ion per subunit.

358396:CHINAEXTREME RS13965
gene id: 358396:CHINAEXTREME_RS13965
uniprot id: M0LFF8
names: Subunit
messages: Homodimer.

358396:CHINAEXTREME RS09165
gene id: 358396:CHINAEXTREME_RS09165
uniprot id: M0L997
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.

358396:CHINAEXTREME RS06905
gene id: 358396:CHINAEXTREME_RS06905
uniprot id: M0LU72
names: Similarity
messages: Belongs to the arylamine N-acetyltransferase family.

358396:CHINAEXTREME RS03950
gene id: 358396:CHINAEXTREME_RS03950
uniprot id: M0LNJ6
names: Similarity
messages: Belongs to the HMBS family.

358396:CHINAEXTREME RS17960
gene id: 358396:CHINAEXTREME_RS17960
uniprot id: M0LI45
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

358396:CHINAEXTREME RS15030
gene id: 358396:CHINAEXTREME_RS15030
uniprot id: M0LEM2
names: Similarity
messages: Belongs to the AOR/FOR family.

358396:CHINAEXTREME RS07965
gene id: 358396:CHINAEXTREME_RS07965
uniprot id: M0LWM5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

358396:CHINAEXTREME RS00610
gene id: 358396:CHINAEXTREME_RS00610
uniprot id: M0L1D5
names: Similarity
messages: Belongs to the peptidase S9C family.

358396:CHINAEXTREME RS10445
gene id: 358396:CHINAEXTREME_RS10445
uniprot id: M0L3P5
names: Subcellular Location Annotation
messages: Membrane

358396:CHINAEXTREME RS06565
gene id: 358396:CHINAEXTREME_RS06565
uniprot id: M0LXD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Membrane

358396:CHINAEXTREME RS03815
gene id: 358396:CHINAEXTREME_RS03815
uniprot id: M0LRI2
names: Similarity
messages: Belongs to the peptidase S8 family.

358396:CHINAEXTREME RS00905
gene id: 358396:CHINAEXTREME_RS00905
uniprot id: M0LE39
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methyltransferase superfamily. TrmY family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically catalyzes the N1-methylation of pseudouridine at position 54 (Psi54) in tRNAs.

358396:CHINAEXTREME RS02155
gene id: 358396:CHINAEXTREME_RS02155
uniprot id: M0LI31
names: Function
messages: Part of a potassium transport system.

358396:CHINAEXTREME RS19585
gene id: 358396:CHINAEXTREME_RS19585
uniprot id: A0A1P8LVM8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eIF-2-alpha family.
messages: Heterotrimer composed of an alpha, a beta and a gamma chain.
messages: eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA.

358396:CHINAEXTREME RS01150
gene id: 358396:CHINAEXTREME_RS01150
uniprot id: M0LF94
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

358396:CHINAEXTREME RS01675
gene id: 358396:CHINAEXTREME_RS01675
uniprot id: M0LIB3
names: Subcellular Location Annotation
messages: Membrane

358396:CHINAEXTREME RS03305
gene id: 358396:CHINAEXTREME_RS03305
uniprot id: M0LS48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

358396:CHINAEXTREME RS10990
gene id: 358396:CHINAEXTREME_RS10990
uniprot id: M0L2T5
names: Cofactor
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

358396:CHINAEXTREME RS20705
gene id: 358396:CHINAEXTREME_RS20705
uniprot id: M0LDY2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

358396:CHINAEXTREME RS16470
gene id: 358396:CHINAEXTREME_RS16470
uniprot id: M0LFS0
names: Similarity
messages: Belongs to the helicase family. RAD25/XPB subfamily.

358396:CHINAEXTREME RS01475
gene id: 358396:CHINAEXTREME_RS01475
uniprot id: M0LJM0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the archaeosine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs.

358396:CHINAEXTREME RS10800
gene id: 358396:CHINAEXTREME_RS10800
uniprot id: M0L8I2
names: Function
names: Similarity
messages: Belongs to the TFIIB family.
messages: Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB).

358396:CHINAEXTREME RS06475
gene id: 358396:CHINAEXTREME_RS06475
uniprot id: M0M0V4
names: Subcellular Location Annotation
messages: Endoplasmic reticulum
messages: Golgi apparatus
messages: Lysosome
messages: Secreted

358396:CHINAEXTREME RS12090
gene id: 358396:CHINAEXTREME_RS12090
uniprot id: M0LLC5
names: Similarity
messages: Belongs to the carbamate kinase family.

358396:CHINAEXTREME RS05150
gene id: 358396:CHINAEXTREME_RS05150
uniprot id: M0LLS1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: A structure-specific endonuclease that resolves Holliday junction (HJ) intermediates during genetic recombination. Cleaves 4-way DNA junctions introducing paired nicks in opposing strands, leaving a 5'-terminal phosphate and a 3'-terminal hydroxyl group that are ligated to produce recombinant products.
messages: Belongs to the Holliday junction resolvase Hjc family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.

358396:CHINAEXTREME RS09175
gene id: 358396:CHINAEXTREME_RS09175
uniprot id: M0L4K1
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

358396:CHINAEXTREME RS05700
gene id: 358396:CHINAEXTREME_RS05700
uniprot id: M0LP46
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

358396:CHINAEXTREME RS02505
gene id: 358396:CHINAEXTREME_RS02505
uniprot id: M0LJ39
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

358396:CHINAEXTREME RS17550
gene id: 358396:CHINAEXTREME_RS17550
uniprot id: M0LDE1
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

358396:CHINAEXTREME RS01920
gene id: 358396:CHINAEXTREME_RS01920
uniprot id: M0LJD5
names: Similarity
messages: Belongs to the PspA/IM30 family.

358396:CHINAEXTREME RS18295
gene id: 358396:CHINAEXTREME_RS18295
uniprot id: M0LQ67
names: Subcellular Location Annotation
messages: Cytoplasm

358396:CHINAEXTREME RS04760
gene id: 358396:CHINAEXTREME_RS04760
uniprot id: M0LPQ9
names: Similarity
messages: Belongs to the phosphohexose mutase family.

358396:CHINAEXTREME RS18370
gene id: 358396:CHINAEXTREME_RS18370
uniprot id: M0LQ52
names: Subcellular Location Annotation
messages: Membrane

358396:CHINAEXTREME RS06115
gene id: 358396:CHINAEXTREME_RS06115
uniprot id: M0M0H3
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

358396:CHINAEXTREME RS11820
gene id: 358396:CHINAEXTREME_RS11820
uniprot id: M0LDC6
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

358396:CHINAEXTREME RS20700
gene id: 358396:CHINAEXTREME_RS20700
uniprot id: M0LCL3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

358396:CHINAEXTREME RS12110
gene id: 358396:CHINAEXTREME_RS12110
uniprot id: M0LJL1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PyrI family.
messages: Binds 1 zinc ion per subunit.
messages: Contains catalytic and regulatory chains.
messages: Involved in allosteric regulation of aspartate carbamoyltransferase.

358396:CHINAEXTREME RS05260
gene id: 358396:CHINAEXTREME_RS05260
uniprot id: M0LNM2
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

358396:CHINAEXTREME RS16240
gene id: 358396:CHINAEXTREME_RS16240
uniprot id: M0LCE5
names: Subcellular Location Annotation
messages: Membrane

358396:CHINAEXTREME RS11855
gene id: 358396:CHINAEXTREME_RS11855
uniprot id: M0LC29
names: Similarity
messages: Belongs to the peptidase S8 family.

358396:CHINAEXTREME RS15400
gene id: 358396:CHINAEXTREME_RS15400
uniprot id: M0LDJ6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

358396:CHINAEXTREME RS15285
gene id: 358396:CHINAEXTREME_RS15285
uniprot id: M0LCM2
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

358396:CHINAEXTREME RS19625
gene id: 358396:CHINAEXTREME_RS19625
uniprot id: M0LV69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

358396:CHINAEXTREME RS06560
gene id: 358396:CHINAEXTREME_RS06560
uniprot id: M0LYJ0
names: Subcellular Location Annotation
messages: Membrane

358396:CHINAEXTREME RS03145
gene id: 358396:CHINAEXTREME_RS03145
uniprot id: A0A1P8LW36
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

358396:CHINAEXTREME RS15135
gene id: 358396:CHINAEXTREME_RS15135
uniprot id: M0LCJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane

358396:CHINAEXTREME RS09745
gene id: 358396:CHINAEXTREME_RS09745
uniprot id: M0L9K6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GGGP/HepGP synthase family. Group I subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids.

358396:CHINAEXTREME RS10585
gene id: 358396:CHINAEXTREME_RS10585
uniprot id: M0L6X6
names: Subcellular Location Annotation
messages: Cytoplasm

358396:CHINAEXTREME RS06935
gene id: 358396:CHINAEXTREME_RS06935
uniprot id: M0LUH5
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

358396:CHINAEXTREME RS19870
gene id: 358396:CHINAEXTREME_RS19870
uniprot id: M0LV13
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

358396:CHINAEXTREME RS02825
gene id: 358396:CHINAEXTREME_RS02825
uniprot id: M0LNH6
names: Similarity
messages: Belongs to the polysaccharide synthase family.

358396:CHINAEXTREME RS03420
gene id: 358396:CHINAEXTREME_RS03420
uniprot id: M0LMX9
names: Similarity
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.

358396:CHINAEXTREME RS10890
gene id: 358396:CHINAEXTREME_RS10890
uniprot id: M0L2R5
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

358396:CHINAEXTREME RS02140
gene id: 358396:CHINAEXTREME_RS02140
uniprot id: M0LER1
names: Function
names: Similarity
messages: Belongs to the KptA/TPT1 family.
messages: Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP-ribose 1''-2''-cyclic phosphate (APPR>P). May function as an ADP-ribosylase.

358396:CHINAEXTREME RS07390
gene id: 358396:CHINAEXTREME_RS07390
uniprot id: M0LXG1
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

358396:CHINAEXTREME RS06060
gene id: 358396:CHINAEXTREME_RS06060
uniprot id: M0LWP2
names: Similarity
messages: Belongs to the AAA ATPase family.

358396:CHINAEXTREME RS14960
gene id: 358396:CHINAEXTREME_RS14960
uniprot id: M0LAM9
names: Subcellular Location Annotation
messages: Membrane

358396:CHINAEXTREME RS17655
gene id: 358396:CHINAEXTREME_RS17655
uniprot id: M0LHY1
names: Similarity
names: Subunit
messages: Belongs to the HTP reductase family.
messages: Homodimer.

358396:CHINAEXTREME RS17775
gene id: 358396:CHINAEXTREME_RS17775
uniprot id: M0LI05
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

358396:CHINAEXTREME RS12425
gene id: 358396:CHINAEXTREME_RS12425
uniprot id: A0A1P8LRX0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

358396:CHINAEXTREME RS05560
gene id: 358396:CHINAEXTREME_RS05560
uniprot id: A0A1P8LNA2
names: Subcellular Location Annotation
messages: Membrane

358396:CHINAEXTREME RS17650
gene id: 358396:CHINAEXTREME_RS17650
uniprot id: M0LGR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uridine kinase family.
messages: Cytoplasm

358396:CHINAEXTREME RS04190
gene id: 358396:CHINAEXTREME_RS04190
uniprot id: M0LMK5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M20A family. LysK subfamily.
messages: Binds 2 Zn(2+) or Co(2+) ions per subunit.
messages: Catalyzes the release of L-lysine from [LysW]-gamma-L-lysine and the release of L-ornithine from [LysW]-L-ornithine.
messages: Cytoplasm

358396:CHINAEXTREME RS02875
gene id: 358396:CHINAEXTREME_RS02875
uniprot id: M0LSJ0
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.

358396:CHINAEXTREME RS13840
gene id: 358396:CHINAEXTREME_RS13840
uniprot id: M0LGS8
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL32 family.

358396:CHINAEXTREME RS11290
gene id: 358396:CHINAEXTREME_RS11290
uniprot id: M0L673
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GHMP kinase family. Mevalonate kinase subfamily.
messages: Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)-mevalonate 5-phosphate (MVAP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids.
messages: Cytoplasm
messages: Homodimer.

358396:CHINAEXTREME RS08275
gene id: 358396:CHINAEXTREME_RS08275
uniprot id: M0LYR1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eIF-5A family.
messages: Cytoplasm
messages: Functions by promoting the formation of the first peptide bond.

358396:CHINAEXTREME RS10995
gene id: 358396:CHINAEXTREME_RS10995
uniprot id: M0L478
names: Similarity
messages: Belongs to the hemerythrin family.

358396:CHINAEXTREME RS04975
gene id: 358396:CHINAEXTREME_RS04975
uniprot id: M0LLN8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).

358396:CHINAEXTREME RS14805
gene id: 358396:CHINAEXTREME_RS14805
uniprot id: M0LEX4
names: Similarity
messages: Belongs to the transcriptional regulator TrmB family.

358396:CHINAEXTREME RS05275
gene id: 358396:CHINAEXTREME_RS05275
uniprot id: M0LKB6
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

358396:CHINAEXTREME RS05690
gene id: 358396:CHINAEXTREME_RS05690
uniprot id: M0LL50
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

358396:CHINAEXTREME RS08600
gene id: 358396:CHINAEXTREME_RS08600
uniprot id: M0LYI8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

358396:CHINAEXTREME RS17985
gene id: 358396:CHINAEXTREME_RS17985
uniprot id: M0LI50
names: Subcellular Location Annotation
messages: Membrane

358396:CHINAEXTREME RS00750
gene id: 358396:CHINAEXTREME_RS00750
uniprot id: M0LFH8
names: Subcellular Location Annotation
messages: Membrane

358396:CHINAEXTREME RS08170
gene id: 358396:CHINAEXTREME_RS08170
uniprot id: M0LVB5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

358396:CHINAEXTREME RS08255
gene id: 358396:CHINAEXTREME_RS08255
uniprot id: M0LWF7
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

358396:CHINAEXTREME RS10075
gene id: 358396:CHINAEXTREME_RS10075
uniprot id: M0L4R7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

358396:CHINAEXTREME RS07710
gene id: 358396:CHINAEXTREME_RS07710
uniprot id: M0LXX1
names: Similarity
messages: Belongs to the SCO1/2 family.

358396:CHINAEXTREME RS07665
gene id: 358396:CHINAEXTREME_RS07665
uniprot id: M0LX87
names: Subcellular Location Annotation
messages: Membrane

358396:CHINAEXTREME RS13845
gene id: 358396:CHINAEXTREME_RS13845
uniprot id: M0LIN4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

358396:CHINAEXTREME RS09405
gene id: 358396:CHINAEXTREME_RS09405
uniprot id: M0L4P3
names: Caution
names: Similarity
messages: Belongs to the peptidase S8 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

358396:CHINAEXTREME RS16280
gene id: 358396:CHINAEXTREME_RS16280
uniprot id: M0LB58
names: Similarity
messages: Belongs to the GARS family.

358396:CHINAEXTREME RS19320
gene id: 358396:CHINAEXTREME_RS19320
uniprot id: M0LSD8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

358396:CHINAEXTREME RS04065
gene id: 358396:CHINAEXTREME_RS04065
uniprot id: A0A1P8LW37
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

358396:CHINAEXTREME RS05280
gene id: 358396:CHINAEXTREME_RS05280
uniprot id: M0LLT8
names: Similarity
messages: Belongs to the activator 1 small subunits family. RfcS subfamily.

358396:CHINAEXTREME RS10090
gene id: 358396:CHINAEXTREME_RS10090
uniprot id: M0L3H5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

358396:CHINAEXTREME RS18180
gene id: 358396:CHINAEXTREME_RS18180
uniprot id: M0LPZ0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

358396:CHINAEXTREME RS04025
gene id: 358396:CHINAEXTREME_RS04025
uniprot id: M0LNL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

358396:CHINAEXTREME RS06945
gene id: 358396:CHINAEXTREME_RS06945
uniprot id: M0LXN5
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

358396:CHINAEXTREME RS18240
gene id: 358396:CHINAEXTREME_RS18240
uniprot id: M0LU51
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

358396:CHINAEXTREME RS05570
gene id: 358396:CHINAEXTREME_RS05570
uniprot id: A0A1P8LW16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

358396:CHINAEXTREME RS16110
gene id: 358396:CHINAEXTREME_RS16110
uniprot id: M0LCB8
names: Function
names: Similarity
messages: Belongs to the archaeal-type GTP cyclohydrolase family.
messages: Catalyzes the formation of 2-amino-5-formylamino-6-ribofuranosylamino-4(3H)-pyrimidinone ribonucleotide monophosphate and inorganic phosphate from GTP. Also has an independent pyrophosphate phosphohydrolase activity.

358396:CHINAEXTREME RS19830
gene id: 358396:CHINAEXTREME_RS19830
uniprot id: M0LS49
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal Rpo12/eukaryotic RPC10 RNA polymerase subunit family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

358396:CHINAEXTREME RS11380
gene id: 358396:CHINAEXTREME_RS11380
uniprot id: M0L343
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL24 family.
messages: Binds to the 23S rRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L14.

358396:CHINAEXTREME RS13525
gene id: 358396:CHINAEXTREME_RS13525
uniprot id: M0LHQ4
names: Function
messages: Part of a potassium transport system.

358396:CHINAEXTREME RS11175
gene id: 358396:CHINAEXTREME_RS11175
uniprot id: M0L2X3
names: Subcellular Location Annotation
messages: Membrane

358396:CHINAEXTREME RS05040
gene id: 358396:CHINAEXTREME_RS05040
uniprot id: M0LKF8
names: Function
names: Similarity
messages: Belongs to the eIF-6 family.
messages: Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex.

358396:CHINAEXTREME RS04595
gene id: 358396:CHINAEXTREME_RS04595
uniprot id: M0LQU6
names: Function
names: Similarity
messages: Belongs to the CDC6/cdc18 family.
messages: Involved in regulation of DNA replication.

