351160:RCI RS02945
gene id: 351160:RCI_RS02945
uniprot id: Q0W1Q5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 2 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

351160:RCI RS12695
gene id: 351160:RCI_RS12695
uniprot id: Q0W7J8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

351160:RCI RS14715
gene id: 351160:RCI_RS14715
uniprot id: Q0W8P1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal Rpo11/eukaryotic RPB11/RPC19 RNA polymerase subunit family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

351160:RCI RS09770
gene id: 351160:RCI_RS09770
uniprot id: Q0W5U6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the archaeal DNA polymerase II family.
messages: Heterodimer of a large subunit and a small subunit.
messages: Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase (By similarity).

351160:RCI RS05340
gene id: 351160:RCI_RS05340
uniprot id: Q0W345
names: Similarity
messages: Belongs to the class-I fumarase family.

351160:RCI RS09235
gene id: 351160:RCI_RS09235
uniprot id: Q0W5I3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PyrI family.
messages: Binds 1 zinc ion per subunit.
messages: Contains catalytic and regulatory chains.
messages: Involved in allosteric regulation of aspartate carbamoyltransferase.

351160:RCI RS02175
gene id: 351160:RCI_RS02175
uniprot id: Q0W196
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PdxS/SNZ family.
messages: Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
messages: In the presence of PdxT, forms a dodecamer of heterodimers.

351160:RCI RS01300
gene id: 351160:RCI_RS01300
uniprot id: Q0W0S6
names: Subcellular Location Annotation
messages: Cytoplasm

351160:RCI RS12710
gene id: 351160:RCI_RS12710
uniprot id: Q0W7K1
names: Similarity
messages: Belongs to the thiolase-like superfamily. UPF0219 family.

351160:RCI RS01340
gene id: 351160:RCI_RS01340
uniprot id: Q0W0T4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. O-phosphoseryl-tRNA(Cys) synthetase subfamily.
messages: Catalyzes the attachment of O-phosphoserine (Sep) to tRNA(Cys).
messages: Homotetramer. Interacts with SepCysS.

351160:RCI RS10065
gene id: 351160:RCI_RS10065
uniprot id: Q0W606
names: Subcellular Location Annotation
messages: Membrane

351160:RCI RS02810
gene id: 351160:RCI_RS02810
uniprot id: Q0W1M3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA-PH family.
messages: Cytoplasm

351160:RCI RS13160
gene id: 351160:RCI_RS13160
uniprot id: Q0W7U3
names: Cofactor
messages: Binds 1 zinc ion per subunit.

351160:RCI RS06205
gene id: 351160:RCI_RS06205
uniprot id: Q0W3M6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC-2 integral membrane protein family. Lipooligosaccharide exporter (TC 3.A.1.102) subfamily.
messages: Membrane
messages: Part of the ABC transporter complex NodIJ involved in the export of the nodulation factors (Nod factors), the bacterial signal molecules that induce symbiosis and subsequent nodulation induction. Nod factors are LCO (lipo-chitin oligosaccharide), a modified beta-1,4-linked N-acetylglucosamine oligosaccharide. This subunit encodes the transporter.
messages: The complex is composed of two ATP-binding proteins (NodI) and two transmembrane proteins (NodJ).

351160:RCI RS03785
gene id: 351160:RCI_RS03785
uniprot id: Q0W276
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

351160:RCI RS11015
gene id: 351160:RCI_RS11015
uniprot id: Q0W6K3
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Feedback inhibited by histidine.

351160:RCI RS14970
gene id: 351160:RCI_RS14970
uniprot id: Q0W8U1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FTR family.
messages: Catalyzes the reversible transfer of a formyl group from formylmethanofuran (formyl-MFR) to tetrahydromethanopterin (H(4)MPT) to produce 5-formyl tetrahydromethanopterin (5-formyl-H(4)MPT) and methanofuran (MFR).
messages: Cytoplasm
messages: Homotetramer.

351160:RCI RS04065
gene id: 351160:RCI_RS04065
uniprot id: Q0W2D8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

351160:RCI RS11020
gene id: 351160:RCI_RS11020
uniprot id: Q0W6K4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GGGP/HepGP synthase family. Group I subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids.

351160:RCI RS10475
gene id: 351160:RCI_RS10475
uniprot id: Q0W688
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase Z family.
messages: Binds 2 Zn(2+) ions.
messages: Homodimer.
messages: Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.

351160:RCI RS11055
gene id: 351160:RCI_RS11055
uniprot id: Q0W6L1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. Hel308 subfamily.
messages: DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks.
messages: Monomer.

351160:RCI RS05070
gene id: 351160:RCI_RS05070
uniprot id: Q0W2Z0
names: Similarity
messages: Belongs to the SDO1/SBDS family.

351160:RCI RS04260
gene id: 351160:RCI_RS04260
uniprot id: Q0W2H9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

351160:RCI RS12460
gene id: 351160:RCI_RS12460
uniprot id: Q0W7F2
names: Subcellular Location Annotation
messages: Membrane

351160:RCI RS10730
gene id: 351160:RCI_RS10730
uniprot id: Q0W6E3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamine synthetase family.
messages: Cytoplasm

351160:RCI RS10665
gene id: 351160:RCI_RS10665
uniprot id: Q0W6D0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

351160:RCI RS04305
gene id: 351160:RCI_RS04305
uniprot id: Q0W2I8
names: Subcellular Location Annotation
messages: Membrane

351160:RCI RS04660
gene id: 351160:RCI_RS04660
uniprot id: Q0W2Q8
names: Subcellular Location Annotation
messages: Membrane

351160:RCI RS03960
gene id: 351160:RCI_RS03960
uniprot id: Q0W2B5
names: Subcellular Location Annotation
messages: Membrane

351160:RCI RS11365
gene id: 351160:RCI_RS11365
uniprot id: Q0W6S7
names: Subunit
messages: Heterotetramer of one alpha, one beta, one delta and one gamma chain.

351160:RCI RS00165
gene id: 351160:RCI_RS00165
uniprot id: Q0W058
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

351160:RCI RS04080
gene id: 351160:RCI_RS04080
uniprot id: Q0W2E1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

351160:RCI RS09975
gene id: 351160:RCI_RS09975
uniprot id: Q0W5Y9
names: Similarity
messages: Belongs to the UPF0215 family.

351160:RCI RS03220
gene id: 351160:RCI_RS03220
uniprot id: Q0W1V9
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

351160:RCI RS03250
gene id: 351160:RCI_RS03250
uniprot id: Q0W1W4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Monomer.

351160:RCI RS13155
gene id: 351160:RCI_RS13155
uniprot id: Q0W7U2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

351160:RCI RS01330
gene id: 351160:RCI_RS01330
uniprot id: Q0W0T2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

351160:RCI RS02655
gene id: 351160:RCI_RS02655
uniprot id: Q0W1J0
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruD family.
messages: Could be responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.

351160:RCI RS00370
gene id: 351160:RCI_RS00370
uniprot id: Q0W095
names: Similarity
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.

351160:RCI RS12120
gene id: 351160:RCI_RS12120
uniprot id: Q0W782
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

351160:RCI RS07885
gene id: 351160:RCI_RS07885
uniprot id: Q0W4N8
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

351160:RCI RS01655
gene id: 351160:RCI_RS01655
uniprot id: Q0W0Z7
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

351160:RCI RS02265
gene id: 351160:RCI_RS02265
uniprot id: Q0W1B4
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Catalyzes the hydrolysis of S-inosyl-L-homocysteine (SIH) to L-homocysteine (Hcy) and inosine. Likely functions in a S-adenosyl-L-methionine (SAM) recycling pathway from S-adenosyl-L-homocysteine (SAH) produced from SAM-dependent methylation reactions. Can also catalyze the reverse reaction in vitro, i.e. the synthesis of SIH from Hcy and inosine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: SAH is a product of SAM methyltransferases and is known to be a feedback inhibitor of these enzymes. As a result of this inhibition, organisms have evolved efficient enzymes to metabolize SAH via different pathways. The pathway found in methanogens differs from the canonical pathway, it uses the deamination of S-adenosyl-L-homocysteine to form S-inosyl-L-homocysteine for the regeneration of SAM from S-adenosyl-L-homocysteine.

351160:RCI RS07195
gene id: 351160:RCI_RS07195
uniprot id: Q0W485
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

351160:RCI RS06835
gene id: 351160:RCI_RS06835
uniprot id: Q0W408
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Does not function as a glutathione-disulfide oxidoreductase in the presence of glutathione and glutathione reductase. Has low thioredoxin activity in vitro.

351160:RCI RS12220
gene id: 351160:RCI_RS12220
uniprot id: Q0W7A0
names: Similarity
messages: Belongs to the FPG family.

351160:RCI RS14385
gene id: 351160:RCI_RS14385
uniprot id: Q0W8H7
names: Similarity
messages: Belongs to the DEAD box helicase family.

351160:RCI RS01940
gene id: 351160:RCI_RS01940
uniprot id: Q0W150
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

351160:RCI RS04085
gene id: 351160:RCI_RS04085
uniprot id: Q0W2E2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

351160:RCI RS06380
gene id: 351160:RCI_RS06380
uniprot id: Q0W3R1
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

351160:RCI RS00290
gene id: 351160:RCI_RS00290
uniprot id: Q0W081
names: Similarity
messages: Belongs to the UPF0212 family.

351160:RCI RS08310
gene id: 351160:RCI_RS08310
uniprot id: Q0W4X6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm

351160:RCI RS03340
gene id: 351160:RCI_RS03340
uniprot id: Q0W1Y2
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

351160:RCI RS03360
gene id: 351160:RCI_RS03360
uniprot id: Q0W1Y6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

351160:RCI RS05405
gene id: 351160:RCI_RS05405
uniprot id: Q0W358
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

351160:RCI RS01105
gene id: 351160:RCI_RS01105
uniprot id: Q0W0N9
names: Function
names: Similarity
messages: Belongs to the adenylate cyclase family. DacZ subfamily.
messages: Diadenylate cyclase that catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP is a second messenger for intracellular signal transduction involved in the control of important regulatory processes such as osmoregulation.

351160:RCI RS11090
gene id: 351160:RCI_RS11090
uniprot id: Q0W6L8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic release factor 1 family.
messages: Cytoplasm
messages: Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA.
messages: Heterodimer of two subunits, one of which binds GTP.

351160:RCI RS14325
gene id: 351160:RCI_RS14325
uniprot id: Q0W8G7
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL30 family.

351160:RCI RS02215
gene id: 351160:RCI_RS02215
uniprot id: Q0W1A4
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

351160:RCI RS09560
gene id: 351160:RCI_RS09560
uniprot id: Q0W5Q2
names: Similarity
messages: Belongs to the peptidase C56 family.

351160:RCI RS09055
gene id: 351160:RCI_RS09055
uniprot id: Q0W5E8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TOP6B family.
messages: Homodimer. Heterotetramer of two Top6A and two Top6B chains.
messages: Relaxes both positive and negative superturns and exhibits a strong decatenase activity.

351160:RCI RS00025
gene id: 351160:RCI_RS00025
uniprot id: Q0W029
names: Similarity
messages: Belongs to the helicase family. RAD25/XPB subfamily.

351160:RCI RS04100
gene id: 351160:RCI_RS04100
uniprot id: Q0W2E5
names: Similarity
messages: Belongs to the eukaryotic/archaeal PrmC-related family.

351160:RCI RS06910
gene id: 351160:RCI_RS06910
uniprot id: Q0W423
names: Subcellular Location Annotation
messages: Membrane

351160:RCI RS09350
gene id: 351160:RCI_RS09350
uniprot id: Q0W5K7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Membrane

351160:RCI RS01385
gene id: 351160:RCI_RS01385
uniprot id: Q0W0U3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FwdB family.
messages: Catalyzes the reversible oxidation of CO(2) and methanofuran (MFR) to N-formylmethanofuran (CHO-MFR). This enzyme is oxygen-labile.
messages: This enzyme is composed of six subunits FwdA, FwdC, FwdD, FwdE, FwdF and FwdG.

351160:RCI RS03060
gene id: 351160:RCI_RS03060
uniprot id: Q0W1S7
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family. N(4) subfamily.

351160:RCI RS02785
gene id: 351160:RCI_RS02785
uniprot id: Q0W1L8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).

351160:RCI RS13130
gene id: 351160:RCI_RS13130
uniprot id: Q0W7T6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

351160:RCI RS15390
gene id: 351160:RCI_RS15390
uniprot id: Q0W905
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.

351160:RCI RS13870
gene id: 351160:RCI_RS13870
uniprot id: Q0W881
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CdhC family.
messages: Binds 1 [Ni-Fe-S] cluster.
messages: Monomer. The ACDS complex is made up of alpha, epsilon, beta, gamma and delta chains with a probable stoichiometry of (alpha(2)epsilon(2))(4)-beta(8)-(gamma(1)delta(1))(8).
messages: Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing autotrophic growth from CO(2). The alpha-epsilon complex generates CO from CO(2), while the beta subunit (this protein) combines the CO with CoA and a methyl group to form acetyl-CoA. The methyl group, which is incorporated into acetyl-CoA, is transferred to the beta subunit by a corrinoid iron-sulfur protein (the gamma-delta complex).

351160:RCI RS08145
gene id: 351160:RCI_RS08145
uniprot id: Q0W4U3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).

351160:RCI RS14130
gene id: 351160:RCI_RS14130
uniprot id: Q0W8C9
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

351160:RCI RS03875
gene id: 351160:RCI_RS03875
uniprot id: Q0W296
names: Similarity
messages: Belongs to the phosphohexose mutase family.

351160:RCI RS11270
gene id: 351160:RCI_RS11270
uniprot id: Q0W6Q6
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

351160:RCI RS04815
gene id: 351160:RCI_RS04815
uniprot id: Q0W2U1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

351160:RCI RS10430
gene id: 351160:RCI_RS10430
uniprot id: Q0W678
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThiI family.
messages: Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

351160:RCI RS07750
gene id: 351160:RCI_RS07750
uniprot id: Q0W4L3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

351160:RCI RS13065
gene id: 351160:RCI_RS13065
uniprot id: Q0W7S3
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

351160:RCI RS08200
gene id: 351160:RCI_RS08200
uniprot id: Q0W4V4
names: Subcellular Location Annotation
messages: Membrane

351160:RCI RS06010
gene id: 351160:RCI_RS06010
uniprot id: Q0W3I5
names: Subcellular Location Annotation
messages: Membrane

351160:RCI RS03285
gene id: 351160:RCI_RS03285
uniprot id: Q0W1X1
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL32 family.

351160:RCI RS04175
gene id: 351160:RCI_RS04175
uniprot id: Q0W2G1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. Archaeal SRP consists of a 7S RNA molecule of 300 nucleotides and two protein subunits: SRP54 and SRP19.

351160:RCI RS03255
gene id: 351160:RCI_RS03255
uniprot id: Q0W1W5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of alpha (SecY), beta (SecG) and gamma (SecE) subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. May interact with SecDF, and other proteins may be involved.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

351160:RCI RS10625
gene id: 351160:RCI_RS10625
uniprot id: Q0W6C2
names: Similarity
messages: Belongs to the HisA/HisF family.

351160:RCI RS14160
gene id: 351160:RCI_RS14160
uniprot id: Q0W8D5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease activity. May be involved in RNA degradation.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Archaeal RNase J subfamily.
messages: Binds 2 Zn(2+) ions per subunit. It is not clear if Zn(2+) or Mg(2+) is physiologically important.
messages: Cytoplasm
messages: Homodimer.

351160:RCI RS03375
gene id: 351160:RCI_RS03375
uniprot id: Q0W1Y9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L24e.

351160:RCI RS00465
gene id: 351160:RCI_RS00465
uniprot id: Q0W0B3
names: Similarity
messages: Belongs to the SAM hydrolase / SAM-dependent halogenase family.

351160:RCI RS03280
gene id: 351160:RCI_RS03280
uniprot id: Q0W1X0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL19 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

351160:RCI RS04345
gene id: 351160:RCI_RS04345
uniprot id: Q0W2J4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PCNA family.
messages: Homotrimer. The subunits circularize to form a toroid; DNA passes through its center. Replication factor C (RFC) is required to load the toroid on the DNA.
messages: Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication.

