350688:CLOS RS13330
gene id: 350688:CLOS_RS13330
uniprot id: A8MJS0
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

350688:CLOS RS06335
gene id: 350688:CLOS_RS06335
uniprot id: A8MFA3
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Autoproteolytically processed. The inactive tetrameric zymogen termed p46 autoprocesses to a smaller form termed p41, which is active only during spore germination.
messages: Belongs to the peptidase A25 family.
messages: Homotetramer.
messages: Initiates the rapid degradation of small, acid-soluble proteins during spore germination.

350688:CLOS RS02675
gene id: 350688:CLOS_RS02675
uniprot id: A8MLG4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

350688:CLOS RS00420
gene id: 350688:CLOS_RS00420
uniprot id: A8MEG5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

350688:CLOS RS00245
gene id: 350688:CLOS_RS00245
uniprot id: A8MEE1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).

350688:CLOS RS05220
gene id: 350688:CLOS_RS05220
uniprot id: A8MG22
names: Subcellular Location Annotation
messages: Membrane

350688:CLOS RS03425
gene id: 350688:CLOS_RS03425
uniprot id: A8MM48
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZIP transporter (TC 2.A.5) family. ZupT subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mediates zinc uptake. May also transport other divalent cations.
messages: Membrane

350688:CLOS RS10505
gene id: 350688:CLOS_RS10505
uniprot id: A8MIB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protease PrsW family.
messages: Cell membrane
messages: Membrane

350688:CLOS RS02530
gene id: 350688:CLOS_RS02530
uniprot id: A8MLD5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

350688:CLOS RS07745
gene id: 350688:CLOS_RS07745
uniprot id: A8MHG1
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

350688:CLOS RS00450
gene id: 350688:CLOS_RS00450
uniprot id: A8MEH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetokinase family.
messages: Cytoplasm

350688:CLOS RS10695
gene id: 350688:CLOS_RS10695
uniprot id: A8MIF4
names: Similarity
messages: Belongs to the UPF0597 family.

350688:CLOS RS02795
gene id: 350688:CLOS_RS02795
uniprot id: A8MLI8
names: Caution
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

350688:CLOS RS13425
gene id: 350688:CLOS_RS13425
uniprot id: A8MJU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CotF family.
messages: Spore coat

350688:CLOS RS14940
gene id: 350688:CLOS_RS14940
uniprot id: A8MKN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

350688:CLOS RS06055
gene id: 350688:CLOS_RS06055
uniprot id: A8MF49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YejK family.
messages: nucleoid

350688:CLOS RS08830
gene id: 350688:CLOS_RS08830
uniprot id: A8MGN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

350688:CLOS RS04465
gene id: 350688:CLOS_RS04465
uniprot id: A8MET3
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.

350688:CLOS RS11000
gene id: 350688:CLOS_RS11000
uniprot id: A8MIL4
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

350688:CLOS RS01830
gene id: 350688:CLOS_RS01830
uniprot id: A8ML95
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

350688:CLOS RS02790
gene id: 350688:CLOS_RS02790
uniprot id: A8MLI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

350688:CLOS RS07840
gene id: 350688:CLOS_RS07840
uniprot id: A8MHH9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. PolC subfamily.
messages: Cytoplasm
messages: Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

350688:CLOS RS13715
gene id: 350688:CLOS_RS13715
uniprot id: A8MJZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

350688:CLOS RS00390
gene id: 350688:CLOS_RS00390
uniprot id: A8MEF9
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

350688:CLOS RS04475
gene id: 350688:CLOS_RS04475
uniprot id: A8MET5
names: Subcellular Location Annotation
messages: Membrane

350688:CLOS RS01410
gene id: 350688:CLOS_RS01410
uniprot id: A8ML11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

350688:CLOS RS11420
gene id: 350688:CLOS_RS11420
uniprot id: A8MIU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

350688:CLOS RS05030
gene id: 350688:CLOS_RS05030
uniprot id: A8MFY4
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-stimulated subfamily.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Requires K(+) for maximal activity.
messages: Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na(+) movement across the membrane.

350688:CLOS RS14185
gene id: 350688:CLOS_RS14185
uniprot id: A8MK92
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).

350688:CLOS RS00200
gene id: 350688:CLOS_RS00200
uniprot id: A8MED2
names: Similarity
messages: Belongs to the proline racemase family.

350688:CLOS RS03905
gene id: 350688:CLOS_RS03905
uniprot id: A8MEH7
names: Subcellular Location Annotation
messages: Membrane

350688:CLOS RS02780
gene id: 350688:CLOS_RS02780
uniprot id: A8MLI5
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

350688:CLOS RS09100
gene id: 350688:CLOS_RS09100
uniprot id: A8MHN2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

350688:CLOS RS05290
gene id: 350688:CLOS_RS05290
uniprot id: A8MG36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0394 family.
messages: Membrane

350688:CLOS RS05165
gene id: 350688:CLOS_RS05165
uniprot id: A8MG11
names: Activity Regulation
names: Function
names: Similarity
names: Subunit
messages: Activated by phosphorylation and inhibited by fructose 1,6-bisphosphate (FBP).
messages: Belongs to the FGGY kinase family.
messages: Homotetramer and homodimer (in equilibrium).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.

350688:CLOS RS01905
gene id: 350688:CLOS_RS01905
uniprot id: A8MLK9
names: Caution
names: Function
names: Similarity
messages: Belongs to the UbiX/PAD1 family.
messages: Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

350688:CLOS RS10880
gene id: 350688:CLOS_RS10880
uniprot id: A8MIJ1
names: Similarity
messages: Belongs to the peptidase U62 family.

350688:CLOS RS07575
gene id: 350688:CLOS_RS07575
uniprot id: A8MHC8
names: Similarity
messages: Belongs to the UPF0102 family.

350688:CLOS RS06330
gene id: 350688:CLOS_RS06330
uniprot id: A8MFA2
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

350688:CLOS RS02360
gene id: 350688:CLOS_RS02360
uniprot id: A8MLU8
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.

350688:CLOS RS07220
gene id: 350688:CLOS_RS07220
uniprot id: A8MH57
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Probably interacts with PlsX.

350688:CLOS RS02400
gene id: 350688:CLOS_RS02400
uniprot id: A8MLA9
names: Similarity
messages: Belongs to the ycf81 family.

350688:CLOS RS06550
gene id: 350688:CLOS_RS06550
uniprot id: A8MG85
names: Subcellular Location Annotation
messages: Membrane

350688:CLOS RS04485
gene id: 350688:CLOS_RS04485
uniprot id: A8MET7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

350688:CLOS RS05050
gene id: 350688:CLOS_RS05050
uniprot id: A8MFY8
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

350688:CLOS RS02120
gene id: 350688:CLOS_RS02120
uniprot id: A8MLQ2
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

350688:CLOS RS01745
gene id: 350688:CLOS_RS01745
uniprot id: A8ML78
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

350688:CLOS RS07795
gene id: 350688:CLOS_RS07795
uniprot id: A8MHH1
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by GTP. Inhibited by UTP.
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.

350688:CLOS RS02735
gene id: 350688:CLOS_RS02735
uniprot id: A8MLH6
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

350688:CLOS RS07380
gene id: 350688:CLOS_RS07380
uniprot id: A8MH89
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

350688:CLOS RS01575
gene id: 350688:CLOS_RS01575
uniprot id: A8ML45
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M20B family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Cleaves the N-terminal amino acid of tripeptides.
messages: Cytoplasm

350688:CLOS RS10995
gene id: 350688:CLOS_RS10995
uniprot id: A8MIL3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

350688:CLOS RS01465
gene id: 350688:CLOS_RS01465
uniprot id: A8ML22
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

350688:CLOS RS02315
gene id: 350688:CLOS_RS02315
uniprot id: A8MLU2
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

350688:CLOS RS06000
gene id: 350688:CLOS_RS06000
uniprot id: A8MF39
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

350688:CLOS RS10805
gene id: 350688:CLOS_RS10805
uniprot id: A8MIH6
names: Similarity
messages: Belongs to the SleB family.

350688:CLOS RS11745
gene id: 350688:CLOS_RS11745
uniprot id: A8MJ08
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

350688:CLOS RS02615
gene id: 350688:CLOS_RS02615
uniprot id: A8MLF2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

350688:CLOS RS03525
gene id: 350688:CLOS_RS03525
uniprot id: A8MM68
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the peroxiredoxin family. Tpx subfamily.
messages: Homodimer.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this atypical 2-Cys peroxiredoxin, C(R) is present in the same subunit to form an intramolecular disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

350688:CLOS RS01525
gene id: 350688:CLOS_RS01525
uniprot id: A8ML35
names: Similarity
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2.A.3.9) family.

350688:CLOS RS12965
gene id: 350688:CLOS_RS12965
uniprot id: A8MJJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

350688:CLOS RS13780
gene id: 350688:CLOS_RS13780
uniprot id: A8MK11
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

350688:CLOS RS03760
gene id: 350688:CLOS_RS03760
uniprot id: A8MMB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

350688:CLOS RS01040
gene id: 350688:CLOS_RS01040
uniprot id: A8MKT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

350688:CLOS RS06065
gene id: 350688:CLOS_RS06065
uniprot id: A8MF51
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

350688:CLOS RS02900
gene id: 350688:CLOS_RS02900
uniprot id: A8MLK6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

350688:CLOS RS03300
gene id: 350688:CLOS_RS03300
uniprot id: A8MM24
names: Subcellular Location Annotation
messages: Membrane

350688:CLOS RS01710
gene id: 350688:CLOS_RS01710
uniprot id: A8ML72
names: Function
names: Similarity
messages: Belongs to the methylglyoxal synthase family.
messages: Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.

350688:CLOS RS00645
gene id: 350688:CLOS_RS00645
uniprot id: A8MFP2
names: Similarity
messages: Belongs to the peptidase S51 family.

350688:CLOS RS08160
gene id: 350688:CLOS_RS08160
uniprot id: A8MFG7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ScpA family.
messages: Component of a cohesin-like complex composed of ScpA, ScpB and the Smc homodimer, in which ScpA and ScpB bind to the head domain of Smc. The presence of the three proteins is required for the association of the complex with DNA.
messages: Cytoplasm
messages: Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.

350688:CLOS RS08805
gene id: 350688:CLOS_RS08805
uniprot id: A8MGN2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

350688:CLOS RS13530
gene id: 350688:CLOS_RS13530
uniprot id: A8MJW1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

350688:CLOS RS08250
gene id: 350688:CLOS_RS08250
uniprot id: A8MFI5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

350688:CLOS RS07770
gene id: 350688:CLOS_RS07770
uniprot id: A8MHG6
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

350688:CLOS RS15020
gene id: 350688:CLOS_RS15020
uniprot id: A8MKQ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

350688:CLOS RS07520
gene id: 350688:CLOS_RS07520
uniprot id: A8MHB7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

350688:CLOS RS08780
gene id: 350688:CLOS_RS08780
uniprot id: A8MGM7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

350688:CLOS RS04915
gene id: 350688:CLOS_RS04915
uniprot id: A8MFW3
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

350688:CLOS RS15010
gene id: 350688:CLOS_RS15010
uniprot id: A8MKQ1
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

350688:CLOS RS07670
gene id: 350688:CLOS_RS07670
uniprot id: A8MHE7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

350688:CLOS RS13465
gene id: 350688:CLOS_RS13465
uniprot id: A8MJU8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

350688:CLOS RS02610
gene id: 350688:CLOS_RS02610
uniprot id: A8MLF1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

350688:CLOS RS12850
gene id: 350688:CLOS_RS12850
uniprot id: A8MJH5
names: Subcellular Location Annotation
messages: Cytoplasm

350688:CLOS RS09085
gene id: 350688:CLOS_RS09085
uniprot id: A8MHM9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

350688:CLOS RS01270
gene id: 350688:CLOS_RS01270
uniprot id: A8MKY3
names: Cofactor
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.
messages: Binds 3 [4Fe-4S] clusters per subunit.

350688:CLOS RS13415
gene id: 350688:CLOS_RS13415
uniprot id: A8MJT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

350688:CLOS RS05280
gene id: 350688:CLOS_RS05280
uniprot id: A8MG34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

350688:CLOS RS14095
gene id: 350688:CLOS_RS14095
uniprot id: A8MK74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

350688:CLOS RS12040
gene id: 350688:CLOS_RS12040
uniprot id: A8MJ65
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

350688:CLOS RS12430
gene id: 350688:CLOS_RS12430
uniprot id: A8MJE3
names: Similarity
messages: Belongs to the heat shock protein 70 family.

350688:CLOS RS14260
gene id: 350688:CLOS_RS14260
uniprot id: A8MKA7
names: Similarity
messages: Belongs to the SfsA family.

350688:CLOS RS03650
gene id: 350688:CLOS_RS03650
uniprot id: A8MM93
names: Similarity
messages: Belongs to the CAPAB/TerDEXZ family.

350688:CLOS RS11085
gene id: 350688:CLOS_RS11085
uniprot id: A8MIN1
names: Similarity
messages: Belongs to the formate--tetrahydrofolate ligase family.

350688:CLOS RS11805
gene id: 350688:CLOS_RS11805
uniprot id: A8MJ20
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 26 family. TagA/TarA subfamily.
messages: Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid.

350688:CLOS RS08840
gene id: 350688:CLOS_RS08840
uniprot id: A8MGP0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

350688:CLOS RS08045
gene id: 350688:CLOS_RS08045
uniprot id: A8MFE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

350688:CLOS RS07015
gene id: 350688:CLOS_RS07015
uniprot id: A8MH15
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm

350688:CLOS RS01385
gene id: 350688:CLOS_RS01385
uniprot id: A8ML06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family.
messages: Membrane

350688:CLOS RS01335
gene id: 350688:CLOS_RS01335
uniprot id: A8MKZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

350688:CLOS RS12110
gene id: 350688:CLOS_RS12110
uniprot id: A8MJ79
names: Similarity
messages: Belongs to the Mg-chelatase subunit H family.

350688:CLOS RS14645
gene id: 350688:CLOS_RS14645
uniprot id: A8MKI3
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

350688:CLOS RS12440
gene id: 350688:CLOS_RS12440
uniprot id: A8MJE5
names: Similarity
messages: Belongs to the EutP/PduV family.

350688:CLOS RS05985
gene id: 350688:CLOS_RS05985
uniprot id: A8MF36
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

350688:CLOS RS11410
gene id: 350688:CLOS_RS11410
uniprot id: A8MIU7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

350688:CLOS RS06020
gene id: 350688:CLOS_RS06020
uniprot id: A8MF42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

350688:CLOS RS13005
gene id: 350688:CLOS_RS13005
uniprot id: A8MJK5
names: Similarity
messages: Belongs to the dihydropyrimidine dehydrogenase family.

350688:CLOS RS07560
gene id: 350688:CLOS_RS07560
uniprot id: A8MHC5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

350688:CLOS RS13225
gene id: 350688:CLOS_RS13225
uniprot id: A8MJQ0
names: Subcellular Location Annotation
messages: Membrane

350688:CLOS RS01775
gene id: 350688:CLOS_RS01775
uniprot id: A8ML84
names: Similarity
messages: Belongs to the PHP hydrolase family. HisK subfamily.

350688:CLOS RS14090
gene id: 350688:CLOS_RS14090
uniprot id: A8MK73
names: Subcellular Location Annotation
messages: Membrane

350688:CLOS RS06400
gene id: 350688:CLOS_RS06400
uniprot id: A8MG57
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

350688:CLOS RS01345
gene id: 350688:CLOS_RS01345
uniprot id: A8MKZ8
names: Function
names: Similarity
messages: Belongs to the glutamate--cysteine ligase type 2 family. EgtA subfamily.
messages: Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC).

350688:CLOS RS13210
gene id: 350688:CLOS_RS13210
uniprot id: A8MJP7
names: Subcellular Location Annotation
messages: Membrane

350688:CLOS RS10480
gene id: 350688:CLOS_RS10480
uniprot id: A8MIB3
names: Similarity
names: Subunit
messages: Belongs to the glutaminase family.
messages: Homotetramer.

350688:CLOS RS02495
gene id: 350688:CLOS_RS02495
uniprot id: A8MLC8
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

350688:CLOS RS08865
gene id: 350688:CLOS_RS08865
uniprot id: A8MHI6
names: Similarity
messages: Belongs to the peptidase S16 family.

350688:CLOS RS09045
gene id: 350688:CLOS_RS09045
uniprot id: A8MHM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Membrane

350688:CLOS RS05365
gene id: 350688:CLOS_RS05365
uniprot id: A8MGP3
names: Cofactor
names: Function
messages: Binds 2 [4Fe-4S] clusters. In this family the first cluster has a non-standard and varying [4Fe-4S] binding motif CX(2)CX(2)CX(4-5)CP.
messages: Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.

350688:CLOS RS07550
gene id: 350688:CLOS_RS07550
uniprot id: A8MHC3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

350688:CLOS RS02575
gene id: 350688:CLOS_RS02575
uniprot id: A8MLE4
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

350688:CLOS RS04755
gene id: 350688:CLOS_RS04755
uniprot id: A8MEZ0
names: Subcellular Location Annotation
messages: Membrane

350688:CLOS RS02625
gene id: 350688:CLOS_RS02625
uniprot id: A8MLF4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

350688:CLOS RS03315
gene id: 350688:CLOS_RS03315
uniprot id: A8MM27
names: Similarity
messages: Belongs to the OsmC/Ohr family.

350688:CLOS RS08955
gene id: 350688:CLOS_RS08955
uniprot id: A8MHK3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein L14 (rplN).

350688:CLOS RS07600
gene id: 350688:CLOS_RS07600
uniprot id: A8MHD3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

350688:CLOS RS11525
gene id: 350688:CLOS_RS11525
uniprot id: A8MIW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

350688:CLOS RS00415
gene id: 350688:CLOS_RS00415
uniprot id: A8MEG4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

350688:CLOS RS14265
gene id: 350688:CLOS_RS14265
uniprot id: A8MKA8
names: Similarity
messages: Belongs to the UPF0178 family.