358396:CHINAEXTREME RS01275
gene id: 358396:CHINAEXTREME_RS01275
uniprot id: M0LDV6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

358396:CHINAEXTREME RS11190
gene id: 358396:CHINAEXTREME_RS11190
uniprot id: M0L7J1
names: Function
names: Similarity
messages: Belongs to the CDC6/cdc18 family.
messages: Involved in regulation of DNA replication.

358396:CHINAEXTREME RS08800
gene id: 358396:CHINAEXTREME_RS08800
uniprot id: M0L6B6
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

358396:CHINAEXTREME RS04145
gene id: 358396:CHINAEXTREME_RS04145
uniprot id: M0LMD8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

358396:CHINAEXTREME RS16090
gene id: 358396:CHINAEXTREME_RS16090
uniprot id: A0A1P8LTT0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the methylamine corrinoid protein family.
messages: Belongs to the methylaspartate mutase GlmS subunit family.
messages: Catalyzes the carbon skeleton rearrangement of L-glutamate to L-threo-3-methylaspartate ((2S,3S)-3-methylaspartate).
messages: Heterotetramer composed of 2 epsilon subunits (GlmE) and 2 sigma subunits (GlmS). GlmE exists as a homodimer and GlmS as a monomer.

358396:CHINAEXTREME RS16640
gene id: 358396:CHINAEXTREME_RS16640
uniprot id: M0LFV3
names: Similarity
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.

358396:CHINAEXTREME RS05045
gene id: 358396:CHINAEXTREME_RS05045
uniprot id: M0LK83
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL31 family.
messages: Belongs to the ribosomal protein L31e family.

358396:CHINAEXTREME RS07195
gene id: 358396:CHINAEXTREME_RS07195
uniprot id: M0LV76
names: Similarity
messages: Belongs to the PDCD5 family.

358396:CHINAEXTREME RS13425
gene id: 358396:CHINAEXTREME_RS13425
uniprot id: M0LHN4
names: Function
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.

358396:CHINAEXTREME RS16675
gene id: 358396:CHINAEXTREME_RS16675
uniprot id: M0LBE3
names: Subcellular Location Annotation
messages: Membrane

358396:CHINAEXTREME RS00390
gene id: 358396:CHINAEXTREME_RS00390
uniprot id: M0L2U6
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

358396:CHINAEXTREME RS07880
gene id: 358396:CHINAEXTREME_RS07880
uniprot id: M0LVG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

358396:CHINAEXTREME RS07565
gene id: 358396:CHINAEXTREME_RS07565
uniprot id: M0LXB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TspO/BZRP family.
messages: Membrane

358396:CHINAEXTREME RS13510
gene id: 358396:CHINAEXTREME_RS13510
uniprot id: M0LKS5
names: Similarity
messages: Belongs to the BtpA family.

358396:CHINAEXTREME RS08710
gene id: 358396:CHINAEXTREME_RS08710
uniprot id: M0L9H7
names: Caution
names: Function
names: Similarity
messages: Belongs to the eIF-1A family.
messages: Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

358396:CHINAEXTREME RS07650
gene id: 358396:CHINAEXTREME_RS07650
uniprot id: M0LTR8
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

358396:CHINAEXTREME RS16215
gene id: 358396:CHINAEXTREME_RS16215
uniprot id: M0LCD9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.

358396:CHINAEXTREME RS04335
gene id: 358396:CHINAEXTREME_RS04335
uniprot id: M0LQN9
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

358396:CHINAEXTREME RS03155
gene id: 358396:CHINAEXTREME_RS03155
uniprot id: M0LPR6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
messages: Homodimer.

358396:CHINAEXTREME RS02800
gene id: 358396:CHINAEXTREME_RS02800
uniprot id: M0LNB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal histone HMF family.
messages: Chromosome
messages: Cytoplasm

358396:CHINAEXTREME RS18215
gene id: 358396:CHINAEXTREME_RS18215
uniprot id: M0LU57
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

358396:CHINAEXTREME RS01400
gene id: 358396:CHINAEXTREME_RS01400
uniprot id: M0LDS5
names: Function
names: Similarity
messages: Belongs to the TFIIB family.
messages: Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB).

358396:CHINAEXTREME RS07495
gene id: 358396:CHINAEXTREME_RS07495
uniprot id: M0LTV1
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

358396:CHINAEXTREME RS21160
gene id: 358396:CHINAEXTREME_RS21160
uniprot id: M0LA39
names: Function
names: Similarity
messages: Belongs to the CDC6/cdc18 family.
messages: Involved in regulation of DNA replication.

358396:CHINAEXTREME RS18590
gene id: 358396:CHINAEXTREME_RS18590
uniprot id: M0LTZ0
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

358396:CHINAEXTREME RS10305
gene id: 358396:CHINAEXTREME_RS10305
uniprot id: M0L4V4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

358396:CHINAEXTREME RS10685
gene id: 358396:CHINAEXTREME_RS10685
uniprot id: M0L524
names: Function
names: Similarity
names: Subunit
messages: Belongs to the activator 1 small subunits family. RfcL subfamily.
messages: Heteromultimer composed of small subunits (RfcS) and large subunits (RfcL).
messages: Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA.

358396:CHINAEXTREME RS13810
gene id: 358396:CHINAEXTREME_RS13810
uniprot id: M0LFC4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of alpha (SecY), beta (SecG) and gamma (SecE) subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. May interact with SecDF, and other proteins may be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

358396:CHINAEXTREME RS14105
gene id: 358396:CHINAEXTREME_RS14105
uniprot id: M0LIT1
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

358396:CHINAEXTREME RS01555
gene id: 358396:CHINAEXTREME_RS01555
uniprot id: M0LID4
names: Similarity
messages: Belongs to the AOR/FOR family.

358396:CHINAEXTREME RS14585
gene id: 358396:CHINAEXTREME_RS14585
uniprot id: M0L5L3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

358396:CHINAEXTREME RS02315
gene id: 358396:CHINAEXTREME_RS02315
uniprot id: M0LI03
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Participates in transcription termination.

358396:CHINAEXTREME RS03495
gene id: 358396:CHINAEXTREME_RS03495
uniprot id: M0LM04
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

358396:CHINAEXTREME RS11630
gene id: 358396:CHINAEXTREME_RS11630
uniprot id: A0A1P8LRG9
names: Subcellular Location Annotation
messages: Membrane

358396:CHINAEXTREME RS18350
gene id: 358396:CHINAEXTREME_RS18350
uniprot id: M0LU33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Cytoplasm

358396:CHINAEXTREME RS09525
gene id: 358396:CHINAEXTREME_RS09525
uniprot id: A0A1P8LWC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

358396:CHINAEXTREME RS06950
gene id: 358396:CHINAEXTREME_RS06950
uniprot id: M0LVB0
names: Similarity
messages: Belongs to the eIF-2B alpha/beta/delta subunits family.

358396:CHINAEXTREME RS10415
gene id: 358396:CHINAEXTREME_RS10415
uniprot id: M0L8A8
names: Similarity
messages: Belongs to the NAPRTase family.

358396:CHINAEXTREME RS08180
gene id: 358396:CHINAEXTREME_RS08180
uniprot id: M0LZH8
names: Similarity
messages: Belongs to the proline racemase family.

358396:CHINAEXTREME RS14930
gene id: 358396:CHINAEXTREME_RS14930
uniprot id: M0LCN5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

358396:CHINAEXTREME RS15380
gene id: 358396:CHINAEXTREME_RS15380
uniprot id: M0LFI5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

358396:CHINAEXTREME RS00230
gene id: 358396:CHINAEXTREME_RS00230
uniprot id: M0LSC9
names: Similarity
messages: In the C-terminal section; belongs to the complex I 49 kDa subunit family.

358396:CHINAEXTREME RS02590
gene id: 358396:CHINAEXTREME_RS02590
uniprot id: M0LEH7
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

358396:CHINAEXTREME RS20190
gene id: 358396:CHINAEXTREME_RS20190
uniprot id: M0LRY5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

358396:CHINAEXTREME RS08360
gene id: 358396:CHINAEXTREME_RS08360
uniprot id: M0LV60
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

358396:CHINAEXTREME RS13260
gene id: 358396:CHINAEXTREME_RS13260
uniprot id: M0LKN3
names: Similarity
messages: Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.

358396:CHINAEXTREME RS08790
gene id: 358396:CHINAEXTREME_RS08790
uniprot id: M0LB14
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

358396:CHINAEXTREME RS00545
gene id: 358396:CHINAEXTREME_RS00545
uniprot id: M0L5W8
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

358396:CHINAEXTREME RS06290
gene id: 358396:CHINAEXTREME_RS06290
uniprot id: M0LXI3
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS6 family.

358396:CHINAEXTREME RS08685
gene id: 358396:CHINAEXTREME_RS08685
uniprot id: M0L9H0
names: Subcellular Location Annotation
messages: Cell membrane

358396:CHINAEXTREME RS01180
gene id: 358396:CHINAEXTREME_RS01180
uniprot id: M0LDY0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAC-alpha family.
messages: Contacts the emerging nascent chain on the ribosome.
messages: Homodimer. Interacts with the ribosome. Binds ribosomal RNA.

358396:CHINAEXTREME RS15765
gene id: 358396:CHINAEXTREME_RS15765
uniprot id: M0LBJ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the methyltransferase superfamily. Fibrillarin family.
messages: Interacts with nop5. Component of box C/D small ribonucleoprotein (sRNP) particles that contain rpl7ae, FlpA and nop5, plus a guide RNA.
messages: Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA.

358396:CHINAEXTREME RS05010
gene id: 358396:CHINAEXTREME_RS05010
uniprot id: M0LPQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

358396:CHINAEXTREME RS16285
gene id: 358396:CHINAEXTREME_RS16285
uniprot id: M0LCF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Nucleus

358396:CHINAEXTREME RS01005
gene id: 358396:CHINAEXTREME_RS01005
uniprot id: M0LE20
names: Function
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2.

358396:CHINAEXTREME RS09360
gene id: 358396:CHINAEXTREME_RS09360
uniprot id: M0L7U8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

358396:CHINAEXTREME RS07540
gene id: 358396:CHINAEXTREME_RS07540
uniprot id: M0LXB8
names: Similarity
messages: Belongs to the citrate synthase family.

358396:CHINAEXTREME RS00850
gene id: 358396:CHINAEXTREME_RS00850
uniprot id: M0LFF7
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

358396:CHINAEXTREME RS20030
gene id: 358396:CHINAEXTREME_RS20030
uniprot id: M0LU14
names: Subcellular Location Annotation
messages: Endoplasmic reticulum
messages: Golgi apparatus
messages: Lysosome
messages: Secreted

358396:CHINAEXTREME RS01680
gene id: 358396:CHINAEXTREME_RS01680
uniprot id: M0LGE7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

358396:CHINAEXTREME RS11715
gene id: 358396:CHINAEXTREME_RS11715
uniprot id: A0A1P8LRK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

358396:CHINAEXTREME RS13650
gene id: 358396:CHINAEXTREME_RS13650
uniprot id: M0LJS0
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

358396:CHINAEXTREME RS02070
gene id: 358396:CHINAEXTREME_RS02070
uniprot id: M0LEW2
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

358396:CHINAEXTREME RS15230
gene id: 358396:CHINAEXTREME_RS15230
uniprot id: M0LCJ4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: S-layer

358396:CHINAEXTREME RS17680
gene id: 358396:CHINAEXTREME_RS17680
uniprot id: M0LHY7
names: Subcellular Location Annotation
messages: Cytoplasm

358396:CHINAEXTREME RS02840
gene id: 358396:CHINAEXTREME_RS02840
uniprot id: M0LRJ5
names: Similarity
messages: Belongs to the MoaB/Mog family.

358396:CHINAEXTREME RS04195
gene id: 358396:CHINAEXTREME_RS04195
uniprot id: M0LME9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. LysJ subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in both the arginine and lysine biosynthetic pathways.

358396:CHINAEXTREME RS04700
gene id: 358396:CHINAEXTREME_RS04700
uniprot id: M0LLJ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
messages: Homodimer.

358396:CHINAEXTREME RS14145
gene id: 358396:CHINAEXTREME_RS14145
uniprot id: M0LFJ3
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

358396:CHINAEXTREME RS12610
gene id: 358396:CHINAEXTREME_RS12610
uniprot id: A0A1P8LRY8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

358396:CHINAEXTREME RS17570
gene id: 358396:CHINAEXTREME_RS17570
uniprot id: M0LDE5
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MRE11/RAD32 family.
messages: Binds 2 manganese ions per subunit.
messages: Homodimer. Forms a heterotetramer composed of two Mre11 subunits and two Rad50 subunits.
messages: Nuclease activity is regulated by Rad50.
messages: Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. Mre11 binds to DSB ends and has both double-stranded 3'-5' exonuclease activity and single-stranded endonuclease activity.

358396:CHINAEXTREME RS18550
gene id: 358396:CHINAEXTREME_RS18550
uniprot id: M0LT56
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family.

358396:CHINAEXTREME RS01190
gene id: 358396:CHINAEXTREME_RS01190
uniprot id: M0LID9
names: Similarity
messages: Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.

358396:CHINAEXTREME RS13905
gene id: 358396:CHINAEXTREME_RS13905
uniprot id: M0LFH6
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

358396:CHINAEXTREME RS11800
gene id: 358396:CHINAEXTREME_RS11800
uniprot id: M0LFB0
names: Similarity
messages: Belongs to the DNA polymerase type-B family.

358396:CHINAEXTREME RS19185
gene id: 358396:CHINAEXTREME_RS19185
uniprot id: M0LVF1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

358396:CHINAEXTREME RS18545
gene id: 358396:CHINAEXTREME_RS18545
uniprot id: M0LTZ7
names: Subcellular Location Annotation
messages: Membrane

358396:CHINAEXTREME RS02450
gene id: 358396:CHINAEXTREME_RS02450
uniprot id: M0LEP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC41A transporter family.
messages: Membrane

358396:CHINAEXTREME RS05015
gene id: 358396:CHINAEXTREME_RS05015
uniprot id: M0LKF4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the prefoldin alpha subunit family.
messages: Belongs to the prefoldin subunit alpha family.
messages: Cytoplasm
messages: Heterohexamer of two alpha and four beta subunits.
messages: Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding.

358396:CHINAEXTREME RS15520
gene id: 358396:CHINAEXTREME_RS15520
uniprot id: M0LCC0
names: Function
names: Similarity
messages: Belongs to the AdoMet synthase 2 family.
messages: Catalyzes the formation of S-adenosylmethionine from methionine and ATP.

358396:CHINAEXTREME RS08895
gene id: 358396:CHINAEXTREME_RS08895
uniprot id: M0L9L1
names: Function
names: Similarity
messages: Belongs to the LeuD family. LeuD type 2 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.

358396:CHINAEXTREME RS02495
gene id: 358396:CHINAEXTREME_RS02495
uniprot id: M0LEK6
names: Subcellular Location Annotation
messages: Membrane

358396:CHINAEXTREME RS00965
gene id: 358396:CHINAEXTREME_RS00965
uniprot id: M0LII3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Involved in protein export.
messages: Membrane
messages: Part of the protein translocation apparatus. Forms a complex with SecD.

358396:CHINAEXTREME RS07780
gene id: 358396:CHINAEXTREME_RS07780
uniprot id: M0LTP6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C15 family.
messages: Cytoplasm
messages: Removes 5-oxoproline from various penultimate amino acid residues except L-proline.

358396:CHINAEXTREME RS07735
gene id: 358396:CHINAEXTREME_RS07735
uniprot id: A0A1P8LW77
names: Similarity
messages: Belongs to the HypE family.

358396:CHINAEXTREME RS16480
gene id: 358396:CHINAEXTREME_RS16480
uniprot id: M0LCJ8
names: Function
names: Similarity
messages: Belongs to the TFIIB family.
messages: Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB).

358396:CHINAEXTREME RS03390
gene id: 358396:CHINAEXTREME_RS03390
uniprot id: M0LN19
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

358396:CHINAEXTREME RS13105
gene id: 358396:CHINAEXTREME_RS13105
uniprot id: M0LJE9
names: Similarity
messages: Belongs to the TPP enzyme family.

358396:CHINAEXTREME RS01335
gene id: 358396:CHINAEXTREME_RS01335
uniprot id: M0LIB2
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

358396:CHINAEXTREME RS03590
gene id: 358396:CHINAEXTREME_RS03590
uniprot id: M0LM20
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

358396:CHINAEXTREME RS16270
gene id: 358396:CHINAEXTREME_RS16270
uniprot id: M0LFN5
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

358396:CHINAEXTREME RS19335
gene id: 358396:CHINAEXTREME_RS19335
uniprot id: M0LVC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

358396:CHINAEXTREME RS11395
gene id: 358396:CHINAEXTREME_RS11395
uniprot id: M0L696
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

358396:CHINAEXTREME RS10140
gene id: 358396:CHINAEXTREME_RS10140
uniprot id: M0L856
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY (alpha), SecG (beta) and SecE (gamma) subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. May interact with SecDF, and other proteins may be involved.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.
messages: Membrane

358396:CHINAEXTREME RS20380
gene id: 358396:CHINAEXTREME_RS20380
uniprot id: A0A1P8LWJ4
names: Caution
names: Function
names: Similarity
messages: Belongs to the CDC6/cdc18 family.
messages: Involved in regulation of DNA replication.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

358396:CHINAEXTREME RS00785
gene id: 358396:CHINAEXTREME_RS00785
uniprot id: M0LE34
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

358396:CHINAEXTREME RS01655
gene id: 358396:CHINAEXTREME_RS01655
uniprot id: M0LGF3
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

358396:CHINAEXTREME RS01245
gene id: 358396:CHINAEXTREME_RS01245
uniprot id: M0LF72
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

358396:CHINAEXTREME RS16985
gene id: 358396:CHINAEXTREME_RS16985
uniprot id: M0LQ09
names: Similarity
messages: Belongs to the glutaredoxin family.

358396:CHINAEXTREME RS06230
gene id: 358396:CHINAEXTREME_RS06230
uniprot id: M0M106
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Archaeal flagellum
messages: Belongs to the archaeal flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of archaeal flagella.

