357804:PING RS16420
gene id: 357804:PING_RS16420
uniprot id: A1SZG2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.

357804:PING RS06600
gene id: 357804:PING_RS06600
uniprot id: A1SUB3
names: Function
names: Subcellular Location Annotation
messages: May play a structural or regulatory role in gas vesicle synthesis.
messages: Vesicle
messages: gas vesicle

357804:PING RS05845
gene id: 357804:PING_RS05845
uniprot id: A1STX6
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

357804:PING RS19415
gene id: 357804:PING_RS19415
uniprot id: A1SUN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpxP/Spy family.
messages: Periplasm

357804:PING RS16070
gene id: 357804:PING_RS16070
uniprot id: A1SZA5
names: Function
names: Similarity
messages: Belongs to the Dus family. DusA subfamily.
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs.

357804:PING RS10270
gene id: 357804:PING_RS10270
uniprot id: A1SW82
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

357804:PING RS16310
gene id: 357804:PING_RS16310
uniprot id: A1SZE1
names: Activity Regulation
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.

357804:PING RS06120
gene id: 357804:PING_RS06120
uniprot id: A1SU30
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

357804:PING RS04590
gene id: 357804:PING_RS04590
uniprot id: A1ST99
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetyltransferase family. ArgA subfamily.
messages: Cytoplasm
messages: In bacteria which possess the bifunctional enzyme ornithine acetyltransferase/N-acetylglutamate synthase (ArgJ), ArgA fulfills an anaplerotic role.

357804:PING RS17340
gene id: 357804:PING_RS17340
uniprot id: A1SZY2
names: Function
names: Similarity
names: Subunit
messages: Catalyzes the ADP transfer from ATP to D-glycero-beta-D-manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.
messages: Catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate at the C-1 position to selectively form D-glycero-beta-D-manno-heptose-1,7-bisphosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the cytidylyltransferase family.
messages: In the N-terminal section; belongs to the carbohydrate kinase PfkB family.

357804:PING RS07090
gene id: 357804:PING_RS07090
uniprot id: A1SUJ8
names: Subcellular Location Annotation
messages: Membrane

357804:PING RS01715
gene id: 357804:PING_RS01715
uniprot id: A1SRR9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

357804:PING RS04160
gene id: 357804:PING_RS04160
uniprot id: A1ST19
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

357804:PING RS15870
gene id: 357804:PING_RS15870
uniprot id: A1SZ70
names: Similarity
messages: Belongs to the bacterial PQQ dehydrogenase family.

357804:PING RS18210
gene id: 357804:PING_RS18210
uniprot id: A1T0E3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

357804:PING RS14895
gene id: 357804:PING_RS14895
uniprot id: A1SYM9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptA family.
messages: Component of the lipopolysaccharide transport and assembly complex.
messages: Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm.
messages: Periplasm

357804:PING RS00595
gene id: 357804:PING_RS00595
uniprot id: A1SR64
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP L family.
messages: Cell inner membrane
messages: Inner membrane component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.
messages: Membrane

357804:PING RS15505
gene id: 357804:PING_RS15505
uniprot id: A1SYZ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

357804:PING RS04595
gene id: 357804:PING_RS04595
uniprot id: A1STA0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Cytoplasm
messages: Homodimer.

357804:PING RS17775
gene id: 357804:PING_RS17775
uniprot id: A1T057
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

357804:PING RS01095
gene id: 357804:PING_RS01095
uniprot id: A1SRF9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Monomer.

357804:PING RS05055
gene id: 357804:PING_RS05055
uniprot id: A1STH7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

357804:PING RS18075
gene id: 357804:PING_RS18075
uniprot id: A1SXW9
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

357804:PING RS05405
gene id: 357804:PING_RS05405
uniprot id: A1STP2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

357804:PING RS02825
gene id: 357804:PING_RS02825
uniprot id: A1SSC7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

357804:PING RS03750
gene id: 357804:PING_RS03750
uniprot id: A1SSV3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RuvC family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.

357804:PING RS15630
gene id: 357804:PING_RS15630
uniprot id: A1SZ21
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.

357804:PING RS15140
gene id: 357804:PING_RS15140
uniprot id: A1SYS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

357804:PING RS18860
gene id: 357804:PING_RS18860
uniprot id: A1T0S5
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MdcC family.
messages: Covalently binds the prosthetic group of malonate decarboxylase.
messages: Cytoplasm
messages: Subunit of malonate decarboxylase, it is an acyl carrier protein to which acetyl and malonyl thioester residues are bound via a 2'-(5''-phosphoribosyl)-3'-dephospho-CoA prosthetic group and turn over during the catalytic mechanism.

357804:PING RS18110
gene id: 357804:PING_RS18110
uniprot id: A1T0C3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

357804:PING RS11315
gene id: 357804:PING_RS11315
uniprot id: A1SWS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

357804:PING RS08630
gene id: 357804:PING_RS08630
uniprot id: A1SVC3
names: Similarity
messages: Belongs to the iron-containing alcohol dehydrogenase family.

357804:PING RS09070
gene id: 357804:PING_RS09070
uniprot id: A1SVK3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.
messages: Membrane

357804:PING RS02855
gene id: 357804:PING_RS02855
uniprot id: A1SSD2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

357804:PING RS15705
gene id: 357804:PING_RS15705
uniprot id: A1SZ36
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.
messages: Membrane

357804:PING RS07415
gene id: 357804:PING_RS07415
uniprot id: A1SUQ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

357804:PING RS14015
gene id: 357804:PING_RS14015
uniprot id: A1SY60
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COX11/CtaG family.
messages: Cell inner membrane
messages: Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I.

357804:PING RS19220
gene id: 357804:PING_RS19220
uniprot id: A1T0Y9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

357804:PING RS05665
gene id: 357804:PING_RS05665
uniprot id: A1STU2
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

357804:PING RS18760
gene id: 357804:PING_RS18760
uniprot id: A1T0Q6
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family.

357804:PING RS02370
gene id: 357804:PING_RS02370
uniprot id: A1SS44
names: Subcellular Location Annotation
messages: Membrane

357804:PING RS00715
gene id: 357804:PING_RS00715
uniprot id: A1SR85
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

357804:PING RS03095
gene id: 357804:PING_RS03095
uniprot id: A1SSH3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DksA family.
messages: Cytoplasm
messages: Interacts directly with the RNA polymerase.
messages: Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression.

357804:PING RS16060
gene id: 357804:PING_RS16060
uniprot id: A1SZA3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

357804:PING RS17805
gene id: 357804:PING_RS17805
uniprot id: A1T063
names: Similarity
messages: Belongs to the RutC family.

357804:PING RS11440
gene id: 357804:PING_RS11440
uniprot id: A1SWU5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged L-seryl-tRNA(Thr).
messages: Cytoplasm
messages: Homodimer.

357804:PING RS18630
gene id: 357804:PING_RS18630
uniprot id: A1T0M9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell inner membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

357804:PING RS04970
gene id: 357804:PING_RS04970
uniprot id: A1STH1
names: Similarity
messages: Belongs to the UPF0276 family.

357804:PING RS01550
gene id: 357804:PING_RS01550
uniprot id: A1SRN7
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

357804:PING RS19150
gene id: 357804:PING_RS19150
uniprot id: A1T0X6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

357804:PING RS18265
gene id: 357804:PING_RS18265
uniprot id: A1T0F4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

357804:PING RS08075
gene id: 357804:PING_RS08075
uniprot id: A1SV36
names: Function
names: Similarity
messages: In the C-terminal section; belongs to the aldehyde dehydrogenase family.
messages: In the N-terminal section; belongs to the proline dehydrogenase family.
messages: Oxidizes proline to glutamate for use as a carbon and nitrogen source.

357804:PING RS17105
gene id: 357804:PING_RS17105
uniprot id: A1SZT7
names: Similarity
messages: In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
messages: In the N-terminal section; belongs to the aldehyde dehydrogenase family.

357804:PING RS12415
gene id: 357804:PING_RS12415
uniprot id: A1SXC2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

357804:PING RS17420
gene id: 357804:PING_RS17420
uniprot id: A1SZZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OadG family.
messages: Catalyzes the decarboxylation of oxaloacetate coupled to Na(+) translocation.
messages: Cell membrane
messages: Heterotrimer of an alpha, a beta and a gamma subunit.
messages: Membrane

357804:PING RS08545
gene id: 357804:PING_RS08545
uniprot id: A1SVA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Membrane

357804:PING RS11770
gene id: 357804:PING_RS11770
uniprot id: A1SX09
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RlmKL family.
messages: Cytoplasm
messages: Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA.

357804:PING RS17995
gene id: 357804:PING_RS17995
uniprot id: A1T0A0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0761 family.
messages: Cell inner membrane

357804:PING RS11365
gene id: 357804:PING_RS11365
uniprot id: A1SWT0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

357804:PING RS14235
gene id: 357804:PING_RS14235
uniprot id: A1SYA2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

357804:PING RS17970
gene id: 357804:PING_RS17970
uniprot id: A1T095
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

357804:PING RS18035
gene id: 357804:PING_RS18035
uniprot id: A1T0A8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Catalyzes the sodium-dependent uptake of extracellular L-proline.
messages: Cell inner membrane
messages: Membrane

357804:PING RS07700
gene id: 357804:PING_RS07700
uniprot id: A1SUW3
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

357804:PING RS10340
gene id: 357804:PING_RS10340
uniprot id: A1SW94
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. PdxB subfamily.
messages: Catalyzes the oxidation of erythronate-4-phosphate to 3-hydroxy-2-oxo-4-phosphonooxybutanoate.
messages: Cytoplasm
messages: Homodimer.

357804:PING RS09520
gene id: 357804:PING_RS09520
uniprot id: A1SVT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

357804:PING RS15280
gene id: 357804:PING_RS15280
uniprot id: A1SYV3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

357804:PING RS16875
gene id: 357804:PING_RS16875
uniprot id: A1SZP6
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

357804:PING RS07810
gene id: 357804:PING_RS07810
uniprot id: A1SUY4
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

357804:PING RS17830
gene id: 357804:PING_RS17830
uniprot id: A1T068
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

357804:PING RS18105
gene id: 357804:PING_RS18105
uniprot id: A1T0C2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell inner membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

357804:PING RS10605
gene id: 357804:PING_RS10605
uniprot id: A1SWD8
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

357804:PING RS14940
gene id: 357804:PING_RS14940
uniprot id: A1SYN8
names: Cofactor
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.

357804:PING RS17110
gene id: 357804:PING_RS17110
uniprot id: A1SZT8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase D family. Cardiolipin synthase subfamily. ClsA sub-subfamily.
messages: Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
messages: Cell inner membrane
messages: Membrane

357804:PING RS03885
gene id: 357804:PING_RS03885
uniprot id: A1SSX4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.
messages: Binds 3 [4Fe-4S] clusters.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

357804:PING RS09540
gene id: 357804:PING_RS09540
uniprot id: A1SVU2
names: Cofactor
messages: Binds 3 heme c groups covalently per subunit.

357804:PING RS17890
gene id: 357804:PING_RS17890
uniprot id: A1T079
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

357804:PING RS07960
gene id: 357804:PING_RS07960
uniprot id: A1SV13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

357804:PING RS06735
gene id: 357804:PING_RS06735
uniprot id: A1SUD8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

357804:PING RS18240
gene id: 357804:PING_RS18240
uniprot id: A1T0E9
names: Function
names: Similarity
messages: Belongs to the esterase D family.
messages: Serine hydrolase involved in the detoxification of formaldehyde.

357804:PING RS17450
gene id: 357804:PING_RS17450
uniprot id: A1T000
names: Similarity
messages: Belongs to the aspartokinase family.

357804:PING RS15710
gene id: 357804:PING_RS15710
uniprot id: A1SZ37
names: Similarity
messages: Belongs to the hyi family.

357804:PING RS18445
gene id: 357804:PING_RS18445
uniprot id: A1T0J1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

357804:PING RS18150
gene id: 357804:PING_RS18150
uniprot id: A1T0D1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

357804:PING RS18180
gene id: 357804:PING_RS18180
uniprot id: A1T0D7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity).

357804:PING RS15490
gene id: 357804:PING_RS15490
uniprot id: A1SYZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

357804:PING RS14740
gene id: 357804:PING_RS14740
uniprot id: A1SYJ9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

357804:PING RS15255
gene id: 357804:PING_RS15255
uniprot id: A1SYU8
names: Subcellular Location Annotation
messages: Cytoplasm

357804:PING RS01380
gene id: 357804:PING_RS01380
uniprot id: A1SRK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S33 family.
messages: Cytoplasm

357804:PING RS11465
gene id: 357804:PING_RS11465
uniprot id: A1SWV0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Cytoplasm
messages: Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA.

357804:PING RS05770
gene id: 357804:PING_RS05770
uniprot id: A1STW3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

357804:PING RS00525
gene id: 357804:PING_RS00525
uniprot id: A1SR50
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

357804:PING RS03875
gene id: 357804:PING_RS03875
uniprot id: A1SSX2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

357804:PING RS03950
gene id: 357804:PING_RS03950
uniprot id: A1SSY7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

357804:PING RS02620
gene id: 357804:PING_RS02620
uniprot id: A1SS88
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Monomer.
messages: Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.

357804:PING RS12945
gene id: 357804:PING_RS12945
uniprot id: A1SXL9
names: Similarity
messages: Belongs to the iron-containing alcohol dehydrogenase family.

357804:PING RS12910
gene id: 357804:PING_RS12910
uniprot id: A1SXL2
names: Similarity
messages: Belongs to the aldose epimerase family.

357804:PING RS04830
gene id: 357804:PING_RS04830
uniprot id: A1STE6
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

357804:PING RS03795
gene id: 357804:PING_RS03795
uniprot id: A1SSW2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbD/TolR family.
messages: Cell inner membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

357804:PING RS07295
gene id: 357804:PING_RS07295
uniprot id: A1SUN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

357804:PING RS01615
gene id: 357804:PING_RS01615
uniprot id: A1SRQ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.

357804:PING RS00465
gene id: 357804:PING_RS00465
uniprot id: A1SR38
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

357804:PING RS08100
gene id: 357804:PING_RS08100
uniprot id: A1SV40
names: Similarity
messages: Belongs to the DNA photolyase class-1 family.
messages: Belongs to the DNA photolyase family.

357804:PING RS04735
gene id: 357804:PING_RS04735
uniprot id: A1STC7
names: Subcellular Location Annotation
messages: Membrane

357804:PING RS04665
gene id: 357804:PING_RS04665
uniprot id: A1STB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

357804:PING RS00290
gene id: 357804:PING_RS00290
uniprot id: A1SR08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

357804:PING RS08715
gene id: 357804:PING_RS08715
uniprot id: A1SVE1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LolA family.
messages: Monomer.
messages: Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).
messages: Periplasm

357804:PING RS17930
gene id: 357804:PING_RS17930
uniprot id: A1T087
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family.
messages: Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
messages: Cell inner membrane

357804:PING RS17365
gene id: 357804:PING_RS17365
uniprot id: A1SZY7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

357804:PING RS06660
gene id: 357804:PING_RS06660
uniprot id: A1SUC5
names: Function
names: Subcellular Location Annotation
messages: May play a structural or regulatory role in gas vesicle synthesis.
messages: Vesicle
messages: gas vesicle

357804:PING RS16515
gene id: 357804:PING_RS16515
uniprot id: A1SZH6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.

357804:PING RS17270
gene id: 357804:PING_RS17270
uniprot id: A1SZW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

357804:PING RS05740
gene id: 357804:PING_RS05740
uniprot id: A1STV7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YceF subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes 7-methyl-GTP (m(7)GTP). May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

357804:PING RS18185
gene id: 357804:PING_RS18185
uniprot id: A1T0D8
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

357804:PING RS12630
gene id: 357804:PING_RS12630
uniprot id: A1SXG5
names: Similarity
messages: Belongs to the glutaredoxin family. Monothiol subfamily.

357804:PING RS15535
gene id: 357804:PING_RS15535
uniprot id: A1SZ02
names: Similarity
messages: Belongs to the MlaA family.

357804:PING RS16510
gene id: 357804:PING_RS16510
uniprot id: A1SZH5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. DeaD/CsdA subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation.

357804:PING RS11825
gene id: 357804:PING_RS11825
uniprot id: A1SX20
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Homodimer.

357804:PING RS16595
gene id: 357804:PING_RS16595
uniprot id: A1SZJ2
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

357804:PING RS08210
gene id: 357804:PING_RS08210
uniprot id: A1SV55
names: Subcellular Location Annotation
messages: Membrane

357804:PING RS11400
gene id: 357804:PING_RS11400
uniprot id: A1SWT7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

357804:PING RS16655
gene id: 357804:PING_RS16655
uniprot id: A1SZK4
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

357804:PING RS04090
gene id: 357804:PING_RS04090
uniprot id: A1ST07
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

357804:PING RS03910
gene id: 357804:PING_RS03910
uniprot id: A1SSX9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

357804:PING RS00325
gene id: 357804:PING_RS00325
uniprot id: A1SR15
names: Similarity
messages: Belongs to the UPF0758 family.

357804:PING RS11210
gene id: 357804:PING_RS11210
uniprot id: A1SWP8
names: Cofactor
names: PTM
names: Similarity
messages: Belongs to the NapC/NirT/NrfH family.
messages: Binds 4 heme groups per subunit.

357804:PING RS02420
gene id: 357804:PING_RS02420
uniprot id: A1SS53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

357804:PING RS07470
gene id: 357804:PING_RS07470
uniprot id: A1SUR8
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

357804:PING RS10970
gene id: 357804:PING_RS10970
uniprot id: A1SWK2
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

357804:PING RS14280
gene id: 357804:PING_RS14280
uniprot id: A1SYA8
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

357804:PING RS11285
gene id: 357804:PING_RS11285
uniprot id: A1SWR4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ProQ family.
messages: Cytoplasm
messages: RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities.

357804:PING RS05430
gene id: 357804:PING_RS05430
uniprot id: A1STP6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

357804:PING RS19230
gene id: 357804:PING_RS19230
uniprot id: A1T0Z1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

357804:PING RS11175
gene id: 357804:PING_RS11175
uniprot id: A1SWP1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

357804:PING RS01120
gene id: 357804:PING_RS01120
uniprot id: A1SRG4
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

357804:PING RS08815
gene id: 357804:PING_RS08815
uniprot id: A1SVF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Membrane

357804:PING RS11380
gene id: 357804:PING_RS11380
uniprot id: A1SWT3
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

357804:PING RS06745
gene id: 357804:PING_RS06745
uniprot id: A1SUE0
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

357804:PING RS07345
gene id: 357804:PING_RS07345
uniprot id: A1SUP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell inner membrane
messages: Membrane

357804:PING RS08825
gene id: 357804:PING_RS08825
uniprot id: A1SVG1
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

357804:PING RS19225
gene id: 357804:PING_RS19225
uniprot id: A1T0Z0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

357804:PING RS12265
gene id: 357804:PING_RS12265
uniprot id: A1SXA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial glucokinase family.
messages: Cytoplasm

357804:PING RS01820
gene id: 357804:PING_RS01820
uniprot id: A1SRU0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

357804:PING RS00660
gene id: 357804:PING_RS00660
uniprot id: A1SR77
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation.
messages: Cytoplasm

357804:PING RS09815
gene id: 357804:PING_RS09815
uniprot id: A1SVZ5
names: Similarity
messages: Belongs to the Nudix hydrolase family.

357804:PING RS10565
gene id: 357804:PING_RS10565
uniprot id: A1SWD2
names: Similarity
messages: Belongs to the UDP-galactopyranose/dTDP-fucopyranose mutase family.

357804:PING RS10160
gene id: 357804:PING_RS10160
uniprot id: A1SW62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

357804:PING RS18655
gene id: 357804:PING_RS18655
uniprot id: A1T0N4
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

357804:PING RS03720
gene id: 357804:PING_RS03720
uniprot id: A1SSU6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

357804:PING RS16245
gene id: 357804:PING_RS16245
uniprot id: A1SZC7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

357804:PING RS03305
gene id: 357804:PING_RS03305
uniprot id: A1SSL4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoH subfamily.
messages: Cytoplasm
messages: Interacts with the RNA polymerase core enzyme.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.

357804:PING RS00495
gene id: 357804:PING_RS00495
uniprot id: A1SR44
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

357804:PING RS19505
gene id: 357804:PING_RS19505
uniprot id: A1SWC0
names: Subcellular Location Annotation
messages: Membrane

357804:PING RS12595
gene id: 357804:PING_RS12595
uniprot id: A1SXF8
names: Similarity
messages: Belongs to the ArsC family.

357804:PING RS09675
gene id: 357804:PING_RS09675
uniprot id: A1SVW8
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

357804:PING RS07785
gene id: 357804:PING_RS07785
uniprot id: A1SUY0
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

357804:PING RS10130
gene id: 357804:PING_RS10130
uniprot id: A1SW56
names: Subcellular Location Annotation
messages: Membrane

357804:PING RS16800
gene id: 357804:PING_RS16800
uniprot id: A1SZN1
names: Similarity
messages: Belongs to the DEAD box helicase family.

357804:PING RS11335
gene id: 357804:PING_RS11335
uniprot id: A1SWS4
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TtcA family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is chelated by three Cys residues, the fourth Fe has a free coordination site that may bind a sulfur atom transferred from the persulfide of IscS.
messages: Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
messages: Cytoplasm
messages: Homodimer.
messages: The thiolation reaction likely consists of two steps: a first activation step by ATP to form an adenylated intermediate of the target base of tRNA, and a second nucleophilic substitution step of the sulfur (S) atom supplied by the hydrosulfide attached to the Fe-S cluster.

357804:PING RS13620
gene id: 357804:PING_RS13620
uniprot id: A1SXY8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

357804:PING RS08835
gene id: 357804:PING_RS08835
uniprot id: A1SVG3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thioester dehydratase family. FabA subfamily.
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Cytoplasm
messages: Homodimer.

357804:PING RS09200
gene id: 357804:PING_RS09200
uniprot id: A1SVM8
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

357804:PING RS10825
gene id: 357804:PING_RS10825
uniprot id: A1SWH8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. UgpAE subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Part of the binding-protein-dependent transport system for sn-glycerol-3-phosphate; probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (UgpC), two transmembrane proteins (UgpA and UgpE) and a solute-binding protein (UgpB).

357804:PING RS17265
gene id: 357804:PING_RS17265
uniprot id: A1SZW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

357804:PING RS12540
gene id: 357804:PING_RS12540
uniprot id: A1SXE7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

357804:PING RS00085
gene id: 357804:PING_RS00085
uniprot id: A1SQX0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

357804:PING RS14365
gene id: 357804:PING_RS14365
uniprot id: A1SYC5
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

357804:PING RS09090
gene id: 357804:PING_RS09090
uniprot id: A1SVK7
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

357804:PING RS01020
gene id: 357804:PING_RS01020
uniprot id: A1SRE5
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins.

357804:PING RS14670
gene id: 357804:PING_RS14670
uniprot id: A1SYI6
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

357804:PING RS03730
gene id: 357804:PING_RS03730
uniprot id: A1SSU8
names: Similarity
messages: Belongs to the SfsA family.

357804:PING RS15685
gene id: 357804:PING_RS15685
uniprot id: A1SZ32
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

357804:PING RS08325
gene id: 357804:PING_RS08325
uniprot id: A1SV75
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

357804:PING RS13460
gene id: 357804:PING_RS13460
uniprot id: A1SXW1
names: Similarity
messages: Belongs to the flavin oxidoreductase frp family.

357804:PING RS05610
gene id: 357804:PING_RS05610
uniprot id: A1STT1
names: Function
names: Similarity
messages: Belongs to the TrpC family.
messages: Belongs to the TrpF family.
messages: Bifunctional enzyme that catalyzes two sequential steps of tryptophan biosynthetic pathway. The first reaction is catalyzed by the isomerase, coded by the TrpF domain; the second reaction is catalyzed by the synthase, coded by the TrpC domain.
messages: In the C-terminal section; belongs to the TrpF family.
messages: In the N-terminal section; belongs to the TrpC family.

357804:PING RS15440
gene id: 357804:PING_RS15440
uniprot id: A1SYY4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
messages: Cytoplasm
messages: Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
messages: Homodimer. UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

357804:PING RS04795
gene id: 357804:PING_RS04795
uniprot id: A1STD9
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

357804:PING RS16920
gene id: 357804:PING_RS16920
uniprot id: A1SZQ4
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of Lys-34 is required for alleviation.
messages: May be beta-lysylated on the epsilon-amino group of Lys-34 by the combined action of EpmA and EpmB, and then hydroxylated on the C5 position of the same residue by EpmC (if this protein is present). Lysylation is critical for the stimulatory effect of EF-P on peptide-bond formation. The lysylation moiety may extend toward the peptidyltransferase center and stabilize the terminal 3-CCA end of the tRNA. Hydroxylation of the C5 position on Lys-34 may allow additional potential stabilizing hydrogen-bond interactions with the P-tRNA.

357804:PING RS00460
gene id: 357804:PING_RS00460
uniprot id: A1SR37
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

357804:PING RS16535
gene id: 357804:PING_RS16535
uniprot id: A1SZI0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecB family.
messages: Cytoplasm
messages: Homotetramer, a dimer of dimers. One homotetramer interacts with 1 SecA dimer.
messages: One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.

357804:PING RS07020
gene id: 357804:PING_RS07020
uniprot id: A1SUI4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
messages: Cytoplasm
messages: Homodimer. Forms a heterotetramer with IscU, interacts with other sulfur acceptors.
messages: Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.

357804:PING RS05905
gene id: 357804:PING_RS05905
uniprot id: A1STY7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

357804:PING RS16230
gene id: 357804:PING_RS16230
uniprot id: A1SZC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

357804:PING RS14285
gene id: 357804:PING_RS14285
uniprot id: A1SYA9
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

357804:PING RS04625
gene id: 357804:PING_RS04625
uniprot id: A1STA6
names: Similarity
messages: Belongs to the phosphohexose mutase family.

357804:PING RS03915
gene id: 357804:PING_RS03915
uniprot id: A1SSY0
names: Similarity
messages: Belongs to the ClpA/ClpB family.

357804:PING RS02970
gene id: 357804:PING_RS02970
uniprot id: A1SSF4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNT beta subunit family.
messages: Cell inner membrane
messages: Heterodimer of an alpha and a beta chain.
messages: Membrane
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

357804:PING RS18790
gene id: 357804:PING_RS18790
uniprot id: A1T0R2
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

357804:PING RS02730
gene id: 357804:PING_RS02730
uniprot id: A1SSA8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase II family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.

357804:PING RS02005
gene id: 357804:PING_RS02005
uniprot id: A1SRX1
names: Function
names: Similarity
messages: Belongs to the Fe(2+)-trafficking protein family.
messages: Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.

357804:PING RS10255
gene id: 357804:PING_RS10255
uniprot id: A1SW79
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

357804:PING RS10910
gene id: 357804:PING_RS10910
uniprot id: A1SWJ1
names: Similarity
messages: Belongs to the CIA30 family.

357804:PING RS06295
gene id: 357804:PING_RS06295
uniprot id: A1SU59
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LptE lipoprotein family.
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptD.
messages: Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane.