351160:RCI RS12155
gene id: 351160:RCI_RS12155
uniprot id: Q0W790
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

351160:RCI RS11025
gene id: 351160:RCI_RS11025
uniprot id: Q0W6K5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GGGP/HepGP synthase family. Group I subfamily.
messages: Cytoplasm
messages: Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids.

351160:RCI RS02135
gene id: 351160:RCI_RS02135
uniprot id: Q0W189
names: Similarity
messages: Belongs to the DeoC/FbaB aldolase family.

351160:RCI RS11975
gene id: 351160:RCI_RS11975
uniprot id: Q0W752
names: Similarity
messages: Belongs to the archaeal-type GPI family.

351160:RCI RS15205
gene id: 351160:RCI_RS15205
uniprot id: Q0W8W9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL8 family.
messages: Cytoplasm
messages: Multifunctional RNA-binding protein that recognizes the K-turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs.
messages: Part of the 50S ribosomal subunit. Probably part of the RNase P complex.

351160:RCI RS09605
gene id: 351160:RCI_RS09605
uniprot id: Q0W5R2
names: Subcellular Location Annotation
messages: Membrane

351160:RCI RS13980
gene id: 351160:RCI_RS13980
uniprot id: Q0W8A1
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

351160:RCI RS05425
gene id: 351160:RCI_RS05425
uniprot id: Q0W362
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit.

351160:RCI RS02530
gene id: 351160:RCI_RS02530
uniprot id: Q0W1G3
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.

351160:RCI RS08100
gene id: 351160:RCI_RS08100
uniprot id: Q0W4T3
names: Cofactor
names: Similarity
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.
messages: Binds 1 zinc ion per subunit.

351160:RCI RS09195
gene id: 351160:RCI_RS09195
uniprot id: Q0W5H5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

351160:RCI RS08485
gene id: 351160:RCI_RS08485
uniprot id: Q0W514
names: Function
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.

351160:RCI RS12240
gene id: 351160:RCI_RS12240
uniprot id: Q0W7A4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

351160:RCI RS00875
gene id: 351160:RCI_RS00875
uniprot id: Q0W0J5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

351160:RCI RS14615
gene id: 351160:RCI_RS14615
uniprot id: Q0W8M3
names: Cofactor
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS27 family.
messages: Binds 1 zinc ion per subunit.

351160:RCI RS03650
gene id: 351160:RCI_RS03650
uniprot id: Q0W248
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

351160:RCI RS03300
gene id: 351160:RCI_RS03300
uniprot id: Q0W1X4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles.
messages: Part of the 30S ribosomal subunit.

351160:RCI RS11350
gene id: 351160:RCI_RS11350
uniprot id: Q0W6S4
names: Function
names: Similarity
messages: Belongs to the archaeal IMP cyclohydrolase family.
messages: Catalyzes the cyclization of 5-formylamidoimidazole-4-carboxamide ribonucleotide to IMP.

351160:RCI RS13395
gene id: 351160:RCI_RS13395
uniprot id: Q0W7Y9
names: Similarity
messages: Belongs to the DtxR/MntR family.

351160:RCI RS15220
gene id: 351160:RCI_RS15220
uniprot id: Q0W8X1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

351160:RCI RS15015
gene id: 351160:RCI_RS15015
uniprot id: Q0W8U9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCH family.
messages: Catalyzes the reversible interconversion of 5-formyl-H(4)MPT to methenyl-H(4)MPT(+).
messages: Cytoplasm

351160:RCI RS00540
gene id: 351160:RCI_RS00540
uniprot id: Q0W0C9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.
messages: Cytoplasm
messages: Homodimer.

351160:RCI RS14030
gene id: 351160:RCI_RS14030
uniprot id: Q0W8B1
names: Subcellular Location Annotation
messages: Membrane

351160:RCI RS14645
gene id: 351160:RCI_RS14645
uniprot id: Q0W8N0
names: Similarity
messages: Belongs to the pyruvate kinase family.
messages: In the C-terminal section; belongs to the PEP-utilizing enzyme family.

351160:RCI RS09470
gene id: 351160:RCI_RS09470
uniprot id: Q0W5N4
names: Similarity
messages: Belongs to the HsdR family.

351160:RCI RS08080
gene id: 351160:RCI_RS08080
uniprot id: Q0W4S8
names: Similarity
messages: Belongs to the ribose-phosphate pyrophosphokinase family.

351160:RCI RS00045
gene id: 351160:RCI_RS00045
uniprot id: Q0W033
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

351160:RCI RS13055
gene id: 351160:RCI_RS13055
uniprot id: Q0W7S1
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.

351160:RCI RS09795
gene id: 351160:RCI_RS09795
uniprot id: Q0W5V1
names: Subcellular Location Annotation
messages: Membrane

351160:RCI RS04590
gene id: 351160:RCI_RS04590
uniprot id: Q0W2P3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Monomer. Component of the KEOPS complex that consists of Kae1, Bud32, Cgi121 and Pcc1; the whole complex dimerizes.
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Kae1 likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity.

351160:RCI RS11235
gene id: 351160:RCI_RS11235
uniprot id: Q0W6P9
names: Function
names: Similarity
messages: Belongs to the HypA/HybF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.

351160:RCI RS02790
gene id: 351160:RCI_RS02790
uniprot id: Q0W1L9
names: Function
names: Similarity
messages: Belongs to the Thz kinase family.
messages: Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).

351160:RCI RS10165
gene id: 351160:RCI_RS10165
uniprot id: Q0W628
names: Similarity
messages: Belongs to the TrpF family.

351160:RCI RS01210
gene id: 351160:RCI_RS01210
uniprot id: Q0W0R0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

351160:RCI RS00110
gene id: 351160:RCI_RS00110
uniprot id: Q0W047
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY (alpha), SecG (beta) and SecE (gamma) subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. May interact with SecDF, and other proteins may be involved.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.
messages: Membrane

351160:RCI RS00735
gene id: 351160:RCI_RS00735
uniprot id: Q0W0G8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TYW1 family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Component of the wyosine derivatives biosynthesis pathway that catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine (imG-14) on guanosine-37 of tRNA(Phe).
messages: Cytoplasm
messages: Monomer.

351160:RCI RS01840
gene id: 351160:RCI_RS01840
uniprot id: Q0W130
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DeoC/FbaB aldolase family. ADHS subfamily.
messages: Catalyzes a transaldol reaction between 6-deoxy-5-ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids.
messages: Homodecamer.

351160:RCI RS00270
gene id: 351160:RCI_RS00270
uniprot id: Q0W077
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

351160:RCI RS07700
gene id: 351160:RCI_RS07700
uniprot id: Q0W4K2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SEC61-beta family.
messages: Cell membrane
messages: Component of the protein translocase complex. Heterotrimer consisting of alpha (SecY), beta (SecG) and gamma (SecE) subunits. Can form oligomers of the heterotrimer.
messages: Involved in protein export. The function of the beta subunit is unknown, but it may be involved in stabilization of the trimeric complex.

351160:RCI RS14550
gene id: 351160:RCI_RS14550
uniprot id: Q0W8K9
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

351160:RCI RS01575
gene id: 351160:RCI_RS01575
uniprot id: Q0W0Y4
names: Function
names: Similarity
messages: Belongs to the DPH1/DPH2 family.
messages: Catalyzes the first step of diphthamide biosynthesis, i.e. the transfer of the 3-amino-3-carboxypropyl group from S-adenosyl-L-methionine (SAM) to the C2 position of the imidazole ring of the target histidine residue in translation elongation factor 2 (EF-2).

351160:RCI RS06955
gene id: 351160:RCI_RS06955
uniprot id: Q0W432
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

351160:RCI RS09670
gene id: 351160:RCI_RS09670
uniprot id: Q0W5S6
names: Subunit
messages: Homotetramer.

351160:RCI RS04205
gene id: 351160:RCI_RS04205
uniprot id: Q0W2G7
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

351160:RCI RS07010
gene id: 351160:RCI_RS07010
uniprot id: Q0W443
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the NifH/BchL/ChlL family.
messages: Binds 1 [4Fe-4S] cluster per dimer.
messages: Homodimer.
messages: The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein.
messages: The reversible ADP-ribosylation of Arg-97 inactivates the nitrogenase reductase and regulates nitrogenase activity.

351160:RCI RS06990
gene id: 351160:RCI_RS06990
uniprot id: Q0W439
names: Similarity
messages: Belongs to the NifD/NifK/NifE/NifN family.

351160:RCI RS06530
gene id: 351160:RCI_RS06530
uniprot id: Q0W3U4
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

351160:RCI RS13475
gene id: 351160:RCI_RS13475
uniprot id: Q0W806
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.

351160:RCI RS09710
gene id: 351160:RCI_RS09710
uniprot id: Q0W5T4
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

351160:RCI RS13770
gene id: 351160:RCI_RS13770
uniprot id: Q0W861
names: Function
names: Similarity
messages: Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB. Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation. Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently.
messages: Belongs to the archease family.

351160:RCI RS05695
gene id: 351160:RCI_RS05695
uniprot id: Q0W3B7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

351160:RCI RS13810
gene id: 351160:RCI_RS13810
uniprot id: Q0W869
names: Subcellular Location Annotation
messages: Cell membrane

351160:RCI RS09240
gene id: 351160:RCI_RS09240
uniprot id: Q0W5I4
names: Similarity
messages: Belongs to the HMG-CoA reductase family.

351160:RCI RS14295
gene id: 351160:RCI_RS14295
uniprot id: Q0W8G1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

351160:RCI RS05445
gene id: 351160:RCI_RS05445
uniprot id: Q0W366
names: Function
names: Similarity
messages: Belongs to the V-ATPase E subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

351160:RCI RS04495
gene id: 351160:RCI_RS04495
uniprot id: Q0W2M4
names: Cofactor
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

351160:RCI RS02770
gene id: 351160:RCI_RS02770
uniprot id: Q0W1L4
names: Subcellular Location Annotation
messages: Membrane

351160:RCI RS04445
gene id: 351160:RCI_RS04445
uniprot id: Q0W2L4
names: Similarity
messages: Belongs to the arginase family.

351160:RCI RS10855
gene id: 351160:RCI_RS10855
uniprot id: Q0W6G9
names: Similarity
messages: Belongs to the catalase family.

351160:RCI RS14830
gene id: 351160:RCI_RS14830
uniprot id: Q0W8R4
names: Subcellular Location Annotation
messages: Membrane

351160:RCI RS05300
gene id: 351160:RCI_RS05300
uniprot id: Q0W337
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MtrD family.
messages: Cell membrane
messages: Part of a complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step.
messages: The complex is composed of 8 subunits; MtrA, MtrB, MtrC, MtrD, MtrE, MtrF, MtrG and MtrH.

351160:RCI RS03350
gene id: 351160:RCI_RS03350
uniprot id: Q0W1Y4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

351160:RCI RS03330
gene id: 351160:RCI_RS03330
uniprot id: Q0W1Y0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic/archaeal RNase P protein component 1 family.
messages: Consists of a catalytic RNA component and at least 4-5 protein subunits.
messages: Cytoplasm
messages: Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.

351160:RCI RS04210
gene id: 351160:RCI_RS04210
uniprot id: Q0W2G8
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family. N(4) subfamily.

351160:RCI RS04600
gene id: 351160:RCI_RS04600
uniprot id: Q0W2P5
names: Function
names: Similarity
messages: Belongs to the MTD family.
messages: Catalyzes the reversible reduction of methenyl-H(4)MPT(+) to methylene-H(4)MPT.

351160:RCI RS07245
gene id: 351160:RCI_RS07245
uniprot id: Q0W498
names: Function
names: Similarity
messages: Belongs to the group II decarboxylase family. MfnA subfamily.
messages: Catalyzes the decarboxylation of L-tyrosine to produce tyramine for methanofuran biosynthesis. Can also catalyze the decarboxylation of L-aspartate to produce beta-alanine for coenzyme A (CoA) biosynthesis.

351160:RCI RS00130
gene id: 351160:RCI_RS00130
uniprot id: Q0W051
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the 50S ribosomal subunit. Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Forms a heptameric L10(L12)2(L12)2(L12)2 complex, where L10 forms an elongated spine to which the L12 dimers bind in a sequential fashion.

351160:RCI RS06610
gene id: 351160:RCI_RS06610
uniprot id: Q0W3V9
names: Subcellular Location Annotation
messages: Membrane

351160:RCI RS10395
gene id: 351160:RCI_RS10395
uniprot id: Q0W672
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

351160:RCI RS00065
gene id: 351160:RCI_RS00065
uniprot id: Q0W037
names: Function
names: Similarity
names: Subunit
messages: Belongs to the activator 1 small subunits family. RfcS subfamily.
messages: Heteromultimer composed of small subunits (RfcS) and large subunits (RfcL).
messages: Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA.

351160:RCI RS00860
gene id: 351160:RCI_RS00860
uniprot id: Q0W0J2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

351160:RCI RS00790
gene id: 351160:RCI_RS00790
uniprot id: Q0W0H9
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the eIF-2B alpha/beta/delta subunits family. R15P isomerase subfamily.
messages: Catalyzes the isomerization of ribose 1,5-bisphosphate (R15P) to ribulose 1,5-bisphosphate (RuBP), the CO(2) acceptor and substrate for RubisCO. Functions in an archaeal AMP degradation pathway, together with AMP phosphorylase and RubisCO.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds via a cis-phosphoenolate intermediate.

351160:RCI RS09595
gene id: 351160:RCI_RS09595
uniprot id: Q0W5Q9
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

351160:RCI RS03895
gene id: 351160:RCI_RS03895
uniprot id: Q0W2A2
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

351160:RCI RS01485
gene id: 351160:RCI_RS01485
uniprot id: Q0W0W4
names: Similarity
messages: Belongs to the UPF0305 family.

351160:RCI RS07905
gene id: 351160:RCI_RS07905
uniprot id: Q0W4P3
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

351160:RCI RS15560
gene id: 351160:RCI_RS15560
uniprot id: Q0W940
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

351160:RCI RS06435
gene id: 351160:RCI_RS06435
uniprot id: Q0W3S4
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: Probably part of an ABC transporter complex. Responsible for energy coupling to the transport system.

351160:RCI RS12955
gene id: 351160:RCI_RS12955
uniprot id: Q0W7Q1
names: Subcellular Location Annotation
messages: Membrane

351160:RCI RS02940
gene id: 351160:RCI_RS02940
uniprot id: Q0W1Q4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

351160:RCI RS13975
gene id: 351160:RCI_RS13975
uniprot id: Q0W8A0
names: Similarity
messages: Belongs to the UPF0179 family.

351160:RCI RS06520
gene id: 351160:RCI_RS06520
uniprot id: Q0W3U2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal histone HMF family.
messages: Chromosome
messages: Cytoplasm

351160:RCI RS13335
gene id: 351160:RCI_RS13335
uniprot id: Q0W7X8
names: Function
names: Similarity
messages: Belongs to the eIF-1A family.
messages: Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.

351160:RCI RS14015
gene id: 351160:RCI_RS14015
uniprot id: Q0W8A8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glutaminase PdxT/SNO family.
messages: Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
messages: In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer.

351160:RCI RS12370
gene id: 351160:RCI_RS12370
uniprot id: Q0W7D4
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

351160:RCI RS08430
gene id: 351160:RCI_RS08430
uniprot id: Q0W503
names: Caution
names: Function
names: Similarity
messages: Belongs to the TBP family.
messages: General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

351160:RCI RS12145
gene id: 351160:RCI_RS12145
uniprot id: Q0W788
names: Similarity
messages: Belongs to the UPF0111 family.

351160:RCI RS13985
gene id: 351160:RCI_RS13985
uniprot id: Q0W8A2
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

351160:RCI RS06215
gene id: 351160:RCI_RS06215
uniprot id: Q0W3M8
names: Similarity
messages: Belongs to the aspartokinase family.

351160:RCI RS07220
gene id: 351160:RCI_RS07220
uniprot id: Q0W492
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThiI family.
messages: Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

351160:RCI RS11630
gene id: 351160:RCI_RS11630
uniprot id: Q0W6Y1
names: Similarity
messages: Belongs to the UPF0237 family.

351160:RCI RS10140
gene id: 351160:RCI_RS10140
uniprot id: Q0W622
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

351160:RCI RS14105
gene id: 351160:RCI_RS14105
uniprot id: Q0W8C5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

351160:RCI RS00690
gene id: 351160:RCI_RS00690
uniprot id: Q0W0F8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

351160:RCI RS03675
gene id: 351160:RCI_RS03675
uniprot id: Q0W253
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.