350688:CLOS RS00115
gene id: 350688:CLOS_RS00115
uniprot id: A8MEB7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

350688:CLOS RS10685
gene id: 350688:CLOS_RS10685
uniprot id: A8MIF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

350688:CLOS RS15040
gene id: 350688:CLOS_RS15040
uniprot id: A8MKQ7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

350688:CLOS RS02170
gene id: 350688:CLOS_RS02170
uniprot id: A8MLR3
names: Similarity
messages: Belongs to the radical SAM superfamily. KamA family.

350688:CLOS RS05380
gene id: 350688:CLOS_RS05380
uniprot id: A8MGP5
names: Subcellular Location Annotation
messages: Membrane

350688:CLOS RS02500
gene id: 350688:CLOS_RS02500
uniprot id: A8MLC9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

350688:CLOS RS00255
gene id: 350688:CLOS_RS00255
uniprot id: A8MEE3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

350688:CLOS RS14840
gene id: 350688:CLOS_RS14840
uniprot id: A8MKM1
names: Subcellular Location Annotation
messages: Membrane

350688:CLOS RS04690
gene id: 350688:CLOS_RS04690
uniprot id: A8MEX7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
messages: Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
messages: Homodimer.

350688:CLOS RS16120
gene id: 350688:CLOS_RS16120
uniprot id: A8MK40
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PrsA family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins.

350688:CLOS RS10915
gene id: 350688:CLOS_RS10915
uniprot id: A8MIJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

350688:CLOS RS04985
gene id: 350688:CLOS_RS04985
uniprot id: A8MFX5
names: Subcellular Location Annotation
messages: Membrane

350688:CLOS RS08985
gene id: 350688:CLOS_RS08985
uniprot id: A8MHK9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

350688:CLOS RS07300
gene id: 350688:CLOS_RS07300
uniprot id: A8MH73
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

350688:CLOS RS10850
gene id: 350688:CLOS_RS10850
uniprot id: A8MII5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family.
messages: Cell membrane
messages: Membrane

350688:CLOS RS13290
gene id: 350688:CLOS_RS13290
uniprot id: A8MJR3
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

350688:CLOS RS02845
gene id: 350688:CLOS_RS02845
uniprot id: A8MLJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

350688:CLOS RS14205
gene id: 350688:CLOS_RS14205
uniprot id: A8MK96
names: Similarity
messages: Belongs to the SAICAR synthetase family.

350688:CLOS RS13670
gene id: 350688:CLOS_RS13670
uniprot id: A8MJY9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

350688:CLOS RS07500
gene id: 350688:CLOS_RS07500
uniprot id: A8MHB3
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

350688:CLOS RS02680
gene id: 350688:CLOS_RS02680
uniprot id: A8MLG5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

350688:CLOS RS14170
gene id: 350688:CLOS_RS14170
uniprot id: A8MK89
names: Cofactor
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Binds 1 FAD per subunit.
messages: Binds 1 FMN covalently per subunit.

350688:CLOS RS12130
gene id: 350688:CLOS_RS12130
uniprot id: A8MJ83
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type II sub-subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The autoendoproteolytic cleavage occurs by a canonical serine protease mechanism, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. During this reaction, the Ser that is part of the protease active site of the proenzyme becomes the pyruvoyl prosthetic group, which constitutes an essential element of the active site of the mature decarboxylase.

350688:CLOS RS12100
gene id: 350688:CLOS_RS12100
uniprot id: A8MJ77
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family.

350688:CLOS RS08750
gene id: 350688:CLOS_RS08750
uniprot id: A8MGM1
names: Similarity
messages: Belongs to the peptidase M18 family.

350688:CLOS RS07895
gene id: 350688:CLOS_RS07895
uniprot id: A8MFB4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

350688:CLOS RS04990
gene id: 350688:CLOS_RS04990
uniprot id: A8MFX6
names: Similarity
messages: Belongs to the sigma-54 factor family.

350688:CLOS RS00240
gene id: 350688:CLOS_RS00240
uniprot id: A8MEE0
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

350688:CLOS RS10725
gene id: 350688:CLOS_RS10725
uniprot id: A8MIG0
names: Caution
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

350688:CLOS RS09035
gene id: 350688:CLOS_RS09035
uniprot id: A8MHL9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MinC family.
messages: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.
messages: Interacts with MinD and FtsZ.

350688:CLOS RS01945
gene id: 350688:CLOS_RS01945
uniprot id: A8MLL7
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.

350688:CLOS RS07695
gene id: 350688:CLOS_RS07695
uniprot id: A8MHF1
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

350688:CLOS RS06025
gene id: 350688:CLOS_RS06025
uniprot id: A8MF43
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M3B family.
messages: Binds 1 zinc ion.
messages: Has oligopeptidase activity and degrades a variety of small bioactive peptides.

350688:CLOS RS09040
gene id: 350688:CLOS_RS09040
uniprot id: A8MHM0
names: Similarity
messages: Belongs to the transpeptidase family.

350688:CLOS RS11430
gene id: 350688:CLOS_RS11430
uniprot id: A8MIV1
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

350688:CLOS RS08770
gene id: 350688:CLOS_RS08770
uniprot id: A8MGM5
names: Similarity
messages: Belongs to the UPF0751 family.

350688:CLOS RS07730
gene id: 350688:CLOS_RS07730
uniprot id: A8MHF8
names: Function
names: Similarity
messages: Belongs to the GTP-binding SRP family.
messages: Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum.

350688:CLOS RS02710
gene id: 350688:CLOS_RS02710
uniprot id: A8MLH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane

350688:CLOS RS03505
gene id: 350688:CLOS_RS03505
uniprot id: A8MM64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0053 family.
messages: Membrane

350688:CLOS RS14060
gene id: 350688:CLOS_RS14060
uniprot id: A8MK67
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

350688:CLOS RS00030
gene id: 350688:CLOS_RS00030
uniprot id: A8MEA3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

350688:CLOS RS00810
gene id: 350688:CLOS_RS00810
uniprot id: A8MFS3
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

350688:CLOS RS06990
gene id: 350688:CLOS_RS06990
uniprot id: A8MH11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

350688:CLOS RS08555
gene id: 350688:CLOS_RS08555
uniprot id: A8MGI2
names: Similarity
messages: Belongs to the UPF0297 family.

350688:CLOS RS14315
gene id: 350688:CLOS_RS14315
uniprot id: A8MKB8
names: Similarity
messages: Belongs to the GerABKC lipoprotein family.

350688:CLOS RS03360
gene id: 350688:CLOS_RS03360
uniprot id: A8MM36
names: Subcellular Location Annotation
messages: Membrane

350688:CLOS RS12375
gene id: 350688:CLOS_RS12375
uniprot id: A8MJD2
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

350688:CLOS RS05785
gene id: 350688:CLOS_RS05785
uniprot id: A8MGX2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

350688:CLOS RS02070
gene id: 350688:CLOS_RS02070
uniprot id: A8MLP2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

350688:CLOS RS14655
gene id: 350688:CLOS_RS14655
uniprot id: A8MKI5
names: Similarity
messages: Belongs to the peptidase S8 family.

350688:CLOS RS16140
gene id: 350688:CLOS_RS16140
uniprot id: A8MKS3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

350688:CLOS RS09050
gene id: 350688:CLOS_RS09050
uniprot id: A8MHM2
names: Function
names: Similarity
messages: Belongs to the MreC family.
messages: Involved in formation and maintenance of cell shape.

350688:CLOS RS07680
gene id: 350688:CLOS_RS07680
uniprot id: A8MHE9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

350688:CLOS RS00550
gene id: 350688:CLOS_RS00550
uniprot id: A8MFM2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

350688:CLOS RS04685
gene id: 350688:CLOS_RS04685
uniprot id: A8MEX6
names: Similarity
messages: Belongs to the peptidase S16 family.

350688:CLOS RS08050
gene id: 350688:CLOS_RS08050
uniprot id: A8MFE5
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis.
messages: Cytoplasm

350688:CLOS RS08560
gene id: 350688:CLOS_RS08560
uniprot id: A8MGI3
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

350688:CLOS RS03160
gene id: 350688:CLOS_RS03160
uniprot id: A8MLZ7
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

350688:CLOS RS13410
gene id: 350688:CLOS_RS13410
uniprot id: A8MJT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

350688:CLOS RS00205
gene id: 350688:CLOS_RS00205
uniprot id: A8MED3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

350688:CLOS RS03355
gene id: 350688:CLOS_RS03355
uniprot id: A8MM35
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

350688:CLOS RS03500
gene id: 350688:CLOS_RS03500
uniprot id: A8MM63
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HCP family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Binds 1 hybrid [4Fe-2O-2S] cluster.
messages: Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
messages: Cytoplasm

350688:CLOS RS05100
gene id: 350688:CLOS_RS05100
uniprot id: A8MFZ8
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

350688:CLOS RS04275
gene id: 350688:CLOS_RS04275
uniprot id: A8MEP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

350688:CLOS RS07535
gene id: 350688:CLOS_RS07535
uniprot id: A8MHC0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

350688:CLOS RS14080
gene id: 350688:CLOS_RS14080
uniprot id: A8MK71
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

350688:CLOS RS08405
gene id: 350688:CLOS_RS08405
uniprot id: A8MGF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

350688:CLOS RS04100
gene id: 350688:CLOS_RS04100
uniprot id: A8MEL4
names: Similarity
messages: Belongs to the EutP/PduV family.

350688:CLOS RS03225
gene id: 350688:CLOS_RS03225
uniprot id: A8MM09
names: Subcellular Location Annotation
messages: Membrane

350688:CLOS RS10630
gene id: 350688:CLOS_RS10630
uniprot id: A8MIE3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane
messages: This protein catalyzes the committed step to the synthesis of the acidic phospholipids.

350688:CLOS RS03415
gene id: 350688:CLOS_RS03415
uniprot id: A8MM46
names: Similarity
messages: Belongs to the thioredoxin family.

350688:CLOS RS06465
gene id: 350688:CLOS_RS06465
uniprot id: A8MG70
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

350688:CLOS RS06010
gene id: 350688:CLOS_RS06010
uniprot id: A8MF41
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

350688:CLOS RS01955
gene id: 350688:CLOS_RS01955
uniprot id: A8MLL9
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L-homocysteine, respectively. Is also able to deaminate adenosine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

350688:CLOS RS05575
gene id: 350688:CLOS_RS05575
uniprot id: A8MGT2
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

350688:CLOS RS11235
gene id: 350688:CLOS_RS11235
uniprot id: A8MIR1
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

350688:CLOS RS10625
gene id: 350688:CLOS_RS10625
uniprot id: A8MIE2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

350688:CLOS RS07540
gene id: 350688:CLOS_RS07540
uniprot id: A8MHC1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

350688:CLOS RS07570
gene id: 350688:CLOS_RS07570
uniprot id: A8MHC7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

350688:CLOS RS02725
gene id: 350688:CLOS_RS02725
uniprot id: A8MLH4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

350688:CLOS RS10980
gene id: 350688:CLOS_RS10980
uniprot id: A8MIL0
names: Function
names: Similarity
names: Subunit
messages: Catalyzes the ATP-dependent polymerization of arginine and aspartate to multi-L-arginyl-poly-L-aspartic acid (cyanophycin; a water-insoluble reserve polymer).
messages: Homodimer.
messages: In the C-terminal section; belongs to the MurCDEF family.

350688:CLOS RS14435
gene id: 350688:CLOS_RS14435
uniprot id: A8MKE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

350688:CLOS RS03255
gene id: 350688:CLOS_RS03255
uniprot id: A8MM15
names: Similarity
messages: Belongs to the AAE transporter (TC 2.A.81) family.

350688:CLOS RS08795
gene id: 350688:CLOS_RS08795
uniprot id: A8MGN0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

350688:CLOS RS06220
gene id: 350688:CLOS_RS06220
uniprot id: A8MF81
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

350688:CLOS RS00260
gene id: 350688:CLOS_RS00260
uniprot id: A8MEE4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

350688:CLOS RS08995
gene id: 350688:CLOS_RS08995
uniprot id: A8MHL1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

350688:CLOS RS09060
gene id: 350688:CLOS_RS09060
uniprot id: A8MHM4
names: Similarity
messages: Belongs to the UPF0758 family.

350688:CLOS RS08170
gene id: 350688:CLOS_RS08170
uniprot id: A8MFG9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Catalyzes phosphorolysis of the pyrimidine nucleosides uridine, thymidine and 2'-deoxyuridine with the formation of the corresponding pyrimidine base and ribose-1-phosphate.
messages: Homodimer.

350688:CLOS RS08790
gene id: 350688:CLOS_RS08790
uniprot id: A8MGM9
names: Similarity
messages: Belongs to the metallo-beta-lactamase superfamily. Class-B beta-lactamase family.

350688:CLOS RS11690
gene id: 350688:CLOS_RS11690
uniprot id: A8MIZ8
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

350688:CLOS RS01380
gene id: 350688:CLOS_RS01380
uniprot id: A8ML05
names: Similarity
messages: Belongs to the EamA transporter family.

350688:CLOS RS06985
gene id: 350688:CLOS_RS06985
uniprot id: A8MH10
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

350688:CLOS RS09300
gene id: 350688:CLOS_RS09300
uniprot id: A8MHS2
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.

350688:CLOS RS07340
gene id: 350688:CLOS_RS07340
uniprot id: A8MH81
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

350688:CLOS RS01240
gene id: 350688:CLOS_RS01240
uniprot id: A8MKX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. AsnA subfamily.
messages: Cytoplasm

350688:CLOS RS07660
gene id: 350688:CLOS_RS07660
uniprot id: A8MHE5
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

350688:CLOS RS14680
gene id: 350688:CLOS_RS14680
uniprot id: A8MKJ0
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

350688:CLOS RS11195
gene id: 350688:CLOS_RS11195
uniprot id: A8MIQ3
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

350688:CLOS RS04310
gene id: 350688:CLOS_RS04310
uniprot id: A8MEQ2
names: Similarity
messages: Belongs to the Dps family.

350688:CLOS RS00110
gene id: 350688:CLOS_RS00110
uniprot id: A8MEB6
names: Similarity
messages: Belongs to the YciI family.

350688:CLOS RS10555
gene id: 350688:CLOS_RS10555
uniprot id: A8MIC8
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

350688:CLOS RS10885
gene id: 350688:CLOS_RS10885
uniprot id: A8MIJ2
names: Similarity
messages: Belongs to the peptidase U62 family.

350688:CLOS RS03465
gene id: 350688:CLOS_RS03465
uniprot id: A8MM56
names: Similarity
messages: Belongs to the peptidase M29 family.

350688:CLOS RS07095
gene id: 350688:CLOS_RS07095
uniprot id: A8MH32
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

350688:CLOS RS05630
gene id: 350688:CLOS_RS05630
uniprot id: A8MGU2
names: Function
messages: Mediates the mercuric-dependent induction of mercury resistance operon. In the absence of mercury MerR represses transcription by binding tightly to the mer operator region; when mercury is present the dimeric complex binds a single ion and becomes a potent transcriptional activator, while remaining bound to the mer site.

350688:CLOS RS08740
gene id: 350688:CLOS_RS08740
uniprot id: A8MGL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThrE exporter (TC 2.A.79) family.
messages: Membrane

350688:CLOS RS00735
gene id: 350688:CLOS_RS00735
uniprot id: A8MFQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Cell membrane
messages: Membrane

350688:CLOS RS08980
gene id: 350688:CLOS_RS08980
uniprot id: A8MHK8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

350688:CLOS RS13790
gene id: 350688:CLOS_RS13790
uniprot id: A8MK13
names: Subcellular Location Annotation
messages: Membrane

350688:CLOS RS10785
gene id: 350688:CLOS_RS10785
uniprot id: A8MIH2
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

350688:CLOS RS11330
gene id: 350688:CLOS_RS11330
uniprot id: A8MIT0
names: Subcellular Location Annotation
messages: Cytoplasm

350688:CLOS RS03790
gene id: 350688:CLOS_RS03790
uniprot id: A8MMC1
names: Subcellular Location Annotation
messages: Membrane

350688:CLOS RS11490
gene id: 350688:CLOS_RS11490
uniprot id: A8MIW2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.

350688:CLOS RS11915
gene id: 350688:CLOS_RS11915
uniprot id: A8MJ41
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. AddA subfamily.
messages: Heterodimer of AddA and AddB/RexB.
messages: The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation; this subunit has the helicase and 3' -> 5' nuclease activities.

350688:CLOS RS13150
gene id: 350688:CLOS_RS13150
uniprot id: A8MJN5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: May bind 1 zinc ion per subunit.
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

350688:CLOS RS02505
gene id: 350688:CLOS_RS02505
uniprot id: A8MLD0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

350688:CLOS RS11400
gene id: 350688:CLOS_RS11400
uniprot id: A8MIU5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PyrK family.
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Heterotetramer of 2 PyrK and 2 PyrD type B subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+).

350688:CLOS RS10225
gene id: 350688:CLOS_RS10225
uniprot id: A8MI69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0394 family.
messages: Membrane

350688:CLOS RS02715
gene id: 350688:CLOS_RS02715
uniprot id: A8MLH2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex.
messages: Belongs to the ABC transporter superfamily. Energy-coupling factor EcfA family.
messages: Cell membrane
messages: Forms a stable energy-coupling factor (ECF) transporter complex composed of 2 membrane-embedded substrate-binding proteins (S component), 2 ATP-binding proteins (A component) and 2 transmembrane proteins (T component).
messages: Membrane

350688:CLOS RS01595
gene id: 350688:CLOS_RS01595
uniprot id: A8ML49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

350688:CLOS RS00095
gene id: 350688:CLOS_RS00095
uniprot id: A8MEB3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.