357804:PING RS17310
gene id: 357804:PING_RS17310
uniprot id: A1SZX6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family. ParE type 1 subfamily.
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

357804:PING RS02735
gene id: 357804:PING_RS02735
uniprot id: A1SSA9
names: Similarity
messages: Belongs to the pirin family.

357804:PING RS01875
gene id: 357804:PING_RS01875
uniprot id: A1SRV0
names: Caution
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
messages: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

357804:PING RS01865
gene id: 357804:PING_RS01865
uniprot id: A1SRU9
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

357804:PING RS15265
gene id: 357804:PING_RS15265
uniprot id: A1SYV0
names: Function
names: Similarity
messages: Belongs to the LpxB family.
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

357804:PING RS06135
gene id: 357804:PING_RS06135
uniprot id: A1SU33
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA gyrase inhibitor YacG family.
messages: Binds 1 zinc ion.
messages: Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.
messages: Interacts with GyrB.

357804:PING RS12635
gene id: 357804:PING_RS12635
uniprot id: A1SXG6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase T family.
messages: Binds two Mg(2+) per subunit. The active form of the enzyme binds two Mg(2+) ions in its active site. The first Mg(2+) forms only one salt bridge with the protein.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis.

357804:PING RS01115
gene id: 357804:PING_RS01115
uniprot id: A1SRG3
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

357804:PING RS07780
gene id: 357804:PING_RS07780
uniprot id: A1SUX9
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

357804:PING RS13570
gene id: 357804:PING_RS13570
uniprot id: A1SXY0
names: Similarity
messages: Belongs to the alkaline phosphatase family.

357804:PING RS03410
gene id: 357804:PING_RS03410
uniprot id: A1SSN5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

357804:PING RS05735
gene id: 357804:PING_RS05735
uniprot id: A1STV6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

357804:PING RS00240
gene id: 357804:PING_RS00240
uniprot id: A1SR00
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

357804:PING RS06780
gene id: 357804:PING_RS06780
uniprot id: A1SUE7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

357804:PING RS07010
gene id: 357804:PING_RS07010
uniprot id: A1SUI2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.
messages: Cytoplasm
messages: Homodimer.

357804:PING RS18195
gene id: 357804:PING_RS18195
uniprot id: A1T0E0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

357804:PING RS07165
gene id: 357804:PING_RS07165
uniprot id: A1SUL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

357804:PING RS11355
gene id: 357804:PING_RS11355
uniprot id: A1SWS8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family.
messages: Cell inner membrane
messages: Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.
messages: The complex is composed of two ATP-binding proteins (LolD) and two transmembrane proteins (LolC and LolE).

357804:PING RS12060
gene id: 357804:PING_RS12060
uniprot id: A1SX65
names: Subcellular Location Annotation
messages: Membrane

357804:PING RS02565
gene id: 357804:PING_RS02565
uniprot id: A1SS82
names: Subcellular Location Annotation
messages: Membrane

357804:PING RS18310
gene id: 357804:PING_RS18310
uniprot id: A1T0G3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

357804:PING RS11155
gene id: 357804:PING_RS11155
uniprot id: A1SWN7
names: Similarity
messages: Belongs to the GST superfamily.

357804:PING RS09615
gene id: 357804:PING_RS09615
uniprot id: A1SVV6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

357804:PING RS07835
gene id: 357804:PING_RS07835
uniprot id: A1SUY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uridine kinase family.
messages: Cytoplasm

357804:PING RS03865
gene id: 357804:PING_RS03865
uniprot id: A1SSX1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RnfG family.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

357804:PING RS08640
gene id: 357804:PING_RS08640
uniprot id: A1SVC5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

357804:PING RS13925
gene id: 357804:PING_RS13925
uniprot id: A1SY42
names: Similarity
messages: Belongs to the histone deacetylase family.

357804:PING RS03450
gene id: 357804:PING_RS03450
uniprot id: A1SSP3
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

357804:PING RS11705
gene id: 357804:PING_RS11705
uniprot id: A1SWZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNR ribonuclease family. RNase II subfamily.
messages: Cytoplasm
messages: Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction.

357804:PING RS04195
gene id: 357804:PING_RS04195
uniprot id: A1ST27
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: With CysD forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

357804:PING RS14600
gene id: 357804:PING_RS14600
uniprot id: A1SYH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane

357804:PING RS01975
gene id: 357804:PING_RS01975
uniprot id: A1SRW8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.

357804:PING RS05955
gene id: 357804:PING_RS05955
uniprot id: A1STZ7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

357804:PING RS19275
gene id: 357804:PING_RS19275
uniprot id: A1T100
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

357804:PING RS17000
gene id: 357804:PING_RS17000
uniprot id: A1SZR6
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

357804:PING RS04060
gene id: 357804:PING_RS04060
uniprot id: A1ST01
names: Similarity
messages: Belongs to the phosphohexose mutase family.

357804:PING RS02555
gene id: 357804:PING_RS02555
uniprot id: A1SS80
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

357804:PING RS12920
gene id: 357804:PING_RS12920
uniprot id: A1SXL4
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

357804:PING RS18640
gene id: 357804:PING_RS18640
uniprot id: A1T0N1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Gram-negative porin family.
messages: Cell outer membrane
messages: Membrane

357804:PING RS08745
gene id: 357804:PING_RS08745
uniprot id: A1SVE7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

357804:PING RS10465
gene id: 357804:PING_RS10465
uniprot id: A1SWB7
names: Similarity
messages: Belongs to the aldose epimerase family.

357804:PING RS01200
gene id: 357804:PING_RS01200
uniprot id: A1SRH7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfur carrier protein TusA family.
messages: Cytoplasm
messages: Sulfur carrier protein which probably makes part of a sulfur-relay system.

357804:PING RS15130
gene id: 357804:PING_RS15130
uniprot id: A1SYS3
names: Similarity
messages: Belongs to the gluconokinase GntK/GntV family.

357804:PING RS11360
gene id: 357804:PING_RS11360
uniprot id: A1SWS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

357804:PING RS08550
gene id: 357804:PING_RS08550
uniprot id: A1SVA9
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

357804:PING RS09715
gene id: 357804:PING_RS09715
uniprot id: A1SVX5
names: Subcellular Location Annotation
messages: Cytoplasm

357804:PING RS03740
gene id: 357804:PING_RS03740
uniprot id: A1SSV1
names: Subcellular Location Annotation
messages: Membrane

357804:PING RS17920
gene id: 357804:PING_RS17920
uniprot id: A1T085
names: Subcellular Location Annotation
messages: Membrane

357804:PING RS08405
gene id: 357804:PING_RS08405
uniprot id: A1SV89
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

357804:PING RS18080
gene id: 357804:PING_RS18080
uniprot id: A1T0B7
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

357804:PING RS02475
gene id: 357804:PING_RS02475
uniprot id: A1SS64
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

357804:PING RS14110
gene id: 357804:PING_RS14110
uniprot id: A1SY80
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

357804:PING RS07710
gene id: 357804:PING_RS07710
uniprot id: A1SUW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell inner membrane
messages: Membrane

357804:PING RS15790
gene id: 357804:PING_RS15790
uniprot id: A1SZ54
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

357804:PING RS07675
gene id: 357804:PING_RS07675
uniprot id: A1SUV7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine.

357804:PING RS15100
gene id: 357804:PING_RS15100
uniprot id: A1SYR7
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

357804:PING RS05560
gene id: 357804:PING_RS05560
uniprot id: A1STS1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

357804:PING RS18490
gene id: 357804:PING_RS18490
uniprot id: A1T0K0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell inner membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

357804:PING RS11280
gene id: 357804:PING_RS11280
uniprot id: A1SWR3
names: Similarity
messages: Belongs to the peptidase S41A family.

357804:PING RS10570
gene id: 357804:PING_RS10570
uniprot id: A1SWD3
names: Subcellular Location Annotation
messages: Membrane

357804:PING RS08665
gene id: 357804:PING_RS08665
uniprot id: A1SVD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

357804:PING RS04530
gene id: 357804:PING_RS04530
uniprot id: A1ST87
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

357804:PING RS04535
gene id: 357804:PING_RS04535
uniprot id: A1ST88
names: Caution
names: Function
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.
messages: Catalyzes the biosynthesis of agmatine from arginine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

357804:PING RS14345
gene id: 357804:PING_RS14345
uniprot id: A1SYC1
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

357804:PING RS07185
gene id: 357804:PING_RS07185
uniprot id: A1SUL7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

357804:PING RS14830
gene id: 357804:PING_RS14830
uniprot id: A1SYL6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

357804:PING RS02975
gene id: 357804:PING_RS02975
uniprot id: A1SSF5
names: Function
names: Similarity
messages: Belongs to the AlaDH/PNT family.
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

357804:PING RS01140
gene id: 357804:PING_RS01140
uniprot id: A1SRG8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homotetramer.

357804:PING RS17045
gene id: 357804:PING_RS17045
uniprot id: A1SZS5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbC subfamily.
messages: Periplasm
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process.

357804:PING RS18115
gene id: 357804:PING_RS18115
uniprot id: A1T0C4
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

357804:PING RS07240
gene id: 357804:PING_RS07240
uniprot id: A1SUM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

357804:PING RS16715
gene id: 357804:PING_RS16715
uniprot id: A1SZL5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

357804:PING RS08970
gene id: 357804:PING_RS08970
uniprot id: A1SVI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Membrane

357804:PING RS02550
gene id: 357804:PING_RS02550
uniprot id: A1SS79
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

357804:PING RS00055
gene id: 357804:PING_RS00055
uniprot id: A1SQW4
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

357804:PING RS11660
gene id: 357804:PING_RS11660
uniprot id: A1SWY8
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

357804:PING RS07725
gene id: 357804:PING_RS07725
uniprot id: A1SUW8
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

357804:PING RS09115
gene id: 357804:PING_RS09115
uniprot id: A1SVL3
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

357804:PING RS01345
gene id: 357804:PING_RS01345
uniprot id: A1SRJ8
names: Similarity
messages: Belongs to the site-specific recombinase resolvase family.

357804:PING RS02870
gene id: 357804:PING_RS02870
uniprot id: A1SSD5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

357804:PING RS16630
gene id: 357804:PING_RS16630
uniprot id: A1SZJ9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

357804:PING RS01570
gene id: 357804:PING_RS01570
uniprot id: A1SRP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

357804:PING RS18520
gene id: 357804:PING_RS18520
uniprot id: A1T0K6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

357804:PING RS05180
gene id: 357804:PING_RS05180
uniprot id: A1STJ7
names: Subcellular Location Annotation
messages: Membrane

357804:PING RS11310
gene id: 357804:PING_RS11310
uniprot id: A1SWR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

357804:PING RS17355
gene id: 357804:PING_RS17355
uniprot id: A1SZY5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

357804:PING RS14230
gene id: 357804:PING_RS14230
uniprot id: A1SYA1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

357804:PING RS10285
gene id: 357804:PING_RS10285
uniprot id: A1SW85
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thioester dehydratase family. FabA subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length.

357804:PING RS17910
gene id: 357804:PING_RS17910
uniprot id: A1T083
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

357804:PING RS17855
gene id: 357804:PING_RS17855
uniprot id: A1T073
names: Subcellular Location Annotation
messages: Membrane

357804:PING RS10450
gene id: 357804:PING_RS10450
uniprot id: A1SWB4
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

357804:PING RS15690
gene id: 357804:PING_RS15690
uniprot id: A1SZ33
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

357804:PING RS13515
gene id: 357804:PING_RS13515
uniprot id: A1SXX2
names: Subcellular Location Annotation
messages: Membrane

357804:PING RS14815
gene id: 357804:PING_RS14815
uniprot id: A1SYL4
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The Rieske protein is a high potential 2Fe-2S protein.
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

357804:PING RS00930
gene id: 357804:PING_RS00930
uniprot id: A1SRC7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell inner membrane

357804:PING RS08680
gene id: 357804:PING_RS08680
uniprot id: A1SVD3
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

357804:PING RS14170
gene id: 357804:PING_RS14170
uniprot id: A1SY89
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily.
messages: Homodimer.
messages: Involved in phosphonate degradation.

357804:PING RS01680
gene id: 357804:PING_RS01680
uniprot id: A1SRR2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

357804:PING RS18165
gene id: 357804:PING_RS18165
uniprot id: A1T0D4
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

357804:PING RS03510
gene id: 357804:PING_RS03510
uniprot id: A1SSQ6
names: Activity Regulation
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.

357804:PING RS14930
gene id: 357804:PING_RS14930
uniprot id: A1SYN6
names: Similarity
messages: Belongs to the UPF0231 family.

357804:PING RS00995
gene id: 357804:PING_RS00995
uniprot id: A1SRE0
names: Function
names: Similarity
messages: Belongs to the GlnE family.
messages: Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell.

357804:PING RS10945
gene id: 357804:PING_RS10945
uniprot id: A1SWJ8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

357804:PING RS16265
gene id: 357804:PING_RS16265
uniprot id: A1SZD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

357804:PING RS13990
gene id: 357804:PING_RS13990
uniprot id: A1SY55
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell inner membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.

357804:PING RS01395
gene id: 357804:PING_RS01395
uniprot id: A1SRK8
names: Similarity
messages: Belongs to the thiolase-like superfamily. Chalcone/stilbene synthases family.

357804:PING RS15420
gene id: 357804:PING_RS15420
uniprot id: A1SYY0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease beta subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

357804:PING RS06080
gene id: 357804:PING_RS06080
uniprot id: A1SU22
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsQ/DivIB family. FtsQ subfamily.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly.
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

357804:PING RS08940
gene id: 357804:PING_RS08940
uniprot id: A1SVH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

357804:PING RS04495
gene id: 357804:PING_RS04495
uniprot id: A1ST80
names: Caution
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

357804:PING RS01775
gene id: 357804:PING_RS01775
uniprot id: A1SRT1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. KdkA/RfaP family.
messages: Catalyzes the ATP-dependent phosphorylation of the 3-deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position.
messages: Cell inner membrane
messages: Membrane

357804:PING RS07765
gene id: 357804:PING_RS07765
uniprot id: A1SUX6
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

357804:PING RS01040
gene id: 357804:PING_RS01040
uniprot id: A1SRE9
names: Similarity
messages: Belongs to the IMPACT family.

357804:PING RS07950
gene id: 357804:PING_RS07950
uniprot id: A1SV11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

357804:PING RS05750
gene id: 357804:PING_RS05750
uniprot id: A1STV9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

357804:PING RS15525
gene id: 357804:PING_RS15525
uniprot id: A1SZ00
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS1 family.
messages: Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.

357804:PING RS17590
gene id: 357804:PING_RS17590
uniprot id: A1T026
names: Function
names: Similarity
messages: Belongs to the TrhO family.
messages: Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.

357804:PING RS18645
gene id: 357804:PING_RS18645
uniprot id: A1T0N2
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

357804:PING RS14330
gene id: 357804:PING_RS14330
uniprot id: A1SYB8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Xni family.
messages: Binds 1 K(+) per subunit. The potassium ion strongly increases the affinity for DNA.
messages: Binds 2 Mg(2+) per subunit. Only one magnesium ion has a direct interaction with the protein, the other interactions are indirect.
messages: Has flap endonuclease activity. During DNA replication, flap endonucleases cleave the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment.

357804:PING RS06945
gene id: 357804:PING_RS06945
uniprot id: A1SUH1
names: PTM
messages: Binds 2 heme c groups covalently per subunit.

357804:PING RS18355
gene id: 357804:PING_RS18355
uniprot id: A1T0H2
names: Similarity
messages: Belongs to the LacAB/RpiB family.

357804:PING RS14565
gene id: 357804:PING_RS14565
uniprot id: A1SYG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

357804:PING RS16675
gene id: 357804:PING_RS16675
uniprot id: A1SZK7
names: Function
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflC subfamily.
messages: HflC and HflK could regulate a protease.

357804:PING RS16425
gene id: 357804:PING_RS16425
uniprot id: A1SZG3
names: Similarity
messages: Belongs to the thioredoxin family.

357804:PING RS11805
gene id: 357804:PING_RS11805
uniprot id: A1SX16
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. NspC subfamily.
messages: Catalyzes the decarboxylation of carboxynorspermidine and carboxyspermidine.
messages: Cytoplasm
messages: Homodimer.

357804:PING RS03365
gene id: 357804:PING_RS03365
uniprot id: A1SSM6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell inner membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

357804:PING RS05605
gene id: 357804:PING_RS05605
uniprot id: A1STT0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

357804:PING RS06695
gene id: 357804:PING_RS06695
uniprot id: A1SUD1
names: Subcellular Location Annotation
messages: Membrane

357804:PING RS11200
gene id: 357804:PING_RS11200
uniprot id: A1SWP6
names: Function
names: Similarity
messages: Belongs to the MoaB/Mog family.
messages: May be involved in the biosynthesis of molybdopterin.

357804:PING RS16850
gene id: 357804:PING_RS16850
uniprot id: A1SZP1
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

357804:PING RS19115
gene id: 357804:PING_RS19115
uniprot id: A1T0W9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

357804:PING RS18550
gene id: 357804:PING_RS18550
uniprot id: A1T0L2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

357804:PING RS04790
gene id: 357804:PING_RS04790
uniprot id: A1STD8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

357804:PING RS13115
gene id: 357804:PING_RS13115
uniprot id: A1SXQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Set transporter family.
messages: Membrane

357804:PING RS07715
gene id: 357804:PING_RS07715
uniprot id: A1SUW6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

357804:PING RS05565
gene id: 357804:PING_RS05565
uniprot id: A1STS2
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PdxA family.
messages: Binds 1 divalent metal cation per subunit. Can use ions such as Zn(2+), Mg(2+) or Co(2+).
messages: Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).
messages: Cytoplasm
messages: Homodimer.
messages: The active site is located at the dimer interface.

357804:PING RS06325
gene id: 357804:PING_RS06325
uniprot id: A1SU63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

357804:PING RS19155
gene id: 357804:PING_RS19155
uniprot id: A1T0X7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

357804:PING RS14950
gene id: 357804:PING_RS14950
uniprot id: A1SYP0
names: Function
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. S-2-haloalkanoic acid dehalogenase family.
messages: Catalyzes the hydrolytic dehalogenation of small (S)-2-haloalkanoic acids to yield the corresponding (R)-2-hydroxyalkanoic acids.

357804:PING RS11760
gene id: 357804:PING_RS11760
uniprot id: A1SX07
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCF family. Uup subfamily.
messages: Cytoplasm
messages: Probably plays a role in ribosome assembly or function. May be involved in resolution of branched DNA intermediates that result from template switching in postreplication gaps. Binds DNA and has ATPase activity.

357804:PING RS13580
gene id: 357804:PING_RS13580
uniprot id: A1SXY2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

357804:PING RS06015
gene id: 357804:PING_RS06015
uniprot id: A1SU09
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein L14 (rplN).

357804:PING RS09850
gene id: 357804:PING_RS09850
uniprot id: A1SW02
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gluconeogenesis factor family.
messages: Cytoplasm
messages: Required for morphogenesis under gluconeogenic growth conditions.

357804:PING RS05810
gene id: 357804:PING_RS05810
uniprot id: A1STX1
names: Subcellular Location Annotation
messages: Cytoplasm

357804:PING RS18190
gene id: 357804:PING_RS18190
uniprot id: A1T0D9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

357804:PING RS19620
gene id: 357804:PING_RS19620
uniprot id: A1SZM2
names: Similarity
messages: Belongs to the ice-binding protein family.

357804:PING RS05100
gene id: 357804:PING_RS05100
uniprot id: A1STI2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Molecular chaperone. Has ATPase activity.

357804:PING RS16970
gene id: 357804:PING_RS16970
uniprot id: A1SZR0
names: Subcellular Location Annotation
messages: Membrane

357804:PING RS18425
gene id: 357804:PING_RS18425
uniprot id: A1T0I7
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

357804:PING RS05900
gene id: 357804:PING_RS05900
uniprot id: A1STY6
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
messages: O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.

357804:PING RS02200
gene id: 357804:PING_RS02200
uniprot id: A1SS09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

357804:PING RS15600
gene id: 357804:PING_RS15600
uniprot id: A1SZ15
names: Similarity
messages: Belongs to the UPF0250 family.

357804:PING RS05765
gene id: 357804:PING_RS05765
uniprot id: A1STW2
names: Similarity
messages: Belongs to the fabD family.

357804:PING RS16590
gene id: 357804:PING_RS16590
uniprot id: A1SZJ1
names: Similarity
messages: Belongs to the GARS family.

357804:PING RS05710
gene id: 357804:PING_RS05710
uniprot id: A1STV1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MinC family.
messages: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.
messages: Interacts with MinD and FtsZ.

357804:PING RS21180
gene id: 357804:PING_RS21180
uniprot id: A1T0L9
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

357804:PING RS08115
gene id: 357804:PING_RS08115
uniprot id: A1SV44
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

357804:PING RS17625
gene id: 357804:PING_RS17625
uniprot id: A1T033
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

357804:PING RS02820
gene id: 357804:PING_RS02820
uniprot id: A1SSC6
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.
messages: Homotetramer.

357804:PING RS19205
gene id: 357804:PING_RS19205
uniprot id: A1T0Y6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

357804:PING RS18215
gene id: 357804:PING_RS18215
uniprot id: A1T0E4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TmcA family.
messages: Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: nucleolus

357804:PING RS00310
gene id: 357804:PING_RS00310
uniprot id: A1SR12
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

357804:PING RS03250
gene id: 357804:PING_RS03250
uniprot id: A1SSK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

357804:PING RS01825
gene id: 357804:PING_RS01825
uniprot id: A1SRU1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbsD / FucU family. RbsD subfamily.
messages: Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose.
messages: Cytoplasm
messages: Homodecamer.

357804:PING RS16055
gene id: 357804:PING_RS16055
uniprot id: A1SZA2
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.

357804:PING RS10420
gene id: 357804:PING_RS10420
uniprot id: A1SWA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

357804:PING RS15610
gene id: 357804:PING_RS15610
uniprot id: A1SZ17
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

357804:PING RS20870
gene id: 357804:PING_RS20870
uniprot id: A2BNC4
names: Similarity
messages: Belongs to the HepT RNase toxin family.

357804:PING RS13485
gene id: 357804:PING_RS13485
uniprot id: A1SXW6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

357804:PING RS10090
gene id: 357804:PING_RS10090
uniprot id: A1SW48
names: Function
messages: Mediates the mercuric-dependent induction of mercury resistance operon. In the absence of mercury MerR represses transcription by binding tightly to the mer operator region; when mercury is present the dimeric complex binds a single ion and becomes a potent transcriptional activator, while remaining bound to the mer site.

357804:PING RS04915
gene id: 357804:PING_RS04915
uniprot id: A1STG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

357804:PING RS15010
gene id: 357804:PING_RS15010
uniprot id: A1SYQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

357804:PING RS09985
gene id: 357804:PING_RS09985
uniprot id: A1SW28
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

357804:PING RS16900
gene id: 357804:PING_RS16900
uniprot id: A1SZQ0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Part of an enzyme complex containing four subunits: a flavoprotein (FrdA), an iron-sulfur protein (FrdB), and two hydrophobic anchor proteins (FrdC and FrdD).

357804:PING RS19235
gene id: 357804:PING_RS19235
uniprot id: A1T0Z2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase delta chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

357804:PING RS16955
gene id: 357804:PING_RS16955
uniprot id: A1SZQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gmhB family.
messages: Cytoplasm

357804:PING RS10515
gene id: 357804:PING_RS10515
uniprot id: A1SWC5
names: Similarity
messages: Belongs to the RutC family.

357804:PING RS03815
gene id: 357804:PING_RS03815
uniprot id: A1SSW6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpoB family.
messages: Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division.
messages: Periplasm

357804:PING RS01835
gene id: 357804:PING_RS01835
uniprot id: A1SRU3
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

357804:PING RS08725
gene id: 357804:PING_RS08725
uniprot id: A1SVE3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell inner membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

357804:PING RS17195
gene id: 357804:PING_RS17195
uniprot id: A1SZV6
names: Similarity
messages: Belongs to the diaminopimelate epimerase family.

357804:PING RS08200
gene id: 357804:PING_RS08200
uniprot id: A1SV54
names: Function
names: Similarity
messages: Belongs to the SELO family.
messages: Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).

357804:PING RS11255
gene id: 357804:PING_RS11255
uniprot id: A1SWQ8
names: Similarity
messages: Belongs to the acylphosphatase family.

357804:PING RS15890
gene id: 357804:PING_RS15890
uniprot id: A1SZ74
names: Subcellular Location Annotation
messages: Membrane

357804:PING RS18345
gene id: 357804:PING_RS18345
uniprot id: A1T0H0
names: Function
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.
messages: Catalyzes the ATP-dependent phosphorylation of fructose-l-phosphate to fructose-l,6-bisphosphate.

357804:PING RS06160
gene id: 357804:PING_RS06160
uniprot id: A1SU36
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.

357804:PING RS16975
gene id: 357804:PING_RS16975
uniprot id: A1SZR1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

357804:PING RS09740
gene id: 357804:PING_RS09740
uniprot id: A1SVY0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.
messages: Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate.
messages: Homotetramer; dimer of dimers.
messages: Involved in the catabolism of short chain fatty acids (SCFA) via the 2-methylcitrate cycle (propionate degradation route). Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate via an alpha-carboxy-carbanion intermediate.

357804:PING RS10260
gene id: 357804:PING_RS10260
uniprot id: A1SW80
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I fumarase family.
messages: Catalyzes the reversible hydration of fumarate to (S)-malate.
messages: Homodimer.

357804:PING RS18410
gene id: 357804:PING_RS18410
uniprot id: A1T0I4
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

357804:PING RS03400
gene id: 357804:PING_RS03400
uniprot id: A1SSN3
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

357804:PING RS10645
gene id: 357804:PING_RS10645
uniprot id: A1SWE3
names: Subcellular Location Annotation
messages: Membrane

357804:PING RS10930
gene id: 357804:PING_RS10930
uniprot id: A1SWJ5
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

357804:PING RS16325
gene id: 357804:PING_RS16325
uniprot id: A1SZE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

357804:PING RS01105
gene id: 357804:PING_RS01105
uniprot id: A1SRG1
names: Function
names: Similarity
names: Subunit
messages: A GTPase-activating protein (GAP) that modifies Der/EngA GTPase function. May play a role in ribosome biogenesis.
messages: Belongs to the YihI family.
messages: Interacts with Der.

357804:PING RS01880
gene id: 357804:PING_RS01880
uniprot id: A1SRV1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MenH family.
messages: Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC).
messages: Monomer.

357804:PING RS10345
gene id: 357804:PING_RS10345
uniprot id: A1SW95
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

357804:PING RS04805
gene id: 357804:PING_RS04805
uniprot id: A1STE1
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

357804:PING RS10585
gene id: 357804:PING_RS10585
uniprot id: A1SWD6
names: Similarity
messages: Belongs to the Dps family.

357804:PING RS15235
gene id: 357804:PING_RS15235
uniprot id: A1SYU4
names: Subcellular Location Annotation
messages: Membrane

357804:PING RS16855
gene id: 357804:PING_RS16855
uniprot id: A1SZP2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell inner membrane
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

357804:PING RS09050
gene id: 357804:PING_RS09050
uniprot id: A1SVJ9
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

357804:PING RS14625
gene id: 357804:PING_RS14625
uniprot id: A1SYH7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmJ family.
messages: Cytoplasm
messages: Specifically methylates the guanosine in position 1516 of 16S rRNA.