351160:RCI RS09810
gene id: 351160:RCI_RS09810
uniprot id: Q0W5V4
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

351160:RCI RS00030
gene id: 351160:RCI_RS00030
uniprot id: Q0W030
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. Prx6 subfamily.
messages: Cytoplasm
messages: Homodecamer. Pentamer of dimers that assemble into a ring structure.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. Although the primary sequence of this enzyme is similar to those of the 1-Cys Prx6 enzymes, its catalytic properties resemble those of the typical 2-Cys Prxs and C(R) is provided by the other dimeric subunit to form an intersubunit disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

351160:RCI RS05060
gene id: 351160:RCI_RS05060
uniprot id: Q0W2Y8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase PH family. Rrp41 subfamily.
messages: Catalytic component of the exosome, which is a complex involved in RNA degradation. Has 3'->5' exoribonuclease activity. Can also synthesize heteropolymeric RNA-tails.
messages: Component of the archaeal exosome complex. Forms a hexameric ring-like arrangement composed of 3 Rrp41-Rrp42 heterodimers. The hexameric ring associates with a trimer of Rrp4 and/or Csl4 subunits.
messages: Cytoplasm

351160:RCI RS14205
gene id: 351160:RCI_RS14205
uniprot id: Q0W8E4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the beta-RFA-P synthase family.
messages: Catalyzes the condensation of 4-aminobenzoate (pABA) with 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to produce beta-ribofuranosylaminobenzene 5'-phosphate (beta-RFA-P).
messages: Homodimer.

351160:RCI RS05690
gene id: 351160:RCI_RS05690
uniprot id: Q0W3B6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine.
messages: Cytoplasm
messages: Homodimer.

351160:RCI RS10805
gene id: 351160:RCI_RS10805
uniprot id: Q0W6F9
names: Similarity
messages: Belongs to the ComB family.

351160:RCI RS14710
gene id: 351160:RCI_RS14710
uniprot id: Q0W8P0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the aTrm56 family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs.

351160:RCI RS07265
gene id: 351160:RCI_RS07265
uniprot id: Q0W4A2
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

351160:RCI RS12185
gene id: 351160:RCI_RS12185
uniprot id: Q0W796
names: Similarity
messages: Belongs to the UPF0146 family.

351160:RCI RS05835
gene id: 351160:RCI_RS05835
uniprot id: Q0W3E9
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

351160:RCI RS02195
gene id: 351160:RCI_RS02195
uniprot id: Q0W1A0
names: Similarity
messages: Belongs to the Nth/MutY family.

351160:RCI RS14990
gene id: 351160:RCI_RS14990
uniprot id: Q0W8U5
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.

351160:RCI RS14475
gene id: 351160:RCI_RS14475
uniprot id: Q0W8J4
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: Probably part of an ABC transporter complex. Responsible for energy coupling to the transport system.

351160:RCI RS13060
gene id: 351160:RCI_RS13060
uniprot id: Q0W7S2
names: Similarity
messages: Belongs to the TlyA family.

351160:RCI RS08570
gene id: 351160:RCI_RS08570
uniprot id: Q0W534
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

351160:RCI RS10125
gene id: 351160:RCI_RS10125
uniprot id: Q0W619
names: Subcellular Location Annotation
messages: Membrane

351160:RCI RS15040
gene id: 351160:RCI_RS15040
uniprot id: Q0W8V4
names: Subcellular Location Annotation
messages: Membrane

351160:RCI RS08770
gene id: 351160:RCI_RS08770
uniprot id: Q0W588
names: Similarity
messages: In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.
messages: In the central section; belongs to the CRISPR-associated helicase Cas3 family.

351160:RCI RS06680
gene id: 351160:RCI_RS06680
uniprot id: Q0W3X3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HCP family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Binds 1 hybrid [4Fe-2O-2S] cluster.
messages: Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
messages: Cytoplasm

351160:RCI RS05920
gene id: 351160:RCI_RS05920
uniprot id: Q0W3G7
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

351160:RCI RS04350
gene id: 351160:RCI_RS04350
uniprot id: Q0W2J5
names: Similarity
messages: Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.

351160:RCI RS05435
gene id: 351160:RCI_RS05435
uniprot id: Q0W364
names: Function
names: Similarity
messages: Belongs to the V-ATPase F subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

351160:RCI RS07055
gene id: 351160:RCI_RS07055
uniprot id: Q0W454
names: Similarity
messages: Belongs to the desulfoferrodoxin family.

351160:RCI RS12060
gene id: 351160:RCI_RS12060
uniprot id: Q0W770
names: Similarity
messages: Belongs to the peptidase S49 family.

351160:RCI RS01525
gene id: 351160:RCI_RS01525
uniprot id: Q0W0X1
names: Function
names: Similarity
messages: Belongs to the ATP-dependent DNA ligase family.
messages: DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair.

351160:RCI RS03555
gene id: 351160:RCI_RS03555
uniprot id: Q0W228
names: Similarity
messages: Belongs to the alpha-acetolactate decarboxylase family.

351160:RCI RS14110
gene id: 351160:RCI_RS14110
uniprot id: Q0W8C6
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

351160:RCI RS05080
gene id: 351160:RCI_RS05080
uniprot id: Q0W2Z2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic/archaeal RNase P protein component 2 family.
messages: Consists of a catalytic RNA component and at least 4-5 protein subunits.
messages: Cytoplasm
messages: Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.

351160:RCI RS10175
gene id: 351160:RCI_RS10175
uniprot id: Q0W630
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

351160:RCI RS11040
gene id: 351160:RCI_RS11040
uniprot id: Q0W6K8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Aminocarboxypropyltransferase that catalyzes the aminocarboxypropyl transfer on pseudouridine corresponding to position 914 in M.jannaschii 16S rRNA. It constitutes the last step in biosynthesis of the hypermodified N1-methyl-N3-(3-amino-3-carboxypropyl) pseudouridine (m1acp3-Psi).
messages: Belongs to the TDD superfamily. TSR3 family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

351160:RCI RS07200
gene id: 351160:RCI_RS07200
uniprot id: Q0W486
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SepCysS family.
messages: Converts O-phospho-L-seryl-tRNA(Cys) (Sep-tRNA(Cys)) to L-cysteinyl-tRNA(Cys) (Cys-tRNA(Cys)).
messages: Homodimer. Interacts with SepRS.

351160:RCI RS07645
gene id: 351160:RCI_RS07645
uniprot id: Q0W4I7
names: Similarity
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.

351160:RCI RS14315
gene id: 351160:RCI_RS14315
uniprot id: Q0W8G5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Part of the 30S ribosomal subunit.
messages: With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits.

351160:RCI RS09155
gene id: 351160:RCI_RS09155
uniprot id: Q0W5G8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS19 family.
messages: May be involved in maturation of the 30S ribosomal subunit.
messages: Part of the 30S ribosomal subunit.

351160:RCI RS15510
gene id: 351160:RCI_RS15510
uniprot id: Q0W930
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

351160:RCI RS09440
gene id: 351160:RCI_RS09440
uniprot id: Q0W5M8
names: Function
names: Similarity
messages: Belongs to the eukaryotic RecA-like protein family.
messages: Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules.

351160:RCI RS04965
gene id: 351160:RCI_RS04965
uniprot id: Q0W2X0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA 3'-terminal cyclase family. Type 1 subfamily.
messages: Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing.
messages: Cytoplasm

351160:RCI RS08165
gene id: 351160:RCI_RS08165
uniprot id: Q0W4U7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Involved in protein export.
messages: Membrane
messages: Part of the protein translocation apparatus. Forms a complex with SecD.

351160:RCI RS08495
gene id: 351160:RCI_RS08495
uniprot id: Q0W517
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

351160:RCI RS13250
gene id: 351160:RCI_RS13250
uniprot id: Q0W7W0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

351160:RCI RS09705
gene id: 351160:RCI_RS09705
uniprot id: Q0W5T3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm

351160:RCI RS10885
gene id: 351160:RCI_RS10885
uniprot id: Q0W6H4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic release factor 1 family. Pelota subfamily.
messages: Cytoplasm
messages: May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA. May play a role in the release non-functional ribosomes and degradation of damaged mRNAs. Has endoribonuclease activity.
messages: Monomer.
messages: The N-terminal domain has the RNA-binding Sm fold. It harbors the endoribonuclease activity.

351160:RCI RS05525
gene id: 351160:RCI_RS05525
uniprot id: Q0W382
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CbiX family. CbiXS subfamily.
messages: Catalyzes the insertion of Co(2+) into sirohydrochlorin as part of the anaerobic pathway to cobalamin biosynthesis. Involved in the biosynthesis of the unique nickel-containing tetrapyrrole coenzyme F430, the prosthetic group of methyl-coenzyme M reductase (MCR), which plays a key role in methanogenesis and anaerobic methane oxidation. Catalyzes the insertion of Ni(2+) into sirohydrochlorin to yield Ni-sirohydrochlorin.
messages: Homotetramer; dimer of dimers.

351160:RCI RS08995
gene id: 351160:RCI_RS08995
uniprot id: Q0W5D4
names: Function
names: Similarity
messages: Belongs to the eIF-1A family.
messages: Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.

351160:RCI RS12745
gene id: 351160:RCI_RS12745
uniprot id: Q0W7K9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetate uptake transporter (AceTr) (TC 2.A.96) family.
messages: Membrane

351160:RCI RS11570
gene id: 351160:RCI_RS11570
uniprot id: Q0W6W9
names: Subcellular Location Annotation
messages: Membrane

351160:RCI RS11135
gene id: 351160:RCI_RS11135
uniprot id: Q0W6M8
names: Similarity
messages: Belongs to the acylphosphatase family.

351160:RCI RS05330
gene id: 351160:RCI_RS05330
uniprot id: Q0W343
names: Similarity
names: Subunit
messages: Belongs to the methyl-coenzyme M reductase beta subunit family.
messages: Hexamer of two alpha, two beta, and two gamma chains.
messages: MCR is a hexamer of two alpha, two beta, and two gamma chains, forming a dimer of heterotrimers.

351160:RCI RS07300
gene id: 351160:RCI_RS07300
uniprot id: Q0W4A9
names: Subcellular Location Annotation
messages: Membrane

351160:RCI RS04375
gene id: 351160:RCI_RS04375
uniprot id: Q0W2K0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal NMN adenylyltransferase family.
messages: Cytoplasm

351160:RCI RS01760
gene id: 351160:RCI_RS01760
uniprot id: Q0W114
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: Probably part of an ABC transporter complex. Responsible for energy coupling to the transport system.

351160:RCI RS07860
gene id: 351160:RCI_RS07860
uniprot id: Q0W4N4
names: Similarity
messages: Belongs to the HypD family.

351160:RCI RS05665
gene id: 351160:RCI_RS05665
uniprot id: Q0W3B0
names: Similarity
messages: Belongs to the TCP-1 chaperonin family.

351160:RCI RS05190
gene id: 351160:RCI_RS05190
uniprot id: Q0W314
names: Function
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).

351160:RCI RS05305
gene id: 351160:RCI_RS05305
uniprot id: Q0W338
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MtrE family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of a complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step.
messages: The complex is composed of 8 subunits; MtrA, MtrB, MtrC, MtrD, MtrE, MtrF, MtrG and MtrH.

351160:RCI RS07760
gene id: 351160:RCI_RS07760
uniprot id: Q0W4L5
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

351160:RCI RS12990
gene id: 351160:RCI_RS12990
uniprot id: Q0W7Q8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Cytoplasm

351160:RCI RS01865
gene id: 351160:RCI_RS01865
uniprot id: Q0W135
names: Subcellular Location Annotation
messages: Membrane

351160:RCI RS01405
gene id: 351160:RCI_RS01405
uniprot id: Q0W0U7
names: Similarity
messages: Belongs to the HdrB family.

351160:RCI RS04335
gene id: 351160:RCI_RS04335
uniprot id: Q0W2J3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic-type primase large subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Heterodimer of a small subunit (PriS) and a large subunit (PriL).
messages: Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair.

351160:RCI RS01500
gene id: 351160:RCI_RS01500
uniprot id: Q0W0W6
names: Subcellular Location Annotation
messages: Cytoplasm

351160:RCI RS06580
gene id: 351160:RCI_RS06580
uniprot id: Q0W3V4
names: Subcellular Location Annotation
messages: Membrane

351160:RCI RS12090
gene id: 351160:RCI_RS12090
uniprot id: Q0W776
names: Similarity
messages: Belongs to the deoxyhypusine synthase family.

351160:RCI RS02510
gene id: 351160:RCI_RS02510
uniprot id: Q0W1F9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
messages: Cytoplasm
messages: Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.

351160:RCI RS05005
gene id: 351160:RCI_RS05005
uniprot id: Q0W2X7
names: Similarity
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.

351160:RCI RS00135
gene id: 351160:RCI_RS00135
uniprot id: Q0W052
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein P1/P2 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the 50S ribosomal subunit. Homodimer, it forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Forms a heptameric L10(L12)2(L12)2(L12)2 complex, where L10 forms an elongated spine to which the L12 dimers bind in a sequential fashion.

351160:RCI RS09650
gene id: 351160:RCI_RS09650
uniprot id: Q0W5S2
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

351160:RCI RS02380
gene id: 351160:RCI_RS02380
uniprot id: Q0W1D2
names: Cofactor
names: Similarity
messages: Belongs to the ELP3 family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

351160:RCI RS03935
gene id: 351160:RCI_RS03935
uniprot id: Q0W2B0
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.

351160:RCI RS12170
gene id: 351160:RCI_RS12170
uniprot id: Q0W793
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the archaeal DnaG primase family.
messages: Binds two Mg(2+) per subunit.
messages: Forms a ternary complex with MCM helicase and DNA. Component of the archaeal exosome complex.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteromeric, adenine-rich transcripts and the exosome.

351160:RCI RS05785
gene id: 351160:RCI_RS05785
uniprot id: Q0W3D9
names: Subcellular Location Annotation
messages: Membrane

351160:RCI RS14135
gene id: 351160:RCI_RS14135
uniprot id: Q0W8D0
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

351160:RCI RS06995
gene id: 351160:RCI_RS06995
uniprot id: Q0W440
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NifD/NifK/NifE/NifN family.
messages: Tetramer of two alpha and two beta chains. Forms complex with the iron protein (nitrogenase component 2).
messages: This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation.

351160:RCI RS12925
gene id: 351160:RCI_RS12925
uniprot id: Q0W7P5
names: Function
messages: Protects DNA against thermal denaturation and modulates transcription.

351160:RCI RS03335
gene id: 351160:RCI_RS03335
uniprot id: Q0W1Y1
names: Similarity
messages: Belongs to the SUI1 family.

351160:RCI RS11335
gene id: 351160:RCI_RS11335
uniprot id: Q0W6S1
names: Subcellular Location Annotation
messages: Membrane

351160:RCI RS14340
gene id: 351160:RCI_RS14340
uniprot id: Q0W8H0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

351160:RCI RS02480
gene id: 351160:RCI_RS02480
uniprot id: Q0W7U5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

351160:RCI RS01175
gene id: 351160:RCI_RS01175
uniprot id: Q0W0Q2
names: Similarity
messages: Belongs to the SUI1 family.

351160:RCI RS11120
gene id: 351160:RCI_RS11120
uniprot id: Q0W6M5
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

351160:RCI RS15235
gene id: 351160:RCI_RS15235
uniprot id: Q0W8X4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TOP6B family.
messages: Homodimer. Heterotetramer of two Top6A and two Top6B chains.
messages: Relaxes both positive and negative superturns and exhibits a strong decatenase activity.

351160:RCI RS11500
gene id: 351160:RCI_RS11500
uniprot id: Q0W6V5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. CofH family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated synthesis of 5-amino-5-(4-hydroxybenzyl)-6-(D-ribitylimino)-5,6-dihydrouracil from 5-amino-6-(D-ribitylamino)uracil and L-tyrosine.
messages: The FO synthase complex consists of two subunits, CofG and CofH.

351160:RCI RS15120
gene id: 351160:RCI_RS15120
uniprot id: Q0W944
names: Similarity
messages: Belongs to the UPF0288 family.

