34062:AXE82 RS05585
gene id: 34062:AXE82_RS05585
uniprot id: A0A378Q776
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

34062:AXE82 RS02950
gene id: 34062:AXE82_RS02950
uniprot id: A0A0X8K5I9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

34062:AXE82 RS06515
gene id: 34062:AXE82_RS06515
uniprot id: A0A378Q6K0
names: Similarity
messages: Belongs to the LOG family.

34062:AXE82 RS01245
gene id: 34062:AXE82_RS01245
uniprot id: A0A378Q9N4
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase family.

34062:AXE82 RS08295
gene id: 34062:AXE82_RS08295
uniprot id: A0A109WCD8
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.

34062:AXE82 RS02890
gene id: 34062:AXE82_RS02890
uniprot id: A0A378Q9P3
names: Similarity
messages: Belongs to the YkuD family.

34062:AXE82 RS00240
gene id: 34062:AXE82_RS00240
uniprot id: A0A120KQM7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Cytoplasm
messages: Oligomer of 12 subunits arranged in the form of two hexagons.

34062:AXE82 RS07225
gene id: 34062:AXE82_RS07225
uniprot id: A0A378Q623
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

34062:AXE82 RS01935
gene id: 34062:AXE82_RS01935
uniprot id: A0A378Q924
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

34062:AXE82 RS03405
gene id: 34062:AXE82_RS03405
uniprot id: A0A378Q8L8
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

34062:AXE82 RS07240
gene id: 34062:AXE82_RS07240
uniprot id: A0A0X8K6T8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

34062:AXE82 RS07340
gene id: 34062:AXE82_RS07340
uniprot id: A0A378QCA3
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

34062:AXE82 RS01615
gene id: 34062:AXE82_RS01615
uniprot id: A0A378QA57
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild-type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity.
messages: Belongs to the RecC family.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding.

34062:AXE82 RS09835
gene id: 34062:AXE82_RS09835
uniprot id: A0A120KR62
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

34062:AXE82 RS01825
gene id: 34062:AXE82_RS01825
uniprot id: A0A378QA93
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

34062:AXE82 RS04145
gene id: 34062:AXE82_RS04145
uniprot id: A0A0X8K5V3
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

34062:AXE82 RS00045
gene id: 34062:AXE82_RS00045
uniprot id: A0A378QA13
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

34062:AXE82 RS00160
gene id: 34062:AXE82_RS00160
uniprot id: A0A378QEM1
names: Similarity
messages: Belongs to the peptidase S16 family.

34062:AXE82 RS02395
gene id: 34062:AXE82_RS02395
uniprot id: A0A378Q969
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

34062:AXE82 RS01375
gene id: 34062:AXE82_RS01375
uniprot id: A0A378QAH6
names: Similarity
messages: Belongs to the GST superfamily.

34062:AXE82 RS07605
gene id: 34062:AXE82_RS07605
uniprot id: A0A378QGE2
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
messages: O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.

34062:AXE82 RS03525
gene id: 34062:AXE82_RS03525
uniprot id: A0A378Q824
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

34062:AXE82 RS04655
gene id: 34062:AXE82_RS04655
uniprot id: A0A0X8K871
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

34062:AXE82 RS10025
gene id: 34062:AXE82_RS10025
uniprot id: A0A378QCC3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane
messages: Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins.

34062:AXE82 RS08535
gene id: 34062:AXE82_RS08535
uniprot id: A0A378QB91
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Interacts with FtsZ.

34062:AXE82 RS05425
gene id: 34062:AXE82_RS05425
uniprot id: A0A109WBM1
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

34062:AXE82 RS08190
gene id: 34062:AXE82_RS08190
uniprot id: A0A0X8K7A1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

34062:AXE82 RS02695
gene id: 34062:AXE82_RS02695
uniprot id: A0A0X8K5A8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

34062:AXE82 RS07390
gene id: 34062:AXE82_RS07390
uniprot id: A0A378QC92
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

34062:AXE82 RS09805
gene id: 34062:AXE82_RS09805
uniprot id: A0A0X8K7U2
names: Subcellular Location Annotation
messages: Membrane

34062:AXE82 RS10640
gene id: 34062:AXE82_RS10640
uniprot id: A0A378QA53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

34062:AXE82 RS01180
gene id: 34062:AXE82_RS01180
uniprot id: A0A109WB55
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
messages: Cytoplasm
messages: Homodimer. Forms a heterotetramer with IscU, interacts with other sulfur acceptors.
messages: Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.

34062:AXE82 RS05665
gene id: 34062:AXE82_RS05665
uniprot id: A0A0X8K689
names: Similarity
messages: Belongs to the NAPRTase family.

34062:AXE82 RS00555
gene id: 34062:AXE82_RS00555
uniprot id: A0A378QED9
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

34062:AXE82 RS02590
gene id: 34062:AXE82_RS02590
uniprot id: A0A378Q940
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

34062:AXE82 RS11445
gene id: 34062:AXE82_RS11445
uniprot id: A0A378QVB3
names: Similarity
messages: Belongs to the UPF0053 family.

34062:AXE82 RS10645
gene id: 34062:AXE82_RS10645
uniprot id: A0A109WH79
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

34062:AXE82 RS04020
gene id: 34062:AXE82_RS04020
uniprot id: A0A109WCA2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

34062:AXE82 RS08645
gene id: 34062:AXE82_RS08645
uniprot id: A0A0X8K766
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

34062:AXE82 RS06315
gene id: 34062:AXE82_RS06315
uniprot id: A0A378Q7D9
names: Subcellular Location Annotation
messages: Membrane

34062:AXE82 RS07590
gene id: 34062:AXE82_RS07590
uniprot id: A0A378QBU0
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

34062:AXE82 RS03170
gene id: 34062:AXE82_RS03170
uniprot id: A0A378QCW8
names: Similarity
messages: Belongs to the peptidase S49 family.

34062:AXE82 RS02455
gene id: 34062:AXE82_RS02455
uniprot id: A0A0X8K838
names: Caution
names: Similarity
messages: Belongs to the Dps family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

34062:AXE82 RS10890
gene id: 34062:AXE82_RS10890
uniprot id: A0A120KRB2
names: Similarity
messages: Belongs to the site-specific recombinase resolvase family.

34062:AXE82 RS00585
gene id: 34062:AXE82_RS00585
uniprot id: A0A120KQP1
names: Similarity
messages: Belongs to the WrbA family.

34062:AXE82 RS07235
gene id: 34062:AXE82_RS07235
uniprot id: A0A378Q7T1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

34062:AXE82 RS04115
gene id: 34062:AXE82_RS04115
uniprot id: A0A378Q900
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

34062:AXE82 RS04625
gene id: 34062:AXE82_RS04625
uniprot id: A0A0X8K6D2
names: Function
names: Similarity
messages: Absolutely required for transposition of IS1.
messages: Belongs to the transposase 27 family.

34062:AXE82 RS10800
gene id: 34062:AXE82_RS10800
uniprot id: A0A378QAE4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

34062:AXE82 RS05095
gene id: 34062:AXE82_RS05095
uniprot id: A0A378Q7H8
names: Subcellular Location Annotation
messages: Membrane

34062:AXE82 RS09550
gene id: 34062:AXE82_RS09550
uniprot id: A0A0X8K7L3
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

34062:AXE82 RS02945
gene id: 34062:AXE82_RS02945
uniprot id: A0A0X8K5D0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

34062:AXE82 RS09875
gene id: 34062:AXE82_RS09875
uniprot id: A0A378QCF2
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

34062:AXE82 RS08385
gene id: 34062:AXE82_RS08385
uniprot id: A0A0X8K777
names: Function
messages: Member of the two-component regulatory system PhoR/PhoB involved in the phosphate regulon genes expression. PhoR may function as a membrane-associated protein kinase that phosphorylates PhoB in response to environmental signals.

34062:AXE82 RS01665
gene id: 34062:AXE82_RS01665
uniprot id: A0A378QA49
names: Similarity
messages: Belongs to the sulfate adenylyltransferase family.

34062:AXE82 RS09400
gene id: 34062:AXE82_RS09400
uniprot id: A0A378QBW0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

34062:AXE82 RS03475
gene id: 34062:AXE82_RS03475
uniprot id: A0A378Q835
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Catalyzes the last two steps in the biosynthesis of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the DAO family.
messages: In the N-terminal section; belongs to the methyltransferase superfamily. tRNA (mnm(5)s(2)U34)-methyltransferase family.

34062:AXE82 RS00985
gene id: 34062:AXE82_RS00985
uniprot id: A0A378Q9Y7
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

34062:AXE82 RS07995
gene id: 34062:AXE82_RS07995
uniprot id: A0A109WBX8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
messages: Cytoplasm
messages: Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
messages: Homodimer. UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

34062:AXE82 RS06915
gene id: 34062:AXE82_RS06915
uniprot id: A0A378Q6F3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

34062:AXE82 RS02200
gene id: 34062:AXE82_RS02200
uniprot id: A0A378QAL8
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. RsmD family.
messages: Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle.

34062:AXE82 RS08500
gene id: 34062:AXE82_RS08500
uniprot id: A0A378QBB1
names: Subcellular Location Annotation
messages: Membrane

34062:AXE82 RS00660
gene id: 34062:AXE82_RS00660
uniprot id: A0A378QBI8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di-trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

34062:AXE82 RS02895
gene id: 34062:AXE82_RS02895
uniprot id: A0A378Q8E5
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

34062:AXE82 RS04590
gene id: 34062:AXE82_RS04590
uniprot id: A0A378Q802
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

34062:AXE82 RS06795
gene id: 34062:AXE82_RS06795
uniprot id: A0A378Q7F1
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

34062:AXE82 RS09520
gene id: 34062:AXE82_RS09520
uniprot id: A0A0X8K7G1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

34062:AXE82 RS07595
gene id: 34062:AXE82_RS07595
uniprot id: A0A378QC51
names: Similarity
messages: Belongs to the phosphohexose mutase family.

34062:AXE82 RS05220
gene id: 34062:AXE82_RS05220
uniprot id: A0A0X8K8A3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

34062:AXE82 RS09815
gene id: 34062:AXE82_RS09815
uniprot id: A0A378QAZ0
names: Subcellular Location Annotation
messages: Membrane

34062:AXE82 RS07460
gene id: 34062:AXE82_RS07460
uniprot id: A0A378QCI0
names: Function
names: Similarity
messages: Belongs to the anhydro-N-acetylmuramic acid kinase family.
messages: Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.

34062:AXE82 RS07530
gene id: 34062:AXE82_RS07530
uniprot id: A0A378QCC2
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

34062:AXE82 RS02145
gene id: 34062:AXE82_RS02145
uniprot id: A0A378Q945
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

34062:AXE82 RS09795
gene id: 34062:AXE82_RS09795
uniprot id: A0A378QAL3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.
messages: Membrane
messages: Required for nicotinamide riboside transport across the inner membrane.

34062:AXE82 RS02940
gene id: 34062:AXE82_RS02940
uniprot id: A0A378Q8D4
names: Similarity
messages: Belongs to the UPF0246 family.

34062:AXE82 RS00940
gene id: 34062:AXE82_RS00940
uniprot id: A0A378Q9M7
names: Similarity
messages: Belongs to the PrpF family.

34062:AXE82 RS08085
gene id: 34062:AXE82_RS08085
uniprot id: A0A378QC18
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

34062:AXE82 RS04255
gene id: 34062:AXE82_RS04255
uniprot id: A0A109WGM8
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

34062:AXE82 RS01420
gene id: 34062:AXE82_RS01420
uniprot id: A0A378Q9T5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

34062:AXE82 RS07985
gene id: 34062:AXE82_RS07985
uniprot id: A0A378QC34
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UreE family.
messages: Cytoplasm
messages: Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly.

34062:AXE82 RS04465
gene id: 34062:AXE82_RS04465
uniprot id: A0A0X8K5Z7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LysR transcriptional regulatory family.
messages: Cytoplasm

34062:AXE82 RS09500
gene id: 34062:AXE82_RS09500
uniprot id: A0A378QFF0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

34062:AXE82 RS03885
gene id: 34062:AXE82_RS03885
uniprot id: A0A378Q7Y3
names: Similarity
messages: Belongs to the peptidase C40 family.

34062:AXE82 RS03455
gene id: 34062:AXE82_RS03455
uniprot id: A0A378QCR5
names: Similarity
messages: Belongs to the YciI family.

34062:AXE82 RS09405
gene id: 34062:AXE82_RS09405
uniprot id: A0A378QBE2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

34062:AXE82 RS06060
gene id: 34062:AXE82_RS06060
uniprot id: A0A378Q728
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NlpA lipoprotein family.
messages: Membrane

34062:AXE82 RS02560
gene id: 34062:AXE82_RS02560
uniprot id: A0A378Q8P9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

34062:AXE82 RS05200
gene id: 34062:AXE82_RS05200
uniprot id: A0A378Q775
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

34062:AXE82 RS03755
gene id: 34062:AXE82_RS03755
uniprot id: A0A378QCL1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.

34062:AXE82 RS05280
gene id: 34062:AXE82_RS05280
uniprot id: A0A0X8K673
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

34062:AXE82 RS08880
gene id: 34062:AXE82_RS08880
uniprot id: A0A378QB25
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

34062:AXE82 RS05260
gene id: 34062:AXE82_RS05260
uniprot id: A0A378Q8Y5
names: Function
names: Similarity
messages: Belongs to the DUF177 domain family.
messages: Plays a role in synthesis, processing and/or stability of 23S rRNA.

34062:AXE82 RS03875
gene id: 34062:AXE82_RS03875
uniprot id: A0A378Q8D2
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruD family.
messages: Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.

34062:AXE82 RS01640
gene id: 34062:AXE82_RS01640
uniprot id: A0A378Q984
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

34062:AXE82 RS09940
gene id: 34062:AXE82_RS09940
uniprot id: A0A109WC51
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

34062:AXE82 RS01205
gene id: 34062:AXE82_RS01205
uniprot id: A0A0X8K4U9
names: Similarity
messages: Belongs to the adrenodoxin/putidaredoxin family.

34062:AXE82 RS07555
gene id: 34062:AXE82_RS07555
uniprot id: A0A378QGF0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

34062:AXE82 RS03625
gene id: 34062:AXE82_RS03625
uniprot id: A0A378Q812
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

34062:AXE82 RS11290
gene id: 34062:AXE82_RS11290
uniprot id: A0A378QVI2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

34062:AXE82 RS09275
gene id: 34062:AXE82_RS09275
uniprot id: A0A0X8K7M9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

34062:AXE82 RS08040
gene id: 34062:AXE82_RS08040
uniprot id: A0A0X8K6Z3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

34062:AXE82 RS06955
gene id: 34062:AXE82_RS06955
uniprot id: A0A0X8K6Q3
names: Subcellular Location Annotation
messages: Membrane

34062:AXE82 RS00980
gene id: 34062:AXE82_RS00980
uniprot id: A0A0X8K4Q9
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

34062:AXE82 RS08080
gene id: 34062:AXE82_RS08080
uniprot id: A0A109WBY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

34062:AXE82 RS09395
gene id: 34062:AXE82_RS09395
uniprot id: A0A378QFG5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

34062:AXE82 RS08370
gene id: 34062:AXE82_RS08370
uniprot id: A0A378QCG3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

34062:AXE82 RS08740
gene id: 34062:AXE82_RS08740
uniprot id: A0A378QBN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0187 family.
messages: Membrane

34062:AXE82 RS08695
gene id: 34062:AXE82_RS08695
uniprot id: A0A378QB92
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

34062:AXE82 RS11765
gene id: 34062:AXE82_RS11765
uniprot id: A0A378QVJ7
names: Similarity
messages: Belongs to the IucA/IucC family.

34062:AXE82 RS02195
gene id: 34062:AXE82_RS02195
uniprot id: A0A378Q930
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transpeptidase family. MrdA subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall.
messages: Cell inner membrane

34062:AXE82 RS04350
gene id: 34062:AXE82_RS04350
uniprot id: A0A0X8K5U0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

34062:AXE82 RS11050
gene id: 34062:AXE82_RS11050
uniprot id: A0A378QV86
names: Similarity
messages: Belongs to the ParB family.

34062:AXE82 RS09885
gene id: 34062:AXE82_RS09885
uniprot id: A0A378QBL7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. UvrD subfamily.
messages: Homodimer.
messages: Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replication; it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction.

34062:AXE82 RS06410
gene id: 34062:AXE82_RS06410
uniprot id: A0A0X8K836
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

34062:AXE82 RS06440
gene id: 34062:AXE82_RS06440
uniprot id: A0A109WBR0
names: Similarity
messages: Belongs to the GbsR family.

34062:AXE82 RS03925
gene id: 34062:AXE82_RS03925
uniprot id: A0A378Q8C1
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

34062:AXE82 RS04765
gene id: 34062:AXE82_RS04765
uniprot id: A0A378QC17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein SsuA/TauA family.
messages: Periplasm

34062:AXE82 RS08835
gene id: 34062:AXE82_RS08835
uniprot id: A0A378QBL9
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

34062:AXE82 RS08335
gene id: 34062:AXE82_RS08335
uniprot id: A0A378QBD5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

34062:AXE82 RS06265
gene id: 34062:AXE82_RS06265
uniprot id: A0A378Q7F0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

34062:AXE82 RS06275
gene id: 34062:AXE82_RS06275
uniprot id: A0A0X8K6V7
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

34062:AXE82 RS03500
gene id: 34062:AXE82_RS03500
uniprot id: A0A0X8K823
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

34062:AXE82 RS11620
gene id: 34062:AXE82_RS11620
uniprot id: A0A378QVX2
names: Similarity
messages: Belongs to the HsdR family.

