35755:UL82 RS03950
gene id: 35755:UL82_RS03950
uniprot id: A0A0F6R001
names: Subcellular Location Annotation
messages: Membrane

35755:UL82 RS04075
gene id: 35755:UL82_RS04075
uniprot id: A0A0F6TDM0
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

35755:UL82 RS07990
gene id: 35755:UL82_RS07990
uniprot id: A0A0F6R1C4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

35755:UL82 RS01315
gene id: 35755:UL82_RS01315
uniprot id: A0A0F6QYD4
names: Function
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 1 subfamily.
messages: Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 2-succinylbenzoate (OSB).

35755:UL82 RS08990
gene id: 35755:UL82_RS08990
uniprot id: A0A0F6R0Y4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

35755:UL82 RS07290
gene id: 35755:UL82_RS07290
uniprot id: A0A0F6TDE4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

35755:UL82 RS08580
gene id: 35755:UL82_RS08580
uniprot id: A0A0F6TDW9
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

35755:UL82 RS06425
gene id: 35755:UL82_RS06425
uniprot id: A0A0F6TD69
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

35755:UL82 RS06090
gene id: 35755:UL82_RS06090
uniprot id: A0A0F6QZY9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

35755:UL82 RS02665
gene id: 35755:UL82_RS02665
uniprot id: A0A0F6R120
names: Subcellular Location Annotation
messages: Membrane

35755:UL82 RS06210
gene id: 35755:UL82_RS06210
uniprot id: A0A0F6TE17
names: Similarity
messages: Belongs to the ribF family.

35755:UL82 RS06255
gene id: 35755:UL82_RS06255
uniprot id: A0A0F6R0R3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

35755:UL82 RS05925
gene id: 35755:UL82_RS05925
uniprot id: A0A0F6TD28
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

35755:UL82 RS09965
gene id: 35755:UL82_RS09965
uniprot id: A0A0F6TEL7
names: Similarity
messages: Belongs to the universal stress protein A family.

35755:UL82 RS07610
gene id: 35755:UL82_RS07610
uniprot id: A0A0F6R176
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type 2 tetrahydrodipicolinate N-succinyltransferase family.
messages: Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA.
messages: Cytoplasm
messages: Homotrimer.

35755:UL82 RS02055
gene id: 35755:UL82_RS02055
uniprot id: A0A0F6QZD1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

35755:UL82 RS05455
gene id: 35755:UL82_RS05455
uniprot id: A0A0F6R1X4
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

35755:UL82 RS09780
gene id: 35755:UL82_RS09780
uniprot id: A0A0F6R1Y2
names: Similarity
messages: Belongs to the UDP-galactopyranose/dTDP-fucopyranose mutase family.

35755:UL82 RS01985
gene id: 35755:UL82_RS01985
uniprot id: A0A0F6QZC2
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

35755:UL82 RS09080
gene id: 35755:UL82_RS09080
uniprot id: A0A0F6R325
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

35755:UL82 RS03750
gene id: 35755:UL82_RS03750
uniprot id: A0A0F6R1E5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF1 family.
messages: Cell membrane

35755:UL82 RS00625
gene id: 35755:UL82_RS00625
uniprot id: A0A0F6QY57
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

35755:UL82 RS01910
gene id: 35755:UL82_RS01910
uniprot id: A0A0F6TCT8
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

35755:UL82 RS02295
gene id: 35755:UL82_RS02295
uniprot id: A0A0F6QZG2
names: Similarity
messages: Belongs to the phosphohexose mutase family.

35755:UL82 RS02430
gene id: 35755:UL82_RS02430
uniprot id: A0A0F6QYQ3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cell surface
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
messages: capsule
messages: cell wall

35755:UL82 RS05460
gene id: 35755:UL82_RS05460
uniprot id: A0A0F6TD37
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

35755:UL82 RS10040
gene id: 35755:UL82_RS10040
uniprot id: A0A0F6TEM2
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

35755:UL82 RS06145
gene id: 35755:UL82_RS06145
uniprot id: A0A0F6R261
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

35755:UL82 RS01545
gene id: 35755:UL82_RS01545
uniprot id: A0A0F6R0N6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

35755:UL82 RS01940
gene id: 35755:UL82_RS01940
uniprot id: A0A0F6QYK3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

35755:UL82 RS00775
gene id: 35755:UL82_RS00775
uniprot id: A0A0F6TCH8
names: Similarity
messages: Belongs to the non-flavoprotein flavin reductase family.

35755:UL82 RS08335
gene id: 35755:UL82_RS08335
uniprot id: A0A0F6TEB2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

35755:UL82 RS07795
gene id: 35755:UL82_RS07795
uniprot id: A0A0F6R2N1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

35755:UL82 RS06900
gene id: 35755:UL82_RS06900
uniprot id: A0A0F6R083
names: Subcellular Location Annotation
messages: Membrane

35755:UL82 RS09890
gene id: 35755:UL82_RS09890
uniprot id: A0A0F6R3A8
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.
messages: Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.

35755:UL82 RS04610
gene id: 35755:UL82_RS04610
uniprot id: A0A0F6R070
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

35755:UL82 RS05215
gene id: 35755:UL82_RS05215
uniprot id: A0A0F6TDH0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the insertion of ferrous iron into coproporphyrin III to form Fe-coproporphyrin III.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

35755:UL82 RS01480
gene id: 35755:UL82_RS01480
uniprot id: A0A0F6TCR0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

35755:UL82 RS03050
gene id: 35755:UL82_RS03050
uniprot id: A0A0F6TCI6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

35755:UL82 RS07135
gene id: 35755:UL82_RS07135
uniprot id: A0A0F6R0A9
names: Similarity
messages: Belongs to the UPF0045 family.

35755:UL82 RS02965
gene id: 35755:UL82_RS02965
uniprot id: A0A0F6TDE8
names: Function
names: Similarity
messages: Belongs to the NrdI family.
messages: Probably involved in ribonucleotide reductase function.

35755:UL82 RS07205
gene id: 35755:UL82_RS07205
uniprot id: A0A0F6R0B7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

35755:UL82 RS06635
gene id: 35755:UL82_RS06635
uniprot id: A0A0F6TDR9
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

35755:UL82 RS08415
gene id: 35755:UL82_RS08415
uniprot id: A0A0F6TDS0
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: Could possibly oxidize fatty acids using specific components.

35755:UL82 RS03175
gene id: 35755:UL82_RS03175
uniprot id: A0A0F6TDG3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-to-5' exoribonuclease specific for small oligoribonucleotides.
messages: Belongs to the oligoribonuclease family.
messages: Cytoplasm

35755:UL82 RS06740
gene id: 35755:UL82_RS06740
uniprot id: A0A0F6R0X6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

35755:UL82 RS05605
gene id: 35755:UL82_RS05605
uniprot id: A0A0F6R1Z4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

35755:UL82 RS03710
gene id: 35755:UL82_RS03710
uniprot id: A0A0F6TDJ7
names: Similarity
messages: Belongs to the dGTPase family. Type 2 subfamily.

35755:UL82 RS03045
gene id: 35755:UL82_RS03045
uniprot id: A0A0F6QZP6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

35755:UL82 RS03335
gene id: 35755:UL82_RS03335
uniprot id: A0A0F6TDH1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

35755:UL82 RS04730
gene id: 35755:UL82_RS04730
uniprot id: A0A0F6TDF9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

35755:UL82 RS09960
gene id: 35755:UL82_RS09960
uniprot id: A0A0F6R202
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

35755:UL82 RS00510
gene id: 35755:UL82_RS00510
uniprot id: A0A0F6QYV3
names: Similarity
messages: Belongs to the amidinotransferase family.

35755:UL82 RS06810
gene id: 35755:UL82_RS06810
uniprot id: A0A0F6TDT4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

35755:UL82 RS05425
gene id: 35755:UL82_RS05425
uniprot id: A0A0F6QZP7
names: Caution
names: Function
names: Similarity
messages: Belongs to the RapZ-like family.
messages: Displays ATPase and GTPase activities.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

35755:UL82 RS05500
gene id: 35755:UL82_RS05500
uniprot id: A0A0F6QZQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

35755:UL82 RS01780
gene id: 35755:UL82_RS01780
uniprot id: A0A0F6QZ98
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

35755:UL82 RS02780
gene id: 35755:UL82_RS02780
uniprot id: A0A0F6TD04
names: Caution
names: Similarity
messages: Belongs to the nitrobindin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Lacks the conserved His residue that binds heme iron in the nitrobindin family.

35755:UL82 RS05510
gene id: 35755:UL82_RS05510
uniprot id: A0A0F6TD02
names: Similarity
messages: Belongs to the OMP decarboxylase family. Type 2 subfamily.

35755:UL82 RS04780
gene id: 35755:UL82_RS04780
uniprot id: A0A0F6TDQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

35755:UL82 RS10210
gene id: 35755:UL82_RS10210
uniprot id: A0A0F6TEY6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

35755:UL82 RS10515
gene id: 35755:UL82_RS10515
uniprot id: A0A0F6R1F2
names: Similarity
messages: Belongs to the ParB family.

35755:UL82 RS02100
gene id: 35755:UL82_RS02100
uniprot id: A0A0F6QZD6
names: Cofactor
names: Similarity
messages: Belongs to the monomeric-type IDH family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

35755:UL82 RS10530
gene id: 35755:UL82_RS10530
uniprot id: A0A0F6R265
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

35755:UL82 RS06230
gene id: 35755:UL82_RS06230
uniprot id: A0A0F6R0R0
names: Subcellular Location Annotation
messages: Membrane

35755:UL82 RS03445
gene id: 35755:UL82_RS03445
uniprot id: A0A0F6R1B4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

35755:UL82 RS05630
gene id: 35755:UL82_RS05630
uniprot id: A0A0F6R1Z7
names: Subcellular Location Annotation
messages: Membrane

35755:UL82 RS05560
gene id: 35755:UL82_RS05560
uniprot id: A0A0F6TDL8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

35755:UL82 RS06855
gene id: 35755:UL82_RS06855
uniprot id: A0A0F6R2C7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

35755:UL82 RS02610
gene id: 35755:UL82_RS02610
uniprot id: A0A0F6R113
names: Function
names: Similarity
messages: Belongs to the trehalose phosphatase family.
messages: Removes the phosphate from trehalose 6-phosphate to produce free trehalose.

35755:UL82 RS03380
gene id: 35755:UL82_RS03380
uniprot id: A0A0F6TD35
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

35755:UL82 RS06840
gene id: 35755:UL82_RS06840
uniprot id: A0A0F6R0Y9
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

35755:UL82 RS05265
gene id: 35755:UL82_RS05265
uniprot id: A0A0F6TD22
names: Similarity
names: Subunit
messages: Belongs to the UPF0210 family.
messages: Homodimer.

35755:UL82 RS10405
gene id: 35755:UL82_RS10405
uniprot id: A0A0F6R249
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

35755:UL82 RS00605
gene id: 35755:UL82_RS00605
uniprot id: A0A0F6R0E6
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
messages: Binds 2 nickel ions per subunit.
messages: Carbamylation allows a single lysine to coordinate two nickel ions.
messages: Carboxylation allows a single lysine to coordinate two nickel ions.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

35755:UL82 RS01560
gene id: 35755:UL82_RS01560
uniprot id: A0A0F6TCT5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

35755:UL82 RS08135
gene id: 35755:UL82_RS08135
uniprot id: A0A0F6TE68
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Monomer.

35755:UL82 RS04030
gene id: 35755:UL82_RS04030
uniprot id: A0A0F6TDB4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

35755:UL82 RS08285
gene id: 35755:UL82_RS08285
uniprot id: A0A0F6TDR3
names: Caution
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

35755:UL82 RS07025
gene id: 35755:UL82_RS07025
uniprot id: A0A0F6R110
names: Function
names: Similarity
messages: Belongs to the CobT family.
messages: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).

35755:UL82 RS00155
gene id: 35755:UL82_RS00155
uniprot id: A0A0F6TCE8
names: Subcellular Location Annotation
messages: Membrane

35755:UL82 RS03770
gene id: 35755:UL82_RS03770
uniprot id: A0A0F6QZ70
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

35755:UL82 RS07940
gene id: 35755:UL82_RS07940
uniprot id: A0A0F6TEJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

35755:UL82 RS03645
gene id: 35755:UL82_RS03645
uniprot id: A0A0F6R1D5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

35755:UL82 RS09880
gene id: 35755:UL82_RS09880
uniprot id: A0A0F6TEW5
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

35755:UL82 RS04725
gene id: 35755:UL82_RS04725
uniprot id: A0A0F6R082
names: Similarity
messages: Belongs to the TlyA family.