357804:PING RS00295
gene id: 357804:PING_RS00295
uniprot id: A1SR09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

357804:PING RS08445
gene id: 357804:PING_RS08445
uniprot id: A1SV97
names: Similarity
messages: Belongs to the YkuD family.

357804:PING RS08410
gene id: 357804:PING_RS08410
uniprot id: A1SV90
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

357804:PING RS07150
gene id: 357804:PING_RS07150
uniprot id: A1SUL0
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

357804:PING RS06620
gene id: 357804:PING_RS06620
uniprot id: A1SUB7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gas vesicle protein type A family.
messages: Gas vesicles are small, hollow, gas filled protein structures that are found in several microbial planktonic microorganisms. They allow the positioning of the organism at the favorable depth for growth. GvpA type proteins form the essential core of the structure.
messages: gas vesicle membrane

357804:PING RS10940
gene id: 357804:PING_RS10940
uniprot id: A1SWJ7
names: Similarity
messages: Belongs to the proline racemase family.

357804:PING RS06790
gene id: 357804:PING_RS06790
uniprot id: A1SUE9
names: Similarity
messages: Belongs to the prokaryotic GSH synthase family.

357804:PING RS04675
gene id: 357804:PING_RS04675
uniprot id: A1STB5
names: Subcellular Location Annotation
messages: Membrane

357804:PING RS04715
gene id: 357804:PING_RS04715
uniprot id: A1STC3
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

357804:PING RS10245
gene id: 357804:PING_RS10245
uniprot id: A1SW77
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxL/LpxM/LpxP family. LpxM subfamily.
messages: Catalyzes the transfer of myristate from myristoyl-acyl carrier protein (ACP) to Kdo(2)-(lauroyl)-lipid IV(A) to form Kdo(2)-lipid A.
messages: Cell inner membrane

357804:PING RS07685
gene id: 357804:PING_RS07685
uniprot id: A1SUW0
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild-type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity.
messages: Belongs to the RecC family.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding.

357804:PING RS04205
gene id: 357804:PING_RS04205
uniprot id: A1ST29
names: Function
names: Similarity
messages: Belongs to the APS kinase family.
messages: Catalyzes the synthesis of activated sulfate.

357804:PING RS01555
gene id: 357804:PING_RS01555
uniprot id: A1SRN8
names: Subcellular Location Annotation
messages: Cytoplasm

357804:PING RS19140
gene id: 357804:PING_RS19140
uniprot id: A1T0X4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

357804:PING RS09415
gene id: 357804:PING_RS09415
uniprot id: A1SVR8
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

357804:PING RS01155
gene id: 357804:PING_RS01155
uniprot id: A1SRH1
names: Function
names: Similarity
messages: Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon.
messages: Belongs to the biotin--protein ligase family.

357804:PING RS00575
gene id: 357804:PING_RS00575
uniprot id: A1SR60
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

357804:PING RS11990
gene id: 357804:PING_RS11990
uniprot id: A1SX52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

357804:PING RS12545
gene id: 357804:PING_RS12545
uniprot id: A1SXE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

357804:PING RS02460
gene id: 357804:PING_RS02460
uniprot id: A1SS61
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell inner membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

357804:PING RS04600
gene id: 357804:PING_RS04600
uniprot id: A1STA1
names: Function
names: Similarity
messages: Belongs to the flavodoxin family.
messages: Low-potential electron donor to a number of redox enzymes.

357804:PING RS05895
gene id: 357804:PING_RS05895
uniprot id: A1STY5
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

357804:PING RS03300
gene id: 357804:PING_RS03300
uniprot id: A1SSL3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell inner membrane
messages: Forms a membrane-associated complex with FtsE.
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in cellular division.

357804:PING RS17660
gene id: 357804:PING_RS17660
uniprot id: A1T036
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

357804:PING RS10085
gene id: 357804:PING_RS10085
uniprot id: A1SW47
names: Subunit
messages: Homodimer.

357804:PING RS02465
gene id: 357804:PING_RS02465
uniprot id: A1SS62
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

357804:PING RS12180
gene id: 357804:PING_RS12180
uniprot id: A1SX86
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

357804:PING RS09480
gene id: 357804:PING_RS09480
uniprot id: A1SVT1
names: Subcellular Location Annotation
messages: Membrane

357804:PING RS17015
gene id: 357804:PING_RS17015
uniprot id: A1SZR9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ZapB family.
messages: Cytoplasm
messages: Homodimer. The ends of the coiled-coil dimer bind to each other, forming polymers. Interacts with FtsZ.
messages: Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA.

357804:PING RS14555
gene id: 357804:PING_RS14555
uniprot id: A1SYG3
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

357804:PING RS01735
gene id: 357804:PING_RS01735
uniprot id: A1SRS3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiJ family.
messages: Cytoplasm
messages: Required for ubiquinone (coenzyme Q) biosynthesis. Binds hydrophobic ubiquinone biosynthetic intermediates via its SCP2 domain and is essential for the stability of the Ubi complex. May constitute a docking platform where Ubi enzymes assemble and access their SCP2-bound polyprenyl substrates.

357804:PING RS03060
gene id: 357804:PING_RS03060
uniprot id: A1SSG6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MsrQ family.
messages: Binds 1 FMN per subunit.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Cell inner membrane
messages: Heterodimer of a catalytic subunit (MsrP) and a heme-binding subunit (MsrQ).
messages: Membrane
messages: Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain.

357804:PING RS00635
gene id: 357804:PING_RS00635
uniprot id: A1SR72
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

357804:PING RS00050
gene id: 357804:PING_RS00050
uniprot id: A1SQW3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

357804:PING RS18765
gene id: 357804:PING_RS18765
uniprot id: A1T0Q7
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Involved in a late step of protoheme IX synthesis.
messages: Membrane

357804:PING RS06085
gene id: 357804:PING_RS06085
uniprot id: A1SU23
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell inner membrane
messages: Self-interacts. Interacts with FtsZ.

357804:PING RS17220
gene id: 357804:PING_RS17220
uniprot id: A1SZV8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

357804:PING RS15920
gene id: 357804:PING_RS15920
uniprot id: A1SZ78
names: Subcellular Location Annotation
messages: Cytoplasm

357804:PING RS00895
gene id: 357804:PING_RS00895
uniprot id: A1SRC0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

357804:PING RS17705
gene id: 357804:PING_RS17705
uniprot id: A1T044
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

357804:PING RS05145
gene id: 357804:PING_RS05145
uniprot id: A1STJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

357804:PING RS11185
gene id: 357804:PING_RS11185
uniprot id: A1SWP3
names: Similarity
names: Subunit
messages: Belongs to the MoaE family.
messages: Heterotetramer of 2 MoaD subunits and 2 MoaE subunits. Also stable as homodimer. The enzyme changes between these two forms during catalysis.

357804:PING RS02650
gene id: 357804:PING_RS02650
uniprot id: A1SS94
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Cell inner membrane
messages: Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system).

357804:PING RS00915
gene id: 357804:PING_RS00915
uniprot id: A1SRC4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell inner membrane
messages: Probably interacts with PlsX.

357804:PING RS18160
gene id: 357804:PING_RS18160
uniprot id: A1T0D3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

357804:PING RS10290
gene id: 357804:PING_RS10290
uniprot id: A1SW86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S49 family.
messages: Cell inner membrane

357804:PING RS00615
gene id: 357804:PING_RS00615
uniprot id: A1SR68
names: Similarity
messages: Belongs to the SCO1/2 family.

357804:PING RS17370
gene id: 357804:PING_RS17370
uniprot id: A1SZY8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

357804:PING RS17070
gene id: 357804:PING_RS17070
uniprot id: A1SZT0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activation of pyruvate formate-lyase 1 under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm

357804:PING RS19355
gene id: 357804:PING_RS19355
uniprot id: A1ST75
names: Similarity
messages: Belongs to the ice-binding protein family.

357804:PING RS17260
gene id: 357804:PING_RS17260
uniprot id: A1SZW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

357804:PING RS12070
gene id: 357804:PING_RS12070
uniprot id: A1SX67
names: Subcellular Location Annotation
messages: Membrane

357804:PING RS00610
gene id: 357804:PING_RS00610
uniprot id: A1SR67
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

357804:PING RS05920
gene id: 357804:PING_RS05920
uniprot id: A1STZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Monomer.

357804:PING RS15210
gene id: 357804:PING_RS15210
uniprot id: A1SYT9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

357804:PING RS03525
gene id: 357804:PING_RS03525
uniprot id: A1SSQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsB family.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

357804:PING RS15480
gene id: 357804:PING_RS15480
uniprot id: A1SYZ1
names: Activity Regulation
names: Caution
names: Domain
names: Function
names: Similarity
messages: Belongs to the GlnD family.
messages: Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism.
messages: Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity.

357804:PING RS04785
gene id: 357804:PING_RS04785
uniprot id: A1STD7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

357804:PING RS03445
gene id: 357804:PING_RS03445
uniprot id: A1SSP2
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

357804:PING RS09790
gene id: 357804:PING_RS09790
uniprot id: A1SVZ0
names: Subcellular Location Annotation
messages: Membrane

357804:PING RS09255
gene id: 357804:PING_RS09255
uniprot id: A1SVN8
names: Similarity
messages: Belongs to the phosphate/phosphite/phosphonate binding protein family.

357804:PING RS13495
gene id: 357804:PING_RS13495
uniprot id: A1SXW8
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

357804:PING RS07745
gene id: 357804:PING_RS07745
uniprot id: A1SUX2
names: Similarity
messages: Belongs to the elongation factor P family.

357804:PING RS08385
gene id: 357804:PING_RS08385
uniprot id: A1SV85
names: Similarity
messages: Belongs to the ribosome association toxin RatA family.

357804:PING RS00875
gene id: 357804:PING_RS00875
uniprot id: A1SRB6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Monomer.

357804:PING RS11940
gene id: 357804:PING_RS11940
uniprot id: A1SX42
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

357804:PING RS03160
gene id: 357804:PING_RS03160
uniprot id: A1SSI6
names: Similarity
messages: Belongs to the SufE family.

357804:PING RS17795
gene id: 357804:PING_RS17795
uniprot id: A1T061
names: Similarity
messages: Belongs to the DsrF/TusC family.

357804:PING RS03630
gene id: 357804:PING_RS03630
uniprot id: A1SSS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane OOP (TC 1.B.6) superfamily. OmpA family.
messages: Cell outer membrane
messages: Membrane

357804:PING RS04870
gene id: 357804:PING_RS04870
uniprot id: A1STF4
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

357804:PING RS14100
gene id: 357804:PING_RS14100
uniprot id: A1SY78
names: Subcellular Location Annotation
messages: Membrane

357804:PING RS00665
gene id: 357804:PING_RS00665
uniprot id: A1SR78
names: Similarity
messages: Belongs to the Nudix hydrolase family.

357804:PING RS03370
gene id: 357804:PING_RS03370
uniprot id: A1SSM7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

357804:PING RS07585
gene id: 357804:PING_RS07585
uniprot id: A1SUT9
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

357804:PING RS18145
gene id: 357804:PING_RS18145
uniprot id: A1T0D0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

357804:PING RS00375
gene id: 357804:PING_RS00375
uniprot id: A1SR24
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

357804:PING RS14005
gene id: 357804:PING_RS14005
uniprot id: A1SY58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF1 family.
messages: Cell membrane

357804:PING RS10890
gene id: 357804:PING_RS10890
uniprot id: A1SWI7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

357804:PING RS01910
gene id: 357804:PING_RS01910
uniprot id: A1SRV5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

357804:PING RS07100
gene id: 357804:PING_RS07100
uniprot id: A1SUK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

357804:PING RS03470
gene id: 357804:PING_RS03470
uniprot id: A1SSP7
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

357804:PING RS05915
gene id: 357804:PING_RS05915
uniprot id: A1STY9
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

357804:PING RS08615
gene id: 357804:PING_RS08615
uniprot id: A1SVC0
names: Subcellular Location Annotation
messages: Membrane

357804:PING RS03380
gene id: 357804:PING_RS03380
uniprot id: A1SSM9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell inner membrane
messages: Cytoplasm
messages: Monomer.

357804:PING RS18155
gene id: 357804:PING_RS18155
uniprot id: A1T0D2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

357804:PING RS06445
gene id: 357804:PING_RS06445
uniprot id: A1SU84
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

357804:PING RS16215
gene id: 357804:PING_RS16215
uniprot id: A1SZC1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

357804:PING RS00630
gene id: 357804:PING_RS00630
uniprot id: A1SR71
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MetA family.
messages: Cytoplasm
messages: Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine.

357804:PING RS12430
gene id: 357804:PING_RS12430
uniprot id: A1SXC5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

357804:PING RS01150
gene id: 357804:PING_RS01150
uniprot id: A1SRH0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

357804:PING RS07180
gene id: 357804:PING_RS07180
uniprot id: A1SUL6
names: Subcellular Location Annotation
messages: Membrane

357804:PING RS13615
gene id: 357804:PING_RS13615
uniprot id: A1SXY7
names: Similarity
messages: Belongs to the pirin family.

357804:PING RS17065
gene id: 357804:PING_RS17065
uniprot id: A1SZS9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycyl radical enzyme (GRE) family. PFL subfamily.
messages: Cytoplasm
messages: Homodimer.

357804:PING RS04685
gene id: 357804:PING_RS04685
uniprot id: A1STB7
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

357804:PING RS07520
gene id: 357804:PING_RS07520
uniprot id: A1SUS7
names: Subcellular Location Annotation
messages: Membrane

357804:PING RS10815
gene id: 357804:PING_RS10815
uniprot id: A1SWH6
names: Similarity
messages: Belongs to the bacterial solute-binding protein 1 family.

357804:PING RS03080
gene id: 357804:PING_RS03080
uniprot id: A1SSH0
names: Function
names: Similarity
messages: Belongs to the HPPK family.
messages: Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.

357804:PING RS04865
gene id: 357804:PING_RS04865
uniprot id: A1STF3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48 family. BepA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Functions as both a chaperone and a metalloprotease. Maintains the integrity of the outer membrane by promoting either the assembly or the elimination of outer membrane proteins, depending on their folding state.
messages: Periplasm

357804:PING RS18050
gene id: 357804:PING_RS18050
uniprot id: A1T0B1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phospholipase A1 family.
messages: Binds 1 Ca(2+) ion per monomer. In the dimeric form the Ca(2+) is bound by different amino acids with binding of each Ca(2+) shared with ligands coming from each monomer. The Ca(2+) ion may have a role in catalysis.
messages: Cell outer membrane
messages: Homodimer; dimerization is reversible, and the dimeric form is the active one.
messages: Hydrolysis of phosphatidylcholine with phospholipase A2 (EC 3.1.1.4) and phospholipase A1 (EC 3.1.1.32) activities.
messages: Membrane

357804:PING RS14595
gene id: 357804:PING_RS14595
uniprot id: A1SYH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

357804:PING RS07920
gene id: 357804:PING_RS07920
uniprot id: A1SV05
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

357804:PING RS08030
gene id: 357804:PING_RS08030
uniprot id: A1SV27
names: Similarity
messages: Belongs to the DEAD box helicase family.

357804:PING RS07500
gene id: 357804:PING_RS07500
uniprot id: A1SUS4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lactate permease family.
messages: Cell inner membrane
messages: Membrane
messages: Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate.

357804:PING RS09800
gene id: 357804:PING_RS09800
uniprot id: A1SVZ2
names: Subcellular Location Annotation
messages: Cytoplasm

357804:PING RS09530
gene id: 357804:PING_RS09530
uniprot id: A1SVU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

357804:PING RS04580
gene id: 357804:PING_RS04580
uniprot id: A1ST97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

357804:PING RS05755
gene id: 357804:PING_RS05755
uniprot id: A1STW0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

357804:PING RS05790
gene id: 357804:PING_RS05790
uniprot id: A1STW7
names: Function
names: Similarity
messages: Belongs to the transglycosylase MltG family.
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

357804:PING RS18950
gene id: 357804:PING_RS18950
uniprot id: A1T0T9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

357804:PING RS08390
gene id: 357804:PING_RS08390
uniprot id: A1SV86
names: Similarity
messages: Belongs to the UPF0125 (RnfH) family.

357804:PING RS05235
gene id: 357804:PING_RS05235
uniprot id: A1STK8
names: Cofactor
names: Similarity
messages: Belongs to the monomeric-type IDH family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

357804:PING RS11195
gene id: 357804:PING_RS11195
uniprot id: A1SWP5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

357804:PING RS15665
gene id: 357804:PING_RS15665
uniprot id: A1SZ28
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

357804:PING RS14080
gene id: 357804:PING_RS14080
uniprot id: A1SY73
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

357804:PING RS05715
gene id: 357804:PING_RS05715
uniprot id: A1STV2
names: Function
names: Similarity
names: Subunit
messages: ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.
messages: Belongs to the ParA family. MinD subfamily.
messages: Interacts with MinC and FtsZ.

357804:PING RS00425
gene id: 357804:PING_RS00425
uniprot id: A1SR30
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).

357804:PING RS18140
gene id: 357804:PING_RS18140
uniprot id: A1T0C9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

357804:PING RS00385
gene id: 357804:PING_RS00385
uniprot id: A1SR26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RseB family.
messages: Periplasm

357804:PING RS00965
gene id: 357804:PING_RS00965
uniprot id: A1SRD4
names: Similarity
messages: Belongs to the UPF0111 family.

357804:PING RS16870
gene id: 357804:PING_RS16870
uniprot id: A1SZP5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell inner membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

357804:PING RS07025
gene id: 357804:PING_RS07025
uniprot id: A1SUI5
names: Function
names: Similarity
messages: A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.
messages: Belongs to the NifU family.

357804:PING RS00985
gene id: 357804:PING_RS00985
uniprot id: A1SRD8
names: Similarity
messages: Belongs to the PspA/IM30 family.

357804:PING RS14810
gene id: 357804:PING_RS14810
uniprot id: A1SYL3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b family.
messages: Binds 2 heme groups non-covalently.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

357804:PING RS18730
gene id: 357804:PING_RS18730
uniprot id: A1T0Q0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0394 family.
messages: Membrane

357804:PING RS14590
gene id: 357804:PING_RS14590
uniprot id: A1SYH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

357804:PING RS00920
gene id: 357804:PING_RS00920
uniprot id: A1SRC5
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

357804:PING RS18095
gene id: 357804:PING_RS18095
uniprot id: A1SXW5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

357804:PING RS03320
gene id: 357804:PING_RS03320
uniprot id: A1SSL7
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

357804:PING RS05855
gene id: 357804:PING_RS05855
uniprot id: A1STX8
names: Similarity
messages: Belongs to the asparagine synthetase family.

357804:PING RS16860
gene id: 357804:PING_RS16860
uniprot id: A1SZP3
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

357804:PING RS02815
gene id: 357804:PING_RS02815
uniprot id: A1SSC5
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

357804:PING RS16370
gene id: 357804:PING_RS16370
uniprot id: A1SZF2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Cytoplasm
messages: Homodimer.

357804:PING RS06190
gene id: 357804:PING_RS06190
uniprot id: A1SU42
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamB family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

357804:PING RS04235
gene id: 357804:PING_RS04235
uniprot id: A1ST34
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

357804:PING RS19625
gene id: 357804:PING_RS19625
uniprot id: A1SZM3
names: Similarity
messages: Belongs to the ice-binding protein family.

357804:PING RS02670
gene id: 357804:PING_RS02670
uniprot id: A1SS98
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.

357804:PING RS06185
gene id: 357804:PING_RS06185
uniprot id: A1SU41
names: Similarity
messages: Belongs to the YfgM family.

357804:PING RS05555
gene id: 357804:PING_RS05555
uniprot id: A1STS0
names: Function
names: Similarity
messages: Belongs to the Ap4A hydrolase family.
messages: Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.

357804:PING RS19470
gene id: 357804:PING_RS19470
uniprot id: A1SVP7
names: Similarity
messages: Belongs to the ice-binding protein family.

357804:PING RS00380
gene id: 357804:PING_RS00380
uniprot id: A1SR25
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E.
messages: Belongs to the RseA family.
messages: Cell inner membrane
messages: Interacts 1:1 with ECF RNA polymerase sigma-E (RpoE); this inhibits the interaction of sigma-E with the RNA polymerase catalytic core and leads to a decreased expression of sigma-E-regulated genes. Interacts with RseB.

357804:PING RS05470
gene id: 357804:PING_RS05470
uniprot id: A1STQ4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urocanase family.
messages: Binds 1 NAD(+) per subunit.
messages: Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

357804:PING RS09295
gene id: 357804:PING_RS09295
uniprot id: A1SVP4
names: Similarity
messages: Belongs to the peptidase M18 family.

357804:PING RS07420
gene id: 357804:PING_RS07420
uniprot id: A1SUQ8
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 2 residues (Tyr-58 and Arg-61) present in a large hydrophobic pocket are probably involved in substrate specificity. They are important for desuccinylation activity, but dispensable for deacetylation activity.
messages: Belongs to the sirtuin family. Class III subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form.

357804:PING RS16710
gene id: 357804:PING_RS16710
uniprot id: A1SZL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

357804:PING RS11580
gene id: 357804:PING_RS11580
uniprot id: A1SWX2
names: Subunit
messages: Homodimer.

357804:PING RS15645
gene id: 357804:PING_RS15645
uniprot id: A1SZ24
names: Similarity
messages: Belongs to the UPF0246 family.

357804:PING RS11220
gene id: 357804:PING_RS11220
uniprot id: A1SWQ0
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.
messages: Binds 1 [4Fe-4S] cluster.
messages: Binds 1 molybdenum-bis(molybdopterin guanine dinucleotide) (Mo-bis-MGD) cofactor per subunit.
messages: Catalytic subunit of the periplasmic nitrate reductase complex NapAB. Receives electrons from NapB and catalyzes the reduction of nitrate to nitrite.
messages: Component of the periplasmic nitrate reductase NapAB complex composed of NapA and NapB.
messages: Periplasm
messages: Predicted to be exported by the Tat system. The position of the signal peptide cleavage has not been experimentally proven.

357804:PING RS11245
gene id: 357804:PING_RS11245
uniprot id: A1SWQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

357804:PING RS08485
gene id: 357804:PING_RS08485
uniprot id: A1SVA5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.

357804:PING RS05940
gene id: 357804:PING_RS05940
uniprot id: A1STZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

357804:PING RS01195
gene id: 357804:PING_RS01195
uniprot id: A1SRH6
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Catalyzes the phosphorylation of D-xylulose to D-xylulose 5-phosphate.

357804:PING RS04290
gene id: 357804:PING_RS04290
uniprot id: A1ST44
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

357804:PING RS03935
gene id: 357804:PING_RS03935
uniprot id: A1SSY4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell inner membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

357804:PING RS17990
gene id: 357804:PING_RS17990
uniprot id: A1T099
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

357804:PING RS11745
gene id: 357804:PING_RS11745
uniprot id: A1SX04
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

357804:PING RS00150
gene id: 357804:PING_RS00150
uniprot id: A1SQY3
names: Similarity
messages: Belongs to the VgrG protein family.

357804:PING RS04560
gene id: 357804:PING_RS04560
uniprot id: A1ST93
names: Subcellular Location Annotation
messages: Membrane

357804:PING RS15515
gene id: 357804:PING_RS15515
uniprot id: A1SYZ8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LapA family.
messages: Cell inner membrane
messages: Involved in the assembly of lipopolysaccharide (LPS).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

357804:PING RS01620
gene id: 357804:PING_RS01620
uniprot id: A1SRQ1
names: Function
names: Similarity
messages: In the C-terminal section; belongs to the aldehyde dehydrogenase family.
messages: In the N-terminal section; belongs to the proline dehydrogenase family.
messages: Oxidizes proline to glutamate for use as a carbon and nitrogen source.

357804:PING RS03185
gene id: 357804:PING_RS03185
uniprot id: A1SSJ1
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

357804:PING RS09735
gene id: 357804:PING_RS09735
uniprot id: A1SVX9
names: Similarity
messages: Belongs to the citrate synthase family.

357804:PING RS11545
gene id: 357804:PING_RS11545
uniprot id: A1SWW7
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

357804:PING RS19255
gene id: 357804:PING_RS19255
uniprot id: A1T0Z6
names: Subcellular Location Annotation
messages: Membrane

357804:PING RS11240
gene id: 357804:PING_RS11240
uniprot id: A1SWQ4
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the helicase family. DinG subfamily. Type 1 sub-subfamily.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA-dependent ATPase and 5'-3' DNA helicase.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

357804:PING RS08035
gene id: 357804:PING_RS08035
uniprot id: A1SV28
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

357804:PING RS03475
gene id: 357804:PING_RS03475
uniprot id: A1SSP8
names: Function
names: Similarity
messages: Belongs to the phenylacetyl-CoA ligase family.
messages: Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).

357804:PING RS05880
gene id: 357804:PING_RS05880
uniprot id: A1STY2
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.

357804:PING RS10205
gene id: 357804:PING_RS10205
uniprot id: A1SW69
names: Subcellular Location Annotation
messages: Membrane

357804:PING RS00900
gene id: 357804:PING_RS00900
uniprot id: A1SRC1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

357804:PING RS01050
gene id: 357804:PING_RS01050
uniprot id: A1SRF1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HemG family.
messages: Binds 1 FMN non-covalently per subunit.
messages: Catalyzes the 6-electron oxidation of protoporphyrinogen IX to form protoporphyrin IX; under anaerobic conditions uses menaquinone as an electron acceptor, under aerobic conditions uses ubiquinone as an electron acceptor.
messages: Cell inner membrane

357804:PING RS09835
gene id: 357804:PING_RS09835
uniprot id: A1SVZ9
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

357804:PING RS12825
gene id: 357804:PING_RS12825
uniprot id: A1SXK0
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

357804:PING RS09840
gene id: 357804:PING_RS09840
uniprot id: A1SW00
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

357804:PING RS10135
gene id: 357804:PING_RS10135
uniprot id: A1SW57
names: Subcellular Location Annotation
messages: Cytoplasm

357804:PING RS17860
gene id: 357804:PING_RS17860
uniprot id: A1T074
names: Similarity
messages: Belongs to the polysaccharide synthase family.

357804:PING RS11635
gene id: 357804:PING_RS11635
uniprot id: A1SWY3
names: Similarity
messages: Belongs to the citrate synthase family.

357804:PING RS18635
gene id: 357804:PING_RS18635
uniprot id: A1T0N0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.

357804:PING RS14245
gene id: 357804:PING_RS14245
uniprot id: A1SYA4
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.

357804:PING RS04745
gene id: 357804:PING_RS04745
uniprot id: A1STC9
names: Similarity
messages: Belongs to the UPF0434 family.

357804:PING RS08005
gene id: 357804:PING_RS08005
uniprot id: A1SV21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0114 family.
messages: Cell membrane
messages: Membrane

357804:PING RS12600
gene id: 357804:PING_RS12600
uniprot id: A1SXF9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M20A family. DapE subfamily.
messages: Binds 2 Zn(2+) or Co(2+) ions per subunit.
messages: Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
messages: Homodimer.