34062:AXE82 RS04780
gene id: 34062:AXE82_RS04780
uniprot id: A0A378Q8L7
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

34062:AXE82 RS00665
gene id: 34062:AXE82_RS00665
uniprot id: A0A109WB34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

34062:AXE82 RS10790
gene id: 34062:AXE82_RS10790
uniprot id: A0A378QA58
names: Function
names: Similarity
messages: Belongs to the trehalose phosphatase family.
messages: Removes the phosphate from trehalose 6-phosphate to produce free trehalose.

34062:AXE82 RS07700
gene id: 34062:AXE82_RS07700
uniprot id: A0A0X8K702
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

34062:AXE82 RS10400
gene id: 34062:AXE82_RS10400
uniprot id: A0A378QAR7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

34062:AXE82 RS11105
gene id: 34062:AXE82_RS11105
uniprot id: A0A378QV95
names: Subunit
messages: Homodimer.

34062:AXE82 RS11195
gene id: 34062:AXE82_RS11195
uniprot id: A0A0X8K8L8
names: Function
names: Similarity
messages: Belongs to the RutC family.
messages: Involved in pyrimidine catabolism. Catalyzes the deamination of 3-aminoacrylate to malonic semialdehyde, a reaction that can also occur spontaneously. RutC may facilitate the reaction and modulate the metabolic fitness, rather than catalyzing essential functions.

34062:AXE82 RS06995
gene id: 34062:AXE82_RS06995
uniprot id: A0A378Q6I8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

34062:AXE82 RS07075
gene id: 34062:AXE82_RS07075
uniprot id: A0A0X8K6R4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

34062:AXE82 RS00765
gene id: 34062:AXE82_RS00765
uniprot id: A0A378QEA1
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

34062:AXE82 RS06140
gene id: 34062:AXE82_RS06140
uniprot id: A0A0X8K835
names: Caution
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
messages: Part of the 50S ribosomal subunit.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

34062:AXE82 RS03015
gene id: 34062:AXE82_RS03015
uniprot id: A0A378QCZ5
names: Subcellular Location Annotation
messages: Membrane

34062:AXE82 RS10225
gene id: 34062:AXE82_RS10225
uniprot id: A0A378QC83
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

34062:AXE82 RS08720
gene id: 34062:AXE82_RS08720
uniprot id: A0A378QC90
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

34062:AXE82 RS06220
gene id: 34062:AXE82_RS06220
uniprot id: A0A378Q6I1
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

34062:AXE82 RS08485
gene id: 34062:AXE82_RS08485
uniprot id: A0A378QB97
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

34062:AXE82 RS00310
gene id: 34062:AXE82_RS00310
uniprot id: A0A0X8K4G8
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

34062:AXE82 RS02220
gene id: 34062:AXE82_RS02220
uniprot id: A0A378QA19
names: Subcellular Location Annotation
messages: Membrane

34062:AXE82 RS07670
gene id: 34062:AXE82_RS07670
uniprot id: A0A0X8K723
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

34062:AXE82 RS08395
gene id: 34062:AXE82_RS08395
uniprot id: A0A378QBE7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

34062:AXE82 RS02515
gene id: 34062:AXE82_RS02515
uniprot id: A0A378QAG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell inner membrane
messages: Membrane

34062:AXE82 RS10115
gene id: 34062:AXE82_RS10115
uniprot id: A0A378QAE8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

34062:AXE82 RS03275
gene id: 34062:AXE82_RS03275
uniprot id: A0A378QA05
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

34062:AXE82 RS03860
gene id: 34062:AXE82_RS03860
uniprot id: A0A0X8K808
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

34062:AXE82 RS01435
gene id: 34062:AXE82_RS01435
uniprot id: A0A378Q9Q4
names: Function
names: Similarity
messages: Belongs to the LpxK family.
messages: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

34062:AXE82 RS05255
gene id: 34062:AXE82_RS05255
uniprot id: A0A120KQX5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

34062:AXE82 RS08540
gene id: 34062:AXE82_RS08540
uniprot id: A0A378QBT1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

34062:AXE82 RS05605
gene id: 34062:AXE82_RS05605
uniprot id: A0A120KQY7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

34062:AXE82 RS11190
gene id: 34062:AXE82_RS11190
uniprot id: A0A0X8K8H7
names: Function
names: Similarity
messages: Belongs to the non-flavoprotein flavin reductase family. RutF subfamily.
messages: Catalyzes the reduction of FMN to FMNH2 which is used to reduce pyrimidine by RutA via the Rut pathway.

34062:AXE82 RS06810
gene id: 34062:AXE82_RS06810
uniprot id: A0A378Q6D5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0060 family.
messages: Cell membrane

34062:AXE82 RS03585
gene id: 34062:AXE82_RS03585
uniprot id: A0A378Q855
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phospholipase A1 family.
messages: Binds 1 Ca(2+) ion per monomer. In the dimeric form the Ca(2+) is bound by different amino acids with binding of each Ca(2+) shared with ligands coming from each monomer. The Ca(2+) ion may have a role in catalysis.
messages: Cell outer membrane
messages: Homodimer; dimerization is reversible, and the dimeric form is the active one.
messages: Hydrolysis of phosphatidylcholine with phospholipase A2 (EC 3.1.1.4) and phospholipase A1 (EC 3.1.1.32) activities.
messages: Membrane

34062:AXE82 RS05620
gene id: 34062:AXE82_RS05620
uniprot id: A0A378Q7C6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

34062:AXE82 RS01800
gene id: 34062:AXE82_RS01800
uniprot id: A0A378Q9C2
names: Function
names: Similarity
messages: Belongs to the Dus family. DusB subfamily.
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

34062:AXE82 RS01845
gene id: 34062:AXE82_RS01845
uniprot id: A0A120KQR8
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

34062:AXE82 RS05515
gene id: 34062:AXE82_RS05515
uniprot id: A0A109WBM6
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

34062:AXE82 RS06960
gene id: 34062:AXE82_RS06960
uniprot id: A0A0X8K8J1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Cytoplasm
messages: Homodimer.

34062:AXE82 RS09185
gene id: 34062:AXE82_RS09185
uniprot id: A0A378QBA0
names: Subcellular Location Annotation
messages: Membrane

34062:AXE82 RS01440
gene id: 34062:AXE82_RS01440
uniprot id: A0A378Q9C4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

34062:AXE82 RS11120
gene id: 34062:AXE82_RS11120
uniprot id: A0A378QVF8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.
messages: Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU).
messages: Homotetramer.

34062:AXE82 RS02325
gene id: 34062:AXE82_RS02325
uniprot id: A0A378Q9P7
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.

34062:AXE82 RS05365
gene id: 34062:AXE82_RS05365
uniprot id: A0A378QBN6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SNF2/RAD54 helicase family. RapA subfamily.
messages: Interacts with the RNAP. Has a higher affinity for the core RNAP than for the holoenzyme. Its ATPase activity is stimulated by binding to RNAP.
messages: Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair.

34062:AXE82 RS09590
gene id: 34062:AXE82_RS09590
uniprot id: A0A378QAQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.
messages: Membrane

34062:AXE82 RS02380
gene id: 34062:AXE82_RS02380
uniprot id: A0A378Q986
names: Subcellular Location Annotation
messages: Membrane

34062:AXE82 RS06080
gene id: 34062:AXE82_RS06080
uniprot id: A0A0X8K6F6
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

34062:AXE82 RS10450
gene id: 34062:AXE82_RS10450
uniprot id: A0A109WC87
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

34062:AXE82 RS05900
gene id: 34062:AXE82_RS05900
uniprot id: A0A378QBE0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

34062:AXE82 RS00140
gene id: 34062:AXE82_RS00140
uniprot id: A0A378Q9Z3
names: Similarity
messages: Belongs to the peptidase M16 family.

34062:AXE82 RS11555
gene id: 34062:AXE82_RS11555
uniprot id: A0A378QVR8
names: Subcellular Location Annotation
messages: Membrane

34062:AXE82 RS07510
gene id: 34062:AXE82_RS07510
uniprot id: A0A378QCY4
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

34062:AXE82 RS09580
gene id: 34062:AXE82_RS09580
uniprot id: A0A378QB69
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

34062:AXE82 RS10190
gene id: 34062:AXE82_RS10190
uniprot id: A0A378QAZ8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b family.
messages: Binds 2 heme groups non-covalently.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

34062:AXE82 RS03840
gene id: 34062:AXE82_RS03840
uniprot id: A0A378Q7Z3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane

34062:AXE82 RS00770
gene id: 34062:AXE82_RS00770
uniprot id: A0A378QAN8
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

34062:AXE82 RS11455
gene id: 34062:AXE82_RS11455
uniprot id: A0A378QVM4
names: Similarity
messages: Belongs to the RelB/DinJ antitoxin family.

34062:AXE82 RS07470
gene id: 34062:AXE82_RS07470
uniprot id: A0A0X8K6V1
names: Similarity
messages: Belongs to the RelB/DinJ antitoxin family.

34062:AXE82 RS01810
gene id: 34062:AXE82_RS01810
uniprot id: A0A378QDM7
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.

34062:AXE82 RS03680
gene id: 34062:AXE82_RS03680
uniprot id: A0A0X8K5R6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

34062:AXE82 RS05685
gene id: 34062:AXE82_RS05685
uniprot id: A0A378Q762
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP E family.
messages: Cytoplasm

34062:AXE82 RS01860
gene id: 34062:AXE82_RS01860
uniprot id: A0A378QDL8
names: Similarity
messages: Belongs to the tRNA methyltransferase O family.

34062:AXE82 RS08120
gene id: 34062:AXE82_RS08120
uniprot id: A0A378QCR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm
messages: In the N-terminal section; belongs to the lyase 1 family. Argininosuccinate lyase subfamily.

34062:AXE82 RS06260
gene id: 34062:AXE82_RS06260
uniprot id: A0A378QB61
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

34062:AXE82 RS01415
gene id: 34062:AXE82_RS01415
uniprot id: A0A378QAA4
names: Function
names: Similarity
messages: Belongs to the ParB family.
messages: Involved in chromosome partition. Localize to both poles of the predivisional cell following completion of DNA replication. Binds to the DNA origin of replication.

34062:AXE82 RS01195
gene id: 34062:AXE82_RS01195
uniprot id: A0A378Q9P4
names: Function
messages: Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA.

34062:AXE82 RS01085
gene id: 34062:AXE82_RS01085
uniprot id: A0A0X8K4Q4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbB/TolQ family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

34062:AXE82 RS01775
gene id: 34062:AXE82_RS01775
uniprot id: A0A378QA99
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RlmKL family.
messages: Cytoplasm
messages: Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA.

34062:AXE82 RS11570
gene id: 34062:AXE82_RS11570
uniprot id: A0A378QVZ0
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

34062:AXE82 RS09895
gene id: 34062:AXE82_RS09895
uniprot id: A0A378QBT9
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

34062:AXE82 RS04260
gene id: 34062:AXE82_RS04260
uniprot id: A0A120KQW0
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

34062:AXE82 RS04165
gene id: 34062:AXE82_RS04165
uniprot id: A0A378Q894
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

34062:AXE82 RS05415
gene id: 34062:AXE82_RS05415
uniprot id: A0A0X8K6A2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

34062:AXE82 RS01965
gene id: 34062:AXE82_RS01965
uniprot id: A0A0X8K544
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

34062:AXE82 RS00760
gene id: 34062:AXE82_RS00760
uniprot id: A0A109WB42
names: Subcellular Location Annotation
messages: Cytoplasm

34062:AXE82 RS07220
gene id: 34062:AXE82_RS07220
uniprot id: A0A0X8K845
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

34062:AXE82 RS06055
gene id: 34062:AXE82_RS06055
uniprot id: A0A378Q7I5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

34062:AXE82 RS07655
gene id: 34062:AXE82_RS07655
uniprot id: A0A378QGD2
names: Similarity
messages: Belongs to the peptidase M16 family.

34062:AXE82 RS03530
gene id: 34062:AXE82_RS03530
uniprot id: A0A378Q8J9
names: Subcellular Location Annotation
messages: Membrane

34062:AXE82 RS00750
gene id: 34062:AXE82_RS00750
uniprot id: A0A378Q9M4
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

34062:AXE82 RS00685
gene id: 34062:AXE82_RS00685
uniprot id: A0A109WC93
names: Similarity
messages: Belongs to the Skp family.

34062:AXE82 RS02420
gene id: 34062:AXE82_RS02420
uniprot id: A0A378QDB0
names: Similarity
messages: Belongs to the citrate synthase family.

34062:AXE82 RS01100
gene id: 34062:AXE82_RS01100
uniprot id: A0A378QB98
names: Subcellular Location Annotation
messages: Periplasm

34062:AXE82 RS02310
gene id: 34062:AXE82_RS02310
uniprot id: A0A120KQR7
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GSP I family.
messages: Cell inner membrane
messages: Cleaved by prepilin peptidase.
messages: Component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.
messages: Membrane
messages: Type II secretion is composed of four main components: the outer membrane complex, the inner membrane complex, the cytoplasmic secretion ATPase and the periplasm-spanning pseudopilus.

34062:AXE82 RS10005
gene id: 34062:AXE82_RS10005
uniprot id: A0A109WC47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

34062:AXE82 RS11755
gene id: 34062:AXE82_RS11755
uniprot id: A0A378QXC9
names: Similarity
messages: Belongs to the IucA/IucC family.

34062:AXE82 RS01120
gene id: 34062:AXE82_RS01120
uniprot id: A0A378QAM3
names: Subcellular Location Annotation
messages: Membrane

34062:AXE82 RS10355
gene id: 34062:AXE82_RS10355
uniprot id: A0A378QAS5
names: Function
names: Similarity
messages: Belongs to the ABC transporter superfamily. Outer membrane lipopolysaccharide export (TC 1.B.42) family.
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane. Probably responsible for energy coupling to the transport system.

34062:AXE82 RS02550
gene id: 34062:AXE82_RS02550
uniprot id: A0A378Q8L1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Pal lipoprotein family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

34062:AXE82 RS05450
gene id: 34062:AXE82_RS05450
uniprot id: A0A378Q7W7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

34062:AXE82 RS08415
gene id: 34062:AXE82_RS08415
uniprot id: A0A120KR28
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

34062:AXE82 RS00020
gene id: 34062:AXE82_RS00020
uniprot id: A0A378QAM4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

34062:AXE82 RS10615
gene id: 34062:AXE82_RS10615
uniprot id: A0A378QB85
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

34062:AXE82 RS08035
gene id: 34062:AXE82_RS08035
uniprot id: A0A378QC26
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

34062:AXE82 RS04475
gene id: 34062:AXE82_RS04475
uniprot id: A0A378Q7K1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. Thiolase family.
messages: Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.
messages: Cytoplasm
messages: Heterotetramer of two alpha chains (FadB) and two beta chains (FadA).

34062:AXE82 RS06885
gene id: 34062:AXE82_RS06885
uniprot id: A0A378Q6M6
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

34062:AXE82 RS03600
gene id: 34062:AXE82_RS03600
uniprot id: A0A378Q9U2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbD subfamily.
messages: Cell inner membrane
messages: Membrane

34062:AXE82 RS10325
gene id: 34062:AXE82_RS10325
uniprot id: A0A378QC63
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

34062:AXE82 RS00690
gene id: 34062:AXE82_RS00690
uniprot id: A0A378QA50
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

34062:AXE82 RS09365
gene id: 34062:AXE82_RS09365
uniprot id: A0A378QAT3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COQ7 family.
messages: Binds 2 iron ions per subunit.
messages: Catalyzes the hydroxylation of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol during ubiquinone biosynthesis.
messages: Cell membrane

34062:AXE82 RS01360
gene id: 34062:AXE82_RS01360
uniprot id: A0A109WB68
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RlmJ family.
messages: Monomer.
messages: Specifically methylates the adenine in position 2030 of 23S rRNA.

34062:AXE82 RS10460
gene id: 34062:AXE82_RS10460
uniprot id: A0A378QA85
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

34062:AXE82 RS04505
gene id: 34062:AXE82_RS04505
uniprot id: A0A0X8K5V7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

34062:AXE82 RS04035
gene id: 34062:AXE82_RS04035
uniprot id: A0A0X8K5T3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

34062:AXE82 RS10310
gene id: 34062:AXE82_RS10310
uniprot id: A0A0X8K7T7
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.

34062:AXE82 RS08390
gene id: 34062:AXE82_RS08390
uniprot id: A0A0X8K756
names: Function
messages: This protein is a positive regulator for the phosphate regulon. Transcription of this operon is positively regulated by PhoB and PhoR when phosphate is limited.

34062:AXE82 RS07535
gene id: 34062:AXE82_RS07535
uniprot id: A0A378QBW6
names: Activity Regulation
names: Caution
names: Domain
names: Function
names: Similarity
messages: Belongs to the GlnD family.
messages: Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism.
messages: Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity.

34062:AXE82 RS04445
gene id: 34062:AXE82_RS04445
uniprot id: A0A378Q7W3
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

34062:AXE82 RS03100
gene id: 34062:AXE82_RS03100
uniprot id: A0A120KQT2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

34062:AXE82 RS00165
gene id: 34062:AXE82_RS00165
uniprot id: A0A378QB03
names: Similarity
messages: Belongs to the FGGY kinase family.