35755:UL82 RS09125
gene id: 35755:UL82_RS09125
uniprot id: A0A0F6R0Z6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

35755:UL82 RS11400
gene id: 35755:UL82_RS11400
uniprot id: A0A0F6QZP4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

35755:UL82 RS02470
gene id: 35755:UL82_RS02470
uniprot id: A0A0F6QZI1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

35755:UL82 RS07935
gene id: 35755:UL82_RS07935
uniprot id: A0A0F6R1B8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

35755:UL82 RS03665
gene id: 35755:UL82_RS03665
uniprot id: A0A0F6QZ59
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

35755:UL82 RS01400
gene id: 35755:UL82_RS01400
uniprot id: A0A0F6QYE2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

35755:UL82 RS04280
gene id: 35755:UL82_RS04280
uniprot id: A0A0F6TDA0
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

35755:UL82 RS07230
gene id: 35755:UL82_RS07230
uniprot id: A0A0F6R0C0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

35755:UL82 RS03765
gene id: 35755:UL82_RS03765
uniprot id: A0A0F6TD62
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

35755:UL82 RS07630
gene id: 35755:UL82_RS07630
uniprot id: A0A0F6TED1
names: Cofactor
names: Function
messages: Binds 1 [3Fe-4S] cluster.
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

35755:UL82 RS08110
gene id: 35755:UL82_RS08110
uniprot id: A0A0F6TDQ0
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

35755:UL82 RS05020
gene id: 35755:UL82_RS05020
uniprot id: A0A0F6R1S1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

35755:UL82 RS01660
gene id: 35755:UL82_RS01660
uniprot id: A0A0F6QYH2
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

35755:UL82 RS00020
gene id: 35755:UL82_RS00020
uniprot id: A0A0F6TCP8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

35755:UL82 RS07640
gene id: 35755:UL82_RS07640
uniprot id: A0A0F6TE32
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the MshB deacetylase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deacetylation of 1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway.

35755:UL82 RS06800
gene id: 35755:UL82_RS06800
uniprot id: A0A0F6R072
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

35755:UL82 RS03745
gene id: 35755:UL82_RS03745
uniprot id: A0A0F6QZ67
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

35755:UL82 RS03890
gene id: 35755:UL82_RS03890
uniprot id: A0A0F6R1F9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

35755:UL82 RS05725
gene id: 35755:UL82_RS05725
uniprot id: A0A0F6QZU8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RuvC family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.

35755:UL82 RS07820
gene id: 35755:UL82_RS07820
uniprot id: A0A0F6R2N4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LamB/PxpA family.
messages: Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
messages: Forms a complex composed of PxpA, PxpB and PxpC.

35755:UL82 RS01980
gene id: 35755:UL82_RS01980
uniprot id: A0A0F6TCU4
names: Similarity
messages: Belongs to the IMPDH/GMPR family.

35755:UL82 RS06115
gene id: 35755:UL82_RS06115
uniprot id: A0A0F6QZZ1
names: Subcellular Location Annotation
messages: Membrane

35755:UL82 RS01950
gene id: 35755:UL82_RS01950
uniprot id: A0A0F6TCA9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cell surface
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
messages: capsule
messages: cell wall

35755:UL82 RS05135
gene id: 35755:UL82_RS05135
uniprot id: A0A0F6TD14
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

35755:UL82 RS10545
gene id: 35755:UL82_RS10545
uniprot id: A0A0F6R3F9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

35755:UL82 RS10310
gene id: 35755:UL82_RS10310
uniprot id: A0A0F6TE79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Membrane

35755:UL82 RS10525
gene id: 35755:UL82_RS10525
uniprot id: A0A0F6TEQ7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

35755:UL82 RS03585
gene id: 35755:UL82_RS03585
uniprot id: A0A0F6TDJ0
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

35755:UL82 RS10395
gene id: 35755:UL82_RS10395
uniprot id: A0A0F6R3E8
names: Cofactor
names: Similarity
messages: Belongs to the anthranilate synthase component I family.
messages: Binds 1 Mg(2+) ion per subunit.

35755:UL82 RS04255
gene id: 35755:UL82_RS04255
uniprot id: A0A0F6TCQ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

35755:UL82 RS00280
gene id: 35755:UL82_RS00280
uniprot id: A0A0F6TCF8
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

35755:UL82 RS05575
gene id: 35755:UL82_RS05575
uniprot id: A0A0F6QZR2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm

35755:UL82 RS01380
gene id: 35755:UL82_RS01380
uniprot id: A0A0F6R0L7
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

35755:UL82 RS10490
gene id: 35755:UL82_RS10490
uniprot id: A0A0F6R1E9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

35755:UL82 RS00500
gene id: 35755:UL82_RS00500
uniprot id: A0A0F6R0D3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

35755:UL82 RS08685
gene id: 35755:UL82_RS08685
uniprot id: A0A0F6R0V2
names: Similarity
messages: Belongs to the AccD/PCCB family.

35755:UL82 RS04785
gene id: 35755:UL82_RS04785
uniprot id: A0A0F6QZH6
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

35755:UL82 RS01920
gene id: 35755:UL82_RS01920
uniprot id: A0A0F6R0S4
names: Similarity
messages: Belongs to the AAE transporter (TC 2.A.81) family.

35755:UL82 RS05770
gene id: 35755:UL82_RS05770
uniprot id: A0A0F6TD63
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

35755:UL82 RS03955
gene id: 35755:UL82_RS03955
uniprot id: A0A0F6TDL2
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

35755:UL82 RS03185
gene id: 35755:UL82_RS03185
uniprot id: A0A0F6R190
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

35755:UL82 RS09690
gene id: 35755:UL82_RS09690
uniprot id: A0A0F6TEG3
names: Similarity
messages: Belongs to the AccD/PCCB family.

35755:UL82 RS00915
gene id: 35755:UL82_RS00915
uniprot id: A0A0F6R0H6
names: Similarity
messages: Belongs to the GSP E family.

35755:UL82 RS07190
gene id: 35755:UL82_RS07190
uniprot id: A0A0F6TDW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

35755:UL82 RS01425
gene id: 35755:UL82_RS01425
uniprot id: A0A0F6QYE5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

35755:UL82 RS06815
gene id: 35755:UL82_RS06815
uniprot id: A0A0F6R0Y5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

35755:UL82 RS03410
gene id: 35755:UL82_RS03410
uniprot id: A0A0F6QZ31
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

35755:UL82 RS07265
gene id: 35755:UL82_RS07265
uniprot id: A0A0F6TE97
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

35755:UL82 RS04860
gene id: 35755:UL82_RS04860
uniprot id: A0A0F6R098
names: Function
names: Similarity
messages: Belongs to the NrdI family.
messages: Probably involved in ribonucleotide reductase function.

35755:UL82 RS01085
gene id: 35755:UL82_RS01085
uniprot id: A0A0F6TC53
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

35755:UL82 RS02355
gene id: 35755:UL82_RS02355
uniprot id: A0A0F6QYP6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

35755:UL82 RS03820
gene id: 35755:UL82_RS03820
uniprot id: A0A0F6R1F3
names: Subcellular Location Annotation
messages: Membrane

35755:UL82 RS08895
gene id: 35755:UL82_RS08895
uniprot id: A0A0F6R0X3
names: Function
messages: Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P).

35755:UL82 RS00870
gene id: 35755:UL82_RS00870
uniprot id: A0A0F6TCK7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

35755:UL82 RS10045
gene id: 35755:UL82_RS10045
uniprot id: A0A0F6R208
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

35755:UL82 RS05410
gene id: 35755:UL82_RS05410
uniprot id: A0A0F6TDI6
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

35755:UL82 RS00795
gene id: 35755:UL82_RS00795
uniprot id: A0A0F6QYY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

35755:UL82 RS01650
gene id: 35755:UL82_RS01650
uniprot id: A0A0F6QZ82
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

35755:UL82 RS04875
gene id: 35755:UL82_RS04875
uniprot id: A0A0F6R1Q3
names: Subcellular Location Annotation
messages: Membrane

35755:UL82 RS02210
gene id: 35755:UL82_RS02210
uniprot id: A0A0F6R0W1
names: Similarity
messages: Belongs to the AccD/PCCB family.

35755:UL82 RS05730
gene id: 35755:UL82_RS05730
uniprot id: A0A0F6R225
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

35755:UL82 RS04025
gene id: 35755:UL82_RS04025
uniprot id: A0A0F6R010
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LysE/ArgO transporter (TC 2.A.75) family.
messages: Membrane

35755:UL82 RS02480
gene id: 35755:UL82_RS02480
uniprot id: A0A0F6QYR0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

35755:UL82 RS06405
gene id: 35755:UL82_RS06405
uniprot id: A0A0F6R0T1
names: Similarity
messages: Belongs to the DprA/Smf family.

35755:UL82 RS00050
gene id: 35755:UL82_RS00050
uniprot id: A0A0F6QYN8
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

35755:UL82 RS05175
gene id: 35755:UL82_RS05175
uniprot id: A0A0F6R1U1
names: Subunit
messages: Heterodimer of an alpha and a beta chain.

35755:UL82 RS01225
gene id: 35755:UL82_RS01225
uniprot id: A0A0F6R0K5
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

35755:UL82 RS07420
gene id: 35755:UL82_RS07420
uniprot id: A0A0F6TDK2
names: Subcellular Location Annotation
messages: Membrane

35755:UL82 RS04325
gene id: 35755:UL82_RS04325
uniprot id: A0A0F6R042
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

35755:UL82 RS06180
gene id: 35755:UL82_RS06180
uniprot id: A0A0F6R0Q6
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

35755:UL82 RS01725
gene id: 35755:UL82_RS01725
uniprot id: A0A0F6QZ91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

35755:UL82 RS03055
gene id: 35755:UL82_RS03055
uniprot id: A0A0F6QYX7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

35755:UL82 RS01410
gene id: 35755:UL82_RS01410
uniprot id: A0A0F6TC74
names: Subcellular Location Annotation
messages: Membrane

35755:UL82 RS02440
gene id: 35755:UL82_RS02440
uniprot id: A0A0F6TCE2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.
messages: Homotetramer.
messages: Uses inorganic polyphosphate (polyP) as a donor to convert GDP to GTP or ADP to ATP.

35755:UL82 RS07760
gene id: 35755:UL82_RS07760
uniprot id: A0A0F6TE41
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

35755:UL82 RS06120
gene id: 35755:UL82_RS06120
uniprot id: A0A0F6R260
names: Similarity
messages: Belongs to the PspA/IM30 family.

35755:UL82 RS05415
gene id: 35755:UL82_RS05415
uniprot id: A0A0F6R0G0
names: Function
names: Similarity
messages: Belongs to the WhiA family.
messages: Involved in cell division and chromosome segregation.

35755:UL82 RS04010
gene id: 35755:UL82_RS04010
uniprot id: A0A0F6QZ97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

35755:UL82 RS06835
gene id: 35755:UL82_RS06835
uniprot id: A0A0F6TDV7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

35755:UL82 RS03025
gene id: 35755:UL82_RS03025
uniprot id: A0A0F6TDF3
names: Similarity
messages: Belongs to the peptidase S58 family.

35755:UL82 RS07975
gene id: 35755:UL82_RS07975
uniprot id: A0A0F6R0K4
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

35755:UL82 RS07215
gene id: 35755:UL82_RS07215
uniprot id: A0A0F6TDZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

35755:UL82 RS05420
gene id: 35755:UL82_RS05420
uniprot id: A0A0F6TDV4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gluconeogenesis factor family.
messages: Cytoplasm
messages: Required for morphogenesis under gluconeogenic growth conditions.

35755:UL82 RS03250
gene id: 35755:UL82_RS03250
uniprot id: A0A0F6R196
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

35755:UL82 RS08870
gene id: 35755:UL82_RS08870
uniprot id: A0A0F6R0X1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

35755:UL82 RS09175
gene id: 35755:UL82_RS09175
uniprot id: A0A0F6R335
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.

35755:UL82 RS09455
gene id: 35755:UL82_RS09455
uniprot id: A0A0F6TEI5
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

35755:UL82 RS01640
gene id: 35755:UL82_RS01640
uniprot id: A0A0F6R0P4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

35755:UL82 RS05515
gene id: 35755:UL82_RS05515
uniprot id: A0A0F6R0H3
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

35755:UL82 RS05000
gene id: 35755:UL82_RS05000
uniprot id: A0A0F6TCW1
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

35755:UL82 RS04100
gene id: 35755:UL82_RS04100
uniprot id: A0A0F6TCQ3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 2 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

35755:UL82 RS05245
gene id: 35755:UL82_RS05245
uniprot id: A0A0F6QZM4
names: Subcellular Location Annotation
messages: Membrane

35755:UL82 RS05600
gene id: 35755:UL82_RS05600
uniprot id: A0A0F6QZR5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase MltG family.
messages: Cell membrane
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

35755:UL82 RS02230
gene id: 35755:UL82_RS02230
uniprot id: A0A0F6QYN7
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

35755:UL82 RS09680
gene id: 35755:UL82_RS09680
uniprot id: A0A0F6TE42
names: Similarity
messages: Belongs to the peptidase M1 family.

35755:UL82 RS03265
gene id: 35755:UL82_RS03265
uniprot id: A0A0F6TD57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

35755:UL82 RS10185
gene id: 35755:UL82_RS10185
uniprot id: A0A0F6TE71
names: Similarity
messages: Belongs to the HIBADH-related family.

35755:UL82 RS06340
gene id: 35755:UL82_RS06340
uniprot id: A0A0F6R017
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

35755:UL82 RS02330
gene id: 35755:UL82_RS02330
uniprot id: A0A0F6QYP4
names: Caution
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

35755:UL82 RS06720
gene id: 35755:UL82_RS06720
uniprot id: A0A0F6TD97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EamA transporter family.
messages: Membrane

35755:UL82 RS03825
gene id: 35755:UL82_RS03825
uniprot id: A0A0F6TD67
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

35755:UL82 RS01320
gene id: 35755:UL82_RS01320
uniprot id: A0A0F6R0L2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TPP enzyme family. MenD subfamily.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
messages: Homodimer.