350688:CLOS RS09205
gene id: 350688:CLOS_RS09205
uniprot id: A8MHQ3
names: Function
names: Similarity
messages: Belongs to the anti-sigma-factor family.
messages: Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.

350688:CLOS RS10515
gene id: 350688:CLOS_RS10515
uniprot id: A8MIC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

350688:CLOS RS05590
gene id: 350688:CLOS_RS05590
uniprot id: A8MGT4
names: Subcellular Location Annotation
messages: Membrane

350688:CLOS RS03470
gene id: 350688:CLOS_RS03470
uniprot id: A8MM57
names: Similarity
messages: Belongs to the serine/threonine dehydratase family. DsdA subfamily.

350688:CLOS RS06115
gene id: 350688:CLOS_RS06115
uniprot id: A8MF61
names: Similarity
messages: Belongs to the diacylglycerol/lipid kinase family.

350688:CLOS RS02110
gene id: 350688:CLOS_RS02110
uniprot id: A8MLQ0
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

350688:CLOS RS04830
gene id: 350688:CLOS_RS04830
uniprot id: A8MF05
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

350688:CLOS RS10330
gene id: 350688:CLOS_RS10330
uniprot id: A8MI90
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

350688:CLOS RS11180
gene id: 350688:CLOS_RS11180
uniprot id: A8MIQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

350688:CLOS RS11985
gene id: 350688:CLOS_RS11985
uniprot id: A8MJ54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Membrane

350688:CLOS RS03070
gene id: 350688:CLOS_RS03070
uniprot id: A8MLY0
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homotetramer.

350688:CLOS RS07120
gene id: 350688:CLOS_RS07120
uniprot id: A8MH37
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

350688:CLOS RS13720
gene id: 350688:CLOS_RS13720
uniprot id: A8MJZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

350688:CLOS RS00140
gene id: 350688:CLOS_RS00140
uniprot id: A8MEC1
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

350688:CLOS RS11140
gene id: 350688:CLOS_RS11140
uniprot id: A8MIP2
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

350688:CLOS RS13575
gene id: 350688:CLOS_RS13575
uniprot id: A8MJX0
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

350688:CLOS RS03965
gene id: 350688:CLOS_RS03965
uniprot id: A8MEI9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

350688:CLOS RS00915
gene id: 350688:CLOS_RS00915
uniprot id: A8MFU2
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

350688:CLOS RS13085
gene id: 350688:CLOS_RS13085
uniprot id: A8MJM2
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

350688:CLOS RS03455
gene id: 350688:CLOS_RS03455
uniprot id: A8MM54
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell membrane
messages: Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation.

350688:CLOS RS12560
gene id: 350688:CLOS_RS12560
uniprot id: A8MJG9
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

350688:CLOS RS06900
gene id: 350688:CLOS_RS06900
uniprot id: A8MGZ4
names: Subcellular Location Annotation
messages: Membrane

350688:CLOS RS07330
gene id: 350688:CLOS_RS07330
uniprot id: A8MH79
names: Similarity
messages: Belongs to the RemA family.

350688:CLOS RS02380
gene id: 350688:CLOS_RS02380
uniprot id: A8MLV2
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

350688:CLOS RS04780
gene id: 350688:CLOS_RS04780
uniprot id: A8MEZ5
names: Cofactor
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.

350688:CLOS RS15015
gene id: 350688:CLOS_RS15015
uniprot id: A8MKQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

350688:CLOS RS04425
gene id: 350688:CLOS_RS04425
uniprot id: A8MES5
names: Similarity
messages: Belongs to the EamA transporter family.

350688:CLOS RS01700
gene id: 350688:CLOS_RS01700
uniprot id: A8ML70
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

350688:CLOS RS07335
gene id: 350688:CLOS_RS07335
uniprot id: A8MH80
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

350688:CLOS RS13310
gene id: 350688:CLOS_RS13310
uniprot id: A8MJR7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

350688:CLOS RS08775
gene id: 350688:CLOS_RS08775
uniprot id: A8MGM6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

350688:CLOS RS08940
gene id: 350688:CLOS_RS08940
uniprot id: A8MHK0
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

350688:CLOS RS11260
gene id: 350688:CLOS_RS11260
uniprot id: A8MIR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

350688:CLOS RS08260
gene id: 350688:CLOS_RS08260
uniprot id: A8MFI7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

350688:CLOS RS07450
gene id: 350688:CLOS_RS07450
uniprot id: A8MHA3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TmcAL family.
messages: Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates. First activates an acetate ion to form acetyladenylate (Ac-AMP) and then transfers the acetyl group to tRNA to form ac(4)C34.
messages: Cytoplasm

350688:CLOS RS02620
gene id: 350688:CLOS_RS02620
uniprot id: A8MLF3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

350688:CLOS RS15085
gene id: 350688:CLOS_RS15085
uniprot id: A8MKR6
names: Similarity
messages: Belongs to the ParB family.

350688:CLOS RS02800
gene id: 350688:CLOS_RS02800
uniprot id: A8MLI9
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

350688:CLOS RS06355
gene id: 350688:CLOS_RS06355
uniprot id: A8MG48
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

350688:CLOS RS13115
gene id: 350688:CLOS_RS13115
uniprot id: A8MJM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

350688:CLOS RS02210
gene id: 350688:CLOS_RS02210
uniprot id: A8MLS1
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

350688:CLOS RS07505
gene id: 350688:CLOS_RS07505
uniprot id: A8MHB4
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

350688:CLOS RS07710
gene id: 350688:CLOS_RS07710
uniprot id: A8MHF4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

350688:CLOS RS09290
gene id: 350688:CLOS_RS09290
uniprot id: A8MHS0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

350688:CLOS RS04105
gene id: 350688:CLOS_RS04105
uniprot id: A8MEL5
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

350688:CLOS RS05885
gene id: 350688:CLOS_RS05885
uniprot id: A8MF17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Membrane

350688:CLOS RS10865
gene id: 350688:CLOS_RS10865
uniprot id: A8MII8
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

350688:CLOS RS06110
gene id: 350688:CLOS_RS06110
uniprot id: A8MF60
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

350688:CLOS RS13375
gene id: 350688:CLOS_RS13375
uniprot id: A8MJT0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

350688:CLOS RS05170
gene id: 350688:CLOS_RS05170
uniprot id: A8MG12
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Monomer.

350688:CLOS RS01190
gene id: 350688:CLOS_RS01190
uniprot id: A8MKW8
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily.

350688:CLOS RS12470
gene id: 350688:CLOS_RS12470
uniprot id: A8MJF1
names: Similarity
messages: Belongs to the bacterial microcompartments protein family.

350688:CLOS RS14710
gene id: 350688:CLOS_RS14710
uniprot id: A8MKJ6
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

350688:CLOS RS04295
gene id: 350688:CLOS_RS04295
uniprot id: A8MEP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

350688:CLOS RS05305
gene id: 350688:CLOS_RS05305
uniprot id: A8MG39
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

350688:CLOS RS02755
gene id: 350688:CLOS_RS02755
uniprot id: A8MLI0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

350688:CLOS RS06965
gene id: 350688:CLOS_RS06965
uniprot id: A8MH06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

350688:CLOS RS12150
gene id: 350688:CLOS_RS12150
uniprot id: A8MJ87
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-I 3-dehydroquinase family.
messages: Homodimer.
messages: Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate.

350688:CLOS RS01020
gene id: 350688:CLOS_RS01020
uniprot id: A8MKT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

350688:CLOS RS06600
gene id: 350688:CLOS_RS06600
uniprot id: A8MG95
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

350688:CLOS RS13065
gene id: 350688:CLOS_RS13065
uniprot id: A8MJL8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acetylates the N-terminal alanine of ribosomal protein S18.
messages: Belongs to the acetyltransferase family. RimI subfamily.
messages: Cytoplasm

350688:CLOS RS00085
gene id: 350688:CLOS_RS00085
uniprot id: A8MEB1
names: Subcellular Location Annotation
messages: Membrane

350688:CLOS RS01555
gene id: 350688:CLOS_RS01555
uniprot id: A8ML41
names: Similarity
messages: Belongs to the CdaR family.

350688:CLOS RS14195
gene id: 350688:CLOS_RS14195
uniprot id: A8MK94
names: Similarity
messages: Belongs to the ThiD family.

350688:CLOS RS11735
gene id: 350688:CLOS_RS11735
uniprot id: A8MJ06
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

350688:CLOS RS01390
gene id: 350688:CLOS_RS01390
uniprot id: A8ML07
names: Subcellular Location Annotation
messages: Membrane

350688:CLOS RS02330
gene id: 350688:CLOS_RS02330
uniprot id: A8MLU5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

350688:CLOS RS11990
gene id: 350688:CLOS_RS11990
uniprot id: A8MJ55
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

350688:CLOS RS04980
gene id: 350688:CLOS_RS04980
uniprot id: A8MFX4
names: Subcellular Location Annotation
messages: Membrane

350688:CLOS RS07585
gene id: 350688:CLOS_RS07585
uniprot id: A8MHD0
names: Similarity
messages: Belongs to the DprA/Smf family.

350688:CLOS RS11395
gene id: 350688:CLOS_RS11395
uniprot id: A8MIU4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with NAD(+) as electron acceptor.
messages: Cytoplasm
messages: Heterotetramer of 2 PyrK and 2 PyrD type B subunits.

350688:CLOS RS10935
gene id: 350688:CLOS_RS10935
uniprot id: A8MIK2
names: Similarity
messages: Belongs to the glutamine synthetase family.

350688:CLOS RS02420
gene id: 350688:CLOS_RS02420
uniprot id: A8MLB3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.
messages: Cytoplasm
messages: Homodimer.

350688:CLOS RS09055
gene id: 350688:CLOS_RS09055
uniprot id: A8MHM3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

350688:CLOS RS07905
gene id: 350688:CLOS_RS07905
uniprot id: A8MFB6
names: Similarity
messages: Belongs to the peptidase M16 family.

350688:CLOS RS06205
gene id: 350688:CLOS_RS06205
uniprot id: A8MF79
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

350688:CLOS RS10720
gene id: 350688:CLOS_RS10720
uniprot id: A8MIF9
names: Similarity
messages: Belongs to the pirin family.

350688:CLOS RS04920
gene id: 350688:CLOS_RS04920
uniprot id: A8MFW4
names: Similarity
messages: Belongs to the thioredoxin family.

350688:CLOS RS00690
gene id: 350688:CLOS_RS00690
uniprot id: A8MFP9
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

350688:CLOS RS06370
gene id: 350688:CLOS_RS06370
uniprot id: A8MG51
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

350688:CLOS RS13665
gene id: 350688:CLOS_RS13665
uniprot id: A8MJY8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.

350688:CLOS RS07130
gene id: 350688:CLOS_RS07130
uniprot id: A8MH39
names: Similarity
messages: Belongs to the UPF0749 family.

350688:CLOS RS13835
gene id: 350688:CLOS_RS13835
uniprot id: A8MK22
names: Function
names: Similarity
messages: Belongs to the 'phage' integrase family.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

350688:CLOS RS11380
gene id: 350688:CLOS_RS11380
uniprot id: A8MIU1
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

350688:CLOS RS02085
gene id: 350688:CLOS_RS02085
uniprot id: A8MLP5
names: Similarity
messages: Belongs to the EamA transporter family.

350688:CLOS RS03330
gene id: 350688:CLOS_RS03330
uniprot id: A8MM30
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

350688:CLOS RS06045
gene id: 350688:CLOS_RS06045
uniprot id: A8MF47
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

350688:CLOS RS00050
gene id: 350688:CLOS_RS00050
uniprot id: A8MEA7
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

350688:CLOS RS02560
gene id: 350688:CLOS_RS02560
uniprot id: A8MLE1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

350688:CLOS RS00340
gene id: 350688:CLOS_RS00340
uniprot id: A8MEF1
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

350688:CLOS RS09080
gene id: 350688:CLOS_RS09080
uniprot id: A8MHM8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.
messages: Binds 3 [4Fe-4S] clusters.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

350688:CLOS RS02275
gene id: 350688:CLOS_RS02275
uniprot id: A8MLT4
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

350688:CLOS RS13025
gene id: 350688:CLOS_RS13025
uniprot id: A8MJK9
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

350688:CLOS RS15070
gene id: 350688:CLOS_RS15070
uniprot id: A8MKR3
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.

350688:CLOS RS13945
gene id: 350688:CLOS_RS13945
uniprot id: A8MK44
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

350688:CLOS RS13535
gene id: 350688:CLOS_RS13535
uniprot id: A8MJW2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

350688:CLOS RS02555
gene id: 350688:CLOS_RS02555
uniprot id: A8MLE0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

350688:CLOS RS01845
gene id: 350688:CLOS_RS01845
uniprot id: A8ML98
names: Similarity
messages: Belongs to the EamA transporter family.

350688:CLOS RS01440
gene id: 350688:CLOS_RS01440
uniprot id: A8ML17
names: Similarity
messages: Belongs to the 5'(3')-deoxyribonucleotidase family.

350688:CLOS RS15110
gene id: 350688:CLOS_RS15110
uniprot id: A8MKS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OXA1/ALB3/YidC family.
messages: Membrane

350688:CLOS RS04725
gene id: 350688:CLOS_RS04725
uniprot id: A8MEY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

350688:CLOS RS01290
gene id: 350688:CLOS_RS01290
uniprot id: A8MKY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

350688:CLOS RS13295
gene id: 350688:CLOS_RS13295
uniprot id: A8MJR4
names: Similarity
messages: Belongs to the polysaccharide synthase family.

350688:CLOS RS10465
gene id: 350688:CLOS_RS10465
uniprot id: A8MIB0
names: Subcellular Location Annotation
messages: Cytoplasm

350688:CLOS RS01625
gene id: 350688:CLOS_RS01625
uniprot id: A8ML55
names: Similarity
messages: Belongs to the NifH/BchL/ChlL family.

350688:CLOS RS08415
gene id: 350688:CLOS_RS08415
uniprot id: A8MGF8
names: Similarity
messages: Belongs to the GSP E family.

350688:CLOS RS14310
gene id: 350688:CLOS_RS14310
uniprot id: A8MKB7
names: Similarity
messages: Belongs to the GerABKA family.

350688:CLOS RS01330
gene id: 350688:CLOS_RS01330
uniprot id: A8MKZ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

350688:CLOS RS07765
gene id: 350688:CLOS_RS07765
uniprot id: A8MHG5
names: Function
names: Similarity
messages: Belongs to the CheD family.
messages: Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.

350688:CLOS RS02355
gene id: 350688:CLOS_RS02355
uniprot id: A8MLU7
names: Similarity
messages: Belongs to the class II ribonucleoside-triphosphate reductase family.

350688:CLOS RS07100
gene id: 350688:CLOS_RS07100
uniprot id: A8MH33
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane

350688:CLOS RS09315
gene id: 350688:CLOS_RS09315
uniprot id: A8MHS5
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

350688:CLOS RS00825
gene id: 350688:CLOS_RS00825
uniprot id: A8MFS6
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily.

350688:CLOS RS13695
gene id: 350688:CLOS_RS13695
uniprot id: A8MJZ4
names: Similarity
messages: Belongs to the FBPase class 2 family.

350688:CLOS RS06620
gene id: 350688:CLOS_RS06620
uniprot id: A8MG99
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

350688:CLOS RS10170
gene id: 350688:CLOS_RS10170
uniprot id: A8MI57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

350688:CLOS RS14820
gene id: 350688:CLOS_RS14820
uniprot id: A8MKL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

350688:CLOS RS07980
gene id: 350688:CLOS_RS07980
uniprot id: A8MFD1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

350688:CLOS RS01850
gene id: 350688:CLOS_RS01850
uniprot id: A8ML99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

350688:CLOS RS03770
gene id: 350688:CLOS_RS03770
uniprot id: A8MMB7
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

350688:CLOS RS06870
gene id: 350688:CLOS_RS06870
uniprot id: A8MGY8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

350688:CLOS RS04845
gene id: 350688:CLOS_RS04845
uniprot id: A8MF08
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

350688:CLOS RS01690
gene id: 350688:CLOS_RS01690
uniprot id: A8ML68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

350688:CLOS RS06880
gene id: 350688:CLOS_RS06880
uniprot id: A8MGZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.

350688:CLOS RS01980
gene id: 350688:CLOS_RS01980
uniprot id: A8MLM4
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.

350688:CLOS RS10475
gene id: 350688:CLOS_RS10475
uniprot id: A8MIB2
names: Function
names: Similarity
messages: Belongs to the alpha/beta-type SASP family.
messages: SASP are bound to spore DNA. They are double-stranded DNA-binding proteins that cause DNA to change to an a-like conformation. They protect the DNA backbone from chemical and enzymatic cleavage and are thus involved in dormant spore's high resistance to UV light.

350688:CLOS RS01915
gene id: 350688:CLOS_RS01915
uniprot id: A8MLL1
names: Similarity
messages: Belongs to the bacterial microcompartments protein family.

350688:CLOS RS09200
gene id: 350688:CLOS_RS09200
uniprot id: A8MHQ2
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

350688:CLOS RS04640
gene id: 350688:CLOS_RS04640
uniprot id: A8MEW7
names: Similarity
messages: Belongs to the manganese catalase family.

350688:CLOS RS12265
gene id: 350688:CLOS_RS12265
uniprot id: A8MJB0
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

350688:CLOS RS07305
gene id: 350688:CLOS_RS07305
uniprot id: A8MH74
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

350688:CLOS RS13940
gene id: 350688:CLOS_RS13940
uniprot id: A8MK43
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

350688:CLOS RS12035
gene id: 350688:CLOS_RS12035
uniprot id: A8MJ64
names: Similarity
messages: Belongs to the GerABKC lipoprotein family.

350688:CLOS RS01275
gene id: 350688:CLOS_RS01275
uniprot id: A8MKY4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase D family. Cardiolipin synthase subfamily.
messages: Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
messages: Cell membrane
messages: Membrane

350688:CLOS RS09310
gene id: 350688:CLOS_RS09310
uniprot id: A8MHS4
names: Similarity
messages: Belongs to the asparaginase 1 family.