34062:AXE82 RS09840
gene id: 34062:AXE82_RS09840
uniprot id: A0A378QBU5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

34062:AXE82 RS04345
gene id: 34062:AXE82_RS04345
uniprot id: A0A109WBI7
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

34062:AXE82 RS02160
gene id: 34062:AXE82_RS02160
uniprot id: A0A0X8K527
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

34062:AXE82 RS10200
gene id: 34062:AXE82_RS10200
uniprot id: A0A109WC59
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

34062:AXE82 RS03815
gene id: 34062:AXE82_RS03815
uniprot id: A0A378Q8F8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

34062:AXE82 RS08300
gene id: 34062:AXE82_RS08300
uniprot id: A0A378QBE8
names: Caution
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

34062:AXE82 RS05060
gene id: 34062:AXE82_RS05060
uniprot id: A0A378Q840
names: Similarity
messages: Belongs to the TelA family.

34062:AXE82 RS10180
gene id: 34062:AXE82_RS10180
uniprot id: A0A378QF29
names: Similarity
messages: Belongs to the GST superfamily.

34062:AXE82 RS05855
gene id: 34062:AXE82_RS05855
uniprot id: A0A0X8K8A7
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

34062:AXE82 RS05050
gene id: 34062:AXE82_RS05050
uniprot id: A0A378Q922
names: Similarity
messages: Belongs to the radical SAM superfamily. KamA family.

34062:AXE82 RS01835
gene id: 34062:AXE82_RS01835
uniprot id: A0A378Q9H3
names: Similarity
messages: Belongs to the YfgM family.

34062:AXE82 RS03060
gene id: 34062:AXE82_RS03060
uniprot id: A0A0X8K5V6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Homodimer.

34062:AXE82 RS02725
gene id: 34062:AXE82_RS02725
uniprot id: A0A378Q9G4
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

34062:AXE82 RS00650
gene id: 34062:AXE82_RS00650
uniprot id: A0A0X8K536
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

34062:AXE82 RS05560
gene id: 34062:AXE82_RS05560
uniprot id: A0A378Q848
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

34062:AXE82 RS00305
gene id: 34062:AXE82_RS00305
uniprot id: A0A378QA76
names: Function
names: Similarity
messages: Belongs to the GlnE family.
messages: Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell.

34062:AXE82 RS08630
gene id: 34062:AXE82_RS08630
uniprot id: A0A378QCG4
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

34062:AXE82 RS06490
gene id: 34062:AXE82_RS06490
uniprot id: A0A378Q7A8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

34062:AXE82 RS00695
gene id: 34062:AXE82_RS00695
uniprot id: A0A378Q9T3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

34062:AXE82 RS06350
gene id: 34062:AXE82_RS06350
uniprot id: A0A378Q6R5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

34062:AXE82 RS07480
gene id: 34062:AXE82_RS07480
uniprot id: A0A378QBX9
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

34062:AXE82 RS03605
gene id: 34062:AXE82_RS03605
uniprot id: A0A0X8K5I2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP G family.
messages: Cell inner membrane
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

34062:AXE82 RS04315
gene id: 34062:AXE82_RS04315
uniprot id: A0A0X8K5V2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

34062:AXE82 RS00280
gene id: 34062:AXE82_RS00280
uniprot id: A0A0X8K4H7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

34062:AXE82 RS02225
gene id: 34062:AXE82_RS02225
uniprot id: A0A378Q8S5
names: Subcellular Location Annotation
messages: Cell outer membrane

34062:AXE82 RS02375
gene id: 34062:AXE82_RS02375
uniprot id: A0A378Q9N6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

34062:AXE82 RS06475
gene id: 34062:AXE82_RS06475
uniprot id: A0A378Q6P4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.

34062:AXE82 RS02295
gene id: 34062:AXE82_RS02295
uniprot id: A0A378Q985
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

34062:AXE82 RS08260
gene id: 34062:AXE82_RS08260
uniprot id: A0A378QBS4
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

34062:AXE82 RS01185
gene id: 34062:AXE82_RS01185
uniprot id: A0A378Q9H6
names: Function
names: Similarity
messages: A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.
messages: Belongs to the NifU family.

34062:AXE82 RS10010
gene id: 34062:AXE82_RS10010
uniprot id: A0A378QAL0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

34062:AXE82 RS08275
gene id: 34062:AXE82_RS08275
uniprot id: A0A378QCI7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

34062:AXE82 RS02800
gene id: 34062:AXE82_RS02800
uniprot id: A0A0X8K5S5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

34062:AXE82 RS03650
gene id: 34062:AXE82_RS03650
uniprot id: A0A378Q9T8
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

34062:AXE82 RS09870
gene id: 34062:AXE82_RS09870
uniprot id: A0A378QAX7
names: Similarity
messages: Belongs to the phosphohexose mutase family.

34062:AXE82 RS09105
gene id: 34062:AXE82_RS09105
uniprot id: A0A378QAY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Membrane

34062:AXE82 RS01060
gene id: 34062:AXE82_RS01060
uniprot id: A0A378QE35
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

34062:AXE82 RS09945
gene id: 34062:AXE82_RS09945
uniprot id: A0A378QBS9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LolA family.
messages: Monomer.
messages: Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).
messages: Periplasm

34062:AXE82 RS03025
gene id: 34062:AXE82_RS03025
uniprot id: A0A109WBD3
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

34062:AXE82 RS03045
gene id: 34062:AXE82_RS03045
uniprot id: A0A0X8K5B8
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

34062:AXE82 RS05490
gene id: 34062:AXE82_RS05490
uniprot id: A0A378Q8U6
names: Subcellular Location Annotation
messages: Membrane

34062:AXE82 RS01160
gene id: 34062:AXE82_RS01160
uniprot id: A0A378QAF7
names: Similarity
messages: Belongs to the transglycosylase Slt family.

34062:AXE82 RS02285
gene id: 34062:AXE82_RS02285
uniprot id: A0A378Q8R2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

34062:AXE82 RS02870
gene id: 34062:AXE82_RS02870
uniprot id: A0A378QA90
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

34062:AXE82 RS05170
gene id: 34062:AXE82_RS05170
uniprot id: A0A109WBL9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmE/CycJ family.
messages: Cell membrane
messages: Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.

34062:AXE82 RS11895
gene id: 34062:AXE82_RS11895
uniprot id: A0A173MSY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0391 family.
messages: Cell membrane

34062:AXE82 RS01040
gene id: 34062:AXE82_RS01040
uniprot id: A0A378Q9K5
names: Similarity
messages: Belongs to the malic enzymes family.
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the malic enzymes family.

34062:AXE82 RS08105
gene id: 34062:AXE82_RS08105
uniprot id: A0A0X8K709
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

34062:AXE82 RS09150
gene id: 34062:AXE82_RS09150
uniprot id: A0A378QBJ2
names: Similarity
messages: Belongs to the peptidase M24B family.

34062:AXE82 RS03175
gene id: 34062:AXE82_RS03175
uniprot id: A0A378Q973
names: Subcellular Location Annotation
messages: Membrane

34062:AXE82 RS06575
gene id: 34062:AXE82_RS06575
uniprot id: A0A109WBR7
names: Similarity
messages: Belongs to the MoaD family.

34062:AXE82 RS02475
gene id: 34062:AXE82_RS02475
uniprot id: A0A109WBA7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

34062:AXE82 RS04295
gene id: 34062:AXE82_RS04295
uniprot id: A0A0X8K5Y8
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

34062:AXE82 RS04595
gene id: 34062:AXE82_RS04595
uniprot id: A0A0X8K6D2
names: Function
names: Similarity
messages: Absolutely required for transposition of IS1.
messages: Belongs to the transposase 27 family.

34062:AXE82 RS09965
gene id: 34062:AXE82_RS09965
uniprot id: A0A0X8K7P9
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

34062:AXE82 RS02880
gene id: 34062:AXE82_RS02880
uniprot id: A0A378Q9D2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

34062:AXE82 RS10210
gene id: 34062:AXE82_RS10210
uniprot id: A0A109WC66
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

34062:AXE82 RS02625
gene id: 34062:AXE82_RS02625
uniprot id: A0A378Q9I1
names: Cofactor
names: Similarity
messages: Belongs to the monomeric-type IDH family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

34062:AXE82 RS07405
gene id: 34062:AXE82_RS07405
uniprot id: A0A378QD09
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

34062:AXE82 RS06365
gene id: 34062:AXE82_RS06365
uniprot id: A0A378Q7C9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

34062:AXE82 RS07110
gene id: 34062:AXE82_RS07110
uniprot id: A0A378Q6I6
names: Similarity
messages: Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily.

34062:AXE82 RS06235
gene id: 34062:AXE82_RS06235
uniprot id: A0A109WBQ5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

34062:AXE82 RS09935
gene id: 34062:AXE82_RS09935
uniprot id: A0A109WC65
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

34062:AXE82 RS04515
gene id: 34062:AXE82_RS04515
uniprot id: A0A378Q8G8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

34062:AXE82 RS01930
gene id: 34062:AXE82_RS01930
uniprot id: A0A378Q9F3
names: Subcellular Location Annotation
messages: Membrane

34062:AXE82 RS10665
gene id: 34062:AXE82_RS10665
uniprot id: A0A109WC82
names: Similarity
messages: Belongs to the PhoH family.

34062:AXE82 RS04415
gene id: 34062:AXE82_RS04415
uniprot id: A0A378Q834
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase E/G family. RNase E subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per homotetramer.
messages: Cell inner membrane
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation. Within the RNA degradosome, RNase E assembles into a homotetramer formed by a dimer of dimers.
messages: Cytoplasm
messages: Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs.

34062:AXE82 RS02005
gene id: 34062:AXE82_RS02005
uniprot id: A0A378QAR4
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

34062:AXE82 RS06500
gene id: 34062:AXE82_RS06500
uniprot id: A0A0X8K6F8
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

34062:AXE82 RS11695
gene id: 34062:AXE82_RS11695
uniprot id: A0A0X8K8Q1
names: Similarity
messages: Belongs to the transposase 7 family.

34062:AXE82 RS05735
gene id: 34062:AXE82_RS05735
uniprot id: A0A378Q6Y4
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

34062:AXE82 RS07685
gene id: 34062:AXE82_RS07685
uniprot id: A0A378QBT4
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

34062:AXE82 RS03390
gene id: 34062:AXE82_RS03390
uniprot id: A0A378Q8N2
names: Cofactor
names: Similarity
messages: Belongs to the UPF0313 family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

34062:AXE82 RS10710
gene id: 34062:AXE82_RS10710
uniprot id: A0A0X8K7Y7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

34062:AXE82 RS02745
gene id: 34062:AXE82_RS02745
uniprot id: A0A378Q8K3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-to-5' exoribonuclease specific for small oligoribonucleotides.
messages: Belongs to the oligoribonuclease family.
messages: Cytoplasm

34062:AXE82 RS05795
gene id: 34062:AXE82_RS05795
uniprot id: A0A378Q742
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Cytoplasm
messages: Homodimer.

34062:AXE82 RS11400
gene id: 34062:AXE82_RS11400
uniprot id: A0A378QVF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

34062:AXE82 RS06980
gene id: 34062:AXE82_RS06980
uniprot id: A0A0X8K898
names: Caution
names: Subcellular Location Annotation
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

34062:AXE82 RS07850
gene id: 34062:AXE82_RS07850
uniprot id: A0A378QBN7
names: Function
names: Subunit
messages: Adenylyltransferase that mediates the addition of adenosine 5'-monophosphate (AMP) to specific residues of target proteins.
messages: Homodimer.

34062:AXE82 RS11415
gene id: 34062:AXE82_RS11415
uniprot id: A0A109WCG8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

34062:AXE82 RS04965
gene id: 34062:AXE82_RS04965
uniprot id: A0A0X8K837
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

34062:AXE82 RS08455
gene id: 34062:AXE82_RS08455
uniprot id: A0A378QBN8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

34062:AXE82 RS03800
gene id: 34062:AXE82_RS03800
uniprot id: A0A378Q9R6
names: Similarity
messages: Belongs to the EfeM/EfeO family.

34062:AXE82 RS06590
gene id: 34062:AXE82_RS06590
uniprot id: A0A378Q6T2
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

34062:AXE82 RS02105
gene id: 34062:AXE82_RS02105
uniprot id: A0A0X8K7X7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

34062:AXE82 RS04735
gene id: 34062:AXE82_RS04735
uniprot id: A0A378Q7G0
names: Similarity
messages: Belongs to the SsuE family.

34062:AXE82 RS02275
gene id: 34062:AXE82_RS02275
uniprot id: A0A378Q9A6
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

34062:AXE82 RS06565
gene id: 34062:AXE82_RS06565
uniprot id: A0A0X8K6M5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

34062:AXE82 RS04305
gene id: 34062:AXE82_RS04305
uniprot id: A0A0X8K692
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

34062:AXE82 RS08255
gene id: 34062:AXE82_RS08255
uniprot id: A0A109WBY5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
messages: Forms an icosahedral capsid composed of 60 subunits, arranged as a dodecamer of pentamers.

34062:AXE82 RS05965
gene id: 34062:AXE82_RS05965
uniprot id: A0A378Q7W4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MinC family.
messages: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.
messages: Interacts with MinD and FtsZ.

34062:AXE82 RS08290
gene id: 34062:AXE82_RS08290
uniprot id: A0A378QBE6
names: Function
names: Similarity
messages: Belongs to the esterase D family.
messages: Serine hydrolase involved in the detoxification of formaldehyde.

34062:AXE82 RS10570
gene id: 34062:AXE82_RS10570
uniprot id: A0A378QAS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

34062:AXE82 RS08195
gene id: 34062:AXE82_RS08195
uniprot id: A0A0X8K713
names: Similarity
messages: Belongs to the pseudomonas-type ThrB family.

34062:AXE82 RS01020
gene id: 34062:AXE82_RS01020
uniprot id: A0A378QA11
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

34062:AXE82 RS04085
gene id: 34062:AXE82_RS04085
uniprot id: A0A378Q7V3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

34062:AXE82 RS01725
gene id: 34062:AXE82_RS01725
uniprot id: A0A0X8K4Y8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

34062:AXE82 RS11890
gene id: 34062:AXE82_RS11890
uniprot id: A0A378Q7H6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatB family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

34062:AXE82 RS01270
gene id: 34062:AXE82_RS01270
uniprot id: A0A378Q9V5
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.
messages: Cytoplasm

34062:AXE82 RS08930
gene id: 34062:AXE82_RS08930
uniprot id: A0A0X8K893
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

34062:AXE82 RS08315
gene id: 34062:AXE82_RS08315
uniprot id: A0A378QG09
names: Similarity
messages: Belongs to the YjdM family.

34062:AXE82 RS10125
gene id: 34062:AXE82_RS10125
uniprot id: A0A378QCA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

34062:AXE82 RS09620
gene id: 34062:AXE82_RS09620
uniprot id: A0A0X8K7Y5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

34062:AXE82 RS04480
gene id: 34062:AXE82_RS04480
uniprot id: A0A378Q820
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.

34062:AXE82 RS05215
gene id: 34062:AXE82_RS05215
uniprot id: A0A378QBR6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

34062:AXE82 RS10320
gene id: 34062:AXE82_RS10320
uniprot id: A0A378QAP0
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.

34062:AXE82 RS02300
gene id: 34062:AXE82_RS02300
uniprot id: A0A378Q8V0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP K family.
messages: Cell inner membrane
messages: Membrane

34062:AXE82 RS03255
gene id: 34062:AXE82_RS03255
uniprot id: A0A378Q899
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

34062:AXE82 RS03685
gene id: 34062:AXE82_RS03685
uniprot id: A0A378Q833
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

34062:AXE82 RS01705
gene id: 34062:AXE82_RS01705
uniprot id: A0A378QAX8
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

34062:AXE82 RS03610
gene id: 34062:AXE82_RS03610
uniprot id: A0A378Q8Z6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell inner membrane
messages: Component of the type II secretion system inner membrane complex required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.
messages: Membrane

34062:AXE82 RS07710
gene id: 34062:AXE82_RS07710
uniprot id: A0A120KR21
names: Similarity
messages: Belongs to the BolA/IbaG family.

34062:AXE82 RS08490
gene id: 34062:AXE82_RS08490
uniprot id: A0A120KR35
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

34062:AXE82 RS03780
gene id: 34062:AXE82_RS03780
uniprot id: A0A378Q8F0
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

34062:AXE82 RS01915
gene id: 34062:AXE82_RS01915
uniprot id: A0A378Q9H8
names: Function
names: Similarity
messages: Absolutely required for transposition of IS1.
messages: Belongs to the transposase 27 family.

34062:AXE82 RS04365
gene id: 34062:AXE82_RS04365
uniprot id: A0A0X8K5S7
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

34062:AXE82 RS02815
gene id: 34062:AXE82_RS02815
uniprot id: A0A378Q8R1
names: Similarity
messages: Belongs to the GSP E family.

34062:AXE82 RS03030
gene id: 34062:AXE82_RS03030
uniprot id: A0A0X8K5D9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RuvC family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.