35755:UL82 RS10305
gene id: 35755:UL82_RS10305
uniprot id: A0A0F6R3E1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Membrane

35755:UL82 RS01670
gene id: 35755:UL82_RS01670
uniprot id: A0A0F6TD55
names: Similarity
messages: Belongs to the asparaginase 1 family.

35755:UL82 RS04675
gene id: 35755:UL82_RS04675
uniprot id: A0A0F6QZG5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

35755:UL82 RS06610
gene id: 35755:UL82_RS06610
uniprot id: A0A0F6TD86
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

35755:UL82 RS02870
gene id: 35755:UL82_RS02870
uniprot id: A0A0F6TD08
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

35755:UL82 RS07765
gene id: 35755:UL82_RS07765
uniprot id: A0A0F6R0I0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

35755:UL82 RS07245
gene id: 35755:UL82_RS07245
uniprot id: A0A0F6R137
names: Subcellular Location Annotation
messages: Membrane

35755:UL82 RS06305
gene id: 35755:UL82_RS06305
uniprot id: A0A0F6R0R9
names: Similarity
messages: Belongs to the MQO family.

35755:UL82 RS04910
gene id: 35755:UL82_RS04910
uniprot id: A0A0F6TDR4
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

35755:UL82 RS08925
gene id: 35755:UL82_RS08925
uniprot id: A0A0F6R311
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

35755:UL82 RS05935
gene id: 35755:UL82_RS05935
uniprot id: A0A0F6TD73
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DtxR/MntR family.
messages: Cytoplasm
messages: Homodimer.

35755:UL82 RS00745
gene id: 35755:UL82_RS00745
uniprot id: A0A0F6QYY1
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids lysine, threonine, isoleucine and methionine.

35755:UL82 RS06500
gene id: 35755:UL82_RS06500
uniprot id: A0A0F6TDC3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

35755:UL82 RS04685
gene id: 35755:UL82_RS04685
uniprot id: A0A0F6TCY2
names: Subcellular Location Annotation
messages: Membrane

35755:UL82 RS01530
gene id: 35755:UL82_RS01530
uniprot id: A0A0F6QZ66
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

35755:UL82 RS02360
gene id: 35755:UL82_RS02360
uniprot id: A0A0F6R0Y0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

35755:UL82 RS03810
gene id: 35755:UL82_RS03810
uniprot id: A0A0F6TCS0
names: Similarity
messages: Belongs to the heme oxygenase family.

35755:UL82 RS05180
gene id: 35755:UL82_RS05180
uniprot id: A0A0F6TDJ4
names: Subunit
messages: Heterodimer of an alpha and a beta chain.

35755:UL82 RS04630
gene id: 35755:UL82_RS04630
uniprot id: A0A0F6TDC7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

35755:UL82 RS00840
gene id: 35755:UL82_RS00840
uniprot id: A0A0F6R0G9
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

35755:UL82 RS05185
gene id: 35755:UL82_RS05185
uniprot id: A0A0F6R0D1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Membrane

35755:UL82 RS06860
gene id: 35755:UL82_RS06860
uniprot id: A0A0F6TDF5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

35755:UL82 RS08915
gene id: 35755:UL82_RS08915
uniprot id: A0A0F6TEB6
names: Activity Regulation
names: Caution
names: Function
names: Similarity
messages: Allosterically activated by N-acetylglucosamine 6-phosphate (GlcNAc6P).
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
messages: Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

35755:UL82 RS07810
gene id: 35755:UL82_RS07810
uniprot id: A0A0F6TEE7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

35755:UL82 RS07170
gene id: 35755:UL82_RS07170
uniprot id: A0A0F6R128
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NucS endonuclease family.
messages: Cleaves both 3' and 5' ssDNA extremities of branched DNA structures.
messages: Cytoplasm

35755:UL82 RS01880
gene id: 35755:UL82_RS01880
uniprot id: A0A0F6QZB0
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

35755:UL82 RS02550
gene id: 35755:UL82_RS02550
uniprot id: A0A0F6TD13
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Catalyzes the reversible hydration of carbon dioxide to form bicarbonate.
messages: Reversible hydration of carbon dioxide.

35755:UL82 RS06790
gene id: 35755:UL82_RS06790
uniprot id: A0A0F6R0Y3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SepF family.
messages: Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

35755:UL82 RS00015
gene id: 35755:UL82_RS00015
uniprot id: A0A0F6R061
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

35755:UL82 RS02970
gene id: 35755:UL82_RS02970
uniprot id: A0A0F6QZN5
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

35755:UL82 RS02490
gene id: 35755:UL82_RS02490
uniprot id: A0A0F6TD10
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

35755:UL82 RS05700
gene id: 35755:UL82_RS05700
uniprot id: A0A0F6QZS8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

35755:UL82 RS10115
gene id: 35755:UL82_RS10115
uniprot id: A0A0F6TE30
names: Similarity
messages: Belongs to the FPG family.

35755:UL82 RS03390
gene id: 35755:UL82_RS03390
uniprot id: A0A0F6R1A9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

35755:UL82 RS04095
gene id: 35755:UL82_RS04095
uniprot id: A0A0F6R019
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

35755:UL82 RS07790
gene id: 35755:UL82_RS07790
uniprot id: A0A0F6R0I3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

35755:UL82 RS10265
gene id: 35755:UL82_RS10265
uniprot id: A0A0F6R230
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

35755:UL82 RS08815
gene id: 35755:UL82_RS08815
uniprot id: A0A0F6R302
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

35755:UL82 RS00135
gene id: 35755:UL82_RS00135
uniprot id: A0A0F6QXY6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrgA family.
messages: Cell membrane
messages: Involved in cell division.

35755:UL82 RS04045
gene id: 35755:UL82_RS04045
uniprot id: A0A0F6R013
names: Subcellular Location Annotation
messages: Membrane

35755:UL82 RS09040
gene id: 35755:UL82_RS09040
uniprot id: A0A0F6R1P9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

35755:UL82 RS02465
gene id: 35755:UL82_RS02465
uniprot id: A0A0F6TCY0
names: Similarity
messages: Belongs to the peptidase S13 family.

35755:UL82 RS06475
gene id: 35755:UL82_RS06475
uniprot id: A0A0F6TDS5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

35755:UL82 RS03625
gene id: 35755:UL82_RS03625
uniprot id: A0A0F6TCQ8
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

35755:UL82 RS05895
gene id: 35755:UL82_RS05895
uniprot id: A0A0F6R238
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

35755:UL82 RS09205
gene id: 35755:UL82_RS09205
uniprot id: A0A0F6TDX0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

35755:UL82 RS03720
gene id: 35755:UL82_RS03720
uniprot id: A0A0F6R1E3
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

35755:UL82 RS07430
gene id: 35755:UL82_RS07430
uniprot id: A0A0F6R2I7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. DeaD/CsdA subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation.

35755:UL82 RS07095
gene id: 35755:UL82_RS07095
uniprot id: A0A0F6R2F4
names: Similarity
messages: Belongs to the glutamine synthetase family.

35755:UL82 RS10005
gene id: 35755:UL82_RS10005
uniprot id: A0A0F6TE59
names: Similarity
messages: Belongs to the PspA/IM30 family.

35755:UL82 RS01840
gene id: 35755:UL82_RS01840
uniprot id: A0A0F6QYJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S8 family.
messages: Cell membrane
messages: Membrane

35755:UL82 RS02730
gene id: 35755:UL82_RS02730
uniprot id: A0A0F6TDD5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

35755:UL82 RS07520
gene id: 35755:UL82_RS07520
uniprot id: A0A0F6TE20
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

35755:UL82 RS04585
gene id: 35755:UL82_RS04585
uniprot id: A0A0F6R068
names: Subcellular Location Annotation
messages: Membrane

35755:UL82 RS02620
gene id: 35755:UL82_RS02620
uniprot id: A0A0F6QZJ4
names: Similarity
messages: Belongs to the glycosyltransferase 20 family.

35755:UL82 RS05355
gene id: 35755:UL82_RS05355
uniprot id: A0A0F6R1W1
names: Subcellular Location Annotation
messages: Membrane

35755:UL82 RS04825
gene id: 35755:UL82_RS04825
uniprot id: A0A0F6R1P5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

35755:UL82 RS02595
gene id: 35755:UL82_RS02595
uniprot id: A0A0F6QZJ2
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.

35755:UL82 RS06390
gene id: 35755:UL82_RS06390
uniprot id: A0A0F6R023
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

35755:UL82 RS09025
gene id: 35755:UL82_RS09025
uniprot id: A0A0F6R0Y6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

35755:UL82 RS09295
gene id: 35755:UL82_RS09295
uniprot id: A0A0F6TEE2
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

35755:UL82 RS06525
gene id: 35755:UL82_RS06525
uniprot id: A0A0F6TE43
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

35755:UL82 RS08080
gene id: 35755:UL82_RS08080
uniprot id: A0A0F6R1D4
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

35755:UL82 RS03395
gene id: 35755:UL82_RS03395
uniprot id: A0A0F6TDH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

35755:UL82 RS03290
gene id: 35755:UL82_RS03290
uniprot id: A0A0F6TCP2
names: Similarity
messages: Belongs to the peptidase M1 family.

35755:UL82 RS00620
gene id: 35755:UL82_RS00620
uniprot id: A0A0F6TBY1
names: Subcellular Location Annotation
messages: Membrane

35755:UL82 RS02940
gene id: 35755:UL82_RS02940
uniprot id: A0A0F6TCL8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
messages: Homodimer.

35755:UL82 RS05080
gene id: 35755:UL82_RS05080
uniprot id: A0A0F6R0C3
names: Similarity
messages: Belongs to the formate--tetrahydrofolate ligase family.

35755:UL82 RS10010
gene id: 35755:UL82_RS10010
uniprot id: A0A0F6R186
names: Similarity
messages: Belongs to the thioredoxin family.

35755:UL82 RS06765
gene id: 35755:UL82_RS06765
uniprot id: A0A0F6R0X9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

35755:UL82 RS07220
gene id: 35755:UL82_RS07220
uniprot id: A0A0F6R134
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

35755:UL82 RS05650
gene id: 35755:UL82_RS05650
uniprot id: A0A0F6QZS1
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

35755:UL82 RS05390
gene id: 35755:UL82_RS05390
uniprot id: A0A0F6R0F6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Membrane

35755:UL82 RS03515
gene id: 35755:UL82_RS03515
uniprot id: A0A0F6QZ42
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

35755:UL82 RS04555
gene id: 35755:UL82_RS04555
uniprot id: A0A0F6TCX1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

35755:UL82 RS06190
gene id: 35755:UL82_RS06190
uniprot id: A0A0F6QZZ9
names: Subcellular Location Annotation
messages: Membrane

35755:UL82 RS01535
gene id: 35755:UL82_RS01535
uniprot id: A0A0F6TCR3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

35755:UL82 RS01460
gene id: 35755:UL82_RS01460
uniprot id: A0A0F6TC78
names: Subcellular Location Annotation
messages: Membrane

35755:UL82 RS09400
gene id: 35755:UL82_RS09400
uniprot id: A0A0F6TDY2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate.
messages: Homotrimer.

35755:UL82 RS07890
gene id: 35755:UL82_RS07890
uniprot id: A0A0F6R0J6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl-inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics.
messages: Belongs to the MshB deacetylase family. Mca subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Monomer.

35755:UL82 RS03180
gene id: 35755:UL82_RS03180
uniprot id: A0A0F6QZ07
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

35755:UL82 RS05395
gene id: 35755:UL82_RS05395
uniprot id: A0A0F6TD32
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PEPCase type 1 family.
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
messages: Homotetramer.

35755:UL82 RS00495
gene id: 35755:UL82_RS00495
uniprot id: A0A0F6QY25
names: Similarity
messages: Belongs to the arginine deiminase family.

35755:UL82 RS00705
gene id: 35755:UL82_RS00705
uniprot id: A0A0F6QY66
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

35755:UL82 RS11290
gene id: 35755:UL82_RS11290
uniprot id: A0A0F6TE36
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

35755:UL82 RS05260
gene id: 35755:UL82_RS05260
uniprot id: A0A0F6R0D9
names: Similarity
messages: Belongs to the UPF0237 family.

35755:UL82 RS09850
gene id: 35755:UL82_RS09850
uniprot id: A0A0F6TE14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

35755:UL82 RS09865
gene id: 35755:UL82_RS09865
uniprot id: A0A0F6R173
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by fructose 1,6-bisphosphate (FBP).
messages: Belongs to the LDH/MDH superfamily. LDH family.
messages: Catalyzes the conversion of lactate to pyruvate.
messages: Cytoplasm
messages: Homotetramer.

35755:UL82 RS09685
gene id: 35755:UL82_RS09685
uniprot id: A0A0F6R1X0
names: Similarity
messages: Belongs to the peptidase C15 family.

35755:UL82 RS02725
gene id: 35755:UL82_RS02725
uniprot id: A0A0F6QZK8
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

35755:UL82 RS08655
gene id: 35755:UL82_RS08655
uniprot id: A0A0F6TEA0
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF2.
messages: Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.