358396:CHINAEXTREME RS15280
gene id: 358396:CHINAEXTREME_RS15280
uniprot id: M0LCK5
names: Subcellular Location Annotation
messages: Membrane

358396:CHINAEXTREME RS06820
gene id: 358396:CHINAEXTREME_RS06820
uniprot id: M0LVD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsbB family. BdbC subfamily.
messages: Membrane

358396:CHINAEXTREME RS18480
gene id: 358396:CHINAEXTREME_RS18480
uniprot id: M0LR63
names: Subcellular Location Annotation
messages: Membrane

358396:CHINAEXTREME RS15145
gene id: 358396:CHINAEXTREME_RS15145
uniprot id: M0LDU8
names: Subcellular Location Annotation
messages: Membrane

358396:CHINAEXTREME RS07410
gene id: 358396:CHINAEXTREME_RS07410
uniprot id: M0LY43
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family.
messages: Dimethylates a single guanine residue at position 26 of a number of tRNAs using S-adenosyl-L-methionine as donor of the methyl groups.

358396:CHINAEXTREME RS15465
gene id: 358396:CHINAEXTREME_RS15465
uniprot id: A0A1P8LWD2
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.

358396:CHINAEXTREME RS18035
gene id: 358396:CHINAEXTREME_RS18035
uniprot id: M0LI58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Membrane

358396:CHINAEXTREME RS13860
gene id: 358396:CHINAEXTREME_RS13860
uniprot id: M0LFD5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; contacts the 5S rRNA and probably tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. May contact the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

358396:CHINAEXTREME RS19450
gene id: 358396:CHINAEXTREME_RS19450
uniprot id: A0A1P8LVH4
names: Subcellular Location Annotation
messages: Membrane

358396:CHINAEXTREME RS00945
gene id: 358396:CHINAEXTREME_RS00945
uniprot id: M0LHA3
names: Similarity
messages: Belongs to the peptidase S9C family.

358396:CHINAEXTREME RS05020
gene id: 358396:CHINAEXTREME_RS05020
uniprot id: M0LK77
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL20 family.
messages: Part of the 50S ribosomal subunit. Binds 23S rRNA.

358396:CHINAEXTREME RS04210
gene id: 358396:CHINAEXTREME_RS04210
uniprot id: A0A1P8LMK4
names: Similarity
messages: Belongs to the RimK family. LysX subfamily.

358396:CHINAEXTREME RS16170
gene id: 358396:CHINAEXTREME_RS16170
uniprot id: A0A1P8LWI8
names: Similarity
messages: Belongs to the FUN14 family.

358396:CHINAEXTREME RS04635
gene id: 358396:CHINAEXTREME_RS04635
uniprot id: M0LMW3
names: Similarity
messages: Belongs to the aspartokinase family.

358396:CHINAEXTREME RS15215
gene id: 358396:CHINAEXTREME_RS15215
uniprot id: M0LDW4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TPP enzyme family. MenD subfamily.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
messages: Homodimer.

358396:CHINAEXTREME RS04350
gene id: 358396:CHINAEXTREME_RS04350
uniprot id: M0LMI1
names: Similarity
messages: Belongs to the CGI121/TPRKB family.

358396:CHINAEXTREME RS18820
gene id: 358396:CHINAEXTREME_RS18820
uniprot id: M0LRA9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

358396:CHINAEXTREME RS00985
gene id: 358396:CHINAEXTREME_RS00985
uniprot id: M0LDZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

358396:CHINAEXTREME RS09230
gene id: 358396:CHINAEXTREME_RS09230
uniprot id: M0L5Z4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.

358396:CHINAEXTREME RS09030
gene id: 358396:CHINAEXTREME_RS09030
uniprot id: M0L9N4
names: Subcellular Location Annotation
messages: Membrane

358396:CHINAEXTREME RS11230
gene id: 358396:CHINAEXTREME_RS11230
uniprot id: M0L2Y3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

358396:CHINAEXTREME RS03385
gene id: 358396:CHINAEXTREME_RS03385
uniprot id: M0LS60
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

358396:CHINAEXTREME RS15495
gene id: 358396:CHINAEXTREME_RS15495
uniprot id: M0LCB6
names: Similarity
messages: Belongs to the arginase family.

358396:CHINAEXTREME RS10860
gene id: 358396:CHINAEXTREME_RS10860
uniprot id: M0L2Q9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

358396:CHINAEXTREME RS06555
gene id: 358396:CHINAEXTREME_RS06555
uniprot id: M0M0U0
names: Function
names: Similarity
messages: Belongs to the V-ATPase E subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

358396:CHINAEXTREME RS11185
gene id: 358396:CHINAEXTREME_RS11185
uniprot id: M0L651
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.
messages: Monomer.

358396:CHINAEXTREME RS01635
gene id: 358396:CHINAEXTREME_RS01635
uniprot id: M0LF00
names: Similarity
messages: Belongs to the SAICAR synthetase family.

358396:CHINAEXTREME RS11265
gene id: 358396:CHINAEXTREME_RS11265
uniprot id: M0L4C7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal Rpo10/eukaryotic RPB10 RNA polymerase subunit family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

358396:CHINAEXTREME RS15855
gene id: 358396:CHINAEXTREME_RS15855
uniprot id: M0LC63
names: Function
names: Similarity
messages: Belongs to the deoxyhypusine synthase family.
messages: Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue.

358396:CHINAEXTREME RS18440
gene id: 358396:CHINAEXTREME_RS18440
uniprot id: M0LQ38
names: Subcellular Location Annotation
messages: Membrane

358396:CHINAEXTREME RS15320
gene id: 358396:CHINAEXTREME_RS15320
uniprot id: A0A1P8LTE9
names: Similarity
messages: Belongs to the SCO1/2 family.

358396:CHINAEXTREME RS03500
gene id: 358396:CHINAEXTREME_RS03500
uniprot id: M0LNB4
names: Similarity
messages: Belongs to the SUI1 family.

358396:CHINAEXTREME RS02050
gene id: 358396:CHINAEXTREME_RS02050
uniprot id: A0A1P8LLF3
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

358396:CHINAEXTREME RS13225
gene id: 358396:CHINAEXTREME_RS13225
uniprot id: M0LHK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmC/CycZ/HelC family.
messages: Membrane

358396:CHINAEXTREME RS13820
gene id: 358396:CHINAEXTREME_RS13820
uniprot id: M0LIM9
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

358396:CHINAEXTREME RS00735
gene id: 358396:CHINAEXTREME_RS00735
uniprot id: M0LE47
names: Subcellular Location Annotation
messages: Membrane

358396:CHINAEXTREME RS07180
gene id: 358396:CHINAEXTREME_RS07180
uniprot id: M0LUD8
names: Subcellular Location Annotation
messages: Membrane

358396:CHINAEXTREME RS10025
gene id: 358396:CHINAEXTREME_RS10025
uniprot id: M0L6N2
names: Subcellular Location Annotation
messages: Membrane

358396:CHINAEXTREME RS07365
gene id: 358396:CHINAEXTREME_RS07365
uniprot id: M0LXG6
names: Similarity
messages: Belongs to the UPF0146 family.

358396:CHINAEXTREME RS14860
gene id: 358396:CHINAEXTREME_RS14860
uniprot id: M0LDL3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CetZ family.
messages: Cytoplasm
messages: Involved in cell shape control.

358396:CHINAEXTREME RS15020
gene id: 358396:CHINAEXTREME_RS15020
uniprot id: M0LA50
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

358396:CHINAEXTREME RS12475
gene id: 358396:CHINAEXTREME_RS12475
uniprot id: M0LKX5
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS8 family.
messages: Part of the 30S ribosomal subunit.

358396:CHINAEXTREME RS18700
gene id: 358396:CHINAEXTREME_RS18700
uniprot id: M0LR24
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the aTrm56 family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs.

358396:CHINAEXTREME RS10040
gene id: 358396:CHINAEXTREME_RS10040
uniprot id: M0L3D4
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

358396:CHINAEXTREME RS20005
gene id: 358396:CHINAEXTREME_RS20005
uniprot id: M0LU22
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

358396:CHINAEXTREME RS14235
gene id: 358396:CHINAEXTREME_RS14235
uniprot id: A0A1P8LWH1
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

358396:CHINAEXTREME RS12445
gene id: 358396:CHINAEXTREME_RS12445
uniprot id: A0A1P8LRX9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

358396:CHINAEXTREME RS15425
gene id: 358396:CHINAEXTREME_RS15425
uniprot id: M0LDK0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

358396:CHINAEXTREME RS03370
gene id: 358396:CHINAEXTREME_RS03370
uniprot id: M0LMW9
names: Caution
names: Function
names: Similarity
messages: Belongs to the ornithine cyclodeaminase/mu-crystallin family. Archaeal alanine dehydrogenase subfamily.
messages: Catalyzes the NAD(+)-dependent oxidative deamination of L-alanine to pyruvate, and the reverse reaction, the reductive amination of pyruvate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

358396:CHINAEXTREME RS01065
gene id: 358396:CHINAEXTREME_RS01065
uniprot id: M0LH81
names: Similarity
messages: Belongs to the IPP isomerase type 1 family.

358396:CHINAEXTREME RS13530
gene id: 358396:CHINAEXTREME_RS13530
uniprot id: M0LJM2
names: Subcellular Location Annotation
messages: Membrane

358396:CHINAEXTREME RS19940
gene id: 358396:CHINAEXTREME_RS19940
uniprot id: M0LQR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

358396:CHINAEXTREME RS08515
gene id: 358396:CHINAEXTREME_RS08515
uniprot id: M0LV31
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Cell membrane
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

358396:CHINAEXTREME RS11275
gene id: 358396:CHINAEXTREME_RS11275
uniprot id: M0L7L4
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

358396:CHINAEXTREME RS00210
gene id: 358396:CHINAEXTREME_RS00210
uniprot id: M0LSD4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

358396:CHINAEXTREME RS15775
gene id: 358396:CHINAEXTREME_RS15775
uniprot id: M0LCW0
names: Subcellular Location Annotation
messages: Membrane

358396:CHINAEXTREME RS15155
gene id: 358396:CHINAEXTREME_RS15155
uniprot id: M0LH20
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

358396:CHINAEXTREME RS11680
gene id: 358396:CHINAEXTREME_RS11680
uniprot id: M0L6H5
names: Similarity
messages: Belongs to the glutaredoxin family.

358396:CHINAEXTREME RS15195
gene id: 358396:CHINAEXTREME_RS15195
uniprot id: M0LFS9
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

358396:CHINAEXTREME RS14680
gene id: 358396:CHINAEXTREME_RS14680
uniprot id: M0L125
names: Similarity
messages: Belongs to the Nth/MutY family.

358396:CHINAEXTREME RS09845
gene id: 358396:CHINAEXTREME_RS09845
uniprot id: M0L9M3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

358396:CHINAEXTREME RS14510
gene id: 358396:CHINAEXTREME_RS14510
uniprot id: A0A1P8LWD0
names: Function
names: Similarity
messages: Belongs to the eukaryotic RecA-like protein family. RadB subfamily.
messages: Involved in DNA repair and in homologous recombination. May regulate the cleavage reactions of the branch-structured DNA. Has a very weak ATPase activity that is not stimulated by DNA. Binds DNA but does not promote DNA strands exchange.

358396:CHINAEXTREME RS00195
gene id: 358396:CHINAEXTREME_RS00195
uniprot id: A0A1P8LKF8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

358396:CHINAEXTREME RS10165
gene id: 358396:CHINAEXTREME_RS10165
uniprot id: M0L861
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus
messages: Repair polymerase that plays a key role in base-excision repair. Has 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity that removes the 5' sugar phosphate and also acts as a DNA polymerase that adds one nucleotide to the 3' end of the arising single-nucleotide gap. Conducts 'gap-filling' DNA synthesis in a stepwise distributive fashion rather than in a processive fashion as for other DNA polymerases.

358396:CHINAEXTREME RS16405
gene id: 358396:CHINAEXTREME_RS16405
uniprot id: M0LB85
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

358396:CHINAEXTREME RS09265
gene id: 358396:CHINAEXTREME_RS09265
uniprot id: M0L9C6
names: Similarity
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.

358396:CHINAEXTREME RS10855
gene id: 358396:CHINAEXTREME_RS10855
uniprot id: A0A1P8LR64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

358396:CHINAEXTREME RS07130
gene id: 358396:CHINAEXTREME_RS07130
uniprot id: M0LUE6
names: Subcellular Location Annotation
messages: Membrane

358396:CHINAEXTREME RS13995
gene id: 358396:CHINAEXTREME_RS13995
uniprot id: M0LGW0
names: Function
names: Similarity
messages: Belongs to the methylglyoxal synthase family.
messages: Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.

358396:CHINAEXTREME RS12700
gene id: 358396:CHINAEXTREME_RS12700
uniprot id: M0LFT4
names: Similarity
messages: Belongs to the transcriptional regulatory CopG/NikR family.

358396:CHINAEXTREME RS04780
gene id: 358396:CHINAEXTREME_RS04780
uniprot id: M0LMZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Cytoplasm

358396:CHINAEXTREME RS02910
gene id: 358396:CHINAEXTREME_RS02910
uniprot id: M0LSJ3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

358396:CHINAEXTREME RS10880
gene id: 358396:CHINAEXTREME_RS10880
uniprot id: M0L2V9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NucS endonuclease family.
messages: Cleaves both 3' and 5' ssDNA extremities of branched DNA structures.
messages: Cytoplasm

358396:CHINAEXTREME RS01795
gene id: 358396:CHINAEXTREME_RS01795
uniprot id: M0LJF9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CofC family.
messages: Guanylyltransferase that catalyzes the activation of (2S)-2-phospholactate (2-PL) as (2S)-lactyl-2-diphospho-5'-guanosine, via the condensation of 2-PL with GTP. It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor.
messages: Homodimer.

358396:CHINAEXTREME RS11310
gene id: 358396:CHINAEXTREME_RS11310
uniprot id: M0L4D8
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

358396:CHINAEXTREME RS13065
gene id: 358396:CHINAEXTREME_RS13065
uniprot id: M0LKK0
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

358396:CHINAEXTREME RS06505
gene id: 358396:CHINAEXTREME_RS06505
uniprot id: M0M0V0
names: Similarity
messages: Belongs to the PdaD family.

358396:CHINAEXTREME RS13910
gene id: 358396:CHINAEXTREME_RS13910
uniprot id: M0LFE5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

358396:CHINAEXTREME RS11830
gene id: 358396:CHINAEXTREME_RS11830
uniprot id: M0LGK1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the DNA photolyase class-1 family.
messages: Binds 1 5,10-methenyltetrahydrofolate (MTHF) per subunit.
messages: Binds 1 FAD per subunit.
messages: May have a photoreceptor function.

358396:CHINAEXTREME RS10105
gene id: 358396:CHINAEXTREME_RS10105
uniprot id: M0L6P5
names: Similarity
messages: Belongs to the transcriptional regulator TrmB family.

358396:CHINAEXTREME RS13915
gene id: 358396:CHINAEXTREME_RS13915
uniprot id: M0LGU4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: Binds to 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29.

358396:CHINAEXTREME RS17385
gene id: 358396:CHINAEXTREME_RS17385
uniprot id: M0LD94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

358396:CHINAEXTREME RS08335
gene id: 358396:CHINAEXTREME_RS08335
uniprot id: M0LV66
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

358396:CHINAEXTREME RS13825
gene id: 358396:CHINAEXTREME_RS13825
uniprot id: M0LJV4
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Part of the 30S ribosomal subunit. Contacts protein S4.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

358396:CHINAEXTREME RS20400
gene id: 358396:CHINAEXTREME_RS20400
uniprot id: M0LV97
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

358396:CHINAEXTREME RS06270
gene id: 358396:CHINAEXTREME_RS06270
uniprot id: M0LXX6
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

358396:CHINAEXTREME RS13135
gene id: 358396:CHINAEXTREME_RS13135
uniprot id: M0LKL4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 family.
messages: Catalyzes the cleavage of the N-glycosidic bond of deoxyribonucleoside 5'-monophosphates to yield deoxyribose 5-phosphate and a purine or pyrimidine base.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer and homodimer.

358396:CHINAEXTREME RS13400
gene id: 358396:CHINAEXTREME_RS13400
uniprot id: M0LHN1
names: Similarity
messages: Belongs to the peptidase C56 family.

358396:CHINAEXTREME RS07785
gene id: 358396:CHINAEXTREME_RS07785
uniprot id: M0LU03
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the protein kinase superfamily. BUD32 family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Component of the KEOPS complex that consists of Kae1, Bud32, Cgi121 and Pcc1; the whole complex dimerizes.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the protein kinase superfamily. Tyr protein kinase family. BUD32 subfamily.
messages: In the N-terminal section; belongs to the KAE1 / TsaD family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction. The Bud32 domain probably displays kinase activity that regulates Kae1 function.

358396:CHINAEXTREME RS15735
gene id: 358396:CHINAEXTREME_RS15735
uniprot id: M0LBJ0
names: Subcellular Location Annotation
messages: Membrane

358396:CHINAEXTREME RS02935
gene id: 358396:CHINAEXTREME_RS02935
uniprot id: M0LSJ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the archaeal dihydroneopterin aldolase family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin (H2Neo) to 6-hydroxymethyl-7,8-dihydropterin (6-HMD).
messages: Homotetramer.

358396:CHINAEXTREME RS14875
gene id: 358396:CHINAEXTREME_RS14875
uniprot id: M0LAB1
names: Function
names: Similarity
messages: Belongs to the archaeal 6-HMPDK family.
messages: Catalyzes the transfer of diphosphate from ATP to 6-hydroxymethyl-7,8-dihydropterin (6-HMD), leading to 6-hydroxymethyl-7,8-dihydropterin diphosphate (6-HMDP).

358396:CHINAEXTREME RS11305
gene id: 358396:CHINAEXTREME_RS11305
uniprot id: M0L2Z8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease activity. May be involved in RNA degradation.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Archaeal RNase J subfamily.
messages: Binds 2 Zn(2+) ions per subunit. It is not clear if Zn(2+) or Mg(2+) is physiologically important.
messages: Cytoplasm
messages: Homodimer.