34062:AXE82 RS09410
gene id: 34062:AXE82_RS09410
uniprot id: A0A378QC21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

34062:AXE82 RS04285
gene id: 34062:AXE82_RS04285
uniprot id: A0A0X8K5W0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

34062:AXE82 RS08365
gene id: 34062:AXE82_RS08365
uniprot id: A0A378QG01
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

34062:AXE82 RS03005
gene id: 34062:AXE82_RS03005
uniprot id: A0A378Q8M6
names: Cofactor
names: Similarity
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.

34062:AXE82 RS09830
gene id: 34062:AXE82_RS09830
uniprot id: A0A378QBN1
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. CmoM family.
messages: Catalyzes the methylation of 5-carboxymethoxyuridine (cmo5U) to form 5-methoxycarbonylmethoxyuridine (mcmo5U) at position 34 in tRNAs.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

34062:AXE82 RS04660
gene id: 34062:AXE82_RS04660
uniprot id: A0A109WBJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0394 family.
messages: Membrane

34062:AXE82 RS09690
gene id: 34062:AXE82_RS09690
uniprot id: A0A0X8K7Q5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

34062:AXE82 RS10715
gene id: 34062:AXE82_RS10715
uniprot id: A0A378QB67
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

34062:AXE82 RS05055
gene id: 34062:AXE82_RS05055
uniprot id: A0A109WGQ8
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of Lys-34 is required for alleviation.
messages: May be beta-lysylated on the epsilon-amino group of Lys-34 by the combined action of EpmA and EpmB, and then hydroxylated on the C5 position of the same residue by EpmC (if this protein is present). Lysylation is critical for the stimulatory effect of EF-P on peptide-bond formation. The lysylation moiety may extend toward the peptidyltransferase center and stabilize the terminal 3-CCA end of the tRNA. Hydroxylation of the C5 position on Lys-34 may allow additional potential stabilizing hydrogen-bond interactions with the P-tRNA.

34062:AXE82 RS08140
gene id: 34062:AXE82_RS08140
uniprot id: A0A0X8K6Z6
names: Function
names: Similarity
messages: Belongs to the uroporphyrinogen-III synthase family.
messages: Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.

34062:AXE82 RS11185
gene id: 34062:AXE82_RS11185
uniprot id: A0A0X8K8J4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

34062:AXE82 RS08990
gene id: 34062:AXE82_RS08990
uniprot id: A0A378QBI1
names: Cofactor
messages: Can also use Mn(2+) ion.

34062:AXE82 RS07115
gene id: 34062:AXE82_RS07115
uniprot id: A0A378Q798
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsbB family.
messages: Cell inner membrane
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein.

34062:AXE82 RS04610
gene id: 34062:AXE82_RS04610
uniprot id: A0A378Q9B6
names: Similarity
messages: Belongs to the metallo-beta-lactamase superfamily. Type III sulfatase family.

34062:AXE82 RS00410
gene id: 34062:AXE82_RS00410
uniprot id: A0A378QBN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

34062:AXE82 RS06560
gene id: 34062:AXE82_RS06560
uniprot id: A0A0X8K6Y8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

34062:AXE82 RS06355
gene id: 34062:AXE82_RS06355
uniprot id: A0A0X8K6L0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

34062:AXE82 RS08405
gene id: 34062:AXE82_RS08405
uniprot id: A0A378QBP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell inner membrane
messages: Membrane

34062:AXE82 RS10575
gene id: 34062:AXE82_RS10575
uniprot id: A0A378QBF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

34062:AXE82 RS05925
gene id: 34062:AXE82_RS05925
uniprot id: A0A378Q754
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

34062:AXE82 RS09090
gene id: 34062:AXE82_RS09090
uniprot id: A0A378QC19
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the R-transferase family. Bpt subfamily.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate.

34062:AXE82 RS11030
gene id: 34062:AXE82_RS11030
uniprot id: A0A0X8K8D7
names: Similarity
messages: Belongs to the peptidase S24 family.

34062:AXE82 RS09190
gene id: 34062:AXE82_RS09190
uniprot id: A0A378QCS8
names: Function
names: Similarity
messages: Belongs to the MoaB/Mog family.
messages: May be involved in the biosynthesis of molybdopterin.

34062:AXE82 RS02460
gene id: 34062:AXE82_RS02460
uniprot id: A0A378Q8Y1
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.

34062:AXE82 RS03900
gene id: 34062:AXE82_RS03900
uniprot id: A0A378QCI1
names: Similarity
messages: Belongs to the GSP E family.

34062:AXE82 RS00950
gene id: 34062:AXE82_RS00950
uniprot id: A0A378Q9U4
names: Domain
names: Function
names: Subcellular Location Annotation
messages: Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation.
messages: Periplasm
messages: The PPIase activity resides only in the second parvulin domain. The N-terminal region and the C-terminal tail are necessary and sufficient for the chaperone activity of SurA. The PPIase activity is dispensable for SurA to function as a chaperone. The N-terminal region and the C-terminal tail are also required for porin recognition.

34062:AXE82 RS03300
gene id: 34062:AXE82_RS03300
uniprot id: A0A378Q865
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the glyoxalase I family.
messages: Binds 1 nickel ion per subunit.
messages: Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.

34062:AXE82 RS04355
gene id: 34062:AXE82_RS04355
uniprot id: A0A0X8K602
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

34062:AXE82 RS00190
gene id: 34062:AXE82_RS00190
uniprot id: A0A378QA20
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dsrC/tusE family.
messages: Cytoplasm
messages: Part of a sulfur-relay system.

34062:AXE82 RS02165
gene id: 34062:AXE82_RS02165
uniprot id: A0A378Q9C7
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

34062:AXE82 RS08250
gene id: 34062:AXE82_RS08250
uniprot id: A0A378QBH5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

34062:AXE82 RS06790
gene id: 34062:AXE82_RS06790
uniprot id: A0A378Q6P1
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

34062:AXE82 RS10155
gene id: 34062:AXE82_RS10155
uniprot id: A0A378QAW1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

34062:AXE82 RS11280
gene id: 34062:AXE82_RS11280
uniprot id: A0A378QVH7
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

34062:AXE82 RS07975
gene id: 34062:AXE82_RS07975
uniprot id: A0A0X8K6X9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease gamma subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

34062:AXE82 RS01675
gene id: 34062:AXE82_RS01675
uniprot id: A0A0X8K5F6
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

34062:AXE82 RS01115
gene id: 34062:AXE82_RS01115
uniprot id: A0A0X8K4Y0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

34062:AXE82 RS06270
gene id: 34062:AXE82_RS06270
uniprot id: A0A0X8K6E5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

34062:AXE82 RS05445
gene id: 34062:AXE82_RS05445
uniprot id: A0A378QBM4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

34062:AXE82 RS03960
gene id: 34062:AXE82_RS03960
uniprot id: A0A378Q8C8
names: Similarity
messages: Belongs to the transglycosylase Slt family.

34062:AXE82 RS08975
gene id: 34062:AXE82_RS08975
uniprot id: A0A378QBN2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

34062:AXE82 RS08955
gene id: 34062:AXE82_RS08955
uniprot id: A0A378QBD3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

34062:AXE82 RS03590
gene id: 34062:AXE82_RS03590
uniprot id: A0A0X8K5K3
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

34062:AXE82 RS03450
gene id: 34062:AXE82_RS03450
uniprot id: A0A378Q9X8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YciB family.
messages: Cell inner membrane
messages: Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.

34062:AXE82 RS04720
gene id: 34062:AXE82_RS04720
uniprot id: A0A378Q8D0
names: Function
names: Similarity
messages: Belongs to the SsuD family.
messages: Catalyzes the desulfonation of aliphatic sulfonates.

34062:AXE82 RS02720
gene id: 34062:AXE82_RS02720
uniprot id: A0A378QD51
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the calycin superfamily. Lipocalin family.
messages: Cell outer membrane
messages: Homodimer.
messages: Involved in the storage or transport of lipids necessary for membrane maintenance under stressful conditions. Displays a binding preference for lysophospholipids.

34062:AXE82 RS03785
gene id: 34062:AXE82_RS03785
uniprot id: A0A0X8K5K0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein L14 (rplN).

34062:AXE82 RS09420
gene id: 34062:AXE82_RS09420
uniprot id: A0A378QBA2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.
messages: Serves to protect the cell against DNA damage by alkyl hydroperoxides. It can use either NADH or NADPH as electron donor for direct reduction of redox dyes or of alkyl hydroperoxides when combined with the AhpC protein.

34062:AXE82 RS00645
gene id: 34062:AXE82_RS00645
uniprot id: A0A378Q9U5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

34062:AXE82 RS06830
gene id: 34062:AXE82_RS06830
uniprot id: A0A0X8K6M7
names: Subcellular Location Annotation
messages: Membrane

34062:AXE82 RS10720
gene id: 34062:AXE82_RS10720
uniprot id: A0A378QAP6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

34062:AXE82 RS07905
gene id: 34062:AXE82_RS07905
uniprot id: A0A378QBZ3
names: Similarity
messages: Belongs to the HipA Ser/Thr kinase family.

34062:AXE82 RS06815
gene id: 34062:AXE82_RS06815
uniprot id: A0A378Q6A4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family. ParE type 1 subfamily.
messages: Cytoplasm
messages: Heterotetramer composed of ParC and ParE.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

34062:AXE82 RS03690
gene id: 34062:AXE82_RS03690
uniprot id: A0A0X8K7I4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

34062:AXE82 RS08100
gene id: 34062:AXE82_RS08100
uniprot id: A0A378QDE1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

34062:AXE82 RS01740
gene id: 34062:AXE82_RS01740
uniprot id: A0A378Q962
names: Similarity
messages: Belongs to the MipA/OmpV family.

34062:AXE82 RS02785
gene id: 34062:AXE82_RS02785
uniprot id: A0A378Q8G2
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

34062:AXE82 RS08400
gene id: 34062:AXE82_RS08400
uniprot id: A0A0X8K724
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The autoendoproteolytic cleavage occurs by a canonical serine protease mechanism, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. During this reaction, the Ser that is part of the protease active site of the proenzyme becomes the pyruvoyl prosthetic group, which constitutes an essential element of the active site of the mature decarboxylase.

34062:AXE82 RS08270
gene id: 34062:AXE82_RS08270
uniprot id: A0A0X8K760
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG).

34062:AXE82 RS02575
gene id: 34062:AXE82_RS02575
uniprot id: A0A378QAF0
names: Similarity
messages: Belongs to the aspartokinase family.

34062:AXE82 RS06435
gene id: 34062:AXE82_RS06435
uniprot id: A0A378QB33
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

34062:AXE82 RS03305
gene id: 34062:AXE82_RS03305
uniprot id: A0A0X8K5J8
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.

34062:AXE82 RS08840
gene id: 34062:AXE82_RS08840
uniprot id: A0A378QB62
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

34062:AXE82 RS04440
gene id: 34062:AXE82_RS04440
uniprot id: A0A378Q7P0
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

34062:AXE82 RS03810
gene id: 34062:AXE82_RS03810
uniprot id: A0A0X8K5P1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

34062:AXE82 RS05725
gene id: 34062:AXE82_RS05725
uniprot id: A0A378Q6U1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

34062:AXE82 RS11025
gene id: 34062:AXE82_RS11025
uniprot id: A0A378QVD8
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.

34062:AXE82 RS09955
gene id: 34062:AXE82_RS09955
uniprot id: A0A0X8K7L5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

34062:AXE82 RS02120
gene id: 34062:AXE82_RS02120
uniprot id: A0A378Q9D9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

34062:AXE82 RS05690
gene id: 34062:AXE82_RS05690
uniprot id: A0A378Q8Q5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

34062:AXE82 RS08410
gene id: 34062:AXE82_RS08410
uniprot id: A0A378QD74
names: Similarity
messages: Belongs to the DODA-type extradiol aromatic ring-opening dioxygenase family.

34062:AXE82 RS04560
gene id: 34062:AXE82_RS04560
uniprot id: A0A378Q9C6
names: Similarity
messages: Belongs to the YkuD family.

34062:AXE82 RS02965
gene id: 34062:AXE82_RS02965
uniprot id: A0A0X8K5B4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

34062:AXE82 RS08885
gene id: 34062:AXE82_RS08885
uniprot id: A0A378QBK7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsB family.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

34062:AXE82 RS03250
gene id: 34062:AXE82_RS03250
uniprot id: A0A378Q8A8
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

34062:AXE82 RS06250
gene id: 34062:AXE82_RS06250
uniprot id: A0A0X8K6M0
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

34062:AXE82 RS03310
gene id: 34062:AXE82_RS03310
uniprot id: A0A378Q898
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

34062:AXE82 RS00730
gene id: 34062:AXE82_RS00730
uniprot id: A0A378QAV4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.

34062:AXE82 RS10675
gene id: 34062:AXE82_RS10675
uniprot id: A0A378QBD6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Catalyzes the sodium-dependent uptake of extracellular L-proline.
messages: Cell inner membrane
messages: Membrane

34062:AXE82 RS01045
gene id: 34062:AXE82_RS01045
uniprot id: A0A378Q9G7
names: Function
names: Similarity
messages: Belongs to the SELO family.
messages: Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).

34062:AXE82 RS04410
gene id: 34062:AXE82_RS04410
uniprot id: A0A109WBI6
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

34062:AXE82 RS05930
gene id: 34062:AXE82_RS05930
uniprot id: A0A378Q6U5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiC family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway.

34062:AXE82 RS03125
gene id: 34062:AXE82_RS03125
uniprot id: A0A0X8K802
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

34062:AXE82 RS04190
gene id: 34062:AXE82_RS04190
uniprot id: A0A378Q7T5
names: Similarity
messages: Belongs to the UPF0053 family.

34062:AXE82 RS03520
gene id: 34062:AXE82_RS03520
uniprot id: A0A378Q9C0
names: Similarity
messages: Belongs to the polysaccharide synthase family.

34062:AXE82 RS08585
gene id: 34062:AXE82_RS08585
uniprot id: A0A378QB81
names: Similarity
messages: Belongs to the SdhE FAD assembly factor family.

34062:AXE82 RS05710
gene id: 34062:AXE82_RS05710
uniprot id: A0A378Q7Q7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

34062:AXE82 RS06925
gene id: 34062:AXE82_RS06925
uniprot id: A0A378QAS9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

34062:AXE82 RS09230
gene id: 34062:AXE82_RS09230
uniprot id: A0A378QB90
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.

34062:AXE82 RS00095
gene id: 34062:AXE82_RS00095
uniprot id: A0A378QAC5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homotetramer.

34062:AXE82 RS07265
gene id: 34062:AXE82_RS07265
uniprot id: A0A0X8K6V0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

34062:AXE82 RS07450
gene id: 34062:AXE82_RS07450
uniprot id: A0A378QGG9
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

34062:AXE82 RS00560
gene id: 34062:AXE82_RS00560
uniprot id: A0A378QAS3
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

34062:AXE82 RS06850
gene id: 34062:AXE82_RS06850
uniprot id: A0A378Q6M0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

34062:AXE82 RS04290
gene id: 34062:AXE82_RS04290
uniprot id: A0A0X8K5R9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

34062:AXE82 RS05680
gene id: 34062:AXE82_RS05680
uniprot id: A0A378Q6Y6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell inner membrane
messages: Membrane

34062:AXE82 RS10830
gene id: 34062:AXE82_RS10830
uniprot id: A0A378QVC0
names: Similarity
messages: Belongs to the RelB/DinJ antitoxin family.

34062:AXE82 RS00135
gene id: 34062:AXE82_RS00135
uniprot id: A0A378QA31
names: Similarity
messages: Belongs to the peptidase M16 family.

34062:AXE82 RS04265
gene id: 34062:AXE82_RS04265
uniprot id: A0A378Q8X1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

34062:AXE82 RS04225
gene id: 34062:AXE82_RS04225
uniprot id: A0A0X8K5T9
names: Similarity
messages: Belongs to the BolA/IbaG family.

34062:AXE82 RS08855
gene id: 34062:AXE82_RS08855
uniprot id: A0A378QCY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

34062:AXE82 RS04390
gene id: 34062:AXE82_RS04390
uniprot id: A0A0X8K5W1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

34062:AXE82 RS01685
gene id: 34062:AXE82_RS01685
uniprot id: A0A378Q9J9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic sulfate-binding protein family.
messages: Periplasm

34062:AXE82 RS03150
gene id: 34062:AXE82_RS03150
uniprot id: A0A378Q8C7
names: Subcellular Location Annotation
messages: Membrane

34062:AXE82 RS05630
gene id: 34062:AXE82_RS05630
uniprot id: A0A109WBN1
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

34062:AXE82 RS09985
gene id: 34062:AXE82_RS09985
uniprot id: A0A0X8K7K6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

34062:AXE82 RS09330
gene id: 34062:AXE82_RS09330
uniprot id: A0A378QAU9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

34062:AXE82 RS00535
gene id: 34062:AXE82_RS00535
uniprot id: A0A0X8K4J8
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

34062:AXE82 RS04220
gene id: 34062:AXE82_RS04220
uniprot id: A0A378Q8Y3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

34062:AXE82 RS06770
gene id: 34062:AXE82_RS06770
uniprot id: A0A109WBT2
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

34062:AXE82 RS06970
gene id: 34062:AXE82_RS06970
uniprot id: A0A0X8K6V3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DksA family.
messages: Cytoplasm
messages: Interacts directly with the RNA polymerase.
messages: Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression.