351160:RCI RS10220
gene id: 351160:RCI_RS10220
uniprot id: Q0W639
names: Subcellular Location Annotation
messages: Membrane

351160:RCI RS13585
gene id: 351160:RCI_RS13585
uniprot id: Q0W827
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

351160:RCI RS14230
gene id: 351160:RCI_RS14230
uniprot id: Q0W8E9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

351160:RCI RS08040
gene id: 351160:RCI_RS08040
uniprot id: Q0W4S0
names: Subcellular Location Annotation
messages: Membrane

351160:RCI RS08550
gene id: 351160:RCI_RS08550
uniprot id: Q0W529
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

351160:RCI RS08205
gene id: 351160:RCI_RS08205
uniprot id: Q0W4V5
names: Subcellular Location Annotation
messages: Membrane

351160:RCI RS00885
gene id: 351160:RCI_RS00885
uniprot id: Q0W0J7
names: Similarity
messages: Belongs to the DNA polymerase type-B family.

351160:RCI RS02910
gene id: 351160:RCI_RS02910
uniprot id: Q0W1P5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.

351160:RCI RS08925
gene id: 351160:RCI_RS08925
uniprot id: Q0W5C1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

351160:RCI RS03885
gene id: 351160:RCI_RS03885
uniprot id: Q0W299
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class III (archaeal) subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

351160:RCI RS04985
gene id: 351160:RCI_RS04985
uniprot id: Q0W2X4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

351160:RCI RS00520
gene id: 351160:RCI_RS00520
uniprot id: Q0W0C4
names: Subcellular Location Annotation
messages: Membrane

351160:RCI RS11480
gene id: 351160:RCI_RS11480
uniprot id: Q0W6V1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CofC family.
messages: Guanylyltransferase that catalyzes the activation of (2S)-2-phospholactate (2-PL) as (2S)-lactyl-2-diphospho-5'-guanosine, via the condensation of 2-PL with GTP. It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor.
messages: Homodimer.

351160:RCI RS14345
gene id: 351160:RCI_RS14345
uniprot id: Q0W8H1
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: Part of the RNA polymerase complex.

351160:RCI RS14335
gene id: 351160:RCI_RS14335
uniprot id: Q0W8G9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds at least 2 Zn(2+) per subunit.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Forms the clamp head domain.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

351160:RCI RS09230
gene id: 351160:RCI_RS09230
uniprot id: Q0W5I2
names: Similarity
names: Subunit
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
messages: Heterooligomer of catalytic and regulatory chains.

351160:RCI RS11435
gene id: 351160:RCI_RS11435
uniprot id: Q0W6U1
names: Similarity
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.

351160:RCI RS06360
gene id: 351160:RCI_RS06360
uniprot id: Q0W3Q7
names: Similarity
messages: Belongs to the transcriptional regulator TrmB family.

351160:RCI RS14470
gene id: 351160:RCI_RS14470
uniprot id: Q0W8J3
names: Subcellular Location Annotation
messages: Membrane

351160:RCI RS02780
gene id: 351160:RCI_RS02780
uniprot id: Q0W1L7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

351160:RCI RS08170
gene id: 351160:RCI_RS08170
uniprot id: Q0W4U8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Involved in protein export.
messages: Membrane
messages: Part of the protein translocation apparatus. Forms a complex with SecF.

351160:RCI RS04415
gene id: 351160:RCI_RS04415
uniprot id: Q0W2K9
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS1 family.

351160:RCI RS10795
gene id: 351160:RCI_RS10795
uniprot id: Q0W6F6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.

351160:RCI RS11105
gene id: 351160:RCI_RS11105
uniprot id: Q0W6M2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

351160:RCI RS05315
gene id: 351160:RCI_RS05315
uniprot id: Q0W340
names: Similarity
names: Subunit
messages: Belongs to the methyl-coenzyme M reductase gamma subunit family.
messages: Hexamer of two alpha, two beta, and two gamma chains.
messages: MCR is a hexamer of two alpha, two beta, and two gamma chains, forming a dimer of heterotrimers.

351160:RCI RS03085
gene id: 351160:RCI_RS03085
uniprot id: Q0W1T2
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

351160:RCI RS04535
gene id: 351160:RCI_RS04535
uniprot id: Q0W2N2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eIF-2-beta/eIF-5 family.
messages: Heterotrimer composed of an alpha, a beta and a gamma chain.
messages: eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA.

351160:RCI RS00935
gene id: 351160:RCI_RS00935
uniprot id: Q0W0K8
names: Subcellular Location Annotation
messages: Membrane

351160:RCI RS04545
gene id: 351160:RCI_RS04545
uniprot id: Q0W2N4
names: Subcellular Location Annotation
messages: Membrane

351160:RCI RS10195
gene id: 351160:RCI_RS10195
uniprot id: Q0W634
names: Subcellular Location Annotation
messages: Membrane

351160:RCI RS04515
gene id: 351160:RCI_RS04515
uniprot id: Q0W2M8
names: Similarity
messages: Belongs to the AAA ATPase family.

351160:RCI RS10960
gene id: 351160:RCI_RS10960
uniprot id: Q0W6J0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HdrA family.
messages: Cytoplasm
messages: Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B).
messages: The ferredoxin:CoB-CoM heterodisulfide reductase is composed of three subunits; HdrA, HdrB and HdrC.

351160:RCI RS03365
gene id: 351160:RCI_RS03365
uniprot id: Q0W1Y7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: Binds to 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29.

351160:RCI RS04585
gene id: 351160:RCI_RS04585
uniprot id: Q0W2P2
names: Similarity
messages: Belongs to the protein kinase superfamily. BUD32 family.

351160:RCI RS10415
gene id: 351160:RCI_RS10415
uniprot id: Q0W676
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

351160:RCI RS10035
gene id: 351160:RCI_RS10035
uniprot id: Q0W600
names: Subcellular Location Annotation
messages: Membrane

351160:RCI RS00990
gene id: 351160:RCI_RS00990
uniprot id: Q0W0L7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

351160:RCI RS01345
gene id: 351160:RCI_RS01345
uniprot id: Q0W0T5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endonuclease V family.
messages: Cytoplasm
messages: DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA.

351160:RCI RS04540
gene id: 351160:RCI_RS04540
uniprot id: Q0W2N3
names: Similarity
messages: Belongs to the MCM family.

351160:RCI RS09540
gene id: 351160:RCI_RS09540
uniprot id: Q0W5P8
names: Function
names: Similarity
messages: Belongs to the archaeal SPP-like hydrolase family.
messages: Catalyzes the dephosphorylation of 2-phosphoglycolate.

351160:RCI RS01465
gene id: 351160:RCI_RS01465
uniprot id: Q0W0W0
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

351160:RCI RS01750
gene id: 351160:RCI_RS01750
uniprot id: Q0W112
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the transcriptional regulatory CopG/NikR family.
messages: Binds 1 nickel ion per subunit.
messages: Transcriptional regulator.

351160:RCI RS00300
gene id: 351160:RCI_RS00300
uniprot id: Q0W083
names: Similarity
messages: Belongs to the HerA family.

351160:RCI RS11260
gene id: 351160:RCI_RS11260
uniprot id: Q0W6Q4
names: Cofactor
names: Similarity
messages: Belongs to the GARS family.
messages: Binds 2 magnesium or manganese ions per subunit.

351160:RCI RS02755
gene id: 351160:RCI_RS02755
uniprot id: Q0W1L1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the archaeosine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs.

351160:RCI RS03325
gene id: 351160:RCI_RS03325
uniprot id: Q0W1X9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

351160:RCI RS02805
gene id: 351160:RCI_RS02805
uniprot id: Q0W1M2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DeoC/FbaB aldolase family. ADHS subfamily.
messages: Catalyzes a transaldol reaction between 6-deoxy-5-ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids.
messages: Homodecamer.

351160:RCI RS13080
gene id: 351160:RCI_RS13080
uniprot id: Q0W7S6
names: Similarity
messages: Belongs to the glutamate synthase family.

351160:RCI RS14255
gene id: 351160:RCI_RS14255
uniprot id: Q0W8F4
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

351160:RCI RS02220
gene id: 351160:RCI_RS02220
uniprot id: Q0W1A5
names: Similarity
messages: Belongs to the DMRL synthase family.

351160:RCI RS11155
gene id: 351160:RCI_RS11155
uniprot id: Q0W6N2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

351160:RCI RS11515
gene id: 351160:RCI_RS11515
uniprot id: Q0W6V8
names: Similarity
messages: Belongs to the tRNA(His) guanylyltransferase family.

351160:RCI RS00770
gene id: 351160:RCI_RS00770
uniprot id: Q0W0H5
names: Similarity
messages: Belongs to the SIS family. PHI subfamily.

351160:RCI RS05095
gene id: 351160:RCI_RS05095
uniprot id: Q0W2Z5
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL15 family.

351160:RCI RS04265
gene id: 351160:RCI_RS04265
uniprot id: Q0W2I0
names: Subcellular Location Annotation
messages: Membrane

351160:RCI RS03415
gene id: 351160:RCI_RS03415
uniprot id: Q0W1Z9
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

351160:RCI RS07855
gene id: 351160:RCI_RS07855
uniprot id: Q0W4N3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

351160:RCI RS15585
gene id: 351160:RCI_RS15585
uniprot id: Q0W0C2
names: Subcellular Location Annotation
messages: Membrane

351160:RCI RS02495
gene id: 351160:RCI_RS02495
uniprot id: Q0W1F6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

351160:RCI RS07295
gene id: 351160:RCI_RS07295
uniprot id: Q0W4A8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the archaeal dihydroneopterin aldolase family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin (H2Neo) to 6-hydroxymethyl-7,8-dihydropterin (6-HMD).
messages: Homotetramer.

351160:RCI RS11815
gene id: 351160:RCI_RS11815
uniprot id: Q0W720
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

351160:RCI RS04455
gene id: 351160:RCI_RS04455
uniprot id: Q0W2L6
names: Function
names: Similarity
messages: Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).

351160:RCI RS14155
gene id: 351160:RCI_RS14155
uniprot id: Q0W8D4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IPP isomerase type 2 family.
messages: Cytoplasm
messages: Homooctamer. Dimer of tetramers.
messages: Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

351160:RCI RS05040
gene id: 351160:RCI_RS05040
uniprot id: Q0W2Y4
names: Similarity
messages: Belongs to the CTAG/PCC1 family.

351160:RCI RS14600
gene id: 351160:RCI_RS14600
uniprot id: Q0W8M0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic-type primase small subunit family.
messages: Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair.
messages: Heterodimer of a small subunit (PriS) and a large subunit (PriL).

351160:RCI RS05280
gene id: 351160:RCI_RS05280
uniprot id: Q0W333
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MtrA family.
messages: Binds 1 5-hydroxybenzimidazolylcobamide group.
messages: Cell membrane
messages: Part of a complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step.
messages: The complex is composed of 8 subunits; MtrA, MtrB, MtrC, MtrD, MtrE, MtrF, MtrG and MtrH.

351160:RCI RS07940
gene id: 351160:RCI_RS07940
uniprot id: Q0W4Q0
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
messages: Cytoplasm
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Non-allosteric.

351160:RCI RS00865
gene id: 351160:RCI_RS00865
uniprot id: Q0W0J3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

351160:RCI RS13170
gene id: 351160:RCI_RS13170
uniprot id: Q05HF3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

351160:RCI RS01510
gene id: 351160:RCI_RS01510
uniprot id: Q0W0W8
names: Similarity
messages: Belongs to the AOR/FOR family.

351160:RCI RS09360
gene id: 351160:RCI_RS09360
uniprot id: Q0W5K9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

351160:RCI RS01765
gene id: 351160:RCI_RS01765
uniprot id: Q0W115
names: Subunit
messages: Homodimer.

351160:RCI RS06365
gene id: 351160:RCI_RS06365
uniprot id: Q0W3Q8
names: Subcellular Location Annotation
messages: Membrane

351160:RCI RS00310
gene id: 351160:RCI_RS00310
uniprot id: Q0W085
names: Function
names: Similarity
names: Subunit
messages: Belongs to the diphthine synthase family.
messages: Homodimer.
messages: S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the trimethylation of the amino group of the modified target histidine residue in translation elongation factor 2 (EF-2), to form an intermediate called diphthine. The three successive methylation reactions represent the second step of diphthamide biosynthesis.

351160:RCI RS14635
gene id: 351160:RCI_RS14635
uniprot id: Q0W8M8
names: Similarity
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.

351160:RCI RS00425
gene id: 351160:RCI_RS00425
uniprot id: Q0W0A6
names: Subcellular Location Annotation
messages: Membrane

351160:RCI RS03195
gene id: 351160:RCI_RS03195
uniprot id: Q0W1V4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit.

351160:RCI RS12400
gene id: 351160:RCI_RS12400
uniprot id: Q0W7E0
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the L-aspartate dehydrogenase family.
messages: Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate.
messages: The iminoaspartate product is unstable in aqueous solution and can decompose to oxaloacetate and ammonia.

351160:RCI RS01365
gene id: 351160:RCI_RS01365
uniprot id: Q0W0T9
names: Similarity
messages: Belongs to the LeuD family. LeuD type 2 subfamily.

351160:RCI RS10410
gene id: 351160:RCI_RS10410
uniprot id: Q0W675
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

351160:RCI RS05725
gene id: 351160:RCI_RS05725
uniprot id: Q0W3C5
names: Subcellular Location Annotation
messages: Membrane

351160:RCI RS07980
gene id: 351160:RCI_RS07980
uniprot id: Q0W4R0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DtxR/MntR family.
messages: Cytoplasm
messages: Homodimer.

351160:RCI RS10910
gene id: 351160:RCI_RS10910
uniprot id: Q0W6I0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the XPG/RAD2 endonuclease family. FEN1 subfamily.
messages: Binds 2 magnesium ions per subunit. They probably participate in the reaction catalyzed by the enzyme. May bind an additional third magnesium ion after substrate binding.
messages: Interacts with PCNA. PCNA stimulates the nuclease activity without altering cleavage specificity.
messages: Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. Acts as a genome stabilization factor that prevents flaps from equilibrating into structures that lead to duplications and deletions. Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA (By similarity).

351160:RCI RS11495
gene id: 351160:RCI_RS11495
uniprot id: Q0W6V4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. CofH family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated synthesis of 5-amino-5-(4-hydroxybenzyl)-6-(D-ribitylimino)-5,6-dihydrouracil from 5-amino-6-(D-ribitylamino)uracil and L-tyrosine.
messages: Consists of two subunits, CofG and CofH.

351160:RCI RS11095
gene id: 351160:RCI_RS11095
uniprot id: Q0W6M0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease activity. May be involved in RNA degradation.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Archaeal RNase J subfamily.
messages: Binds 2 Zn(2+) ions per subunit. It is not clear if Zn(2+) or Mg(2+) is physiologically important.
messages: Cytoplasm
messages: Homodimer.

351160:RCI RS07110
gene id: 351160:RCI_RS07110
uniprot id: Q0W468
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Heterodimer composed of a glutamine amidotransferase subunit (A) and a GMP-binding subunit (B).

351160:RCI RS08960
gene id: 351160:RCI_RS08960
uniprot id: Q0W5C8
names: Similarity
messages: Belongs to the DNA glycosylase MPG family.

351160:RCI RS05125
gene id: 351160:RCI_RS05125
uniprot id: Q0W302
names: Function
names: Similarity
messages: Belongs to the TFIIB family.
messages: Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB).

351160:RCI RS03295
gene id: 351160:RCI_RS03295
uniprot id: Q0W1X3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit.

351160:RCI RS06670
gene id: 351160:RCI_RS06670
uniprot id: Q0W3X1
names: Similarity
messages: Belongs to the peptidase S33 family.

351160:RCI RS06645
gene id: 351160:RCI_RS06645
uniprot id: Q0W3W6
names: Subcellular Location Annotation
messages: Membrane

351160:RCI RS14395
gene id: 351160:RCI_RS14395
uniprot id: Q0W8H9
names: Subcellular Location Annotation
messages: Membrane

351160:RCI RS03725
gene id: 351160:RCI_RS03725
uniprot id: Q0W263
names: Subcellular Location Annotation
messages: Membrane

351160:RCI RS04195
gene id: 351160:RCI_RS04195
uniprot id: Q0W2G5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

351160:RCI RS01100
gene id: 351160:RCI_RS01100
uniprot id: Q0W0N8
names: Similarity
messages: Belongs to the AdoMet synthase family.