357804:PING RS02700
gene id: 357804:PING_RS02700
uniprot id: A1SSA3
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

357804:PING RS11640
gene id: 357804:PING_RS11640
uniprot id: A1SWY4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

357804:PING RS08395
gene id: 357804:PING_RS08395
uniprot id: A1SV87
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamE family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

357804:PING RS13500
gene id: 357804:PING_RS13500
uniprot id: A1SXW9
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

357804:PING RS17895
gene id: 357804:PING_RS17895
uniprot id: A1T080
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

357804:PING RS15295
gene id: 357804:PING_RS15295
uniprot id: A1SYV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

357804:PING RS05760
gene id: 357804:PING_RS05760
uniprot id: A1STW1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

357804:PING RS15250
gene id: 357804:PING_RS15250
uniprot id: A1SYU7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

357804:PING RS02780
gene id: 357804:PING_RS02780
uniprot id: A1SSB8
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily.
messages: Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA.

357804:PING RS03505
gene id: 357804:PING_RS03505
uniprot id: A1SSQ4
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

357804:PING RS18470
gene id: 357804:PING_RS18470
uniprot id: A1T0J6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

357804:PING RS03770
gene id: 357804:PING_RS03770
uniprot id: A1SSV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

357804:PING RS06760
gene id: 357804:PING_RS06760
uniprot id: A1SUE3
names: Function
messages: Acts as a radical domain for damaged PFL and possibly other radical proteins.

357804:PING RS02080
gene id: 357804:PING_RS02080
uniprot id: A1SRY6
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.

357804:PING RS17145
gene id: 357804:PING_RS17145
uniprot id: A1SZU6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

357804:PING RS13475
gene id: 357804:PING_RS13475
uniprot id: A1SXW4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

357804:PING RS03880
gene id: 357804:PING_RS03880
uniprot id: A1SSX3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

357804:PING RS07440
gene id: 357804:PING_RS07440
uniprot id: A1SUR2
names: Function
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.
messages: Specifically catalyzes the dephosphorylation of 2-phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress.

357804:PING RS15430
gene id: 357804:PING_RS15430
uniprot id: A1SYY2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UreE family.
messages: Cytoplasm
messages: Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly.

357804:PING RS02435
gene id: 357804:PING_RS02435
uniprot id: A1SS56
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

357804:PING RS17505
gene id: 357804:PING_RS17505
uniprot id: A1T011
names: Subcellular Location Annotation
messages: Membrane

357804:PING RS15220
gene id: 357804:PING_RS15220
uniprot id: A1SYU1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Crl family.
messages: Binds to the sigma-S subunit of RNA polymerase, activating expression of sigma-S-regulated genes. Stimulates RNA polymerase holoenzyme formation and may bind to several other sigma factors, such as sigma-70 and sigma-32.
messages: Cytoplasm

357804:PING RS06785
gene id: 357804:PING_RS06785
uniprot id: A1SUE8
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

357804:PING RS17060
gene id: 357804:PING_RS17060
uniprot id: A1SZS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FNT transporter (TC 2.A.44) family.
messages: Membrane

357804:PING RS14440
gene id: 357804:PING_RS14440
uniprot id: A1SYE0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. HflK subfamily.
messages: HflC and HflK could encode or regulate a protease.
messages: HflC and HflK may interact to form a multimeric complex.
messages: Membrane

357804:PING RS14650
gene id: 357804:PING_RS14650
uniprot id: A1SYI2
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

357804:PING RS05350
gene id: 357804:PING_RS05350
uniprot id: A1STN1
names: Similarity
messages: Belongs to the glutamate synthase family.

357804:PING RS18135
gene id: 357804:PING_RS18135
uniprot id: A1T0C8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

357804:PING RS12050
gene id: 357804:PING_RS12050
uniprot id: A1SX63
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CysZ family.
messages: Cell inner membrane
messages: High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway.

357804:PING RS02640
gene id: 357804:PING_RS02640
uniprot id: A1SS92
names: Function
names: Similarity
messages: Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
messages: Belongs to the Nudix hydrolase family. RppH subfamily.

357804:PING RS16840
gene id: 357804:PING_RS16840
uniprot id: A1SZN9
names: Similarity
messages: Belongs to the P(II) protein family.

357804:PING RS05745
gene id: 357804:PING_RS05745
uniprot id: A1STV8
names: Function
names: Similarity
messages: Belongs to the DUF177 domain family.
messages: Plays a role in synthesis, processing and/or stability of 23S rRNA.

357804:PING RS15620
gene id: 357804:PING_RS15620
uniprot id: A1SZ19
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methyltransferase superfamily. RsmC family.
messages: Cytoplasm
messages: Monomer.
messages: Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle.

357804:PING RS11500
gene id: 357804:PING_RS11500
uniprot id: A1SWV8
names: Function
messages: This protein is a positive regulator for the phosphate regulon. Transcription of this operon is positively regulated by PhoB and PhoR when phosphate is limited.

357804:PING RS11680
gene id: 357804:PING_RS11680
uniprot id: A1SWZ2
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.

357804:PING RS19110
gene id: 357804:PING_RS19110
uniprot id: A1T0W8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

357804:PING RS15315
gene id: 357804:PING_RS15315
uniprot id: A1SYW0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

357804:PING RS03775
gene id: 357804:PING_RS03775
uniprot id: A1SSV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

357804:PING RS06070
gene id: 357804:PING_RS06070
uniprot id: A1SU20
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

357804:PING RS15425
gene id: 357804:PING_RS15425
uniprot id: A1SYY1
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
messages: Binds 2 nickel ions per subunit.
messages: Carboxylation allows a single lysine to coordinate two nickel ions.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

357804:PING RS01885
gene id: 357804:PING_RS01885
uniprot id: A1SRV2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TPP enzyme family. MenD subfamily.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
messages: Homodimer.

357804:PING RS00360
gene id: 357804:PING_RS00360
uniprot id: A1SR22
names: Similarity
messages: Belongs to the SdhE FAD assembly factor family.

357804:PING RS17980
gene id: 357804:PING_RS17980
uniprot id: A1T097
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

357804:PING RS02760
gene id: 357804:PING_RS02760
uniprot id: A1SSB4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

357804:PING RS03605
gene id: 357804:PING_RS03605
uniprot id: A1SSS3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.

357804:PING RS18540
gene id: 357804:PING_RS18540
uniprot id: A1T0L0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliN/MopA/SpaO family.
messages: Cell membrane
messages: FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

357804:PING RS16820
gene id: 357804:PING_RS16820
uniprot id: A1SZN5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

357804:PING RS08220
gene id: 357804:PING_RS08220
uniprot id: A1SV57
names: Similarity
messages: Belongs to the Gfa family.

357804:PING RS01575
gene id: 357804:PING_RS01575
uniprot id: A1SRP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

357804:PING RS11685
gene id: 357804:PING_RS11685
uniprot id: A1SWZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YejK family.
messages: nucleoid

357804:PING RS05575
gene id: 357804:PING_RS05575
uniprot id: A1STS4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptD family.
messages: Cell outer membrane
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptE and LptA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.

357804:PING RS09970
gene id: 357804:PING_RS09970
uniprot id: A1SW25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

357804:PING RS02570
gene id: 357804:PING_RS02570
uniprot id: A1SS83
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

357804:PING RS02810
gene id: 357804:PING_RS02810
uniprot id: A1SSC4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

357804:PING RS00870
gene id: 357804:PING_RS00870
uniprot id: A1SRB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial secretin family.
messages: Cell outer membrane
messages: Membrane

357804:PING RS02075
gene id: 357804:PING_RS02075
uniprot id: A1SRY5
names: Similarity
messages: Belongs to the UPF0270 family.

357804:PING RS06410
gene id: 357804:PING_RS06410
uniprot id: A1SU77
names: Similarity
messages: Belongs to the HypE family.

357804:PING RS06215
gene id: 357804:PING_RS06215
uniprot id: A1SU47
names: Similarity
messages: Belongs to the UPF0102 family.

357804:PING RS02930
gene id: 357804:PING_RS02930
uniprot id: A1SSE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family.
messages: Periplasm

357804:PING RS04760
gene id: 357804:PING_RS04760
uniprot id: A1STD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0719 family.
messages: Membrane

357804:PING RS17950
gene id: 357804:PING_RS17950
uniprot id: A1T091
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. UvrD subfamily.
messages: Homodimer.
messages: Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replication; it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction.

357804:PING RS00585
gene id: 357804:PING_RS00585
uniprot id: A1SR62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP J family.
messages: Cell inner membrane
messages: Membrane

357804:PING RS16845
gene id: 357804:PING_RS16845
uniprot id: A1SZP0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

357804:PING RS12660
gene id: 357804:PING_RS12660
uniprot id: A1SXH1
names: Subcellular Location Annotation
messages: Membrane

357804:PING RS11655
gene id: 357804:PING_RS11655
uniprot id: A1SWY7
names: Similarity
messages: Belongs to the UPF0234 family.

357804:PING RS01210
gene id: 357804:PING_RS01210
uniprot id: A1SRH9
names: Similarity
messages: Belongs to the peptidase M20A family. ArgE subfamily.

357804:PING RS15290
gene id: 357804:PING_RS15290
uniprot id: A1SYV5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamA family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

357804:PING RS04420
gene id: 357804:PING_RS04420
uniprot id: A1ST66
names: Similarity
messages: Belongs to the DEAD box helicase family.

357804:PING RS15555
gene id: 357804:PING_RS15555
uniprot id: A1SZ06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
messages: Cell inner membrane
messages: Membrane

357804:PING RS08730
gene id: 357804:PING_RS08730
uniprot id: A1SVE4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.

357804:PING RS17090
gene id: 357804:PING_RS17090
uniprot id: A1SZT4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Homohexamer.
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the CobB/CobQ family.
messages: Involved in acetate metabolism.
messages: The N-terminal region seems to be important for proper quaternary structure. The C-terminal region contains the substrate-binding site.

357804:PING RS05165
gene id: 357804:PING_RS05165
uniprot id: A1STJ4
names: Subcellular Location Annotation
messages: Membrane

357804:PING RS19535
gene id: 357804:PING_RS19535
uniprot id: A1SWL9
names: Subcellular Location Annotation
messages: Membrane

357804:PING RS02665
gene id: 357804:PING_RS02665
uniprot id: A1SS97
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

357804:PING RS06805
gene id: 357804:PING_RS06805
uniprot id: A1SUF2
names: Similarity
messages: Belongs to the ThrE exporter (TC 2.A.79) family.

357804:PING RS05175
gene id: 357804:PING_RS05175
uniprot id: A1STJ6
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

357804:PING RS12410
gene id: 357804:PING_RS12410
uniprot id: A1SXC1
names: Similarity
messages: Belongs to the MYG1 family.

357804:PING RS12095
gene id: 357804:PING_RS12095
uniprot id: A1SX72
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

357804:PING RS05660
gene id: 357804:PING_RS05660
uniprot id: A1STU1
names: Subcellular Location Annotation
messages: Membrane

357804:PING RS13375
gene id: 357804:PING_RS13375
uniprot id: A1SXU4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

357804:PING RS04275
gene id: 357804:PING_RS04275
uniprot id: A1ST42
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

357804:PING RS01190
gene id: 357804:PING_RS01190
uniprot id: A1SRH5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

357804:PING RS08735
gene id: 357804:PING_RS08735
uniprot id: A1SVE5
names: Subcellular Location Annotation
messages: Membrane

357804:PING RS16680
gene id: 357804:PING_RS16680
uniprot id: A1SZK8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. HflK subfamily.
messages: HflC and HflK could encode or regulate a protease.
messages: HflC and HflK may interact to form a multimeric complex.
messages: Membrane

357804:PING RS05585
gene id: 357804:PING_RS05585
uniprot id: A1STS6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type 2 tetrahydrodipicolinate N-succinyltransferase family.
messages: Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA.
messages: Cytoplasm
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

357804:PING RS18085
gene id: 357804:PING_RS18085
uniprot id: A1T0B8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

357804:PING RS01690
gene id: 357804:PING_RS01690
uniprot id: A1SRR4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

357804:PING RS10445
gene id: 357804:PING_RS10445
uniprot id: A1SWB3
names: Similarity
messages: Belongs to the glycosyl hydrolase.

357804:PING RS04570
gene id: 357804:PING_RS04570
uniprot id: A1ST95
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

357804:PING RS09830
gene id: 357804:PING_RS09830
uniprot id: A1SVZ8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

357804:PING RS14010
gene id: 357804:PING_RS14010
uniprot id: A1SY59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

357804:PING RS04300
gene id: 357804:PING_RS04300
uniprot id: A1ST46
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

357804:PING RS18845
gene id: 357804:PING_RS18845
uniprot id: A1T0S2
names: Similarity
messages: Belongs to the fabD family.

357804:PING RS09875
gene id: 357804:PING_RS09875
uniprot id: A1SW07
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

357804:PING RS15330
gene id: 357804:PING_RS15330
uniprot id: A1SYW3
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

357804:PING RS17510
gene id: 357804:PING_RS17510
uniprot id: A1T012
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

357804:PING RS19200
gene id: 357804:PING_RS19200
uniprot id: A1T0Y5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

357804:PING RS00505
gene id: 357804:PING_RS00505
uniprot id: A1SR46
names: Similarity
messages: Belongs to the SorC transcriptional regulatory family.

357804:PING RS17685
gene id: 357804:PING_RS17685
uniprot id: A1T041
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

357804:PING RS03405
gene id: 357804:PING_RS03405
uniprot id: A1SSN4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

357804:PING RS01675
gene id: 357804:PING_RS01675
uniprot id: A1SRR1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

357804:PING RS16415
gene id: 357804:PING_RS16415
uniprot id: A1SZG1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UbiD family.
messages: Binds 1 prenylated FMN (prenyl-FMN) per subunit.
messages: Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis.
messages: Cell membrane
messages: Homohexamer.

357804:PING RS16865
gene id: 357804:PING_RS16865
uniprot id: A1SZP4
names: Function
names: Similarity
messages: Belongs to the ribF family.
messages: Catalyzes the phosphorylation of riboflavin to FMN followed by the adenylation of FMN to FAD.

357804:PING RS02090
gene id: 357804:PING_RS02090
uniprot id: A1SRY8
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

357804:PING RS08295
gene id: 357804:PING_RS08295
uniprot id: A1SV69
names: Similarity
messages: In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.
messages: In the central section; belongs to the CRISPR-associated helicase Cas3 family.

357804:PING RS05725
gene id: 357804:PING_RS05725
uniprot id: A1STV4
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

357804:PING RS02205
gene id: 357804:PING_RS02205
uniprot id: A1SS10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

357804:PING RS17120
gene id: 357804:PING_RS17120
uniprot id: A1SZU0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: In the N-terminal section; belongs to the FGAMS family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.

357804:PING RS05680
gene id: 357804:PING_RS05680
uniprot id: A1STU5
names: Similarity
messages: Belongs to the DnaA family.

357804:PING RS18270
gene id: 357804:PING_RS18270
uniprot id: A1T0F5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

357804:PING RS06560
gene id: 357804:PING_RS06560
uniprot id: A1SUA5
names: Subcellular Location Annotation
messages: Membrane

357804:PING RS09960
gene id: 357804:PING_RS09960
uniprot id: A1SW23
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane
messages: Membrane

357804:PING RS04555
gene id: 357804:PING_RS04555
uniprot id: A1ST92
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

357804:PING RS16720
gene id: 357804:PING_RS16720
uniprot id: A1SZL6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueG family.
messages: Binds 2 [4Fe-4S] clusters per monomer.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

357804:PING RS10955
gene id: 357804:PING_RS10955
uniprot id: A1SWK0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.

357804:PING RS04825
gene id: 357804:PING_RS04825
uniprot id: A1STE5
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

357804:PING RS17735
gene id: 357804:PING_RS17735
uniprot id: A1T050
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

357804:PING RS12585
gene id: 357804:PING_RS12585
uniprot id: A1SXF6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

357804:PING RS02515
gene id: 357804:PING_RS02515
uniprot id: A1SS72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP E family.
messages: Cytoplasm

357804:PING RS03555
gene id: 357804:PING_RS03555
uniprot id: A1SSR5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoS subfamily.
messages: Cytoplasm
messages: Interacts with the RNA polymerase core enzyme.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the master transcriptional regulator of the stationary phase and the general stress response.

357804:PING RS11625
gene id: 357804:PING_RS11625
uniprot id: A1SWY1
names: Cofactor
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: The heme is bound between the two transmembrane subunits.

357804:PING RS14205
gene id: 357804:PING_RS14205
uniprot id: A1SY96
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

357804:PING RS01600
gene id: 357804:PING_RS01600
uniprot id: A1SRP7
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

357804:PING RS19025
gene id: 357804:PING_RS19025
uniprot id: A1T0V1
names: Function
names: Similarity
messages: Belongs to the PhnJ family.
messages: Catalyzes the breakage of the C-P bond in alpha-D-ribose 1-methylphosphonate 5-phosphate (PRPn) forming alpha-D-ribose.

357804:PING RS05095
gene id: 357804:PING_RS05095
uniprot id: A1STI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

357804:PING RS06665
gene id: 357804:PING_RS06665
uniprot id: A1SUC6
names: Function
names: Similarity
messages: Belongs to the gas vesicle protein type A family.
messages: Gas vesicles are small, hollow, gas filled protein structures that are found in several microbial planktonic microorganisms. They allow the positioning of the organism at the favorable depth for growth.

357804:PING RS01045
gene id: 357804:PING_RS01045
uniprot id: A1SRF0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrkH potassium transport family.
messages: Cell inner membrane
messages: Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA.
messages: Membrane

357804:PING RS01920
gene id: 357804:PING_RS01920
uniprot id: A1SRV8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).

357804:PING RS03920
gene id: 357804:PING_RS03920
uniprot id: A1SSY1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

357804:PING RS02645
gene id: 357804:PING_RS02645
uniprot id: A1SS93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm

357804:PING RS03810
gene id: 357804:PING_RS03810
uniprot id: A1SSW5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Pal lipoprotein family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

357804:PING RS14200
gene id: 357804:PING_RS14200
uniprot id: A1SY95
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

357804:PING RS00940
gene id: 357804:PING_RS00940
uniprot id: A1SRC9
names: Cofactor
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A single active site specifically recognizes both ATP and CTP and is responsible for their addition.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 1 subfamily.
messages: Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases.
messages: Comprises two domains: an N-terminal domain containing the nucleotidyltransferase activity and a C-terminal HD domain associated with both phosphodiesterase and phosphatase activities.
messages: Magnesium is required for nucleotidyltransferase activity.
messages: Monomer. Can also form homodimers and oligomers.
messages: Nickel for phosphatase activity.

357804:PING RS03890
gene id: 357804:PING_RS03890
uniprot id: A1SSX5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

357804:PING RS15625
gene id: 357804:PING_RS15625
uniprot id: A1SZ20
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.

357804:PING RS17225
gene id: 357804:PING_RS17225
uniprot id: A1SZV9
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The autoendoproteolytic cleavage occurs by a canonical serine protease mechanism, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. During this reaction, the Ser that is part of the protease active site of the proenzyme becomes the pyruvoyl prosthetic group, which constitutes an essential element of the active site of the mature decarboxylase.

357804:PING RS02655
gene id: 357804:PING_RS02655
uniprot id: A1SS95
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell inner membrane

357804:PING RS15320
gene id: 357804:PING_RS15320
uniprot id: A1SYW1
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by GTP. Inhibited by UTP.
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.

357804:PING RS02660
gene id: 357804:PING_RS02660
uniprot id: A1SS96
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

357804:PING RS18510
gene id: 357804:PING_RS18510
uniprot id: A1T0K4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum
messages: Belongs to the FliD family.
messages: Homopentamer.
messages: Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Secreted

357804:PING RS17150
gene id: 357804:PING_RS17150
uniprot id: A1SZU7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Plays an essential role in type IV pili and type II pseudopili formation by proteolytically removing the leader sequence from substrate proteins and subsequently monomethylating the alpha-amino group of the newly exposed N-terminal phenylalanine.

357804:PING RS01055
gene id: 357804:PING_RS01055
uniprot id: A1SRF2
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

357804:PING RS09955
gene id: 357804:PING_RS09955
uniprot id: A1SW22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TamA family.
messages: Cell outer membrane
messages: Membrane

357804:PING RS00750
gene id: 357804:PING_RS00750
uniprot id: A1SR92
names: Function
names: Similarity
messages: Belongs to the mannonate dehydratase family.
messages: Catalyzes the dehydration of D-mannonate.

357804:PING RS18465
gene id: 357804:PING_RS18465
uniprot id: A1T0J5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

357804:PING RS04720
gene id: 357804:PING_RS04720
uniprot id: A1STC4
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

357804:PING RS18460
gene id: 357804:PING_RS18460
uniprot id: A1T0J4
names: Function
names: Similarity
messages: Belongs to the FlgD family.
messages: Required for flagellar hook formation. May act as a scaffolding protein.

357804:PING RS12075
gene id: 357804:PING_RS12075
uniprot id: A1SX68
names: Similarity
messages: Belongs to the peptidase M1 family.

357804:PING RS08690
gene id: 357804:PING_RS08690
uniprot id: A1SVD5
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Feedback inhibited by histidine.

357804:PING RS18090
gene id: 357804:PING_RS18090
uniprot id: A1SXW6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

357804:PING RS00315
gene id: 357804:PING_RS00315
uniprot id: A1SR13
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

357804:PING RS18515
gene id: 357804:PING_RS18515
uniprot id: A1T0K5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

357804:PING RS03260
gene id: 357804:PING_RS03260
uniprot id: A1SSK5
names: Similarity
messages: Belongs to the SIS family. GutQ/KpsF subfamily.

357804:PING RS07590
gene id: 357804:PING_RS07590
uniprot id: A1SUU0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.

357804:PING RS08710
gene id: 357804:PING_RS08710
uniprot id: A1SVE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Membrane

357804:PING RS17350
gene id: 357804:PING_RS17350
uniprot id: A1SZY4
names: Subcellular Location Annotation
messages: Cell inner membrane

357804:PING RS08585
gene id: 357804:PING_RS08585
uniprot id: A1SVB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Cell inner membrane
messages: Membrane

357804:PING RS14700
gene id: 357804:PING_RS14700
uniprot id: A1SYJ1
names: Similarity
messages: Belongs to the ice-binding protein family.

357804:PING RS03665
gene id: 357804:PING_RS03665
uniprot id: A1SST5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cx-SAM synthase family.
messages: Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM).
messages: Homodimer.

357804:PING RS17140
gene id: 357804:PING_RS17140
uniprot id: A1SZU5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

357804:PING RS07910
gene id: 357804:PING_RS07910
uniprot id: A1SV03
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.

357804:PING RS06075
gene id: 357804:PING_RS06075
uniprot id: A1SU21
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

357804:PING RS16995
gene id: 357804:PING_RS16995
uniprot id: A1SZR5
names: Similarity
messages: Belongs to the peptidase S13 family.

357804:PING RS13510
gene id: 357804:PING_RS13510
uniprot id: A1SXX1
names: Similarity
messages: Belongs to the citrate synthase family.

357804:PING RS17770
gene id: 357804:PING_RS17770
uniprot id: A1T056
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

357804:PING RS01745
gene id: 357804:PING_RS01745
uniprot id: A1SRS5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

357804:PING RS13575
gene id: 357804:PING_RS13575
uniprot id: A1SXY1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell inner membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

357804:PING RS17155
gene id: 357804:PING_RS17155
uniprot id: A1SZU8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

357804:PING RS03670
gene id: 357804:PING_RS03670
uniprot id: A1SST6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.

357804:PING RS03515
gene id: 357804:PING_RS03515
uniprot id: A1SSQ7
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

357804:PING RS13930
gene id: 357804:PING_RS13930
uniprot id: A1SY43
names: Subcellular Location Annotation
messages: Cytoplasm

357804:PING RS17820
gene id: 357804:PING_RS17820
uniprot id: A1T066
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

357804:PING RS07795
gene id: 357804:PING_RS07795
uniprot id: A1SUY1
names: Function
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

357804:PING RS04950
gene id: 357804:PING_RS04950
uniprot id: A1STG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

357804:PING RS18045
gene id: 357804:PING_RS18045
uniprot id: A1T0B0
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

357804:PING RS04265
gene id: 357804:PING_RS04265
uniprot id: A1ST40
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

357804:PING RS12550
gene id: 357804:PING_RS12550
uniprot id: A1SXE9
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

357804:PING RS09140
gene id: 357804:PING_RS09140
uniprot id: A1SVL7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gas vesicle protein type A family.
messages: Gas vesicles are small, hollow, gas filled protein structures that are found in several microbial planktonic microorganisms. They allow the positioning of the organism at the favorable depth for growth. GvpA type proteins form the essential core of the structure.
messages: gas vesicle membrane

357804:PING RS03925
gene id: 357804:PING_RS03925
uniprot id: A1SSY2
names: Similarity
messages: Belongs to the BolA/IbaG family.

357804:PING RS16110
gene id: 357804:PING_RS16110
uniprot id: A1SZB0
names: Similarity
messages: Belongs to the adrenodoxin/putidaredoxin family.

357804:PING RS15520
gene id: 357804:PING_RS15520
uniprot id: A1SYZ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

357804:PING RS08720
gene id: 357804:PING_RS08720
uniprot id: A1SVE2
names: Function
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.
messages: DNA-dependent ATPase that plays important roles in cellular responses to stalled DNA replication processes.

357804:PING RS06530
gene id: 357804:PING_RS06530
uniprot id: A1SU99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

357804:PING RS05775
gene id: 357804:PING_RS05775
uniprot id: A1STW4
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

357804:PING RS11525
gene id: 357804:PING_RS11525
uniprot id: A1SWW3
names: Similarity
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.

357804:PING RS02295
gene id: 357804:PING_RS02295
uniprot id: A1SS29
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

357804:PING RS18395
gene id: 357804:PING_RS18395
uniprot id: A1T0I1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliH family.
messages: Cytoplasm
messages: Needed for flagellar regrowth and assembly.

357804:PING RS13490
gene id: 357804:PING_RS13490
uniprot id: A1SXW7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

357804:PING RS11620
gene id: 357804:PING_RS11620
uniprot id: A1SWY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Cell inner membrane
messages: Membrane

357804:PING RS14225
gene id: 357804:PING_RS14225
uniprot id: A1SYA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC41A transporter family.
messages: Membrane

357804:PING RS16530
gene id: 357804:PING_RS16530
uniprot id: A1SZH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

357804:PING RS04295
gene id: 357804:PING_RS04295
uniprot id: A1ST45
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

357804:PING RS03130
gene id: 357804:PING_RS03130
uniprot id: A1SSI0
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

357804:PING RS11615
gene id: 357804:PING_RS11615
uniprot id: A1SWX9
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

357804:PING RS14975
gene id: 357804:PING_RS14975
uniprot id: A1SYP4
names: Caution
names: Function
names: Similarity
messages: Belongs to the globin family. Two-domain flavohemoproteins subfamily.
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

357804:PING RS16830
gene id: 357804:PING_RS16830
uniprot id: A1SZN7
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

357804:PING RS03540
gene id: 357804:PING_RS03540
uniprot id: A1SSR2
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruD family.
messages: Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.