34062:AXE82 RS09865
gene id: 34062:AXE82_RS09865
uniprot id: A0A378QAJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

34062:AXE82 RS05610
gene id: 34062:AXE82_RS05610
uniprot id: A0A0X8K658
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

34062:AXE82 RS09570
gene id: 34062:AXE82_RS09570
uniprot id: A0A109WH50
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

34062:AXE82 RS09370
gene id: 34062:AXE82_RS09370
uniprot id: A0A378QBB4
names: Subcellular Location Annotation
messages: Cytoplasm

34062:AXE82 RS06920
gene id: 34062:AXE82_RS06920
uniprot id: A0A378Q7Z1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

34062:AXE82 RS07970
gene id: 34062:AXE82_RS07970
uniprot id: A0A378QC76
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UreD family.
messages: Cytoplasm
messages: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
messages: UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

34062:AXE82 RS08065
gene id: 34062:AXE82_RS08065
uniprot id: A0A378QCM6
names: Subcellular Location Annotation
messages: Membrane

34062:AXE82 RS06800
gene id: 34062:AXE82_RS06800
uniprot id: A0A378Q679
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.

34062:AXE82 RS05975
gene id: 34062:AXE82_RS05975
uniprot id: A0A109WBQ6
names: Function
names: Similarity
messages: Belongs to the MinE family.
messages: Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.

34062:AXE82 RS05655
gene id: 34062:AXE82_RS05655
uniprot id: A0A0X8K6E3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NfuA family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is presumably bound at the interface of two monomers.
messages: Homodimer.
messages: Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins.

34062:AXE82 RS09975
gene id: 34062:AXE82_RS09975
uniprot id: A0A378QCD2
names: Similarity
names: Subunit
messages: Belongs to the complex I 75 kDa subunit family.
messages: Composed of 13 different subunits. Subunits NuoCD, E, F, and G constitute the peripheral sector of the complex.

34062:AXE82 RS01200
gene id: 34062:AXE82_RS01200
uniprot id: A0A378QB84
names: Similarity
messages: Belongs to the heat shock protein 70 family.

34062:AXE82 RS05555
gene id: 34062:AXE82_RS05555
uniprot id: A0A378Q7D5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

34062:AXE82 RS09030
gene id: 34062:AXE82_RS09030
uniprot id: A0A120KR66
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

34062:AXE82 RS00850
gene id: 34062:AXE82_RS00850
uniprot id: A0A378Q9K1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

34062:AXE82 RS00500
gene id: 34062:AXE82_RS00500
uniprot id: A0A378QA38
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

34062:AXE82 RS08090
gene id: 34062:AXE82_RS08090
uniprot id: A0A0X8K717
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

34062:AXE82 RS06715
gene id: 34062:AXE82_RS06715
uniprot id: A0A378Q6C8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cx-SAM synthase family.
messages: Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

34062:AXE82 RS02425
gene id: 34062:AXE82_RS02425
uniprot id: A0A378Q9M6
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.

34062:AXE82 RS08175
gene id: 34062:AXE82_RS08175
uniprot id: A0A0X8K747
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

34062:AXE82 RS07675
gene id: 34062:AXE82_RS07675
uniprot id: A0A378QBS1
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

34062:AXE82 RS04230
gene id: 34062:AXE82_RS04230
uniprot id: A0A378Q866
names: Similarity
messages: Belongs to the UPF0102 family.

34062:AXE82 RS00435
gene id: 34062:AXE82_RS00435
uniprot id: A0A378Q9T1
names: Function
names: Similarity
messages: Belongs to the GSP L family.
messages: Inner membrane component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.

34062:AXE82 RS11100
gene id: 34062:AXE82_RS11100
uniprot id: A0A378QWY1
names: Similarity
messages: Belongs to the allantoicase family.

34062:AXE82 RS09130
gene id: 34062:AXE82_RS09130
uniprot id: A0A0X8K7E3
names: Function
names: Similarity
names: Subunit
messages: Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division.
messages: Belongs to the ZapA family. Type 1 subfamily.
messages: Homodimer. Interacts with FtsZ.

34062:AXE82 RS02715
gene id: 34062:AXE82_RS02715
uniprot id: A0A378QAB9
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

34062:AXE82 RS08495
gene id: 34062:AXE82_RS08495
uniprot id: A0A0X8K739
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

34062:AXE82 RS03335
gene id: 34062:AXE82_RS03335
uniprot id: A0A378Q941
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein PotD/PotF family.
messages: Periplasm
messages: Required for the activity of the bacterial periplasmic transport system of putrescine.

34062:AXE82 RS06215
gene id: 34062:AXE82_RS06215
uniprot id: A0A378Q7R1
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

34062:AXE82 RS09680
gene id: 34062:AXE82_RS09680
uniprot id: A0A109WC45
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 3 family. NagZ subfamily.
messages: Cytoplasm
messages: Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides.

34062:AXE82 RS00445
gene id: 34062:AXE82_RS00445
uniprot id: A0A378Q9W8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

34062:AXE82 RS03495
gene id: 34062:AXE82_RS03495
uniprot id: A0A378Q8E2
names: Subcellular Location Annotation
messages: Membrane

34062:AXE82 RS07100
gene id: 34062:AXE82_RS07100
uniprot id: A0A120KRA3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HesB/IscA family.
messages: Binds 1 iron-sulfur cluster per subunit.
messages: Homodimer.
messages: Required for insertion of 4Fe-4S clusters for at least IspG.

34062:AXE82 RS08345
gene id: 34062:AXE82_RS08345
uniprot id: A0A378QBF8
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

34062:AXE82 RS04775
gene id: 34062:AXE82_RS04775
uniprot id: A0A378Q7V7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

34062:AXE82 RS11490
gene id: 34062:AXE82_RS11490
uniprot id: A0A378QWZ5
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

34062:AXE82 RS00675
gene id: 34062:AXE82_RS00675
uniprot id: A0A378QA79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

34062:AXE82 RS04205
gene id: 34062:AXE82_RS04205
uniprot id: A0A378QCC1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

34062:AXE82 RS01780
gene id: 34062:AXE82_RS01780
uniprot id: A0A378Q907
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

34062:AXE82 RS09615
gene id: 34062:AXE82_RS09615
uniprot id: A0A378QBA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial secretin family.
messages: Cell outer membrane
messages: Membrane

34062:AXE82 RS00085
gene id: 34062:AXE82_RS00085
uniprot id: A0A378QA37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell inner membrane
messages: Membrane

34062:AXE82 RS01325
gene id: 34062:AXE82_RS01325
uniprot id: A0A0X8K4V6
names: Function
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

34062:AXE82 RS07050
gene id: 34062:AXE82_RS07050
uniprot id: A0A109WBT8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

34062:AXE82 RS03895
gene id: 34062:AXE82_RS03895
uniprot id: A0A378Q9P8
names: Similarity
messages: Belongs to the GSP E family.

34062:AXE82 RS05945
gene id: 34062:AXE82_RS05945
uniprot id: A0A378Q8K1
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

34062:AXE82 RS07375
gene id: 34062:AXE82_RS07375
uniprot id: A0A120KR15
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
messages: Homodimer.

34062:AXE82 RS00700
gene id: 34062:AXE82_RS00700
uniprot id: A0A109WB35
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
messages: Cytoplasm
messages: Homotrimer.
messages: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

34062:AXE82 RS09100
gene id: 34062:AXE82_RS09100
uniprot id: A0A378QC79
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

34062:AXE82 RS09295
gene id: 34062:AXE82_RS09295
uniprot id: A0A378QFI7
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.

34062:AXE82 RS01250
gene id: 34062:AXE82_RS01250
uniprot id: A0A378QB74
names: Cofactor
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.

34062:AXE82 RS05550
gene id: 34062:AXE82_RS05550
uniprot id: A0A0X8K666
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

34062:AXE82 RS02185
gene id: 34062:AXE82_RS02185
uniprot id: A0A378Q8W8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
messages: Cell inner membrane
messages: Membrane

34062:AXE82 RS02710
gene id: 34062:AXE82_RS02710
uniprot id: A0A0X8K5E6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

34062:AXE82 RS08965
gene id: 34062:AXE82_RS08965
uniprot id: A0A120KR42
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

34062:AXE82 RS00265
gene id: 34062:AXE82_RS00265
uniprot id: A0A378QAY4
names: Similarity
messages: Belongs to the RlpA family.

34062:AXE82 RS07285
gene id: 34062:AXE82_RS07285
uniprot id: A0A109WBW1
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

34062:AXE82 RS01265
gene id: 34062:AXE82_RS01265
uniprot id: A0A378QAD4
names: Function
names: Similarity
messages: Belongs to the transaldolase family. Type 1 subfamily.
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

34062:AXE82 RS04310
gene id: 34062:AXE82_RS04310
uniprot id: A0A0X8K5X2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

34062:AXE82 RS05175
gene id: 34062:AXE82_RS05175
uniprot id: A0A0X8K628
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmD/CycX/HelD family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

34062:AXE82 RS05160
gene id: 34062:AXE82_RS05160
uniprot id: A0A109WBL1
names: Subcellular Location Annotation
messages: Membrane

34062:AXE82 RS00540
gene id: 34062:AXE82_RS00540
uniprot id: A0A378Q9V4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

34062:AXE82 RS02480
gene id: 34062:AXE82_RS02480
uniprot id: A0A0X8K7Z2
names: Similarity
messages: Belongs to the UPF0250 family.

34062:AXE82 RS02365
gene id: 34062:AXE82_RS02365
uniprot id: A0A378QAJ2
names: Similarity
messages: Belongs to the flavin oxidoreductase frp family.

34062:AXE82 RS09290
gene id: 34062:AXE82_RS09290
uniprot id: A0A378QCR2
names: Function
names: Similarity
messages: Belongs to the bacterioferritin family.
messages: Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.

34062:AXE82 RS07465
gene id: 34062:AXE82_RS07465
uniprot id: A0A378QD43
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

34062:AXE82 RS05875
gene id: 34062:AXE82_RS05875
uniprot id: A0A0X8K685
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

34062:AXE82 RS02345
gene id: 34062:AXE82_RS02345
uniprot id: A0A378Q978
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family.
messages: Cytoplasm
messages: Homotrimer.

34062:AXE82 RS01720
gene id: 34062:AXE82_RS01720
uniprot id: A0A378Q9L8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

34062:AXE82 RS04140
gene id: 34062:AXE82_RS04140
uniprot id: A0A378Q7U5
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

34062:AXE82 RS02975
gene id: 34062:AXE82_RS02975
uniprot id: A0A0X8K5E1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

34062:AXE82 RS00845
gene id: 34062:AXE82_RS00845
uniprot id: A0A378Q9Q1
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

34062:AXE82 RS09555
gene id: 34062:AXE82_RS09555
uniprot id: A0A0X8K7I6
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

34062:AXE82 RS03820
gene id: 34062:AXE82_RS03820
uniprot id: A0A378Q964
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PstS family.
messages: Part of the ABC transporter complex PstSACB involved in phosphate import.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

34062:AXE82 RS06540
gene id: 34062:AXE82_RS06540
uniprot id: A0A378Q6U3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

34062:AXE82 RS10365
gene id: 34062:AXE82_RS10365
uniprot id: A0A378QAA3
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

34062:AXE82 RS02615
gene id: 34062:AXE82_RS02615
uniprot id: A0A0X8K5D6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

34062:AXE82 RS02565
gene id: 34062:AXE82_RS02565
uniprot id: A0A378Q8N5
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

34062:AXE82 RS08135
gene id: 34062:AXE82_RS08135
uniprot id: A0A109WBX7
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

34062:AXE82 RS03675
gene id: 34062:AXE82_RS03675
uniprot id: A0A0X8K5L5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

34062:AXE82 RS02850
gene id: 34062:AXE82_RS02850
uniprot id: A0A378Q8X9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

34062:AXE82 RS08515
gene id: 34062:AXE82_RS08515
uniprot id: A0A378QFX0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

34062:AXE82 RS10195
gene id: 34062:AXE82_RS10195
uniprot id: A0A378QBM5
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The Rieske protein is a high potential 2Fe-2S protein.
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

34062:AXE82 RS01755
gene id: 34062:AXE82_RS01755
uniprot id: A0A378QAW6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

34062:AXE82 RS03190
gene id: 34062:AXE82_RS03190
uniprot id: A0A378Q885
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

34062:AXE82 RS11735
gene id: 34062:AXE82_RS11735
uniprot id: A0A378QX61
names: Subcellular Location Annotation
messages: Membrane

34062:AXE82 RS05535
gene id: 34062:AXE82_RS05535
uniprot id: A0A378Q790
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

34062:AXE82 RS03295
gene id: 34062:AXE82_RS03295
uniprot id: A0A378Q9F7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the aerobic coproporphyrinogen-III oxidase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

34062:AXE82 RS02770
gene id: 34062:AXE82_RS02770
uniprot id: A0A0X8K7Y8
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

34062:AXE82 RS06135
gene id: 34062:AXE82_RS06135
uniprot id: A0A120KQZ7
names: Function
names: Similarity
messages: Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
messages: Belongs to the Nudix hydrolase family. RppH subfamily.

34062:AXE82 RS01960
gene id: 34062:AXE82_RS01960
uniprot id: A0A378Q9Z0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the etk/wzc family.
messages: Cell inner membrane
messages: Membrane

34062:AXE82 RS02760
gene id: 34062:AXE82_RS02760
uniprot id: A0A0X8K5H1
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.

34062:AXE82 RS10160
gene id: 34062:AXE82_RS10160
uniprot id: A0A378QAI0
names: Similarity
messages: Belongs to the RutC family.

34062:AXE82 RS08870
gene id: 34062:AXE82_RS08870
uniprot id: A0A109WC21
names: Function
names: Subcellular Location Annotation
messages: Chaperone that serves for the intracellular sequestration and transport of Cu(+). Delivers Cu(+) to the copper-exporting P-type ATPase A (CopA).
messages: Cytoplasm

34062:AXE82 RS07250
gene id: 34062:AXE82_RS07250
uniprot id: A0A378QDW1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

34062:AXE82 RS11435
gene id: 34062:AXE82_RS11435
uniprot id: A0A0X8K8M0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

34062:AXE82 RS04100
gene id: 34062:AXE82_RS04100
uniprot id: A0A378QCD9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family.
messages: Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
messages: Cell inner membrane

34062:AXE82 RS00945
gene id: 34062:AXE82_RS00945
uniprot id: A0A378Q9I5
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

34062:AXE82 RS01610
gene id: 34062:AXE82_RS01610
uniprot id: A0A378QDS7
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA.
messages: Belongs to the helicase family. UvrD subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding. Interacts with RecA.
messages: The C-terminal domain has nuclease activity and interacts with RecD. It interacts with RecA, facilitating its loading onto ssDNA.
messages: The N-terminal DNA-binding domain is a ssDNA-dependent ATPase and has ATP-dependent 3'-5' helicase function. This domain interacts with RecC.

34062:AXE82 RS08780
gene id: 34062:AXE82_RS08780
uniprot id: A0A378QCD4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

34062:AXE82 RS03845
gene id: 34062:AXE82_RS03845
uniprot id: A0A378Q877
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane

34062:AXE82 RS03915
gene id: 34062:AXE82_RS03915
uniprot id: A0A378Q947
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

34062:AXE82 RS11560
gene id: 34062:AXE82_RS11560
uniprot id: A0A378QVL5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial microcompartment
messages: Belongs to the EutB family.
messages: Binds between the large and small subunits.
messages: Catalyzes the deamination of various vicinal amino-alcohols to oxo compounds. Allows this organism to utilize ethanolamine as the sole source of nitrogen and carbon in the presence of vitamin B12.
messages: The basic unit is a heterodimer which dimerizes to form tetramers. The heterotetramers trimerize; 6 large subunits form a core ring with 6 small subunits projecting outwards.

34062:AXE82 RS08110
gene id: 34062:AXE82_RS08110
uniprot id: A0A0X8K794
names: Function
names: Similarity
messages: Belongs to the Fe(2+)-trafficking protein family.
messages: Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.

34062:AXE82 RS01055
gene id: 34062:AXE82_RS01055
uniprot id: A0A378QBB0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

34062:AXE82 RS08015
gene id: 34062:AXE82_RS08015
uniprot id: A0A378QCN6
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

34062:AXE82 RS04025
gene id: 34062:AXE82_RS04025
uniprot id: A0A378Q8A0
names: Similarity
messages: Belongs to the long-chain O-acyltransferase family.

34062:AXE82 RS02925
gene id: 34062:AXE82_RS02925
uniprot id: A0A378Q9C3
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins.

34062:AXE82 RS07550
gene id: 34062:AXE82_RS07550
uniprot id: A0A109WBV9
names: Function
names: Similarity
messages: Belongs to the RapZ-like family.
messages: Displays ATPase and GTPase activities.

34062:AXE82 RS00670
gene id: 34062:AXE82_RS00670
uniprot id: A0A378QAQ2
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

34062:AXE82 RS02415
gene id: 34062:AXE82_RS02415
uniprot id: A0A378QAI4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.
messages: Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate.
messages: Homotetramer; dimer of dimers.
messages: Involved in the catabolism of short chain fatty acids (SCFA) via the 2-methylcitrate cycle (propionate degradation route). Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate via an alpha-carboxy-carbanion intermediate.