350688:CLOS RS06230
gene id: 350688:CLOS_RS06230
uniprot id: A8MF83
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

350688:CLOS RS04345
gene id: 350688:CLOS_RS04345
uniprot id: A8MEQ9
names: Similarity
messages: Belongs to the EamA transporter family.

350688:CLOS RS01950
gene id: 350688:CLOS_RS01950
uniprot id: A8MLL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

350688:CLOS RS09145
gene id: 350688:CLOS_RS09145
uniprot id: A8MHP1
names: Similarity
messages: Belongs to the IMPACT family.

350688:CLOS RS04335
gene id: 350688:CLOS_RS04335
uniprot id: A8MEQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Membrane

350688:CLOS RS02605
gene id: 350688:CLOS_RS02605
uniprot id: A8MLF0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

350688:CLOS RS07065
gene id: 350688:CLOS_RS07065
uniprot id: A8MH25
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

350688:CLOS RS02410
gene id: 350688:CLOS_RS02410
uniprot id: A8MLB1
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

350688:CLOS RS07725
gene id: 350688:CLOS_RS07725
uniprot id: A8MHF7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

350688:CLOS RS10270
gene id: 350688:CLOS_RS10270
uniprot id: A8MI78
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

350688:CLOS RS07595
gene id: 350688:CLOS_RS07595
uniprot id: A8MHD2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CodY family.
messages: Cytoplasm
messages: DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor.

350688:CLOS RS07825
gene id: 350688:CLOS_RS07825
uniprot id: A8MHH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

350688:CLOS RS02650
gene id: 350688:CLOS_RS02650
uniprot id: A8MLF9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

350688:CLOS RS09930
gene id: 350688:CLOS_RS09930
uniprot id: A8MI15
names: Similarity
messages: Belongs to the GSP E family.

350688:CLOS RS12300
gene id: 350688:CLOS_RS12300
uniprot id: A8MJB7
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

350688:CLOS RS06930
gene id: 350688:CLOS_RS06930
uniprot id: A8MH00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

350688:CLOS RS14605
gene id: 350688:CLOS_RS14605
uniprot id: A8MKH4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

350688:CLOS RS04125
gene id: 350688:CLOS_RS04125
uniprot id: A8MEL9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial microcompartment
messages: Belongs to the EutB family.
messages: Binds between the large and small subunits.
messages: Catalyzes the deamination of various vicinal amino-alcohols to oxo compounds. Allows this organism to utilize ethanolamine as the sole source of nitrogen and carbon in the presence of vitamin B12.
messages: The basic unit is a heterodimer which dimerizes to form tetramers. The heterotetramers trimerize; 6 large subunits form a core ring with 6 small subunits projecting outwards.

350688:CLOS RS05635
gene id: 350688:CLOS_RS05635
uniprot id: A8MGU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

350688:CLOS RS07930
gene id: 350688:CLOS_RS07930
uniprot id: A8MFC1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane
messages: This protein catalyzes the committed step to the synthesis of the acidic phospholipids.

350688:CLOS RS04135
gene id: 350688:CLOS_RS04135
uniprot id: A8MEM1
names: Subcellular Location Annotation
messages: Bacterial microcompartment

350688:CLOS RS14005
gene id: 350688:CLOS_RS14005
uniprot id: A8MK56
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

350688:CLOS RS10180
gene id: 350688:CLOS_RS10180
uniprot id: A8MI60
names: Similarity
messages: Belongs to the threonine synthase family.

350688:CLOS RS09560
gene id: 350688:CLOS_RS09560
uniprot id: A8MHU5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

350688:CLOS RS06445
gene id: 350688:CLOS_RS06445
uniprot id: A8MG66
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

350688:CLOS RS02015
gene id: 350688:CLOS_RS02015
uniprot id: A8MLN1
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

350688:CLOS RS12405
gene id: 350688:CLOS_RS12405
uniprot id: A8MJD8
names: Similarity
messages: Belongs to the bacterial microcompartments protein family.

350688:CLOS RS11970
gene id: 350688:CLOS_RS11970
uniprot id: A8MJ51
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. AddB/RexB type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster.
messages: Heterodimer of AddA and AddB.
messages: The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddB nuclease domain is not required for chi fragment generation; this subunit has 5' -> 3' nuclease activity.

350688:CLOS RS12000
gene id: 350688:CLOS_RS12000
uniprot id: A8MJ57
names: Cofactor
messages: Binds 1 zinc ion per subunit.

350688:CLOS RS12280
gene id: 350688:CLOS_RS12280
uniprot id: A8MJB3
names: Similarity
messages: Belongs to the cytochrome c-552 family.

350688:CLOS RS09030
gene id: 350688:CLOS_RS09030
uniprot id: A8MHL8
names: Function
names: Similarity
messages: ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.
messages: Belongs to the ParA family. MinD subfamily.

350688:CLOS RS00440
gene id: 350688:CLOS_RS00440
uniprot id: A8MEG9
names: Cofactor
names: Function
messages: Binds 2 [4Fe-4S] clusters. In this family the first cluster has a non-standard and varying [4Fe-4S] binding motif CX(2)CX(2)CX(4-5)CP.
messages: Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.

350688:CLOS RS01225
gene id: 350688:CLOS_RS01225
uniprot id: A8MKX5
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

350688:CLOS RS02455
gene id: 350688:CLOS_RS02455
uniprot id: A8MLC0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidylate synthase ThyX family.
messages: Binds 4 FAD per tetramer. Each FAD binding site is formed by three monomers.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
messages: Homotetramer.

350688:CLOS RS09790
gene id: 350688:CLOS_RS09790
uniprot id: A8MHY9
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

350688:CLOS RS08645
gene id: 350688:CLOS_RS08645
uniprot id: A8MGK0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase Z family.
messages: Binds 2 Zn(2+) ions.
messages: Homodimer.
messages: Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.

350688:CLOS RS06080
gene id: 350688:CLOS_RS06080
uniprot id: A8MF54
names: Subcellular Location Annotation
messages: Membrane

350688:CLOS RS14190
gene id: 350688:CLOS_RS14190
uniprot id: A8MK93
names: Function
names: Similarity
messages: Belongs to the Thz kinase family.
messages: Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).

350688:CLOS RS02540
gene id: 350688:CLOS_RS02540
uniprot id: A8MLD7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

350688:CLOS RS11020
gene id: 350688:CLOS_RS11020
uniprot id: A8MIL8
names: Similarity
messages: Belongs to the CvfB family.

350688:CLOS RS00905
gene id: 350688:CLOS_RS00905
uniprot id: A8MFU0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

350688:CLOS RS01475
gene id: 350688:CLOS_RS01475
uniprot id: A8ML24
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

350688:CLOS RS14130
gene id: 350688:CLOS_RS14130
uniprot id: A8MK81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

350688:CLOS RS07970
gene id: 350688:CLOS_RS07970
uniprot id: A8MFC9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

350688:CLOS RS11465
gene id: 350688:CLOS_RS11465
uniprot id: A8MIV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

350688:CLOS RS00930
gene id: 350688:CLOS_RS00930
uniprot id: A8MFU5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

350688:CLOS RS11390
gene id: 350688:CLOS_RS11390
uniprot id: A8MIU3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

350688:CLOS RS02090
gene id: 350688:CLOS_RS02090
uniprot id: A8MLP6
names: Similarity
messages: Belongs to the peptidase S66 family.

350688:CLOS RS14915
gene id: 350688:CLOS_RS14915
uniprot id: A8MKN3
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

350688:CLOS RS01520
gene id: 350688:CLOS_RS01520
uniprot id: A8ML34
names: Similarity
messages: Belongs to the GerABKA family.

350688:CLOS RS10585
gene id: 350688:CLOS_RS10585
uniprot id: A8MID4
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

350688:CLOS RS02535
gene id: 350688:CLOS_RS02535
uniprot id: A8MLD6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

350688:CLOS RS11375
gene id: 350688:CLOS_RS11375
uniprot id: A8MIU0
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

350688:CLOS RS06855
gene id: 350688:CLOS_RS06855
uniprot id: A8MGE4
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

350688:CLOS RS10290
gene id: 350688:CLOS_RS10290
uniprot id: A8MI82
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

350688:CLOS RS04565
gene id: 350688:CLOS_RS04565
uniprot id: A8MEV2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Cytoplasm
messages: Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.

350688:CLOS RS12160
gene id: 350688:CLOS_RS12160
uniprot id: A8MJ89
names: Similarity
messages: Belongs to the threonine aldolase family.

350688:CLOS RS07545
gene id: 350688:CLOS_RS07545
uniprot id: A8MHC2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpB which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpB.

350688:CLOS RS07960
gene id: 350688:CLOS_RS07960
uniprot id: A8MFC7
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family.

350688:CLOS RS05395
gene id: 350688:CLOS_RS05395
uniprot id: A8MGP8
names: Similarity
messages: Belongs to the band 7/mec-2 family. Flotillin subfamily.

350688:CLOS RS08290
gene id: 350688:CLOS_RS08290
uniprot id: A8MFJ3
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

350688:CLOS RS12270
gene id: 350688:CLOS_RS12270
uniprot id: A8MJB1
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit A family.

350688:CLOS RS02115
gene id: 350688:CLOS_RS02115
uniprot id: A8MLQ1
names: Similarity
messages: Belongs to the hemerythrin family.

350688:CLOS RS03325
gene id: 350688:CLOS_RS03325
uniprot id: A8MM29
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

350688:CLOS RS05550
gene id: 350688:CLOS_RS05550
uniprot id: A8MGS7
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

350688:CLOS RS00215
gene id: 350688:CLOS_RS00215
uniprot id: A8MED5
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

350688:CLOS RS10085
gene id: 350688:CLOS_RS10085
uniprot id: A8MI42
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

350688:CLOS RS07260
gene id: 350688:CLOS_RS07260
uniprot id: A8MH65
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SepF family.
messages: Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

350688:CLOS RS13430
gene id: 350688:CLOS_RS13430
uniprot id: A8MJU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Membrane

350688:CLOS RS01005
gene id: 350688:CLOS_RS01005
uniprot id: A8MKT2
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

350688:CLOS RS00795
gene id: 350688:CLOS_RS00795
uniprot id: A8MFS0
names: Subcellular Location Annotation
messages: Membrane

350688:CLOS RS07315
gene id: 350688:CLOS_RS07315
uniprot id: A8MH76
names: Function
names: Similarity
names: Subunit
messages: Associates with stalled 50S ribosomal subunits.
messages: Belongs to the NEMF family.
messages: Part of the ribosome quality control system (RQC). Recruits Ala-charged tRNA and directs the elongation of stalled nascent chains on 50S ribosomal subunits, leading to non-templated C-terminal Ala extensions (Ala tail). The Ala tail promotes nascent chain degradation. May add between 1 and at least 8 Ala residues. Binds to stalled 50S ribosomal subunits.

350688:CLOS RS04215
gene id: 350688:CLOS_RS04215
uniprot id: A8MEN7
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

350688:CLOS RS03980
gene id: 350688:CLOS_RS03980
uniprot id: A8MEJ2
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

350688:CLOS RS13060
gene id: 350688:CLOS_RS13060
uniprot id: A8MJL7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

350688:CLOS RS07230
gene id: 350688:CLOS_RS07230
uniprot id: A8MH59
names: Function
names: Subcellular Location Annotation
messages: ATPase. Has a role at an early stage in the morphogenesis of the spore coat.
messages: Cytoplasm

350688:CLOS RS07720
gene id: 350688:CLOS_RS07720
uniprot id: A8MHF6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type III secretion exporter family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

350688:CLOS RS07310
gene id: 350688:CLOS_RS07310
uniprot id: A8MH75
names: Function
names: Similarity
names: Subunit
messages: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
messages: Homodimer and homohexamer; in equilibrium.
messages: Regulates transcriptional attenuation of the pyrimidine nucleotide (pyr) operon by binding in a uridine-dependent manner to specific sites on pyr mRNA. This disrupts an antiterminator hairpin in the RNA and favors formation of a downstream transcription terminator, leading to a reduced expression of downstream genes.

350688:CLOS RS01655
gene id: 350688:CLOS_RS01655
uniprot id: A8ML61
names: Similarity
messages: Belongs to the GerABKC lipoprotein family.

350688:CLOS RS13570
gene id: 350688:CLOS_RS13570
uniprot id: A8MJW9
names: Subcellular Location Annotation
messages: Membrane

350688:CLOS RS03015
gene id: 350688:CLOS_RS03015
uniprot id: A8MLW9
names: Function
names: Similarity
messages: Belongs to the RapZ-like family.
messages: Displays ATPase and GTPase activities.

350688:CLOS RS06865
gene id: 350688:CLOS_RS06865
uniprot id: A8MGY7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen.
messages: Homooctamer.

350688:CLOS RS00045
gene id: 350688:CLOS_RS00045
uniprot id: A8MEA6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

350688:CLOS RS05970
gene id: 350688:CLOS_RS05970
uniprot id: A8MF33
names: Similarity
messages: Belongs to the peptidase M24B family.

350688:CLOS RS11050
gene id: 350688:CLOS_RS11050
uniprot id: A8MIM4
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.

350688:CLOS RS02025
gene id: 350688:CLOS_RS02025
uniprot id: A8MLN3
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

350688:CLOS RS11980
gene id: 350688:CLOS_RS11980
uniprot id: A8MJ53
names: Similarity
messages: Belongs to the UPF0371 family.

350688:CLOS RS07075
gene id: 350688:CLOS_RS07075
uniprot id: A8MH28
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

350688:CLOS RS02045
gene id: 350688:CLOS_RS02045
uniprot id: A8MLN7
names: Subcellular Location Annotation
messages: Membrane

350688:CLOS RS05045
gene id: 350688:CLOS_RS05045
uniprot id: A8MFY7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

350688:CLOS RS02435
gene id: 350688:CLOS_RS02435
uniprot id: A8MLB6
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

350688:CLOS RS12185
gene id: 350688:CLOS_RS12185
uniprot id: A8MJ94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

350688:CLOS RS03485
gene id: 350688:CLOS_RS03485
uniprot id: A8MM60
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

350688:CLOS RS05795
gene id: 350688:CLOS_RS05795
uniprot id: A8MGX4
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

350688:CLOS RS00715
gene id: 350688:CLOS_RS00715
uniprot id: A8MFQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

350688:CLOS RS14395
gene id: 350688:CLOS_RS14395
uniprot id: A8MKD3
names: Similarity
messages: Belongs to the YjdM family.

350688:CLOS RS15090
gene id: 350688:CLOS_RS15090
uniprot id: A8MKR7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

350688:CLOS RS06005
gene id: 350688:CLOS_RS06005
uniprot id: A8MF40
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

350688:CLOS RS13195
gene id: 350688:CLOS_RS13195
uniprot id: A8MJP4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

350688:CLOS RS02660
gene id: 350688:CLOS_RS02660
uniprot id: A8MLG1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Monomer.

350688:CLOS RS11755
gene id: 350688:CLOS_RS11755
uniprot id: A8MJ10
names: Similarity
messages: Belongs to the peptidase S41A family.

350688:CLOS RS10970
gene id: 350688:CLOS_RS10970
uniprot id: A8MIK8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ApbE family.
messages: Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.
messages: Magnesium. Can also use manganese.

350688:CLOS RS02520
gene id: 350688:CLOS_RS02520
uniprot id: A8MLD3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

350688:CLOS RS07620
gene id: 350688:CLOS_RS07620
uniprot id: A8MHD7
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Membrane

350688:CLOS RS06470
gene id: 350688:CLOS_RS06470
uniprot id: A8MG71
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

350688:CLOS RS05510
gene id: 350688:CLOS_RS05510
uniprot id: A8MGR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

350688:CLOS RS02640
gene id: 350688:CLOS_RS02640
uniprot id: A8MLF7
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

350688:CLOS RS02720
gene id: 350688:CLOS_RS02720
uniprot id: A8MLH3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the energy-coupling factor EcfT family.
messages: Cell membrane
messages: Forms a stable energy-coupling factor (ECF) transporter complex composed of 2 membrane-embedded substrate-binding proteins (S component), 2 ATP-binding proteins (A component) and 2 transmembrane proteins (T component).
messages: Membrane
messages: Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.

350688:CLOS RS13555
gene id: 350688:CLOS_RS13555
uniprot id: A8MJW6
names: Subcellular Location Annotation
messages: Membrane

350688:CLOS RS10580
gene id: 350688:CLOS_RS10580
uniprot id: A8MID3
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

350688:CLOS RS09090
gene id: 350688:CLOS_RS09090
uniprot id: A8MHN0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

350688:CLOS RS09065
gene id: 350688:CLOS_RS09065
uniprot id: A8MHM5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

350688:CLOS RS00015
gene id: 350688:CLOS_RS00015
uniprot id: A8MEA0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

350688:CLOS RS07820
gene id: 350688:CLOS_RS07820
uniprot id: A8MHH5
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).

350688:CLOS RS08150
gene id: 350688:CLOS_RS08150
uniprot id: A8MFG5
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

350688:CLOS RS08040
gene id: 350688:CLOS_RS08040
uniprot id: A8MFE3
names: Domain
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

350688:CLOS RS11405
gene id: 350688:CLOS_RS11405
uniprot id: A8MIU6
names: Similarity
messages: Belongs to the OMP decarboxylase family. Type 2 subfamily.

350688:CLOS RS11340
gene id: 350688:CLOS_RS11340
uniprot id: A8MIT3
names: Similarity
messages: In the N-terminal section; belongs to the zinc metallo-hydrolase group 3 family.

350688:CLOS RS12325
gene id: 350688:CLOS_RS12325
uniprot id: A8MJC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

350688:CLOS RS10100
gene id: 350688:CLOS_RS10100
uniprot id: A8MI45
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

350688:CLOS RS15075
gene id: 350688:CLOS_RS15075
uniprot id: A8MKR4
names: Similarity
messages: Belongs to the ParB family.