358396:CHINAEXTREME RS08925
gene id: 358396:CHINAEXTREME_RS08925
uniprot id: A0A1P8LQ30
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

358396:CHINAEXTREME RS02370
gene id: 358396:CHINAEXTREME_RS02370
uniprot id: M0LG34
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

358396:CHINAEXTREME RS20645
gene id: 358396:CHINAEXTREME_RS20645
uniprot id: M0LZ34
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

358396:CHINAEXTREME RS09220
gene id: 358396:CHINAEXTREME_RS09220
uniprot id: M0L4N3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

358396:CHINAEXTREME RS04720
gene id: 358396:CHINAEXTREME_RS04720
uniprot id: M0LLQ8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IPP isomerase type 2 family.
messages: Cytoplasm
messages: Homooctamer. Dimer of tetramers.
messages: Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

358396:CHINAEXTREME RS03400
gene id: 358396:CHINAEXTREME_RS03400
uniprot id: M0LP73
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

358396:CHINAEXTREME RS19685
gene id: 358396:CHINAEXTREME_RS19685
uniprot id: M0LS76
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

358396:CHINAEXTREME RS04925
gene id: 358396:CHINAEXTREME_RS04925
uniprot id: M0LLQ7
names: Similarity
messages: Belongs to the phosphohexose mutase family.

358396:CHINAEXTREME RS08885
gene id: 358396:CHINAEXTREME_RS08885
uniprot id: M0L7T7
names: Similarity
messages: Belongs to the peptidase S8 family.

358396:CHINAEXTREME RS15985
gene id: 358396:CHINAEXTREME_RS15985
uniprot id: M0LE79
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

358396:CHINAEXTREME RS18175
gene id: 358396:CHINAEXTREME_RS18175
uniprot id: M0LRB6
names: Similarity
messages: Belongs to the AAA ATPase family. CDC48 subfamily.

358396:CHINAEXTREME RS04930
gene id: 358396:CHINAEXTREME_RS04930
uniprot id: A0A1P8LMY4
names: Similarity
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.

358396:CHINAEXTREME RS04120
gene id: 358396:CHINAEXTREME_RS04120
uniprot id: M0LMD2
names: Subcellular Location Annotation
messages: Membrane

358396:CHINAEXTREME RS08130
gene id: 358396:CHINAEXTREME_RS08130
uniprot id: M0LZI7
names: Similarity
messages: Belongs to the Ahb/Nir family.

358396:CHINAEXTREME RS09625
gene id: 358396:CHINAEXTREME_RS09625
uniprot id: M0L4U9
names: Similarity
messages: Belongs to the tRNA methyltransferase O family.

358396:CHINAEXTREME RS06500
gene id: 358396:CHINAEXTREME_RS06500
uniprot id: A0A1P8LNS8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase-20S proteasome association which triggers gate opening, and supports translocation of unfolded substrates.
messages: Belongs to the AAA ATPase family.
messages: Consists of three main regions, an N-terminal coiled-coil domain that may assist in substrate recognition, an interdomain involved in PAN hexamerization, and a C-terminal ATPase domain of the AAA type.
messages: Cytoplasm
messages: Homohexamer. The hexameric complex has a two-ring architecture resembling a top hat that caps the 20S proteasome core at one or both ends. Upon ATP-binding, the C-terminus of PAN interacts with the alpha-rings of the proteasome core by binding to the intersubunit pockets.

358396:CHINAEXTREME RS04655
gene id: 358396:CHINAEXTREME_RS04655
uniprot id: A0A1P8LW04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

358396:CHINAEXTREME RS14895
gene id: 358396:CHINAEXTREME_RS14895
uniprot id: M0L9E5
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.

358396:CHINAEXTREME RS12010
gene id: 358396:CHINAEXTREME_RS12010
uniprot id: M0LJJ0
names: Function
messages: Component of the dihydroxyacetone kinase complex, which is responsible for the phosphoenolpyruvate (PEP)-dependent phosphorylation of dihydroxyacetone. DhaM serves as the phosphoryl donor. Is phosphorylated by phosphoenolpyruvate in an EI- and HPr-dependent reaction, and a phosphorelay system on histidine residues finally leads to phosphoryl transfer to DhaL and dihydroxyacetone.

358396:CHINAEXTREME RS00690
gene id: 358396:CHINAEXTREME_RS00690
uniprot id: M0LHE6
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for chromosome condensation and partitioning.

358396:CHINAEXTREME RS19825
gene id: 358396:CHINAEXTREME_RS19825
uniprot id: M0LU66
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL43 family.
messages: Binds to the 23S rRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the 50S ribosomal subunit.

358396:CHINAEXTREME RS05765
gene id: 358396:CHINAEXTREME_RS05765
uniprot id: M0LL65
names: Function
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.

358396:CHINAEXTREME RS13560
gene id: 358396:CHINAEXTREME_RS13560
uniprot id: M0LF70
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein P1/P2 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the 50S ribosomal subunit. Homodimer, it forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Forms a heptameric L10(L12)2(L12)2(L12)2 complex, where L10 forms an elongated spine to which the L12 dimers bind in a sequential fashion.

358396:CHINAEXTREME RS15575
gene id: 358396:CHINAEXTREME_RS15575
uniprot id: M0LDN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 2 subfamily.
messages: Cytoplasm

358396:CHINAEXTREME RS02680
gene id: 358396:CHINAEXTREME_RS02680
uniprot id: M0LHQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NosZ family.
messages: Homodimer.
messages: In the C-terminal section; belongs to the cytochrome c oxidase subunit 2 family.
messages: Nitrous-oxide reductase is part of a bacterial respiratory system which is activated under anaerobic conditions in the presence of nitrate or nitrous oxide.
messages: Periplasm

358396:CHINAEXTREME RS02010
gene id: 358396:CHINAEXTREME_RS02010
uniprot id: M0LET4
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate.
messages: Belongs to the asparaginase 1 family. GatD subfamily.
messages: Heterodimer of GatD and GatE.

358396:CHINAEXTREME RS00580
gene id: 358396:CHINAEXTREME_RS00580
uniprot id: M0L2Q7
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

358396:CHINAEXTREME RS00065
gene id: 358396:CHINAEXTREME_RS00065
uniprot id: A0A1P8LKD5
names: Similarity
messages: Belongs to the glutamate synthase family.

358396:CHINAEXTREME RS09980
gene id: 358396:CHINAEXTREME_RS09980
uniprot id: M0L828
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

358396:CHINAEXTREME RS12555
gene id: 358396:CHINAEXTREME_RS12555
uniprot id: A0A1P8LRW7
names: Similarity
messages: Belongs to the phosphohexose mutase family.

358396:CHINAEXTREME RS12055
gene id: 358396:CHINAEXTREME_RS12055
uniprot id: M0LHY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC41A transporter family.
messages: Membrane

358396:CHINAEXTREME RS03270
gene id: 358396:CHINAEXTREME_RS03270
uniprot id: M0LP47
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.

358396:CHINAEXTREME RS05945
gene id: 358396:CHINAEXTREME_RS05945
uniprot id: M0LN11
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Cytoplasm
messages: The active site is a redox-active disulfide bond.

358396:CHINAEXTREME RS14590
gene id: 358396:CHINAEXTREME_RS14590
uniprot id: M0L4B7
names: Similarity
messages: Belongs to the TrpF family.

358396:CHINAEXTREME RS14845
gene id: 358396:CHINAEXTREME_RS14845
uniprot id: M0LAD4
names: Similarity
messages: Belongs to the DNA photolyase family.

358396:CHINAEXTREME RS03230
gene id: 358396:CHINAEXTREME_RS03230
uniprot id: M0LS31
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
messages: Cytoplasm
messages: Homotetramer.

358396:CHINAEXTREME RS10130
gene id: 358396:CHINAEXTREME_RS10130
uniprot id: M0L4S5
names: Similarity
messages: Belongs to the peptidase S1C family.

358396:CHINAEXTREME RS13895
gene id: 358396:CHINAEXTREME_RS13895
uniprot id: M0LIP5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head.
messages: Part of the 30S ribosomal subunit.

358396:CHINAEXTREME RS12785
gene id: 358396:CHINAEXTREME_RS12785
uniprot id: M0LFZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Membrane

358396:CHINAEXTREME RS11375
gene id: 358396:CHINAEXTREME_RS11375
uniprot id: M0L7P0
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS28 family.

358396:CHINAEXTREME RS11105
gene id: 358396:CHINAEXTREME_RS11105
uniprot id: M0L498
names: Similarity
messages: Belongs to the AAA ATPase family. CDC48 subfamily.

358396:CHINAEXTREME RS08000
gene id: 358396:CHINAEXTREME_RS08000
uniprot id: M0LVR8
names: Subcellular Location Annotation
messages: Membrane

358396:CHINAEXTREME RS04840
gene id: 358396:CHINAEXTREME_RS04840
uniprot id: M0LQZ2
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

358396:CHINAEXTREME RS09655
gene id: 358396:CHINAEXTREME_RS09655
uniprot id: M0L4T5
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

358396:CHINAEXTREME RS03600
gene id: 358396:CHINAEXTREME_RS03600
uniprot id: M0LQ93
names: Subcellular Location Annotation
messages: Membrane

358396:CHINAEXTREME RS06415
gene id: 358396:CHINAEXTREME_RS06415
uniprot id: M0LXV0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NAD to NADH.
messages: Homotetramer.

358396:CHINAEXTREME RS04610
gene id: 358396:CHINAEXTREME_RS04610
uniprot id: M0LMV8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase delta/II small subunit family.
messages: Heterodimer of a large subunit and a small subunit.
messages: Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase.

358396:CHINAEXTREME RS07790
gene id: 358396:CHINAEXTREME_RS07790
uniprot id: M0LXV8
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS31 family.
messages: Binds 1 zinc ion per subunit.
messages: Part of the 30S ribosomal subunit.

358396:CHINAEXTREME RS14490
gene id: 358396:CHINAEXTREME_RS14490
uniprot id: M0L0Y3
names: Similarity
messages: Belongs to the UPF0175 family.

358396:CHINAEXTREME RS15295
gene id: 358396:CHINAEXTREME_RS15295
uniprot id: A0A1P8LTD4
names: Function
names: Similarity
messages: Belongs to the TFIIB family.
messages: Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB).

358396:CHINAEXTREME RS19795
gene id: 358396:CHINAEXTREME_RS19795
uniprot id: M0LV30
names: Subcellular Location Annotation
messages: Membrane

358396:CHINAEXTREME RS14655
gene id: 358396:CHINAEXTREME_RS14655
uniprot id: M0L130
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family. N(4) subfamily.

358396:CHINAEXTREME RS02595
gene id: 358396:CHINAEXTREME_RS02595
uniprot id: M0LEJ4
names: Similarity
messages: Belongs to the thioesterase PaaI family.

358396:CHINAEXTREME RS10640
gene id: 358396:CHINAEXTREME_RS10640
uniprot id: M0L6Y6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

358396:CHINAEXTREME RS06970
gene id: 358396:CHINAEXTREME_RS06970
uniprot id: M0LXN0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CofE family.
messages: Binds 2 divalent metal cations per subunit. The ions could be magnesium and/or manganese.
messages: Catalyzes the GTP-dependent successive addition of two or more gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form coenzyme F420-0-glutamyl-glutamate (F420-2) or polyglutamated F420 derivatives.
messages: Homodimer.
messages: Monovalent cation. The ion could be potassium.

358396:CHINAEXTREME RS14050
gene id: 358396:CHINAEXTREME_RS14050
uniprot id: M0LGX0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

358396:CHINAEXTREME RS12845
gene id: 358396:CHINAEXTREME_RS12845
uniprot id: M0LJ69
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

358396:CHINAEXTREME RS05235
gene id: 358396:CHINAEXTREME_RS05235
uniprot id: M0LNL5
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Feedback inhibited by histidine.

358396:CHINAEXTREME RS12320
gene id: 358396:CHINAEXTREME_RS12320
uniprot id: A0A1P8LRT6
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

358396:CHINAEXTREME RS04200
gene id: 358396:CHINAEXTREME_RS04200
uniprot id: M0LNP7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. LysZ subfamily.
messages: Cytoplasm
messages: Involved in both the arginine and lysine biosynthetic pathways. Phosphorylates the LysW-bound precursors glutamate (for arginine biosynthesis), respectively alpha-aminoadipate (for lysine biosynthesis).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

358396:CHINAEXTREME RS04670
gene id: 358396:CHINAEXTREME_RS04670
uniprot id: M0LQW0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

358396:CHINAEXTREME RS04140
gene id: 358396:CHINAEXTREME_RS04140
uniprot id: M0LMJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

358396:CHINAEXTREME RS12520
gene id: 358396:CHINAEXTREME_RS12520
uniprot id: M0LHI4
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family.

358396:CHINAEXTREME RS01295
gene id: 358396:CHINAEXTREME_RS01295
uniprot id: M0LF61
names: Subcellular Location Annotation
messages: Membrane

358396:CHINAEXTREME RS19225
gene id: 358396:CHINAEXTREME_RS19225
uniprot id: M0LR44
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

358396:CHINAEXTREME RS12115
gene id: 358396:CHINAEXTREME_RS12115
uniprot id: M0LLD1
names: Similarity
names: Subunit
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
messages: Heterooligomer of catalytic and regulatory chains.

358396:CHINAEXTREME RS16195
gene id: 358396:CHINAEXTREME_RS16195
uniprot id: M0LEC1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic/archaeal RNase P protein component 3 family.
messages: Consists of a catalytic RNA component and at least 4-5 protein subunits.
messages: Cytoplasm
messages: Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.

358396:CHINAEXTREME RS01120
gene id: 358396:CHINAEXTREME_RS01120
uniprot id: M0LF99
names: Similarity
names: Subunit
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
messages: Homotetramer. Residues from neighboring subunits contribute catalytic and substrate-binding residues to each active site.

358396:CHINAEXTREME RS10315
gene id: 358396:CHINAEXTREME_RS10315
uniprot id: M0L889
names: Caution
names: Function
names: Similarity
messages: Belongs to the Nre family.
messages: Involved in DNA damage repair.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

358396:CHINAEXTREME RS13880
gene id: 358396:CHINAEXTREME_RS13880
uniprot id: M0LFH1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

358396:CHINAEXTREME RS04395
gene id: 358396:CHINAEXTREME_RS04395
uniprot id: M0LRU2
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

358396:CHINAEXTREME RS07890
gene id: 358396:CHINAEXTREME_RS07890
uniprot id: M0LZL9
names: Similarity
messages: Belongs to the CutA family.

358396:CHINAEXTREME RS11255
gene id: 358396:CHINAEXTREME_RS11255
uniprot id: M0L322
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

358396:CHINAEXTREME RS01395
gene id: 358396:CHINAEXTREME_RS01395
uniprot id: M0LF40
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the YjjX NTPase family.
messages: Binds 1 divalent metal cation per subunit; can use either Mg(2+) or Mn(2+).
messages: Homodimer.
messages: Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA/RNA precursor pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

358396:CHINAEXTREME RS13585
gene id: 358396:CHINAEXTREME_RS13585
uniprot id: M0LF75
names: Similarity
messages: Belongs to the CutA family.

358396:CHINAEXTREME RS17980
gene id: 358396:CHINAEXTREME_RS17980
uniprot id: M0LGX1
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

358396:CHINAEXTREME RS16265
gene id: 358396:CHINAEXTREME_RS16265
uniprot id: M0LED7
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

358396:CHINAEXTREME RS06865
gene id: 358396:CHINAEXTREME_RS06865
uniprot id: M0LXP7
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

358396:CHINAEXTREME RS09595
gene id: 358396:CHINAEXTREME_RS09595
uniprot id: M0L9I3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic release factor 1 family. Pelota subfamily.
messages: Cytoplasm
messages: May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA. May play a role in the release non-functional ribosomes and degradation of damaged mRNAs. Has endoribonuclease activity.
messages: Monomer.
messages: The N-terminal domain has the RNA-binding Sm fold. It harbors the endoribonuclease activity.

358396:CHINAEXTREME RS16930
gene id: 358396:CHINAEXTREME_RS16930
uniprot id: M0LS02
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

358396:CHINAEXTREME RS06545
gene id: 358396:CHINAEXTREME_RS06545
uniprot id: M0LXS3
names: Function
names: Similarity
messages: Belongs to the V-ATPase F subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

358396:CHINAEXTREME RS18740
gene id: 358396:CHINAEXTREME_RS18740
uniprot id: M0LTW7
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

358396:CHINAEXTREME RS01695
gene id: 358396:CHINAEXTREME_RS01695
uniprot id: M0LJH9
names: Similarity
messages: Belongs to the HMG-CoA reductase family.

358396:CHINAEXTREME RS08250
gene id: 358396:CHINAEXTREME_RS08250
uniprot id: M0LVJ9
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

358396:CHINAEXTREME RS05330
gene id: 358396:CHINAEXTREME_RS05330
uniprot id: M0LLU5
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

358396:CHINAEXTREME RS00815
gene id: 358396:CHINAEXTREME_RS00815
uniprot id: M0LIL1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

358396:CHINAEXTREME RS00760
gene id: 358396:CHINAEXTREME_RS00760
uniprot id: M0LE41
names: Subcellular Location Annotation
messages: Membrane

358396:CHINAEXTREME RS15540
gene id: 358396:CHINAEXTREME_RS15540
uniprot id: M0LCA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane

358396:CHINAEXTREME RS09320
gene id: 358396:CHINAEXTREME_RS09320
uniprot id: A0A1P8LW83
names: Subcellular Location Annotation
messages: Membrane

358396:CHINAEXTREME RS13325
gene id: 358396:CHINAEXTREME_RS13325
uniprot id: M0LHL8
names: Similarity
messages: Belongs to the UPF0145 family.

358396:CHINAEXTREME RS04795
gene id: 358396:CHINAEXTREME_RS04795
uniprot id: M0LLS3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. Archaeal SRP consists of a 7S RNA molecule of 300 nucleotides and two protein subunits: SRP54 and SRP19.