34062:AXE82 RS10650
gene id: 34062:AXE82_RS10650
uniprot id: A0A378QBZ9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

34062:AXE82 RS09050
gene id: 34062:AXE82_RS09050
uniprot id: A0A378QB02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial secretin family. GSP D subfamily.
messages: Cell outer membrane
messages: Membrane

34062:AXE82 RS00225
gene id: 34062:AXE82_RS00225
uniprot id: A0A378QB66
names: Similarity
messages: Belongs to the TrpC family.

34062:AXE82 RS00880
gene id: 34062:AXE82_RS00880
uniprot id: A0A0X8K4N7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCF family. Uup subfamily.
messages: Cytoplasm
messages: Probably plays a role in ribosome assembly or function. May be involved in resolution of branched DNA intermediates that result from template switching in postreplication gaps. Binds DNA and has ATPase activity.

34062:AXE82 RS05155
gene id: 34062:AXE82_RS05155
uniprot id: A0A109WBM7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

34062:AXE82 RS04520
gene id: 34062:AXE82_RS04520
uniprot id: A0A0X8K5U6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Membrane

34062:AXE82 RS07315
gene id: 34062:AXE82_RS07315
uniprot id: A0A378QD73
names: Function
names: Similarity
messages: Belongs to the MurCDEF family. Mpl subfamily.
messages: Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl-meso-diaminopimelate by linking it to UDP-N-acetylmuramate.

34062:AXE82 RS00230
gene id: 34062:AXE82_RS00230
uniprot id: A0A378Q9X3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

34062:AXE82 RS11590
gene id: 34062:AXE82_RS11590
uniprot id: A0A378QX16
names: Subcellular Location Annotation
messages: Membrane

34062:AXE82 RS10785
gene id: 34062:AXE82_RS10785
uniprot id: A0A378QAJ4
names: Similarity
messages: Belongs to the glycosyltransferase 20 family.

34062:AXE82 RS02920
gene id: 34062:AXE82_RS02920
uniprot id: A0A378QD12
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

34062:AXE82 RS04335
gene id: 34062:AXE82_RS04335
uniprot id: A0A109WBH7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

34062:AXE82 RS06785
gene id: 34062:AXE82_RS06785
uniprot id: A0A0X8K8D5
names: Caution
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetyltransferase family. ArgA subfamily.
messages: Cytoplasm
messages: In bacteria which possess the bifunctional enzyme ornithine acetyltransferase/N-acetylglutamate synthase (ArgJ), ArgA fulfills an anaplerotic role.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

34062:AXE82 RS00575
gene id: 34062:AXE82_RS00575
uniprot id: A0A378Q9Q0
names: Subcellular Location Annotation
messages: Membrane

34062:AXE82 RS00125
gene id: 34062:AXE82_RS00125
uniprot id: A0A378Q9Z4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. MrdB/RodA subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell wall elongation.

34062:AXE82 RS08265
gene id: 34062:AXE82_RS08265
uniprot id: A0A378QDA7
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

34062:AXE82 RS05245
gene id: 34062:AXE82_RS05245
uniprot id: A0A378Q774
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

34062:AXE82 RS05715
gene id: 34062:AXE82_RS05715
uniprot id: A0A378Q796
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

34062:AXE82 RS01475
gene id: 34062:AXE82_RS01475
uniprot id: A0A378QAF5
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

34062:AXE82 RS01380
gene id: 34062:AXE82_RS01380
uniprot id: A0A378Q987
names: Function
names: Subunit
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
messages: Homodimer. Part of the PDH complex, consisting of multiple copies of pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

34062:AXE82 RS05570
gene id: 34062:AXE82_RS05570
uniprot id: A0A0X8K656
names: Caution
names: Subcellular Location Annotation
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

34062:AXE82 RS05885
gene id: 34062:AXE82_RS05885
uniprot id: A0A109WGT7
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

34062:AXE82 RS06620
gene id: 34062:AXE82_RS06620
uniprot id: A0A378Q6K3
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

34062:AXE82 RS04090
gene id: 34062:AXE82_RS04090
uniprot id: A0A378Q832
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

34062:AXE82 RS05720
gene id: 34062:AXE82_RS05720
uniprot id: A0A378Q819
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

34062:AXE82 RS04940
gene id: 34062:AXE82_RS04940
uniprot id: A0A378QBX6
names: Similarity
messages: In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.
messages: In the central section; belongs to the CRISPR-associated helicase Cas3 family.

34062:AXE82 RS10565
gene id: 34062:AXE82_RS10565
uniprot id: A0A378QB96
names: Subcellular Location Annotation
messages: Membrane

34062:AXE82 RS04250
gene id: 34062:AXE82_RS04250
uniprot id: A0A0X8K5R3
names: Similarity
messages: Belongs to the UPF0758 family.

34062:AXE82 RS05895
gene id: 34062:AXE82_RS05895
uniprot id: A0A378Q8L2
names: Similarity
messages: Belongs to the peptidase S41A family.

34062:AXE82 RS03855
gene id: 34062:AXE82_RS03855
uniprot id: A0A378Q8T8
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

34062:AXE82 RS03920
gene id: 34062:AXE82_RS03920
uniprot id: A0A120KQV1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

34062:AXE82 RS00385
gene id: 34062:AXE82_RS00385
uniprot id: A0A378Q9T7
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

34062:AXE82 RS11690
gene id: 34062:AXE82_RS11690
uniprot id: A0A120KRB2
names: Similarity
messages: Belongs to the site-specific recombinase resolvase family.

34062:AXE82 RS07715
gene id: 34062:AXE82_RS07715
uniprot id: A0A378QCC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0756 family.
messages: Cell membrane

34062:AXE82 RS10885
gene id: 34062:AXE82_RS10885
uniprot id: A0A0X8K8Q1
names: Similarity
messages: Belongs to the transposase 7 family.

34062:AXE82 RS00005
gene id: 34062:AXE82_RS00005
uniprot id: A0A378QBW4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Catalyzes the deamination of dCTP to dUTP.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

34062:AXE82 RS05745
gene id: 34062:AXE82_RS05745
uniprot id: A0A0X8K683
names: Similarity
messages: Belongs to the prokaryotic GSH synthase family.

34062:AXE82 RS02280
gene id: 34062:AXE82_RS02280
uniprot id: A0A378QA07
names: Similarity
messages: Belongs to the peptidase S41A family.

34062:AXE82 RS07045
gene id: 34062:AXE82_RS07045
uniprot id: A0A109WBV0
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

34062:AXE82 RS09385
gene id: 34062:AXE82_RS09385
uniprot id: A0A378QB65
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

34062:AXE82 RS07330
gene id: 34062:AXE82_RS07330
uniprot id: A0A378QC07
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.

34062:AXE82 RS05430
gene id: 34062:AXE82_RS05430
uniprot id: A0A0X8K635
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

34062:AXE82 RS02055
gene id: 34062:AXE82_RS02055
uniprot id: A0A378QAQ3
names: Function
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.

34062:AXE82 RS01090
gene id: 34062:AXE82_RS01090
uniprot id: A0A109WGB1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbD/TolR family.
messages: Cell inner membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

34062:AXE82 RS02360
gene id: 34062:AXE82_RS02360
uniprot id: A0A378Q901
names: Function
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
messages: Catalyzes two reactions in de novo purine nucleotide biosynthesis. Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate.

34062:AXE82 RS05295
gene id: 34062:AXE82_RS05295
uniprot id: A0A378Q765
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.
messages: Cell membrane
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

34062:AXE82 RS03720
gene id: 34062:AXE82_RS03720
uniprot id: A0A378Q988
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0382 family.
messages: Membrane

34062:AXE82 RS06660
gene id: 34062:AXE82_RS06660
uniprot id: A0A378Q6H2
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

34062:AXE82 RS00800
gene id: 34062:AXE82_RS00800
uniprot id: A0A0X8K4M7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

34062:AXE82 RS04525
gene id: 34062:AXE82_RS04525
uniprot id: A0A378Q8R9
names: Function
names: Similarity
messages: Belongs to the MreC family.
messages: Involved in formation and maintenance of cell shape.

34062:AXE82 RS10055
gene id: 34062:AXE82_RS10055
uniprot id: A0A378QAX9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.

34062:AXE82 RS10295
gene id: 34062:AXE82_RS10295
uniprot id: A0A378QBL0
names: Subcellular Location Annotation
messages: Membrane

34062:AXE82 RS08730
gene id: 34062:AXE82_RS08730
uniprot id: A0A378QCE5
names: Subcellular Location Annotation
messages: Membrane

34062:AXE82 RS02915
gene id: 34062:AXE82_RS02915
uniprot id: A0A120KQT9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

34062:AXE82 RS06930
gene id: 34062:AXE82_RS06930
uniprot id: A0A378Q716
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a(1), b(1), b'(1) and c(9-12).
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

34062:AXE82 RS02445
gene id: 34062:AXE82_RS02445
uniprot id: A0A378Q959
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

34062:AXE82 RS03540
gene id: 34062:AXE82_RS03540
uniprot id: A0A378Q853
names: Subcellular Location Annotation
messages: Membrane

34062:AXE82 RS06690
gene id: 34062:AXE82_RS06690
uniprot id: A0A378Q6R2
names: Similarity
messages: Belongs to the GPAT/DAPAT family.

34062:AXE82 RS02780
gene id: 34062:AXE82_RS02780
uniprot id: A0A378Q9R2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

34062:AXE82 RS02905
gene id: 34062:AXE82_RS02905
uniprot id: A0A109WBK5
names: Function
names: Similarity
messages: Belongs to the transposase 11 family.
messages: Involved in the transposition of the insertion sequence IS5.

34062:AXE82 RS09960
gene id: 34062:AXE82_RS09960
uniprot id: A0A378QAL9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cell membrane
messages: In the C-terminal section; belongs to the complex I 49 kDa subunit family.
messages: In the N-terminal section; belongs to the complex I 30 kDa subunit family.
messages: NDH-1 is composed of 13 different subunits. Subunits NuoB, CD, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

34062:AXE82 RS05125
gene id: 34062:AXE82_RS05125
uniprot id: A0A378Q7M2
names: Similarity
messages: Belongs to the YggT family.

34062:AXE82 RS07990
gene id: 34062:AXE82_RS07990
uniprot id: A0A120KR48
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UreF family.
messages: Cytoplasm
messages: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
messages: UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

34062:AXE82 RS07600
gene id: 34062:AXE82_RS07600
uniprot id: A0A378QDN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbA subfamily.
messages: Periplasm

34062:AXE82 RS10395
gene id: 34062:AXE82_RS10395
uniprot id: A0A378QAA6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.

34062:AXE82 RS01950
gene id: 34062:AXE82_RS01950
uniprot id: A0A378QAS6
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

34062:AXE82 RS08985
gene id: 34062:AXE82_RS08985
uniprot id: A0A0X8K7A5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

34062:AXE82 RS07230
gene id: 34062:AXE82_RS07230
uniprot id: A0A378Q691
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

34062:AXE82 RS11660
gene id: 34062:AXE82_RS11660
uniprot id: A0A378QVU3
names: Similarity
messages: Belongs to the site-specific recombinase resolvase family.

34062:AXE82 RS08435
gene id: 34062:AXE82_RS08435
uniprot id: A0A378QBB3
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

34062:AXE82 RS07060
gene id: 34062:AXE82_RS07060
uniprot id: A0A378Q6J8
names: Similarity
messages: Belongs to the DprA/Smf family.

34062:AXE82 RS04730
gene id: 34062:AXE82_RS04730
uniprot id: A0A0X8K6D9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

34062:AXE82 RS04650
gene id: 34062:AXE82_RS04650
uniprot id: A0A0X8K5V9
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

34062:AXE82 RS00425
gene id: 34062:AXE82_RS00425
uniprot id: A0A378QAD7
names: Similarity
messages: Belongs to the UPF0319 family.

34062:AXE82 RS09285
gene id: 34062:AXE82_RS09285
uniprot id: A0A0X8K7C7
names: Function
names: Similarity
messages: Belongs to the bacterioferritin family.
messages: Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.

34062:AXE82 RS07335
gene id: 34062:AXE82_RS07335
uniprot id: A0A378QBZ1
names: Similarity
messages: Belongs to the IMPACT family.

34062:AXE82 RS07015
gene id: 34062:AXE82_RS07015
uniprot id: A0A378Q6D4
names: Function
names: Similarity
messages: Belongs to the catalase family. HPII subfamily.
messages: Serves to protect cells from the toxic effects of hydrogen peroxide.

34062:AXE82 RS01645
gene id: 34062:AXE82_RS01645
uniprot id: A0A378Q950
names: Caution
names: Function
names: Similarity
messages: Belongs to the precorrin methyltransferase family.
messages: In the C-terminal section; belongs to the precorrin methyltransferase family.
messages: In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme.

34062:AXE82 RS01535
gene id: 34062:AXE82_RS01535
uniprot id: A0A378Q9M8
names: Subcellular Location Annotation
messages: Membrane

34062:AXE82 RS01070
gene id: 34062:AXE82_RS01070
uniprot id: A0A378QA01
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

34062:AXE82 RS02015
gene id: 34062:AXE82_RS02015
uniprot id: A0A378Q9Y0
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

34062:AXE82 RS00215
gene id: 34062:AXE82_RS00215
uniprot id: A0A378QAZ4
names: Subcellular Location Annotation
messages: Membrane

34062:AXE82 RS00400
gene id: 34062:AXE82_RS00400
uniprot id: A0A378Q9U6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

34062:AXE82 RS03910
gene id: 34062:AXE82_RS03910
uniprot id: A0A378Q8D8
names: Function
names: Similarity
messages: Belongs to the ribF family.
messages: Catalyzes the phosphorylation of riboflavin to FMN followed by the adenylation of FMN to FAD.

34062:AXE82 RS05970
gene id: 34062:AXE82_RS05970
uniprot id: A0A109WBP6
names: Function
names: Similarity
names: Subunit
messages: ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.
messages: Belongs to the ParA family. MinD subfamily.
messages: Interacts with MinC and FtsZ.

34062:AXE82 RS05805
gene id: 34062:AXE82_RS05805
uniprot id: A0A120KQY4
names: Similarity
messages: Belongs to the UPF0125 (RnfH) family.

34062:AXE82 RS03850
gene id: 34062:AXE82_RS03850
uniprot id: A0A378QCJ0
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

34062:AXE82 RS00030
gene id: 34062:AXE82_RS00030
uniprot id: A0A378QA14
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

34062:AXE82 RS03645
gene id: 34062:AXE82_RS03645
uniprot id: A0A378Q8B5
names: Subcellular Location Annotation
messages: Membrane

34062:AXE82 RS08340
gene id: 34062:AXE82_RS08340
uniprot id: A0A378QBW8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

34062:AXE82 RS08705
gene id: 34062:AXE82_RS08705
uniprot id: A0A378QBI7
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

34062:AXE82 RS00035
gene id: 34062:AXE82_RS00035
uniprot id: A0A378QAI2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.

34062:AXE82 RS06070
gene id: 34062:AXE82_RS06070
uniprot id: A0A378Q6L1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

34062:AXE82 RS12140
gene id: 34062:AXE82_RS12140
uniprot id: A0A378QVJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autotransporter-2 (AT-2) (TC 1.B.40) family.
messages: Cell surface

34062:AXE82 RS01630
gene id: 34062:AXE82_RS01630
uniprot id: A0A378Q938
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

34062:AXE82 RS09575
gene id: 34062:AXE82_RS09575
uniprot id: A0A378QAP5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

34062:AXE82 RS03130
gene id: 34062:AXE82_RS03130
uniprot id: A0A0X8K5C9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

34062:AXE82 RS09950
gene id: 34062:AXE82_RS09950
uniprot id: A0A378QAI5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

34062:AXE82 RS00710
gene id: 34062:AXE82_RS00710
uniprot id: A0A378QBH8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

34062:AXE82 RS01165
gene id: 34062:AXE82_RS01165
uniprot id: A0A0X8K4R1
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

34062:AXE82 RS01390
gene id: 34062:AXE82_RS01390
uniprot id: A0A0X8K4X3
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

34062:AXE82 RS05640
gene id: 34062:AXE82_RS05640
uniprot id: A0A0X8K6E9
names: Cofactor
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD.
messages: The heme is bound between the two transmembrane subunits.

34062:AXE82 RS09010
gene id: 34062:AXE82_RS09010
uniprot id: A0A378QCV6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

34062:AXE82 RS07270
gene id: 34062:AXE82_RS07270
uniprot id: A0A378QD86
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

34062:AXE82 RS04280
gene id: 34062:AXE82_RS04280
uniprot id: A0A0X8K5Z2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

34062:AXE82 RS08660
gene id: 34062:AXE82_RS08660
uniprot id: A0A378QD27
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

34062:AXE82 RS10215
gene id: 34062:AXE82_RS10215
uniprot id: A0A378QAC7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

34062:AXE82 RS04215
gene id: 34062:AXE82_RS04215
uniprot id: A0A378Q882
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Lacks the C-terminal regulatory region which is replaced by HisZ.

34062:AXE82 RS09350
gene id: 34062:AXE82_RS09350
uniprot id: A0A378QBX0
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

34062:AXE82 RS05080
gene id: 34062:AXE82_RS05080
uniprot id: A0A378Q7M6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

34062:AXE82 RS11080
gene id: 34062:AXE82_RS11080
uniprot id: A0A378QWQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

34062:AXE82 RS04470
gene id: 34062:AXE82_RS04470
uniprot id: A0A378Q8S7
names: Subcellular Location Annotation
messages: Membrane

34062:AXE82 RS04435
gene id: 34062:AXE82_RS04435
uniprot id: A0A0X8K612
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbC subfamily.
messages: Periplasm
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process.