351160:RCI RS10155
gene id: 351160:RCI_RS10155
uniprot id: Q0W626
names: Similarity
messages: Belongs to the anthranilate synthase component I family.

351160:RCI RS11240
gene id: 351160:RCI_RS11240
uniprot id: Q0W6Q0
names: Similarity
messages: Belongs to the HypE family.

351160:RCI RS15240
gene id: 351160:RCI_RS15240
uniprot id: Q0W8X5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TOP6A family.
messages: Homodimer. Heterotetramer of two Top6A and two Top6B chains.
messages: Relaxes both positive and negative superturns and exhibits a strong decatenase activity.

351160:RCI RS00570
gene id: 351160:RCI_RS00570
uniprot id: Q0W0D5
names: Function
messages: Part of a potassium transport system.

351160:RCI RS15225
gene id: 351160:RCI_RS15225
uniprot id: Q0W8X2
names: Function
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2.

351160:RCI RS14720
gene id: 351160:RCI_RS14720
uniprot id: Q0W8P2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CSL4 family.
messages: Component of the archaeal exosome complex. Forms a trimer of Rrp4 and/or Csl4 subunits. The trimer associates with an hexameric ring-like arrangement composed of 3 Rrp41-Rrp42 heterodimers. Interacts with DnaG.
messages: Cytoplasm
messages: Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs.

351160:RCI RS00685
gene id: 351160:RCI_RS00685
uniprot id: Q0W0F7
names: Similarity
messages: Belongs to the P(II) protein family.

351160:RCI RS05455
gene id: 351160:RCI_RS05455
uniprot id: Q0W368
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Membrane

351160:RCI RS15550
gene id: 351160:RCI_RS15550
uniprot id: Q0W938
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Part of the 30S ribosomal subunit.

351160:RCI RS08635
gene id: 351160:RCI_RS08635
uniprot id: Q0W546
names: Similarity
messages: Belongs to the AAA ATPase family.

351160:RCI RS05345
gene id: 351160:RCI_RS05345
uniprot id: Q0W346
names: Similarity
messages: Belongs to the class-I fumarase family.

351160:RCI RS04695
gene id: 351160:RCI_RS04695
uniprot id: Q0W2R5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

351160:RCI RS00545
gene id: 351160:RCI_RS00545
uniprot id: Q0W0D0
names: Similarity
messages: Belongs to the pirin family.

351160:RCI RS08860
gene id: 351160:RCI_RS08860
uniprot id: Q0W5A8
names: Function
names: Similarity
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. Type 2 subfamily.
messages: Catalyzes the conversion of AMP and phosphate to adenine and ribose 1,5-bisphosphate (R15P). Exhibits phosphorylase activity toward CMP and UMP in addition to AMP. Functions in an archaeal AMP degradation pathway, together with R15P isomerase and RubisCO.

351160:RCI RS03970
gene id: 351160:RCI_RS03970
uniprot id: Q0W2B7
names: Subcellular Location Annotation
messages: Membrane

351160:RCI RS08605
gene id: 351160:RCI_RS08605
uniprot id: Q0W540
names: Subcellular Location Annotation
messages: Membrane

351160:RCI RS12165
gene id: 351160:RCI_RS12165
uniprot id: Q0W792
names: Similarity
messages: Belongs to the UPF0292 family.

351160:RCI RS01285
gene id: 351160:RCI_RS01285
uniprot id: Q0W0S3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

351160:RCI RS04980
gene id: 351160:RCI_RS04980
uniprot id: Q0W2X3
names: Function
names: Similarity
messages: Belongs to the BPG-independent phosphoglycerate mutase family. A-PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

351160:RCI RS09465
gene id: 351160:RCI_RS09465
uniprot id: Q0W5N3
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

351160:RCI RS03355
gene id: 351160:RCI_RS03355
uniprot id: Q0W1Y5
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

351160:RCI RS00240
gene id: 351160:RCI_RS00240
uniprot id: Q0W073
names: Similarity
messages: Belongs to the TCP-1 chaperonin family.

351160:RCI RS03685
gene id: 351160:RCI_RS03685
uniprot id: Q0W255
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

351160:RCI RS13550
gene id: 351160:RCI_RS13550
uniprot id: Q0W821
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.
messages: Catalyzes the condensation of pyruvate and acetyl-coenzyme A to form (R)-citramalate.
messages: Homodimer.

351160:RCI RS00700
gene id: 351160:RCI_RS00700
uniprot id: Q0W0G0
names: Similarity
messages: Belongs to the DEAD box helicase family.

351160:RCI RS04170
gene id: 351160:RCI_RS04170
uniprot id: Q0W2G0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methyltransferase superfamily. TrmY family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically catalyzes the N1-methylation of pseudouridine at position 54 (Psi54) in tRNAs.

351160:RCI RS07340
gene id: 351160:RCI_RS07340
uniprot id: Q0W4B8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-I 3-dehydroquinase family.
messages: Homodimer.
messages: Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate.

351160:RCI RS10965
gene id: 351160:RCI_RS10965
uniprot id: Q0W6J1
names: Similarity
messages: Belongs to the HdrB family.

351160:RCI RS00650
gene id: 351160:RCI_RS00650
uniprot id: Q0W0F0
names: Caution
names: Function
names: Similarity
messages: Belongs to the Nre family.
messages: Involved in DNA damage repair.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

351160:RCI RS11230
gene id: 351160:RCI_RS11230
uniprot id: Q0W6P8
names: Similarity
messages: Belongs to the HupF/HypC family.

351160:RCI RS09570
gene id: 351160:RCI_RS09570
uniprot id: Q0W5Q4
names: Similarity
messages: Belongs to the HerA family.

351160:RCI RS10550
gene id: 351160:RCI_RS10550
uniprot id: Q0W6A5
names: Subcellular Location Annotation
messages: Membrane

351160:RCI RS07875
gene id: 351160:RCI_RS07875
uniprot id: Q0W4N6
names: Function
names: Similarity
messages: Belongs to the EF-1-beta/EF-1-delta family.
messages: Promotes the exchange of GDP for GTP in EF-1-alpha/GDP, thus allowing the regeneration of EF-1-alpha/GTP that could then be used to form the ternary complex EF-1-alpha/GTP/AAtRNA.

351160:RCI RS05065
gene id: 351160:RCI_RS05065
uniprot id: Q0W2Y9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RRP4 family.
messages: Component of the archaeal exosome complex. Forms a trimer of Rrp4 and/or Csl4 subunits. The trimer associates with an hexameric ring-like arrangement composed of 3 Rrp41-Rrp42 heterodimers.
messages: Cytoplasm
messages: Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Confers strong poly(A) specificity to the exosome.

351160:RCI RS08795
gene id: 351160:RCI_RS08795
uniprot id: Q0W595
names: Similarity
messages: Belongs to the carbamoyltransferase HypF family.

351160:RCI RS10615
gene id: 351160:RCI_RS10615
uniprot id: Q0W6B9
names: Function
names: Similarity
messages: Belongs to the MfnB family.
messages: Catalyzes the formation of 4-(hydroxymethyl)-2-furancarboxaldehyde phosphate (4-HFC-P) from two molecules of glyceraldehyde-3-P (GA-3-P).

351160:RCI RS13070
gene id: 351160:RCI_RS13070
uniprot id: Q0W7S4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

351160:RCI RS05565
gene id: 351160:RCI_RS05565
uniprot id: Q0W390
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eIF-2-beta/eIF-5 family.
messages: Heterotrimer composed of an alpha, a beta and a gamma chain.
messages: eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA.

351160:RCI RS04405
gene id: 351160:RCI_RS04405
uniprot id: Q0W2K6
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

351160:RCI RS00115
gene id: 351160:RCI_RS00115
uniprot id: Q0W048
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SPT5 family.
messages: Belongs to the archaeal Spt5 family.
messages: Heterodimer composed of Spt4 and Spt5. Interacts with RNA polymerase (RNAP).
messages: Stimulates transcription elongation.

351160:RCI RS00335
gene id: 351160:RCI_RS00335
uniprot id: Q0W089
names: Subcellular Location Annotation
messages: Membrane

351160:RCI RS10850
gene id: 351160:RCI_RS10850
uniprot id: Q0W6G8
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. PoK subfamily.
messages: Phosphorylates (R)-pantoate to form (R)-4-phosphopantoate in the CoA biosynthesis pathway.

351160:RCI RS12405
gene id: 351160:RCI_RS12405
uniprot id: Q0W7E1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NadC/ModD family.
messages: Hexamer formed by 3 homodimers.
messages: Involved in the catabolism of quinolinic acid (QA).

351160:RCI RS14485
gene id: 351160:RCI_RS14485
uniprot id: Q0W8J6
names: Subcellular Location Annotation
messages: Membrane

351160:RCI RS02385
gene id: 351160:RCI_RS02385
uniprot id: Q0W1D3
names: Similarity
messages: Belongs to the peptidase M24B family.

351160:RCI RS02900
gene id: 351160:RCI_RS02900
uniprot id: Q0W1P3
names: Function
messages: Decarboxylates L-threonine-O-3-phosphate to yield (R)-1-amino-2-propanol O-2-phosphate, the precursor for the linkage between the nucleotide loop and the corrin ring in cobalamin.

351160:RCI RS14045
gene id: 351160:RCI_RS14045
uniprot id: Q0W8B4
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS6 family.

351160:RCI RS02490
gene id: 351160:RCI_RS02490
uniprot id: Q0W1F5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane

351160:RCI RS15045
gene id: 351160:RCI_RS15045
uniprot id: Q0W8V5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the beta-RFA-P synthase family.
messages: Catalyzes the condensation of 4-aminobenzoate (pABA) with 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to produce beta-ribofuranosylaminobenzene 5'-phosphate (beta-RFA-P).
messages: Homodimer.

351160:RCI RS14140
gene id: 351160:RCI_RS14140
uniprot id: Q0W8D1
names: Similarity
messages: Belongs to the MEMO1 family.

351160:RCI RS15565
gene id: 351160:RCI_RS15565
uniprot id: Q0W941
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eIF-5A family.
messages: Cytoplasm
messages: Functions by promoting the formation of the first peptide bond.

351160:RCI RS03245
gene id: 351160:RCI_RS03245
uniprot id: Q0W1W3
names: Subcellular Location Annotation
messages: Membrane

351160:RCI RS06295
gene id: 351160:RCI_RS06295
uniprot id: Q0W3P4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the activator 1 small subunits family. RfcL subfamily.
messages: Heteromultimer composed of small subunits (RfcS) and large subunits (RfcL).
messages: Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA.

351160:RCI RS06340
gene id: 351160:RCI_RS06340
uniprot id: Q0W3Q3
names: Similarity
messages: Belongs to the transcriptional regulator TrmB family.

351160:RCI RS05290
gene id: 351160:RCI_RS05290
uniprot id: Q0W335
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MtrB family.
messages: Cell membrane
messages: Membrane
messages: Part of a complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step.
messages: The complex is composed of 8 subunits; MtrA, MtrB, MtrC, MtrD, MtrE, MtrF, MtrG and MtrH.

351160:RCI RS13535
gene id: 351160:RCI_RS13535
uniprot id: Q0W818
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STT3 family.
messages: Membrane

351160:RCI RS04615
gene id: 351160:RCI_RS04615
uniprot id: Q0W2P8
names: Function
names: Similarity
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.

351160:RCI RS13955
gene id: 351160:RCI_RS13955
uniprot id: Q0W896
names: Function
names: Similarity
names: Subunit
messages: Belongs to the threonine synthase family. Cysteate synthase subfamily.
messages: Homotrimer.
messages: Specifically catalyzes the beta-elimination of phosphate from L-phosphoserine and the beta-addition of sulfite to the dehydroalanine intermediate to produce L-cysteate.

351160:RCI RS12440
gene id: 351160:RCI_RS12440
uniprot id: Q0W7E8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

351160:RCI RS13830
gene id: 351160:RCI_RS13830
uniprot id: Q0W873
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

351160:RCI RS14305
gene id: 351160:RCI_RS14305
uniprot id: Q0W8G3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

351160:RCI RS00120
gene id: 351160:RCI_RS00120
uniprot id: Q0W049
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

351160:RCI RS01150
gene id: 351160:RCI_RS01150
uniprot id: Q0W0P7
names: Subcellular Location Annotation
messages: Membrane

351160:RCI RS12085
gene id: 351160:RCI_RS12085
uniprot id: Q0W775
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

351160:RCI RS14185
gene id: 351160:RCI_RS14185
uniprot id: Q0W8E0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PyrK family.
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Heterotetramer of 2 PyrK and 2 PyrD type B subunits.
messages: Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+).

351160:RCI RS01530
gene id: 351160:RCI_RS01530
uniprot id: Q0W0X4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 2 subfamily.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

351160:RCI RS07985
gene id: 351160:RCI_RS07985
uniprot id: Q0W4R1
names: Subcellular Location Annotation
messages: Membrane

351160:RCI RS05085
gene id: 351160:RCI_RS05085
uniprot id: Q0W2Z3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic/archaeal RNase P protein component 3 family.
messages: Consists of a catalytic RNA component and at least 4-5 protein subunits.
messages: Cytoplasm
messages: Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.

351160:RCI RS13865
gene id: 351160:RCI_RS13865
uniprot id: Q0W880
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CdhD family.
messages: Heterodimer of delta and gamma chains. The ACDS complex is made up of alpha, epsilon, beta, gamma and delta chains with a probable stoichiometry of (alpha(2)epsilon(2))(4)-beta(8)-(gamma(1)delta(1))(8).
messages: Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing autotrophic growth from CO(2). Probably maintains the overall quaternary structure of the ACDS complex.

351160:RCI RS07665
gene id: 351160:RCI_RS07665
uniprot id: Q0W4J1
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL40 family.

351160:RCI RS05285
gene id: 351160:RCI_RS05285
uniprot id: Q0W334
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MtrA family.
messages: Binds 1 5-hydroxybenzimidazolylcobamide group.
messages: Cell membrane
messages: Part of a complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step.
messages: The complex is composed of 8 subunits; MtrA, MtrB, MtrC, MtrD, MtrE, MtrF, MtrG and MtrH.

351160:RCI RS08110
gene id: 351160:RCI_RS08110
uniprot id: Q0W4T6
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

351160:RCI RS04370
gene id: 351160:RCI_RS04370
uniprot id: Q0W2J9
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

351160:RCI RS03955
gene id: 351160:RCI_RS03955
uniprot id: Q0W2B4
names: Similarity
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.

351160:RCI RS13970
gene id: 351160:RCI_RS13970
uniprot id: Q0W899
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HdrA family.
messages: Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B).
messages: The ferredoxin:CoB-CoM heterodisulfide reductase is composed of three subunits; HdrA, HdrB and HdrC.

351160:RCI RS05830
gene id: 351160:RCI_RS05830
uniprot id: Q0W3E8
names: Similarity
messages: Belongs to the HisA/HisF family.

351160:RCI RS15945
gene id: 351160:RCI_RS15945
uniprot id: Q0W7B6
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

351160:RCI RS03985
gene id: 351160:RCI_RS03985
uniprot id: Q0W2C0
names: Similarity
messages: Belongs to the FrhG family.

351160:RCI RS11900
gene id: 351160:RCI_RS11900
uniprot id: Q0W737
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
messages: Homodimer.

351160:RCI RS04040
gene id: 351160:RCI_RS04040
uniprot id: Q0W2D2
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Although this enzyme belongs to the family of MTA phosphorylases based on sequence homology, it has been shown that conserved amino acid substitutions in the substrate binding pocket convert the substrate specificity of this enzyme from 6-aminopurines to 6-oxopurines.
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Homohexamer. Dimer of a homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Purine nucleoside phosphorylase which is highly specific for 6-oxopurine nucleosides. Cleaves guanosine or inosine to respective bases and sugar-1-phosphate molecules. Involved in purine salvage.

351160:RCI RS12495
gene id: 351160:RCI_RS12495
uniprot id: Q0W7G0
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.
messages: Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

351160:RCI RS07115
gene id: 351160:RCI_RS07115
uniprot id: Q0W469
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

351160:RCI RS02130
gene id: 351160:RCI_RS02130
uniprot id: Q0W188
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

351160:RCI RS08130
gene id: 351160:RCI_RS08130
uniprot id: Q0W4U0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Archaeal shikimate kinase subfamily.
messages: Cytoplasm

351160:RCI RS07660
gene id: 351160:RCI_RS07660
uniprot id: Q0W4J0
names: Similarity
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.