357804:PING RS16495
gene id: 357804:PING_RS16495
uniprot id: A1SZH2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. Carboxylesterase BioH family.
messages: Cytoplasm
messages: Monomer.
messages: The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters.

357804:PING RS07160
gene id: 357804:PING_RS07160
uniprot id: A1SUL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

357804:PING RS12455
gene id: 357804:PING_RS12455
uniprot id: A1SXD0
names: Similarity
messages: Belongs to the GppA/Ppx family.

357804:PING RS10350
gene id: 357804:PING_RS10350
uniprot id: A1SW96
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Catalyzes the last two steps in the biosynthesis of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the DAO family.
messages: In the N-terminal section; belongs to the methyltransferase superfamily. tRNA (mnm(5)s(2)U34)-methyltransferase family.

357804:PING RS01790
gene id: 357804:PING_RS01790
uniprot id: A1SRT4
names: Subcellular Location Annotation
messages: Membrane

357804:PING RS12020
gene id: 357804:PING_RS12020
uniprot id: A1SX57
names: Subcellular Location Annotation
messages: Membrane

357804:PING RS12505
gene id: 357804:PING_RS12505
uniprot id: A1SXE0
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20 family.
messages: Binds 2 Zn(2+) ions per subunit.

357804:PING RS18690
gene id: 357804:PING_RS18690
uniprot id: A1T0P1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

357804:PING RS15550
gene id: 357804:PING_RS15550
uniprot id: A1SZ05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbE subfamily.
messages: Cell inner membrane

357804:PING RS01500
gene id: 357804:PING_RS01500
uniprot id: A1SRM7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial microcompartment
messages: Belongs to the EutB family.
messages: Binds between the large and small subunits.
messages: Catalyzes the deamination of various vicinal amino-alcohols to oxo compounds. Allows this organism to utilize ethanolamine as the sole source of nitrogen and carbon in the presence of vitamin B12.
messages: The basic unit is a heterodimer which dimerizes to form tetramers. The heterotetramers trimerize; 6 large subunits form a core ring with 6 small subunits projecting outwards.

357804:PING RS01025
gene id: 357804:PING_RS01025
uniprot id: A1SRE6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of sn-l,2-diacylglycerol (DAG) to phosphatidic acid. Involved in the recycling of diacylglycerol produced as a by-product during membrane-derived oligosaccharide (MDO) biosynthesis.
messages: Cell inner membrane
messages: Membrane

357804:PING RS17810
gene id: 357804:PING_RS17810
uniprot id: A1T064
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

357804:PING RS04520
gene id: 357804:PING_RS04520
uniprot id: A1ST85
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiK family.
messages: Cytoplasm
messages: Required for efficient ubiquinone (coenzyme Q) biosynthesis. UbiK is probably an accessory factor of Ubi enzymes and facilitates ubiquinone biosynthesis by acting as an assembly factor, a targeting factor, or both.

357804:PING RS03725
gene id: 357804:PING_RS03725
uniprot id: A1SSU7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

357804:PING RS06425
gene id: 357804:PING_RS06425
uniprot id: A1SU80
names: Function
names: Similarity
messages: Belongs to the HypA/HybF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.

357804:PING RS00445
gene id: 357804:PING_RS00445
uniprot id: A1SR34
names: Similarity
messages: Belongs to the Smg family.

357804:PING RS17385
gene id: 357804:PING_RS17385
uniprot id: A1SZZ1
names: Subcellular Location Annotation
messages: Membrane

357804:PING RS12650
gene id: 357804:PING_RS12650
uniprot id: A1SXG9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
messages: Cytoplasm
messages: Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity.

357804:PING RS14900
gene id: 357804:PING_RS14900
uniprot id: A1SYN0
names: Function
names: Similarity
messages: Belongs to the ABC transporter superfamily. Outer membrane lipopolysaccharide export (TC 1.B.42) family.
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane. Probably responsible for energy coupling to the transport system.

357804:PING RS14835
gene id: 357804:PING_RS14835
uniprot id: A1SYL7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AFG1 ATPase family. ZapE subfamily.
messages: Cytoplasm
messages: Interacts with FtsZ.
messages: Reduces the stability of FtsZ polymers in the presence of ATP.

357804:PING RS16220
gene id: 357804:PING_RS16220
uniprot id: A1SZC2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

357804:PING RS06285
gene id: 357804:PING_RS06285
uniprot id: A1SU57
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

357804:PING RS00485
gene id: 357804:PING_RS00485
uniprot id: A1SR42
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

357804:PING RS17525
gene id: 357804:PING_RS17525
uniprot id: A1T015
names: Similarity
messages: Belongs to the asparaginase 1 family.

357804:PING RS09810
gene id: 357804:PING_RS09810
uniprot id: A1SVZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Membrane

357804:PING RS03295
gene id: 357804:PING_RS03295
uniprot id: A1SSL2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division. Important for assembly or stability of the septal ring.

357804:PING RS04840
gene id: 357804:PING_RS04840
uniprot id: A1STE8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

357804:PING RS02745
gene id: 357804:PING_RS02745
uniprot id: A1SSB1
names: Subcellular Location Annotation
messages: Membrane

357804:PING RS19260
gene id: 357804:PING_RS19260
uniprot id: A1T0Z7
names: Function
names: Similarity
messages: Belongs to the ParB family.
messages: Involved in chromosome partition. Localize to both poles of the predivisional cell following completion of DNA replication. Binds to the DNA origin of replication.

357804:PING RS17755
gene id: 357804:PING_RS17755
uniprot id: A1T053
names: Cofactor
names: Function
names: Subunit
messages: Alpha(8)-beta(8). The alpha component is a flavoprotein, the beta component is a hemoprotein.
messages: Binds 1 FAD per subunit.
messages: Binds 1 FMN per subunit.
messages: Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component.

357804:PING RS10000
gene id: 357804:PING_RS10000
uniprot id: A1SW31
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

357804:PING RS17295
gene id: 357804:PING_RS17295
uniprot id: A1SZX3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

357804:PING RS17375
gene id: 357804:PING_RS17375
uniprot id: A1SZY9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

357804:PING RS17470
gene id: 357804:PING_RS17470
uniprot id: A1T004
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

357804:PING RS13605
gene id: 357804:PING_RS13605
uniprot id: A1SXY6
names: Similarity
messages: Belongs to the thioredoxin family.

357804:PING RS19245
gene id: 357804:PING_RS19245
uniprot id: A1T0Z4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase C chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

357804:PING RS15135
gene id: 357804:PING_RS15135
uniprot id: A1SYS4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

357804:PING RS07535
gene id: 357804:PING_RS07535
uniprot id: A1SUT0
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NosZ family.
messages: Binds 2 calcium ions per subunit.
messages: Binds 6 Cu cations per subunit. Each subunit contains 2 copper centers; Cu(A) (binuclear) and Cu(Z) (tetranuclear). Cu(Z) is thought to be the site of nitrous oxide reduction.
messages: Homodimer.
messages: In the C-terminal section; belongs to the cytochrome c oxidase subunit 2 family.
messages: Nitrous-oxide reductase is part of a bacterial respiratory system which is activated under anaerobic conditions in the presence of nitrate or nitrous oxide.
messages: Periplasm
messages: Predicted to be exported by the Tat system. The position of the signal peptide cleavage has not been experimentally proven.

357804:PING RS02095
gene id: 357804:PING_RS02095
uniprot id: A1SRY9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

357804:PING RS08430
gene id: 357804:PING_RS08430
uniprot id: A1SV94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0382 family.
messages: Membrane

357804:PING RS05650
gene id: 357804:PING_RS05650
uniprot id: A1STT9
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A lyase-type mechanism (elimination/hydration) is suggested for the cleavage of the lactyl ether bond of MurNAc 6-phosphate, with the formation of an alpha,beta-unsaturated aldehyde intermediate with (E)-stereochemistry, followed by the syn addition of water to give product.
messages: Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
messages: Homodimer.
messages: Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate. Together with AnmK, is also required for the utilization of anhydro-N-acetylmuramic acid (anhMurNAc) either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.

357804:PING RS17780
gene id: 357804:PING_RS17780
uniprot id: A1T058
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

357804:PING RS18005
gene id: 357804:PING_RS18005
uniprot id: A1T0A2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Cytoplasm
messages: Oligomer of 12 subunits arranged in the form of two hexagons.

357804:PING RS01705
gene id: 357804:PING_RS01705
uniprot id: A1SRR7
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

357804:PING RS01610
gene id: 357804:PING_RS01610
uniprot id: A1SRP9
names: Function
names: Similarity
messages: In the C-terminal section; belongs to the precorrin methyltransferase family.
messages: In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family.
messages: Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme.

357804:PING RS13105
gene id: 357804:PING_RS13105
uniprot id: A1SXQ1
names: Similarity
messages: Belongs to the peptidase M24B family.

357804:PING RS15275
gene id: 357804:PING_RS15275
uniprot id: A1SYV2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

357804:PING RS02965
gene id: 357804:PING_RS02965
uniprot id: A1SSF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

357804:PING RS05970
gene id: 357804:PING_RS05970
uniprot id: A1SU00
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

357804:PING RS18595
gene id: 357804:PING_RS18595
uniprot id: A1T0M1
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

357804:PING RS03175
gene id: 357804:PING_RS03175
uniprot id: A1SSI9
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

357804:PING RS12260
gene id: 357804:PING_RS12260
uniprot id: A1SXA3
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

357804:PING RS15285
gene id: 357804:PING_RS15285
uniprot id: A1SYV4
names: Similarity
messages: Belongs to the skp family.

357804:PING RS17035
gene id: 357804:PING_RS17035
uniprot id: A1SZS3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.

357804:PING RS14360
gene id: 357804:PING_RS14360
uniprot id: A1SYC4
names: Function
messages: E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

357804:PING RS18865
gene id: 357804:PING_RS18865
uniprot id: A1T0S6
names: Function
names: Similarity
messages: Belongs to the CitG/MdcB family.
messages: Involved in the formation of 2-(5''-phosphoribosyl)-3'-dephosphocoenzyme-A, the prosthetic group of the acyl-carrier protein of the malonate decarboxylase.

357804:PING RS11530
gene id: 357804:PING_RS11530
uniprot id: A1SWW4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

357804:PING RS13790
gene id: 357804:PING_RS13790
uniprot id: A1SY17
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

357804:PING RS06535
gene id: 357804:PING_RS06535
uniprot id: A1SUA0
names: Similarity
messages: In the C-terminal section; belongs to the glutathionylspermidine synthase preATP-grasp family.

357804:PING RS18505
gene id: 357804:PING_RS18505
uniprot id: A1T0K3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

357804:PING RS15195
gene id: 357804:PING_RS15195
uniprot id: A1SYT6
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

357804:PING RS11860
gene id: 357804:PING_RS11860
uniprot id: A1SX27
names: Similarity
messages: Belongs to the KAE1 / TsaD family. TsaB subfamily.

357804:PING RS00175
gene id: 357804:PING_RS00175
uniprot id: A1SQY8
names: Similarity
messages: Belongs to the VgrG protein family.

357804:PING RS05330
gene id: 357804:PING_RS05330
uniprot id: A1STM7
names: Similarity
messages: Belongs to the CFA/CMAS family.

357804:PING RS06300
gene id: 357804:PING_RS06300
uniprot id: A1SU60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

357804:PING RS09400
gene id: 357804:PING_RS09400
uniprot id: A1SVR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

357804:PING RS05460
gene id: 357804:PING_RS05460
uniprot id: A1STQ2
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

357804:PING RS10140
gene id: 357804:PING_RS10140
uniprot id: A1SW58
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

357804:PING RS06450
gene id: 357804:PING_RS06450
uniprot id: A1SU85
names: Function
names: Similarity
messages: Belongs to the carbamoyltransferase HypF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases. HypF functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide.

357804:PING RS17005
gene id: 357804:PING_RS17005
uniprot id: A1SZR7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PyrI family.
messages: Binds 1 zinc ion per subunit.
messages: Contains catalytic and regulatory chains.
messages: Involved in allosteric regulation of aspartate carbamoyltransferase.

357804:PING RS18660
gene id: 357804:PING_RS18660
uniprot id: A1T0N5
names: Similarity
messages: Belongs to the FBPase class 2 family.

357804:PING RS14450
gene id: 357804:PING_RS14450
uniprot id: A1SYE2
names: Subcellular Location Annotation
messages: Membrane

357804:PING RS07665
gene id: 357804:PING_RS07665
uniprot id: A1SUV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

357804:PING RS15415
gene id: 357804:PING_RS15415
uniprot id: A1SYX9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease gamma subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

357804:PING RS04875
gene id: 357804:PING_RS04875
uniprot id: A1STF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

357804:PING RS17765
gene id: 357804:PING_RS17765
uniprot id: A1T055
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Catalyzes the formation of sulfite from phosphoadenosine 5'-phosphosulfate (PAPS) using thioredoxin as an electron donor.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

357804:PING RS07660
gene id: 357804:PING_RS07660
uniprot id: A1SUV4
names: Similarity
messages: Belongs to the CvfB family.

357804:PING RS04620
gene id: 357804:PING_RS04620
uniprot id: A1STA5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SeqA family.
messages: Cytoplasm
messages: Homodimer. Polymerizes to form helical filaments.
messages: Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re-initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated.

357804:PING RS00215
gene id: 357804:PING_RS00215
uniprot id: A1SQZ6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

357804:PING RS05400
gene id: 357804:PING_RS05400
uniprot id: A1STP1
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmB subfamily.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.
messages: Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue.

357804:PING RS07595
gene id: 357804:PING_RS07595
uniprot id: A1SUU1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

357804:PING RS13505
gene id: 357804:PING_RS13505
uniprot id: A1SXX0
names: Subcellular Location Annotation
messages: Membrane

357804:PING RS00545
gene id: 357804:PING_RS00545
uniprot id: A1SR54
names: Similarity
messages: Belongs to the HSP15 family.

357804:PING RS14885
gene id: 357804:PING_RS14885
uniprot id: A1SYM7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate.
messages: Homotetramer.

357804:PING RS12565
gene id: 357804:PING_RS12565
uniprot id: A1SXF2
names: Cofactor
messages: Binds 2 Mg(2+) ions per monomer.

357804:PING RS02905
gene id: 357804:PING_RS02905
uniprot id: A1SSE2
names: Similarity
messages: Belongs to the porin LamB (TC 1.B.3) family.

357804:PING RS14105
gene id: 357804:PING_RS14105
uniprot id: A1SY79
names: Similarity
messages: Belongs to the universal stress protein A family.

357804:PING RS09660
gene id: 357804:PING_RS09660
uniprot id: A1SVW5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the zinc-containing alcohol dehydrogenase family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate.
messages: Cytoplasm
messages: Homotetramer.

357804:PING RS15565
gene id: 357804:PING_RS15565
uniprot id: A1SZ08
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmD/CycX/HelD family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

357804:PING RS14045
gene id: 357804:PING_RS14045
uniprot id: A1SY66
names: Similarity
messages: Belongs to the UPF0265 family.

357804:PING RS15675
gene id: 357804:PING_RS15675
uniprot id: A1SZ30
names: Similarity
messages: Belongs to the UPF0235 family.

357804:PING RS02775
gene id: 357804:PING_RS02775
uniprot id: A1SSB7
names: Subcellular Location Annotation
messages: Cell inner membrane

357804:PING RS07045
gene id: 357804:PING_RS07045
uniprot id: A1SUI9
names: Similarity
messages: Belongs to the adrenodoxin/putidaredoxin family.

357804:PING RS18200
gene id: 357804:PING_RS18200
uniprot id: A1T0E1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

357804:PING RS13965
gene id: 357804:PING_RS13965
uniprot id: A1SY50
names: Similarity
messages: Belongs to the UPF0229 family.

357804:PING RS07220
gene id: 357804:PING_RS07220
uniprot id: A1SUM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0316 family.
messages: Cell membrane

357804:PING RS06225
gene id: 357804:PING_RS06225
uniprot id: A1SU49
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

357804:PING RS16915
gene id: 357804:PING_RS16915
uniprot id: A1SZQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Anchors the catalytic components of the fumarate reductase complex to the cell membrane, binds quinones.
messages: Belongs to the FrdD family.
messages: Cell inner membrane
messages: Part of an enzyme complex containing four subunits: a flavoprotein (FrdA), an iron-sulfur protein (FrdB), and two hydrophobic anchor proteins (FrdC and FrdD).

357804:PING RS04040
gene id: 357804:PING_RS04040
uniprot id: A1SSZ8
names: Cofactor
messages: Binds 1 Mg(2+) ion per subunit.

357804:PING RS08450
gene id: 357804:PING_RS08450
uniprot id: A1SV98
names: Subcellular Location Annotation
messages: Membrane

357804:PING RS10895
gene id: 357804:PING_RS10895
uniprot id: A1SWI8
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

357804:PING RS05475
gene id: 357804:PING_RS05475
uniprot id: A1STQ5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the arginase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide.

357804:PING RS14310
gene id: 357804:PING_RS14310
uniprot id: A1SYB4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Syd family.
messages: Cell inner membrane
messages: Interacts with the SecY protein in vivo. May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function.

357804:PING RS04345
gene id: 357804:PING_RS04345
uniprot id: A1ST55
names: Caution
names: Function
names: Similarity
messages: Belongs to the UbiX/PAD1 family.
messages: Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

357804:PING RS19365
gene id: 357804:PING_RS19365
uniprot id: A1STB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpxP/Spy family.
messages: Periplasm

357804:PING RS05990
gene id: 357804:PING_RS05990
uniprot id: A1SU04
names: Similarity
messages: Belongs to the peptidase U62 family.

357804:PING RS09680
gene id: 357804:PING_RS09680
uniprot id: A1SVW9
names: Similarity
messages: Belongs to the DNA polymerase type-B family.

357804:PING RS10535
gene id: 357804:PING_RS10535
uniprot id: A1SWC9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

357804:PING RS01970
gene id: 357804:PING_RS01970
uniprot id: A1SRW7
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

357804:PING RS04700
gene id: 357804:PING_RS04700
uniprot id: A1STC0
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

357804:PING RS04640
gene id: 357804:PING_RS04640
uniprot id: A1STA9
names: Similarity
messages: Belongs to the DEAD box helicase family.

357804:PING RS02805
gene id: 357804:PING_RS02805
uniprot id: A1SSC3
names: Similarity
messages: Belongs to the PhoH family.

357804:PING RS01030
gene id: 357804:PING_RS01030
uniprot id: A1SRE7
names: Similarity
messages: Belongs to the GPAT/DAPAT family.

357804:PING RS00210
gene id: 357804:PING_RS00210
uniprot id: A1SQZ5
names: Subcellular Location Annotation
messages: Membrane

357804:PING RS05090
gene id: 357804:PING_RS05090
uniprot id: A1STI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

357804:PING RS06020
gene id: 357804:PING_RS06020
uniprot id: A1SU10
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

357804:PING RS14435
gene id: 357804:PING_RS14435
uniprot id: A1SYD9
names: Function
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflC subfamily.
messages: HflC and HflK could regulate a protease.

357804:PING RS01915
gene id: 357804:PING_RS01915
uniprot id: A1SRV7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
messages: Homodimer.

357804:PING RS01220
gene id: 357804:PING_RS01220
uniprot id: A1SRI1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

357804:PING RS07410
gene id: 357804:PING_RS07410
uniprot id: A1SUQ6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

357804:PING RS00590
gene id: 357804:PING_RS00590
uniprot id: A1SR63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP K family.
messages: Cell inner membrane
messages: Membrane

357804:PING RS02960
gene id: 357804:PING_RS02960
uniprot id: A1SSF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

357804:PING RS10775
gene id: 357804:PING_RS10775
uniprot id: A1SWG9
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

357804:PING RS04810
gene id: 357804:PING_RS04810
uniprot id: A1STE2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

357804:PING RS13050
gene id: 357804:PING_RS13050
uniprot id: A1SXP1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

357804:PING RS02560
gene id: 357804:PING_RS02560
uniprot id: A1SS81
names: Activity Regulation
names: Function
names: Similarity
names: Subunit
messages: Allosterically activated by N-acetylglucosamine 6-phosphate (GlcNAc6P).
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
messages: Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
messages: Homohexamer.

357804:PING RS06105
gene id: 357804:PING_RS06105
uniprot id: A1SU27
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell inner membrane
messages: Cytoplasm
messages: May bind 1 zinc ion per subunit.
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

357804:PING RS12240
gene id: 357804:PING_RS12240
uniprot id: A1SX98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

357804:PING RS10470
gene id: 357804:PING_RS10470
uniprot id: A1SWB8
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 2 family.
messages: Binds 1 sodium ion per monomer.
messages: Binds 2 magnesium ions per monomer.
messages: Homotetramer.

357804:PING RS16035
gene id: 357804:PING_RS16035
uniprot id: A1SZ98
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

357804:PING RS04565
gene id: 357804:PING_RS04565
uniprot id: A1ST94
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HesB/IscA family.
messages: Binds 1 iron-sulfur cluster per subunit.
messages: Homodimer.
messages: Required for insertion of 4Fe-4S clusters for at least IspG.

357804:PING RS15930
gene id: 357804:PING_RS15930
uniprot id: A1SZ80
names: Subcellular Location Annotation
messages: Cytoplasm

357804:PING RS17390
gene id: 357804:PING_RS17390
uniprot id: A1SZZ2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LuxS family.
messages: Binds 1 Fe cation per subunit.
messages: Homodimer.
messages: Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).

357804:PING RS09785
gene id: 357804:PING_RS09785
uniprot id: A1SVY9
names: Similarity
messages: Belongs to the band 7/mec-2 family.

357804:PING RS01800
gene id: 357804:PING_RS01800
uniprot id: A1SRT6
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily.
messages: Binds 1 NADP(+) per subunit.
messages: Catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose.
messages: Contains a large N-terminal NADP-binding domain, and a smaller C-terminal substrate-binding domain.
messages: Homopentamer.

357804:PING RS03685
gene id: 357804:PING_RS03685
uniprot id: A1SST9
names: Function
names: Similarity
messages: Belongs to the cyanase family.
messages: Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide.

357804:PING RS09700
gene id: 357804:PING_RS09700
uniprot id: A1SVX3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamC family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

357804:PING RS15080
gene id: 357804:PING_RS15080
uniprot id: A1SYR3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 2 lipoyl cofactors covalently.
messages: Forms a 24-polypeptide structural core with octahedral symmetry.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

357804:PING RS02195
gene id: 357804:PING_RS02195
uniprot id: A1SS08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

357804:PING RS07005
gene id: 357804:PING_RS07005
uniprot id: A1SUI1
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

357804:PING RS03015
gene id: 357804:PING_RS03015
uniprot id: A1SSF8
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

357804:PING RS07735
gene id: 357804:PING_RS07735
uniprot id: A1SUX0
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

357804:PING RS09390
gene id: 357804:PING_RS09390
uniprot id: A1SVR3
names: Similarity
messages: Belongs to the UPF0319 family.

357804:PING RS16040
gene id: 357804:PING_RS16040
uniprot id: A1SZ99
names: Similarity
messages: Belongs to the SlyX family.

357804:PING RS01000
gene id: 357804:PING_RS01000
uniprot id: A1SRE1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxL/LpxM/LpxP family.
messages: Catalyzes the transfer of laurate from lauroyl-acyl carrier protein (ACP) to Kdo(2)-lipid IV(A) to form Kdo(2)-(lauroyl)-lipid IV(A).
messages: Cell inner membrane

357804:PING RS00880
gene id: 357804:PING_RS00880
uniprot id: A1SRB7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm

357804:PING RS17815
gene id: 357804:PING_RS17815
uniprot id: A1T065
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

357804:PING RS00600
gene id: 357804:PING_RS00600
uniprot id: A1SR65
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP M family.
messages: Cell inner membrane
messages: Inner membrane component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.
messages: Membrane

357804:PING RS11410
gene id: 357804:PING_RS11410
uniprot id: A1SWT9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YajC family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the SecDF-YidC-YajC translocase complex. The SecDF-YidC-YajC translocase forms a supercomplex with SecYEG, called the holo-translocon (HTL).
messages: The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions.

357804:PING RS14545
gene id: 357804:PING_RS14545
uniprot id: A1SYG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

357804:PING RS00515
gene id: 357804:PING_RS00515
uniprot id: A1SR48
names: Similarity
messages: Belongs to the mannitol dehydrogenase family.

357804:PING RS16255
gene id: 357804:PING_RS16255
uniprot id: A1SZC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbA subfamily.
messages: Periplasm

357804:PING RS10540
gene id: 357804:PING_RS10540
uniprot id: A1SWD0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

357804:PING RS16700
gene id: 357804:PING_RS16700
uniprot id: A1SZL2
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

357804:PING RS02035
gene id: 357804:PING_RS02035
uniprot id: A1SRX7
names: Similarity
messages: Belongs to the UPF0145 family.

357804:PING RS16430
gene id: 357804:PING_RS16430
uniprot id: A1SZG4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DEAD box helicase family. RhlB subfamily.
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA.

357804:PING RS16525
gene id: 357804:PING_RS16525
uniprot id: A1SZH8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

357804:PING RS18340
gene id: 357804:PING_RS18340
uniprot id: A1T0G9
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II FruAB PTS system is involved in fructose transport.

357804:PING RS00065
gene id: 357804:PING_RS00065
uniprot id: A1SQW6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

357804:PING RS12310
gene id: 357804:PING_RS12310
uniprot id: A1SXB1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

357804:PING RS10715
gene id: 357804:PING_RS10715
uniprot id: A1SWF6
names: Function
messages: Repressor involved in choline regulation of the bet genes.
messages: Repressor involved in the biosynthesis of the osmoprotectant glycine betaine. It represses transcription of the choline transporter BetT and the genes of BetAB involved in the synthesis of glycine betaine.

357804:PING RS14065
gene id: 357804:PING_RS14065
uniprot id: A1SY70
names: Subcellular Location Annotation
messages: Membrane

357804:PING RS00935
gene id: 357804:PING_RS00935
uniprot id: A1SRC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0014 family.
messages: Membrane

357804:PING RS17460
gene id: 357804:PING_RS17460
uniprot id: A1T002
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

357804:PING RS15125
gene id: 357804:PING_RS15125
uniprot id: A1SYS2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

357804:PING RS03635
gene id: 357804:PING_RS03635
uniprot id: A1SSS9
names: Subcellular Location Annotation
messages: Membrane

357804:PING RS13915
gene id: 357804:PING_RS13915
uniprot id: A1SY40
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

357804:PING RS06430
gene id: 357804:PING_RS06430
uniprot id: A1SU81
names: Similarity
messages: Belongs to the peptidase A31 family.

357804:PING RS11475
gene id: 357804:PING_RS11475
uniprot id: A1SWV3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThiI family.
messages: Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
messages: Cytoplasm

357804:PING RS02605
gene id: 357804:PING_RS02605
uniprot id: A1SS85
names: Function
names: Subunit
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease.

357804:PING RS14945
gene id: 357804:PING_RS14945
uniprot id: A1SYN9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane
messages: Membrane

357804:PING RS03535
gene id: 357804:PING_RS03535
uniprot id: A1SSR1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

357804:PING RS02830
gene id: 357804:PING_RS02830
uniprot id: A1SSC8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

357804:PING RS13315
gene id: 357804:PING_RS13315
uniprot id: A1SXT6
names: Similarity
messages: Belongs to the EndA/NucM nuclease family.