358396:CHINAEXTREME RS05290
gene id: 358396:CHINAEXTREME_RS05290
uniprot id: A0A1P8LN51
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase Z family.
messages: Binds 2 Zn(2+) ions.
messages: Homodimer.
messages: Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.

358396:CHINAEXTREME RS17760
gene id: 358396:CHINAEXTREME_RS17760
uniprot id: M0LDH7
names: Similarity
messages: Belongs to the peptidase S45 family.

358396:CHINAEXTREME RS09570
gene id: 358396:CHINAEXTREME_RS09570
uniprot id: M0L9H9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

358396:CHINAEXTREME RS13580
gene id: 358396:CHINAEXTREME_RS13580
uniprot id: M0LFA8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

358396:CHINAEXTREME RS03930
gene id: 358396:CHINAEXTREME_RS03930
uniprot id: M0LQF9
names: Subcellular Location Annotation
messages: Membrane

358396:CHINAEXTREME RS18970
gene id: 358396:CHINAEXTREME_RS18970
uniprot id: M0LSH9
names: Function
names: Similarity
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. Archaeal HPRT subfamily.
messages: May catalyze a purine salvage reaction, the substrate is unknown.

358396:CHINAEXTREME RS13870
gene id: 358396:CHINAEXTREME_RS13870
uniprot id: M0LIN9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: Located at the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

358396:CHINAEXTREME RS12545
gene id: 358396:CHINAEXTREME_RS12545
uniprot id: M0LHI8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

358396:CHINAEXTREME RS14120
gene id: 358396:CHINAEXTREME_RS14120
uniprot id: M0LFI7
names: Function
names: Similarity
messages: Belongs to the TFIIB family.
messages: Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB).

358396:CHINAEXTREME RS03355
gene id: 358396:CHINAEXTREME_RS03355
uniprot id: M0LR18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCM family.
messages: Nucleus

358396:CHINAEXTREME RS14010
gene id: 358396:CHINAEXTREME_RS14010
uniprot id: M0LFJ6
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

358396:CHINAEXTREME RS02125
gene id: 358396:CHINAEXTREME_RS02125
uniprot id: M0LJA1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NadC/ModD family.
messages: Hexamer formed by 3 homodimers.
messages: Involved in the catabolism of quinolinic acid (QA).

358396:CHINAEXTREME RS16230
gene id: 358396:CHINAEXTREME_RS16230
uniprot id: A0A1P8LWE2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

358396:CHINAEXTREME RS15780
gene id: 358396:CHINAEXTREME_RS15780
uniprot id: M0LET0
names: Function
messages: Part of a potassium transport system.

358396:CHINAEXTREME RS09185
gene id: 358396:CHINAEXTREME_RS09185
uniprot id: M0L7R4
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

358396:CHINAEXTREME RS11465
gene id: 358396:CHINAEXTREME_RS11465
uniprot id: M0L354
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

358396:CHINAEXTREME RS06990
gene id: 358396:CHINAEXTREME_RS06990
uniprot id: M0LYB0
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

358396:CHINAEXTREME RS19030
gene id: 358396:CHINAEXTREME_RS19030
uniprot id: M0LRI5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the transcriptional regulatory CopG/NikR family.
messages: Binds 1 nickel ion per subunit.
messages: Transcriptional regulator.

358396:CHINAEXTREME RS09395
gene id: 358396:CHINAEXTREME_RS09395
uniprot id: M0L9E9
names: Subcellular Location Annotation
messages: Membrane

358396:CHINAEXTREME RS12485
gene id: 358396:CHINAEXTREME_RS12485
uniprot id: M0LHS2
names: Similarity
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the malic enzymes family.

358396:CHINAEXTREME RS18255
gene id: 358396:CHINAEXTREME_RS18255
uniprot id: M0LPX4
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reduced FMN (FMNH(2)).

358396:CHINAEXTREME RS15510
gene id: 358396:CHINAEXTREME_RS15510
uniprot id: M0LGU7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThiI family.
messages: Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

358396:CHINAEXTREME RS08205
gene id: 358396:CHINAEXTREME_RS08205
uniprot id: M0LZH4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

358396:CHINAEXTREME RS15545
gene id: 358396:CHINAEXTREME_RS15545
uniprot id: M0LCC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Membrane

358396:CHINAEXTREME RS03460
gene id: 358396:CHINAEXTREME_RS03460
uniprot id: M0LRB7
names: Similarity
messages: Belongs to the carotenoid oxygenase family.

358396:CHINAEXTREME RS16385
gene id: 358396:CHINAEXTREME_RS16385
uniprot id: M0LCH5
names: Similarity
messages: Belongs to the SCO1/2 family.

358396:CHINAEXTREME RS10400
gene id: 358396:CHINAEXTREME_RS10400
uniprot id: M0L3J4
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

358396:CHINAEXTREME RS10925
gene id: 358396:CHINAEXTREME_RS10925
uniprot id: M0L5Z2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CbbQ/NirQ/NorQ/GpvN family.
messages: Vesicle
messages: gas vesicle

358396:CHINAEXTREME RS01780
gene id: 358396:CHINAEXTREME_RS01780
uniprot id: M0LGC9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. CofG family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated synthesis of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (FO) from 5-amino-5-(4-hydroxybenzyl)-6-(D-ribitylimino)-5,6-dihydrouracil.
messages: The FO synthase complex consists of two subunits, CofG and CofH.

358396:CHINAEXTREME RS11950
gene id: 358396:CHINAEXTREME_RS11950
uniprot id: A0A1P8LRP8
names: Similarity
messages: Belongs to the AOR/FOR family.

358396:CHINAEXTREME RS07895
gene id: 358396:CHINAEXTREME_RS07895
uniprot id: M0LYZ2
names: Subcellular Location Annotation
messages: Cytoplasm

358396:CHINAEXTREME RS08210
gene id: 358396:CHINAEXTREME_RS08210
uniprot id: M0LYU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ModE family.
messages: Membrane

358396:CHINAEXTREME RS18410
gene id: 358396:CHINAEXTREME_RS18410
uniprot id: M0LPU9
names: Subcellular Location Annotation
messages: Membrane

358396:CHINAEXTREME RS06825
gene id: 358396:CHINAEXTREME_RS06825
uniprot id: M0LU81
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.

358396:CHINAEXTREME RS12535
gene id: 358396:CHINAEXTREME_RS12535
uniprot id: M0LM28
names: Subcellular Location Annotation
messages: Membrane

358396:CHINAEXTREME RS04445
gene id: 358396:CHINAEXTREME_RS04445
uniprot id: M0LRV3
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

358396:CHINAEXTREME RS19835
gene id: 358396:CHINAEXTREME_RS19835
uniprot id: M0LQT7
names: Similarity
messages: Belongs to the CTAG/PCC1 family.

358396:CHINAEXTREME RS13920
gene id: 358396:CHINAEXTREME_RS13920
uniprot id: M0LIQ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

358396:CHINAEXTREME RS10730
gene id: 358396:CHINAEXTREME_RS10730
uniprot id: M0L3V1
names: Subcellular Location Annotation
messages: Membrane

358396:CHINAEXTREME RS20715
gene id: 358396:CHINAEXTREME_RS20715
uniprot id: A0A1P8LWR7
names: Similarity
messages: In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.
messages: In the central section; belongs to the CRISPR-associated helicase Cas3 family.

358396:CHINAEXTREME RS00640
gene id: 358396:CHINAEXTREME_RS00640
uniprot id: M0L1C9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

358396:CHINAEXTREME RS17540
gene id: 358396:CHINAEXTREME_RS17540
uniprot id: M0LHV9
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Heterodimer composed of a glutamine amidotransferase subunit (A) and a GMP-binding subunit (B).

358396:CHINAEXTREME RS01800
gene id: 358396:CHINAEXTREME_RS01800
uniprot id: M0LI91
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CetZ family.
messages: Cytoplasm
messages: Involved in cell shape control.

358396:CHINAEXTREME RS02555
gene id: 358396:CHINAEXTREME_RS02555
uniprot id: M0LHU7
names: Similarity
messages: Belongs to the TPP enzyme family.

358396:CHINAEXTREME RS00635
gene id: 358396:CHINAEXTREME_RS00635
uniprot id: M0L2P7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

358396:CHINAEXTREME RS07490
gene id: 358396:CHINAEXTREME_RS07490
uniprot id: M0LV12
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

358396:CHINAEXTREME RS09105
gene id: 358396:CHINAEXTREME_RS09105
uniprot id: M0LB68
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

358396:CHINAEXTREME RS00570
gene id: 358396:CHINAEXTREME_RS00570
uniprot id: M0L5W2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

358396:CHINAEXTREME RS02300
gene id: 358396:CHINAEXTREME_RS02300
uniprot id: M0LEN4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

358396:CHINAEXTREME RS10340
gene id: 358396:CHINAEXTREME_RS10340
uniprot id: M0L893
names: Function
names: Similarity
messages: Belongs to the HARP family.
messages: RNA-free RNase P that catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus.

358396:CHINAEXTREME RS18245
gene id: 358396:CHINAEXTREME_RS18245
uniprot id: M0LTA7
names: Similarity
messages: Belongs to the PHP hydrolase family. HisK subfamily.

358396:CHINAEXTREME RS15710
gene id: 358396:CHINAEXTREME_RS15710
uniprot id: M0LBI5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

358396:CHINAEXTREME RS20195
gene id: 358396:CHINAEXTREME_RS20195
uniprot id: M0LQL7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

358396:CHINAEXTREME RS08920
gene id: 358396:CHINAEXTREME_RS08920
uniprot id: M0L9L6
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

358396:CHINAEXTREME RS09250
gene id: 358396:CHINAEXTREME_RS09250
uniprot id: M0L4M0
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL15 family.

358396:CHINAEXTREME RS00310
gene id: 358396:CHINAEXTREME_RS00310
uniprot id: A0A1P8LKH3
names: Similarity
messages: Belongs to the SAM hydrolase / SAM-dependent halogenase family.

358396:CHINAEXTREME RS06620
gene id: 358396:CHINAEXTREME_RS06620
uniprot id: M0LVH1
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

358396:CHINAEXTREME RS10270
gene id: 358396:CHINAEXTREME_RS10270
uniprot id: M0L3K9
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

358396:CHINAEXTREME RS01820
gene id: 358396:CHINAEXTREME_RS01820
uniprot id: M0LJF3
names: Function
messages: Part of a potassium transport system.

358396:CHINAEXTREME RS17470
gene id: 358396:CHINAEXTREME_RS17470
uniprot id: M0LDA8
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

358396:CHINAEXTREME RS20110
gene id: 358396:CHINAEXTREME_RS20110
uniprot id: M0LS03
names: Similarity
messages: Belongs to the complex I subunit 3 family.

358396:CHINAEXTREME RS07205
gene id: 358396:CHINAEXTREME_RS07205
uniprot id: M0LUD4
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

358396:CHINAEXTREME RS13125
gene id: 358396:CHINAEXTREME_RS13125
uniprot id: M0LHJ0
names: Subcellular Location Annotation
messages: Membrane

358396:CHINAEXTREME RS20060
gene id: 358396:CHINAEXTREME_RS20060
uniprot id: M0LS12
names: Subcellular Location Annotation
messages: Membrane

358396:CHINAEXTREME RS00205
gene id: 358396:CHINAEXTREME_RS00205
uniprot id: A0A1P8LW07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

358396:CHINAEXTREME RS01585
gene id: 358396:CHINAEXTREME_RS01585
uniprot id: M0LGG6
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

358396:CHINAEXTREME RS07065
gene id: 358396:CHINAEXTREME_RS07065
uniprot id: M0LXL6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EIF2G subfamily.
messages: Heterotrimer composed of an alpha, a beta and a gamma chain.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA.

358396:CHINAEXTREME RS13815
gene id: 358396:CHINAEXTREME_RS13815
uniprot id: M0LGS1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

358396:CHINAEXTREME RS02115
gene id: 358396:CHINAEXTREME_RS02115
uniprot id: M0LER6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 3 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

358396:CHINAEXTREME RS00220
gene id: 358396:CHINAEXTREME_RS00220
uniprot id: M0LVH8
names: Subcellular Location Annotation
messages: Membrane

358396:CHINAEXTREME RS10465
gene id: 358396:CHINAEXTREME_RS10465
uniprot id: M0L8B7
names: Function
messages: Part of a potassium transport system.

358396:CHINAEXTREME RS15500
gene id: 358396:CHINAEXTREME_RS15500
uniprot id: M0LDL6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urocanase family.
messages: Binds 1 NAD(+) per subunit.
messages: Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

358396:CHINAEXTREME RS07925
gene id: 358396:CHINAEXTREME_RS07925
uniprot id: A0A1P8LPJ1
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

358396:CHINAEXTREME RS00255
gene id: 358396:CHINAEXTREME_RS00255
uniprot id: A0A1P8LKG3
names: Similarity
messages: Belongs to the TrpC family.

358396:CHINAEXTREME RS06815
gene id: 358396:CHINAEXTREME_RS06815
uniprot id: M0LXQ6
names: Similarity
messages: Belongs to the UPF0215 family.

358396:CHINAEXTREME RS03800
gene id: 358396:CHINAEXTREME_RS03800
uniprot id: M0LM61
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

358396:CHINAEXTREME RS18895
gene id: 358396:CHINAEXTREME_RS18895
uniprot id: M0LR97
names: Subcellular Location Annotation
messages: Membrane

358396:CHINAEXTREME RS18575
gene id: 358396:CHINAEXTREME_RS18575
uniprot id: M0LR48
names: Domain
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the CobB/CbiA family.
messages: Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source.
messages: Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP and cobyrinate and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.
messages: The a and c carboxylates of cobyrinate are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CbiA catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate.

358396:CHINAEXTREME RS03905
gene id: 358396:CHINAEXTREME_RS03905
uniprot id: M0LQF4
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

358396:CHINAEXTREME RS08625
gene id: 358396:CHINAEXTREME_RS08625
uniprot id: M0LW77
names: Subcellular Location Annotation
messages: Membrane

358396:CHINAEXTREME RS08860
gene id: 358396:CHINAEXTREME_RS08860
uniprot id: M0L7T3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

358396:CHINAEXTREME RS05470
gene id: 358396:CHINAEXTREME_RS05470
uniprot id: M0LMS4
names: Similarity
messages: Belongs to the phosphohexose mutase family.

358396:CHINAEXTREME RS02665
gene id: 358396:CHINAEXTREME_RS02665
uniprot id: M0LEG3
names: Similarity
messages: Belongs to the serpin family.

358396:CHINAEXTREME RS12820
gene id: 358396:CHINAEXTREME_RS12820
uniprot id: M0LHB1
names: Function
names: Similarity
messages: Belongs to the ATP-dependent DNA ligase family.
messages: DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair.

358396:CHINAEXTREME RS04070
gene id: 358396:CHINAEXTREME_RS04070
uniprot id: M0LMC2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

358396:CHINAEXTREME RS13250
gene id: 358396:CHINAEXTREME_RS13250
uniprot id: A0A1P8LSB4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

358396:CHINAEXTREME RS00300
gene id: 358396:CHINAEXTREME_RS00300
uniprot id: M0L1L0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Degrades polypeptides processively.
messages: Belongs to the peptidase S16 family. Archaeal LonB subfamily.
messages: Cell membrane
messages: Homohexamer. Organized in a ring with a central cavity.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

358396:CHINAEXTREME RS18420
gene id: 358396:CHINAEXTREME_RS18420
uniprot id: M0LU18
names: Subcellular Location Annotation
messages: Cytoplasm

358396:CHINAEXTREME RS17360
gene id: 358396:CHINAEXTREME_RS17360
uniprot id: M0LD90
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

358396:CHINAEXTREME RS05455
gene id: 358396:CHINAEXTREME_RS05455
uniprot id: M0LJQ3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class III (archaeal) subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

358396:CHINAEXTREME RS05255
gene id: 358396:CHINAEXTREME_RS05255
uniprot id: M0LLT6
names: Caution
names: Function
names: Similarity
messages: Belongs to the TBP family.
messages: General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

358396:CHINAEXTREME RS15995
gene id: 358396:CHINAEXTREME_RS15995
uniprot id: M0LAY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

358396:CHINAEXTREME RS14075
gene id: 358396:CHINAEXTREME_RS14075
uniprot id: M0LGX6
names: Similarity
messages: Belongs to the AAA ATPase family. CDC48 subfamily.

358396:CHINAEXTREME RS11240
gene id: 358396:CHINAEXTREME_RS11240
uniprot id: M0L661
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal Rpo3/eukaryotic RPB3 RNA polymerase subunit family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the RNA polymerase complex.

358396:CHINAEXTREME RS16940
gene id: 358396:CHINAEXTREME_RS16940
uniprot id: M0LNT6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the THI4 family.
messages: Homooctamer; tetramer of dimers.
messages: Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

358396:CHINAEXTREME RS11135
gene id: 358396:CHINAEXTREME_RS11135
uniprot id: M0L640
names: Similarity
messages: Belongs to the NtaA/SnaA/DszA monooxygenase family.

358396:CHINAEXTREME RS09295
gene id: 358396:CHINAEXTREME_RS09295
uniprot id: M0L4P7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AP endonuclease 2 family.
messages: Binds 3 Zn(2+) ions.
messages: Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.

358396:CHINAEXTREME RS03260
gene id: 358396:CHINAEXTREME_RS03260
uniprot id: M0LMZ3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

358396:CHINAEXTREME RS03310
gene id: 358396:CHINAEXTREME_RS03310
uniprot id: M0LN03
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

358396:CHINAEXTREME RS12795
gene id: 358396:CHINAEXTREME_RS12795
uniprot id: A0A1P8LS38
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CofD family.
messages: Catalyzes the transfer of the 2-phospholactate moiety from (2S)-lactyl-2-diphospho-5'-guanosine to 7,8-didemethyl-8-hydroxy-5-deazariboflavin (FO) with the formation of oxidized coenzyme F420-0 and GMP.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

358396:CHINAEXTREME RS09575
gene id: 358396:CHINAEXTREME_RS09575
uniprot id: A0A1P8LQE4
names: Similarity
messages: Belongs to the UPF0045 family.