351160:RCI RS05195
gene id: 351160:RCI_RS05195
uniprot id: Q0W315
names: Similarity
messages: Belongs to the AOR/FOR family.

351160:RCI RS01215
gene id: 351160:RCI_RS01215
uniprot id: Q0W0R1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

351160:RCI RS02590
gene id: 351160:RCI_RS02590
uniprot id: Q0W1H5
names: Subcellular Location Annotation
messages: Membrane

351160:RCI RS07775
gene id: 351160:RCI_RS07775
uniprot id: Q0W4L8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Homodimer.
messages: Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.

351160:RCI RS08665
gene id: 351160:RCI_RS08665
uniprot id: Q0W552
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A single active site specifically recognizes both ATP and CTP and is responsible for their addition.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Archaeal CCA-adding enzyme subfamily.
messages: Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.
messages: Homodimer.

351160:RCI RS08365
gene id: 351160:RCI_RS08365
uniprot id: Q0W4Z0
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

351160:RCI RS04960
gene id: 351160:RCI_RS04960
uniprot id: Q0W2W9
names: Function
names: Similarity
messages: Belongs to the KptA/TPT1 family.
messages: Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP-ribose 1''-2''-cyclic phosphate (APPR>P). May function as an ADP-ribosylase.

351160:RCI RS07140
gene id: 351160:RCI_RS07140
uniprot id: Q0W474
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.

351160:RCI RS14430
gene id: 351160:RCI_RS14430
uniprot id: Q0W8I5
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily.

351160:RCI RS01090
gene id: 351160:RCI_RS01090
uniprot id: Q0W0N6
names: Similarity
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.

351160:RCI RS14240
gene id: 351160:RCI_RS14240
uniprot id: Q0W8F1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

351160:RCI RS14565
gene id: 351160:RCI_RS14565
uniprot id: Q0W8L2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 2 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm

351160:RCI RS07085
gene id: 351160:RCI_RS07085
uniprot id: Q0W461
names: Subcellular Location Annotation
messages: Membrane

351160:RCI RS06840
gene id: 351160:RCI_RS06840
uniprot id: Q0W409
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

351160:RCI RS09715
gene id: 351160:RCI_RS09715
uniprot id: Q0W5T5
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

351160:RCI RS02875
gene id: 351160:RCI_RS02875
uniprot id: Q0W1N7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

351160:RCI RS11530
gene id: 351160:RCI_RS11530
uniprot id: Q0W6W1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

351160:RCI RS12230
gene id: 351160:RCI_RS12230
uniprot id: Q0W7A2
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate.
messages: Belongs to the GatB/GatE family. GatE subfamily.
messages: Heterodimer of GatD and GatE.

351160:RCI RS10405
gene id: 351160:RCI_RS10405
uniprot id: Q0W674
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS17 family.

351160:RCI RS11085
gene id: 351160:RCI_RS11085
uniprot id: Q0W6L7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

351160:RCI RS09655
gene id: 351160:RCI_RS09655
uniprot id: Q0W5S3
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

351160:RCI RS03795
gene id: 351160:RCI_RS03795
uniprot id: Q0W278
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

351160:RCI RS11590
gene id: 351160:RCI_RS11590
uniprot id: Q0W6X3
names: Similarity
messages: Belongs to the peptidase U62 family.

351160:RCI RS04865
gene id: 351160:RCI_RS04865
uniprot id: Q0W2V3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

351160:RCI RS03270
gene id: 351160:RCI_RS03270
uniprot id: Q0W1W8
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Part of the 30S ribosomal subunit. Contacts protein S4.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

351160:RCI RS06150
gene id: 351160:RCI_RS06150
uniprot id: Q0W3L4
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

351160:RCI RS11715
gene id: 351160:RCI_RS11715
uniprot id: Q0W700
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Heterodimer composed of a glutamine amidotransferase subunit (A) and a GMP-binding subunit (B).

351160:RCI RS08420
gene id: 351160:RCI_RS08420
uniprot id: Q0W501
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Membrane

351160:RCI RS15970
gene id: 351160:RCI_RS15970
uniprot id: Q0W7K4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

351160:RCI RS05390
gene id: 351160:RCI_RS05390
uniprot id: Q0W355
names: Similarity
messages: Belongs to the thymidylate kinase family.

351160:RCI RS02835
gene id: 351160:RCI_RS02835
uniprot id: Q0W1M9
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

351160:RCI RS10555
gene id: 351160:RCI_RS10555
uniprot id: Q0W6A6
names: Subcellular Location Annotation
messages: Membrane

351160:RCI RS05025
gene id: 351160:RCI_RS05025
uniprot id: Q0W2Y1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0014 family.
messages: Membrane

351160:RCI RS04975
gene id: 351160:RCI_RS04975
uniprot id: Q0W2X2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: S-layer

351160:RCI RS09830
gene id: 351160:RCI_RS09830
uniprot id: Q0W5V8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Forms a complex with TatA.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.

351160:RCI RS11220
gene id: 351160:RCI_RS11220
uniprot id: Q0W6P6
names: Caution
names: Function
names: Similarity
messages: Belongs to the Nre family.
messages: Involved in DNA damage repair.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

351160:RCI RS12515
gene id: 351160:RCI_RS12515
uniprot id: Q0W7G4
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.

351160:RCI RS04120
gene id: 351160:RCI_RS04120
uniprot id: Q0W2E9
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL21 family.

351160:RCI RS04075
gene id: 351160:RCI_RS04075
uniprot id: Q0W2E0
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.

351160:RCI RS07650
gene id: 351160:RCI_RS07650
uniprot id: Q0W4I8
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

351160:RCI RS00830
gene id: 351160:RCI_RS00830
uniprot id: Q0W0I6
names: Cofactor
names: Function
names: Subunit
messages: Binds 2 [4Fe-4S] clusters. In this family the first cluster has a non-standard and varying [4Fe-4S] binding motif CX(2)CX(2)CX(4-5)CP.
messages: Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.
messages: Heterodimer of the IorA and IorB subunits.

351160:RCI RS02365
gene id: 351160:RCI_RS02365
uniprot id: Q0W1C9
names: Similarity
messages: Belongs to the UPF0047 family.

351160:RCI RS09635
gene id: 351160:RCI_RS09635
uniprot id: Q0W5R8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

351160:RCI RS03635
gene id: 351160:RCI_RS03635
uniprot id: Q0W245
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ferredoxin thioredoxin reductase beta subunit family.
messages: Catalytic subunit of the ferredoxin-thioredoxin reductase (FTR), which catalyzes the two-electron reduction of thioredoxins by the electrons provided by reduced ferredoxin.
messages: Heterodimer of subunit A (variable subunit) and subunit B (catalytic subunit). Heterodimeric FTR forms a complex with ferredoxin and thioredoxin.

351160:RCI RS03240
gene id: 351160:RCI_RS03240
uniprot id: Q0W1W2
names: Subcellular Location Annotation
messages: Membrane

351160:RCI RS10770
gene id: 351160:RCI_RS10770
uniprot id: Q0W6F1
names: Subcellular Location Annotation
messages: Membrane

351160:RCI RS03680
gene id: 351160:RCI_RS03680
uniprot id: Q0W254
names: Caution
names: Function
names: Similarity
messages: Belongs to the adenylate kinase family. AK6 subfamily.
messages: Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

351160:RCI RS05320
gene id: 351160:RCI_RS05320
uniprot id: Q0W341
names: Subunit
messages: MCR is composed of three subunits: alpha, beta, and gamma. The function of proteins C and D is not known.

351160:RCI RS11550
gene id: 351160:RCI_RS11550
uniprot id: Q0W6W5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

351160:RCI RS10120
gene id: 351160:RCI_RS10120
uniprot id: Q0W618
names: Subcellular Location Annotation
messages: Membrane

351160:RCI RS06430
gene id: 351160:RCI_RS06430
uniprot id: Q0W3S3
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: Probably part of an ABC transporter complex. Responsible for energy coupling to the transport system.

351160:RCI RS02905
gene id: 351160:RCI_RS02905
uniprot id: Q0W1P4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

351160:RCI RS15285
gene id: 351160:RCI_RS15285
uniprot id: Q0W8Y4
names: Subcellular Location Annotation
messages: Membrane

351160:RCI RS03345
gene id: 351160:RCI_RS03345
uniprot id: Q0W1Y3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head.
messages: Part of the 30S ribosomal subunit.

351160:RCI RS14780
gene id: 351160:RCI_RS14780
uniprot id: Q0W8Q4
names: Similarity
messages: Belongs to the SIS family. PHI subfamily.

351160:RCI RS05110
gene id: 351160:RCI_RS05110
uniprot id: Q0W2Z9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SRP19 family.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds directly to 7S RNA and mediates binding of the 54 kDa subunit of the SRP.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. Archaeal SRP consists of a 7S RNA molecule of 300 nucleotides and two protein subunits: SRP54 and SRP19.

351160:RCI RS05030
gene id: 351160:RCI_RS05030
uniprot id: Q0W2Y2
names: Similarity
messages: Belongs to the UPF0440 family.

351160:RCI RS03010
gene id: 351160:RCI_RS03010
uniprot id: Q0W1R8
names: Similarity
messages: Belongs to the RuvC family.

351160:RCI RS09180
gene id: 351160:RCI_RS09180
uniprot id: Q0W5H2
names: Function
names: Similarity
messages: Belongs to the eIF-6 family.
messages: Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex.

351160:RCI RS08730
gene id: 351160:RCI_RS08730
uniprot id: Q0W565
names: Subcellular Location Annotation
messages: Membrane

351160:RCI RS03265
gene id: 351160:RCI_RS03265
uniprot id: Q0W1W7
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

351160:RCI RS02860
gene id: 351160:RCI_RS02860
uniprot id: Q0W1N4
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.

351160:RCI RS06110
gene id: 351160:RCI_RS06110
uniprot id: Q0W3K6
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.

351160:RCI RS12665
gene id: 351160:RCI_RS12665
uniprot id: Q0W7J2
names: Function
messages: Part of a potassium transport system.

351160:RCI RS05035
gene id: 351160:RCI_RS05035
uniprot id: Q0W2Y3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the prefoldin subunit beta family.
messages: Cytoplasm
messages: Heterohexamer of two alpha and four beta subunits.
messages: Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding.

351160:RCI RS14585
gene id: 351160:RCI_RS14585
uniprot id: Q0W8L6
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 2 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

351160:RCI RS10500
gene id: 351160:RCI_RS10500
uniprot id: Q0W694
names: Similarity
messages: Belongs to the UPF0200 family.
messages: Belongs to the UPF0201 family.

351160:RCI RS11165
gene id: 351160:RCI_RS11165
uniprot id: Q0W6N3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

351160:RCI RS04215
gene id: 351160:RCI_RS04215
uniprot id: Q0W2G9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal histone HMF family.
messages: Chromosome
messages: Cytoplasm

351160:RCI RS11320
gene id: 351160:RCI_RS11320
uniprot id: Q0W6R8
names: Subcellular Location Annotation
messages: Cell membrane

351160:RCI RS06480
gene id: 351160:RCI_RS06480
uniprot id: Q0W3T3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

351160:RCI RS05510
gene id: 351160:RCI_RS05510
uniprot id: Q0W379
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

351160:RCI RS04355
gene id: 351160:RCI_RS04355
uniprot id: Q0W2J6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

351160:RCI RS11870
gene id: 351160:RCI_RS11870
uniprot id: Q0W731
names: Similarity
messages: Belongs to the MtxX family.

351160:RCI RS14975
gene id: 351160:RCI_RS14975
uniprot id: Q0W8U2
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

351160:RCI RS15460
gene id: 351160:RCI_RS15460
uniprot id: Q0W920
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

351160:RCI RS08340
gene id: 351160:RCI_RS08340
uniprot id: Q0W4Y5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Forms a complex with TatA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.

351160:RCI RS14840
gene id: 351160:RCI_RS14840
uniprot id: Q0W8R6
names: Similarity
messages: Belongs to the ZPR1 family.

351160:RCI RS05310
gene id: 351160:RCI_RS05310
uniprot id: Q0W339
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the methyl-coenzyme M reductase alpha subunit family.
messages: Binds 2 coenzyme F430 non-covalently per MCR complex. Coenzyme F430 is a yellow nickel porphinoid. Methyl-coenzyme-M reductase is activated when the enzyme-bound coenzyme F430 is reduced to the Ni(I) oxidation state.
messages: Component of the methyl-coenzyme M reductase (MCR) I that catalyzes the reductive cleavage of methyl-coenzyme M (CoM-S-CH3 or 2-(methylthio)ethanesulfonate) using coenzyme B (CoB or 7-mercaptoheptanoylthreonine phosphate) as reductant which results in the production of methane and the mixed heterodisulfide of CoB and CoM (CoM-S-S-CoB). This is the final step in methanogenesis.
messages: Hexamer of two alpha, two beta, and two gamma chains.
messages: MCR is a hexamer of two alpha, two beta, and two gamma chains, forming a dimer of heterotrimers.

351160:RCI RS14145
gene id: 351160:RCI_RS14145
uniprot id: Q0W8D2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GHMP kinase family. Mevalonate kinase subfamily.
messages: Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)-mevalonate 5-phosphate (MVAP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids.
messages: Cytoplasm
messages: Homodimer.

351160:RCI RS10465
gene id: 351160:RCI_RS10465
uniprot id: Q0W684
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Homodimer.

351160:RCI RS12310
gene id: 351160:RCI_RS12310
uniprot id: Q0W7C2
names: Subcellular Location Annotation
messages: Membrane

351160:RCI RS05420
gene id: 351160:RCI_RS05420
uniprot id: Q0W361
names: Function
names: Similarity
messages: Belongs to the V-ATPase D subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

351160:RCI RS13195
gene id: 351160:RCI_RS13195
uniprot id: Q0W7V0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

351160:RCI RS03260
gene id: 351160:RCI_RS03260
uniprot id: Q0W1W6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

351160:RCI RS10170
gene id: 351160:RCI_RS10170
uniprot id: Q0W629
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

351160:RCI RS01805
gene id: 351160:RCI_RS01805
uniprot id: Q0W123
names: Similarity
messages: Belongs to the deoxyhypusine synthase family.

351160:RCI RS10835
gene id: 351160:RCI_RS10835
uniprot id: Q0W6G5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the archaeal Spt4 family.
messages: Heterodimer composed of Spt4 and Spt5.
messages: Stimulates transcription elongation.

351160:RCI RS14620
gene id: 351160:RCI_RS14620
uniprot id: Q0W8M4
names: Similarity
messages: Belongs to the eIF-2-alpha family.

351160:RCI RS02935
gene id: 351160:RCI_RS02935
uniprot id: Q0W1Q3
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

351160:RCI RS05485
gene id: 351160:RCI_RS05485
uniprot id: Q0W373
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic RPB7/RPC8 RNA polymerase subunit family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Forms 2 domains with an elongated structure; Rpo4 packs into the hinge region between the 2 domains.
messages: Nucleus
messages: Part of the RNA polymerase complex. Forms a stalk with Rpo4 that extends from the main structure.

351160:RCI RS13835
gene id: 351160:RCI_RS13835
uniprot id: Q0W874
names: Function
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.

351160:RCI RS05560
gene id: 351160:RCI_RS05560
uniprot id: Q0W389
names: Similarity
messages: Belongs to the universal ribosomal protein uL16 family.

351160:RCI RS10265
gene id: 351160:RCI_RS10265
uniprot id: Q0W648
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

351160:RCI RS04315
gene id: 351160:RCI_RS04315
uniprot id: Q0W2J0
names: Subcellular Location Annotation
messages: Membrane

351160:RCI RS01955
gene id: 351160:RCI_RS01955
uniprot id: Q0W153
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

351160:RCI RS04440
gene id: 351160:RCI_RS04440
uniprot id: Q0W2L3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SepCysS family.
messages: Converts O-phospho-L-seryl-tRNA(Cys) (Sep-tRNA(Cys)) to L-cysteinyl-tRNA(Cys) (Cys-tRNA(Cys)).
messages: Homodimer. Interacts with SepRS.

351160:RCI RS05655
gene id: 351160:RCI_RS05655
uniprot id: Q0W3A8
names: Similarity
messages: Belongs to the methylamine corrinoid protein family.