34062:AXE82 RS07410
gene id: 34062:AXE82_RS07410
uniprot id: A0A378QCJ1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Monomer.

34062:AXE82 RS00050
gene id: 34062:AXE82_RS00050
uniprot id: A0A120KQN2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.
messages: Catalyzes the conversion of L-lactate to pyruvate. Is coupled to the respiratory chain.
messages: Cell membrane

34062:AXE82 RS10205
gene id: 34062:AXE82_RS10205
uniprot id: A0A109WC68
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

34062:AXE82 RS10090
gene id: 34062:AXE82_RS10090
uniprot id: A0A378QB16
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

34062:AXE82 RS08325
gene id: 34062:AXE82_RS08325
uniprot id: A0A378QC05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

34062:AXE82 RS08715
gene id: 34062:AXE82_RS08715
uniprot id: A0A378QFT4
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

34062:AXE82 RS01425
gene id: 34062:AXE82_RS01425
uniprot id: A0A378QAG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

34062:AXE82 RS04325
gene id: 34062:AXE82_RS04325
uniprot id: A0A0X8K5S2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

34062:AXE82 RS03795
gene id: 34062:AXE82_RS03795
uniprot id: A0A378Q887
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DyP-type peroxidase family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group non-covalently per subunit.
messages: Homodimer. Part of a ferrous iron transporter composed of EfeU, EfeO and EfeB.
messages: Involved in the recovery of exogenous heme iron. Extracts iron from heme while preserving the protoporphyrin ring intact.
messages: Periplasm

34062:AXE82 RS04530
gene id: 34062:AXE82_RS04530
uniprot id: A0A0X8K5X6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

34062:AXE82 RS10700
gene id: 34062:AXE82_RS10700
uniprot id: A0A378QAG6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Molecular chaperone. Has ATPase activity.

34062:AXE82 RS04385
gene id: 34062:AXE82_RS04385
uniprot id: A0A0X8K5Y5
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: Methylated by PrmB.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

34062:AXE82 RS09515
gene id: 34062:AXE82_RS09515
uniprot id: A0A0X8K7J9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

34062:AXE82 RS00120
gene id: 34062:AXE82_RS00120
uniprot id: A0A378QB86
names: Function
names: Similarity
messages: Belongs to the RlpA family.
messages: Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.

34062:AXE82 RS09635
gene id: 34062:AXE82_RS09635
uniprot id: A0A378QAS7
names: Similarity
messages: Belongs to the glutamate synthase family.

34062:AXE82 RS08605
gene id: 34062:AXE82_RS08605
uniprot id: A0A378QBK8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).

34062:AXE82 RS01430
gene id: 34062:AXE82_RS01430
uniprot id: A0A378Q977
names: Subcellular Location Annotation
messages: Membrane

34062:AXE82 RS04540
gene id: 34062:AXE82_RS04540
uniprot id: A0A378Q7M8
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

34062:AXE82 RS08950
gene id: 34062:AXE82_RS08950
uniprot id: A0A378QB21
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

34062:AXE82 RS06990
gene id: 34062:AXE82_RS06990
uniprot id: A0A0X8K741
names: Similarity
messages: Belongs to the P(II) protein family.

34062:AXE82 RS06120
gene id: 34062:AXE82_RS06120
uniprot id: A0A378Q6K2
names: Caution
names: Function
names: Similarity
messages: Belongs to the Dus family. DusC subfamily.
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U16 in tRNAs.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

34062:AXE82 RS05800
gene id: 34062:AXE82_RS05800
uniprot id: A0A378Q8N4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamE family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

34062:AXE82 RS06975
gene id: 34062:AXE82_RS06975
uniprot id: A0A378QAS0
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

34062:AXE82 RS06165
gene id: 34062:AXE82_RS06165
uniprot id: A0A378Q7S1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

34062:AXE82 RS03695
gene id: 34062:AXE82_RS03695
uniprot id: A0A378Q8A7
names: PTM
messages: Binds 2 heme c groups covalently per subunit.

34062:AXE82 RS08180
gene id: 34062:AXE82_RS08180
uniprot id: A0A378QBZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

34062:AXE82 RS02340
gene id: 34062:AXE82_RS02340
uniprot id: A0A378Q8P7
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

34062:AXE82 RS08575
gene id: 34062:AXE82_RS08575
uniprot id: A0A0X8K8B2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

34062:AXE82 RS00990
gene id: 34062:AXE82_RS00990
uniprot id: A0A378Q9L6
names: Similarity
messages: Belongs to the peptidase S11 family.

34062:AXE82 RS00300
gene id: 34062:AXE82_RS00300
uniprot id: A0A378Q9W1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

34062:AXE82 RS11175
gene id: 34062:AXE82_RS11175
uniprot id: A0A378QVC1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

34062:AXE82 RS08245
gene id: 34062:AXE82_RS08245
uniprot id: A0A378QBY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

34062:AXE82 RS01875
gene id: 34062:AXE82_RS01875
uniprot id: A0A378QA84
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

34062:AXE82 RS09470
gene id: 34062:AXE82_RS09470
uniprot id: A0A378QAR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

34062:AXE82 RS07385
gene id: 34062:AXE82_RS07385
uniprot id: A0A378QBY2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PstS family.
messages: Part of the ABC transporter complex PstSACB involved in phosphate import.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

34062:AXE82 RS02510
gene id: 34062:AXE82_RS02510
uniprot id: A0A378Q8X2
names: Subcellular Location Annotation
messages: Membrane

34062:AXE82 RS01285
gene id: 34062:AXE82_RS01285
uniprot id: A0A378Q9T0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

34062:AXE82 RS11225
gene id: 34062:AXE82_RS11225
uniprot id: A0A378QVG6
names: Similarity
messages: Belongs to the nitroreductase family. HadB/RutE subfamily.

34062:AXE82 RS01480
gene id: 34062:AXE82_RS01480
uniprot id: A0A378Q967
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamD family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

34062:AXE82 RS01530
gene id: 34062:AXE82_RS01530
uniprot id: A0A378Q958
names: Subcellular Location Annotation
messages: Membrane

34062:AXE82 RS06240
gene id: 34062:AXE82_RS06240
uniprot id: A0A109WBR6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

34062:AXE82 RS08320
gene id: 34062:AXE82_RS08320
uniprot id: A0A109WBY4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

34062:AXE82 RS04880
gene id: 34062:AXE82_RS04880
uniprot id: A0A109WBK5
names: Function
names: Similarity
messages: Belongs to the transposase 11 family.
messages: Involved in the transposition of the insertion sequence IS5.

34062:AXE82 RS01030
gene id: 34062:AXE82_RS01030
uniprot id: A0A378Q9G0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

34062:AXE82 RS06840
gene id: 34062:AXE82_RS06840
uniprot id: A0A378Q7E2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Cell membrane
messages: Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system).
messages: Membrane

34062:AXE82 RS03750
gene id: 34062:AXE82_RS03750
uniprot id: A0A378Q9R9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

34062:AXE82 RS02255
gene id: 34062:AXE82_RS02255
uniprot id: A0A378QAK8
names: Subcellular Location Annotation
messages: Cytoplasm

34062:AXE82 RS00455
gene id: 34062:AXE82_RS00455
uniprot id: A0A378QBM3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AFG1 ATPase family. ZapE subfamily.
messages: Cytoplasm
messages: Interacts with FtsZ.
messages: Reduces the stability of FtsZ polymers in the presence of ATP.

34062:AXE82 RS10425
gene id: 34062:AXE82_RS10425
uniprot id: A0A378QEY1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

34062:AXE82 RS01345
gene id: 34062:AXE82_RS01345
uniprot id: A0A378Q9E5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M20A family. DapE subfamily.
messages: Binds 2 Zn(2+) or Co(2+) ions per subunit.
messages: Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
messages: Homodimer.

34062:AXE82 RS06950
gene id: 34062:AXE82_RS06950
uniprot id: A0A378Q6J9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

34062:AXE82 RS11205
gene id: 34062:AXE82_RS11205
uniprot id: A0A0X8K8S4
names: Function
names: Similarity
messages: Belongs to the NtaA/SnaA/DszA monooxygenase family. RutA subfamily.
messages: Catalyzes the pyrimidine ring opening between N-3 and C-4 by an unusual flavin hydroperoxide-catalyzed mechanism, adding oxygen atoms in the process to yield ureidoacrylate peracid, that immediately reacts with FMN forming ureidoacrylate and FMN-N(5)-oxide. The FMN-N(5)-oxide reacts spontaneously with NADH to produce FMN. Requires the flavin reductase RutF to regenerate FMN in vivo.

34062:AXE82 RS04535
gene id: 34062:AXE82_RS04535
uniprot id: A0A378Q811
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

34062:AXE82 RS07435
gene id: 34062:AXE82_RS07435
uniprot id: A0A378QBX2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

34062:AXE82 RS05890
gene id: 34062:AXE82_RS05890
uniprot id: A0A120KQZ2
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

34062:AXE82 RS00705
gene id: 34062:AXE82_RS00705
uniprot id: A0A378Q9Z9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

34062:AXE82 RS11340
gene id: 34062:AXE82_RS11340
uniprot id: A0A378Q9U7
names: Similarity
messages: Belongs to the transposase 8 family.

34062:AXE82 RS05435
gene id: 34062:AXE82_RS05435
uniprot id: A0A378Q7B0
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

34062:AXE82 RS04160
gene id: 34062:AXE82_RS04160
uniprot id: A0A378Q8N3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase II family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.

34062:AXE82 RS06280
gene id: 34062:AXE82_RS06280
uniprot id: A0A378Q6H1
names: Subunit
messages: Homodimer.

34062:AXE82 RS08655
gene id: 34062:AXE82_RS08655
uniprot id: A0A0X8K759
names: Similarity
messages: Belongs to the SAICAR synthetase family.

34062:AXE82 RS03485
gene id: 34062:AXE82_RS03485
uniprot id: A0A378Q868
names: Subcellular Location Annotation
messages: Membrane

34062:AXE82 RS02305
gene id: 34062:AXE82_RS02305
uniprot id: A0A378Q8T4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP J family.
messages: Cell inner membrane
messages: Membrane

34062:AXE82 RS03790
gene id: 34062:AXE82_RS03790
uniprot id: A0A378Q803
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family.
messages: Membrane

34062:AXE82 RS03110
gene id: 34062:AXE82_RS03110
uniprot id: A0A378Q8K6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

34062:AXE82 RS08875
gene id: 34062:AXE82_RS08875
uniprot id: A0A378QCB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

34062:AXE82 RS10240
gene id: 34062:AXE82_RS10240
uniprot id: A0A378QAZ1
names: Subcellular Location Annotation
messages: Membrane

34062:AXE82 RS00680
gene id: 34062:AXE82_RS00680
uniprot id: A0A378QAW4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamA family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

34062:AXE82 RS09440
gene id: 34062:AXE82_RS09440
uniprot id: A0A378QB54
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. PdxB subfamily.
messages: Catalyzes the oxidation of erythronate-4-phosphate to 3-hydroxy-2-oxo-4-phosphonooxybutanoate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

34062:AXE82 RS10140
gene id: 34062:AXE82_RS10140
uniprot id: A0A378QB08
names: Similarity
messages: Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.

34062:AXE82 RS01605
gene id: 34062:AXE82_RS01605
uniprot id: A0A378QAZ9
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD.
messages: Belongs to the RecD family.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding.

34062:AXE82 RS03090
gene id: 34062:AXE82_RS03090
uniprot id: A0A378Q8A6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

34062:AXE82 RS03640
gene id: 34062:AXE82_RS03640
uniprot id: A0A109WBE5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

34062:AXE82 RS09270
gene id: 34062:AXE82_RS09270
uniprot id: A0A378QBD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

34062:AXE82 RS01395
gene id: 34062:AXE82_RS01395
uniprot id: A0A378Q996
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PSRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.

34062:AXE82 RS02605
gene id: 34062:AXE82_RS02605
uniprot id: A0A378Q932
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

34062:AXE82 RS07355
gene id: 34062:AXE82_RS07355
uniprot id: A0A378QD18
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

34062:AXE82 RS08350
gene id: 34062:AXE82_RS08350
uniprot id: A0A378QBD7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.

34062:AXE82 RS01955
gene id: 34062:AXE82_RS01955
uniprot id: A0A378QDJ6
names: Similarity
messages: Belongs to the polysaccharide synthase family.

34062:AXE82 RS00365
gene id: 34062:AXE82_RS00365
uniprot id: A0A378QEH8
names: Similarity
messages: Belongs to the peptidase S49 family.

34062:AXE82 RS02390
gene id: 34062:AXE82_RS02390
uniprot id: A0A378Q8N8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Membrane

34062:AXE82 RS06480
gene id: 34062:AXE82_RS06480
uniprot id: A0A270AT29
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-3 family.
messages: Cytoplasm
messages: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
messages: Monomer.

34062:AXE82 RS11580
gene id: 34062:AXE82_RS11580
uniprot id: A0A378QXA3
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

34062:AXE82 RS05520
gene id: 34062:AXE82_RS05520
uniprot id: A0A378Q7E6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

34062:AXE82 RS01455
gene id: 34062:AXE82_RS01455
uniprot id: A0A109WB64
names: Subcellular Location Annotation
messages: Membrane

34062:AXE82 RS07570
gene id: 34062:AXE82_RS07570
uniprot id: A0A378QD21
names: Function
names: Similarity
messages: Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

34062:AXE82 RS09170
gene id: 34062:AXE82_RS09170
uniprot id: A0A378QAY2
names: Similarity
messages: Belongs to the glutathione peroxidase family.

34062:AXE82 RS09545
gene id: 34062:AXE82_RS09545
uniprot id: A0A0X8K7X5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

34062:AXE82 RS03965
gene id: 34062:AXE82_RS03965
uniprot id: A0A378Q929
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

34062:AXE82 RS08620
gene id: 34062:AXE82_RS08620
uniprot id: A0A378QCB0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase MltG family.
messages: Cell inner membrane
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

34062:AXE82 RS02355
gene id: 34062:AXE82_RS02355
uniprot id: A0A378Q8S1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

34062:AXE82 RS01150
gene id: 34062:AXE82_RS01150
uniprot id: A0A0X8K4W4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YajC family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the SecDF-YidC-YajC translocase complex. The SecDF-YidC-YajC translocase forms a supercomplex with SecYEG, called the holo-translocon (HTL).
messages: The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions.

34062:AXE82 RS09565
gene id: 34062:AXE82_RS09565
uniprot id: A0A378QBB2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

34062:AXE82 RS03890
gene id: 34062:AXE82_RS03890
uniprot id: A0A378Q867
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

34062:AXE82 RS07565
gene id: 34062:AXE82_RS07565
uniprot id: A0A109WBW5
names: Function
names: Similarity
messages: Belongs to the HPPK family.
messages: Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.

34062:AXE82 RS06325
gene id: 34062:AXE82_RS06325
uniprot id: A0A378Q7P2
names: Similarity
messages: Belongs to the OsmC/Ohr family.

34062:AXE82 RS07640
gene id: 34062:AXE82_RS07640
uniprot id: A0A378QBT0
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

34062:AXE82 RS04785
gene id: 34062:AXE82_RS04785
uniprot id: A0A378Q7E3
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.

34062:AXE82 RS02910
gene id: 34062:AXE82_RS02910
uniprot id: A0A0X8K5D8
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

34062:AXE82 RS08215
gene id: 34062:AXE82_RS08215
uniprot id: A0A378QC25
names: Similarity
messages: Belongs to the histone deacetylase family.

34062:AXE82 RS01750
gene id: 34062:AXE82_RS01750
uniprot id: A0A378Q9D4
names: Similarity
messages: Belongs to the DNA/RNA non-specific endonuclease family.

34062:AXE82 RS01015
gene id: 34062:AXE82_RS01015
uniprot id: A0A109WB53
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

34062:AXE82 RS06750
gene id: 34062:AXE82_RS06750
uniprot id: A0A378Q686
names: Cofactor
names: Function
messages: Accepts electrons from ETF and reduces ubiquinone.
messages: Binds 1 [4Fe-4S] cluster.

34062:AXE82 RS04370
gene id: 34062:AXE82_RS04370
uniprot id: A0A0X8K600
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

34062:AXE82 RS06630
gene id: 34062:AXE82_RS06630
uniprot id: A0A378QAZ2
names: Similarity
messages: Belongs to the group II decarboxylase family.

34062:AXE82 RS01940
gene id: 34062:AXE82_RS01940
uniprot id: A0A378Q8Z4
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

34062:AXE82 RS03080
gene id: 34062:AXE82_RS03080
uniprot id: A0A0X8K5D3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

34062:AXE82 RS02930
gene id: 34062:AXE82_RS02930
uniprot id: A0A378Q8X4
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

34062:AXE82 RS08580
gene id: 34062:AXE82_RS08580
uniprot id: A0A378QCH4
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

34062:AXE82 RS07485
gene id: 34062:AXE82_RS07485
uniprot id: A0A378QBW2
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

34062:AXE82 RS03355
gene id: 34062:AXE82_RS03355
uniprot id: A0A378Q8M7
names: Subcellular Location Annotation
messages: Membrane

34062:AXE82 RS05375
gene id: 34062:AXE82_RS05375
uniprot id: A0A378Q7H0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of sn-l,2-diacylglycerol (DAG) to phosphatidic acid. Involved in the recycling of diacylglycerol produced as a by-product during membrane-derived oligosaccharide (MDO) biosynthesis.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

34062:AXE82 RS03285
gene id: 34062:AXE82_RS03285
uniprot id: A0A378Q953
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

34062:AXE82 RS00505
gene id: 34062:AXE82_RS00505
uniprot id: A0A378QBL2
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

34062:AXE82 RS00870
gene id: 34062:AXE82_RS00870
uniprot id: A0A378QAM2
names: Function
names: Similarity
messages: Belongs to the nucleoside phosphorylase PpnP family.
messages: Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions.