358396:CHINAEXTREME RS13545
gene id: 358396:CHINAEXTREME_RS13545
uniprot id: M0LG75
names: Subcellular Location Annotation
messages: Membrane

358396:CHINAEXTREME RS11270
gene id: 358396:CHINAEXTREME_RS11270
uniprot id: M0L667
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal Rpo6/eukaryotic RPB6 RNA polymerase subunit family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

358396:CHINAEXTREME RS02325
gene id: 358396:CHINAEXTREME_RS02325
uniprot id: M0LEN0
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

358396:CHINAEXTREME RS00030
gene id: 358396:CHINAEXTREME_RS00030
uniprot id: M0LVM0
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

358396:CHINAEXTREME RS07315
gene id: 358396:CHINAEXTREME_RS07315
uniprot id: M0LV62
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal/bacterial/fungal opsin family.
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

358396:CHINAEXTREME RS10185
gene id: 358396:CHINAEXTREME_RS10185
uniprot id: M0L6Q8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

358396:CHINAEXTREME RS07295
gene id: 358396:CHINAEXTREME_RS07295
uniprot id: M0LV62
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal/bacterial/fungal opsin family.
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

358396:CHINAEXTREME RS07015
gene id: 358396:CHINAEXTREME_RS07015
uniprot id: M0LYA5
names: Similarity
messages: Belongs to the SUI1 family.

358396:CHINAEXTREME RS07080
gene id: 358396:CHINAEXTREME_RS07080
uniprot id: M0LUF2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the archaeal Spt4 family.
messages: Heterodimer composed of Spt4 and Spt5.
messages: Stimulates transcription elongation.

358396:CHINAEXTREME RS09990
gene id: 358396:CHINAEXTREME_RS09990
uniprot id: M0L3C5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic RPB4 RNA polymerase subunit family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. This subunit is less well bound than the others.
messages: Part of the RNA polymerase complex. Forms a stalk with Rpo7 that extends from the main structure.

358396:CHINAEXTREME RS02500
gene id: 358396:CHINAEXTREME_RS02500
uniprot id: M0LEN3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

358396:CHINAEXTREME RS04810
gene id: 358396:CHINAEXTREME_RS04810
uniprot id: M0LPS3
names: Similarity
messages: Belongs to the UPF0201 family.

358396:CHINAEXTREME RS07510
gene id: 358396:CHINAEXTREME_RS07510
uniprot id: M0LY14
names: Similarity
messages: Belongs to the RutC family.

358396:CHINAEXTREME RS04205
gene id: 358396:CHINAEXTREME_RS04205
uniprot id: M0LQL5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. LysY sub-subfamily.
messages: Cytoplasm
messages: Involved in both the arginine and lysine biosynthetic pathways.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

358396:CHINAEXTREME RS11020
gene id: 358396:CHINAEXTREME_RS11020
uniprot id: M0L483
names: Subcellular Location Annotation
messages: Membrane

358396:CHINAEXTREME RS00060
gene id: 358396:CHINAEXTREME_RS00060
uniprot id: M0LTC9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.
messages: Cytoplasm
messages: Homodimer.

358396:CHINAEXTREME RS08650
gene id: 358396:CHINAEXTREME_RS08650
uniprot id: M0L6S3
names: Cofactor
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Binds 1 zinc ion per subunit. The zinc ion is important for the structural integrity of the protein.

358396:CHINAEXTREME RS19100
gene id: 358396:CHINAEXTREME_RS19100
uniprot id: M0LR66
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

358396:CHINAEXTREME RS09685
gene id: 358396:CHINAEXTREME_RS09685
uniprot id: A0A1P8LQG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

358396:CHINAEXTREME RS05510
gene id: 358396:CHINAEXTREME_RS05510
uniprot id: M0LJG0
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

358396:CHINAEXTREME RS15330
gene id: 358396:CHINAEXTREME_RS15330
uniprot id: A0A1P8LTG9
names: Subunit
messages: Homotrimer.

358396:CHINAEXTREME RS01315
gene id: 358396:CHINAEXTREME_RS01315
uniprot id: M0LH34
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).

358396:CHINAEXTREME RS09940
gene id: 358396:CHINAEXTREME_RS09940
uniprot id: M0L5V6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

358396:CHINAEXTREME RS09205
gene id: 358396:CHINAEXTREME_RS09205
uniprot id: A0A1P8LW92
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

358396:CHINAEXTREME RS09130
gene id: 358396:CHINAEXTREME_RS09130
uniprot id: M0LB73
names: Function
names: Similarity
messages: Belongs to the archaeal SPP-like hydrolase family.
messages: Catalyzes the dephosphorylation of 2-phosphoglycolate.

358396:CHINAEXTREME RS16875
gene id: 358396:CHINAEXTREME_RS16875
uniprot id: M0LSY1
names: Similarity
messages: Belongs to the DNA polymerase type-B family.

358396:CHINAEXTREME RS04380
gene id: 358396:CHINAEXTREME_RS04380
uniprot id: M0LMI8
names: Subcellular Location Annotation
messages: Membrane

358396:CHINAEXTREME RS06895
gene id: 358396:CHINAEXTREME_RS06895
uniprot id: M0LXP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA-PH family.
messages: Cytoplasm

358396:CHINAEXTREME RS04460
gene id: 358396:CHINAEXTREME_RS04460
uniprot id: M0LNV0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the activator 1 small subunits family. RfcS subfamily.
messages: Heteromultimer composed of small subunits (RfcS) and large subunits (RfcL).
messages: Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA.

358396:CHINAEXTREME RS13320
gene id: 358396:CHINAEXTREME_RS13320
uniprot id: M0LG39
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

358396:CHINAEXTREME RS15305
gene id: 358396:CHINAEXTREME_RS15305
uniprot id: A0A1P8LTD3
names: Subunit
messages: Homotrimer.

358396:CHINAEXTREME RS14755
gene id: 358396:CHINAEXTREME_RS14755
uniprot id: M0LEY1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

358396:CHINAEXTREME RS05940
gene id: 358396:CHINAEXTREME_RS05940
uniprot id: A0A1P8LNH4
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

358396:CHINAEXTREME RS17845
gene id: 358396:CHINAEXTREME_RS17845
uniprot id: M0LGU6
names: Similarity
messages: Belongs to the UPF0047 family.

358396:CHINAEXTREME RS06615
gene id: 358396:CHINAEXTREME_RS06615
uniprot id: M0LXT6
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

358396:CHINAEXTREME RS05350
gene id: 358396:CHINAEXTREME_RS05350
uniprot id: M0LKC5
names: Subcellular Location Annotation
messages: Membrane

358396:CHINAEXTREME RS09935
gene id: 358396:CHINAEXTREME_RS09935
uniprot id: M0L4G4
names: Subcellular Location Annotation
messages: Membrane

358396:CHINAEXTREME RS09670
gene id: 358396:CHINAEXTREME_RS09670
uniprot id: M0L9J5
names: Similarity
messages: Belongs to the HypE family.

358396:CHINAEXTREME RS15210
gene id: 358396:CHINAEXTREME_RS15210
uniprot id: M0LCK7
names: Similarity
messages: Belongs to the anthranilate synthase component I family.
messages: Belongs to the isochorismate synthase family.

358396:CHINAEXTREME RS01160
gene id: 358396:CHINAEXTREME_RS01160
uniprot id: M0LDV8
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

358396:CHINAEXTREME RS20610
gene id: 358396:CHINAEXTREME_RS20610
uniprot id: A0A1P8LWP8
names: Subcellular Location Annotation
messages: Membrane

358396:CHINAEXTREME RS05370
gene id: 358396:CHINAEXTREME_RS05370
uniprot id: M0LKM0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane
messages: Potential transporter for phosphate.

358396:CHINAEXTREME RS05720
gene id: 358396:CHINAEXTREME_RS05720
uniprot id: M0LMX0
names: Function
messages: Protects DNA against thermal denaturation and modulates transcription.

358396:CHINAEXTREME RS15160
gene id: 358396:CHINAEXTREME_RS15160
uniprot id: M0LCH8
names: Subcellular Location Annotation
messages: Membrane

358396:CHINAEXTREME RS01215
gene id: 358396:CHINAEXTREME_RS01215
uniprot id: M0LH52
names: Subcellular Location Annotation
messages: Cytoplasm

358396:CHINAEXTREME RS16670
gene id: 358396:CHINAEXTREME_RS16670
uniprot id: M0LBC8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

358396:CHINAEXTREME RS19635
gene id: 358396:CHINAEXTREME_RS19635
uniprot id: M0LS83
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

358396:CHINAEXTREME RS05365
gene id: 358396:CHINAEXTREME_RS05365
uniprot id: M0LPV4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane
messages: Potential transporter for phosphate.

358396:CHINAEXTREME RS10330
gene id: 358396:CHINAEXTREME_RS10330
uniprot id: M0L4W0
names: Function
names: Similarity
messages: Belongs to the EF-1-beta/EF-1-delta family.
messages: Promotes the exchange of GDP for GTP in EF-1-alpha/GDP, thus allowing the regeneration of EF-1-alpha/GTP that could then be used to form the ternary complex EF-1-alpha/GTP/AAtRNA.

358396:CHINAEXTREME RS12490
gene id: 358396:CHINAEXTREME_RS12490
uniprot id: M0LHH9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic CoaD family.
messages: Cytoplasm
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

358396:CHINAEXTREME RS09425
gene id: 358396:CHINAEXTREME_RS09425
uniprot id: M0L4S0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

358396:CHINAEXTREME RS05110
gene id: 358396:CHINAEXTREME_RS05110
uniprot id: M0LPS2
names: Function
names: Similarity
messages: Belongs to the eukaryotic RecA-like protein family.
messages: Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules.

358396:CHINAEXTREME RS16630
gene id: 358396:CHINAEXTREME_RS16630
uniprot id: A0A1P8LU33
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

358396:CHINAEXTREME RS07420
gene id: 358396:CHINAEXTREME_RS07420
uniprot id: M0LV44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamine synthetase family.
messages: Cytoplasm

358396:CHINAEXTREME RS09420
gene id: 358396:CHINAEXTREME_RS09420
uniprot id: M0L9F3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

358396:CHINAEXTREME RS07155
gene id: 358396:CHINAEXTREME_RS07155
uniprot id: M0LUE2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

358396:CHINAEXTREME RS03280
gene id: 358396:CHINAEXTREME_RS03280
uniprot id: M0LS43
names: Subcellular Location Annotation
messages: Membrane

358396:CHINAEXTREME RS12950
gene id: 358396:CHINAEXTREME_RS12950
uniprot id: M0LFZ1
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

358396:CHINAEXTREME RS07595
gene id: 358396:CHINAEXTREME_RS07595
uniprot id: M0LUZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Cytoplasm

358396:CHINAEXTREME RS08815
gene id: 358396:CHINAEXTREME_RS08815
uniprot id: M0LB18
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eIF-2-beta/eIF-5 family.
messages: Heterotrimer composed of an alpha, a beta and a gamma chain.
messages: eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA.

358396:CHINAEXTREME RS16650
gene id: 358396:CHINAEXTREME_RS16650
uniprot id: A0A1P8LU32
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

358396:CHINAEXTREME RS02510
gene id: 358396:CHINAEXTREME_RS02510
uniprot id: M0LHW6
names: Similarity
messages: Belongs to the thioesterase PaaI family.

358396:CHINAEXTREME RS17660
gene id: 358396:CHINAEXTREME_RS17660
uniprot id: M0LDE2
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

358396:CHINAEXTREME RS19410
gene id: 358396:CHINAEXTREME_RS19410
uniprot id: A0A1P8LWH8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

358396:CHINAEXTREME RS08910
gene id: 358396:CHINAEXTREME_RS08910
uniprot id: M0L6D4
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

358396:CHINAEXTREME RS08780
gene id: 358396:CHINAEXTREME_RS08780
uniprot id: M0L7S0
names: Similarity
messages: Belongs to the UPF0284 family.

358396:CHINAEXTREME RS00565
gene id: 358396:CHINAEXTREME_RS00565
uniprot id: M0L1F4
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

358396:CHINAEXTREME RS13850
gene id: 358396:CHINAEXTREME_RS13850
uniprot id: M0LJV9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit.

358396:CHINAEXTREME RS19245
gene id: 358396:CHINAEXTREME_RS19245
uniprot id: M0LSE7
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

358396:CHINAEXTREME RS18860
gene id: 358396:CHINAEXTREME_RS18860
uniprot id: M0LUS4
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.

358396:CHINAEXTREME RS02210
gene id: 358396:CHINAEXTREME_RS02210
uniprot id: M0LI23
names: Similarity
messages: Belongs to the Ahb/Nir family.

358396:CHINAEXTREME RS20710
gene id: 358396:CHINAEXTREME_RS20710
uniprot id: M0L9B4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated exonuclease Cas4 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).
messages: Mg(2+) or Mn(2+) required for ssDNA cleavage activity.

358396:CHINAEXTREME RS01155
gene id: 358396:CHINAEXTREME_RS01155
uniprot id: M0LDY5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

358396:CHINAEXTREME RS10745
gene id: 358396:CHINAEXTREME_RS10745
uniprot id: M0L702
names: Similarity
messages: Belongs to the peptidase S8 family.

358396:CHINAEXTREME RS07945
gene id: 358396:CHINAEXTREME_RS07945
uniprot id: M0LVF9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PdxS/SNZ family.
messages: Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
messages: In the presence of PdxT, forms a dodecamer of heterodimers.

358396:CHINAEXTREME RS14040
gene id: 358396:CHINAEXTREME_RS14040
uniprot id: A0A1P8LSR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

358396:CHINAEXTREME RS01845
gene id: 358396:CHINAEXTREME_RS01845
uniprot id: M0LJF0
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

358396:CHINAEXTREME RS07185
gene id: 358396:CHINAEXTREME_RS07185
uniprot id: M0LY74
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

358396:CHINAEXTREME RS10470
gene id: 358396:CHINAEXTREME_RS10470
uniprot id: M0L3P8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

358396:CHINAEXTREME RS09115
gene id: 358396:CHINAEXTREME_RS09115
uniprot id: M0L6H7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: The complex is composed of two ATP-binding proteins (UgpC), two transmembrane proteins (UgpA and UgpE) and a solute-binding protein (UgpB).

358396:CHINAEXTREME RS13960
gene id: 358396:CHINAEXTREME_RS13960
uniprot id: M0LFI6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCH family.
messages: Catalyzes the hydrolysis of methenyl-H(4)MPT(+) to 5-formyl-H(4)MPT.
messages: Cytoplasm

358396:CHINAEXTREME RS03885
gene id: 358396:CHINAEXTREME_RS03885
uniprot id: M0LRJ4
names: Cofactor
names: Function
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.
messages: Binds 1 zinc ion.
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

358396:CHINAEXTREME RS08640
gene id: 358396:CHINAEXTREME_RS08640
uniprot id: M0LBF1
names: Subcellular Location Annotation
messages: Membrane

358396:CHINAEXTREME RS03910
gene id: 358396:CHINAEXTREME_RS03910
uniprot id: M0LRJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P(II) protein family.
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Membrane

358396:CHINAEXTREME RS19125
gene id: 358396:CHINAEXTREME_RS19125
uniprot id: M0LR61
names: Subcellular Location Annotation
messages: Membrane

358396:CHINAEXTREME RS04220
gene id: 358396:CHINAEXTREME_RS04220
uniprot id: M0LMF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

358396:CHINAEXTREME RS05190
gene id: 358396:CHINAEXTREME_RS05190
uniprot id: M0LKI7
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L-homocysteine, respectively. Is also able to deaminate adenosine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

358396:CHINAEXTREME RS17485
gene id: 358396:CHINAEXTREME_RS17485
uniprot id: M0LGN1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic/archaeal RNase P protein component 4 family.
messages: Binds 1 zinc ion per subunit.
messages: Consists of a catalytic RNA component and at least 4-5 protein subunits.
messages: Cytoplasm
messages: Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.

358396:CHINAEXTREME RS11200
gene id: 358396:CHINAEXTREME_RS11200
uniprot id: M0L2X8
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

358396:CHINAEXTREME RS17505
gene id: 358396:CHINAEXTREME_RS17505
uniprot id: M0LEP5
names: Subcellular Location Annotation
messages: Membrane

358396:CHINAEXTREME RS08535
gene id: 358396:CHINAEXTREME_RS08535
uniprot id: M0LW98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal/bacterial/fungal opsin family.
messages: Membrane

358396:CHINAEXTREME RS15395
gene id: 358396:CHINAEXTREME_RS15395
uniprot id: M0LC96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

358396:CHINAEXTREME RS13695
gene id: 358396:CHINAEXTREME_RS13695
uniprot id: M0LIK4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

358396:CHINAEXTREME RS13215
gene id: 358396:CHINAEXTREME_RS13215
uniprot id: M0LG92
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

358396:CHINAEXTREME RS04305
gene id: 358396:CHINAEXTREME_RS04305
uniprot id: M0LRS7
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

358396:CHINAEXTREME RS16890
gene id: 358396:CHINAEXTREME_RS16890
uniprot id: M0LNU6
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

358396:CHINAEXTREME RS16080
gene id: 358396:CHINAEXTREME_RS16080
uniprot id: M0LB19
names: Similarity
names: Subunit
messages: Belongs to the methylaspartate ammonia-lyase family.
messages: Homodimer.

358396:CHINAEXTREME RS03265
gene id: 358396:CHINAEXTREME_RS03265
uniprot id: M0LMU9
names: Subcellular Location Annotation
messages: Membrane

358396:CHINAEXTREME RS15175
gene id: 358396:CHINAEXTREME_RS15175
uniprot id: M0LFS5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

358396:CHINAEXTREME RS07370
gene id: 358396:CHINAEXTREME_RS07370
uniprot id: M0LV53
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

358396:CHINAEXTREME RS00950
gene id: 358396:CHINAEXTREME_RS00950
uniprot id: M0LFD6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

358396:CHINAEXTREME RS18990
gene id: 358396:CHINAEXTREME_RS18990
uniprot id: M0LUQ5
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.