357804:PING RS13730
gene id: 357804:PING_RS13730
uniprot id: A1SY06
names: Similarity
messages: Belongs to the asparagine synthetase family.

357804:PING RS06010
gene id: 357804:PING_RS06010
uniprot id: A1SU08
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

357804:PING RS06590
gene id: 357804:PING_RS06590
uniprot id: A1SUB1
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

357804:PING RS17595
gene id: 357804:PING_RS17595
uniprot id: A1T027
names: Similarity
messages: Belongs to the alkaline phosphatase family.

357804:PING RS11385
gene id: 357804:PING_RS11385
uniprot id: A1SWT4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase E/G family. RNase E subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per homotetramer.
messages: Cell inner membrane
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation. Within the RNA degradosome, RNase E assembles into a homotetramer formed by a dimer of dimers.
messages: Cytoplasm
messages: Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs.

357804:PING RS15060
gene id: 357804:PING_RS15060
uniprot id: A1SYQ9
names: Subcellular Location Annotation
messages: Membrane

357804:PING RS10230
gene id: 357804:PING_RS10230
uniprot id: A1SW74
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

357804:PING RS10680
gene id: 357804:PING_RS10680
uniprot id: A1SWE9
names: Function
names: Similarity
messages: Belongs to the SELO family.
messages: Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).

357804:PING RS06850
gene id: 357804:PING_RS06850
uniprot id: A1SUG1
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

357804:PING RS08380
gene id: 357804:PING_RS08380
uniprot id: A1SV84
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

357804:PING RS11415
gene id: 357804:PING_RS11415
uniprot id: A1SWU0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

357804:PING RS02625
gene id: 357804:PING_RS02625
uniprot id: A1SS89
names: Similarity
messages: Belongs to the transglycosylase Slt family.

357804:PING RS18295
gene id: 357804:PING_RS18295
uniprot id: A1T0G0
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.

357804:PING RS03970
gene id: 357804:PING_RS03970
uniprot id: A1SSZ1
names: Similarity
messages: Belongs to the UPF0178 family.

357804:PING RS04185
gene id: 357804:PING_RS04185
uniprot id: A1ST25
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PAPS reductase family. CysD subfamily.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

357804:PING RS16610
gene id: 357804:PING_RS16610
uniprot id: A1SZJ5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Nudix hydrolase family. NudC subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Divalent metal cations. Mg(2+) or Mn(2+).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: mRNA decapping enzyme that specifically removes the nicotinamide adenine dinucleotide (NAD) cap from a subset of mRNAs by hydrolyzing the diphosphate linkage to produce nicotinamide mononucleotide (NMN) and 5' monophosphate mRNA. The NAD-cap is present at the 5'-end of some mRNAs and stabilizes RNA against 5'-processing. Has preference for mRNAs with a 5'-end purine. Catalyzes the hydrolysis of a broad range of dinucleotide pyrophosphates.

357804:PING RS14610
gene id: 357804:PING_RS14610
uniprot id: A1SYH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 3 family.
messages: Periplasm

357804:PING RS16130
gene id: 357804:PING_RS16130
uniprot id: A1SZB2
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

357804:PING RS06000
gene id: 357804:PING_RS06000
uniprot id: A1SU06
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. MrdB/RodA subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell wall elongation.

357804:PING RS03960
gene id: 357804:PING_RS03960
uniprot id: A1SSY9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ApbE family.
messages: Cell inner membrane
messages: Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.
messages: Magnesium. Can also use manganese.

357804:PING RS07695
gene id: 357804:PING_RS07695
uniprot id: A1SUW2
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD.
messages: Belongs to the RecD family.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding.

357804:PING RS07980
gene id: 357804:PING_RS07980
uniprot id: A1SV16
names: Subcellular Location Annotation
messages: Membrane

357804:PING RS09995
gene id: 357804:PING_RS09995
uniprot id: A1SW30
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
messages: Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
messages: Homodimer.

357804:PING RS08850
gene id: 357804:PING_RS08850
uniprot id: A1SVG5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

357804:PING RS02110
gene id: 357804:PING_RS02110
uniprot id: A1SRZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptF/LptG family.
messages: Cell inner membrane
messages: Component of the lipopolysaccharide transport and assembly complex. The LptBFG transporter is composed of two ATP-binding proteins (LptB) and two transmembrane proteins (LptF and LptG).
messages: Membrane
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.

357804:PING RS03985
gene id: 357804:PING_RS03985
uniprot id: A1SSZ4
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

357804:PING RS05615
gene id: 357804:PING_RS05615
uniprot id: A1STT2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.

357804:PING RS16390
gene id: 357804:PING_RS16390
uniprot id: A1SZF6
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

357804:PING RS06640
gene id: 357804:PING_RS06640
uniprot id: A1SUC2
names: Function
names: Subcellular Location Annotation
messages: May play a structural or regulatory role in gas vesicle synthesis.
messages: Vesicle
messages: gas vesicle

357804:PING RS10475
gene id: 357804:PING_RS10475
uniprot id: A1SWB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

357804:PING RS11105
gene id: 357804:PING_RS11105
uniprot id: A1SWM9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

357804:PING RS14415
gene id: 357804:PING_RS14415
uniprot id: A1SYD5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

357804:PING RS10300
gene id: 357804:PING_RS10300
uniprot id: A1SW88
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

357804:PING RS03855
gene id: 357804:PING_RS03855
uniprot id: A1SSW9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

357804:PING RS18390
gene id: 357804:PING_RS18390
uniprot id: A1T0I0
names: Subcellular Location Annotation
messages: Cytoplasm

357804:PING RS11490
gene id: 357804:PING_RS11490
uniprot id: A1SWV6
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

357804:PING RS10820
gene id: 357804:PING_RS10820
uniprot id: A1SWH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

357804:PING RS06175
gene id: 357804:PING_RS06175
uniprot id: A1SU39
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

357804:PING RS00740
gene id: 357804:PING_RS00740
uniprot id: A1SR90
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

357804:PING RS01515
gene id: 357804:PING_RS01515
uniprot id: A1SRN0
names: Subcellular Location Annotation
messages: Cytoplasm

357804:PING RS17190
gene id: 357804:PING_RS17190
uniprot id: A1SZV5
names: Subcellular Location Annotation
messages: Membrane

357804:PING RS14020
gene id: 357804:PING_RS14020
uniprot id: A1SY61
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

357804:PING RS02485
gene id: 357804:PING_RS02485
uniprot id: A1SS66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaD Na(+)/H(+) (TC 2.A.62) antiporter family.
messages: Membrane

357804:PING RS03660
gene id: 357804:PING_RS03660
uniprot id: A1SST4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. CmoB family.
messages: Catalyzes carboxymethyl transfer from carboxy-S-adenosyl-L-methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5-carboxymethoxyuridine (cmo5U) at position 34 in tRNAs.
messages: Homotetramer.

357804:PING RS06835
gene id: 357804:PING_RS06835
uniprot id: A1SUF8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.

357804:PING RS10010
gene id: 357804:PING_RS10010
uniprot id: A1SW33
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

357804:PING RS17940
gene id: 357804:PING_RS17940
uniprot id: A1T089
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

357804:PING RS04045
gene id: 357804:PING_RS04045
uniprot id: A1SSZ9
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 2 family.

357804:PING RS17985
gene id: 357804:PING_RS17985
uniprot id: A1T098
names: Function
names: Similarity
messages: Belongs to the peptidase M16 family.
messages: Endopeptidase that degrades small peptides of less than 7 kDa, such as glucagon and insulin.

357804:PING RS17330
gene id: 357804:PING_RS17330
uniprot id: A1SZY0
names: Function
names: Similarity
messages: Acts on ADP-mannose and ADP-glucose as well as ADP-ribose. Prevents glycogen biosynthesis. The reaction catalyzed by this enzyme is a limiting step of the gluconeogenic process.
messages: Belongs to the Nudix hydrolase family. NudF subfamily.

357804:PING RS01900
gene id: 357804:PING_RS01900
uniprot id: A1SRV3
names: Function
names: Similarity
messages: Belongs to the isochorismate synthase family.
messages: Catalyzes the conversion of chorismate to isochorismate.

357804:PING RS06570
gene id: 357804:PING_RS06570
uniprot id: A1SUA7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
messages: Belongs to the azoreductase type 1 family.
messages: Binds 1 FMN per subunit.
messages: Homodimer.
messages: Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones.

357804:PING RS12175
gene id: 357804:PING_RS12175
uniprot id: A1SX85
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

357804:PING RS18450
gene id: 357804:PING_RS18450
uniprot id: A1T0J2
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

357804:PING RS10725
gene id: 357804:PING_RS10725
uniprot id: A1SWF8
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

357804:PING RS17410
gene id: 357804:PING_RS17410
uniprot id: A1SZZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GcdB/MmdB/OadB family.
messages: Catalyzes the decarboxylation of oxaloacetate coupled to Na(+) translocation.
messages: Cell membrane
messages: Heterotrimer of an alpha, a beta and a gamma subunit.
messages: Membrane

357804:PING RS17800
gene id: 357804:PING_RS17800
uniprot id: A1T062
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsrE/TusD family.
messages: Cytoplasm

357804:PING RS07230
gene id: 357804:PING_RS07230
uniprot id: A1SUM4
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

357804:PING RS15655
gene id: 357804:PING_RS15655
uniprot id: A1SZ26
names: Similarity
messages: Belongs to the GSP E family.

357804:PING RS14750
gene id: 357804:PING_RS14750
uniprot id: A1SYK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
messages: Membrane

357804:PING RS00250
gene id: 357804:PING_RS00250
uniprot id: A1SR01
names: Function
names: Similarity
messages: Belongs to the frataxin family.
messages: Involved in iron-sulfur (Fe-S) cluster assembly. May act as a regulator of Fe-S biogenesis.

357804:PING RS14845
gene id: 357804:PING_RS14845
uniprot id: A1SYL9
names: Similarity
messages: Belongs to the peptidase S1C family.

357804:PING RS10155
gene id: 357804:PING_RS10155
uniprot id: A1SW61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

357804:PING RS16550
gene id: 357804:PING_RS16550
uniprot id: A1SZI3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

357804:PING RS06995
gene id: 357804:PING_RS06995
uniprot id: A1SUH9
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

357804:PING RS03110
gene id: 357804:PING_RS03110
uniprot id: A1SSH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0060 family.
messages: Cell inner membrane

357804:PING RS18010
gene id: 357804:PING_RS18010
uniprot id: A1T0A3
names: Similarity
messages: Belongs to the glutamine synthetase family.

357804:PING RS13920
gene id: 357804:PING_RS13920
uniprot id: A1SY41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

357804:PING RS13045
gene id: 357804:PING_RS13045
uniprot id: A1SXP0
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
messages: O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.

357804:PING RS06980
gene id: 357804:PING_RS06980
uniprot id: A1SUH6
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

357804:PING RS12190
gene id: 357804:PING_RS12190
uniprot id: A1SX88
names: Similarity
messages: Belongs to the glucose-6-phosphate 1-epimerase family.

357804:PING RS01225
gene id: 357804:PING_RS01225
uniprot id: A1SRI2
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily.

357804:PING RS09030
gene id: 357804:PING_RS09030
uniprot id: A1SVJ5
names: Similarity
messages: Belongs to the class-II DAHP synthase family.

357804:PING RS01235
gene id: 357804:PING_RS01235
uniprot id: A1SRI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm
messages: In the N-terminal section; belongs to the lyase 1 family. Argininosuccinate lyase subfamily.

357804:PING RS11850
gene id: 357804:PING_RS11850
uniprot id: A1SX25
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

357804:PING RS04075
gene id: 357804:PING_RS04075
uniprot id: A1ST04
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

357804:PING RS07055
gene id: 357804:PING_RS07055
uniprot id: A1SUJ1
names: Similarity
messages: Belongs to the peptidase M17 family.

357804:PING RS03030
gene id: 357804:PING_RS03030
uniprot id: A1SSG1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

357804:PING RS03745
gene id: 357804:PING_RS03745
uniprot id: A1SSV2
names: Similarity
messages: Belongs to the UPF0325 family.

357804:PING RS17485
gene id: 357804:PING_RS17485
uniprot id: A1T007
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 independent methionine synthase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.

357804:PING RS15300
gene id: 357804:PING_RS15300
uniprot id: A1SYV7
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).

357804:PING RS06840
gene id: 357804:PING_RS06840
uniprot id: A1SUF9
names: Similarity
messages: Belongs to the BMP lipoprotein family.

357804:PING RS06150
gene id: 357804:PING_RS06150
uniprot id: A1SU34
names: Similarity
messages: Belongs to the SUI1 family.

357804:PING RS10830
gene id: 357804:PING_RS10830
uniprot id: A1SWH9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. sn-glycerol-3-phosphate importer (TC 3.A.1.1.3) family.
messages: Cell inner membrane
messages: Part of the ABC transporter complex UgpBAEC involved in sn-glycerol-3-phosphate (G3P) import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (UgpC), two transmembrane proteins (UgpA and UgpE) and a solute-binding protein (UgpB).

357804:PING RS05105
gene id: 357804:PING_RS05105
uniprot id: A1STI3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Monomer.

357804:PING RS11740
gene id: 357804:PING_RS11740
uniprot id: A1SX03
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

357804:PING RS11715
gene id: 357804:PING_RS11715
uniprot id: A1SWZ8
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

357804:PING RS13410
gene id: 357804:PING_RS13410
uniprot id: A1SXV1
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

357804:PING RS17445
gene id: 357804:PING_RS17445
uniprot id: A1SZZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s).
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

357804:PING RS01605
gene id: 357804:PING_RS01605
uniprot id: A1SRP8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LDH/MDH superfamily. MDH type 1 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.
messages: Homodimer.

357804:PING RS15560
gene id: 357804:PING_RS15560
uniprot id: A1SZ07
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmE/CycJ family.
messages: Cell inner membrane
messages: Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.

357804:PING RS11060
gene id: 357804:PING_RS11060
uniprot id: A1SWM1
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the peroxidase family. Peroxidase/catalase subfamily.
messages: Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.
messages: Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.
messages: Homodimer or homotetramer.

357804:PING RS05595
gene id: 357804:PING_RS05595
uniprot id: A1STS8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YciB family.
messages: Cell inner membrane
messages: Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.

357804:PING RS05190
gene id: 357804:PING_RS05190
uniprot id: A1STJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 32 family.
messages: Cytoplasm
messages: Enables the bacterium to metabolize sucrose as a sole carbon source.

357804:PING RS17825
gene id: 357804:PING_RS17825
uniprot id: A1T067
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

357804:PING RS11345
gene id: 357804:PING_RS11345
uniprot id: A1SWS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

357804:PING RS11395
gene id: 357804:PING_RS11395
uniprot id: A1SWT6
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cell membrane
messages: Homodimer.
messages: May be involved in cell division.

357804:PING RS18605
gene id: 357804:PING_RS18605
uniprot id: A1T0M3
names: Similarity
messages: Belongs to the AlaDH/PNT family.

357804:PING RS17030
gene id: 357804:PING_RS17030
uniprot id: A1SZS2
names: Subcellular Location Annotation
messages: Membrane

357804:PING RS04835
gene id: 357804:PING_RS04835
uniprot id: A1STE7
names: Function
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.
messages: Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively. Also cleaves 5'-deoxyadenosine, a toxic by-product of radical S-adenosylmethionine (SAM) enzymes, into 5-deoxyribose and adenine.

357804:PING RS04070
gene id: 357804:PING_RS04070
uniprot id: A1ST03
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. Fucose synthase subfamily.
messages: Catalyzes the two-step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.

357804:PING RS05825
gene id: 357804:PING_RS05825
uniprot id: A1STX3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

357804:PING RS18695
gene id: 357804:PING_RS18695
uniprot id: A1T0P2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

357804:PING RS09910
gene id: 357804:PING_RS09910
uniprot id: A1SW15
names: Similarity
messages: Belongs to the UPF0502 family.

357804:PING RS00550
gene id: 357804:PING_RS00550
uniprot id: A1SR55
names: Similarity
messages: Belongs to the GSP C family.

357804:PING RS19400
gene id: 357804:PING_RS19400
uniprot id: A1SU75
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

357804:PING RS04015
gene id: 357804:PING_RS04015
uniprot id: A2BNC6
names: Similarity
messages: Belongs to the HepT RNase toxin family.

357804:PING RS06795
gene id: 357804:PING_RS06795
uniprot id: A1SUF0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

357804:PING RS17170
gene id: 357804:PING_RS17170
uniprot id: A1SZV1
names: Subcellular Location Annotation
messages: Membrane

357804:PING RS03905
gene id: 357804:PING_RS03905
uniprot id: A1SSX8
names: Function
names: Similarity
messages: Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.

357804:PING RS15670
gene id: 357804:PING_RS15670
uniprot id: A1SZ29
names: Similarity
messages: Belongs to the YggT family.

357804:PING RS11505
gene id: 357804:PING_RS11505
uniprot id: A1SWV9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RdgC family.
messages: May be involved in recombination.
messages: nucleoid

357804:PING RS12225
gene id: 357804:PING_RS12225
uniprot id: A1SX95
names: Function
names: Similarity
messages: Belongs to the Thz kinase family.
messages: Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).

357804:PING RS00235
gene id: 357804:PING_RS00235
uniprot id: A1SQZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.

357804:PING RS18475
gene id: 357804:PING_RS18475
uniprot id: A1T0J7
names: Similarity
messages: Belongs to the MotB family.

357804:PING RS01845
gene id: 357804:PING_RS01845
uniprot id: A1SRU5
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

357804:PING RS06810
gene id: 357804:PING_RS06810
uniprot id: A1SUF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThrE exporter (TC 2.A.79) family.
messages: Membrane

357804:PING RS17240
gene id: 357804:PING_RS17240
uniprot id: A1SZW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

357804:PING RS02955
gene id: 357804:PING_RS02955
uniprot id: A1SSF1
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

357804:PING RS08470
gene id: 357804:PING_RS08470
uniprot id: A1SVA2
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

357804:PING RS15395
gene id: 357804:PING_RS15395
uniprot id: A1SYX5
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

357804:PING RS04775
gene id: 357804:PING_RS04775
uniprot id: A1STD5
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

357804:PING RS06065
gene id: 357804:PING_RS06065
uniprot id: A1SU19
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell inner membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).

357804:PING RS08015
gene id: 357804:PING_RS08015
uniprot id: A1SV24
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.

357804:PING RS08620
gene id: 357804:PING_RS08620
uniprot id: A1SVC1
names: Similarity
messages: Belongs to the band 7/mec-2 family.

357804:PING RS07730
gene id: 357804:PING_RS07730
uniprot id: A1SUW9
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

357804:PING RS07760
gene id: 357804:PING_RS07760
uniprot id: A1SUX5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

357804:PING RS01720
gene id: 357804:PING_RS01720
uniprot id: A1SRS0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatB family.
messages: Cell inner membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

357804:PING RS18435
gene id: 357804:PING_RS18435
uniprot id: A1T0I9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgI family.
messages: Periplasm
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

357804:PING RS07175
gene id: 357804:PING_RS07175
uniprot id: A1SUL5
names: Subcellular Location Annotation
messages: Membrane

357804:PING RS03225
gene id: 357804:PING_RS03225
uniprot id: A1SSJ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TER reductase family.
messages: Involved in the final reduction of the elongation cycle of fatty acid synthesis (FAS II). Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP).
messages: Monomer.

357804:PING RS13680
gene id: 357804:PING_RS13680
uniprot id: A1SXZ7
names: Similarity
messages: Belongs to the RutC family.

357804:PING RS05465
gene id: 357804:PING_RS05465
uniprot id: A1STQ3
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAL/histidase family.
messages: Contains an active site 4-methylidene-imidazol-5-one (MIO), which is formed autocatalytically by cyclization and dehydration of residues Ala-Ser-Gly.
messages: Cytoplasm

357804:PING RS04155
gene id: 357804:PING_RS04155
uniprot id: A1ST18
names: Similarity
messages: Belongs to the polysaccharide synthase family.

357804:PING RS04165
gene id: 357804:PING_RS04165
uniprot id: A1ST20
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

357804:PING RS13545
gene id: 357804:PING_RS13545
uniprot id: A1SXX7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A highly abundant outer membrane lipoprotein that controls the distance between the inner and outer membranes. The only protein known to be covalently linked to the peptidoglycan network (PGN). Also non-covalently binds the PGN. The link between the cell outer membrane and PGN contributes to maintenance of the structural and functional integrity of the cell envelope, and maintains the correct distance between the PGN and the outer membrane.
messages: Belongs to the Lpp family.
messages: Cell outer membrane
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: cell wall

357804:PING RS18170
gene id: 357804:PING_RS18170
uniprot id: A1T0D5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

357804:PING RS07775
gene id: 357804:PING_RS07775
uniprot id: A1SUX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LysR transcriptional regulatory family.
messages: Cytoplasm

357804:PING RS11265
gene id: 357804:PING_RS11265
uniprot id: A1SWR0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

357804:PING RS17250
gene id: 357804:PING_RS17250
uniprot id: A1SZW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

357804:PING RS00535
gene id: 357804:PING_RS00535
uniprot id: A1SR52
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Cytoplasm
messages: Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
messages: Monomer.

357804:PING RS02505
gene id: 357804:PING_RS02505
uniprot id: A1SS70
names: Similarity
messages: Belongs to the N-Me-Phe pilin family.

357804:PING RS03315
gene id: 357804:PING_RS03315
uniprot id: A1SSL6
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. TrmA subfamily.
messages: Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA).

357804:PING RS03945
gene id: 357804:PING_RS03945
uniprot id: A1SSY6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

357804:PING RS05130
gene id: 357804:PING_RS05130
uniprot id: A1STI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HflD family.
messages: Cell inner membrane
messages: Cytoplasm

357804:PING RS14035
gene id: 357804:PING_RS14035
uniprot id: A1SY64
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.

357804:PING RS11595
gene id: 357804:PING_RS11595
uniprot id: A1SWX5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

357804:PING RS17670
gene id: 357804:PING_RS17670
uniprot id: A1T038
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

357804:PING RS08215
gene id: 357804:PING_RS08215
uniprot id: A1SV56
names: Similarity
messages: Belongs to the PrpD family.

357804:PING RS05570
gene id: 357804:PING_RS05570
uniprot id: A1STS3
names: Domain
names: Function
names: Subcellular Location Annotation
messages: Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation.
messages: Periplasm
messages: The PPIase activity resides only in the second parvulin domain. The N-terminal region and the C-terminal tail are necessary and sufficient for the chaperone activity of SurA. The PPIase activity is dispensable for SurA to function as a chaperone. The N-terminal region and the C-terminal tail are also required for porin recognition.

357804:PING RS09705
gene id: 357804:PING_RS09705
uniprot id: A1SVX4
names: Similarity
messages: Belongs to the SAICAR synthetase family.

357804:PING RS08095
gene id: 357804:PING_RS08095
uniprot id: A1SV39
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the DNA photolyase class-1 family.
messages: Binds 1 5,10-methenyltetrahydrofolate (MTHF) per subunit.
messages: Binds 1 FAD per subunit.
messages: May have a photoreceptor function.

357804:PING RS15260
gene id: 357804:PING_RS15260
uniprot id: A1SYU9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

357804:PING RS18810
gene id: 357804:PING_RS18810
uniprot id: A1T0R6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

357804:PING RS03530
gene id: 357804:PING_RS03530
uniprot id: A1SSR0
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

357804:PING RS09260
gene id: 357804:PING_RS09260
uniprot id: A1SVN9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. Epd subfamily.
messages: Catalyzes the NAD-dependent conversion of D-erythrose 4-phosphate to 4-phosphoerythronate.
messages: Cytoplasm
messages: Homotetramer.

357804:PING RS11485
gene id: 357804:PING_RS11485
uniprot id: A1SWV5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Homodimer.

357804:PING RS15660
gene id: 357804:PING_RS15660
uniprot id: A1SZ27
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

357804:PING RS06320
gene id: 357804:PING_RS06320
uniprot id: A1SU62
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

357804:PING RS05995
gene id: 357804:PING_RS05995
uniprot id: A1SU05
names: Function
names: Similarity
messages: Belongs to the RlpA family.
messages: Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.

357804:PING RS01595
gene id: 357804:PING_RS01595
uniprot id: A1SRP6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

357804:PING RS05455
gene id: 357804:PING_RS05455
uniprot id: A1STQ1
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

357804:PING RS11390
gene id: 357804:PING_RS11390
uniprot id: A1SWT5
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

357804:PING RS12575
gene id: 357804:PING_RS12575
uniprot id: A1SXF4
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

357804:PING RS15225
gene id: 357804:PING_RS15225
uniprot id: A1SYU2
names: Function
names: Similarity
messages: Belongs to the FrsA family.
messages: Catalyzes the hydrolysis of esters.

357804:PING RS14420
gene id: 357804:PING_RS14420
uniprot id: A1SYD6
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

357804:PING RS04180
gene id: 357804:PING_RS04180
uniprot id: A1ST24
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. WecA subfamily.
messages: Catalyzes the transfer of the GlcNAc-1-phosphate moiety from UDP-GlcNAc onto the carrier lipid undecaprenyl phosphate (C55-P), yielding GlcNAc-pyrophosphoryl-undecaprenyl (GlcNAc-PP-C55).
messages: Cell inner membrane
messages: Membrane

357804:PING RS11350
gene id: 357804:PING_RS11350
uniprot id: A1SWS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

357804:PING RS08505
gene id: 357804:PING_RS08505
uniprot id: A1SVA7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Monomer.

357804:PING RS18420
gene id: 357804:PING_RS18420
uniprot id: A1T0I6
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Secreted

357804:PING RS04305
gene id: 357804:PING_RS04305
uniprot id: A1ST47
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

357804:PING RS16825
gene id: 357804:PING_RS16825
uniprot id: A1SZN6
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

357804:PING RS11340
gene id: 357804:PING_RS11340
uniprot id: A1SWS5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

357804:PING RS10310
gene id: 357804:PING_RS10310
uniprot id: A1SW90
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 3 family. NagZ subfamily.
messages: Cytoplasm
messages: Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides.

357804:PING RS00320
gene id: 357804:PING_RS00320
uniprot id: A1SR14
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

357804:PING RS18775
gene id: 357804:PING_RS18775
uniprot id: A1T0Q9
names: Function
names: Similarity
messages: Belongs to the uroporphyrinogen-III synthase family.
messages: Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.

357804:PING RS05125
gene id: 357804:PING_RS05125
uniprot id: A1STI7
names: Function
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
messages: Catalyzes two reactions in de novo purine nucleotide biosynthesis. Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate.

357804:PING RS16905
gene id: 357804:PING_RS16905
uniprot id: A1SZQ1
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

357804:PING RS09330
gene id: 357804:PING_RS09330
uniprot id: A1SVQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

357804:PING RS06050
gene id: 357804:PING_RS06050
uniprot id: A1SU16
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell inner membrane

357804:PING RS05690
gene id: 357804:PING_RS05690
uniprot id: A1STU7
names: Similarity
messages: Belongs to the ArsC family.