35755:UL82 RS03430
gene id: 35755:UL82_RS03430
uniprot id: A0A0F6TCP9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

35755:UL82 RS06015
gene id: 35755:UL82_RS06015
uniprot id: A0A0F6QZY0
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

35755:UL82 RS09005
gene id: 35755:UL82_RS09005
uniprot id: A0A0F6R1P6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

35755:UL82 RS03340
gene id: 35755:UL82_RS03340
uniprot id: A0A0F6QZ22
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

35755:UL82 RS05120
gene id: 35755:UL82_RS05120
uniprot id: A0A0F6R1T4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MshC subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent condensation of GlcN-Ins and L-cysteine to form L-Cys-GlcN-Ins.
messages: Monomer.

35755:UL82 RS05530
gene id: 35755:UL82_RS05530
uniprot id: A0A0F6R1Y4
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

35755:UL82 RS09380
gene id: 35755:UL82_RS09380
uniprot id: A0A0F6R124
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

35755:UL82 RS02755
gene id: 35755:UL82_RS02755
uniprot id: A0A0F6TCG6
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

35755:UL82 RS06785
gene id: 35755:UL82_RS06785
uniprot id: A0A0F6TDA2
names: Similarity
messages: Belongs to the YggT family.

35755:UL82 RS07295
gene id: 35755:UL82_RS07295
uniprot id: A0A0F6R143
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

35755:UL82 RS08315
gene id: 35755:UL82_RS08315
uniprot id: A0A0F6R1I0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

35755:UL82 RS08875
gene id: 35755:UL82_RS08875
uniprot id: A0A0F6R307
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

35755:UL82 RS06995
gene id: 35755:UL82_RS06995
uniprot id: A0A0F6TDG7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase bacterial subunit CtaF family.
messages: Cell membrane
messages: Membrane
messages: Part of cytochrome c oxidase, its function is unknown.

35755:UL82 RS00585
gene id: 35755:UL82_RS00585
uniprot id: A0A0F6TCG1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UreD family.
messages: Cytoplasm
messages: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
messages: UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

35755:UL82 RS06485
gene id: 35755:UL82_RS06485
uniprot id: A0A0F6TD75
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

35755:UL82 RS01550
gene id: 35755:UL82_RS01550
uniprot id: A0A0F6TD45
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

35755:UL82 RS01160
gene id: 35755:UL82_RS01160
uniprot id: A0A0F6TCK8
names: Function
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

35755:UL82 RS02675
gene id: 35755:UL82_RS02675
uniprot id: A0A0F6QZK1
names: Subcellular Location Annotation
messages: Membrane

35755:UL82 RS01335
gene id: 35755:UL82_RS01335
uniprot id: A0A0F6TC69
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).

35755:UL82 RS07235
gene id: 35755:UL82_RS07235
uniprot id: A0A0F6R2G7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

35755:UL82 RS08115
gene id: 35755:UL82_RS08115
uniprot id: A0A0F6R0L6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

35755:UL82 RS05655
gene id: 35755:UL82_RS05655
uniprot id: A0A0F6R200
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

35755:UL82 RS01285
gene id: 35755:UL82_RS01285
uniprot id: A0A0F6QZ35
names: Subcellular Location Annotation
messages: Membrane

35755:UL82 RS00765
gene id: 35755:UL82_RS00765
uniprot id: A0A0F6TC28
names: Similarity
messages: Belongs to the catalase family.

35755:UL82 RS05990
gene id: 35755:UL82_RS05990
uniprot id: A0A0F6QZX7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

35755:UL82 RS03990
gene id: 35755:UL82_RS03990
uniprot id: A0A0F6R1G6
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

35755:UL82 RS08475
gene id: 35755:UL82_RS08475
uniprot id: A0A0F6TDS3
names: Similarity
messages: Belongs to the transglycosylase family. Rpf subfamily.

35755:UL82 RS01760
gene id: 35755:UL82_RS01760
uniprot id: A0A0F6QYI3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

35755:UL82 RS03160
gene id: 35755:UL82_RS03160
uniprot id: A0A0F6TD23
names: Similarity
messages: Belongs to the DapA family.

35755:UL82 RS01860
gene id: 35755:UL82_RS01860
uniprot id: A0A0F6TD70
names: Similarity
messages: Belongs to the WXG100 family.

35755:UL82 RS03350
gene id: 35755:UL82_RS03350
uniprot id: A0A0F6TD61
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

35755:UL82 RS01755
gene id: 35755:UL82_RS01755
uniprot id: A0A0F6TC98
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

35755:UL82 RS06215
gene id: 35755:UL82_RS06215
uniprot id: A0A0F6R002
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

35755:UL82 RS08060
gene id: 35755:UL82_RS08060
uniprot id: A0A0F6TDT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

35755:UL82 RS01715
gene id: 35755:UL82_RS01715
uniprot id: A0A0F6R0Q0
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

35755:UL82 RS08450
gene id: 35755:UL82_RS08450
uniprot id: A0A0F6TEM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Membrane

35755:UL82 RS06825
gene id: 35755:UL82_RS06825
uniprot id: A0A0F6R075
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

35755:UL82 RS06375
gene id: 35755:UL82_RS06375
uniprot id: A0A0F6TDB1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

35755:UL82 RS03495
gene id: 35755:UL82_RS03495
uniprot id: A0A0F6R1C0
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

35755:UL82 RS01825
gene id: 35755:UL82_RS01825
uniprot id: A0A0F6TCA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

35755:UL82 RS08280
gene id: 35755:UL82_RS08280
uniprot id: A0A0F6R2V5
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

35755:UL82 RS06700
gene id: 35755:UL82_RS06700
uniprot id: A0A0F6R0W9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
messages: Homotetramer.

35755:UL82 RS07405
gene id: 35755:UL82_RS07405
uniprot id: A0A0F6R0D5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

35755:UL82 RS02005
gene id: 35755:UL82_RS02005
uniprot id: A0A0F6TCX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

35755:UL82 RS01235
gene id: 35755:UL82_RS01235
uniprot id: A0A0F6QZ29
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

35755:UL82 RS00545
gene id: 35755:UL82_RS00545
uniprot id: A0A0F6QY50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

35755:UL82 RS06520
gene id: 35755:UL82_RS06520
uniprot id: A0A0F6R298
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

35755:UL82 RS05045
gene id: 35755:UL82_RS05045
uniprot id: A0A0F6R1S4
names: Caution
names: Domain
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic ubiquitin-like protein family.
messages: Is modified by deamidation of its C-terminal glutamine to glutamate by the deamidase Dop, a prerequisite to the subsequent pupylation process.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation.
messages: Strongly interacts with the proteasome-associated ATPase ARC through a hydrophobic interface; the interacting region of Pup lies in its C-terminal half. There is one Pup binding site per ARC hexamer ring.
messages: The N-terminal unstructured half of Pup provides a signal required to initiate unfolding and degradation by the proteasome but is not needed for pupylation, while the C-terminal helical half of Pup interacts with ARC to target proteins to the proteasome.

35755:UL82 RS10200
gene id: 35755:UL82_RS10200
uniprot id: A0A0F6R1B0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

35755:UL82 RS09070
gene id: 35755:UL82_RS09070
uniprot id: A0A0F6TEG2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

35755:UL82 RS03835
gene id: 35755:UL82_RS03835
uniprot id: A0A0F6QZ78
names: Subcellular Location Annotation
messages: Membrane

35755:UL82 RS06775
gene id: 35755:UL82_RS06775
uniprot id: A0A0F6R069
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DivIVA family.
messages: Cytoplasm

35755:UL82 RS09225
gene id: 35755:UL82_RS09225
uniprot id: A0A0F6R348
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Cu-Zn superoxide dismutase family.
messages: Binds 1 copper ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems. May play a role in favoring mycobacterial survival in phagocytes.

35755:UL82 RS05200
gene id: 35755:UL82_RS05200
uniprot id: A0A0F6R1U4
names: Subcellular Location Annotation
messages: Membrane

35755:UL82 RS01300
gene id: 35755:UL82_RS01300
uniprot id: A0A0F6TCZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MenA family. Type 1 subfamily.
messages: Cell membrane
messages: Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).
messages: Membrane

35755:UL82 RS06200
gene id: 35755:UL82_RS06200
uniprot id: A0A0F6TDN8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

35755:UL82 RS00670
gene id: 35755:UL82_RS00670
uniprot id: A0A0F6QYX2
names: Subcellular Location Annotation
messages: Membrane

35755:UL82 RS06245
gene id: 35755:UL82_RS06245
uniprot id: A0A0F6R273
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

35755:UL82 RS00710
gene id: 35755:UL82_RS00710
uniprot id: A0A0F6R0F7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CobB/CobQ family. GatD subfamily.
messages: Forms a heterodimer with MurT.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The GatD subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia. The resulting ammonia molecule is channeled to the active site of MurT.

35755:UL82 RS01785
gene id: 35755:UL82_RS01785
uniprot id: A0A0F6TCS9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

35755:UL82 RS05585
gene id: 35755:UL82_RS05585
uniprot id: A0A0F6TD46
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

35755:UL82 RS05775
gene id: 35755:UL82_RS05775
uniprot id: A0A0F6QZV7
names: Similarity
messages: Belongs to the DyP-type peroxidase family.

35755:UL82 RS10315
gene id: 35755:UL82_RS10315
uniprot id: A0A0F6R237
names: Subcellular Location Annotation
messages: Membrane

35755:UL82 RS02735
gene id: 35755:UL82_RS02735
uniprot id: A0A0F6QYU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0073 (Hly-III) family.
messages: Membrane

35755:UL82 RS03660
gene id: 35755:UL82_RS03660
uniprot id: A0A0F6TD85
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

35755:UL82 RS00695
gene id: 35755:UL82_RS00695
uniprot id: A0A0F6QYX5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

35755:UL82 RS07900
gene id: 35755:UL82_RS07900
uniprot id: A0A0F6TDN3
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

35755:UL82 RS04615
gene id: 35755:UL82_RS04615
uniprot id: A0A0F6TCX5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

35755:UL82 RS07665
gene id: 35755:UL82_RS07665
uniprot id: A0A0F6TDL9
names: Similarity
messages: Belongs to the ArsC family.

35755:UL82 RS08720
gene id: 35755:UL82_RS08720
uniprot id: A0A0F6TEA5
names: Subcellular Location Annotation
messages: Membrane

35755:UL82 RS06515
gene id: 35755:UL82_RS06515
uniprot id: A0A0F6R037
names: Similarity
messages: Belongs to the acylphosphatase family.

35755:UL82 RS01645
gene id: 35755:UL82_RS01645
uniprot id: A0A0F6TCC8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

35755:UL82 RS08820
gene id: 35755:UL82_RS08820
uniprot id: A0A0F6TDU4
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

35755:UL82 RS04145
gene id: 35755:UL82_RS04145
uniprot id: A0A0F6TDC1
names: Subcellular Location Annotation
messages: Secreted

35755:UL82 RS05065
gene id: 35755:UL82_RS05065
uniprot id: A0A0F6QZK3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM61 family.
messages: Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA.
messages: Homotetramer composed of a dimer of dimers.

35755:UL82 RS08490
gene id: 35755:UL82_RS08490
uniprot id: A0A0F6TDW6
names: Similarity
messages: Belongs to the helicase family. RAD25/XPB subfamily.

35755:UL82 RS00190
gene id: 35755:UL82_RS00190
uniprot id: A0A0F6R084
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

35755:UL82 RS05565
gene id: 35755:UL82_RS05565
uniprot id: A0A0F6R0I1
names: Similarity
messages: Belongs to the peptidase M24B family.

35755:UL82 RS01540
gene id: 35755:UL82_RS01540
uniprot id: A0A0F6QYF9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

35755:UL82 RS10385
gene id: 35755:UL82_RS10385
uniprot id: A0A0F6TEZ8
names: Subcellular Location Annotation
messages: Membrane

35755:UL82 RS10110
gene id: 35755:UL82_RS10110
uniprot id: A0A0F6R3C7
names: Function
names: Similarity
messages: Belongs to the TrhO family.
messages: Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.

35755:UL82 RS07225
gene id: 35755:UL82_RS07225
uniprot id: A0A0F6TDD8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

35755:UL82 RS03165
gene id: 35755:UL82_RS03165
uniprot id: A0A0F6QZS3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

35755:UL82 RS09055
gene id: 35755:UL82_RS09055
uniprot id: A0A0F6R322
names: Function
names: Similarity
messages: ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
messages: Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.

35755:UL82 RS01395
gene id: 35755:UL82_RS01395
uniprot id: A0A0F6TC43
names: Similarity
messages: Belongs to the carotenoid/retinoid oxidoreductase family.

35755:UL82 RS01795
gene id: 35755:UL82_RS01795
uniprot id: A0A0F6R0Q8
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

35755:UL82 RS02195
gene id: 35755:UL82_RS02195
uniprot id: A0A0F6QZE9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

35755:UL82 RS00005
gene id: 35755:UL82_RS00005
uniprot id: A0A0F6QXX0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

35755:UL82 RS03300
gene id: 35755:UL82_RS03300
uniprot id: A0A0F6R1A0
names: Similarity
messages: Belongs to the LacAB/RpiB family.