358396:CHINAEXTREME RS00520
gene id: 358396:CHINAEXTREME_RS00520
uniprot id: M0L5X4
names: Similarity
messages: Belongs to the formate--tetrahydrofolate ligase family.

358396:CHINAEXTREME RS12415
gene id: 358396:CHINAEXTREME_RS12415
uniprot id: M0LM08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Membrane

358396:CHINAEXTREME RS11120
gene id: 358396:CHINAEXTREME_RS11120
uniprot id: M0L2Z9
names: Subcellular Location Annotation
messages: Nucleus

358396:CHINAEXTREME RS20135
gene id: 358396:CHINAEXTREME_RS20135
uniprot id: M0LRZ6
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

358396:CHINAEXTREME RS08120
gene id: 358396:CHINAEXTREME_RS08120
uniprot id: M0LVC6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP). It is probably the precursor of glycosyl carrier lipids.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

358396:CHINAEXTREME RS02415
gene id: 358396:CHINAEXTREME_RS02415
uniprot id: M0LG24
names: Subcellular Location Annotation
messages: Membrane

358396:CHINAEXTREME RS12640
gene id: 358396:CHINAEXTREME_RS12640
uniprot id: M0LM48
names: Similarity
messages: Belongs to the UPF0212 family.

358396:CHINAEXTREME RS03375
gene id: 358396:CHINAEXTREME_RS03375
uniprot id: M0LP69
names: Similarity
messages: Belongs to the TCP-1 chaperonin family.

358396:CHINAEXTREME RS15150
gene id: 358396:CHINAEXTREME_RS15150
uniprot id: M0LFS1
names: Subcellular Location Annotation
messages: Membrane

358396:CHINAEXTREME RS12100
gene id: 358396:CHINAEXTREME_RS12100
uniprot id: M0LI98
names: Subcellular Location Annotation
messages: Membrane

358396:CHINAEXTREME RS10595
gene id: 358396:CHINAEXTREME_RS10595
uniprot id: M0L3S5
names: Subcellular Location Annotation
messages: Membrane

358396:CHINAEXTREME RS02400
gene id: 358396:CHINAEXTREME_RS02400
uniprot id: M0LEQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC41A transporter family.
messages: Membrane

358396:CHINAEXTREME RS07430
gene id: 358396:CHINAEXTREME_RS07430
uniprot id: M0LU99
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

358396:CHINAEXTREME RS12400
gene id: 358396:CHINAEXTREME_RS12400
uniprot id: M0LHG3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

358396:CHINAEXTREME RS05545
gene id: 358396:CHINAEXTREME_RS05545
uniprot id: M0LMT7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

358396:CHINAEXTREME RS19130
gene id: 358396:CHINAEXTREME_RS19130
uniprot id: M0LRG7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

358396:CHINAEXTREME RS00960
gene id: 358396:CHINAEXTREME_RS00960
uniprot id: M0LDZ8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Involved in protein export.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the protein translocation apparatus. Forms a complex with SecF.

358396:CHINAEXTREME RS15615
gene id: 358396:CHINAEXTREME_RS15615
uniprot id: M0LCC1
names: Subcellular Location Annotation
messages: Membrane

358396:CHINAEXTREME RS15260
gene id: 358396:CHINAEXTREME_RS15260
uniprot id: M0LCL8
names: Function
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 1 subfamily.
messages: Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 2-succinylbenzoate (OSB).

358396:CHINAEXTREME RS11385
gene id: 358396:CHINAEXTREME_RS11385
uniprot id: M0L313
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

358396:CHINAEXTREME RS14370
gene id: 358396:CHINAEXTREME_RS14370
uniprot id: M0L0Y9
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

358396:CHINAEXTREME RS09735
gene id: 358396:CHINAEXTREME_RS09735
uniprot id: M0L662
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL37 family.
messages: Binds 1 zinc ion per subunit.
messages: Binds to the 23S rRNA.
messages: Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.

358396:CHINAEXTREME RS11055
gene id: 358396:CHINAEXTREME_RS11055
uniprot id: M0L623
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

358396:CHINAEXTREME RS14850
gene id: 358396:CHINAEXTREME_RS14850
uniprot id: M0LAB5
names: Subcellular Location Annotation
messages: Membrane

358396:CHINAEXTREME RS13595
gene id: 358396:CHINAEXTREME_RS13595
uniprot id: M0LII5
names: Similarity
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.

358396:CHINAEXTREME RS03320
gene id: 358396:CHINAEXTREME_RS03320
uniprot id: M0LP56
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

358396:CHINAEXTREME RS13855
gene id: 358396:CHINAEXTREME_RS13855
uniprot id: M0LFG4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles.
messages: Part of the 30S ribosomal subunit.

358396:CHINAEXTREME RS05555
gene id: 358396:CHINAEXTREME_RS05555
uniprot id: M0LJS2
names: Subcellular Location Annotation
messages: Membrane

358396:CHINAEXTREME RS02675
gene id: 358396:CHINAEXTREME_RS02675
uniprot id: M0LIX8
names: Similarity
messages: Belongs to the thioesterase PaaI family.

358396:CHINAEXTREME RS19165
gene id: 358396:CHINAEXTREME_RS19165
uniprot id: M0LUM5
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: In the C-terminal section; belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

358396:CHINAEXTREME RS01590
gene id: 358396:CHINAEXTREME_RS01590
uniprot id: M0LF09
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

358396:CHINAEXTREME RS03810
gene id: 358396:CHINAEXTREME_RS03810
uniprot id: M0LQD3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM5/TYW2 family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: S-adenosyl-L-methionine-dependent transferase that acts as a component of the wyosine derivatives biosynthesis pathway. Catalyzes the transfer of the alpha-amino-alpha-carboxypropyl (acp) group from S-adenosyl-L-methionine to 4-demethylwyosine (imG-14), forming 7-aminocarboxypropyl-demethylwyosine (wybutosine-86) at position 37 of tRNA(Phe).

358396:CHINAEXTREME RS11350
gene id: 358396:CHINAEXTREME_RS11350
uniprot id: M0L340
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TmcA family.
messages: Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: nucleolus

358396:CHINAEXTREME RS18060
gene id: 358396:CHINAEXTREME_RS18060
uniprot id: M0LI64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Membrane

358396:CHINAEXTREME RS04685
gene id: 358396:CHINAEXTREME_RS04685
uniprot id: M0LMX3
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

358396:CHINAEXTREME RS20775
gene id: 358396:CHINAEXTREME_RS20775
uniprot id: M0LCB7
names: Subcellular Location Annotation
messages: Membrane

358396:CHINAEXTREME RS18050
gene id: 358396:CHINAEXTREME_RS18050
uniprot id: M0LEZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane

358396:CHINAEXTREME RS02670
gene id: 358396:CHINAEXTREME_RS02670
uniprot id: M0LEI4
names: Similarity
messages: Belongs to the cytochrome P450 family.

358396:CHINAEXTREME RS01280
gene id: 358396:CHINAEXTREME_RS01280
uniprot id: M0LDT1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DtdA deacylase family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: D-aminoacyl-tRNA deacylase with broad substrate specificity. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo.
messages: Monomer.

358396:CHINAEXTREME RS10645
gene id: 358396:CHINAEXTREME_RS10645
uniprot id: M0L8F0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

358396:CHINAEXTREME RS06800
gene id: 358396:CHINAEXTREME_RS06800
uniprot id: M0LU86
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL40 family.

358396:CHINAEXTREME RS11125
gene id: 358396:CHINAEXTREME_RS11125
uniprot id: M0L2W4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic-type primase small subunit family.
messages: Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair.
messages: Heterodimer of a small subunit (PriS) and a large subunit (PriL).
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

358396:CHINAEXTREME RS16035
gene id: 358396:CHINAEXTREME_RS16035
uniprot id: M0LE89
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

358396:CHINAEXTREME RS07765
gene id: 358396:CHINAEXTREME_RS07765
uniprot id: M0LXW3
names: Similarity
messages: In the C-terminal section; belongs to the complex I 49 kDa subunit family.

358396:CHINAEXTREME RS15965
gene id: 358396:CHINAEXTREME_RS15965
uniprot id: M0LE74
names: Similarity
messages: Belongs to the UPF0212 family.

358396:CHINAEXTREME RS15490
gene id: 358396:CHINAEXTREME_RS15490
uniprot id: M0LC94
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. HutI family.
messages: Binds 1 zinc or iron ion per subunit.
messages: Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate. It is the third step in the universal histidine degradation pathway.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

358396:CHINAEXTREME RS13470
gene id: 358396:CHINAEXTREME_RS13470
uniprot id: M0LG62
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

358396:CHINAEXTREME RS15715
gene id: 358396:CHINAEXTREME_RS15715
uniprot id: M0LBJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

358396:CHINAEXTREME RS12540
gene id: 358396:CHINAEXTREME_RS12540
uniprot id: M0LHT1
names: Subcellular Location Annotation
messages: Membrane

358396:CHINAEXTREME RS10735
gene id: 358396:CHINAEXTREME_RS10735
uniprot id: M0L3R1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

358396:CHINAEXTREME RS10895
gene id: 358396:CHINAEXTREME_RS10895
uniprot id: M0L458
names: Function
names: Similarity
names: Subunit
messages: Belongs to the kynureninase family.
messages: Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
messages: Homodimer.

358396:CHINAEXTREME RS20130
gene id: 358396:CHINAEXTREME_RS20130
uniprot id: M0LTY9
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

358396:CHINAEXTREME RS08280
gene id: 358396:CHINAEXTREME_RS08280
uniprot id: M0LWF4
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

358396:CHINAEXTREME RS03255
gene id: 358396:CHINAEXTREME_RS03255
uniprot id: M0LS36
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

358396:CHINAEXTREME RS07835
gene id: 358396:CHINAEXTREME_RS07835
uniprot id: M0LTZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

358396:CHINAEXTREME RS14800
gene id: 358396:CHINAEXTREME_RS14800
uniprot id: M0LAC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

358396:CHINAEXTREME RS01755
gene id: 358396:CHINAEXTREME_RS01755
uniprot id: M0LEX7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase archaeal type 2 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).

358396:CHINAEXTREME RS09995
gene id: 358396:CHINAEXTREME_RS09995
uniprot id: M0L4Q4
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL21 family.

358396:CHINAEXTREME RS04995
gene id: 358396:CHINAEXTREME_RS04995
uniprot id: M0LK72
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

358396:CHINAEXTREME RS09870
gene id: 358396:CHINAEXTREME_RS09870
uniprot id: M0L9M8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 3 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

358396:CHINAEXTREME RS05050
gene id: 358396:CHINAEXTREME_RS05050
uniprot id: M0LLQ6
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL39 family.

358396:CHINAEXTREME RS01085
gene id: 358396:CHINAEXTREME_RS01085
uniprot id: M0LIG0
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

358396:CHINAEXTREME RS03275
gene id: 358396:CHINAEXTREME_RS03275
uniprot id: M0LR01
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the inorganic carbon transporter (TC 9.A.2) DabA family.
messages: Cell membrane
messages: Forms a complex with DabB.
messages: Part of an energy-coupled inorganic carbon pump.

358396:CHINAEXTREME RS19975
gene id: 358396:CHINAEXTREME_RS19975
uniprot id: M0LUZ2
names: Subcellular Location Annotation
messages: Cytoplasm

358396:CHINAEXTREME RS08865
gene id: 358396:CHINAEXTREME_RS08865
uniprot id: M0L9K8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

358396:CHINAEXTREME RS03580
gene id: 358396:CHINAEXTREME_RS03580
uniprot id: M0LRD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

358396:CHINAEXTREME RS12020
gene id: 358396:CHINAEXTREME_RS12020
uniprot id: M0LMI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm

358396:CHINAEXTREME RS17875
gene id: 358396:CHINAEXTREME_RS17875
uniprot id: M0LI24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamine synthetase family.
messages: Cytoplasm

358396:CHINAEXTREME RS09975
gene id: 358396:CHINAEXTREME_RS09975
uniprot id: M0L6M4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

358396:CHINAEXTREME RS12330
gene id: 358396:CHINAEXTREME_RS12330
uniprot id: M0LJ02
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

358396:CHINAEXTREME RS09445
gene id: 358396:CHINAEXTREME_RS09445
uniprot id: M0L9F7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

358396:CHINAEXTREME RS13680
gene id: 358396:CHINAEXTREME_RS13680
uniprot id: A0A1P8LSJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

358396:CHINAEXTREME RS18385
gene id: 358396:CHINAEXTREME_RS18385
uniprot id: M0LR81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

358396:CHINAEXTREME RS08755
gene id: 358396:CHINAEXTREME_RS08755
uniprot id: M0L7R6
names: Caution
names: Function
names: Similarity
messages: Belongs to the THEP1 NTPase family.
messages: Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. May hydrolyze nucleoside diphosphates with lower efficiency.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

358396:CHINAEXTREME RS03640
gene id: 358396:CHINAEXTREME_RS03640
uniprot id: M0LM30
names: Function
names: Similarity
messages: Belongs to the CDC6/cdc18 family.
messages: Involved in regulation of DNA replication.

358396:CHINAEXTREME RS15970
gene id: 358396:CHINAEXTREME_RS15970
uniprot id: M0LAX9
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
messages: Cytoplasm
messages: The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped at one or both ends by the proteasome regulatory ATPase, PAN.
messages: The formation of the proteasomal ATPase PAN-20S proteasome complex, via the docking of the C-termini of PAN into the intersubunit pockets in the alpha-rings, triggers opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity.

358396:CHINAEXTREME RS09070
gene id: 358396:CHINAEXTREME_RS09070
uniprot id: M0L7X1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Composed of a catalytic GlpA/B dimer and of membrane bound GlpC.
messages: Membrane

358396:CHINAEXTREME RS12270
gene id: 358396:CHINAEXTREME_RS12270
uniprot id: M0LMM8
names: PTM
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

358396:CHINAEXTREME RS08915
gene id: 358396:CHINAEXTREME_RS08915
uniprot id: M0L7U2
names: Similarity
messages: Belongs to the acetolactate synthase small subunit family.

358396:CHINAEXTREME RS14325
gene id: 358396:CHINAEXTREME_RS14325
uniprot id: M0L470
names: Subcellular Location Annotation
messages: Membrane

358396:CHINAEXTREME RS08850
gene id: 358396:CHINAEXTREME_RS08850
uniprot id: M0L6I5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the diphthine synthase family.
messages: Homodimer.
messages: S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the trimethylation of the amino group of the modified target histidine residue in translation elongation factor 2 (EF-2), to form an intermediate called diphthine. The three successive methylation reactions represent the second step of diphthamide biosynthesis.

358396:CHINAEXTREME RS05745
gene id: 358396:CHINAEXTREME_RS05745
uniprot id: M0LMX6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

358396:CHINAEXTREME RS17525
gene id: 358396:CHINAEXTREME_RS17525
uniprot id: M0LDD7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

358396:CHINAEXTREME RS03660
gene id: 358396:CHINAEXTREME_RS03660
uniprot id: M0LMA0
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family. Archaeal Muts2 subfamily.
messages: Has ATPase and non-specific DNA-binding activities.

358396:CHINAEXTREME RS03480
gene id: 358396:CHINAEXTREME_RS03480
uniprot id: M0LQ71
names: Subcellular Location Annotation
messages: Membrane

358396:CHINAEXTREME RS01870
gene id: 358396:CHINAEXTREME_RS01870
uniprot id: M0LJE3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

358396:CHINAEXTREME RS13200
gene id: 358396:CHINAEXTREME_RS13200
uniprot id: M0LHK0
names: Subcellular Location Annotation
messages: Membrane

358396:CHINAEXTREME RS07930
gene id: 358396:CHINAEXTREME_RS07930
uniprot id: M0LZL4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

358396:CHINAEXTREME RS00745
gene id: 358396:CHINAEXTREME_RS00745
uniprot id: A0A1P8LKR2
names: Subcellular Location Annotation
messages: Membrane

358396:CHINAEXTREME RS09930
gene id: 358396:CHINAEXTREME_RS09930
uniprot id: M0L4I3
names: Subcellular Location Annotation
messages: Membrane

358396:CHINAEXTREME RS16665
gene id: 358396:CHINAEXTREME_RS16665
uniprot id: M0LFV7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

358396:CHINAEXTREME RS13140
gene id: 358396:CHINAEXTREME_RS13140
uniprot id: M0LG82
names: Similarity
messages: Belongs to the UPF0145 family.

358396:CHINAEXTREME RS09430
gene id: 358396:CHINAEXTREME_RS09430
uniprot id: M0L4P8
names: Subcellular Location Annotation
messages: Membrane

358396:CHINAEXTREME RS07250
gene id: 358396:CHINAEXTREME_RS07250
uniprot id: M0LU16
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

358396:CHINAEXTREME RS08855
gene id: 358396:CHINAEXTREME_RS08855
uniprot id: M0L6C6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

358396:CHINAEXTREME RS09045
gene id: 358396:CHINAEXTREME_RS09045
uniprot id: M0L6G1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STT3 family.
messages: Membrane

358396:CHINAEXTREME RS13970
gene id: 358396:CHINAEXTREME_RS13970
uniprot id: M0LGV5
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.

358396:CHINAEXTREME RS11080
gene id: 358396:CHINAEXTREME_RS11080
uniprot id: M0L493
names: Similarity
messages: Belongs to the thiolase-like superfamily. HMG-CoA synthase family.

358396:CHINAEXTREME RS04030
gene id: 358396:CHINAEXTREME_RS04030
uniprot id: M0LQH9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

358396:CHINAEXTREME RS12840
gene id: 358396:CHINAEXTREME_RS12840
uniprot id: M0LHB6
names: Function
names: Similarity
messages: Belongs to the adenylate kinase family. AK6 subfamily.
messages: Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates.