350688:CLOS RS05010
gene id: 350688:CLOS_RS05010
uniprot id: A8MFY0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

350688:CLOS RS02300
gene id: 350688:CLOS_RS02300
uniprot id: A8MLT9
names: Function
names: Similarity
messages: Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor.
messages: Belongs to the biotin--protein ligase family.

350688:CLOS RS13160
gene id: 350688:CLOS_RS13160
uniprot id: A8MJN7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

350688:CLOS RS10550
gene id: 350688:CLOS_RS10550
uniprot id: A8MIC7
names: Similarity
messages: Belongs to the GbsR family.

350688:CLOS RS06800
gene id: 350688:CLOS_RS06800
uniprot id: A8MGD4
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

350688:CLOS RS14165
gene id: 350688:CLOS_RS14165
uniprot id: A8MK88
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

350688:CLOS RS13585
gene id: 350688:CLOS_RS13585
uniprot id: A8MJX2
names: Similarity
messages: Belongs to the LacAB/RpiB family.

350688:CLOS RS14030
gene id: 350688:CLOS_RS14030
uniprot id: A8MK61
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

350688:CLOS RS08210
gene id: 350688:CLOS_RS08210
uniprot id: A8MFH7
names: Subcellular Location Annotation
messages: Membrane

350688:CLOS RS04695
gene id: 350688:CLOS_RS04695
uniprot id: A8MEX8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

350688:CLOS RS08165
gene id: 350688:CLOS_RS08165
uniprot id: A8MFG8
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

350688:CLOS RS08620
gene id: 350688:CLOS_RS08620
uniprot id: A8MGJ5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

350688:CLOS RS01675
gene id: 350688:CLOS_RS01675
uniprot id: A8ML65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

350688:CLOS RS12925
gene id: 350688:CLOS_RS12925
uniprot id: A8MJI9
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

350688:CLOS RS02855
gene id: 350688:CLOS_RS02855
uniprot id: A8MLJ8
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

350688:CLOS RS06200
gene id: 350688:CLOS_RS06200
uniprot id: A8MF78
names: Subcellular Location Annotation
messages: Membrane

350688:CLOS RS07510
gene id: 350688:CLOS_RS07510
uniprot id: A8MHB5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

350688:CLOS RS02030
gene id: 350688:CLOS_RS02030
uniprot id: A8MLN4
names: Subcellular Location Annotation
messages: Membrane

350688:CLOS RS10155
gene id: 350688:CLOS_RS10155
uniprot id: A8MI54
names: Subcellular Location Annotation
messages: Membrane

350688:CLOS RS07715
gene id: 350688:CLOS_RS07715
uniprot id: A8MHF5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

350688:CLOS RS03195
gene id: 350688:CLOS_RS03195
uniprot id: A8MM03
names: Subcellular Location Annotation
messages: Membrane

350688:CLOS RS00300
gene id: 350688:CLOS_RS00300
uniprot id: A8MEE8
names: Cofactor
names: Function
names: Subunit
messages: Binds 2 [4Fe-4S] clusters. In this family the first cluster has a non-standard and varying [4Fe-4S] binding motif CX(2)CX(2)CX(4-5)CP.
messages: Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.
messages: Heterodimer of the IorA and IorB subunits.

350688:CLOS RS11880
gene id: 350688:CLOS_RS11880
uniprot id: A8MJ34
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

350688:CLOS RS04440
gene id: 350688:CLOS_RS04440
uniprot id: A8MES8
names: Subcellular Location Annotation
messages: Membrane

350688:CLOS RS08230
gene id: 350688:CLOS_RS08230
uniprot id: A8MFI1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

350688:CLOS RS04995
gene id: 350688:CLOS_RS04995
uniprot id: A8MFX7
names: Similarity
messages: Belongs to the SorC transcriptional regulatory family.

350688:CLOS RS03295
gene id: 350688:CLOS_RS03295
uniprot id: A8MM23
names: Subcellular Location Annotation
messages: Membrane

350688:CLOS RS11150
gene id: 350688:CLOS_RS11150
uniprot id: A8MIP4
names: Similarity
messages: Belongs to the AOR/FOR family.

350688:CLOS RS04555
gene id: 350688:CLOS_RS04555
uniprot id: A8MEV0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MntP (TC 9.B.29) family.
messages: Cell membrane
messages: Probably functions as a manganese efflux pump.

350688:CLOS RS07085
gene id: 350688:CLOS_RS07085
uniprot id: A8MH30
names: Similarity
messages: Belongs to the transpeptidase family.

350688:CLOS RS04810
gene id: 350688:CLOS_RS04810
uniprot id: A8MF01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

350688:CLOS RS08350
gene id: 350688:CLOS_RS08350
uniprot id: A8MFK5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Monomer.

350688:CLOS RS08500
gene id: 350688:CLOS_RS08500
uniprot id: A8MGH1
names: Similarity
messages: Belongs to the transpeptidase family.

350688:CLOS RS05295
gene id: 350688:CLOS_RS05295
uniprot id: A8MG37
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

350688:CLOS RS03035
gene id: 350688:CLOS_RS03035
uniprot id: A8MLX3
names: Function
names: Similarity
messages: Belongs to the WhiA family.
messages: Involved in cell division and chromosome segregation.

350688:CLOS RS13550
gene id: 350688:CLOS_RS13550
uniprot id: A8MJW5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

350688:CLOS RS02700
gene id: 350688:CLOS_RS02700
uniprot id: A8MLG9
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

350688:CLOS RS05920
gene id: 350688:CLOS_RS05920
uniprot id: A8MF22
names: Function
names: Similarity
messages: Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.

350688:CLOS RS07810
gene id: 350688:CLOS_RS07810
uniprot id: A8MHH3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

350688:CLOS RS07415
gene id: 350688:CLOS_RS07415
uniprot id: A8MH96
names: Similarity
messages: Belongs to the asp23 family.

350688:CLOS RS03900
gene id: 350688:CLOS_RS03900
uniprot id: A8MEH6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

350688:CLOS RS01010
gene id: 350688:CLOS_RS01010
uniprot id: A8MKT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

350688:CLOS RS02580
gene id: 350688:CLOS_RS02580
uniprot id: A8MLE5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity).

350688:CLOS RS12870
gene id: 350688:CLOS_RS12870
uniprot id: A8MJH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

350688:CLOS RS04675
gene id: 350688:CLOS_RS04675
uniprot id: A8MEX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Cell membrane
messages: Membrane

350688:CLOS RS09255
gene id: 350688:CLOS_RS09255
uniprot id: A8MHR3
names: Subcellular Location Annotation
messages: Membrane

350688:CLOS RS11565
gene id: 350688:CLOS_RS11565
uniprot id: A8MIX7
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
messages: Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.

350688:CLOS RS08180
gene id: 350688:CLOS_RS08180
uniprot id: A8MFH1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: Homotrimer.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.

350688:CLOS RS13400
gene id: 350688:CLOS_RS13400
uniprot id: A8MJT5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

350688:CLOS RS11295
gene id: 350688:CLOS_RS11295
uniprot id: A8MIS3
names: Similarity
messages: Belongs to the EamA transporter family.

350688:CLOS RS08735
gene id: 350688:CLOS_RS08735
uniprot id: A8MGL8
names: Similarity
messages: Belongs to the ThrE exporter (TC 2.A.79) family.

350688:CLOS RS10945
gene id: 350688:CLOS_RS10945
uniprot id: A8MIK4
names: Caution
names: Function
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

350688:CLOS RS01455
gene id: 350688:CLOS_RS01455
uniprot id: A8ML20
names: Subcellular Location Annotation
messages: Membrane

350688:CLOS RS13340
gene id: 350688:CLOS_RS13340
uniprot id: A8MJS2
names: Similarity
messages: Belongs to the FlgM family.

350688:CLOS RS06820
gene id: 350688:CLOS_RS06820
uniprot id: A8MGD7
names: Similarity
messages: Belongs to the UPF0758 family.

350688:CLOS RS10175
gene id: 350688:CLOS_RS10175
uniprot id: A8MI59
names: Cofactor
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.
messages: Binds 3 [4Fe-4S] clusters per subunit.

350688:CLOS RS07785
gene id: 350688:CLOS_RS07785
uniprot id: A8MHG9
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

350688:CLOS RS08395
gene id: 350688:CLOS_RS08395
uniprot id: A8MGF4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Plays an essential role in type IV pili and type II pseudopili formation by proteolytically removing the leader sequence from substrate proteins and subsequently monomethylating the alpha-amino group of the newly exposed N-terminal phenylalanine.

350688:CLOS RS12230
gene id: 350688:CLOS_RS12230
uniprot id: A8MJA3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

350688:CLOS RS05860
gene id: 350688:CLOS_RS05860
uniprot id: A8MF12
names: Function
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. NagD family.
messages: Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro.

350688:CLOS RS08410
gene id: 350688:CLOS_RS08410
uniprot id: A8MGF7
names: Similarity
messages: Belongs to the GSP E family.

350688:CLOS RS07830
gene id: 350688:CLOS_RS07830
uniprot id: A8MHH7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

350688:CLOS RS02490
gene id: 350688:CLOS_RS02490
uniprot id: A8MLC7
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

350688:CLOS RS15120
gene id: 350688:CLOS_RS15120
uniprot id: A8MKS4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

350688:CLOS RS05060
gene id: 350688:CLOS_RS05060
uniprot id: A8MFZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family.
messages: Cell membrane
messages: Membrane

350688:CLOS RS07425
gene id: 350688:CLOS_RS07425
uniprot id: A8MH98
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

350688:CLOS RS07565
gene id: 350688:CLOS_RS07565
uniprot id: A8MHC6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
messages: Cytoplasm
messages: Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity.

350688:CLOS RS02990
gene id: 350688:CLOS_RS02990
uniprot id: A8MLW4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Cytoplasm
messages: Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.

350688:CLOS RS14440
gene id: 350688:CLOS_RS14440
uniprot id: A8MKE2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

350688:CLOS RS01530
gene id: 350688:CLOS_RS01530
uniprot id: A8ML36
names: Similarity
messages: Belongs to the GerABKC lipoprotein family.

350688:CLOS RS12015
gene id: 350688:CLOS_RS12015
uniprot id: A8MJ60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Cell membrane
messages: Membrane

350688:CLOS RS02655
gene id: 350688:CLOS_RS02655
uniprot id: A8MLG0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

350688:CLOS RS10460
gene id: 350688:CLOS_RS10460
uniprot id: A8MIA9
names: Similarity
messages: Belongs to the YciI family.

350688:CLOS RS02430
gene id: 350688:CLOS_RS02430
uniprot id: A8MLB5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Monomer.

350688:CLOS RS07375
gene id: 350688:CLOS_RS07375
uniprot id: A8MH88
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.

350688:CLOS RS07890
gene id: 350688:CLOS_RS07890
uniprot id: A8MFB3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

350688:CLOS RS09170
gene id: 350688:CLOS_RS09170
uniprot id: A8MHP6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cell membrane
messages: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.
messages: Membrane

350688:CLOS RS08860
gene id: 350688:CLOS_RS08860
uniprot id: A8MHI5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RuvC family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.

350688:CLOS RS11010
gene id: 350688:CLOS_RS11010
uniprot id: A8MIL6
names: Similarity
messages: Belongs to the asp23 family.

350688:CLOS RS10770
gene id: 350688:CLOS_RS10770
uniprot id: A8MIG9
names: Subcellular Location Annotation
messages: Membrane

350688:CLOS RS02770
gene id: 350688:CLOS_RS02770
uniprot id: A8MLI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

350688:CLOS RS13960
gene id: 350688:CLOS_RS13960
uniprot id: A8MK47
names: Similarity
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.

350688:CLOS RS07605
gene id: 350688:CLOS_RS07605
uniprot id: A8MHD4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

350688:CLOS RS07150
gene id: 350688:CLOS_RS07150
uniprot id: A8MH43
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase U4 family.
messages: Cell membrane
messages: Probable aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE/spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR.

350688:CLOS RS05015
gene id: 350688:CLOS_RS05015
uniprot id: A8MFY1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

350688:CLOS RS12285
gene id: 350688:CLOS_RS12285
uniprot id: A8MJB4
names: Subcellular Location Annotation
messages: Membrane

350688:CLOS RS08670
gene id: 350688:CLOS_RS08670
uniprot id: A8MGK5
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

350688:CLOS RS12205
gene id: 350688:CLOS_RS12205
uniprot id: A8MJ98
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

350688:CLOS RS07635
gene id: 350688:CLOS_RS07635
uniprot id: A8MHE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliJ family.
messages: Cell membrane
messages: Membrane

350688:CLOS RS02545
gene id: 350688:CLOS_RS02545
uniprot id: A8MLC4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

350688:CLOS RS00700
gene id: 350688:CLOS_RS00700
uniprot id: A8MFQ1
names: Subcellular Location Annotation
messages: Membrane

350688:CLOS RS12935
gene id: 350688:CLOS_RS12935
uniprot id: A8MJJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

350688:CLOS RS10575
gene id: 350688:CLOS_RS10575
uniprot id: A8MID2
names: Similarity
messages: Belongs to the cycloisomerase 2 family.

350688:CLOS RS02570
gene id: 350688:CLOS_RS02570
uniprot id: A8MLE3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

350688:CLOS RS10285
gene id: 350688:CLOS_RS10285
uniprot id: A8MI81
names: Subcellular Location Annotation
messages: Membrane

350688:CLOS RS14610
gene id: 350688:CLOS_RS14610
uniprot id: A8MKH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Membrane

350688:CLOS RS04825
gene id: 350688:CLOS_RS04825
uniprot id: A8MF04
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

350688:CLOS RS02370
gene id: 350688:CLOS_RS02370
uniprot id: A8MLV0
names: Activity Regulation
names: Function
names: Similarity
messages: Appears to be allosterically activated by the binding of pArg-containing polypeptides to the pArg-binding pocket localized in the C-terminal domain of McsB.
messages: Belongs to the ATP:guanido phosphotransferase family.
messages: Catalyzes the specific phosphorylation of arginine residues in proteins.

350688:CLOS RS02785
gene id: 350688:CLOS_RS02785
uniprot id: A8MLI6
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

350688:CLOS RS01540
gene id: 350688:CLOS_RS01540
uniprot id: A8ML38
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

350688:CLOS RS02730
gene id: 350688:CLOS_RS02730
uniprot id: A8MLH5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

350688:CLOS RS07790
gene id: 350688:CLOS_RS07790
uniprot id: A8MHH0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

350688:CLOS RS01660
gene id: 350688:CLOS_RS01660
uniprot id: A8ML62
names: Similarity
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2.A.3.9) family.

350688:CLOS RS01135
gene id: 350688:CLOS_RS01135
uniprot id: A8MKV7
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

350688:CLOS RS02055
gene id: 350688:CLOS_RS02055
uniprot id: A8MLN9
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

350688:CLOS RS07345
gene id: 350688:CLOS_RS07345
uniprot id: A8MH82
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

350688:CLOS RS08345
gene id: 350688:CLOS_RS08345
uniprot id: A8MFK4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

350688:CLOS RS03020
gene id: 350688:CLOS_RS03020
uniprot id: A8MLX0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gluconeogenesis factor family.
messages: Cytoplasm
messages: Required for morphogenesis under gluconeogenic growth conditions.

350688:CLOS RS04900
gene id: 350688:CLOS_RS04900
uniprot id: A8MFW0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Could methylate the ribose at the nucleotide 34 wobble position in tRNA.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

350688:CLOS RS05710
gene id: 350688:CLOS_RS05710
uniprot id: A8MGV7
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

350688:CLOS RS11765
gene id: 350688:CLOS_RS11765
uniprot id: A8MJ12
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation.

350688:CLOS RS14785
gene id: 350688:CLOS_RS14785
uniprot id: A8MKL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

350688:CLOS RS13605
gene id: 350688:CLOS_RS13605
uniprot id: A8MJX6
names: Subcellular Location Annotation
messages: Membrane

350688:CLOS RS07360
gene id: 350688:CLOS_RS07360
uniprot id: A8MH85
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

350688:CLOS RS07215
gene id: 350688:CLOS_RS07215
uniprot id: A8MH56
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

350688:CLOS RS04075
gene id: 350688:CLOS_RS04075
uniprot id: A8MEK9
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

350688:CLOS RS13810
gene id: 350688:CLOS_RS13810
uniprot id: A8MK17
names: Subcellular Location Annotation
messages: Membrane

350688:CLOS RS12415
gene id: 350688:CLOS_RS12415
uniprot id: A8MJE0
names: Similarity
messages: Belongs to the bacterial microcompartments protein family.

350688:CLOS RS06365
gene id: 350688:CLOS_RS06365
uniprot id: A8MG50
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

350688:CLOS RS13930
gene id: 350688:CLOS_RS13930
uniprot id: A8MK41
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

350688:CLOS RS12070
gene id: 350688:CLOS_RS12070
uniprot id: A8MJ71
names: Similarity
messages: Belongs to the EamA transporter family.

350688:CLOS RS05560
gene id: 350688:CLOS_RS05560
uniprot id: A8MGS9
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. YrrT family.
messages: Could be a S-adenosyl-L-methionine-dependent methyltransferase.

350688:CLOS RS00485
gene id: 350688:CLOS_RS00485
uniprot id: A8MFK9
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

350688:CLOS RS11495
gene id: 350688:CLOS_RS11495
uniprot id: A8MIW3
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

350688:CLOS RS07020
gene id: 350688:CLOS_RS07020
uniprot id: A8MH16
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Monomer.