35755:UL82 RS00920
gene id: 35755:UL82_RS00920
uniprot id: A0A0F6TCW3
names: Subcellular Location Annotation
messages: Membrane

35755:UL82 RS05590
gene id: 35755:UL82_RS05590
uniprot id: A0A0F6R0I4
names: Similarity
messages: Belongs to the peptidase A24 family.

35755:UL82 RS02265
gene id: 35755:UL82_RS02265
uniprot id: A0A0F6TCH3
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

35755:UL82 RS06280
gene id: 35755:UL82_RS06280
uniprot id: A0A0F6R0R6
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

35755:UL82 RS00885
gene id: 35755:UL82_RS00885
uniprot id: A0A0F6QY86
names: Subcellular Location Annotation
messages: Membrane

35755:UL82 RS03425
gene id: 35755:UL82_RS03425
uniprot id: A0A0F6QZU2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

35755:UL82 RS05085
gene id: 35755:UL82_RS05085
uniprot id: A0A0F6TDG2
names: Similarity
messages: Belongs to the class-II fumarase/aspartase family. Aspartase subfamily.

35755:UL82 RS06545
gene id: 35755:UL82_RS06545
uniprot id: A0A0F6R2A1
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

35755:UL82 RS04980
gene id: 35755:UL82_RS04980
uniprot id: A0A0F6R0B3
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

35755:UL82 RS07545
gene id: 35755:UL82_RS07545
uniprot id: A0A0F6TDL0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.

35755:UL82 RS08245
gene id: 35755:UL82_RS08245
uniprot id: A0A0F6R2U9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

35755:UL82 RS00800
gene id: 35755:UL82_RS00800
uniprot id: A0A0F6TCK2
names: Subcellular Location Annotation
messages: Membrane

35755:UL82 RS03360
gene id: 35755:UL82_RS03360
uniprot id: A0A0F6TCK5
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 2 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

35755:UL82 RS02760
gene id: 35755:UL82_RS02760
uniprot id: A0A0F6QYU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

35755:UL82 RS07300
gene id: 35755:UL82_RS07300
uniprot id: A0A0F6TDJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lactate permease family.
messages: Cell membrane
messages: Membrane
messages: Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate.

35755:UL82 RS03090
gene id: 35755:UL82_RS03090
uniprot id: A0A0F6R182
names: Similarity
names: Subunit
messages: Belongs to the glutaminase family.
messages: Homotetramer.

35755:UL82 RS01600
gene id: 35755:UL82_RS01600
uniprot id: A0A0F6QZ76
names: Subcellular Location Annotation
messages: Membrane

35755:UL82 RS05535
gene id: 35755:UL82_RS05535
uniprot id: A0A0F6TDJ6
names: Function
names: Similarity
messages: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
messages: Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines.

35755:UL82 RS06575
gene id: 35755:UL82_RS06575
uniprot id: A0A0F6TDR2
names: Similarity
names: Subunit
messages: Belongs to the pyruvate kinase family.
messages: Homotetramer.

35755:UL82 RS04120
gene id: 35755:UL82_RS04120
uniprot id: A0A0F6R022
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

35755:UL82 RS06985
gene id: 35755:UL82_RS06985
uniprot id: A0A0F6R2E2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

35755:UL82 RS08420
gene id: 35755:UL82_RS08420
uniprot id: A0A0F6R1I9
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

35755:UL82 RS00630
gene id: 35755:UL82_RS00630
uniprot id: A0A0F6R0E8
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

35755:UL82 RS06370
gene id: 35755:UL82_RS06370
uniprot id: A0A0F6R284
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

35755:UL82 RS05965
gene id: 35755:UL82_RS05965
uniprot id: A0A0F6QZX5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

35755:UL82 RS04755
gene id: 35755:UL82_RS04755
uniprot id: A0A0F6TCY6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

35755:UL82 RS00445
gene id: 35755:UL82_RS00445
uniprot id: A0A0F6R0B5
names: Subcellular Location Annotation
messages: Membrane

35755:UL82 RS06165
gene id: 35755:UL82_RS06165
uniprot id: A0A0F6QZZ6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

35755:UL82 RS01455
gene id: 35755:UL82_RS01455
uniprot id: A0A0F6R0M6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

35755:UL82 RS07650
gene id: 35755:UL82_RS07650
uniprot id: A0A0F6R2L3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

35755:UL82 RS04975
gene id: 35755:UL82_RS04975
uniprot id: A0A0F6TDR8
names: Similarity
messages: Belongs to the CobH/CbiC family.

35755:UL82 RS06925
gene id: 35755:UL82_RS06925
uniprot id: A0A0F6R086
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

35755:UL82 RS09770
gene id: 35755:UL82_RS09770
uniprot id: A0A0F6R3A0
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

35755:UL82 RS10360
gene id: 35755:UL82_RS10360
uniprot id: A0A0F6R243
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

35755:UL82 RS03670
gene id: 35755:UL82_RS03670
uniprot id: A0A0F6R1D7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

35755:UL82 RS05690
gene id: 35755:UL82_RS05690
uniprot id: A0A0F6R0J8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

35755:UL82 RS01945
gene id: 35755:UL82_RS01945
uniprot id: A0A0F6R0S7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

35755:UL82 RS10165
gene id: 35755:UL82_RS10165
uniprot id: A0A0F6R218
names: Subcellular Location Annotation
messages: Membrane

35755:UL82 RS07280
gene id: 35755:UL82_RS07280
uniprot id: A0A0F6R0C4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

35755:UL82 RS04345
gene id: 35755:UL82_RS04345
uniprot id: A0A0F6TDA6
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family.

35755:UL82 RS07040
gene id: 35755:UL82_RS07040
uniprot id: A0A0F6R2E7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

35755:UL82 RS10345
gene id: 35755:UL82_RS10345
uniprot id: A0A0F6R1C9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

35755:UL82 RS08880
gene id: 35755:UL82_RS08880
uniprot id: A0A0F6TEF0
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

35755:UL82 RS00590
gene id: 35755:UL82_RS00590
uniprot id: A0A0F6QYW4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
messages: Cytoplasm
messages: Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
messages: Homodimer. UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

35755:UL82 RS01975
gene id: 35755:UL82_RS01975
uniprot id: A0A0F6R0T0
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

35755:UL82 RS06345
gene id: 35755:UL82_RS06345
uniprot id: A0A0F6R281
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

35755:UL82 RS06910
gene id: 35755:UL82_RS06910
uniprot id: A0A0F6TDB3
names: Cofactor
names: Function
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Exonuclease that cleaves single-stranded 3' overhangs of double-stranded RNA.
messages: Homodimer.

35755:UL82 RS04540
gene id: 35755:UL82_RS04540
uniprot id: A0A0F6TCS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

35755:UL82 RS01620
gene id: 35755:UL82_RS01620
uniprot id: A0A0F6TCU0
names: Similarity
messages: Belongs to the pirin family.

35755:UL82 RS05960
gene id: 35755:UL82_RS05960
uniprot id: A0A0F6TDZ4
names: Subcellular Location Annotation
messages: Cytoplasm

35755:UL82 RS04215
gene id: 35755:UL82_RS04215
uniprot id: A0A0F6TDM7
names: Similarity
messages: In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.
messages: In the central section; belongs to the CRISPR-associated helicase Cas3 family.

35755:UL82 RS08020
gene id: 35755:UL82_RS08020
uniprot id: A0A0F6R1C8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

35755:UL82 RS04735
gene id: 35755:UL82_RS04735
uniprot id: A0A0F6QZH0
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

35755:UL82 RS01810
gene id: 35755:UL82_RS01810
uniprot id: A0A0F6TCV9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

35755:UL82 RS01625
gene id: 35755:UL82_RS01625
uniprot id: A0A0F6QZ79
names: Similarity
messages: Belongs to the glycosyl hydrolase 32 family.

35755:UL82 RS00310
gene id: 35755:UL82_RS00310
uniprot id: A0A0F6QY03
names: Similarity
messages: Belongs to the peptidase M13 family.

35755:UL82 RS01705
gene id: 35755:UL82_RS01705
uniprot id: A0A0F6TCD1
names: Similarity
messages: Belongs to the AAE transporter (TC 2.A.81) family.

35755:UL82 RS05475
gene id: 35755:UL82_RS05475
uniprot id: A0A0F6QZQ2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

35755:UL82 RS03575
gene id: 35755:UL82_RS03575
uniprot id: A0A0F6TD48
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IPP isomerase type 1 family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium ion binds only when substrate is bound.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).
messages: Cytoplasm

35755:UL82 RS01885
gene id: 35755:UL82_RS01885
uniprot id: A0A0F6TCA5
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

35755:UL82 RS10355
gene id: 35755:UL82_RS10355
uniprot id: A0A0F6TE44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

35755:UL82 RS10270
gene id: 35755:UL82_RS10270
uniprot id: A0A0F6TEY9
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

35755:UL82 RS06630
gene id: 35755:UL82_RS06630
uniprot id: A0A0F6R0V9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

35755:UL82 RS07535
gene id: 35755:UL82_RS07535
uniprot id: A0A0F6TDG6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

35755:UL82 RS10465
gene id: 35755:UL82_RS10465
uniprot id: A0A0F6R1E6
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

35755:UL82 RS03620
gene id: 35755:UL82_RS03620
uniprot id: A0A0F6R1D2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

35755:UL82 RS04070
gene id: 35755:UL82_RS04070
uniprot id: A0A0F6R015
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

35755:UL82 RS01385
gene id: 35755:UL82_RS01385
uniprot id: A0A0F6TCP3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

35755:UL82 RS04660
gene id: 35755:UL82_RS04660
uniprot id: A0A0F6TDF4
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

35755:UL82 RS02245
gene id: 35755:UL82_RS02245
uniprot id: A0A0F6QZF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

35755:UL82 RS09300
gene id: 35755:UL82_RS09300
uniprot id: A0A0F6R116
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

35755:UL82 RS02815
gene id: 35755:UL82_RS02815
uniprot id: A0A0F6R139
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

35755:UL82 RS03680
gene id: 35755:UL82_RS03680
uniprot id: A0A0F6QZW8
names: Similarity
messages: Belongs to the Fur family.

35755:UL82 RS08095
gene id: 35755:UL82_RS08095
uniprot id: A0A0F6R2S1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.
messages: Homotetramer.
messages: Uses inorganic polyphosphate (polyP) as a donor to convert GDP to GTP or ADP to ATP.

35755:UL82 RS06755
gene id: 35755:UL82_RS06755
uniprot id: A0A0F6R2B7
names: Similarity
messages: Belongs to the asparaginase 1 family.

35755:UL82 RS05625
gene id: 35755:UL82_RS05625
uniprot id: A0A0F6QZR7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.

35755:UL82 RS05330
gene id: 35755:UL82_RS05330
uniprot id: A0A0F6R1V8
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

35755:UL82 RS02960
gene id: 35755:UL82_RS02960
uniprot id: A0A0F6R153
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Electron transport system for the ribonucleotide reductase system NrdEF.

35755:UL82 RS02855
gene id: 35755:UL82_RS02855
uniprot id: A0A0F6TCL4
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

35755:UL82 RS05370
gene id: 35755:UL82_RS05370
uniprot id: A0A0F6TDK7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 2 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

35755:UL82 RS05955
gene id: 35755:UL82_RS05955
uniprot id: A0A0F6R0N7
names: Function
names: Similarity
names: Subunit
messages: Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity.
messages: Belongs to the AhpD family.
messages: Homotrimer.

35755:UL82 RS09150
gene id: 35755:UL82_RS09150
uniprot id: A0A0F6R0Z9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

35755:UL82 RS06160
gene id: 35755:UL82_RS06160
uniprot id: A0A0F6TDQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

35755:UL82 RS04355
gene id: 35755:UL82_RS04355
uniprot id: A0A0F6TDN6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

35755:UL82 RS01675
gene id: 35755:UL82_RS01675
uniprot id: A0A0F6QZ85
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

35755:UL82 RS05465
gene id: 35755:UL82_RS05465
uniprot id: A0A0F6R0G6
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

35755:UL82 RS06095
gene id: 35755:UL82_RS06095
uniprot id: A0A0F6R257
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

35755:UL82 RS01955
gene id: 35755:UL82_RS01955
uniprot id: A0A0F6QZB9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

35755:UL82 RS02585
gene id: 35755:UL82_RS02585
uniprot id: A0A0F6R109
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

35755:UL82 RS03560
gene id: 35755:UL82_RS03560
uniprot id: A0A0F6TCQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the branched chain amino acid transporter family.
messages: Cell membrane
messages: Component of the transport system for branched-chain amino acids.
messages: Membrane

35755:UL82 RS09335
gene id: 35755:UL82_RS09335
uniprot id: A0A0F6R357
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane

35755:UL82 RS10125
gene id: 35755:UL82_RS10125
uniprot id: A0A0F6TE67
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.

35755:UL82 RS09665
gene id: 35755:UL82_RS09665
uniprot id: A0A0F6TE00
names: Subcellular Location Annotation
messages: Membrane

35755:UL82 RS01775
gene id: 35755:UL82_RS01775
uniprot id: A0A0F6TCD6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

35755:UL82 RS03420
gene id: 35755:UL82_RS03420
uniprot id: A0A0F6TCL1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

35755:UL82 RS00980
gene id: 35755:UL82_RS00980
uniprot id: A0A0F6TCW9
names: Similarity
messages: Belongs to the adenylyl cyclase class-3 family.