358396:CHINAEXTREME RS08310
gene id: 358396:CHINAEXTREME_RS08310
uniprot id: M0LV71
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

358396:CHINAEXTREME RS17495
gene id: 358396:CHINAEXTREME_RS17495
uniprot id: M0LDB1
names: Subcellular Location Annotation
messages: Membrane

358396:CHINAEXTREME RS05825
gene id: 358396:CHINAEXTREME_RS05825
uniprot id: M0LP70
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

358396:CHINAEXTREME RS13835
gene id: 358396:CHINAEXTREME_RS13835
uniprot id: M0LFC9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL19 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

358396:CHINAEXTREME RS09535
gene id: 358396:CHINAEXTREME_RS09535
uniprot id: M0L632
names: Subcellular Location Annotation
messages: Membrane

358396:CHINAEXTREME RS04165
gene id: 358396:CHINAEXTREME_RS04165
uniprot id: M0LMK0
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

358396:CHINAEXTREME RS04035
gene id: 358396:CHINAEXTREME_RS04035
uniprot id: M0LRM4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

358396:CHINAEXTREME RS16430
gene id: 358396:CHINAEXTREME_RS16430
uniprot id: M0LB90
names: Similarity
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.

358396:CHINAEXTREME RS16180
gene id: 358396:CHINAEXTREME_RS16180
uniprot id: M0LB22
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
messages: Cytoplasm
messages: The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped at one or both ends by the proteasome regulatory ATPase, PAN.
messages: The formation of the proteasomal ATPase PAN-20S proteasome complex, via the docking of the C-termini of PAN into the intersubunit pockets in the alpha-rings, triggers opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity.

358396:CHINAEXTREME RS07265
gene id: 358396:CHINAEXTREME_RS07265
uniprot id: M0LXI0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M32 family.
messages: Binds 1 zinc ion per subunit.
messages: Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues.

358396:CHINAEXTREME RS10560
gene id: 358396:CHINAEXTREME_RS10560
uniprot id: M0L6X1
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

358396:CHINAEXTREME RS20280
gene id: 358396:CHINAEXTREME_RS20280
uniprot id: M0LS58
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: S-layer

358396:CHINAEXTREME RS11875
gene id: 358396:CHINAEXTREME_RS11875
uniprot id: M0LC17
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

358396:CHINAEXTREME RS13030
gene id: 358396:CHINAEXTREME_RS13030
uniprot id: M0LHH4
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

358396:CHINAEXTREME RS15405
gene id: 358396:CHINAEXTREME_RS15405
uniprot id: M0LFJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

358396:CHINAEXTREME RS02120
gene id: 358396:CHINAEXTREME_RS02120
uniprot id: M0LEV3
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.

358396:CHINAEXTREME RS05740
gene id: 358396:CHINAEXTREME_RS05740
uniprot id: M0LL60
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 2 subfamily.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

358396:CHINAEXTREME RS02110
gene id: 358396:CHINAEXTREME_RS02110
uniprot id: M0LG73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

358396:CHINAEXTREME RS00590
gene id: 358396:CHINAEXTREME_RS00590
uniprot id: M0L1F0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

358396:CHINAEXTREME RS12655
gene id: 358396:CHINAEXTREME_RS12655
uniprot id: A0A1P8LS25
names: Function
names: Similarity
messages: Belongs to the TFIIB family.
messages: Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB).

358396:CHINAEXTREME RS14970
gene id: 358396:CHINAEXTREME_RS14970
uniprot id: M0L9D1
names: Similarity
messages: Belongs to the manganese catalase family.

358396:CHINAEXTREME RS19650
gene id: 358396:CHINAEXTREME_RS19650
uniprot id: A0A1P8LVP8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

358396:CHINAEXTREME RS09210
gene id: 358396:CHINAEXTREME_RS09210
uniprot id: M0L7R9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-archaeol synthase family.
messages: Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate (DGGGP) and CTP. This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids.
messages: Cell membrane

358396:CHINAEXTREME RS07920
gene id: 358396:CHINAEXTREME_RS07920
uniprot id: A0A1P8LPJ5
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

358396:CHINAEXTREME RS01785
gene id: 358396:CHINAEXTREME_RS01785
uniprot id: M0LEX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal/bacterial/fungal opsin family.
messages: Membrane

358396:CHINAEXTREME RS07230
gene id: 358396:CHINAEXTREME_RS07230
uniprot id: M0LUD0
names: PTM
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

358396:CHINAEXTREME RS10450
gene id: 358396:CHINAEXTREME_RS10450
uniprot id: A0A1P8LQZ4
names: Subcellular Location Annotation
messages: Membrane

358396:CHINAEXTREME RS19155
gene id: 358396:CHINAEXTREME_RS19155
uniprot id: M0LRG2
names: Similarity
messages: Belongs to the glutaredoxin family.

358396:CHINAEXTREME RS16460
gene id: 358396:CHINAEXTREME_RS16460
uniprot id: M0LCJ2
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

358396:CHINAEXTREME RS07355
gene id: 358396:CHINAEXTREME_RS07355
uniprot id: M0LUB4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

358396:CHINAEXTREME RS04310
gene id: 358396:CHINAEXTREME_RS04310
uniprot id: M0LMN0
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

358396:CHINAEXTREME RS16300
gene id: 358396:CHINAEXTREME_RS16300
uniprot id: M0LFN9
names: Similarity
messages: Belongs to the dihydrofolate reductase family.

358396:CHINAEXTREME RS01300
gene id: 358396:CHINAEXTREME_RS01300
uniprot id: M0LDU9
names: Function
messages: Part of a potassium transport system.

358396:CHINAEXTREME RS18810
gene id: 358396:CHINAEXTREME_RS18810
uniprot id: M0LSK4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

358396:CHINAEXTREME RS00305
gene id: 358396:CHINAEXTREME_RS00305
uniprot id: M0L613
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal NMN adenylyltransferase family.
messages: Cytoplasm

358396:CHINAEXTREME RS13055
gene id: 358396:CHINAEXTREME_RS13055
uniprot id: M0LHI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal/bacterial/fungal opsin family.
messages: Membrane

358396:CHINAEXTREME RS16990
gene id: 358396:CHINAEXTREME_RS16990
uniprot id: M0LNS4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PTH2 family.
messages: Cytoplasm
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

358396:CHINAEXTREME RS09410
gene id: 358396:CHINAEXTREME_RS09410
uniprot id: M0L615
names: Cofactor
names: Similarity
messages: Belongs to the ELP3 family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

358396:CHINAEXTREME RS01640
gene id: 358396:CHINAEXTREME_RS01640
uniprot id: A0A1P8LL98
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

358396:CHINAEXTREME RS13430
gene id: 358396:CHINAEXTREME_RS13430
uniprot id: M0LJK4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

358396:CHINAEXTREME RS13350
gene id: 358396:CHINAEXTREME_RS13350
uniprot id: M0LHM2
names: Similarity
messages: Belongs to the AOR/FOR family.

358396:CHINAEXTREME RS09530
gene id: 358396:CHINAEXTREME_RS09530
uniprot id: M0L4R4
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: Probably part of an ABC transporter complex. Responsible for energy coupling to the transport system.

358396:CHINAEXTREME RS15795
gene id: 358396:CHINAEXTREME_RS15795
uniprot id: M0LBL2
names: Subcellular Location Annotation
messages: Membrane

358396:CHINAEXTREME RS09785
gene id: 358396:CHINAEXTREME_RS09785
uniprot id: M0L669
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 2 subfamily.
messages: Binds 3 Mg(2+) cations per subunit. The strongest magnesium site (Mg1) is bound to the beta- and gamma-phosphates of ATP and four water molecules complete its coordination sphere.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

358396:CHINAEXTREME RS20095
gene id: 358396:CHINAEXTREME_RS20095
uniprot id: M0LQW3
names: Subcellular Location Annotation
messages: Membrane

358396:CHINAEXTREME RS11000
gene id: 358396:CHINAEXTREME_RS11000
uniprot id: M0L609
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

358396:CHINAEXTREME RS15365
gene id: 358396:CHINAEXTREME_RS15365
uniprot id: A0A1P8LTF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

358396:CHINAEXTREME RS11495
gene id: 358396:CHINAEXTREME_RS11495
uniprot id: M0L7R5
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

358396:CHINAEXTREME RS03220
gene id: 358396:CHINAEXTREME_RS03220
uniprot id: M0LP35
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

358396:CHINAEXTREME RS01025
gene id: 358396:CHINAEXTREME_RS01025
uniprot id: M0LFC1
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

358396:CHINAEXTREME RS15420
gene id: 358396:CHINAEXTREME_RS15420
uniprot id: M0LCA1
names: Similarity
messages: Belongs to the peptidase S8 family.

358396:CHINAEXTREME RS01460
gene id: 358396:CHINAEXTREME_RS01460
uniprot id: M0LGJ2
names: Similarity
messages: Belongs to the archaeosine synthase type 1 family.

358396:CHINAEXTREME RS04095
gene id: 358396:CHINAEXTREME_RS04095
uniprot id: M0LMC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm

358396:CHINAEXTREME RS15580
gene id: 358396:CHINAEXTREME_RS15580
uniprot id: M0LFM0
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 2 subfamily.
messages: Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

358396:CHINAEXTREME RS10635
gene id: 358396:CHINAEXTREME_RS10635
uniprot id: M0L514
names: Subcellular Location Annotation
messages: Cell membrane

358396:CHINAEXTREME RS19290
gene id: 358396:CHINAEXTREME_RS19290
uniprot id: M0LUK4
names: Function
names: Similarity
messages: Belongs to the CDC6/cdc18 family.
messages: Involved in regulation of DNA replication.

358396:CHINAEXTREME RS13540
gene id: 358396:CHINAEXTREME_RS13540
uniprot id: M0LGF0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Brp/Blh beta-carotene diooxygenase family.
messages: Catalyzes the cleavage of beta-carotene at its central double bond (15,15') to yield two molecules of all-trans-retinal.
messages: Cell membrane

358396:CHINAEXTREME RS09690
gene id: 358396:CHINAEXTREME_RS09690
uniprot id: M0L805
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA2/NAM7 helicase family.
messages: Nucleus

358396:CHINAEXTREME RS16020
gene id: 358396:CHINAEXTREME_RS16020
uniprot id: M0LAZ0
names: Similarity
messages: Belongs to the eIF-2B alpha/beta/delta subunits family.

358396:CHINAEXTREME RS15785
gene id: 358396:CHINAEXTREME_RS15785
uniprot id: M0LG26
names: Subcellular Location Annotation
messages: Membrane

358396:CHINAEXTREME RS07975
gene id: 358396:CHINAEXTREME_RS07975
uniprot id: A0A1P8LPJ6
names: Subcellular Location Annotation
messages: Membrane

358396:CHINAEXTREME RS00105
gene id: 358396:CHINAEXTREME_RS00105
uniprot id: A0A1P8LKE4
names: Similarity
messages: Belongs to the AOR/FOR family.

358396:CHINAEXTREME RS04620
gene id: 358396:CHINAEXTREME_RS04620
uniprot id: M0LQV2
names: Subcellular Location Annotation
messages: Membrane

358396:CHINAEXTREME RS19640
gene id: 358396:CHINAEXTREME_RS19640
uniprot id: M0LQX6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

358396:CHINAEXTREME RS07515
gene id: 358396:CHINAEXTREME_RS07515
uniprot id: M0LXC5
names: Similarity
messages: Belongs to the serine/threonine dehydratase family.

358396:CHINAEXTREME RS01415
gene id: 358396:CHINAEXTREME_RS01415
uniprot id: M0LF48
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

358396:CHINAEXTREME RS12725
gene id: 358396:CHINAEXTREME_RS12725
uniprot id: M0LFT8
names: Similarity
messages: Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.

358396:CHINAEXTREME RS05135
gene id: 358396:CHINAEXTREME_RS05135
uniprot id: M0LPS5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

358396:CHINAEXTREME RS16645
gene id: 358396:CHINAEXTREME_RS16645
uniprot id: M0LBC4
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

358396:CHINAEXTREME RS05000
gene id: 358396:CHINAEXTREME_RS05000
uniprot id: M0LLP7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

358396:CHINAEXTREME RS15165
gene id: 358396:CHINAEXTREME_RS15165
uniprot id: M0LCJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal Rpo11/eukaryotic RPB11/RPC19 RNA polymerase subunit family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

358396:CHINAEXTREME RS19610
gene id: 358396:CHINAEXTREME_RS19610
uniprot id: M0LQX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

358396:CHINAEXTREME RS04355
gene id: 358396:CHINAEXTREME_RS04355
uniprot id: M0LNT0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. Hel308 subfamily.
messages: DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks.
messages: Monomer.

358396:CHINAEXTREME RS04315
gene id: 358396:CHINAEXTREME_RS04315
uniprot id: M0LMH6
names: Function
names: Similarity
messages: Belongs to the archaeal IMP cyclohydrolase family.
messages: Catalyzes the cyclization of 5-formylamidoimidazole-4-carboxamide ribonucleotide to IMP.

358396:CHINAEXTREME RS06795
gene id: 358396:CHINAEXTREME_RS06795
uniprot id: M0LVD8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Aminocarboxypropyltransferase that catalyzes the aminocarboxypropyl transfer on pseudouridine corresponding to position 914 in M.jannaschii 16S rRNA. It constitutes the last step in biosynthesis of the hypermodified N1-methyl-N3-(3-amino-3-carboxypropyl) pseudouridine (m1acp3-Psi).
messages: Belongs to the TDD superfamily. TSR3 family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

358396:CHINAEXTREME RS06715
gene id: 358396:CHINAEXTREME_RS06715
uniprot id: A0A1P8LW23
names: Function
names: Similarity
messages: Belongs to the FAU-1 family.
messages: Probable RNase involved in rRNA stability through maturation and/or degradation of precursor rRNAs. Binds to RNA in loop regions with AU-rich sequences.

358396:CHINAEXTREME RS18020
gene id: 358396:CHINAEXTREME_RS18020
uniprot id: M0LDM5
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

358396:CHINAEXTREME RS13715
gene id: 358396:CHINAEXTREME_RS13715
uniprot id: M0LIL0
names: Subcellular Location Annotation
messages: Membrane

358396:CHINAEXTREME RS00460
gene id: 358396:CHINAEXTREME_RS00460
uniprot id: M0L1G6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CetZ family.
messages: Cytoplasm
messages: Involved in cell shape control.

358396:CHINAEXTREME RS11225
gene id: 358396:CHINAEXTREME_RS11225
uniprot id: M0L318
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

358396:CHINAEXTREME RS00525
gene id: 358396:CHINAEXTREME_RS00525
uniprot id: M0L4L7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

358396:CHINAEXTREME RS16425
gene id: 358396:CHINAEXTREME_RS16425
uniprot id: M0LB74
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

358396:CHINAEXTREME RS12855
gene id: 358396:CHINAEXTREME_RS12855
uniprot id: M0LFW6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

358396:CHINAEXTREME RS01030
gene id: 358396:CHINAEXTREME_RS01030
uniprot id: M0LE15
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Heterodimer composed of a glutamine amidotransferase subunit (A) and a GMP-binding subunit (B).

358396:CHINAEXTREME RS10980
gene id: 358396:CHINAEXTREME_RS10980
uniprot id: M0L7E8
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

358396:CHINAEXTREME RS09800
gene id: 358396:CHINAEXTREME_RS09800
uniprot id: M0L4X9
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. PoK subfamily.
messages: Phosphorylates (R)-pantoate to form (R)-4-phosphopantoate in the CoA biosynthesis pathway.

358396:CHINAEXTREME RS05645
gene id: 358396:CHINAEXTREME_RS05645
uniprot id: M0LMV6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane
messages: Potential transporter for phosphate.

358396:CHINAEXTREME RS10580
gene id: 358396:CHINAEXTREME_RS10580
uniprot id: A0A1P8LQY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the halobacterial S-layer protein family.
messages: Cell membrane
messages: Membrane
messages: S-layer

358396:CHINAEXTREME RS12980
gene id: 358396:CHINAEXTREME_RS12980
uniprot id: M0LHG4
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

358396:CHINAEXTREME RS05635
gene id: 358396:CHINAEXTREME_RS05635
uniprot id: M0LJI8
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

358396:CHINAEXTREME RS18685
gene id: 358396:CHINAEXTREME_RS18685
uniprot id: M0LPZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

358396:CHINAEXTREME RS04265
gene id: 358396:CHINAEXTREME_RS04265
uniprot id: M0LMG6
names: Similarity
messages: Belongs to the threonine aldolase family.

358396:CHINAEXTREME RS04665
gene id: 358396:CHINAEXTREME_RS04665
uniprot id: M0LPP0
names: Subcellular Location Annotation
messages: Membrane

358396:CHINAEXTREME RS15815
gene id: 358396:CHINAEXTREME_RS15815
uniprot id: M0LBK5
names: Subcellular Location Annotation
messages: Membrane

358396:CHINAEXTREME RS00865
gene id: 358396:CHINAEXTREME_RS00865
uniprot id: M0LIK2
names: Function
names: Similarity
messages: Belongs to the archaeal-type DHQ synthase family.
messages: Catalyzes the oxidative deamination and cyclization of 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonic acid (ADH) to yield 3-dehydroquinate (DHQ), which is fed into the canonical shikimic pathway of aromatic amino acid biosynthesis.

358396:CHINAEXTREME RS19285
gene id: 358396:CHINAEXTREME_RS19285
uniprot id: M0LVD5
names: Similarity
names: Subunit
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Homohexamer.

358396:CHINAEXTREME RS07610
gene id: 358396:CHINAEXTREME_RS07610
uniprot id: M0LXZ2
names: Subcellular Location Annotation
messages: Membrane

358396:CHINAEXTREME RS18405
gene id: 358396:CHINAEXTREME_RS18405
uniprot id: M0LR78
names: Subcellular Location Annotation
messages: Membrane

358396:CHINAEXTREME RS03750
gene id: 358396:CHINAEXTREME_RS03750
uniprot id: M0LM50
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
messages: Cytoplasm
messages: Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.