351160:RCI RS15160
gene id: 351160:RCI_RS15160
uniprot id: Q0W952
names: Similarity
names: Subunit
messages: Belongs to the HTP reductase family.
messages: Homodimer.

351160:RCI RS12235
gene id: 351160:RCI_RS12235
uniprot id: Q0W7A3
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate.
messages: Belongs to the asparaginase 1 family. GatD subfamily.
messages: Heterodimer of GatD and GatE.

351160:RCI RS11285
gene id: 351160:RCI_RS11285
uniprot id: Q0W6Q9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Monomer.

351160:RCI RS14860
gene id: 351160:RCI_RS14860
uniprot id: Q0W8S0
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

351160:RCI RS05700
gene id: 351160:RCI_RS05700
uniprot id: Q0W3B8
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

351160:RCI RS07680
gene id: 351160:RCI_RS07680
uniprot id: Q0W4J5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA.
messages: Belongs to the TiaS family.
messages: Cytoplasm

351160:RCI RS10365
gene id: 351160:RCI_RS10365
uniprot id: Q0W669
names: Similarity
messages: Belongs to the CutA family.

351160:RCI RS01960
gene id: 351160:RCI_RS01960
uniprot id: Q0W154
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Cytoplasm

351160:RCI RS01400
gene id: 351160:RCI_RS01400
uniprot id: Q0W0U6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HdrA family.
messages: Cytoplasm
messages: Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B).
messages: The ferredoxin:CoB-CoM heterodisulfide reductase is composed of three subunits; HdrA, HdrB and HdrC.

351160:RCI RS13175
gene id: 351160:RCI_RS13175
uniprot id: Q0W7U6
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

351160:RCI RS06170
gene id: 351160:RCI_RS06170
uniprot id: Q0W3L9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Membrane

351160:RCI RS14310
gene id: 351160:RCI_RS14310
uniprot id: Q0W8G4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center.
messages: Part of the 30S ribosomal subunit.

351160:RCI RS13450
gene id: 351160:RCI_RS13450
uniprot id: Q0W801
names: Subcellular Location Annotation
messages: Membrane

351160:RCI RS04115
gene id: 351160:RCI_RS04115
uniprot id: Q0W2E8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic RPB4 RNA polymerase subunit family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. This subunit is less well bound than the others.
messages: Part of the RNA polymerase complex. Forms a stalk with Rpo7 that extends from the main structure.

351160:RCI RS03975
gene id: 351160:RCI_RS03975
uniprot id: Q0W2B8
names: Subcellular Location Annotation
messages: Membrane

351160:RCI RS15520
gene id: 351160:RCI_RS15520
uniprot id: Q0W932
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

351160:RCI RS01770
gene id: 351160:RCI_RS01770
uniprot id: Q0W116
names: Subcellular Location Annotation
messages: Membrane

351160:RCI RS09585
gene id: 351160:RCI_RS09585
uniprot id: Q0W5Q7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamine synthetase family.
messages: Cytoplasm

351160:RCI RS05050
gene id: 351160:RCI_RS05050
uniprot id: Q0W2Y6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL43 family. Putative zinc-binding subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

351160:RCI RS03840
gene id: 351160:RCI_RS03840
uniprot id: Q0W289
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 3 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

351160:RCI RS13555
gene id: 351160:RCI_RS13555
uniprot id: Q0W822
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

351160:RCI RS14210
gene id: 351160:RCI_RS14210
uniprot id: Q0W8E5
names: Similarity
messages: Belongs to the NOP5/NOP56 family.

351160:RCI RS14100
gene id: 351160:RCI_RS14100
uniprot id: Q0W8C4
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL18 family.

351160:RCI RS00005
gene id: 351160:RCI_RS00005
uniprot id: Q0W025
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

351160:RCI RS09900
gene id: 351160:RCI_RS09900
uniprot id: Q0W5X2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

351160:RCI RS11340
gene id: 351160:RCI_RS11340
uniprot id: Q0W6S2
names: Subcellular Location Annotation
messages: Membrane

351160:RCI RS03275
gene id: 351160:RCI_RS03275
uniprot id: Q0W1W9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

351160:RCI RS14215
gene id: 351160:RCI_RS14215
uniprot id: Q0W8E6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the methyltransferase superfamily. Fibrillarin family.
messages: Interacts with nop5. Component of box C/D small ribonucleoprotein (sRNP) particles that contain rpl7ae, FlpA and nop5, plus a guide RNA.
messages: Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA.

351160:RCI RS08850
gene id: 351160:RCI_RS08850
uniprot id: Q0W5A6
names: Function
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Glucose 1-dehydrogenase subfamily.
messages: Catalyzes the NAD(P)(+)-dependent oxidation of D-glucose to D-gluconate via gluconolactone. Can utilize both NAD(+) and NADP(+) as electron acceptor. Is involved in the degradation of glucose through a non-phosphorylative variant of the Entner-Doudoroff pathway.

351160:RCI RS10595
gene id: 351160:RCI_RS10595
uniprot id: Q0W6B5
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

351160:RCI RS01550
gene id: 351160:RCI_RS01550
uniprot id: Q0W0X9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

351160:RCI RS08290
gene id: 351160:RCI_RS08290
uniprot id: Q0W4X2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: S-layer

351160:RCI RS05010
gene id: 351160:RCI_RS05010
uniprot id: Q0W2X8
names: Similarity
messages: Belongs to the FrhG family.

351160:RCI RS04385
gene id: 351160:RCI_RS04385
uniprot id: Q0W2K2
names: Similarity
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.

351160:RCI RS06440
gene id: 351160:RCI_RS06440
uniprot id: Q0W3S5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

351160:RCI RS14825
gene id: 351160:RCI_RS14825
uniprot id: Q0W8R3
names: Similarity
messages: Belongs to the UPF0107 family.

351160:RCI RS10890
gene id: 351160:RCI_RS10890
uniprot id: Q0W6H5
names: Function
names: Similarity
names: Subunit
messages: Associates with stalled 50S ribosomal subunits.
messages: Belongs to the NEMF family.
messages: Probably part of the ribosome quality control system (RQC). May mediate the addition of alanine residues (Ala tailing) to incompletely synthesized nascent chains from stalled ribosomes, leading to their degradation.

351160:RCI RS00125
gene id: 351160:RCI_RS00125
uniprot id: Q0W050
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. Probably involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of its operon by binding to its mRNA.

351160:RCI RS02520
gene id: 351160:RCI_RS02520
uniprot id: Q0W1G1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCH family.
messages: Catalyzes the reversible interconversion of 5-formyl-H(4)MPT to methenyl-H(4)MPT(+).
messages: Cytoplasm

351160:RCI RS03670
gene id: 351160:RCI_RS03670
uniprot id: Q0W252
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase may regulate its activity.
messages: Belongs to the histone-like Alba family.
messages: Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes.
messages: Chromosome
messages: Cytoplasm
messages: Homotetramer.

351160:RCI RS06135
gene id: 351160:RCI_RS06135
uniprot id: Q0W3L1
names: Function
names: Similarity
messages: Belongs to the CDC6/cdc18 family.
messages: Involved in regulation of DNA replication.

351160:RCI RS03310
gene id: 351160:RCI_RS03310
uniprot id: Q0W1X6
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS4 family.

351160:RCI RS00595
gene id: 351160:RCI_RS00595
uniprot id: Q0W0E0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CofD family.
messages: Catalyzes the transfer of the 2-phospholactate moiety from (2S)-lactyl-2-diphospho-5'-guanosine to 7,8-didemethyl-8-hydroxy-5-deazariboflavin (FO) with the formation of oxidized coenzyme F420-0 and GMP.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

351160:RCI RS02775
gene id: 351160:RCI_RS02775
uniprot id: Q0W1L5
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS8 family.
messages: Part of the 30S ribosomal subunit.

351160:RCI RS07250
gene id: 351160:RCI_RS07250
uniprot id: Q0W499
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

351160:RCI RS12520
gene id: 351160:RCI_RS12520
uniprot id: Q0W7G5
names: Similarity
messages: Belongs to the glycosyltransferase 2 family.

351160:RCI RS14610
gene id: 351160:RCI_RS14610
uniprot id: Q0W8M2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL42 family.
messages: Binds 1 zinc ion per subunit.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

351160:RCI RS03965
gene id: 351160:RCI_RS03965
uniprot id: Q0W2B6
names: Subcellular Location Annotation
messages: Membrane

351160:RCI RS12855
gene id: 351160:RCI_RS12855
uniprot id: Q0W7N1
names: Subcellular Location Annotation
messages: Membrane

351160:RCI RS02485
gene id: 351160:RCI_RS02485
uniprot id: Q0W1F4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

351160:RCI RS11170
gene id: 351160:RCI_RS11170
uniprot id: Q0W6N4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M32 family.
messages: Binds 1 zinc ion per subunit.
messages: Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues.

351160:RCI RS14890
gene id: 351160:RCI_RS14890
uniprot id: Q0W8S5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.

351160:RCI RS01820
gene id: 351160:RCI_RS01820
uniprot id: Q0W126
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NucS endonuclease family.
messages: Cleaves both 3' and 5' ssDNA extremities of branched DNA structures.
messages: Cytoplasm

351160:RCI RS05275
gene id: 351160:RCI_RS05275
uniprot id: Q0W332
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MtrG family.
messages: Cell membrane
messages: Part of a complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step.
messages: The complex is composed of 8 subunits; MtrA, MtrB, MtrC, MtrD, MtrE, MtrF, MtrG and MtrH.

351160:RCI RS11395
gene id: 351160:RCI_RS11395
uniprot id: Q0W6T3
names: Subcellular Location Annotation
messages: Membrane

351160:RCI RS06005
gene id: 351160:RCI_RS06005
uniprot id: Q0W3I4
names: Subcellular Location Annotation
messages: Membrane

351160:RCI RS00930
gene id: 351160:RCI_RS00930
uniprot id: Q0W0K7
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

351160:RCI RS04475
gene id: 351160:RCI_RS04475
uniprot id: Q0W2M0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

351160:RCI RS06860
gene id: 351160:RCI_RS06860
uniprot id: Q0W413
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Membrane

351160:RCI RS03760
gene id: 351160:RCI_RS03760
uniprot id: Q0W5A4
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

351160:RCI RS13380
gene id: 351160:RCI_RS13380
uniprot id: Q0W7Y6
names: Subcellular Location Annotation
messages: Membrane

351160:RCI RS03765
gene id: 351160:RCI_RS03765
uniprot id: Q0W272
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

351160:RCI RS02050
gene id: 351160:RCI_RS02050
uniprot id: Q0W172
names: Similarity
messages: Belongs to the HerA family.

351160:RCI RS04105
gene id: 351160:RCI_RS04105
uniprot id: Q0W2E6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

351160:RCI RS02545
gene id: 351160:RCI_RS02545
uniprot id: Q0W1G6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

351160:RCI RS01565
gene id: 351160:RCI_RS01565
uniprot id: Q0W0Y2
names: Subcellular Location Annotation
messages: Membrane

351160:RCI RS03200
gene id: 351160:RCI_RS03200
uniprot id: Q0W1V5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

351160:RCI RS05625
gene id: 351160:RCI_RS05625
uniprot id: Q0W3A2
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

351160:RCI RS01845
gene id: 351160:RCI_RS01845
uniprot id: Q0W131
names: Function
names: Similarity
messages: Belongs to the archaeal-type DHQ synthase family.
messages: Catalyzes the oxidative deamination and cyclization of 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonic acid (ADH) to yield 3-dehydroquinate (DHQ), which is fed into the canonical shikimic pathway of aromatic amino acid biosynthesis.

351160:RCI RS03390
gene id: 351160:RCI_RS03390
uniprot id: Q0W1Z4
names: Similarity
messages: Belongs to the Nth/MutY family.

351160:RCI RS01790
gene id: 351160:RCI_RS01790
uniprot id: Q0W120
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

351160:RCI RS10830
gene id: 351160:RCI_RS10830
uniprot id: Q0W6G4
names: Function
names: Similarity
messages: Belongs to the GTP-dependent DPCK family.
messages: Catalyzes the GTP-dependent phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (CoA).

351160:RCI RS01755
gene id: 351160:RCI_RS01755
uniprot id: Q0W113
names: Subcellular Location Annotation
messages: Membrane

351160:RCI RS07715
gene id: 351160:RCI_RS07715
uniprot id: Q0W4K5
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

351160:RCI RS09805
gene id: 351160:RCI_RS09805
uniprot id: Q0W5V3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM19 family.
messages: Membrane

351160:RCI RS10660
gene id: 351160:RCI_RS10660
uniprot id: Q0W6C9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

351160:RCI RS11140
gene id: 351160:RCI_RS11140
uniprot id: Q0W6M9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
messages: Cytoplasm
messages: Homotetramer.

351160:RCI RS06230
gene id: 351160:RCI_RS06230
uniprot id: Q0W3N1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

351160:RCI RS09700
gene id: 351160:RCI_RS09700
uniprot id: Q0W5T2
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

351160:RCI RS02225
gene id: 351160:RCI_RS02225
uniprot id: Q0W1A6
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

351160:RCI RS15210
gene id: 351160:RCI_RS15210
uniprot id: Q0W8X0
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS28 family.

351160:RCI RS03995
gene id: 351160:RCI_RS03995
uniprot id: Q0W2C2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FNT transporter (TC 2.A.44) family.
messages: Membrane

351160:RCI RS08150
gene id: 351160:RCI_RS08150
uniprot id: Q0W4U4
names: Similarity
messages: Belongs to the thymidylate kinase family.

351160:RCI RS06950
gene id: 351160:RCI_RS06950
uniprot id: Q0W431
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

351160:RCI RS10275
gene id: 351160:RCI_RS10275
uniprot id: Q0W650
names: Similarity
messages: Belongs to the DeoC/FbaB aldolase family.

351160:RCI RS14810
gene id: 351160:RCI_RS14810
uniprot id: Q0W8R0
names: Similarity
messages: Belongs to the TCP-1 chaperonin family.

351160:RCI RS14245
gene id: 351160:RCI_RS14245
uniprot id: Q0W8F2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

351160:RCI RS12160
gene id: 351160:RCI_RS12160
uniprot id: Q0W791
names: Similarity
messages: Belongs to the UPF0235 family.

351160:RCI RS12660
gene id: 351160:RCI_RS12660
uniprot id: Q0W7J1
names: Subcellular Location Annotation
messages: Membrane

351160:RCI RS10600
gene id: 351160:RCI_RS10600
uniprot id: Q0W6B6
names: Similarity
messages: Belongs to the AAA ATPase family. CDC48 subfamily.

351160:RCI RS14495
gene id: 351160:RCI_RS14495
uniprot id: Q0W8J8
names: Subcellular Location Annotation
messages: Membrane

351160:RCI RS05055
gene id: 351160:RCI_RS05055
uniprot id: Q0W2Y7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase PH family. Rrp42 subfamily.
messages: Component of the archaeal exosome complex. Forms a hexameric ring-like arrangement composed of 3 Rrp41-Rrp42 heterodimers. The hexameric ring associates with a trimer of Rrp4 and/or Csl4 subunits.
messages: Cytoplasm
messages: Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Contributes to the structuring of the Rrp41 active site.

351160:RCI RS02725
gene id: 351160:RCI_RS02725
uniprot id: Q0W1K5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIB subfamily.
messages: Cell inner membrane
messages: Mediates magnesium influx to the cytosol.

351160:RCI RS13620
gene id: 351160:RCI_RS13620
uniprot id: Q0W834
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.

351160:RCI RS05450
gene id: 351160:RCI_RS05450
uniprot id: Q0W367
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Membrane

351160:RCI RS06160
gene id: 351160:RCI_RS06160
uniprot id: Q0W3L6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

351160:RCI RS05475
gene id: 351160:RCI_RS05475
uniprot id: Q0W371
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EIF2G subfamily.
messages: Heterotrimer composed of an alpha, a beta and a gamma chain.
messages: eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA.