35755:UL82 RS01575
gene id: 35755:UL82_RS01575
uniprot id: A0A0F6TC85
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

35755:UL82 RS03755
gene id: 35755:UL82_RS03755
uniprot id: A0A0F6TCR5
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

35755:UL82 RS07260
gene id: 35755:UL82_RS07260
uniprot id: A0A0F6R2G8
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

35755:UL82 RS05140
gene id: 35755:UL82_RS05140
uniprot id: A0A0F6QZL2
names: Similarity
messages: Belongs to the UPF0098 family.

35755:UL82 RS03590
gene id: 35755:UL82_RS03590
uniprot id: A0A0F6QZ50
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

35755:UL82 RS02805
gene id: 35755:UL82_RS02805
uniprot id: A0A0F6TD29
names: Similarity
messages: Belongs to the cytochrome P450 family.

35755:UL82 RS06640
gene id: 35755:UL82_RS06640
uniprot id: A0A0F6R052
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

35755:UL82 RS05365
gene id: 35755:UL82_RS05365
uniprot id: A0A0F6R0F3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

35755:UL82 RS11405
gene id: 35755:UL82_RS11405
uniprot id: A0A0F6R1W7
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

35755:UL82 RS02560
gene id: 35755:UL82_RS02560
uniprot id: A0A0F6R106
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

35755:UL82 RS09395
gene id: 35755:UL82_RS09395
uniprot id: A0A0F6R1T9
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

35755:UL82 RS01100
gene id: 35755:UL82_RS01100
uniprot id: A0A0F6TCK3
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

35755:UL82 RS07690
gene id: 35755:UL82_RS07690
uniprot id: A0A0F6TED6
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

35755:UL82 RS01490
gene id: 35755:UL82_RS01490
uniprot id: A0A0F6TD40
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

35755:UL82 RS05320
gene id: 35755:UL82_RS05320
uniprot id: A0A0F6TCY5
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

35755:UL82 RS07005
gene id: 35755:UL82_RS07005
uniprot id: A0A0F6TDV1
names: Similarity
messages: Belongs to the asparagine synthetase family.

35755:UL82 RS08555
gene id: 35755:UL82_RS08555
uniprot id: A0A0F6TEC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

35755:UL82 RS06270
gene id: 35755:UL82_RS06270
uniprot id: A0A0F6R274
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

35755:UL82 RS03345
gene id: 35755:UL82_RS03345
uniprot id: A0A0F6R1A3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

35755:UL82 RS05440
gene id: 35755:UL82_RS05440
uniprot id: A0A0F6R0G3
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

35755:UL82 RS01800
gene id: 35755:UL82_RS01800
uniprot id: A0A0F6TD65
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

35755:UL82 RS00195
gene id: 35755:UL82_RS00195
uniprot id: A0A0F6TCC7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.

35755:UL82 RS05525
gene id: 35755:UL82_RS05525
uniprot id: A0A0F6QZQ7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

35755:UL82 RS08640
gene id: 35755:UL82_RS08640
uniprot id: A0A0F6R2Y6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

35755:UL82 RS06685
gene id: 35755:UL82_RS06685
uniprot id: A0A0F6R058
names: Similarity
messages: Belongs to the HSP15 family.

35755:UL82 RS02800
gene id: 35755:UL82_RS02800
uniprot id: A0A0F6QZL9
names: Similarity
messages: Belongs to the Dps family.

35755:UL82 RS06135
gene id: 35755:UL82_RS06135
uniprot id: A0A0F6TDN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

35755:UL82 RS06620
gene id: 35755:UL82_RS06620
uniprot id: A0A0F6R2A6
names: Subcellular Location Annotation
messages: Membrane

35755:UL82 RS06510
gene id: 35755:UL82_RS06510
uniprot id: A0A0F6TDQ8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

35755:UL82 RS04595
gene id: 35755:UL82_RS04595
uniprot id: A0A0F6QZF6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

35755:UL82 RS04005
gene id: 35755:UL82_RS04005
uniprot id: A0A0F6TD82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

35755:UL82 RS01345
gene id: 35755:UL82_RS01345
uniprot id: A0A0F6TCM5
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

35755:UL82 RS02910
gene id: 35755:UL82_RS02910
uniprot id: A0A0F6TD34
names: Similarity
messages: Belongs to the phosphohexose mutase family.

35755:UL82 RS00805
gene id: 35755:UL82_RS00805
uniprot id: A0A0F6QY77
names: Subcellular Location Annotation
messages: Membrane

35755:UL82 RS09750
gene id: 35755:UL82_RS09750
uniprot id: A0A0F6TEG7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DtxR/MntR family.
messages: Cytoplasm
messages: Homodimer.

35755:UL82 RS01405
gene id: 35755:UL82_RS01405
uniprot id: A0A0F6R0L9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

35755:UL82 RS03715
gene id: 35755:UL82_RS03715
uniprot id: A0A0F6QZ65
names: Similarity
messages: Belongs to the ribonuclease N1/T1 family.

35755:UL82 RS03005
gene id: 35755:UL82_RS03005
uniprot id: A0A0F6QYX1
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

35755:UL82 RS00235
gene id: 35755:UL82_RS00235
uniprot id: A0A0F6QXZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 87 family.
messages: Membrane

35755:UL82 RS06240
gene id: 35755:UL82_RS06240
uniprot id: A0A0F6R005
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

35755:UL82 RS00715
gene id: 35755:UL82_RS00715
uniprot id: A0A0F6TCH2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MurCDEF family. MurT subfamily.
messages: Forms a heterodimer with GatD.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The MurT subunit catalyzes the ATP-dependent amidation of D-glutamate residue of lipid II, converting it to an isoglutamine residue.

35755:UL82 RS02905
gene id: 35755:UL82_RS02905
uniprot id: A0A0F6R147
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

35755:UL82 RS01375
gene id: 35755:UL82_RS01375
uniprot id: A0A0F6QYD9
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

35755:UL82 RS05610
gene id: 35755:UL82_RS05610
uniprot id: A0A0F6TDW7
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

35755:UL82 RS09610
gene id: 35755:UL82_RS09610
uniprot id: A0A0F6R1W3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

35755:UL82 RS07705
gene id: 35755:UL82_RS07705
uniprot id: A0A0F6TE37
names: Subcellular Location Annotation
messages: Membrane

35755:UL82 RS01570
gene id: 35755:UL82_RS01570
uniprot id: A0A0F6R0N8
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

35755:UL82 RS02015
gene id: 35755:UL82_RS02015
uniprot id: A0A0F6TCB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NlpA lipoprotein family.
messages: Membrane

35755:UL82 RS05470
gene id: 35755:UL82_RS05470
uniprot id: A0A0F6TDJ1
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

35755:UL82 RS01790
gene id: 35755:UL82_RS01790
uniprot id: A0A0F6QYI6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

35755:UL82 RS08800
gene id: 35755:UL82_RS08800
uniprot id: A0A0F6R1M3
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

35755:UL82 RS05040
gene id: 35755:UL82_RS05040
uniprot id: A0A0F6QZJ9
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the Pup ligase/Pup deamidase family. Pup-conjugating enzyme subfamily.
messages: Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine.
messages: The reaction mechanism probably proceeds via the activation of Pup by phosphorylation of its C-terminal glutamate, which is then subject to nucleophilic attack by the substrate lysine, resulting in an isopeptide bond and the release of phosphate as a good leaving group.

35755:UL82 RS00610
gene id: 35755:UL82_RS00610
uniprot id: A0A0F6TCI4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease beta subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

35755:UL82 RS00975
gene id: 35755:UL82_RS00975
uniprot id: A0A0F6QYZ9
names: Subcellular Location Annotation
messages: Membrane

35755:UL82 RS09085
gene id: 35755:UL82_RS09085
uniprot id: A0A0F6TDW1
names: Subcellular Location Annotation
messages: Membrane

35755:UL82 RS08070
gene id: 35755:UL82_RS08070
uniprot id: A0A0F6R2R8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

35755:UL82 RS08645
gene id: 35755:UL82_RS08645
uniprot id: A0A0F6TDX5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in cellular division.

35755:UL82 RS03980
gene id: 35755:UL82_RS03980
uniprot id: A0A0F6TCP7
names: Subcellular Location Annotation
messages: Membrane

35755:UL82 RS06170
gene id: 35755:UL82_RS06170
uniprot id: A0A0F6R264
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidylate synthase ThyX family.
messages: Binds 4 FAD per tetramer. Each FAD binding site is formed by three monomers.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

35755:UL82 RS06380
gene id: 35755:UL82_RS06380
uniprot id: A0A0F6R0S8
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

35755:UL82 RS06795
gene id: 35755:UL82_RS06795
uniprot id: A0A0F6TDF0
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

35755:UL82 RS07200
gene id: 35755:UL82_RS07200
uniprot id: A0A0F6TE91
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

35755:UL82 RS05055
gene id: 35755:UL82_RS05055
uniprot id: A0A0F6R0C1
names: Similarity
names: Subunit
messages: Belongs to the AAA ATPase family.
messages: Homohexamer. Assembles into a hexameric ring structure.

35755:UL82 RS01050
gene id: 35755:UL82_RS01050
uniprot id: A0A0F6QZ08
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

35755:UL82 RS00730
gene id: 35755:UL82_RS00730
uniprot id: A0A0F6QY69
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homotetramer.

35755:UL82 RS03985
gene id: 35755:UL82_RS03985
uniprot id: A0A0F6QZ94
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

35755:UL82 RS05480
gene id: 35755:UL82_RS05480
uniprot id: A0A0F6R1X7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

35755:UL82 RS00575
gene id: 35755:UL82_RS00575
uniprot id: A0A0F6R0E4
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

35755:UL82 RS05715
gene id: 35755:UL82_RS05715
uniprot id: A0A0F6R0L4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

35755:UL82 RS09135
gene id: 35755:UL82_RS09135
uniprot id: A0A0F6TEG5
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

35755:UL82 RS03530
gene id: 35755:UL82_RS03530
uniprot id: A0A0F6QZV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

35755:UL82 RS04250
gene id: 35755:UL82_RS04250
uniprot id: A0A0F6R033
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

35755:UL82 RS10410
gene id: 35755:UL82_RS10410
uniprot id: A0A0F6TE48
names: Function
names: Similarity
messages: Belongs to the TrpC family.
messages: Belongs to the TrpF family.
messages: Bifunctional enzyme that catalyzes two sequential steps of tryptophan biosynthetic pathway. The first reaction is catalyzed by the isomerase, coded by the TrpF domain; the second reaction is catalyzed by the synthase, coded by the TrpC domain.
messages: In the C-terminal section; belongs to the TrpF family.
messages: In the N-terminal section; belongs to the TrpC family.

35755:UL82 RS08665
gene id: 35755:UL82_RS08665
uniprot id: A0A0F6R2Y8
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

35755:UL82 RS05665
gene id: 35755:UL82_RS05665
uniprot id: A0A0F6R0J4
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the peroxiredoxin family. Tpx subfamily.
messages: Homodimer.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this atypical 2-Cys peroxiredoxin, C(R) is present in the same subunit to form an intramolecular disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

35755:UL82 RS01685
gene id: 35755:UL82_RS01685
uniprot id: A0A0F6QYH5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

35755:UL82 RS06435
gene id: 35755:UL82_RS06435
uniprot id: A0A0F6TDB6
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

35755:UL82 RS05980
gene id: 35755:UL82_RS05980
uniprot id: A0A0F6R0N9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

35755:UL82 RS03630
gene id: 35755:UL82_RS03630
uniprot id: A0A0F6QZW2
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

35755:UL82 RS10495
gene id: 35755:UL82_RS10495
uniprot id: A0A0F6R3F4
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

35755:UL82 RS08065
gene id: 35755:UL82_RS08065
uniprot id: A0A0F6R0L0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

35755:UL82 RS08180
gene id: 35755:UL82_RS08180
uniprot id: A0A0F6R1E8
names: Similarity
messages: Belongs to the UDPGP type 2 family.

35755:UL82 RS09755
gene id: 35755:UL82_RS09755
uniprot id: A0A0F6R1X9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

35755:UL82 RS09785
gene id: 35755:UL82_RS09785
uniprot id: A0A0F6TE08
names: Similarity
messages: Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family.

35755:UL82 RS01865
gene id: 35755:UL82_RS01865
uniprot id: A0A0F6QYJ5
names: Similarity
messages: Belongs to the WXG100 family.

35755:UL82 RS08905
gene id: 35755:UL82_RS08905
uniprot id: A0A0F6TDZ1
names: Similarity
messages: Belongs to the DapA family.

35755:UL82 RS06285
gene id: 35755:UL82_RS06285
uniprot id: A0A0F6TDR1
names: Domain
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the CobB/CbiA family.
messages: Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L-glutamine or ammonia as the nitrogen source.
messages: Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP and hydrogenobyrinate and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.
messages: The a and c carboxylates of hydrogenobyrinate are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CobB catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate.

35755:UL82 RS03520
gene id: 35755:UL82_RS03520
uniprot id: A0A0F6R1C2
names: Similarity
messages: Belongs to the peptidase S33 family.