357804:PING RS00075
gene id: 357804:PING_RS00075
uniprot id: A1SQW8
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

357804:PING RS12690
gene id: 357804:PING_RS12690
uniprot id: A1SXH7
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the type IA topoisomerase family.
messages: Binds two Mg(2+) per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

357804:PING RS18175
gene id: 357804:PING_RS18175
uniprot id: A1T0D6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

357804:PING RS13080
gene id: 357804:PING_RS13080
uniprot id: A1SXP7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

357804:PING RS01540
gene id: 357804:PING_RS01540
uniprot id: A1SRN5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the selenophosphate synthase 1 family. Class I subfamily.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Homodimer.
messages: Synthesizes selenophosphate from selenide and ATP.

357804:PING RS13585
gene id: 357804:PING_RS13585
uniprot id: A1SXY3
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

357804:PING RS16570
gene id: 357804:PING_RS16570
uniprot id: A1SZI7
names: Function
names: Similarity
messages: Belongs to the Dus family. DusB subfamily.
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

357804:PING RS11215
gene id: 357804:PING_RS11215
uniprot id: A1SWP9
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NapB family.
messages: Binds 2 heme C groups per subunit.
messages: Component of the periplasmic nitrate reductase NapAB complex composed of NapA and NapB.
messages: Electron transfer subunit of the periplasmic nitrate reductase complex NapAB.
messages: Periplasm

357804:PING RS00890
gene id: 357804:PING_RS00890
uniprot id: A1SRB9
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

357804:PING RS05720
gene id: 357804:PING_RS05720
uniprot id: A1STV3
names: Function
names: Similarity
messages: Belongs to the MinE family.
messages: Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.

357804:PING RS21515
gene id: 357804:PING_RS21515
uniprot id: A1SZM0
names: Similarity
messages: Belongs to the ice-binding protein family.

357804:PING RS08425
gene id: 357804:PING_RS08425
uniprot id: A1SV93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

357804:PING RS17055
gene id: 357804:PING_RS17055
uniprot id: A1SZS7
names: Function
names: Similarity
messages: Belongs to the flavodoxin family.
messages: Low-potential electron donor to a number of redox enzymes.

357804:PING RS14350
gene id: 357804:PING_RS14350
uniprot id: A1SYC2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: Forms a 24-polypeptide structural core with octahedral symmetry.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

357804:PING RS04340
gene id: 357804:PING_RS04340
uniprot id: A1ST54
names: Function
names: Similarity
messages: Belongs to the MurCDEF family. Mpl subfamily.
messages: Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl-meso-diaminopimelate by linking it to UDP-N-acetylmuramate.

357804:PING RS04815
gene id: 357804:PING_RS04815
uniprot id: A1STE3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

357804:PING RS12580
gene id: 357804:PING_RS12580
uniprot id: A1SXF5
names: Subcellular Location Annotation
messages: Cytoplasm

357804:PING RS05375
gene id: 357804:PING_RS05375
uniprot id: A1STN6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

357804:PING RS12930
gene id: 357804:PING_RS12930
uniprot id: A1SXL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

357804:PING RS14085
gene id: 357804:PING_RS14085
uniprot id: A1SY74
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

357804:PING RS05115
gene id: 357804:PING_RS05115
uniprot id: A1STI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

357804:PING RS16270
gene id: 357804:PING_RS16270
uniprot id: A1SZD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

357804:PING RS17720
gene id: 357804:PING_RS17720
uniprot id: A1T047
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

357804:PING RS10600
gene id: 357804:PING_RS10600
uniprot id: A1SWD7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

357804:PING RS06005
gene id: 357804:PING_RS06005
uniprot id: A1SU07
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transpeptidase family. MrdA subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall.
messages: Cell inner membrane

357804:PING RS01130
gene id: 357804:PING_RS01130
uniprot id: A1SRG6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

357804:PING RS04200
gene id: 357804:PING_RS04200
uniprot id: A1ST28
names: Subcellular Location Annotation
messages: Membrane

357804:PING RS15205
gene id: 357804:PING_RS15205
uniprot id: A1SYT8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

357804:PING RS09150
gene id: 357804:PING_RS09150
uniprot id: A1SVL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CbbQ/NirQ/NorQ/GpvN family.
messages: Vesicle
messages: gas vesicle

357804:PING RS07915
gene id: 357804:PING_RS07915
uniprot id: A1SV04
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

357804:PING RS04445
gene id: 357804:PING_RS04445
uniprot id: A1ST71
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

357804:PING RS02610
gene id: 357804:PING_RS02610
uniprot id: A1SS86
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

357804:PING RS12370
gene id: 357804:PING_RS12370
uniprot id: A1SXB5
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaved by autocatalysis into a large and a small subunit.
messages: This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide.

357804:PING RS19240
gene id: 357804:PING_RS19240
uniprot id: A1T0Z3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell inner membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.

357804:PING RS03975
gene id: 357804:PING_RS03975
uniprot id: A1SSZ2
names: Subcellular Location Annotation
messages: Cytoplasm

357804:PING RS07330
gene id: 357804:PING_RS07330
uniprot id: A1SUP2
names: Similarity
messages: Belongs to the CopC family.

357804:PING RS06855
gene id: 357804:PING_RS06855
uniprot id: A1SUG2
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

357804:PING RS13020
gene id: 357804:PING_RS13020
uniprot id: A1SXN5
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

357804:PING RS18560
gene id: 357804:PING_RS18560
uniprot id: A1T0L4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type III secretion exporter family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

357804:PING RS01015
gene id: 357804:PING_RS01015
uniprot id: A1SRE4
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

357804:PING RS07690
gene id: 357804:PING_RS07690
uniprot id: A1SUW1
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA.
messages: Belongs to the helicase family. UvrD subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding. Interacts with RecA.
messages: The C-terminal domain has nuclease activity and interacts with RecD. It interacts with RecA, facilitating its loading onto ssDNA.
messages: The N-terminal DNA-binding domain is a ssDNA-dependent ATPase and has ATP-dependent 3'-5' helicase function. This domain interacts with RecC.

357804:PING RS14915
gene id: 357804:PING_RS14915
uniprot id: A1SYN3
names: Function
names: Similarity
messages: Belongs to the RapZ-like family.
messages: Displays ATPase and GTPase activities.

357804:PING RS09760
gene id: 357804:PING_RS09760
uniprot id: A1SVY4
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

357804:PING RS19055
gene id: 357804:PING_RS19055
uniprot id: A1T0V7
names: Similarity
messages: Belongs to the phosphate/phosphite/phosphonate binding protein family.

357804:PING RS12195
gene id: 357804:PING_RS12195
uniprot id: A1SX89
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

357804:PING RS14765
gene id: 357804:PING_RS14765
uniprot id: A1SYK4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/UDP phosphorylase family.
messages: Catalyzes the reversible phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
messages: Homohexamer; trimer of homodimers.

357804:PING RS06770
gene id: 357804:PING_RS06770
uniprot id: A1SUE5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

357804:PING RS05510
gene id: 357804:PING_RS05510
uniprot id: A1STR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Periplasm

357804:PING RS05910
gene id: 357804:PING_RS05910
uniprot id: A1STY8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

357804:PING RS13825
gene id: 357804:PING_RS13825
uniprot id: A1SY23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaD Na(+)/H(+) (TC 2.A.62) antiporter family.
messages: Membrane

357804:PING RS18780
gene id: 357804:PING_RS18780
uniprot id: A1T0R0
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

357804:PING RS17900
gene id: 357804:PING_RS17900
uniprot id: A1T081
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

357804:PING RS13695
gene id: 357804:PING_RS13695
uniprot id: A1SY00
names: Subcellular Location Annotation
messages: Membrane

357804:PING RS07995
gene id: 357804:PING_RS07995
uniprot id: A1SV19
names: Subcellular Location Annotation
messages: Membrane

357804:PING RS08790
gene id: 357804:PING_RS08790
uniprot id: A1SVF4
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

357804:PING RS18955
gene id: 357804:PING_RS18955
uniprot id: A1T0U0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

357804:PING RS01740
gene id: 357804:PING_RS01740
uniprot id: A1SRS4
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).

357804:PING RS11540
gene id: 357804:PING_RS11540
uniprot id: A1SWW6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

357804:PING RS04255
gene id: 357804:PING_RS04255
uniprot id: A1ST38
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
messages: Cytoplasm
messages: Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.

357804:PING RS14780
gene id: 357804:PING_RS14780
uniprot id: A1SYK7
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

357804:PING RS06575
gene id: 357804:PING_RS06575
uniprot id: A1SUA8
names: Similarity
messages: Belongs to the UPF0303 family.

357804:PING RS07875
gene id: 357804:PING_RS07875
uniprot id: A1SUZ7
names: Cofactor
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

357804:PING RS19005
gene id: 357804:PING_RS19005
uniprot id: A1T0U7
names: Function
names: Similarity
messages: Belongs to the ribose 1,5-bisphosphokinase family.
messages: Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP).

357804:PING RS05645
gene id: 357804:PING_RS05645
uniprot id: A1STT8
names: Similarity
messages: Belongs to the UDPGP type 2 family.

357804:PING RS07615
gene id: 357804:PING_RS07615
uniprot id: A1SUU5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
messages: Forms an icosahedral capsid composed of 60 subunits, arranged as a dodecamer of pentamers.

357804:PING RS03700
gene id: 357804:PING_RS03700
uniprot id: A1SSU2
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

357804:PING RS07040
gene id: 357804:PING_RS07040
uniprot id: A1SUI8
names: Function
names: Similarity
messages: Belongs to the heat shock protein 70 family.
messages: Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB.

357804:PING RS05780
gene id: 357804:PING_RS05780
uniprot id: A1STW5
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

357804:PING RS16475
gene id: 357804:PING_RS16475
uniprot id: A1SZG8
names: Function
names: Similarity
messages: Belongs to the nucleoside phosphorylase PpnP family.
messages: Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions.

357804:PING RS00905
gene id: 357804:PING_RS00905
uniprot id: A1SRC2
names: Similarity
messages: Belongs to the glyoxalase I family.

357804:PING RS03125
gene id: 357804:PING_RS03125
uniprot id: A1SSH9
names: Similarity
messages: Belongs to the Gfa family.

357804:PING RS09060
gene id: 357804:PING_RS09060
uniprot id: A1SVK1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

357804:PING RS17760
gene id: 357804:PING_RS17760
uniprot id: A1T054
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Alpha(8)-beta(8). The alpha component is a flavoprotein, the beta component is a hemoprotein.
messages: Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Binds 1 siroheme per subunit.
messages: Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate.

357804:PING RS05600
gene id: 357804:PING_RS05600
uniprot id: A1STS9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

357804:PING RS18565
gene id: 357804:PING_RS18565
uniprot id: A1T0L5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Membrane

357804:PING RS18750
gene id: 357804:PING_RS18750
uniprot id: A1T0Q4
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

357804:PING RS18065
gene id: 357804:PING_RS18065
uniprot id: A1T0B4
names: Caution
names: Function
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the 2'-O methylation of guanosine at position 18 in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

357804:PING RS15575
gene id: 357804:PING_RS15575
uniprot id: A1SZ10
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmB/CycW/HelB family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

357804:PING RS14800
gene id: 357804:PING_RS14800
uniprot id: A1SYL1
names: Similarity
messages: Belongs to the GST superfamily. HSP26 family.

357804:PING RS04505
gene id: 357804:PING_RS04505
uniprot id: A1ST82
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

357804:PING RS04635
gene id: 357804:PING_RS04635
uniprot id: A1STA8
names: Similarity
messages: Belongs to the UPF0381 family.

357804:PING RS03755
gene id: 357804:PING_RS03755
uniprot id: A1SSV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EamA transporter family.
messages: Membrane

357804:PING RS19555
gene id: 357804:PING_RS19555
uniprot id: A1SX62
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ZipA family.
messages: Cell inner membrane
messages: Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins.
messages: Interacts with FtsZ via their C-terminal domains.

357804:PING RS06125
gene id: 357804:PING_RS06125
uniprot id: A1SU31
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

357804:PING RS10990
gene id: 357804:PING_RS10990
uniprot id: A1SWK6
names: Subcellular Location Annotation
messages: Membrane

357804:PING RS14215
gene id: 357804:PING_RS14215
uniprot id: A1SY98
names: Similarity
messages: Belongs to the LEA type 2 family.

357804:PING RS01505
gene id: 357804:PING_RS01505
uniprot id: A1SRM8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial microcompartment
messages: Belongs to the EutC family.
messages: Binds between the large and small subunits.
messages: Catalyzes the deamination of various vicinal amino-alcohols to oxo compounds. Allows this organism to utilize ethanolamine as the sole source of nitrogen and carbon in the presence of external vitamin B12.
messages: The basic unit is a heterodimer which dimerizes to form tetramers. The heterotetramers trimerize; 6 large subunits form a core ring with 6 small subunits projecting outwards.

357804:PING RS05580
gene id: 357804:PING_RS05580
uniprot id: A1STS5
names: Domain
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cell inner membrane
messages: Homodimer.
messages: Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB/RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host.
messages: The transmembrane domain is a dimerization domain.

357804:PING RS12485
gene id: 357804:PING_RS12485
uniprot id: A1SXD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

357804:PING RS07210
gene id: 357804:PING_RS07210
uniprot id: A1SUM1
names: Subcellular Location Annotation
messages: Membrane

357804:PING RS16735
gene id: 357804:PING_RS16735
uniprot id: A1SZL9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

357804:PING RS11610
gene id: 357804:PING_RS11610
uniprot id: A1SWX8
names: Function
names: Similarity
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.
messages: E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

357804:PING RS16615
gene id: 357804:PING_RS16615
uniprot id: A1SZJ6
names: Similarity
messages: Belongs to the Rsd/AlgQ family.

357804:PING RS03805
gene id: 357804:PING_RS03805
uniprot id: A1SSW4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TolB family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: Periplasm
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

357804:PING RS18455
gene id: 357804:PING_RS18455
uniprot id: A1T0J3
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

357804:PING RS04320
gene id: 357804:PING_RS04320
uniprot id: A1ST50
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

357804:PING RS12860
gene id: 357804:PING_RS12860
uniprot id: A1SXK5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

357804:PING RS16520
gene id: 357804:PING_RS16520
uniprot id: A1SZH7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
messages: Homodimer.

357804:PING RS00340
gene id: 357804:PING_RS00340
uniprot id: A1SR18
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nucleoid occlusion factor SlmA family.
messages: Homodimer. Interacts with FtsZ.
messages: Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions.
messages: nucleoid

357804:PING RS04740
gene id: 357804:PING_RS04740
uniprot id: A1STC8
names: Function
names: Similarity
messages: Belongs to the LpxK family.
messages: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

357804:PING RS01725
gene id: 357804:PING_RS01725
uniprot id: A1SRS1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell inner membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

357804:PING RS09610
gene id: 357804:PING_RS09610
uniprot id: A1SVV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Cell membrane
messages: Membrane

357804:PING RS16650
gene id: 357804:PING_RS16650
uniprot id: A1SZK3
names: Function
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is unknown.

357804:PING RS03050
gene id: 357804:PING_RS03050
uniprot id: A1SSG4
names: Function
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.

357804:PING RS07860
gene id: 357804:PING_RS07860
uniprot id: A1SUZ4
names: Subcellular Location Annotation
messages: Membrane

357804:PING RS17530
gene id: 357804:PING_RS17530
uniprot id: A1T016
names: Cofactor
messages: Binds 2 iron ions per subunit.

357804:PING RS04750
gene id: 357804:PING_RS04750
uniprot id: A1STD0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

357804:PING RS14855
gene id: 357804:PING_RS14855
uniprot id: A1SYM1
names: Similarity
messages: Belongs to the BolA/IbaG family.

357804:PING RS09655
gene id: 357804:PING_RS09655
uniprot id: A1SVW4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.
messages: Homodimer.

357804:PING RS08400
gene id: 357804:PING_RS08400
uniprot id: A1SV88
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

357804:PING RS02470
gene id: 357804:PING_RS02470
uniprot id: A1SS63
names: Function
names: Similarity
messages: Belongs to the ATPase gamma chain family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

357804:PING RS03055
gene id: 357804:PING_RS03055
uniprot id: A1SSG5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MsrP family.
messages: Binds 1 Mo-molybdopterin (Mo-MPT) cofactor per subunit.
messages: Heterodimer of a catalytic subunit (MsrP) and a heme-binding subunit (MsrQ).
messages: Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide.
messages: Periplasm

357804:PING RS14390
gene id: 357804:PING_RS14390
uniprot id: A1SYD0
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

357804:PING RS16400
gene id: 357804:PING_RS16400
uniprot id: A1SZF8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

357804:PING RS01640
gene id: 357804:PING_RS01640
uniprot id: A1SRQ5
names: Cofactor
messages: Can also use Mn(2+) ion.

357804:PING RS04065
gene id: 357804:PING_RS04065
uniprot id: A1ST02
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.
messages: Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

357804:PING RS18825
gene id: 357804:PING_RS18825
uniprot id: A1T0R8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

357804:PING RS06095
gene id: 357804:PING_RS06095
uniprot id: A1SU25
names: Function
names: Similarity
messages: Belongs to the LpxC family.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

357804:PING RS03170
gene id: 357804:PING_RS03170
uniprot id: A1SSI8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. METTL16/RlmF family.
messages: Cytoplasm
messages: Specifically methylates the adenine in position 1618 of 23S rRNA.

357804:PING RS03390
gene id: 357804:PING_RS03390
uniprot id: A1SSN1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.

357804:PING RS18100
gene id: 357804:PING_RS18100
uniprot id: A1SXW4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

357804:PING RS13855
gene id: 357804:PING_RS13855
uniprot id: A1SY29
names: Similarity
messages: Belongs to the class I fructose-bisphosphate aldolase family.

357804:PING RS03025
gene id: 357804:PING_RS03025
uniprot id: A1SSG0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

357804:PING RS00960
gene id: 357804:PING_RS00960
uniprot id: A1SRD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane

357804:PING RS17025
gene id: 357804:PING_RS17025
uniprot id: A1SZS1
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

357804:PING RS18675
gene id: 357804:PING_RS18675
uniprot id: A1T0N8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbA subfamily.
messages: Periplasm

357804:PING RS10975
gene id: 357804:PING_RS10975
uniprot id: A1SWK3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.

357804:PING RS09375
gene id: 357804:PING_RS09375
uniprot id: A1SVR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell inner membrane
messages: Membrane

357804:PING RS04800
gene id: 357804:PING_RS04800
uniprot id: A1STE0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LolB family.
messages: Cell outer membrane
messages: Monomer.
messages: Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein.

357804:PING RS13480
gene id: 357804:PING_RS13480
uniprot id: A1SXW5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

357804:PING RS01695
gene id: 357804:PING_RS01695
uniprot id: A1SRR5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

357804:PING RS00370
gene id: 357804:PING_RS00370
uniprot id: A1SR23
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate.
messages: Cytoplasm

357804:PING RS03180
gene id: 357804:PING_RS03180
uniprot id: A1SSJ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
messages: Homodimer.

357804:PING RS03940
gene id: 357804:PING_RS03940
uniprot id: A1SSY5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrC family.
messages: Cell inner membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

357804:PING RS19215
gene id: 357804:PING_RS19215
uniprot id: A1T0Y8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

357804:PING RS05450
gene id: 357804:PING_RS05450
uniprot id: A1STQ0
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.

357804:PING RS16575
gene id: 357804:PING_RS16575
uniprot id: A1SZI8
names: Function
names: Similarity
names: Subunit
messages: Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters.
messages: Belongs to the transcriptional regulatory Fis family.
messages: Homodimer.

357804:PING RS05480
gene id: 357804:PING_RS05480
uniprot id: A1STQ6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. HutI family.
messages: Binds 1 zinc or iron ion per subunit.
messages: Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate. It is the third step in the universal histidine degradation pathway.
messages: Cytoplasm

357804:PING RS12625
gene id: 357804:PING_RS12625
uniprot id: A1SXG4
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

357804:PING RS08490
gene id: 357804:PING_RS08490
uniprot id: A1SVA6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

357804:PING RS00925
gene id: 357804:PING_RS00925
uniprot id: A1SRC6
names: Function
names: Similarity
messages: Belongs to the HPPK family.
messages: Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.

357804:PING RS03980
gene id: 357804:PING_RS03980
uniprot id: A1SSZ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Catalyzes the deamination of dCTP to dUTP.
messages: Homotrimer.

357804:PING RS01955
gene id: 357804:PING_RS01955
uniprot id: A1SRW5
names: Subcellular Location Annotation
messages: Membrane

357804:PING RS18440
gene id: 357804:PING_RS18440
uniprot id: A1T0J0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgH family.
messages: Cell outer membrane
messages: Membrane
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

357804:PING RS14890
gene id: 357804:PING_RS14890
uniprot id: A1SYM8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptC family.
messages: Cell inner membrane
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptA and the LptBFG transporter complex.
messages: Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA.
messages: Required for the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.

357804:PING RS00735
gene id: 357804:PING_RS00735
uniprot id: A1SR89
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

357804:PING RS03070
gene id: 357804:PING_RS03070
uniprot id: A1SSG8
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

357804:PING RS02015
gene id: 357804:PING_RS02015
uniprot id: A1SRX3
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.

357804:PING RS07600
gene id: 357804:PING_RS07600
uniprot id: A1SUU2
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

357804:PING RS11230
gene id: 357804:PING_RS11230
uniprot id: A1SWQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NapF family.
messages: Could be involved in the maturation of NapA, the catalytic subunit of the periplasmic nitrate reductase, before its export into the periplasm.
messages: Cytoplasm
messages: Interacts with the cytoplasmic NapA precursor.

357804:PING RS00650
gene id: 357804:PING_RS00650
uniprot id: A1SR75
names: Function
names: Similarity
messages: Belongs to the methylglyoxal synthase family.
messages: Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.

357804:PING RS12490
gene id: 357804:PING_RS12490
uniprot id: A1SXD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

357804:PING RS05110
gene id: 357804:PING_RS05110
uniprot id: A1STI4
names: Similarity
messages: Belongs to the peptidase C40 family.

357804:PING RS17960
gene id: 357804:PING_RS17960
uniprot id: A1T093
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

357804:PING RS00470
gene id: 357804:PING_RS00470
uniprot id: A1SR39
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Cytoplasm
messages: Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.

357804:PING RS17845
gene id: 357804:PING_RS17845
uniprot id: A1T071
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

357804:PING RS19145
gene id: 357804:PING_RS19145
uniprot id: A1T0X5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

357804:PING RS07800
gene id: 357804:PING_RS07800
uniprot id: A1SUY2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
messages: Homodimer.

357804:PING RS17665
gene id: 357804:PING_RS17665
uniprot id: A1T037
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. RlmB subfamily.
messages: Cytoplasm
messages: Specifically methylates the ribose of guanosine 2251 in 23S rRNA.

357804:PING RS04855
gene id: 357804:PING_RS04855
uniprot id: A1STF1
names: PTM
names: Subcellular Location Annotation
messages: Activation requires a sequential transfer of a phosphate group from a His in the primary transmitter domain, to an Asp in the receiver domain and to a His in the secondary transmitter domain.
messages: Cell inner membrane

357804:PING RS17480
gene id: 357804:PING_RS17480
uniprot id: A1T006
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

357804:PING RS11275
gene id: 357804:PING_RS11275
uniprot id: A1SWR2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxH family.
messages: Binds 2 Mn(2+) ions per subunit in a binuclear metal center.
messages: Cell inner membrane
messages: Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

357804:PING RS11225
gene id: 357804:PING_RS11225
uniprot id: A1SWQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NapD family.
messages: Chaperone for NapA, the catalytic subunit of the periplasmic nitrate reductase. It binds directly and specifically to the twin-arginine signal peptide of NapA, preventing premature interaction with the Tat translocase and premature export.
messages: Cytoplasm
messages: Interacts with the cytoplasmic NapA precursor.

357804:PING RS09385
gene id: 357804:PING_RS09385
uniprot id: A1SVR2
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

357804:PING RS17905
gene id: 357804:PING_RS17905
uniprot id: A1T082
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

357804:PING RS19095
gene id: 357804:PING_RS19095
uniprot id: A1T0W5
names: Subcellular Location Annotation
messages: Cytoplasm

357804:PING RS16670
gene id: 357804:PING_RS16670
uniprot id: A1SZK6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

357804:PING RS18205
gene id: 357804:PING_RS18205
uniprot id: A1T0E2
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: Methylated by PrmB.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

357804:PING RS09730
gene id: 357804:PING_RS09730
uniprot id: A1SVX8
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.

357804:PING RS15075
gene id: 357804:PING_RS15075
uniprot id: A1SYR2
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

357804:PING RS16330
gene id: 357804:PING_RS16330
uniprot id: A1SZE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

357804:PING RS03385
gene id: 357804:PING_RS03385
uniprot id: A1SSN0
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

357804:PING RS17975
gene id: 357804:PING_RS17975
uniprot id: A1T096
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.

357804:PING RS04270
gene id: 357804:PING_RS04270
uniprot id: A1ST41
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

357804:PING RS15530
gene id: 357804:PING_RS15530
uniprot id: A1SZ01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

357804:PING RS15200
gene id: 357804:PING_RS15200
uniprot id: A1SYT7
names: Activity Regulation
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

357804:PING RS06195
gene id: 357804:PING_RS06195
uniprot id: A1SU43
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

357804:PING RS01635
gene id: 357804:PING_RS01635
uniprot id: A1SRQ4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the malate synthase family. GlcB subfamily.
messages: Cytoplasm
messages: Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

357804:PING RS17885
gene id: 357804:PING_RS17885
uniprot id: A1T078
names: Similarity
messages: Belongs to the ABC transporter superfamily.

357804:PING RS03765
gene id: 357804:PING_RS03765
uniprot id: A1SSV6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

357804:PING RS15120
gene id: 357804:PING_RS15120
uniprot id: A1SYS1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

357804:PING RS02575
gene id: 357804:PING_RS02575
uniprot id: A1SS84
names: Similarity
messages: Belongs to the GSP E family.

357804:PING RS01960
gene id: 357804:PING_RS01960
uniprot id: A1SRW6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

357804:PING RS00450
gene id: 357804:PING_RS00450
uniprot id: A1SR35
names: Similarity
messages: Belongs to the DprA/Smf family.

357804:PING RS05640
gene id: 357804:PING_RS05640
uniprot id: A1STT7
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

357804:PING RS15925
gene id: 357804:PING_RS15925
uniprot id: A1SZ79
names: Subcellular Location Annotation
messages: Membrane

357804:PING RS14195
gene id: 357804:PING_RS14195
uniprot id: A1SY94
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

357804:PING RS15640
gene id: 357804:PING_RS15640
uniprot id: A1SZ23
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DEAD box helicase family. SrmB subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit at low temperature. Exhibits RNA-stimulated ATP hydrolysis and RNA unwinding activity.
messages: Interacts with the 50S ribosomal subunit.

357804:PING RS12155
gene id: 357804:PING_RS12155
uniprot id: A1SX81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial glucokinase family.
messages: Cytoplasm

357804:PING RS07035
gene id: 357804:PING_RS07035
uniprot id: A1SUI7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HscB family.
messages: Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA.
messages: Interacts with HscA and stimulates its ATPase activity.