350688:CLOS RS12170
gene id: 350688:CLOS_RS12170
uniprot id: A8MJ91
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

350688:CLOS RS06050
gene id: 350688:CLOS_RS06050
uniprot id: A8MF48
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

350688:CLOS RS13765
gene id: 350688:CLOS_RS13765
uniprot id: A8MK08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

350688:CLOS RS09515
gene id: 350688:CLOS_RS09515
uniprot id: A8MHT6
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

350688:CLOS RS13170
gene id: 350688:CLOS_RS13170
uniprot id: A8MJN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

350688:CLOS RS05855
gene id: 350688:CLOS_RS05855
uniprot id: A8MGY6
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

350688:CLOS RS05020
gene id: 350688:CLOS_RS05020
uniprot id: A8MFY2
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

350688:CLOS RS11500
gene id: 350688:CLOS_RS11500
uniprot id: A8MIW4
names: Function
messages: Decarboxylates L-threonine-O-3-phosphate to yield (R)-1-amino-2-propanol O-2-phosphate, the precursor for the linkage between the nucleotide loop and the corrin ring in cobalamin.

350688:CLOS RS00040
gene id: 350688:CLOS_RS00040
uniprot id: A8MEA5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

350688:CLOS RS07885
gene id: 350688:CLOS_RS07885
uniprot id: A8MFB2
names: Similarity
messages: Belongs to the ribF family.

350688:CLOS RS13030
gene id: 350688:CLOS_RS13030
uniprot id: A8MJL0
names: Similarity
messages: Belongs to the asp23 family.

350688:CLOS RS09120
gene id: 350688:CLOS_RS09120
uniprot id: A8MHN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

350688:CLOS RS02825
gene id: 350688:CLOS_RS02825
uniprot id: A8MLJ3
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids threonine, isoleucine and methionine.

350688:CLOS RS13315
gene id: 350688:CLOS_RS13315
uniprot id: A8MJR8
names: Subcellular Location Annotation
messages: Membrane

350688:CLOS RS12305
gene id: 350688:CLOS_RS12305
uniprot id: A8MJB8
names: Similarity
messages: Belongs to the PRORSD1 family.

350688:CLOS RS03265
gene id: 350688:CLOS_RS03265
uniprot id: A8MM17
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

350688:CLOS RS10895
gene id: 350688:CLOS_RS10895
uniprot id: A8MIJ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

350688:CLOS RS05700
gene id: 350688:CLOS_RS05700
uniprot id: A8MGV5
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

350688:CLOS RS11065
gene id: 350688:CLOS_RS11065
uniprot id: A8MIM7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

350688:CLOS RS13625
gene id: 350688:CLOS_RS13625
uniprot id: A8MJY0
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

350688:CLOS RS07090
gene id: 350688:CLOS_RS07090
uniprot id: A8MH31
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm

350688:CLOS RS10240
gene id: 350688:CLOS_RS10240
uniprot id: A8MI72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.
messages: Cell membrane

350688:CLOS RS03740
gene id: 350688:CLOS_RS03740
uniprot id: A8MMB1
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

350688:CLOS RS02685
gene id: 350688:CLOS_RS02685
uniprot id: A8MLG6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

350688:CLOS RS02440
gene id: 350688:CLOS_RS02440
uniprot id: A8MLB7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

350688:CLOS RS12875
gene id: 350688:CLOS_RS12875
uniprot id: A8MJI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

350688:CLOS RS05040
gene id: 350688:CLOS_RS05040
uniprot id: A8MFY6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

350688:CLOS RS13845
gene id: 350688:CLOS_RS13845
uniprot id: A8MK24
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

350688:CLOS RS11835
gene id: 350688:CLOS_RS11835
uniprot id: A8MJ26
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

350688:CLOS RS03885
gene id: 350688:CLOS_RS03885
uniprot id: A8MMD5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

350688:CLOS RS00210
gene id: 350688:CLOS_RS00210
uniprot id: A8MED4
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

350688:CLOS RS13990
gene id: 350688:CLOS_RS13990
uniprot id: A8MK53
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

350688:CLOS RS14390
gene id: 350688:CLOS_RS14390
uniprot id: A8MKD2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the kynureninase family.
messages: Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

350688:CLOS RS05065
gene id: 350688:CLOS_RS05065
uniprot id: A8MFZ1
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

350688:CLOS RS06385
gene id: 350688:CLOS_RS06385
uniprot id: A8MG54
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

350688:CLOS RS06380
gene id: 350688:CLOS_RS06380
uniprot id: A8MG53
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

350688:CLOS RS02995
gene id: 350688:CLOS_RS02995
uniprot id: A8MLW5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

350688:CLOS RS13805
gene id: 350688:CLOS_RS13805
uniprot id: A8MK16
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

350688:CLOS RS07225
gene id: 350688:CLOS_RS07225
uniprot id: A8MH58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

350688:CLOS RS08110
gene id: 350688:CLOS_RS08110
uniprot id: A8MFF7
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

350688:CLOS RS10220
gene id: 350688:CLOS_RS10220
uniprot id: A8MI68
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

350688:CLOS RS13700
gene id: 350688:CLOS_RS13700
uniprot id: A8MJZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 3B subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

350688:CLOS RS07615
gene id: 350688:CLOS_RS07615
uniprot id: A8MHD6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.

350688:CLOS RS02695
gene id: 350688:CLOS_RS02695
uniprot id: A8MLG8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

350688:CLOS RS06460
gene id: 350688:CLOS_RS06460
uniprot id: A8MG69
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

350688:CLOS RS12395
gene id: 350688:CLOS_RS12395
uniprot id: A8MJD6
names: Function
names: Similarity
messages: Belongs to the PduL family.
messages: Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate.

350688:CLOS RS11225
gene id: 350688:CLOS_RS11225
uniprot id: A8MIQ9
names: Similarity
messages: Belongs to the type IA topoisomerase family.

350688:CLOS RS07580
gene id: 350688:CLOS_RS07580
uniprot id: A8MHC9
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

350688:CLOS RS06270
gene id: 350688:CLOS_RS06270
uniprot id: A8MF90
names: Similarity
messages: Belongs to the hemerythrin family.

350688:CLOS RS00985
gene id: 350688:CLOS_RS00985
uniprot id: A8MKS8
names: Subcellular Location Annotation
messages: Membrane

350688:CLOS RS06415
gene id: 350688:CLOS_RS06415
uniprot id: A8MG60
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the flotillin-like FloA family.
messages: Cell membrane
messages: Found in functional membrane microdomains (FMM) that may be equivalent to eukaryotic membrane rafts. FMMs are highly dynamic and increase in number as cells age. Flotillins are thought to be important factors in membrane fluidity.
messages: Homooligomerizes.
messages: Membrane raft

350688:CLOS RS00425
gene id: 350688:CLOS_RS00425
uniprot id: A8MEG6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. N-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

350688:CLOS RS05250
gene id: 350688:CLOS_RS05250
uniprot id: A8MG28
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

350688:CLOS RS05850
gene id: 350688:CLOS_RS05850
uniprot id: A8MGY5
names: Subcellular Location Annotation
messages: Membrane

350688:CLOS RS08175
gene id: 350688:CLOS_RS08175
uniprot id: A8MFH0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: Homotrimer.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.

350688:CLOS RS13440
gene id: 350688:CLOS_RS13440
uniprot id: A8MJU3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PdxA family. PdxA2 subfamily.
messages: Catalyzes the NAD-dependent oxidation and subsequent decarboxylation of D-threonate 4-phosphate to produce dihydroxyacetone phosphate (DHAP).
messages: Homodimer.

350688:CLOS RS11885
gene id: 350688:CLOS_RS11885
uniprot id: A8MJ35
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

350688:CLOS RS12970
gene id: 350688:CLOS_RS12970
uniprot id: A8MJJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

350688:CLOS RS01060
gene id: 350688:CLOS_RS01060
uniprot id: A8MKU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

350688:CLOS RS00940
gene id: 350688:CLOS_RS00940
uniprot id: A8MFU7
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

350688:CLOS RS02775
gene id: 350688:CLOS_RS02775
uniprot id: A8MLI4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

350688:CLOS RS02000
gene id: 350688:CLOS_RS02000
uniprot id: A8MLM8
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

350688:CLOS RS00455
gene id: 350688:CLOS_RS00455
uniprot id: A8MEH2
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

350688:CLOS RS13565
gene id: 350688:CLOS_RS13565
uniprot id: A8MJW8
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

350688:CLOS RS07115
gene id: 350688:CLOS_RS07115
uniprot id: A8MH36
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).

350688:CLOS RS11895
gene id: 350688:CLOS_RS11895
uniprot id: A8MJ37
names: Subcellular Location Annotation
messages: Membrane

350688:CLOS RS02240
gene id: 350688:CLOS_RS02240
uniprot id: A8MLS7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

350688:CLOS RS09660
gene id: 350688:CLOS_RS09660
uniprot id: A8MHW3
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

350688:CLOS RS02875
gene id: 350688:CLOS_RS02875
uniprot id: A8MLK1
names: Similarity
messages: Belongs to the HypE family.

350688:CLOS RS07675
gene id: 350688:CLOS_RS07675
uniprot id: A8MHE8
names: Similarity
messages: Belongs to the MotB family.

350688:CLOS RS08270
gene id: 350688:CLOS_RS08270
uniprot id: A8MFI9
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

350688:CLOS RS02065
gene id: 350688:CLOS_RS02065
uniprot id: A8MLP1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

350688:CLOS RS05075
gene id: 350688:CLOS_RS05075
uniprot id: A8MFZ3
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

350688:CLOS RS03410
gene id: 350688:CLOS_RS03410
uniprot id: A8MM45
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pseudouridine-5'-phosphate glycosidase family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the reversible cleavage of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway.
messages: Homotrimer.

350688:CLOS RS05765
gene id: 350688:CLOS_RS05765
uniprot id: A8MGW8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PstS family.
messages: Cell membrane
messages: Involved in the system for phosphate transport across the cytoplasmic membrane.
messages: Membrane
messages: Part of the ABC transporter complex PstSACB involved in phosphate import.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

350688:CLOS RS03055
gene id: 350688:CLOS_RS03055
uniprot id: A8MLX7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
messages: Cytoplasm

350688:CLOS RS12030
gene id: 350688:CLOS_RS12030
uniprot id: A8MJ63
names: Similarity
messages: Belongs to the GerABKA family.

350688:CLOS RS03235
gene id: 350688:CLOS_RS03235
uniprot id: A8MM11
names: Similarity
messages: Belongs to the Fur family.

350688:CLOS RS08245
gene id: 350688:CLOS_RS08245
uniprot id: A8MFI4
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

350688:CLOS RS12390
gene id: 350688:CLOS_RS12390
uniprot id: A8MJD5
names: Similarity
messages: Belongs to the bacterial microcompartments protein family.

350688:CLOS RS12500
gene id: 350688:CLOS_RS12500
uniprot id: A8MJF7
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

350688:CLOS RS08610
gene id: 350688:CLOS_RS08610
uniprot id: A8MGJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Molecular chaperone. Has ATPase activity.

350688:CLOS RS13545
gene id: 350688:CLOS_RS13545
uniprot id: A8MJW4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.

350688:CLOS RS00730
gene id: 350688:CLOS_RS00730
uniprot id: A8MFQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

350688:CLOS RS11310
gene id: 350688:CLOS_RS11310
uniprot id: A8MIS6
names: Similarity
messages: Belongs to the peptidase S16 family.

350688:CLOS RS03440
gene id: 350688:CLOS_RS03440
uniprot id: A8MM51
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M3B family.
messages: Binds 1 zinc ion.
messages: Has oligopeptidase activity and degrades a variety of small bioactive peptides.

350688:CLOS RS07985
gene id: 350688:CLOS_RS07985
uniprot id: A8MFD2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Monomer.

350688:CLOS RS01665
gene id: 350688:CLOS_RS01665
uniprot id: A8ML63
names: Similarity
messages: Belongs to the GerABKA family.

350688:CLOS RS07630
gene id: 350688:CLOS_RS07630
uniprot id: A8MHD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Cytoplasm

350688:CLOS RS12845
gene id: 350688:CLOS_RS12845
uniprot id: A8MJH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

350688:CLOS RS03275
gene id: 350688:CLOS_RS03275
uniprot id: A8MM19
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

350688:CLOS RS00925
gene id: 350688:CLOS_RS00925
uniprot id: A8MFU4
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase family.

350688:CLOS RS13020
gene id: 350688:CLOS_RS13020
uniprot id: A8MJK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

350688:CLOS RS05000
gene id: 350688:CLOS_RS05000
uniprot id: A8MFX8
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

350688:CLOS RS02255
gene id: 350688:CLOS_RS02255
uniprot id: A8MLT0
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

350688:CLOS RS14010
gene id: 350688:CLOS_RS14010
uniprot id: A8MK57
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ribonuclease M5 family.
messages: Cytoplasm
messages: Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step.

350688:CLOS RS12220
gene id: 350688:CLOS_RS12220
uniprot id: A8MJA1
names: Subcellular Location Annotation
messages: Membrane

350688:CLOS RS01930
gene id: 350688:CLOS_RS01930
uniprot id: A8MLL4
names: Similarity
messages: Belongs to the bacterial microcompartments protein family.

350688:CLOS RS13515
gene id: 350688:CLOS_RS13515
uniprot id: A8MJV8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

350688:CLOS RS14050
gene id: 350688:CLOS_RS14050
uniprot id: A8MK65
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

350688:CLOS RS04770
gene id: 350688:CLOS_RS04770
uniprot id: A8MEZ3
names: Similarity
messages: Belongs to the peptidase C40 family.

350688:CLOS RS10455
gene id: 350688:CLOS_RS10455
uniprot id: A8MIA8
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSP33 family.
messages: Cytoplasm
messages: Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.
messages: Under oxidizing conditions two disulfide bonds are formed involving the reactive cysteines. Under reducing conditions zinc is bound to the reactive cysteines and the protein is inactive.

350688:CLOS RS04875
gene id: 350688:CLOS_RS04875
uniprot id: A8MFV5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane

350688:CLOS RS07880
gene id: 350688:CLOS_RS07880
uniprot id: A8MFB1
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

350688:CLOS RS07140
gene id: 350688:CLOS_RS07140
uniprot id: A8MH41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sbp family.
messages: Cell membrane

350688:CLOS RS02005
gene id: 350688:CLOS_RS02005
uniprot id: A8MLM9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Cytoplasm
messages: Homodimer or homotetramer.

350688:CLOS RS01030
gene id: 350688:CLOS_RS01030
uniprot id: A8MKT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

350688:CLOS RS13185
gene id: 350688:CLOS_RS13185
uniprot id: A8MJP2
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

350688:CLOS RS07435
gene id: 350688:CLOS_RS07435
uniprot id: A8MHA0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

350688:CLOS RS00365
gene id: 350688:CLOS_RS00365
uniprot id: A8MEF6
names: Function
names: Similarity
messages: Belongs to the transglycosylase MltG family.
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

350688:CLOS RS04410
gene id: 350688:CLOS_RS04410
uniprot id: A8MES2
names: Similarity
messages: Belongs to the pirin family.

350688:CLOS RS13075
gene id: 350688:CLOS_RS13075
uniprot id: A8MJM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

350688:CLOS RS00980
gene id: 350688:CLOS_RS00980
uniprot id: A8MKS7
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.

350688:CLOS RS02590
gene id: 350688:CLOS_RS02590
uniprot id: A8MLE7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

350688:CLOS RS01100
gene id: 350688:CLOS_RS01100
uniprot id: A8MKV1
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

350688:CLOS RS10560
gene id: 350688:CLOS_RS10560
uniprot id: A8MIC9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

350688:CLOS RS12530
gene id: 350688:CLOS_RS12530
uniprot id: A8MJG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetokinase family.
messages: Cytoplasm

350688:CLOS RS02635
gene id: 350688:CLOS_RS02635
uniprot id: A8MLF6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

350688:CLOS RS02550
gene id: 350688:CLOS_RS02550
uniprot id: A8MLD9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

350688:CLOS RS04160
gene id: 350688:CLOS_RS04160
uniprot id: A8MEM6
names: Function
names: Similarity
messages: Belongs to the PduL family.
messages: Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate.

350688:CLOS RS10565
gene id: 350688:CLOS_RS10565
uniprot id: A8MID0
names: Function
names: Similarity
messages: Belongs to the alpha/beta-type SASP family.
messages: SASP are bound to spore DNA. They are double-stranded DNA-binding proteins that cause DNA to change to an a-like conformation. They protect the DNA backbone from chemical and enzymatic cleavage and are thus involved in dormant spore's high resistance to UV light.

350688:CLOS RS06450
gene id: 350688:CLOS_RS06450
uniprot id: A8MG67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Membrane

350688:CLOS RS14125
gene id: 350688:CLOS_RS14125
uniprot id: A8MK80
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

350688:CLOS RS02285
gene id: 350688:CLOS_RS02285
uniprot id: A8MLT6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OadG family.
messages: Catalyzes the decarboxylation of oxaloacetate coupled to Na(+) translocation.
messages: Cell membrane

350688:CLOS RS14855
gene id: 350688:CLOS_RS14855
uniprot id: A8MKM4
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

350688:CLOS RS05350
gene id: 350688:CLOS_RS05350
uniprot id: A8MG46
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

350688:CLOS RS03075
gene id: 350688:CLOS_RS03075
uniprot id: A8MLY1
names: Similarity
messages: Belongs to the pyruvate kinase family.
messages: In the C-terminal section; belongs to the PEP-utilizing enzyme family.

350688:CLOS RS02475
gene id: 350688:CLOS_RS02475
uniprot id: A8MLC4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

350688:CLOS RS07940
gene id: 350688:CLOS_RS07940
uniprot id: A8MFC3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase Y family.
messages: Cell membrane
messages: Endoribonuclease that initiates mRNA decay.

350688:CLOS RS01230
gene id: 350688:CLOS_RS01230
uniprot id: A8MKX6
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

350688:CLOS RS06970
gene id: 350688:CLOS_RS06970
uniprot id: A8MH07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

350688:CLOS RS08885
gene id: 350688:CLOS_RS08885
uniprot id: A8MHI9
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

350688:CLOS RS13955
gene id: 350688:CLOS_RS13955
uniprot id: A8MK46
names: Function
names: Similarity
messages: Belongs to the SpoVG family.
messages: Could be involved in septation.