35755:UL82 RS10170
gene id: 35755:UL82_RS10170
uniprot id: A0A0F6TE34
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

35755:UL82 RS03555
gene id: 35755:UL82_RS03555
uniprot id: A0A0F6QZV3
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

35755:UL82 RS03845
gene id: 35755:UL82_RS03845
uniprot id: A0A0F6TD99
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgE subfamily.
messages: Homodimer.
messages: Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1->4)-glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB.

35755:UL82 RS00330
gene id: 35755:UL82_RS00330
uniprot id: A0A0F6QY06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 85 family.
messages: Cell membrane
messages: Membrane

35755:UL82 RS06325
gene id: 35755:UL82_RS06325
uniprot id: A0A0F6TDP7
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.

35755:UL82 RS03730
gene id: 35755:UL82_RS03730
uniprot id: A0A0F6QZX3
names: Function
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

35755:UL82 RS09670
gene id: 35755:UL82_RS09670
uniprot id: A0A0F6R154
names: Subcellular Location Annotation
messages: Membrane

35755:UL82 RS05485
gene id: 35755:UL82_RS05485
uniprot id: A0A0F6TDV9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

35755:UL82 RS07140
gene id: 35755:UL82_RS07140
uniprot id: A0A0F6R2F9
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

35755:UL82 RS03690
gene id: 35755:UL82_RS03690
uniprot id: A0A0F6QZ61
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm
messages: Homodimer.

35755:UL82 RS00565
gene id: 35755:UL82_RS00565
uniprot id: A0A0F6TC13
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

35755:UL82 RS09190
gene id: 35755:UL82_RS09190
uniprot id: A0A0F6TEG9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

35755:UL82 RS01565
gene id: 35755:UL82_RS01565
uniprot id: A0A0F6QYG2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

35755:UL82 RS01690
gene id: 35755:UL82_RS01690
uniprot id: A0A0F6R0P8
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

35755:UL82 RS04065
gene id: 35755:UL82_RS04065
uniprot id: A0A0F6TD87
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

35755:UL82 RS01820
gene id: 35755:UL82_RS01820
uniprot id: A0A0F6R0R1
names: Similarity
messages: Belongs to the CsoR family.

35755:UL82 RS07615
gene id: 35755:UL82_RS07615
uniprot id: A0A0F6TE07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family.
messages: Membrane

35755:UL82 RS09365
gene id: 35755:UL82_RS09365
uniprot id: A0A0F6TEE4
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

35755:UL82 RS00955
gene id: 35755:UL82_RS00955
uniprot id: A0A0F6TC42
names: Subcellular Location Annotation
messages: Cytoplasm

35755:UL82 RS02710
gene id: 35755:UL82_RS02710
uniprot id: A0A0F6QYU1
names: Similarity
messages: Belongs to the SAICAR synthetase family.

35755:UL82 RS00365
gene id: 35755:UL82_RS00365
uniprot id: A0A0F6TBZ4
names: Similarity
messages: Belongs to the ABC transporter superfamily.

35755:UL82 RS06495
gene id: 35755:UL82_RS06495
uniprot id: A0A0F6R295
names: Similarity
messages: Belongs to the P(II) protein family.

35755:UL82 RS02590
gene id: 35755:UL82_RS02590
uniprot id: A0A0F6TCZ1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

35755:UL82 RS00760
gene id: 35755:UL82_RS00760
uniprot id: A0A0F6R0G1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

35755:UL82 RS06570
gene id: 35755:UL82_RS06570
uniprot id: A0A0F6R2A3
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

35755:UL82 RS01695
gene id: 35755:UL82_RS01695
uniprot id: A0A0F6TC94
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

35755:UL82 RS01370
gene id: 35755:UL82_RS01370
uniprot id: A0A0F6TCZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

35755:UL82 RS05720
gene id: 35755:UL82_RS05720
uniprot id: A0A0F6TDK9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

35755:UL82 RS01190
gene id: 35755:UL82_RS01190
uniprot id: A0A0F6QYC0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

35755:UL82 RS02980
gene id: 35755:UL82_RS02980
uniprot id: A0A0F6QYW6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
messages: Tetramer of two alpha and two beta subunits.

35755:UL82 RS00615
gene id: 35755:UL82_RS00615
uniprot id: A0A0F6QYW7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease gamma subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

35755:UL82 RS02975
gene id: 35755:UL82_RS02975
uniprot id: A0A0F6TD38
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

35755:UL82 RS06010
gene id: 35755:UL82_RS06010
uniprot id: A0A0F6TDM5
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

35755:UL82 RS04665
gene id: 35755:UL82_RS04665
uniprot id: A0A0F6R076
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Homodimer.

35755:UL82 RS06830
gene id: 35755:UL82_RS06830
uniprot id: A0A0F6R2C5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

35755:UL82 RS04050
gene id: 35755:UL82_RS04050
uniprot id: A0A0F6TCT7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

35755:UL82 RS08175
gene id: 35755:UL82_RS08175
uniprot id: A0A0F6TDQ4
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

35755:UL82 RS02530
gene id: 35755:UL82_RS02530
uniprot id: A0A0F6QYR9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

35755:UL82 RS05930
gene id: 35755:UL82_RS05930
uniprot id: A0A0F6R0N5
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

35755:UL82 RS01730
gene id: 35755:UL82_RS01730
uniprot id: A0A0F6TD60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

35755:UL82 RS03505
gene id: 35755:UL82_RS03505
uniprot id: A0A0F6QZU9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

35755:UL82 RS05445
gene id: 35755:UL82_RS05445
uniprot id: A0A0F6TCZ6
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

35755:UL82 RS00370
gene id: 35755:UL82_RS00370
uniprot id: A0A0F6QYS2
names: Subcellular Location Annotation
messages: Membrane

35755:UL82 RS00755
gene id: 35755:UL82_RS00755
uniprot id: A0A0F6QY72
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

35755:UL82 RS10245
gene id: 35755:UL82_RS10245
uniprot id: A0A0F6TE74
names: Similarity
messages: Belongs to the gluconokinase GntK/GntV family.

35755:UL82 RS05315
gene id: 35755:UL82_RS05315
uniprot id: A0A0F6R0E5
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.

35755:UL82 RS02395
gene id: 35755:UL82_RS02395
uniprot id: A0A0F6QZH4
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

35755:UL82 RS09045
gene id: 35755:UL82_RS09045
uniprot id: A0A0F6TEC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

35755:UL82 RS00030
gene id: 35755:UL82_RS00030
uniprot id: A0A0F6TCD8
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

35755:UL82 RS08120
gene id: 35755:UL82_RS08120
uniprot id: A0A0F6R2S3
names: Similarity
messages: Belongs to the transglycosylase family. Rpf subfamily.

35755:UL82 RS01500
gene id: 35755:UL82_RS01500
uniprot id: A0A0F6R0N1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

35755:UL82 RS00505
gene id: 35755:UL82_RS00505
uniprot id: A0A0F6TC06
names: Similarity
messages: Belongs to the carbamate kinase family.

35755:UL82 RS01055
gene id: 35755:UL82_RS01055
uniprot id: A0A0F6TCM2
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

35755:UL82 RS00600
gene id: 35755:UL82_RS00600
uniprot id: A0A0F6QY54
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UreE family.
messages: Cytoplasm
messages: Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly.

35755:UL82 RS09805
gene id: 35755:UL82_RS09805
uniprot id: A0A0F6R1Y5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.

35755:UL82 RS09275
gene id: 35755:UL82_RS09275
uniprot id: A0A0F6R114
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

35755:UL82 RS03260
gene id: 35755:UL82_RS03260
uniprot id: A0A0F6QZT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

35755:UL82 RS04575
gene id: 35755:UL82_RS04575
uniprot id: A0A0F6R1L9
names: Similarity
messages: Belongs to the universal stress protein A family.

35755:UL82 RS06140
gene id: 35755:UL82_RS06140
uniprot id: A0A0F6QZZ4
names: Similarity
messages: Belongs to the YciI family.

35755:UL82 RS04635
gene id: 35755:UL82_RS04635
uniprot id: A0A0F6R073
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

35755:UL82 RS08585
gene id: 35755:UL82_RS08585
uniprot id: A0A0F6R0U1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

35755:UL82 RS10680
gene id: 35755:UL82_RS10680
uniprot id: A0A0F6TEQ4
names: Subcellular Location Annotation
messages: Membrane

35755:UL82 RS03635
gene id: 35755:UL82_RS03635
uniprot id: A0A0F6TD54
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

35755:UL82 RS06695
gene id: 35755:UL82_RS06695
uniprot id: A0A0F6TDS4
names: Similarity
messages: Belongs to the IMPACT family.

35755:UL82 RS05855
gene id: 35755:UL82_RS05855
uniprot id: A0A0F6TD24
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

35755:UL82 RS05095
gene id: 35755:UL82_RS05095
uniprot id: A0A0F6R1T1
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Feedback inhibited by histidine.

35755:UL82 RS02145
gene id: 35755:UL82_RS02145
uniprot id: A0A0F6QZE3
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

35755:UL82 RS07685
gene id: 35755:UL82_RS07685
uniprot id: A0A0F6R184
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

35755:UL82 RS06975
gene id: 35755:UL82_RS06975
uniprot id: A0A0F6TDB9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Cell membrane
messages: Iron-sulfur subunit of the cytochrome bc1 complex, an essential component of the respiratory electron transport chain required for ATP synthesis. The bc1 complex catalyzes the oxidation of menaquinol and the reduction of cytochrome c in the respiratory chain. The bc1 complex operates through a Q-cycle mechanism that couples electron transfer to generation of the proton gradient that drives ATP synthesis.
messages: Membrane

35755:UL82 RS01520
gene id: 35755:UL82_RS01520
uniprot id: A0A0F6R0N4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

35755:UL82 RS07075
gene id: 35755:UL82_RS07075
uniprot id: A0A0F6TDV8
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

35755:UL82 RS01655
gene id: 35755:UL82_RS01655
uniprot id: A0A0F6TCS2
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

35755:UL82 RS00925
gene id: 35755:UL82_RS00925
uniprot id: A0A0F6QYZ4
names: Subcellular Location Annotation
messages: Membrane

35755:UL82 RS04670
gene id: 35755:UL82_RS04670
uniprot id: A0A0F6TCT9
names: Similarity
messages: Belongs to the UPF0434 family.

35755:UL82 RS03870
gene id: 35755:UL82_RS03870
uniprot id: A0A0F6TCS4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Heterodimer of an alpha and a beta subunit.
messages: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

35755:UL82 RS04690
gene id: 35755:UL82_RS04690
uniprot id: A0A0F6R079
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CbiN family.
messages: Cell membrane
messages: Forms an energy-coupling factor (ECF) transporter complex composed of an ATP-binding protein (A component, CbiO), a transmembrane protein (T component, CbiQ) and 2 possible substrate-capture proteins (S components, CbiM and CbiN) of unknown stoichimetry.
messages: Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import.

35755:UL82 RS05375
gene id: 35755:UL82_RS05375
uniprot id: A0A0F6QZP0
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

35755:UL82 RS01310
gene id: 35755:UL82_RS01310
uniprot id: A0A0F6TCN9
names: Caution
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
messages: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
messages: Could possibly oxidize fatty acids using specific components.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

35755:UL82 RS07060
gene id: 35755:UL82_RS07060
uniprot id: A0A0F6TDH3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

35755:UL82 RS02545
gene id: 35755:UL82_RS02545
uniprot id: A0A0F6QZI7
names: Similarity
messages: Belongs to the Nth/MutY family.

35755:UL82 RS03195
gene id: 35755:UL82_RS03195
uniprot id: A0A0F6QZS6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glutaminase PdxT/SNO family.
messages: Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
messages: In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer.

35755:UL82 RS00700
gene id: 35755:UL82_RS00700
uniprot id: A0A0F6TC21
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

35755:UL82 RS06385
gene id: 35755:UL82_RS06385
uniprot id: A0A0F6TDQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

35755:UL82 RS08140
gene id: 35755:UL82_RS08140
uniprot id: A0A0F6R0L8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Belongs to the precorrin methyltransferase family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

35755:UL82 RS05685
gene id: 35755:UL82_RS05685
uniprot id: A0A0F6TDM6
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

35755:UL82 RS01615
gene id: 35755:UL82_RS01615
uniprot id: A0A0F6R0P2
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

35755:UL82 RS09885
gene id: 35755:UL82_RS09885
uniprot id: A0A0F6R175
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

35755:UL82 RS00110
gene id: 35755:UL82_RS00110
uniprot id: A0A0F6QXY3
names: Subcellular Location Annotation
messages: Membrane

35755:UL82 RS02115
gene id: 35755:UL82_RS02115
uniprot id: A0A0F6TCY3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

35755:UL82 RS07720
gene id: 35755:UL82_RS07720
uniprot id: A0A0F6R0H4
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

35755:UL82 RS04945
gene id: 35755:UL82_RS04945
uniprot id: A0A0F6R1R2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase-binding protein RbpA family.
messages: Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters.
messages: Forms a complex with the RNAP catalytic core and with free principal sigma factors.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

35755:UL82 RS06195
gene id: 35755:UL82_RS06195
uniprot id: A0A0F6R267
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

35755:UL82 RS05430
gene id: 35755:UL82_RS05430
uniprot id: A0A0F6R1X1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

35755:UL82 RS01475
gene id: 35755:UL82_RS01475
uniprot id: A0A0F6R0M8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

35755:UL82 RS08035
gene id: 35755:UL82_RS08035
uniprot id: A0A0F6R2R4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

35755:UL82 RS09255
gene id: 35755:UL82_RS09255
uniprot id: A0A0F6R349
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

35755:UL82 RS04570
gene id: 35755:UL82_RS04570
uniprot id: A0A0F6QZF3
names: Similarity
messages: Belongs to the universal stress protein A family.