357804:PING RS18070
gene id: 357804:PING_RS18070
uniprot id: A1T0B5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

357804:PING RS06025
gene id: 357804:PING_RS06025
uniprot id: A1SU11
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

357804:PING RS15570
gene id: 357804:PING_RS15570
uniprot id: A1SZ09
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmC/CycZ/HelC family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

357804:PING RS02450
gene id: 357804:PING_RS02450
uniprot id: A1SS59
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase A chain family.
messages: Cell inner membrane
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

357804:PING RS04550
gene id: 357804:PING_RS04550
uniprot id: A1ST91
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.
messages: Cell membrane
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

357804:PING RS03930
gene id: 357804:PING_RS03930
uniprot id: A1SSY3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NqrA family.
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

357804:PING RS18360
gene id: 357804:PING_RS18360
uniprot id: A1T0H3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.

357804:PING RS03075
gene id: 357804:PING_RS03075
uniprot id: A1SSG9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

357804:PING RS14585
gene id: 357804:PING_RS14585
uniprot id: A1SYG9
names: Cofactor
names: Similarity
messages: Belongs to the RimK family.
messages: Binds 2 magnesium or manganese ions per subunit.

357804:PING RS11535
gene id: 357804:PING_RS11535
uniprot id: A1SWW5
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

357804:PING RS16585
gene id: 357804:PING_RS16585
uniprot id: A1SZJ0
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

357804:PING RS03640
gene id: 357804:PING_RS03640
uniprot id: A1SST0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenine deaminase type 2 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism.

357804:PING RS05590
gene id: 357804:PING_RS05590
uniprot id: A1STS7
names: Similarity
messages: Belongs to the YciI family.

357804:PING RS04330
gene id: 357804:PING_RS04330
uniprot id: A1ST52
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

357804:PING RS04335
gene id: 357804:PING_RS04335
uniprot id: A1ST53
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

357804:PING RS09725
gene id: 357804:PING_RS09725
uniprot id: A1SVX7
names: Similarity
messages: Belongs to the PrpF family.

357804:PING RS04820
gene id: 357804:PING_RS04820
uniprot id: A1STE4
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

357804:PING RS10610
gene id: 357804:PING_RS10610
uniprot id: A1SWD9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

357804:PING RS11140
gene id: 357804:PING_RS11140
uniprot id: A1SWN5
names: Subcellular Location Annotation
messages: Cytoplasm

357804:PING RS17785
gene id: 357804:PING_RS17785
uniprot id: A1T059
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

357804:PING RS15390
gene id: 357804:PING_RS15390
uniprot id: A1SYX4
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

357804:PING RS00695
gene id: 357804:PING_RS00695
uniprot id: A1SR82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

357804:PING RS02115
gene id: 357804:PING_RS02115
uniprot id: A1SRZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptF/LptG family.
messages: Component of the lipopolysaccharide transport and assembly complex. The LptBFG transporter is composed of two ATP-binding proteins (LptB) and two transmembrane proteins (LptF and LptG).
messages: Membrane
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.

357804:PING RS01010
gene id: 357804:PING_RS01010
uniprot id: A1SRE3
names: Function
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 1 subfamily.
messages: Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 2-succinylbenzoate (OSB).

357804:PING RS03255
gene id: 357804:PING_RS03255
uniprot id: A1SSK4
names: Similarity
messages: Belongs to the ABC transporter superfamily.

357804:PING RS03210
gene id: 357804:PING_RS03210
uniprot id: A1SSJ6
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

357804:PING RS15605
gene id: 357804:PING_RS15605
uniprot id: A1SZ16
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

357804:PING RS03760
gene id: 357804:PING_RS03760
uniprot id: A1SSV5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

357804:PING RS14305
gene id: 357804:PING_RS14305
uniprot id: A1SYB3
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

357804:PING RS11735
gene id: 357804:PING_RS11735
uniprot id: A1SX02
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

357804:PING RS09370
gene id: 357804:PING_RS09370
uniprot id: A1SVQ9
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

357804:PING RS03690
gene id: 357804:PING_RS03690
uniprot id: A1SSU0
names: Subcellular Location Annotation
messages: Membrane

357804:PING RS19125
gene id: 357804:PING_RS19125
uniprot id: A1T0X1
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

357804:PING RS17925
gene id: 357804:PING_RS17925
uniprot id: A1T086
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiC family.
messages: Cytoplasm
messages: Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway.

357804:PING RS02330
gene id: 357804:PING_RS02330
uniprot id: A1SS36
names: Subcellular Location Annotation
messages: Membrane

357804:PING RS00500
gene id: 357804:PING_RS00500
uniprot id: A1SR45
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 1 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

357804:PING RS07635
gene id: 357804:PING_RS07635
uniprot id: A1SUU9
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

357804:PING RS12470
gene id: 357804:PING_RS12470
uniprot id: A1SXD3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

357804:PING RS16225
gene id: 357804:PING_RS16225
uniprot id: A1SZC3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial solute-binding protein 7 family.
messages: Homodimer.
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: Periplasm

357804:PING RS18365
gene id: 357804:PING_RS18365
uniprot id: A1T0H4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the calycin superfamily. Lipocalin family.
messages: Cell outer membrane
messages: Homodimer.
messages: Involved in the storage or transport of lipids necessary for membrane maintenance under stressful conditions. Displays a binding preference for lysophospholipids.

357804:PING RS17305
gene id: 357804:PING_RS17305
uniprot id: A1SZX5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homotetramer.

357804:PING RS09950
gene id: 357804:PING_RS09950
uniprot id: A1SW21
names: Subcellular Location Annotation
messages: Membrane

357804:PING RS14850
gene id: 357804:PING_RS14850
uniprot id: A1SYM0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm

357804:PING RS02520
gene id: 357804:PING_RS02520
uniprot id: A1SS73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell inner membrane
messages: Membrane

357804:PING RS10220
gene id: 357804:PING_RS10220
uniprot id: A1SW72
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.

357804:PING RS15085
gene id: 357804:PING_RS15085
uniprot id: A1SYR4
names: Function
names: Subunit
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
messages: Homodimer. Part of the PDH complex, consisting of multiple copies of pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

357804:PING RS00275
gene id: 357804:PING_RS00275
uniprot id: A1SR05
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

357804:PING RS06060
gene id: 357804:PING_RS06060
uniprot id: A1SU18
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. FtsW subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell division.

357804:PING RS05490
gene id: 357804:PING_RS05490
uniprot id: A1STQ8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M32 family.
messages: Binds 1 zinc ion per subunit.
messages: Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues.

357804:PING RS01075
gene id: 357804:PING_RS01075
uniprot id: A1SRF6
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

357804:PING RS05805
gene id: 357804:PING_RS05805
uniprot id: A1STX0
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.

357804:PING RS14925
gene id: 357804:PING_RS14925
uniprot id: A1SYN5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

357804:PING RS06055
gene id: 357804:PING_RS06055
uniprot id: A1SU17
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

357804:PING RS02785
gene id: 357804:PING_RS02785
uniprot id: A1SSB9
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

357804:PING RS12535
gene id: 357804:PING_RS12535
uniprot id: A1SXE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

357804:PING RS17400
gene id: 357804:PING_RS17400
uniprot id: A1SZZ4
names: Similarity
messages: Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily.

357804:PING RS05305
gene id: 357804:PING_RS05305
uniprot id: A1STM2
names: Similarity
messages: Belongs to the DNA photolyase class-1 family.
messages: Belongs to the DNA photolyase family.

357804:PING RS09695
gene id: 357804:PING_RS09695
uniprot id: A1SVX2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

357804:PING RS02865
gene id: 357804:PING_RS02865
uniprot id: A1SSD4
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

357804:PING RS01230
gene id: 357804:PING_RS01230
uniprot id: A1SRI3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.

357804:PING RS11845
gene id: 357804:PING_RS11845
uniprot id: A1SX24
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ZapC family.
messages: Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ.
messages: Cytoplasm
messages: Interacts directly with FtsZ.

357804:PING RS12165
gene id: 357804:PING_RS12165
uniprot id: A1SX83
names: Similarity
messages: Belongs to the pyruvate kinase family.

357804:PING RS02275
gene id: 357804:PING_RS02275
uniprot id: A1SS25
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

357804:PING RS17285
gene id: 357804:PING_RS17285
uniprot id: A1SZX1
names: Similarity
messages: Belongs to the iron-containing alcohol dehydrogenase family.

357804:PING RS15760
gene id: 357804:PING_RS15760
uniprot id: A1SZ48
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

357804:PING RS10640
gene id: 357804:PING_RS10640
uniprot id: A1SWE2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 1 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

357804:PING RS02105
gene id: 357804:PING_RS02105
uniprot id: A1SRZ1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

357804:PING RS06030
gene id: 357804:PING_RS06030
uniprot id: A1SU12
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsL family.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

357804:PING RS14785
gene id: 357804:PING_RS14785
uniprot id: A1SYK8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PNP/UDP phosphorylase family.
messages: Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis.
messages: Cytoplasm

357804:PING RS14840
gene id: 357804:PING_RS14840
uniprot id: A1SYL8
names: Similarity
messages: Belongs to the pyruvate kinase family.

357804:PING RS05625
gene id: 357804:PING_RS05625
uniprot id: A1STT4
names: Cofactor
names: Similarity
messages: Belongs to the anthranilate synthase component I family.
messages: Binds 1 Mg(2+) ion per subunit.

357804:PING RS06350
gene id: 357804:PING_RS06350
uniprot id: A1SU65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

357804:PING RS06630
gene id: 357804:PING_RS06630
uniprot id: A1SUB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CbbQ/NirQ/NorQ/GpvN family.
messages: Vesicle
messages: gas vesicle

357804:PING RS18740
gene id: 357804:PING_RS18740
uniprot id: A1T0Q2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

357804:PING RS18305
gene id: 357804:PING_RS18305
uniprot id: A1T0G2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

357804:PING RS18555
gene id: 357804:PING_RS18555
uniprot id: A1T0L3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

357804:PING RS10215
gene id: 357804:PING_RS10215
uniprot id: A1SW71
names: Function
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.
messages: Functions in two distinct reactions of the de novo folate biosynthetic pathway. Catalyzes the addition of a glutamate residue to dihydropteroate (7,8-dihydropteroate or H2Pte) to form dihydrofolate (7,8-dihydrofolate monoglutamate or H2Pte-Glu). Also catalyzes successive additions of L-glutamate to tetrahydrofolate or 10-formyltetrahydrofolate or 5,10-methylenetetrahydrofolate, leading to folylpolyglutamate derivatives.

357804:PING RS08675
gene id: 357804:PING_RS08675
uniprot id: A1SVD2
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: In the N-terminal section; belongs to the histidinol-phosphatase family.

357804:PING RS01430
gene id: 357804:PING_RS01430
uniprot id: A1SRL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

357804:PING RS00435
gene id: 357804:PING_RS00435
uniprot id: A1SR32
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

357804:PING RS14605
gene id: 357804:PING_RS14605
uniprot id: A1SYH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane

357804:PING RS11835
gene id: 357804:PING_RS11835
uniprot id: A1SX22
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RlmG family.
messages: Cytoplasm
messages: Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA.

357804:PING RS07075
gene id: 357804:PING_RS07075
uniprot id: A1SUJ5
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIS family. GmhA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
messages: Cytoplasm
messages: Homotetramer.
messages: The reaction produces a racemic mixture of D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate.

357804:PING RS04245
gene id: 357804:PING_RS04245
uniprot id: A1ST36
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

357804:PING RS18350
gene id: 357804:PING_RS18350
uniprot id: A1T0H1
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

357804:PING RS03290
gene id: 357804:PING_RS03290
uniprot id: A1SSL1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell inner membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

357804:PING RS04765
gene id: 357804:PING_RS04765
uniprot id: A1STD3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Cell membrane
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

357804:PING RS17100
gene id: 357804:PING_RS17100
uniprot id: A1SZT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

357804:PING RS07215
gene id: 357804:PING_RS07215
uniprot id: A1SUM2
names: Subcellular Location Annotation
messages: Membrane

357804:PING RS09065
gene id: 357804:PING_RS09065
uniprot id: A1SVK2
names: Subcellular Location Annotation
messages: Membrane

357804:PING RS03790
gene id: 357804:PING_RS03790
uniprot id: A1SSW1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbB/TolQ family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

357804:PING RS19330
gene id: 357804:PING_RS19330
uniprot id: A1SS75
names: Subcellular Location Annotation
messages: Cell inner membrane

357804:PING RS17730
gene id: 357804:PING_RS17730
uniprot id: A1T049
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

357804:PING RS06740
gene id: 357804:PING_RS06740
uniprot id: A1SUD9
names: Similarity
messages: Belongs to the threonine synthase family.

357804:PING RS17360
gene id: 357804:PING_RS17360
uniprot id: A1SZY6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

357804:PING RS12040
gene id: 357804:PING_RS12040
uniprot id: A1SX61
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

357804:PING RS07235
gene id: 357804:PING_RS07235
uniprot id: A1SUM5
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

357804:PING RS11930
gene id: 357804:PING_RS11930
uniprot id: A1SX40
names: Similarity
messages: Belongs to the OsmC/Ohr family.

357804:PING RS08705
gene id: 357804:PING_RS08705
uniprot id: A1SVD9
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Homodimer.
messages: Multifunctional regulator of fatty acid metabolism.

357804:PING RS13380
gene id: 357804:PING_RS13380
uniprot id: A1SXU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Membrane

357804:PING RS11600
gene id: 357804:PING_RS11600
uniprot id: A1SWX6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

357804:PING RS17840
gene id: 357804:PING_RS17840
uniprot id: A1T070
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

357804:PING RS08750
gene id: 357804:PING_RS08750
uniprot id: A1SVE8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

357804:PING RS16785
gene id: 357804:PING_RS16785
uniprot id: A1SZM8
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

357804:PING RS16395
gene id: 357804:PING_RS16395
uniprot id: A1SZF7
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

357804:PING RS14315
gene id: 357804:PING_RS14315
uniprot id: A1SYB5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family. QueF type 2 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm
messages: Homodimer.

357804:PING RS17230
gene id: 357804:PING_RS17230
uniprot id: A1SZW0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
messages: Homotetramer.

357804:PING RS14175
gene id: 357804:PING_RS14175
uniprot id: A1SY90
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

357804:PING RS16505
gene id: 357804:PING_RS16505
uniprot id: A1SZH4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NfuA family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is presumably bound at the interface of two monomers.
messages: Homodimer.
messages: Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins.

357804:PING RS15545
gene id: 357804:PING_RS15545
uniprot id: A1SZ04
names: Function
names: Similarity
messages: Belongs to the CcmH/CycL/Ccl2/NrfF family.
messages: Possible subunit of a heme lyase.

357804:PING RS16605
gene id: 357804:PING_RS16605
uniprot id: A1SZJ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.

357804:PING RS03285
gene id: 357804:PING_RS03285
uniprot id: A1SSL0
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. RsmD family.
messages: Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle.

357804:PING RS18525
gene id: 357804:PING_RS18525
uniprot id: A1T0K7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

357804:PING RS05135
gene id: 357804:PING_RS05135
uniprot id: A1STI9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm

357804:PING RS02770
gene id: 357804:PING_RS02770
uniprot id: A1SSB6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

357804:PING RS13015
gene id: 357804:PING_RS13015
uniprot id: A1SXN4
names: Function
names: Subunit
messages: Adenylyltransferase that mediates the addition of adenosine 5'-monophosphate (AMP) to specific residues of target proteins.
messages: Homodimer.

357804:PING RS17455
gene id: 357804:PING_RS17455
uniprot id: A1T001
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

357804:PING RS02845
gene id: 357804:PING_RS02845
uniprot id: A1SSD0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.
messages: Membrane

357804:PING RS17050
gene id: 357804:PING_RS17050
uniprot id: A1SZS6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

357804:PING RS05695
gene id: 357804:PING_RS05695
uniprot id: A1STU8
names: Similarity
messages: Belongs to the UPF0260 family.

357804:PING RS04630
gene id: 357804:PING_RS04630
uniprot id: A1STA7
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

357804:PING RS13090
gene id: 357804:PING_RS13090
uniprot id: A1SXP9
names: Subcellular Location Annotation
messages: Cytoplasm

357804:PING RS03495
gene id: 357804:PING_RS03495
uniprot id: A1SSQ2
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

357804:PING RS10200
gene id: 357804:PING_RS10200
uniprot id: A1SW68
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

357804:PING RS14060
gene id: 357804:PING_RS14060
uniprot id: A1SY69
names: Similarity
messages: Belongs to the DEAD box helicase family.

357804:PING RS08670
gene id: 357804:PING_RS08670
uniprot id: A1SVD1
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

357804:PING RS13415
gene id: 357804:PING_RS13415
uniprot id: A1SXV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell inner membrane
messages: Membrane

357804:PING RS18125
gene id: 357804:PING_RS18125
uniprot id: A1T0C6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

357804:PING RS14455
gene id: 357804:PING_RS14455
uniprot id: A1SYE3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

357804:PING RS14025
gene id: 357804:PING_RS14025
uniprot id: A1SY62
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Binds a copper A center.
messages: Cell membrane
messages: Membrane
messages: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).

357804:PING RS01855
gene id: 357804:PING_RS01855
uniprot id: A1SRU7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.

357804:PING RS19190
gene id: 357804:PING_RS19190
uniprot id: A1T0Y3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

357804:PING RS15635
gene id: 357804:PING_RS15635
uniprot id: A1SZ22
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

357804:PING RS03085
gene id: 357804:PING_RS03085
uniprot id: A1SSH1
names: Function
names: Similarity
messages: Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

357804:PING RS18375
gene id: 357804:PING_RS18375
uniprot id: A1T0H6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FlgA family.
messages: Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly.
messages: Periplasm

357804:PING RS05500
gene id: 357804:PING_RS05500
uniprot id: A1STR0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

357804:PING RS09455
gene id: 357804:PING_RS09455
uniprot id: A1SVS6
names: Subcellular Location Annotation
messages: Membrane

357804:PING RS17915
gene id: 357804:PING_RS17915
uniprot id: A1T084
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RfaH family.
messages: Enhances distal genes transcription elongation in a specialized subset of operons that encode extracytoplasmic components.
messages: Interacts with both the nontemplate DNA and the RNA polymerase (RNAP).

357804:PING RS03065
gene id: 357804:PING_RS03065
uniprot id: A1SSG7
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

357804:PING RS07610
gene id: 357804:PING_RS07610
uniprot id: A1SUU4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

357804:PING RS02985
gene id: 357804:PING_RS02985
uniprot id: A1SSF7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SNF2/RAD54 helicase family. RapA subfamily.
messages: Interacts with the RNAP. Has a higher affinity for the core RNAP than for the holoenzyme. Its ATPase activity is stimulated by binding to RNAP.
messages: Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair.

357804:PING RS05975
gene id: 357804:PING_RS05975
uniprot id: A1SU01
names: Similarity
messages: Belongs to the peptidase U62 family.

357804:PING RS13700
gene id: 357804:PING_RS13700
uniprot id: A1SY01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Membrane

357804:PING RS14725
gene id: 357804:PING_RS14725
uniprot id: A1SYJ6
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family. Prx5 subfamily.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

357804:PING RS13405
gene id: 357804:PING_RS13405
uniprot id: A1SXV0
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.

357804:PING RS11270
gene id: 357804:PING_RS11270
uniprot id: A1SWR1
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

357804:PING RS02430
gene id: 357804:PING_RS02430
uniprot id: A1SS55
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

357804:PING RS10840
gene id: 357804:PING_RS10840
uniprot id: A1SWI1
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.

357804:PING RS08435
gene id: 357804:PING_RS08435
uniprot id: A1SV95
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily.
messages: Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA.
messages: Cytoplasm
messages: Monomer.

357804:PING RS19065
gene id: 357804:PING_RS19065
uniprot id: A1T0V9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EamA transporter family.
messages: Membrane

357804:PING RS01110
gene id: 357804:PING_RS01110
uniprot id: A1SRG2
names: PTM
messages: Binds 2 heme c groups covalently per subunit.

357804:PING RS06730
gene id: 357804:PING_RS06730
uniprot id: A1SUD7
names: Similarity
names: Subunit
messages: Homotetramer.
messages: In the C-terminal section; belongs to the homoserine dehydrogenase family.
messages: In the N-terminal section; belongs to the aspartokinase family.

357804:PING RS16690
gene id: 357804:PING_RS16690
uniprot id: A1SZL0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

357804:PING RS14405
gene id: 357804:PING_RS14405
uniprot id: A1SYD3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

357804:PING RS11815
gene id: 357804:PING_RS11815
uniprot id: A1SX18
names: Similarity
names: Subunit
messages: Belongs to the threonine aldolase family.
messages: Homotetramer.

357804:PING RS08635
gene id: 357804:PING_RS08635
uniprot id: A1SVC4
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the PRA-PH family.
messages: In the N-terminal section; belongs to the PRA-CH family.

357804:PING RS18230
gene id: 357804:PING_RS18230
uniprot id: A1T0E7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

357804:PING RS16775
gene id: 357804:PING_RS16775
uniprot id: A1SZM6
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

357804:PING RS19550
gene id: 357804:PING_RS19550
uniprot id: A1SX43
names: Similarity
messages: Belongs to the ice-binding protein family.

357804:PING RS11010
gene id: 357804:PING_RS11010
uniprot id: A1SWL0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

357804:PING RS14760
gene id: 357804:PING_RS14760
uniprot id: A1SYK3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphopentomutase family.
messages: Binds 1 or 2 manganese ions.
messages: Cytoplasm
messages: Phosphotransfer between the C1 and C5 carbon atoms of pentose.

357804:PING RS01205
gene id: 357804:PING_RS01205
uniprot id: A1SRH8
names: Function
names: Similarity
messages: Belongs to the PEPCase type 1 family.
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.

357804:PING RS15475
gene id: 357804:PING_RS15475
uniprot id: A1SYZ0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

357804:PING RS10685
gene id: 357804:PING_RS10685
uniprot id: A1SWF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

357804:PING RS07460
gene id: 357804:PING_RS07460
uniprot id: A1SUR6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

357804:PING RS11840
gene id: 357804:PING_RS11840
uniprot id: A1SX23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

357804:PING RS11935
gene id: 357804:PING_RS11935
uniprot id: A1SX41
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

357804:PING RS08420
gene id: 357804:PING_RS08420
uniprot id: A1SV92
names: Similarity
messages: Belongs to the UPF0162 family.

357804:PING RS10455
gene id: 357804:PING_RS10455
uniprot id: A1SWB5
names: Cofactor
names: Similarity
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.
messages: Binds 1 zinc ion per subunit.

357804:PING RS14535
gene id: 357804:PING_RS14535
uniprot id: A1SYF9
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

357804:PING RS19270
gene id: 357804:PING_RS19270
uniprot id: A1T0Z9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.

357804:PING RS03955
gene id: 357804:PING_RS03955
uniprot id: A1SSY8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrF family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Cell inner membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Membrane
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway.

357804:PING RS07475
gene id: 357804:PING_RS07475
uniprot id: A1SUR9
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

357804:PING RS18545
gene id: 357804:PING_RS18545
uniprot id: A1T0L1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliP/MopC/SpaP family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a role in the flagellum-specific transport system.

357804:PING RS16835
gene id: 357804:PING_RS16835
uniprot id: A1SZN8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamD family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

357804:PING RS03195
gene id: 357804:PING_RS03195
uniprot id: A1SSJ3
names: Function
names: Similarity
names: Subunit
messages: Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division.
messages: Belongs to the ZapA family. Type 1 subfamily.
messages: Homodimer. Interacts with FtsZ.

357804:PING RS04925
gene id: 357804:PING_RS04925
uniprot id: A1STG3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CcoP / FixP family.
messages: Binds 2 heme C groups per subunit.
messages: C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex.
messages: Cell inner membrane
messages: Component of the cbb3-type cytochrome c oxidase.

357804:PING RS05360
gene id: 357804:PING_RS05360
uniprot id: A1STN3
names: Subcellular Location Annotation
messages: Membrane

357804:PING RS15590
gene id: 357804:PING_RS15590
uniprot id: A1SZ13
names: Similarity
messages: Belongs to the P(II) protein family.

357804:PING RS08740
gene id: 357804:PING_RS08740
uniprot id: A1SVE6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase D family.
messages: Cytoplasm
messages: Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides.

357804:PING RS19045
gene id: 357804:PING_RS19045
uniprot id: A1T0V5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

357804:PING RS02455
gene id: 357804:PING_RS02455
uniprot id: A1SS60
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase C chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

357804:PING RS17085
gene id: 357804:PING_RS17085
uniprot id: A1SZT3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

357804:PING RS18130
gene id: 357804:PING_RS18130
uniprot id: A1T0C7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

357804:PING RS14825
gene id: 357804:PING_RS14825
uniprot id: A1SYL5
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

357804:PING RS17010
gene id: 357804:PING_RS17010
uniprot id: A1SZR8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RraA family.
messages: Cytoplasm
messages: Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome.
messages: Homotrimer. Binds to both RNA-binding sites in the C-terminal region of Rne and to RhlB.

357804:PING RS00330
gene id: 357804:PING_RS00330
uniprot id: A1SR16
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

357804:PING RS00805
gene id: 357804:PING_RS00805
uniprot id: A1SRA2
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

357804:PING RS01785
gene id: 357804:PING_RS01785
uniprot id: A1SRT3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Cell inner membrane
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.

357804:PING RS02765
gene id: 357804:PING_RS02765
uniprot id: A1SSB5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

357804:PING RS13365
gene id: 357804:PING_RS13365
uniprot id: A1SXU2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PstS family.
messages: Involved in the system for phosphate transport across the cytoplasmic membrane.
messages: Periplasm
messages: Secreted

357804:PING RS06130
gene id: 357804:PING_RS06130
uniprot id: A1SU32
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ZapD family.
messages: Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity.
messages: Cytoplasm
messages: Interacts with FtsZ.

357804:PING RS17345
gene id: 357804:PING_RS17345
uniprot id: A1SZY3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

357804:PING RS00605
gene id: 357804:PING_RS00605
uniprot id: A1SR66
names: Similarity
messages: Belongs to the GSP N family.

357804:PING RS17680
gene id: 357804:PING_RS17680
uniprot id: A1T040
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

357804:PING RS02635
gene id: 357804:PING_RS02635
uniprot id: A1SS91
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MutH family.
messages: Cytoplasm
messages: Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair.

357804:PING RS01905
gene id: 357804:PING_RS01905
uniprot id: A1SRV4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MenA family. Type 1 subfamily.
messages: Cell inner membrane
messages: Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).
messages: Membrane

357804:PING RS11425
gene id: 357804:PING_RS11425
uniprot id: A1SWU2
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

357804:PING RS09980
gene id: 357804:PING_RS09980
uniprot id: A1SW27
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

357804:PING RS16685
gene id: 357804:PING_RS16685
uniprot id: A1SZK9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

357804:PING RS12620
gene id: 357804:PING_RS12620
uniprot id: A1SXG3
names: Similarity
messages: Belongs to the Smp family.

357804:PING RS10720
gene id: 357804:PING_RS10720
uniprot id: A1SWF7
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

357804:PING RS00345
gene id: 357804:PING_RS00345
uniprot id: A1SR19
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MetJ family.
messages: Cytoplasm
messages: Homodimer.