350688:CLOS RS07555
gene id: 350688:CLOS_RS07555
uniprot id: A8MHC4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

350688:CLOS RS12290
gene id: 350688:CLOS_RS12290
uniprot id: A8MJB5
names: Subcellular Location Annotation
messages: Membrane

350688:CLOS RS02705
gene id: 350688:CLOS_RS02705
uniprot id: A8MLH0
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

350688:CLOS RS13520
gene id: 350688:CLOS_RS13520
uniprot id: A8MJV9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

350688:CLOS RS13915
gene id: 350688:CLOS_RS13915
uniprot id: A8MK38
names: Subcellular Location Annotation
messages: Membrane

350688:CLOS RS00540
gene id: 350688:CLOS_RS00540
uniprot id: A8MFM0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

350688:CLOS RS03335
gene id: 350688:CLOS_RS03335
uniprot id: A8MM31
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

350688:CLOS RS06410
gene id: 350688:CLOS_RS06410
uniprot id: A8MG59
names: Subcellular Location Annotation
messages: Membrane

350688:CLOS RS04460
gene id: 350688:CLOS_RS04460
uniprot id: A8MET2
names: Domain
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the CobB/CbiA family.
messages: Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source.
messages: Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP and cobyrinate and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.
messages: The a and c carboxylates of cobyrinate are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CbiA catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate.

350688:CLOS RS08280
gene id: 350688:CLOS_RS08280
uniprot id: A8MFJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

350688:CLOS RS10245
gene id: 350688:CLOS_RS10245
uniprot id: A8MI73
names: Similarity
messages: Belongs to the UPF0234 family.

350688:CLOS RS02820
gene id: 350688:CLOS_RS02820
uniprot id: A8MLJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

350688:CLOS RS07070
gene id: 350688:CLOS_RS07070
uniprot id: A8MH27
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

350688:CLOS RS06840
gene id: 350688:CLOS_RS06840
uniprot id: A8MGE1
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

350688:CLOS RS03605
gene id: 350688:CLOS_RS03605
uniprot id: A8MM84
names: Similarity
messages: Belongs to the iron-containing alcohol dehydrogenase family.

350688:CLOS RS11800
gene id: 350688:CLOS_RS11800
uniprot id: A8MJ19
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

350688:CLOS RS00720
gene id: 350688:CLOS_RS00720
uniprot id: A8MFQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

350688:CLOS RS04890
gene id: 350688:CLOS_RS04890
uniprot id: A8MFV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

350688:CLOS RS11750
gene id: 350688:CLOS_RS11750
uniprot id: A8MJ09
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

350688:CLOS RS12255
gene id: 350688:CLOS_RS12255
uniprot id: A8MJA8
names: Similarity
messages: Belongs to the UPF0045 family.

350688:CLOS RS08855
gene id: 350688:CLOS_RS08855
uniprot id: A8MHI4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

350688:CLOS RS07530
gene id: 350688:CLOS_RS07530
uniprot id: A8MHB9
names: Function
names: Similarity
messages: Belongs to the UPF0122 family.
messages: Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein.

350688:CLOS RS07690
gene id: 350688:CLOS_RS07690
uniprot id: A8MHF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliN/MopA/SpaO family.
messages: Membrane

350688:CLOS RS11320
gene id: 350688:CLOS_RS11320
uniprot id: A8MIS8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

350688:CLOS RS00515
gene id: 350688:CLOS_RS00515
uniprot id: A8MFL5
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

350688:CLOS RS13540
gene id: 350688:CLOS_RS13540
uniprot id: A8MJW3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.

350688:CLOS RS03880
gene id: 350688:CLOS_RS03880
uniprot id: A8MMD4
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

350688:CLOS RS10295
gene id: 350688:CLOS_RS10295
uniprot id: A8MI83
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

350688:CLOS RS08010
gene id: 350688:CLOS_RS08010
uniprot id: A8MFD7
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

350688:CLOS RS11325
gene id: 350688:CLOS_RS11325
uniprot id: A8MIS9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

350688:CLOS RS07180
gene id: 350688:CLOS_RS07180
uniprot id: A8MH49
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

350688:CLOS RS04575
gene id: 350688:CLOS_RS04575
uniprot id: A8MEV4
names: Similarity
messages: Belongs to the TPP enzyme family.

350688:CLOS RS06130
gene id: 350688:CLOS_RS06130
uniprot id: A8MF64
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAL/histidase family.
messages: Contains an active site 4-methylidene-imidazol-5-one (MIO), which is formed autocatalytically by cyclization and dehydration of residues Ala-Ser-Gly.
messages: Cytoplasm

350688:CLOS RS15350
gene id: 350688:CLOS_RS15350
uniprot id: A8MJP0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum
messages: Belongs to the FliD family.
messages: Homopentamer.
messages: Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Secreted

350688:CLOS RS13475
gene id: 350688:CLOS_RS13475
uniprot id: A8MJV0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

350688:CLOS RS07990
gene id: 350688:CLOS_RS07990
uniprot id: A8MFD3
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

350688:CLOS RS05695
gene id: 350688:CLOS_RS05695
uniprot id: A8MGV4
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

350688:CLOS RS02415
gene id: 350688:CLOS_RS02415
uniprot id: A8MLB2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).

350688:CLOS RS01280
gene id: 350688:CLOS_RS01280
uniprot id: A8MKY5
names: Similarity
messages: Belongs to the desulfoferrodoxin family.

350688:CLOS RS07865
gene id: 350688:CLOS_RS07865
uniprot id: A8MFA8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

350688:CLOS RS13970
gene id: 350688:CLOS_RS13970
uniprot id: A8MK49
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

350688:CLOS RS11280
gene id: 350688:CLOS_RS11280
uniprot id: A8MIS0
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

350688:CLOS RS13095
gene id: 350688:CLOS_RS13095
uniprot id: A8MJM4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic riboflavin transporter (P-RFT) (TC 2.A.87) family.
messages: Cell membrane
messages: Membrane
messages: Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex.

350688:CLOS RS04615
gene id: 350688:CLOS_RS04615
uniprot id: A8MEW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acyl-ACP thioesterase family.
messages: chloroplast

350688:CLOS RS02310
gene id: 350688:CLOS_RS02310
uniprot id: A8MLU1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

350688:CLOS RS07030
gene id: 350688:CLOS_RS07030
uniprot id: A8MH18
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

350688:CLOS RS02690
gene id: 350688:CLOS_RS02690
uniprot id: A8MLG7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

350688:CLOS RS08905
gene id: 350688:CLOS_RS08905
uniprot id: A8MHJ3
names: Function
messages: Translation factor necessary for the incorporation of selenocysteine into proteins. It probably replaces EF-Tu for the insertion of selenocysteine directed by the UGA codon. SelB binds GTP and GDP.

350688:CLOS RS13050
gene id: 350688:CLOS_RS13050
uniprot id: A8MJL4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transcriptional regulatory Rex family.
messages: Cytoplasm
messages: Homodimer.
messages: Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.

350688:CLOS RS03745
gene id: 350688:CLOS_RS03745
uniprot id: A8MMB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

350688:CLOS RS10525
gene id: 350688:CLOS_RS10525
uniprot id: A8MIC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Cytoplasm

350688:CLOS RS02760
gene id: 350688:CLOS_RS02760
uniprot id: A8MLI1
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

350688:CLOS RS05555
gene id: 350688:CLOS_RS05555
uniprot id: A8MGS8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LuxS family.
messages: Binds 1 Fe cation per subunit.
messages: Homodimer.
messages: Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).

350688:CLOS RS14425
gene id: 350688:CLOS_RS14425
uniprot id: A8MKD9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

350688:CLOS RS09105
gene id: 350688:CLOS_RS09105
uniprot id: A8MHN3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

350688:CLOS RS07455
gene id: 350688:CLOS_RS07455
uniprot id: A8MHA4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

350688:CLOS RS01765
gene id: 350688:CLOS_RS01765
uniprot id: A8ML82
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AP endonuclease 2 family.
messages: Binds 3 Zn(2+) ions.
messages: Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.

350688:CLOS RS08580
gene id: 350688:CLOS_RS08580
uniprot id: A8MGI7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
messages: Cytoplasm
messages: Homodimer. Forms a heterotetramer with IscU, interacts with other sulfur acceptors.
messages: Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.

350688:CLOS RS06175
gene id: 350688:CLOS_RS06175
uniprot id: A8MF74
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

350688:CLOS RS10310
gene id: 350688:CLOS_RS10310
uniprot id: A8MI86
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

350688:CLOS RS07800
gene id: 350688:CLOS_RS07800
uniprot id: A8MHH2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

350688:CLOS RS01150
gene id: 350688:CLOS_RS01150
uniprot id: A8MKW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

350688:CLOS RS07175
gene id: 350688:CLOS_RS07175
uniprot id: A8MH48
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

350688:CLOS RS13905
gene id: 350688:CLOS_RS13905
uniprot id: A8MK36
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

350688:CLOS RS11120
gene id: 350688:CLOS_RS11120
uniprot id: A8MIN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

350688:CLOS RS01365
gene id: 350688:CLOS_RS01365
uniprot id: A8ML02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

350688:CLOS RS12465
gene id: 350688:CLOS_RS12465
uniprot id: A8MJF0
names: Similarity
messages: Belongs to the bacterial microcompartments protein family.

350688:CLOS RS05190
gene id: 350688:CLOS_RS05190
uniprot id: A8MG16
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

350688:CLOS RS08945
gene id: 350688:CLOS_RS08945
uniprot id: A8MHK1
names: Similarity
messages: Belongs to the RutC family.

350688:CLOS RS08530
gene id: 350688:CLOS_RS08530
uniprot id: A8MGH7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

350688:CLOS RS07650
gene id: 350688:CLOS_RS07650
uniprot id: A8MHE3
names: Similarity
messages: Belongs to the FlgD family.

350688:CLOS RS04750
gene id: 350688:CLOS_RS04750
uniprot id: A8MEY9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

350688:CLOS RS11720
gene id: 350688:CLOS_RS11720
uniprot id: A8MJ03
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

350688:CLOS RS11130
gene id: 350688:CLOS_RS11130
uniprot id: A8MIP0
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

350688:CLOS RS08275
gene id: 350688:CLOS_RS08275
uniprot id: A8MFJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

350688:CLOS RS02080
gene id: 350688:CLOS_RS02080
uniprot id: A8MLP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0073 (Hly-III) family.
messages: Membrane

350688:CLOS RS08000
gene id: 350688:CLOS_RS08000
uniprot id: A8MFD5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

350688:CLOS RS03700
gene id: 350688:CLOS_RS03700
uniprot id: A8MMA3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

350688:CLOS RS07920
gene id: 350688:CLOS_RS07920
uniprot id: A8MFB9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Homohexamer. Forms a ring that surrounds DNA.
messages: Membrane

350688:CLOS RS07160
gene id: 350688:CLOS_RS07160
uniprot id: A8MH45
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

350688:CLOS RS06480
gene id: 350688:CLOS_RS06480
uniprot id: A8MG73
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm
messages: Homodimer.

350688:CLOS RS12535
gene id: 350688:CLOS_RS12535
uniprot id: A8MJG4
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

350688:CLOS RS05285
gene id: 350688:CLOS_RS05285
uniprot id: A8MG35
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

350688:CLOS RS03040
gene id: 350688:CLOS_RS03040
uniprot id: A8MLX4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urocanase family.
messages: Binds 1 NAD(+) per subunit.
messages: Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

350688:CLOS RS08190
gene id: 350688:CLOS_RS08190
uniprot id: A8MFH3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

350688:CLOS RS00990
gene id: 350688:CLOS_RS00990
uniprot id: A8MKS9
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

350688:CLOS RS06605
gene id: 350688:CLOS_RS06605
uniprot id: A8MG96
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

350688:CLOS RS15235
gene id: 350688:CLOS_RS15235
uniprot id: A8MF76
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

350688:CLOS RS08835
gene id: 350688:CLOS_RS08835
uniprot id: A8MGN9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

350688:CLOS RS08915
gene id: 350688:CLOS_RS08915
uniprot id: A8MHJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

350688:CLOS RS08730
gene id: 350688:CLOS_RS08730
uniprot id: A8MGL7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.

350688:CLOS RS02950
gene id: 350688:CLOS_RS02950
uniprot id: A8MLV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

350688:CLOS RS09295
gene id: 350688:CLOS_RS09295
uniprot id: A8MHS1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThiI family.
messages: Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
messages: Cytoplasm

350688:CLOS RS08930
gene id: 350688:CLOS_RS08930
uniprot id: A8MHJ8
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

350688:CLOS RS02235
gene id: 350688:CLOS_RS02235
uniprot id: A8MLS6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

350688:CLOS RS05465
gene id: 350688:CLOS_RS05465
uniprot id: A8MGR0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

350688:CLOS RS08020
gene id: 350688:CLOS_RS08020
uniprot id: A8MFD9
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

350688:CLOS RS13580
gene id: 350688:CLOS_RS13580
uniprot id: A8MJX1
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

350688:CLOS RS15940
gene id: 350688:CLOS_RS15940
uniprot id: A8MIS4
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

350688:CLOS RS14620
gene id: 350688:CLOS_RS14620
uniprot id: A8MKH8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

350688:CLOS RS01415
gene id: 350688:CLOS_RS01415
uniprot id: A8ML12
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PstS family.
messages: Cell membrane
messages: Involved in the system for phosphate transport across the cytoplasmic membrane.
messages: Membrane
messages: Part of the ABC transporter complex PstSACB involved in phosphate import.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

350688:CLOS RS05225
gene id: 350688:CLOS_RS05225
uniprot id: A8MG23
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane
messages: Part of an ABC transporter complex. Responsible for energy coupling to the transport system.

350688:CLOS RS05025
gene id: 350688:CLOS_RS05025
uniprot id: A8MFY3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

350688:CLOS RS00970
gene id: 350688:CLOS_RS00970
uniprot id: A8MKS5
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

350688:CLOS RS05270
gene id: 350688:CLOS_RS05270
uniprot id: A8MG32
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

350688:CLOS RS03860
gene id: 350688:CLOS_RS03860
uniprot id: A8MMD0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

350688:CLOS RS12380
gene id: 350688:CLOS_RS12380
uniprot id: A8MJD3
names: Function
names: Similarity
messages: Belongs to the SELO family.
messages: Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).

350688:CLOS RS14995
gene id: 350688:CLOS_RS14995
uniprot id: A8MKP8
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.

350688:CLOS RS02665
gene id: 350688:CLOS_RS02665
uniprot id: A8MLG2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

350688:CLOS RS07590
gene id: 350688:CLOS_RS07590
uniprot id: A8MHD1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

350688:CLOS RS02565
gene id: 350688:CLOS_RS02565
uniprot id: A8MLE2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

350688:CLOS RS05210
gene id: 350688:CLOS_RS05210
uniprot id: A8MG20
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CbiM family.
messages: Cell membrane
messages: Forms an energy-coupling factor (ECF) transporter complex composed of an ATP-binding protein (A component, CbiO), a transmembrane protein (T component, CbiQ) and 2 possible substrate-capture proteins (S components, CbiM and CbiN) of unknown stoichimetry.
messages: Membrane
messages: Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import.

350688:CLOS RS14420
gene id: 350688:CLOS_RS14420
uniprot id: A8MKD8
names: Subcellular Location Annotation
messages: Membrane

350688:CLOS RS03200
gene id: 350688:CLOS_RS03200
uniprot id: A8MM04
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

350688:CLOS RS05800
gene id: 350688:CLOS_RS05800
uniprot id: A8MGX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

350688:CLOS RS12835
gene id: 350688:CLOS_RS12835
uniprot id: A8MJH2
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.

350688:CLOS RS12365
gene id: 350688:CLOS_RS12365
uniprot id: A8MJD0
names: Similarity
messages: Belongs to the BMP lipoprotein family.

350688:CLOS RS01500
gene id: 350688:CLOS_RS01500
uniprot id: A8ML31
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

350688:CLOS RS14790
gene id: 350688:CLOS_RS14790
uniprot id: A8MKL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

350688:CLOS RS08535
gene id: 350688:CLOS_RS08535
uniprot id: A8MGH8
names: Similarity
messages: Belongs to the Fur family.

350688:CLOS RS02060
gene id: 350688:CLOS_RS02060
uniprot id: A8MLP0
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

350688:CLOS RS03640
gene id: 350688:CLOS_RS03640
uniprot id: A8MM91
names: Similarity
messages: Belongs to the CAPAB/TerDEXZ family.

350688:CLOS RS11315
gene id: 350688:CLOS_RS11315
uniprot id: A8MIS7
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

350688:CLOS RS06070
gene id: 350688:CLOS_RS06070
uniprot id: A8MF52
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.
messages: May be involved in the biosynthesis of molybdopterin.

350688:CLOS RS07170
gene id: 350688:CLOS_RS07170
uniprot id: A8MH47
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

350688:CLOS RS04735
gene id: 350688:CLOS_RS04735
uniprot id: A8MEY6
names: Similarity
messages: Belongs to the Fur family.

350688:CLOS RS14100
gene id: 350688:CLOS_RS14100
uniprot id: A8MK75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

350688:CLOS RS07145
gene id: 350688:CLOS_RS07145
uniprot id: A8MH42
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

350688:CLOS RS05755
gene id: 350688:CLOS_RS05755
uniprot id: A8MGW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Cell membrane
messages: Membrane

350688:CLOS RS10120
gene id: 350688:CLOS_RS10120
uniprot id: A8MI49
names: Similarity
messages: Belongs to the CinA family.

350688:CLOS RS02510
gene id: 350688:CLOS_RS02510
uniprot id: A8MLD1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

350688:CLOS RS08200
gene id: 350688:CLOS_RS08200
uniprot id: A8MFH5
names: Similarity
messages: Belongs to the Nudix hydrolase family.