35755:UL82 RS10415
gene id: 35755:UL82_RS10415
uniprot id: A0A0F6R1D9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

35755:UL82 RS08445
gene id: 35755:UL82_RS08445
uniprot id: A0A0F6R1J1
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.

35755:UL82 RS07285
gene id: 35755:UL82_RS07285
uniprot id: A0A0F6R2H1
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

35755:UL82 RS03475
gene id: 35755:UL82_RS03475
uniprot id: A0A0F6TD72
names: Subcellular Location Annotation
messages: Membrane

35755:UL82 RS00225
gene id: 35755:UL82_RS00225
uniprot id: A0A0F6QYQ4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

35755:UL82 RS07210
gene id: 35755:UL82_RS07210
uniprot id: A0A0F6R2G4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

35755:UL82 RS07070
gene id: 35755:UL82_RS07070
uniprot id: A0A0F6R2F0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

35755:UL82 RS02390
gene id: 35755:UL82_RS02390
uniprot id: A0A0F6TCI0
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

35755:UL82 RS07020
gene id: 35755:UL82_RS07020
uniprot id: A0A0F6TE77
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

35755:UL82 RS02875
gene id: 35755:UL82_RS02875
uniprot id: A0A0F6QZM5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

35755:UL82 RS09030
gene id: 35755:UL82_RS09030
uniprot id: A0A0F6R320
names: Subcellular Location Annotation
messages: Membrane

35755:UL82 RS01260
gene id: 35755:UL82_RS01260
uniprot id: A0A0F6QZ32
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

35755:UL82 RS05090
gene id: 35755:UL82_RS05090
uniprot id: A0A0F6QZK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DcuA/DcuB transporter (TC 2.A.13.1) family.
messages: Cell inner membrane
messages: Membrane

35755:UL82 RS01630
gene id: 35755:UL82_RS01630
uniprot id: A0A0F6TC89
names: Subcellular Location Annotation
messages: Membrane

35755:UL82 RS09285
gene id: 35755:UL82_RS09285
uniprot id: A0A0F6TE19
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

35755:UL82 RS04645
gene id: 35755:UL82_RS04645
uniprot id: A0A0F6QZG1
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

35755:UL82 RS02630
gene id: 35755:UL82_RS02630
uniprot id: A0A0F6QYT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThrE exporter (TC 2.A.79) family.
messages: Membrane

35755:UL82 RS04995
gene id: 35755:UL82_RS04995
uniprot id: A0A0F6R1R8
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

35755:UL82 RS08215
gene id: 35755:UL82_RS08215
uniprot id: A0A0F6R0M9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

35755:UL82 RS04890
gene id: 35755:UL82_RS04890
uniprot id: A0A0F6TCZ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

35755:UL82 RS03510
gene id: 35755:UL82_RS03510
uniprot id: A0A0F6TD43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

35755:UL82 RS02700
gene id: 35755:UL82_RS02700
uniprot id: A0A0F6QZK4
names: Similarity
messages: Belongs to the GARS family.

35755:UL82 RS06760
gene id: 35755:UL82_RS06760
uniprot id: A0A0F6TE56
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

35755:UL82 RS00960
gene id: 35755:UL82_RS00960
uniprot id: A0A0F6QY94
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

35755:UL82 RS10380
gene id: 35755:UL82_RS10380
uniprot id: A0A0F6R246
names: Similarity
messages: Belongs to the UPF0371 family.

35755:UL82 RS09760
gene id: 35755:UL82_RS09760
uniprot id: A0A0F6TEV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

35755:UL82 RS09650
gene id: 35755:UL82_RS09650
uniprot id: A0A0F6R387
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.
messages: Cytoplasm
messages: Monomer.

35755:UL82 RS00905
gene id: 35755:UL82_RS00905
uniprot id: A0A0F6TCI8
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

35755:UL82 RS02205
gene id: 35755:UL82_RS02205
uniprot id: A0A0F6QYN4
names: Similarity
messages: Belongs to the AccD/PCCB family.

35755:UL82 RS08250
gene id: 35755:UL82_RS08250
uniprot id: A0A0F6TDU5
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
messages: Part of the 50S ribosomal subunit.

35755:UL82 RS01700
gene id: 35755:UL82_RS01700
uniprot id: A0A0F6QZ88
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

35755:UL82 RS00880
gene id: 35755:UL82_RS00880
uniprot id: A0A0F6TBZ9
names: Similarity
messages: Belongs to the Nudix hydrolase family. PCD1 subfamily.

35755:UL82 RS05870
gene id: 35755:UL82_RS05870
uniprot id: A0A0F6R235
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

35755:UL82 RS02135
gene id: 35755:UL82_RS02135
uniprot id: A0A0F6R0V3
names: Similarity
messages: Belongs to the peptidase C40 family.

35755:UL82 RS01555
gene id: 35755:UL82_RS01555
uniprot id: A0A0F6QZ69
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

35755:UL82 RS03455
gene id: 35755:UL82_RS03455
uniprot id: A0A0F6QZU4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein L14 (rplN).

35755:UL82 RS02865
gene id: 35755:UL82_RS02865
uniprot id: A0A0F6R144
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Catalyzes the sodium-dependent uptake of extracellular L-proline.
messages: Cell membrane
messages: Membrane

35755:UL82 RS01525
gene id: 35755:UL82_RS01525
uniprot id: A0A0F6TCB8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

35755:UL82 RS02705
gene id: 35755:UL82_RS02705
uniprot id: A0A0F6TCK4
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

35755:UL82 RS03415
gene id: 35755:UL82_RS03415
uniprot id: A0A0F6R1B2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

35755:UL82 RS01210
gene id: 35755:UL82_RS01210
uniprot id: A0A0F6QZ26
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

35755:UL82 RS07870
gene id: 35755:UL82_RS07870
uniprot id: A0A0F6R2P2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic pantothenate kinase family.
messages: Cytoplasm

35755:UL82 RS04270
gene id: 35755:UL82_RS04270
uniprot id: A0A0F6TCV1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

35755:UL82 RS08430
gene id: 35755:UL82_RS08430
uniprot id: A0A0F6R0S6
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.

35755:UL82 RS08195
gene id: 35755:UL82_RS08195
uniprot id: A0A0F6R2T2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

35755:UL82 RS06410
gene id: 35755:UL82_RS06410
uniprot id: A0A0F6TDS1
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

35755:UL82 RS02795
gene id: 35755:UL82_RS02795
uniprot id: A0A0F6TDE0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetyltransferase family. MshD subfamily.
messages: Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

35755:UL82 RS03535
gene id: 35755:UL82_RS03535
uniprot id: A0A0F6TD77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

35755:UL82 RS02945
gene id: 35755:UL82_RS02945
uniprot id: A0A0F6QZN2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

35755:UL82 RS05025
gene id: 35755:UL82_RS05025
uniprot id: A0A0F6TDF7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

35755:UL82 RS06025
gene id: 35755:UL82_RS06025
uniprot id: A0A0F6TE02
names: Subcellular Location Annotation
messages: Membrane

35755:UL82 RS10190
gene id: 35755:UL82_RS10190
uniprot id: A0A0F6R222
names: Similarity
messages: Belongs to the four-carbon acid sugar kinase family.

35755:UL82 RS07255
gene id: 35755:UL82_RS07255
uniprot id: A0A0F6R0C2
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

35755:UL82 RS03925
gene id: 35755:UL82_RS03925
uniprot id: A0A0F6QZZ8
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

35755:UL82 RS07065
gene id: 35755:UL82_RS07065
uniprot id: A0A0F6R0A0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

35755:UL82 RS00130
gene id: 35755:UL82_RS00130
uniprot id: A0A0F6TCC1
names: Subcellular Location Annotation
messages: Membrane

35755:UL82 RS06955
gene id: 35755:UL82_RS06955
uniprot id: A0A0F6R089
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

35755:UL82 RS08185
gene id: 35755:UL82_RS08185
uniprot id: A0A0F6TDT9
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

35755:UL82 RS01845
gene id: 35755:UL82_RS01845
uniprot id: A0A0F6R0R5
names: Similarity
messages: Belongs to the EccD/Snm4 family.

35755:UL82 RS05070
gene id: 35755:UL82_RS05070
uniprot id: A0A0F6R1S7
names: Similarity
messages: Belongs to the peptidase M18 family.

35755:UL82 RS05110
gene id: 35755:UL82_RS05110
uniprot id: A0A0F6TDI8
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

35755:UL82 RS00260
gene id: 35755:UL82_RS00260
uniprot id: A0A0F6QXZ8
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

35755:UL82 RS10420
gene id: 35755:UL82_RS10420
uniprot id: A0A0F6R3E9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

35755:UL82 RS02460
gene id: 35755:UL82_RS02460
uniprot id: A0A0F6R0Z3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

35755:UL82 RS07585
gene id: 35755:UL82_RS07585
uniprot id: A0A0F6R174
names: Similarity
messages: Belongs to the LOG family.

35755:UL82 RS06665
gene id: 35755:UL82_RS06665
uniprot id: A0A0F6R054
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

35755:UL82 RS07785
gene id: 35755:UL82_RS07785
uniprot id: A0A0F6TDM8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

35755:UL82 RS03920
gene id: 35755:UL82_RS03920
uniprot id: A0A0F6TCP5
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

35755:UL82 RS01875
gene id: 35755:UL82_RS01875
uniprot id: A0A0F6TCW4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

35755:UL82 RS01250
gene id: 35755:UL82_RS01250
uniprot id: A0A0F6R0K7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

35755:UL82 RS02495
gene id: 35755:UL82_RS02495
uniprot id: A0A0F6QZI3
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

35755:UL82 RS04640
gene id: 35755:UL82_RS04640
uniprot id: A0A0F6TDP8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

35755:UL82 RS04310
gene id: 35755:UL82_RS04310
uniprot id: A0A0F6QZC9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

35755:UL82 RS03865
gene id: 35755:UL82_RS03865
uniprot id: A0A0F6R1F7
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta subunit.
messages: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

35755:UL82 RS07000
gene id: 35755:UL82_RS07000
uniprot id: A0A0F6R107
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Membrane
messages: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).

35755:UL82 RS03675
gene id: 35755:UL82_RS03675
uniprot id: A0A0F6TCM8
names: Subcellular Location Annotation
messages: Membrane

35755:UL82 RS06530
gene id: 35755:UL82_RS06530
uniprot id: A0A0F6R0U5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

35755:UL82 RS07865
gene id: 35755:UL82_RS07865
uniprot id: A0A0F6R0J3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

35755:UL82 RS02110
gene id: 35755:UL82_RS02110
uniprot id: A0A0F6QYM3
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

35755:UL82 RS00080
gene id: 35755:UL82_RS00080
uniprot id: A0A0F6TCB5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

35755:UL82 RS09795
gene id: 35755:UL82_RS09795
uniprot id: A0A0F6R3A1
names: Activity Regulation
names: Caution
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

35755:UL82 RS07605
gene id: 35755:UL82_RS07605
uniprot id: A0A0F6TDL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family.
messages: Membrane

35755:UL82 RS01680
gene id: 35755:UL82_RS01680
uniprot id: A0A0F6TCU5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

35755:UL82 RS02310
gene id: 35755:UL82_RS02310
uniprot id: A0A0F6R0X4
names: Subcellular Location Annotation
messages: Membrane

35755:UL82 RS07050
gene id: 35755:UL82_RS07050
uniprot id: A0A0F6R112
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

35755:UL82 RS07555
gene id: 35755:UL82_RS07555
uniprot id: A0A0F6R2K0
names: Similarity
messages: Belongs to the alpha-acetolactate decarboxylase family.

35755:UL82 RS04650
gene id: 35755:UL82_RS04650
uniprot id: A0A0F6R1M7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

35755:UL82 RS01750
gene id: 35755:UL82_RS01750
uniprot id: A0A0F6QZ95
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

35755:UL82 RS01255
gene id: 35755:UL82_RS01255
uniprot id: A0A0F6TCN5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protoporphyrinogen/coproporphyrinogen oxidase family. Coproporphyrinogen III oxidase subfamily.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the oxidation of coproporphyrinogen III to coproporphyrin III.

35755:UL82 RS08650
gene id: 35755:UL82_RS08650
uniprot id: A0A0F6R1K6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division.

35755:UL82 RS10500
gene id: 35755:UL82_RS10500
uniprot id: A0A0F6TEL8
names: Similarity
messages: Belongs to the thioredoxin family.

35755:UL82 RS02985
gene id: 35755:UL82_RS02985
uniprot id: A0A0F6R156
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

35755:UL82 RS03435
gene id: 35755:UL82_RS03435
uniprot id: A0A0F6QZ34
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

35755:UL82 RS07805
gene id: 35755:UL82_RS07805
uniprot id: A0A0F6R1A1
names: Similarity
messages: Belongs to the FBPase class 2 family.