351160:RCI RS08215
gene id: 351160:RCI_RS08215
uniprot id: Q0W4V7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

351160:RCI RS07065
gene id: 351160:RCI_RS07065
uniprot id: Q0W456
names: Caution
names: Function
names: Similarity
messages: Belongs to the ornithine cyclodeaminase/mu-crystallin family. Archaeal alanine dehydrogenase subfamily.
messages: Catalyzes the NAD(+)-dependent oxidative deamination of L-alanine to pyruvate, and the reverse reaction, the reductive amination of pyruvate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

351160:RCI RS06495
gene id: 351160:RCI_RS06495
uniprot id: Q0W3T6
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

351160:RCI RS13460
gene id: 351160:RCI_RS13460
uniprot id: Q0W803
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STT3 family.
messages: Membrane

351160:RCI RS12950
gene id: 351160:RCI_RS12950
uniprot id: Q0W7Q0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

351160:RCI RS15615
gene id: 351160:RCI_RS15615
uniprot id: Q0W104
names: Subcellular Location Annotation
messages: Membrane

351160:RCI RS05545
gene id: 351160:RCI_RS05545
uniprot id: Q0W386
names: Domain
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the CobB/CbiA family.
messages: Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source. Involved in the biosynthesis of the unique nickel-containing tetrapyrrole coenzyme F430, the prosthetic group of methyl-coenzyme M reductase (MCR), which plays a key role in methanogenesis and anaerobic methane oxidation. Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of Ni-sirohydrochlorin, using L-glutamine or ammonia as the nitrogen source.
messages: Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP, and cobyrinate or Ni-sirohydrochlorin, and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.
messages: The a and c carboxylates of cobyrinate and Ni-sirohydrochlorin are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CbiA catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate.

351160:RCI RS03235
gene id: 351160:RCI_RS03235
uniprot id: Q0W1W1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 2 subfamily.
messages: Cytoplasm

351160:RCI RS14150
gene id: 351160:RCI_RS14150
uniprot id: Q0W8D3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the isopentenyl phosphate kinase family.
messages: Catalyzes the formation of isopentenyl diphosphate (IPP), the building block of all isoprenoids.
messages: Homodimer.

351160:RCI RS13600
gene id: 351160:RCI_RS13600
uniprot id: Q0W830
names: Similarity
messages: Belongs to the UPF0251 family.

351160:RCI RS07910
gene id: 351160:RCI_RS07910
uniprot id: Q0W4P4
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

351160:RCI RS12750
gene id: 351160:RCI_RS12750
uniprot id: Q0W7L0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

351160:RCI RS13035
gene id: 351160:RCI_RS13035
uniprot id: Q0W7R7
names: Subcellular Location Annotation
messages: Membrane

351160:RCI RS07835
gene id: 351160:RCI_RS07835
uniprot id: Q0W4M8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycerol-1-phosphate dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea.
messages: Cytoplasm

351160:RCI RS06705
gene id: 351160:RCI_RS06705
uniprot id: Q0W3X9
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged L-seryl-tRNA(Thr).
messages: Cytoplasm
messages: Homodimer.
messages: The N-terminal domain is an archaea-specific tRNA-editing domain that hydrolyzes incorrectly charged L-seryl-tRNA(Thr). Catalysis of tRNA editing is performed by the charged tRNA itself.

351160:RCI RS12435
gene id: 351160:RCI_RS12435
uniprot id: Q0W7E7
names: Subcellular Location Annotation
messages: Membrane

351160:RCI RS06965
gene id: 351160:RCI_RS06965
uniprot id: Q0W434
names: Similarity
messages: Belongs to the tRNA methyltransferase O family.

351160:RCI RS14115
gene id: 351160:RCI_RS14115
uniprot id: Q0W8C7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal Rpo10/eukaryotic RPB10 RNA polymerase subunit family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

351160:RCI RS13840
gene id: 351160:RCI_RS13840
uniprot id: Q0W875
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

351160:RCI RS02390
gene id: 351160:RCI_RS02390
uniprot id: Q0W1D4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase archaeal type 2 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).

351160:RCI RS05045
gene id: 351160:RCI_RS05045
uniprot id: Q0W2Y5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal Rpo12/eukaryotic RPC10 RNA polymerase subunit family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

351160:RCI RS09190
gene id: 351160:RCI_RS09190
uniprot id: Q0W5H4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the prefoldin subunit alpha family.
messages: Cytoplasm
messages: Heterohexamer of two alpha and four beta subunits.
messages: Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding.

351160:RCI RS02470
gene id: 351160:RCI_RS02470
uniprot id: Q0W1F1
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

351160:RCI RS09160
gene id: 351160:RCI_RS09160
uniprot id: Q0W5G9
names: Similarity
messages: Belongs to the PDCD5 family.

351160:RCI RS15320
gene id: 351160:RCI_RS15320
uniprot id: Q0W8Z1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

351160:RCI RS02210
gene id: 351160:RCI_RS02210
uniprot id: Q0W1A3
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

351160:RCI RS01335
gene id: 351160:RCI_RS01335
uniprot id: Q0W0T3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

351160:RCI RS06660
gene id: 351160:RCI_RS06660
uniprot id: Q0W3W9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

351160:RCI RS01700
gene id: 351160:RCI_RS01700
uniprot id: Q0W106
names: Subcellular Location Annotation
messages: Membrane

351160:RCI RS03290
gene id: 351160:RCI_RS03290
uniprot id: Q0W1X2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

351160:RCI RS05360
gene id: 351160:RCI_RS05360
uniprot id: Q0W349
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the geranylgeranyl reductase family. DGGGPL reductase subfamily.
messages: Binds 1 FAD per subunit.
messages: Is involved in the reduction of 2,3-digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains.
messages: Reduction reaction proceeds via syn addition of hydrogen for double bonds.

351160:RCI RS07655
gene id: 351160:RCI_RS07655
uniprot id: Q0W4I9
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

351160:RCI RS07320
gene id: 351160:RCI_RS07320
uniprot id: Q0W4B4
names: Subcellular Location Annotation
messages: Membrane

351160:RCI RS10245
gene id: 351160:RCI_RS10245
uniprot id: Q0W644
names: Function
names: Similarity
messages: Catalyzes the condensation of formaldehyde with tetrahydromethanopterin (H(4)MPT) to 5,10-methylenetetrahydromethanopterin.
messages: Catalyzes the reversible formation of ribulose-5-phosphate and formaldehyde from 3-hexulose-6-phosphate.
messages: In the C-terminal section; belongs to the HPS/KGPDC family. HPS subfamily.
messages: In the N-terminal section; belongs to the formaldehyde-activating enzyme family.

351160:RCI RS05295
gene id: 351160:RCI_RS05295
uniprot id: Q0W336
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MtrC family.
messages: Cell membrane
messages: Membrane
messages: Part of a complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step.
messages: The complex is composed of 8 subunits; MtrA, MtrB, MtrC, MtrD, MtrE, MtrF, MtrG and MtrH.

351160:RCI RS08660
gene id: 351160:RCI_RS08660
uniprot id: Q0W551
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

351160:RCI RS01555
gene id: 351160:RCI_RS01555
uniprot id: Q0W0Y0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

351160:RCI RS14835
gene id: 351160:RCI_RS14835
uniprot id: Q0W8R5
names: Similarity
messages: Belongs to the UPF0284 family.

351160:RCI RS01660
gene id: 351160:RCI_RS01660
uniprot id: Q0W0Z8
names: Similarity
messages: Belongs to the peptidase S8 family.

351160:RCI RS14095
gene id: 351160:RCI_RS14095
uniprot id: Q0W8C3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

351160:RCI RS08740
gene id: 351160:RCI_RS08740
uniprot id: Q0W582
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

351160:RCI RS05855
gene id: 351160:RCI_RS05855
uniprot id: Q0W3F3
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

351160:RCI RS10070
gene id: 351160:RCI_RS10070
uniprot id: Q0W607
names: Subcellular Location Annotation
messages: Membrane

351160:RCI RS01370
gene id: 351160:RCI_RS01370
uniprot id: Q0W0U0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

351160:RCI RS10000
gene id: 351160:RCI_RS10000
uniprot id: Q0W5Z3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

351160:RCI RS13210
gene id: 351160:RCI_RS13210
uniprot id: Q0W7V3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

351160:RCI RS10610
gene id: 351160:RCI_RS10610
uniprot id: Q0W6B8
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

351160:RCI RS04635
gene id: 351160:RCI_RS04635
uniprot id: Q0W2Q3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

351160:RCI RS04125
gene id: 351160:RCI_RS04125
uniprot id: Q0W2F0
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase Pus10 family.
messages: Responsible for synthesis of pseudouridine from uracil-54 and uracil-55 in the psi GC loop of transfer RNAs.

351160:RCI RS07235
gene id: 351160:RCI_RS07235
uniprot id: Q0W496
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. Archaeal HPRT subfamily.
messages: Catalyzes a salvage reaction resulting in the formation of IMP that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

351160:RCI RS11100
gene id: 351160:RCI_RS11100
uniprot id: Q0W6M1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mer family.
messages: Catalyzes the reversible reduction of methylene-H(4)MPT to methyl-H(4)MPT.
messages: Cytoplasm

351160:RCI RS03230
gene id: 351160:RCI_RS03230
uniprot id: Q0W1W0
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 2 subfamily.
messages: Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

351160:RCI RS00710
gene id: 351160:RCI_RS00710
uniprot id: Q0W0G2
names: Similarity
messages: In the N-terminal section; belongs to the zinc metallo-hydrolase group 3 family.

351160:RCI RS14855
gene id: 351160:RCI_RS14855
uniprot id: Q0W8R9
names: Similarity
messages: Belongs to the snRNP Sm proteins family.

351160:RCI RS14380
gene id: 351160:RCI_RS14380
uniprot id: Q0W8H6
names: Caution
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

351160:RCI RS13560
gene id: 351160:RCI_RS13560
uniprot id: Q0W823
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

351160:RCI RS15125
gene id: 351160:RCI_RS15125
uniprot id: Q0W945
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

351160:RCI RS11310
gene id: 351160:RCI_RS11310
uniprot id: Q0W6R5
names: Subcellular Location Annotation
messages: Cytoplasm

351160:RCI RS11280
gene id: 351160:RCI_RS11280
uniprot id: Q0W6Q8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Reduced FMN (FMNH(2)).

351160:RCI RS14190
gene id: 351160:RCI_RS14190
uniprot id: Q0W8E1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with NAD(+) as electron acceptor.
messages: Cytoplasm
messages: Heterotetramer of 2 PyrK and 2 PyrD type B subunits.

351160:RCI RS14700
gene id: 351160:RCI_RS14700
uniprot id: Q0W8N8
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TFE family.
messages: Monomer. Interaction with RNA polymerase subunits RpoF and RpoE is necessary for Tfe stimulatory transcription activity. Able to interact with Tbp and RNA polymerase in the absence of DNA promoter. Interacts both with the preinitiation and elongation complexes.
messages: The winged helix domain is involved in binding to DNA in the preinitiation complex.
messages: Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes. Seems to translocate with the RNA polymerase following initiation and acts by binding to the non template strand of the transcription bubble in elongation complexes.

351160:RCI RS10580
gene id: 351160:RCI_RS10580
uniprot id: Q0W6B2
names: Similarity
messages: Belongs to the AAA ATPase family. CDC48 subfamily.

351160:RCI RS09175
gene id: 351160:RCI_RS09175
uniprot id: Q0W5H1
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL31 family.

351160:RCI RS03190
gene id: 351160:RCI_RS03190
uniprot id: Q0W1V3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal Rpo3/eukaryotic RPB3 RNA polymerase subunit family.
messages: Binds 1 [3Fe-4S] cluster.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

351160:RCI RS13125
gene id: 351160:RCI_RS13125
uniprot id: Q0W7T5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 2 subfamily.
messages: Binds 3 Mg(2+) cations per subunit. The strongest magnesium site (Mg1) is bound to the beta- and gamma-phosphates of ATP and four water molecules complete its coordination sphere.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

351160:RCI RS09125
gene id: 351160:RCI_RS09125
uniprot id: Q0W5G2
names: Similarity
messages: Belongs to the UPF0147 family.

351160:RCI RS14235
gene id: 351160:RCI_RS14235
uniprot id: Q0W8F0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

351160:RCI RS05130
gene id: 351160:RCI_RS05130
uniprot id: Q0W303
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

351160:RCI RS03370
gene id: 351160:RCI_RS03370
uniprot id: Q0W1Y8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

351160:RCI RS05940
gene id: 351160:RCI_RS05940
uniprot id: Q0W3H1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

351160:RCI RS02675
gene id: 351160:RCI_RS02675
uniprot id: Q0W1J5
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family.
messages: Dimethylates a single guanine residue at position 26 of a number of tRNAs using S-adenosyl-L-methionine as donor of the methyl groups.

351160:RCI RS13930
gene id: 351160:RCI_RS13930
uniprot id: Q0W893
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

351160:RCI RS04250
gene id: 351160:RCI_RS04250
uniprot id: Q0W2H7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.
messages: Rubredoxin is a small nonheme, iron protein lacking acid-labile sulfide. Its single Fe, chelated to 4 Cys, functions as an electron acceptor and may also stabilize the conformation of the molecule.

351160:RCI RS11035
gene id: 351160:RCI_RS11035
uniprot id: Q0W6K7
names: Subcellular Location Annotation
messages: Cell membrane

351160:RCI RS06370
gene id: 351160:RCI_RS06370
uniprot id: Q0W3Q9
names: Subcellular Location Annotation
messages: Membrane

351160:RCI RS09185
gene id: 351160:RCI_RS09185
uniprot id: Q0W5H3
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL20 family.
messages: Part of the 50S ribosomal subunit. Binds 23S rRNA.

351160:RCI RS03205
gene id: 351160:RCI_RS03205
uniprot id: Q0W1V6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

351160:RCI RS12040
gene id: 351160:RCI_RS12040
uniprot id: Q0W766
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-insensitive subfamily.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force.

351160:RCI RS15525
gene id: 351160:RCI_RS15525
uniprot id: Q0W933
names: Function
names: Similarity
names: Subunit
messages: Belongs to the archaeal FAD synthase family.
messages: Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme.
messages: Homodimer.

351160:RCI RS15170
gene id: 351160:RCI_RS15170
uniprot id: Q0W954
names: Similarity
messages: Belongs to the DNA polymerase type-B family.

351160:RCI RS11810
gene id: 351160:RCI_RS11810
uniprot id: Q0W719
names: Function
names: Similarity
messages: Belongs to the archaeal 6-HMPDK family.
messages: Catalyzes the transfer of diphosphate from ATP to 6-hydroxymethyl-7,8-dihydropterin (6-HMD), leading to 6-hydroxymethyl-7,8-dihydropterin diphosphate (6-HMDP).

351160:RCI RS02350
gene id: 351160:RCI_RS02350
uniprot id: Q0W1C7
names: Cofactor
names: Similarity
messages: Belongs to the PdaD family.
messages: Binds 1 pyruvoyl group covalently per subunit.

351160:RCI RS01295
gene id: 351160:RCI_RS01295
uniprot id: Q0W0S5
names: Cofactor
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.

351160:RCI RS08785
gene id: 351160:RCI_RS08785
uniprot id: Q0W592
names: Subcellular Location Annotation
messages: Cytoplasm

351160:RCI RS11250
gene id: 351160:RCI_RS11250
uniprot id: Q0W6Q2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.

351160:RCI RS14300
gene id: 351160:RCI_RS14300
uniprot id: Q0W8G2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

351160:RCI RS03320
gene id: 351160:RCI_RS03320
uniprot id: Q0W1X8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L24e, part of which may contact the 16S rRNA in 2 intersubunit bridges.

351160:RCI RS05430
gene id: 351160:RCI_RS05430
uniprot id: Q0W363
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit.

351160:RCI RS08955
gene id: 351160:RCI_RS08955
uniprot id: Q0W5C7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the YjjX NTPase family.
messages: Binds 1 divalent metal cation per subunit; can use either Mg(2+) or Mn(2+).
messages: Homodimer.
messages: Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA/RNA precursor pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

351160:RCI RS14675
gene id: 351160:RCI_RS14675
uniprot id: Q0W8N3
names: Similarity
messages: Belongs to the archaeosine synthase type 1 family.

351160:RCI RS10900
gene id: 351160:RCI_RS10900
uniprot id: Q0W6H8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic/archaeal RNase P protein component 4 family.
messages: Binds 1 zinc ion per subunit.
messages: Consists of a catalytic RNA component and at least 4-5 protein subunits.
messages: Cytoplasm
messages: Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.

351160:RCI RS04605
gene id: 351160:RCI_RS04605
uniprot id: Q0W2P6
names: Subcellular Location Annotation
messages: Membrane