350688:CLOS RS07490
gene id: 350688:CLOS_RS07490
uniprot id: A8MHB1
names: Similarity
messages: Belongs to the fabD family.

350688:CLOS RS09555
gene id: 350688:CLOS_RS09555
uniprot id: A8MHU4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
messages: Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
messages: Homodimer.

350688:CLOS RS13685
gene id: 350688:CLOS_RS13685
uniprot id: A8MJZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

350688:CLOS RS01180
gene id: 350688:CLOS_RS01180
uniprot id: A8MKW6
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

350688:CLOS RS06260
gene id: 350688:CLOS_RS06260
uniprot id: A8MF88
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

350688:CLOS RS10825
gene id: 350688:CLOS_RS10825
uniprot id: A8MII0
names: Function
names: Similarity
messages: Belongs to the alpha/beta-type SASP family.
messages: SASP are bound to spore DNA. They are double-stranded DNA-binding proteins that cause DNA to change to an a-like conformation. They protect the DNA backbone from chemical and enzymatic cleavage and are thus involved in dormant spore's high resistance to UV light.

350688:CLOS RS00350
gene id: 350688:CLOS_RS00350
uniprot id: A8MEF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

350688:CLOS RS02805
gene id: 350688:CLOS_RS02805
uniprot id: A8MLJ0
names: Similarity
messages: Belongs to the GARS family.

350688:CLOS RS04130
gene id: 350688:CLOS_RS04130
uniprot id: A8MEM0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial microcompartment
messages: Belongs to the EutC family.
messages: Binds between the large and small subunits.
messages: Catalyzes the deamination of various vicinal amino-alcohols to oxo compounds. Allows this organism to utilize ethanolamine as the sole source of nitrogen and carbon in the presence of external vitamin B12.
messages: The basic unit is a heterodimer which dimerizes to form tetramers. The heterotetramers trimerize; 6 large subunits form a core ring with 6 small subunits projecting outwards.

350688:CLOS RS07850
gene id: 350688:CLOS_RS07850
uniprot id: A8MHI1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

350688:CLOS RS00785
gene id: 350688:CLOS_RS00785
uniprot id: A8MFR8
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

350688:CLOS RS10210
gene id: 350688:CLOS_RS10210
uniprot id: A8MI66
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

350688:CLOS RS00430
gene id: 350688:CLOS_RS00430
uniprot id: A8MEG7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. C-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

350688:CLOS RS07475
gene id: 350688:CLOS_RS07475
uniprot id: A8MHA8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

350688:CLOS RS04305
gene id: 350688:CLOS_RS04305
uniprot id: A8MEQ1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

350688:CLOS RS11250
gene id: 350688:CLOS_RS11250
uniprot id: A8MIR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

350688:CLOS RS01825
gene id: 350688:CLOS_RS01825
uniprot id: A8ML94
names: Similarity
messages: Belongs to the peptidase S66 family.

350688:CLOS RS08155
gene id: 350688:CLOS_RS08155
uniprot id: A8MFG6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ScpB family.
messages: Cytoplasm
messages: Homodimer. Homodimerization may be required to stabilize the binding of ScpA to the Smc head domains. Component of a cohesin-like complex composed of ScpA, ScpB and the Smc homodimer, in which ScpA and ScpB bind to the head domain of Smc. The presence of the three proteins is required for the association of the complex with DNA.
messages: Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves.

350688:CLOS RS02595
gene id: 350688:CLOS_RS02595
uniprot id: A8MLE8
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

350688:CLOS RS08935
gene id: 350688:CLOS_RS08935
uniprot id: A8MHJ9
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

350688:CLOS RS10545
gene id: 350688:CLOS_RS10545
uniprot id: A8MIC6
names: Similarity
messages: Belongs to the ABC transporter superfamily.

350688:CLOS RS06490
gene id: 350688:CLOS_RS06490
uniprot id: A8MG75
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.

350688:CLOS RS15150
gene id: 350688:CLOS_RS15150
uniprot id: A8MFT7
names: Similarity
messages: Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family.

350688:CLOS RS07320
gene id: 350688:CLOS_RS07320
uniprot id: A8MH77
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.

350688:CLOS RS08910
gene id: 350688:CLOS_RS08910
uniprot id: A8MHJ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SelA family.
messages: Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
messages: Cytoplasm

350688:CLOS RS14460
gene id: 350688:CLOS_RS14460
uniprot id: A8MKE6
names: Similarity
messages: Belongs to the EamA transporter family.

350688:CLOS RS01375
gene id: 350688:CLOS_RS01375
uniprot id: A8ML04
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

350688:CLOS RS14155
gene id: 350688:CLOS_RS14155
uniprot id: A8MK86
names: Similarity
messages: Belongs to the organic radical-activating enzymes family.

350688:CLOS RS08015
gene id: 350688:CLOS_RS08015
uniprot id: A8MFD8
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

350688:CLOS RS02480
gene id: 350688:CLOS_RS02480
uniprot id: A8MLC5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

350688:CLOS RS04455
gene id: 350688:CLOS_RS04455
uniprot id: A8MET1
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

350688:CLOS RS11350
gene id: 350688:CLOS_RS11350
uniprot id: A8MIT5
names: Similarity
messages: Belongs to the carbamate kinase family.

350688:CLOS RS01895
gene id: 350688:CLOS_RS01895
uniprot id: A8MLA7
names: Subunit
messages: Homotetramer.

350688:CLOS RS11840
gene id: 350688:CLOS_RS11840
uniprot id: A8MJ27
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

350688:CLOS RS02840
gene id: 350688:CLOS_RS02840
uniprot id: A8MLJ5
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.

350688:CLOS RS11425
gene id: 350688:CLOS_RS11425
uniprot id: A8MIV0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

350688:CLOS RS12260
gene id: 350688:CLOS_RS12260
uniprot id: A8MJA9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase C15 family.
messages: Cytoplasm
messages: Homotetramer.
messages: Removes 5-oxoproline from various penultimate amino acid residues except L-proline.

350688:CLOS RS01215
gene id: 350688:CLOS_RS01215
uniprot id: A8MKX3
names: Cofactor
names: Similarity
messages: Belongs to the arginase family.
messages: Binds 2 manganese ions per subunit.

350688:CLOS RS03750
gene id: 350688:CLOS_RS03750
uniprot id: A8MMB3
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

350688:CLOS RS14135
gene id: 350688:CLOS_RS14135
uniprot id: A8MK82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

350688:CLOS RS11305
gene id: 350688:CLOS_RS11305
uniprot id: A8MIS5
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

350688:CLOS RS12450
gene id: 350688:CLOS_RS12450
uniprot id: A8MJE7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the organic radical-activating enzymes family.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes activation of the choline trimethylamine-lyase CutC under anaerobic conditions by generation of an organic free radical on a glycine residue, via an homolytic cleavage of S-adenosyl-L-methionine (SAM).

350688:CLOS RS13200
gene id: 350688:CLOS_RS13200
uniprot id: A8MJP5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin. Binds to flagellin and participates in the assembly of the flagellum.
messages: Belongs to the FliW family.
messages: Cytoplasm
messages: Interacts with translational regulator CsrA and flagellin(s).

350688:CLOS RS13620
gene id: 350688:CLOS_RS13620
uniprot id: A8MJX9
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

350688:CLOS RS07010
gene id: 350688:CLOS_RS07010
uniprot id: A8MH14
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

350688:CLOS RS09025
gene id: 350688:CLOS_RS09025
uniprot id: A8MHL7
names: Function
names: Similarity
messages: Belongs to the MinE family.
messages: Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.

350688:CLOS RS11540
gene id: 350688:CLOS_RS11540
uniprot id: A8MIX2
names: Function
names: Similarity
messages: Belongs to the flavodoxin family.
messages: Low-potential electron donor to a number of redox enzymes.

350688:CLOS RS00780
gene id: 350688:CLOS_RS00780
uniprot id: A8MFR7
names: Similarity
messages: In the N-terminal section; belongs to the zinc metallo-hydrolase group 3 family.

350688:CLOS RS02835
gene id: 350688:CLOS_RS02835
uniprot id: A8MLJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

350688:CLOS RS07400
gene id: 350688:CLOS_RS07400
uniprot id: A8MH93
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

350688:CLOS RS03520
gene id: 350688:CLOS_RS03520
uniprot id: A8MM67
names: Subcellular Location Annotation
messages: Membrane

350688:CLOS RS00360
gene id: 350688:CLOS_RS00360
uniprot id: A8MEF5
names: Similarity
messages: Belongs to the glycosyl hydrolase 39 family.

350688:CLOS RS07870
gene id: 350688:CLOS_RS07870
uniprot id: A8MFA9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

350688:CLOS RS13470
gene id: 350688:CLOS_RS13470
uniprot id: A8MJU9
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

350688:CLOS RS02645
gene id: 350688:CLOS_RS02645
uniprot id: A8MLF8
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

350688:CLOS RS13445
gene id: 350688:CLOS_RS13445
uniprot id: A8MJU4
names: Similarity
messages: Belongs to the four-carbon acid sugar kinase family.

350688:CLOS RS11910
gene id: 350688:CLOS_RS11910
uniprot id: A8MJ40
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

350688:CLOS RS05690
gene id: 350688:CLOS_RS05690
uniprot id: A8MGV3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

350688:CLOS RS07610
gene id: 350688:CLOS_RS07610
uniprot id: A8MHD5
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

350688:CLOS RS07355
gene id: 350688:CLOS_RS07355
uniprot id: A8MH84
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

350688:CLOS RS08640
gene id: 350688:CLOS_RS08640
uniprot id: A8MGJ9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

350688:CLOS RS03655
gene id: 350688:CLOS_RS03655
uniprot id: A8MM94
names: Similarity
messages: Belongs to the CAPAB/TerDEXZ family.

350688:CLOS RS08540
gene id: 350688:CLOS_RS08540
uniprot id: A8MGH9
names: Similarity
messages: Belongs to the UPF0473 family.

350688:CLOS RS03260
gene id: 350688:CLOS_RS03260
uniprot id: A8MM16
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

350688:CLOS RS05770
gene id: 350688:CLOS_RS05770
uniprot id: A8MGW9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

350688:CLOS RS05595
gene id: 350688:CLOS_RS05595
uniprot id: A8MGT5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

350688:CLOS RS14715
gene id: 350688:CLOS_RS14715
uniprot id: A8MKJ7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

350688:CLOS RS05005
gene id: 350688:CLOS_RS05005
uniprot id: A8MFX9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

350688:CLOS RS12350
gene id: 350688:CLOS_RS12350
uniprot id: A8MJC7
names: Subcellular Location Annotation
messages: Membrane

350688:CLOS RS10810
gene id: 350688:CLOS_RS10810
uniprot id: A8MIH7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

350688:CLOS RS02630
gene id: 350688:CLOS_RS02630
uniprot id: A8MLF5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

350688:CLOS RS10830
gene id: 350688:CLOS_RS10830
uniprot id: A8MII1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

350688:CLOS RS10185
gene id: 350688:CLOS_RS10185
uniprot id: A8MI61
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

350688:CLOS RS05660
gene id: 350688:CLOS_RS05660
uniprot id: A8MGU7
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

350688:CLOS RS09130
gene id: 350688:CLOS_RS09130
uniprot id: A8MHN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

350688:CLOS RS04300
gene id: 350688:CLOS_RS04300
uniprot id: A8MEQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

350688:CLOS RS06890
gene id: 350688:CLOS_RS06890
uniprot id: A8MGZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

350688:CLOS RS08900
gene id: 350688:CLOS_RS08900
uniprot id: A8MHJ2
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

350688:CLOS RS07045
gene id: 350688:CLOS_RS07045
uniprot id: A8MH21
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

350688:CLOS RS03705
gene id: 350688:CLOS_RS03705
uniprot id: A8MMA4
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

350688:CLOS RS00385
gene id: 350688:CLOS_RS00385
uniprot id: A8MEF8
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

350688:CLOS RS07135
gene id: 350688:CLOS_RS07135
uniprot id: A8MH40
names: Similarity
messages: Belongs to the UPF0749 family.

350688:CLOS RS15100
gene id: 350688:CLOS_RS15100
uniprot id: A8MKR9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.

350688:CLOS RS05275
gene id: 350688:CLOS_RS05275
uniprot id: A8MG33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

350688:CLOS RS00725
gene id: 350688:CLOS_RS00725
uniprot id: A8MFQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

350688:CLOS RS03305
gene id: 350688:CLOS_RS03305
uniprot id: A8MM25
names: Similarity
messages: Belongs to the ArsC family.

350688:CLOS RS07395
gene id: 350688:CLOS_RS07395
uniprot id: A8MH92
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

350688:CLOS RS04635
gene id: 350688:CLOS_RS04635
uniprot id: A8MEW6
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

350688:CLOS RS13635
gene id: 350688:CLOS_RS13635
uniprot id: A8MJY2
names: Subcellular Location Annotation
messages: Membrane

350688:CLOS RS04960
gene id: 350688:CLOS_RS04960
uniprot id: A8MFX0
names: Similarity
messages: Belongs to the BMP lipoprotein family.

350688:CLOS RS11015
gene id: 350688:CLOS_RS11015
uniprot id: A8MIL7
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

350688:CLOS RS14180
gene id: 350688:CLOS_RS14180
uniprot id: A8MK91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

350688:CLOS RS12315
gene id: 350688:CLOS_RS12315
uniprot id: A8MJC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

350688:CLOS RS06895
gene id: 350688:CLOS_RS06895
uniprot id: A8MGZ3
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

350688:CLOS RS04860
gene id: 350688:CLOS_RS04860
uniprot id: A8MF11
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

350688:CLOS RS02585
gene id: 350688:CLOS_RS02585
uniprot id: A8MLE6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

350688:CLOS RS08565
gene id: 350688:CLOS_RS08565
uniprot id: A8MGI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

350688:CLOS RS10540
gene id: 350688:CLOS_RS10540
uniprot id: A8MIC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

350688:CLOS RS13615
gene id: 350688:CLOS_RS13615
uniprot id: A8MJX8
names: Subcellular Location Annotation
messages: Membrane

350688:CLOS RS01435
gene id: 350688:CLOS_RS01435
uniprot id: A8ML16
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

350688:CLOS RS10165
gene id: 350688:CLOS_RS10165
uniprot id: A8MI56
names: Similarity
messages: In the N-terminal section; belongs to the zinc metallo-hydrolase group 3 family.

350688:CLOS RS00525
gene id: 350688:CLOS_RS00525
uniprot id: A8MFL7
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase family.

350688:CLOS RS03725
gene id: 350688:CLOS_RS03725
uniprot id: A8MMA8
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

350688:CLOS RS00020
gene id: 350688:CLOS_RS00020
uniprot id: A8MEA1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

350688:CLOS RS02905
gene id: 350688:CLOS_RS02905
uniprot id: A8MLK7
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

350688:CLOS RS08035
gene id: 350688:CLOS_RS08035
uniprot id: A8MFE2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

350688:CLOS RS11825
gene id: 350688:CLOS_RS11825
uniprot id: A8MJ24
names: Function
names: Similarity
messages: Belongs to the PemK/MazF family.
messages: Toxic component of a type II toxin-antitoxin (TA) system.

350688:CLOS RS01360
gene id: 350688:CLOS_RS01360
uniprot id: A8ML01
names: Subcellular Location Annotation
messages: Membrane

350688:CLOS RS07275
gene id: 350688:CLOS_RS07275
uniprot id: A8MH68
names: Subcellular Location Annotation
messages: Cytoplasm

350688:CLOS RS10985
gene id: 350688:CLOS_RS10985
uniprot id: A8MIL1
names: Function
names: Similarity
messages: Belongs to the peptidase S51 family.
messages: Exopeptidase that catalyzes the hydrolytic cleavage of multi-L-arginyl-poly-L-aspartic acid (cyanophycin; a water-insoluble reserve polymer) into aspartate-arginine dipeptides.

350688:CLOS RS06135
gene id: 350688:CLOS_RS06135
uniprot id: A8MF65
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. HutI family.
messages: Binds 1 zinc or iron ion per subunit.
messages: Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate. It is the third step in the universal histidine degradation pathway.
messages: Cytoplasm

350688:CLOS RS09095
gene id: 350688:CLOS_RS09095
uniprot id: A8MHN1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RnfG family.
messages: Cell membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

350688:CLOS RS11185
gene id: 350688:CLOS_RS11185
uniprot id: A8MIQ1
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

350688:CLOS RS05980
gene id: 350688:CLOS_RS05980
uniprot id: A8MF35
names: Similarity
messages: Belongs to the DNA glycosylase MPG family.

350688:CLOS RS01460
gene id: 350688:CLOS_RS01460
uniprot id: A8ML21
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

350688:CLOS RS14085
gene id: 350688:CLOS_RS14085
uniprot id: A8MK72
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. SigI subfamily.
messages: Cytoplasm
messages: Interacts with RsgI.
messages: Negatively regulated by the anti-sigma-I factor RsgI.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

350688:CLOS RS13525
gene id: 350688:CLOS_RS13525
uniprot id: A8MJW0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

350688:CLOS RS08960
gene id: 350688:CLOS_RS08960
uniprot id: A8MHK4
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

350688:CLOS RS07105
gene id: 350688:CLOS_RS07105
uniprot id: A8MH34
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

350688:CLOS RS08255
gene id: 350688:CLOS_RS08255
uniprot id: A8MFI6
names: Similarity
messages: Belongs to the TlyA family.

350688:CLOS RS00560
gene id: 350688:CLOS_RS00560
uniprot id: A8MFM4
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

350688:CLOS RS11775
gene id: 350688:CLOS_RS11775
uniprot id: A8MJ14
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

350688:CLOS RS07410
gene id: 350688:CLOS_RS07410
uniprot id: A8MH95
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

350688:CLOS RS13825
gene id: 350688:CLOS_RS13825
uniprot id: A8MK20
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.