34062:AXE82 RS10330
gene id: 34062:AXE82_RS10330
uniprot id: A0A378QF01
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

34062:AXE82 RS03735
gene id: 34062:AXE82_RS03735
uniprot id: A0A378Q827
names: Similarity
messages: Belongs to the sigma-54 factor family.

34062:AXE82 RS09560
gene id: 34062:AXE82_RS09560
uniprot id: A0A378QBS7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

34062:AXE82 RS06085
gene id: 34062:AXE82_RS06085
uniprot id: A0A0X8K6C4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

34062:AXE82 RS03075
gene id: 34062:AXE82_RS03075
uniprot id: A0A378Q992
names: Similarity
messages: Belongs to the intimin/invasin family.

34062:AXE82 RS03230
gene id: 34062:AXE82_RS03230
uniprot id: A0A378Q8R0
names: Similarity
messages: Belongs to the ArsC family.

34062:AXE82 RS09345
gene id: 34062:AXE82_RS09345
uniprot id: A0A378QFH4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

34062:AXE82 RS05120
gene id: 34062:AXE82_RS05120
uniprot id: A0A378Q829
names: Subcellular Location Annotation
messages: Membrane

34062:AXE82 RS01690
gene id: 34062:AXE82_RS01690
uniprot id: A0A378Q972
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XseA family.
messages: Cytoplasm

34062:AXE82 RS06255
gene id: 34062:AXE82_RS06255
uniprot id: A0A378Q8C6
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

34062:AXE82 RS02765
gene id: 34062:AXE82_RS02765
uniprot id: A0A0X8K5D7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecB family.
messages: Cytoplasm
messages: Homotetramer, a dimer of dimers. One homotetramer interacts with 1 SecA dimer.
messages: One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.

34062:AXE82 RS09220
gene id: 34062:AXE82_RS09220
uniprot id: A0A378QBE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Membrane

34062:AXE82 RS06635
gene id: 34062:AXE82_RS06635
uniprot id: A0A378Q777
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

34062:AXE82 RS05250
gene id: 34062:AXE82_RS05250
uniprot id: A0A0X8K831
names: Caution
names: Similarity
messages: Belongs to the fabD family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

34062:AXE82 RS03040
gene id: 34062:AXE82_RS03040
uniprot id: A0A0X8K5G7
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit A family.

34062:AXE82 RS02860
gene id: 34062:AXE82_RS02860
uniprot id: A0A378Q8H5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Monomer.
messages: Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.

34062:AXE82 RS06935
gene id: 34062:AXE82_RS06935
uniprot id: A0A378Q6L7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

34062:AXE82 RS02180
gene id: 34062:AXE82_RS02180
uniprot id: A0A378Q9A5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbE subfamily.
messages: Cell inner membrane

34062:AXE82 RS08375
gene id: 34062:AXE82_RS08375
uniprot id: A0A378QBZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell inner membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

34062:AXE82 RS10285
gene id: 34062:AXE82_RS10285
uniprot id: A0A378QBF0
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

34062:AXE82 RS05475
gene id: 34062:AXE82_RS05475
uniprot id: A0A378Q734
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

34062:AXE82 RS00655
gene id: 34062:AXE82_RS00655
uniprot id: A0A0X8K4Q1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

34062:AXE82 RS04330
gene id: 34062:AXE82_RS04330
uniprot id: A0A109WBI8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

34062:AXE82 RS04275
gene id: 34062:AXE82_RS04275
uniprot id: A0A0X8K5T1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

34062:AXE82 RS01145
gene id: 34062:AXE82_RS01145
uniprot id: A0A0X8K592
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

34062:AXE82 RS02065
gene id: 34062:AXE82_RS02065
uniprot id: A0A378Q9W6
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

34062:AXE82 RS02935
gene id: 34062:AXE82_RS02935
uniprot id: A0A109WBD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

34062:AXE82 RS01695
gene id: 34062:AXE82_RS01695
uniprot id: A0A109WB76
names: Similarity
messages: Belongs to the XseB family.

34062:AXE82 RS02740
gene id: 34062:AXE82_RS02740
uniprot id: A0A378Q906
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

34062:AXE82 RS06720
gene id: 34062:AXE82_RS06720
uniprot id: A0A378Q6J2
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

34062:AXE82 RS07350
gene id: 34062:AXE82_RS07350
uniprot id: A0A378QGJ4
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

34062:AXE82 RS01925
gene id: 34062:AXE82_RS01925
uniprot id: A0A378Q8X7
names: Similarity
messages: Belongs to the UDP-galactopyranose/dTDP-fucopyranose mutase family.

34062:AXE82 RS01795
gene id: 34062:AXE82_RS01795
uniprot id: A0A378Q920
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Belongs to the peroxiredoxin family. Prx6 subfamily.

34062:AXE82 RS08960
gene id: 34062:AXE82_RS08960
uniprot id: A0A120KR40
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

34062:AXE82 RS06405
gene id: 34062:AXE82_RS06405
uniprot id: A0A0X8K6E6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MenA family. Type 1 subfamily.
messages: Cell membrane
messages: Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).
messages: Membrane

34062:AXE82 RS04645
gene id: 34062:AXE82_RS04645
uniprot id: A0A378Q7K7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

34062:AXE82 RS02595
gene id: 34062:AXE82_RS02595
uniprot id: A0A0X8K5E2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

34062:AXE82 RS07260
gene id: 34062:AXE82_RS07260
uniprot id: A0A378QD38
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

34062:AXE82 RS06445
gene id: 34062:AXE82_RS06445
uniprot id: A0A378Q6W0
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

34062:AXE82 RS00745
gene id: 34062:AXE82_RS00745
uniprot id: A0A0X8K4N5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

34062:AXE82 RS05130
gene id: 34062:AXE82_RS05130
uniprot id: A0A378Q8D1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

34062:AXE82 RS04840
gene id: 34062:AXE82_RS04840
uniprot id: A0A378Q7T8
names: Similarity
messages: In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.
messages: In the central section; belongs to the CRISPR-associated helicase Cas3 family.

34062:AXE82 RS00185
gene id: 34062:AXE82_RS00185
uniprot id: A0A378QAF3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.

34062:AXE82 RS00595
gene id: 34062:AXE82_RS00595
uniprot id: A0A378Q9U7
names: Similarity
messages: Belongs to the transposase 8 family.

34062:AXE82 RS05600
gene id: 34062:AXE82_RS05600
uniprot id: A0A378Q7S9
names: Similarity
messages: Belongs to the UDPGP type 2 family.

34062:AXE82 RS10795
gene id: 34062:AXE82_RS10795
uniprot id: A0A0X8K8B6
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

34062:AXE82 RS06945
gene id: 34062:AXE82_RS06945
uniprot id: A0A0X8K6N7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

34062:AXE82 RS09325
gene id: 34062:AXE82_RS09325
uniprot id: A0A120KR73
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

34062:AXE82 RS06110
gene id: 34062:AXE82_RS06110
uniprot id: A0A0X8K6H8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

34062:AXE82 RS07295
gene id: 34062:AXE82_RS07295
uniprot id: A0A109WBU5
names: Similarity
messages: Belongs to the threonine synthase family.

34062:AXE82 RS10340
gene id: 34062:AXE82_RS10340
uniprot id: A0A0X8K7V1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate.
messages: Homotetramer.

34062:AXE82 RS09910
gene id: 34062:AXE82_RS09910
uniprot id: A0A378QAN1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

34062:AXE82 RS04130
gene id: 34062:AXE82_RS04130
uniprot id: A0A378Q7V1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

34062:AXE82 RS07520
gene id: 34062:AXE82_RS07520
uniprot id: A0A378QD34
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LolB family.
messages: Cell outer membrane
messages: Membrane
messages: Monomer.

34062:AXE82 RS08755
gene id: 34062:AXE82_RS08755
uniprot id: A0A378QBH6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

34062:AXE82 RS02330
gene id: 34062:AXE82_RS02330
uniprot id: A0A378Q997
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

34062:AXE82 RS08145
gene id: 34062:AXE82_RS08145
uniprot id: A0A378QBU8
names: Cofactor
names: Function
names: Similarity
messages: Adenine glycosylase active on G-A mispairs. MutY also corrects error-prone DNA synthesis past GO lesions which are due to the oxidatively damaged form of guanine: 7,8-dihydro-8-oxoguanine (8-oxo-dGTP).
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.

34062:AXE82 RS09340
gene id: 34062:AXE82_RS09340
uniprot id: A0A378QCQ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

34062:AXE82 RS05505
gene id: 34062:AXE82_RS05505
uniprot id: A0A0X8K6B4
names: Function
names: Similarity
messages: Belongs to the nucleoside phosphorylase PpnP family.
messages: Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions.

34062:AXE82 RS09160
gene id: 34062:AXE82_RS09160
uniprot id: A0A378QAX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

34062:AXE82 RS09335
gene id: 34062:AXE82_RS09335
uniprot id: A0A109WC28
names: Similarity
messages: Belongs to the glutaredoxin family. Monothiol subfamily.

34062:AXE82 RS04820
gene id: 34062:AXE82_RS04820
uniprot id: A0A378Q8A4
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

34062:AXE82 RS01945
gene id: 34062:AXE82_RS01945
uniprot id: A0A378Q990
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

34062:AXE82 RS04300
gene id: 34062:AXE82_RS04300
uniprot id: A0A378QCA4
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

34062:AXE82 RS06740
gene id: 34062:AXE82_RS06740
uniprot id: A0A378Q6Q2
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

34062:AXE82 RS03665
gene id: 34062:AXE82_RS03665
uniprot id: A0A378Q8I6
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

34062:AXE82 RS10265
gene id: 34062:AXE82_RS10265
uniprot id: A0A0X8K7R1
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

34062:AXE82 RS02855
gene id: 34062:AXE82_RS02855
uniprot id: A0A378Q8I2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

34062:AXE82 RS03955
gene id: 34062:AXE82_RS03955
uniprot id: A0A0X8K5L8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

34062:AXE82 RS05180
gene id: 34062:AXE82_RS05180
uniprot id: A0A378Q8C2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmC/CycZ/HelC family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

34062:AXE82 RS07915
gene id: 34062:AXE82_RS07915
uniprot id: A0A378QG87
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

34062:AXE82 RS07055
gene id: 34062:AXE82_RS07055
uniprot id: A0A378Q6Z5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family. TsaC subfamily.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate.

34062:AXE82 RS04245
gene id: 34062:AXE82_RS04245
uniprot id: A0A378Q7Z7
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

34062:AXE82 RS10470
gene id: 34062:AXE82_RS10470
uniprot id: A0A378QC35
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

34062:AXE82 RS07305
gene id: 34062:AXE82_RS07305
uniprot id: A0A378QD28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

34062:AXE82 RS06940
gene id: 34062:AXE82_RS06940
uniprot id: A0A109WBT1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

34062:AXE82 RS03830
gene id: 34062:AXE82_RS03830
uniprot id: A0A109WBF9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

34062:AXE82 RS01865
gene id: 34062:AXE82_RS01865
uniprot id: A0A378QA12
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

34062:AXE82 RS10760
gene id: 34062:AXE82_RS10760
uniprot id: A0A109WC89
names: Subcellular Location Annotation
messages: Cytoplasm

34062:AXE82 RS01405
gene id: 34062:AXE82_RS01405
uniprot id: A0A378QB42
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.

34062:AXE82 RS09995
gene id: 34062:AXE82_RS09995
uniprot id: A0A0X8K7R3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

34062:AXE82 RS02750
gene id: 34062:AXE82_RS02750
uniprot id: A0A378Q8J4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

34062:AXE82 RS00290
gene id: 34062:AXE82_RS00290
uniprot id: A0A378QAD0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
messages: Homotetramer.

34062:AXE82 RS08030
gene id: 34062:AXE82_RS08030
uniprot id: A0A378QBJ5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

34062:AXE82 RS10220
gene id: 34062:AXE82_RS10220
uniprot id: A0A0X8K7W9
names: Function
names: Similarity
messages: Belongs to the Ap4A hydrolase family.
messages: Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.

34062:AXE82 RS08525
gene id: 34062:AXE82_RS08525
uniprot id: A0A378QBW7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

34062:AXE82 RS06550
gene id: 34062:AXE82_RS06550
uniprot id: A0A378Q6C1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: In the N-terminal section; belongs to the FGAMS family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.

34062:AXE82 RS05480
gene id: 34062:AXE82_RS05480
uniprot id: A0A378Q727
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HemJ family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Catalyzes the oxidation of protoporphyrinogen IX to protoporphyrin IX.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

34062:AXE82 RS04800
gene id: 34062:AXE82_RS04800
uniprot id: A0A378Q7G1
names: Similarity
messages: Belongs to the ArsC family.

34062:AXE82 RS04545
gene id: 34062:AXE82_RS04545
uniprot id: A0A378Q7M3
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

34062:AXE82 RS08285
gene id: 34062:AXE82_RS08285
uniprot id: A0A378QCN9
names: Similarity
messages: Belongs to the glutamate synthase family.

34062:AXE82 RS08280
gene id: 34062:AXE82_RS08280
uniprot id: A0A378QC15
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

34062:AXE82 RS04080
gene id: 34062:AXE82_RS04080
uniprot id: A0A378Q7V9
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TtcA family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is chelated by three Cys residues, the fourth Fe has a free coordination site that may bind a sulfur atom transferred from the persulfide of IscS.
messages: Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
messages: Cytoplasm
messages: Homodimer.
messages: The thiolation reaction likely consists of two steps: a first activation step by ATP to form an adenylated intermediate of the target base of tRNA, and a second nucleophilic substitution step of the sulfur (S) atom supplied by the hydrosulfide attached to the Fe-S cluster.

34062:AXE82 RS04405
gene id: 34062:AXE82_RS04405
uniprot id: A0A378Q8I7
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

34062:AXE82 RS00910
gene id: 34062:AXE82_RS00910
uniprot id: A0A378QE71
names: Similarity
messages: Belongs to the GARS family.

34062:AXE82 RS01025
gene id: 34062:AXE82_RS01025
uniprot id: A0A378QAP3
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

34062:AXE82 RS03185
gene id: 34062:AXE82_RS03185
uniprot id: A0A0X8K5E3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family.
messages: Cell inner membrane
messages: Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.
messages: The complex is composed of two ATP-binding proteins (LolD) and two transmembrane proteins (LolC and LolE).

34062:AXE82 RS01190
gene id: 34062:AXE82_RS01190
uniprot id: A0A0X8K7W6
names: Similarity
messages: Belongs to the HesB/IscA family.

34062:AXE82 RS02385
gene id: 34062:AXE82_RS02385
uniprot id: A0A378Q9Y5
names: Similarity
messages: Belongs to the peptidase M1 family.

34062:AXE82 RS01275
gene id: 34062:AXE82_RS01275
uniprot id: A0A378QAJ3
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

34062:AXE82 RS11405
gene id: 34062:AXE82_RS11405
uniprot id: A0A109WHG8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

34062:AXE82 RS08845
gene id: 34062:AXE82_RS08845
uniprot id: A0A378QB41
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

34062:AXE82 RS10380
gene id: 34062:AXE82_RS10380
uniprot id: A0A109WC71
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

34062:AXE82 RS05240
gene id: 34062:AXE82_RS05240
uniprot id: A0A109WBL6
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

34062:AXE82 RS11410
gene id: 34062:AXE82_RS11410
uniprot id: A0A120KRC0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatB family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

34062:AXE82 RS10410
gene id: 34062:AXE82_RS10410
uniprot id: A0A378QA94
names: Similarity
messages: Belongs to the peptidase S66 family.

34062:AXE82 RS09080
gene id: 34062:AXE82_RS09080
uniprot id: A0A0X8K7I4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

34062:AXE82 RS00975
gene id: 34062:AXE82_RS00975
uniprot id: A0A378QAQ1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxH family.
messages: Binds 2 Mn(2+) ions per subunit in a binuclear metal center.
messages: Cell inner membrane
messages: Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

34062:AXE82 RS07170
gene id: 34062:AXE82_RS07170
uniprot id: A0A0X8K6X6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

34062:AXE82 RS10085
gene id: 34062:AXE82_RS10085
uniprot id: A0A0X8K7P4
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

34062:AXE82 RS03975
gene id: 34062:AXE82_RS03975
uniprot id: A0A378Q8B1
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 2 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

34062:AXE82 RS06570
gene id: 34062:AXE82_RS06570
uniprot id: A0A0X8K6J3
names: Similarity
names: Subunit
messages: Belongs to the MoaE family.
messages: Heterotetramer of 2 MoaD subunits and 2 MoaE subunits. Also stable as homodimer. The enzyme changes between these two forms during catalysis.

34062:AXE82 RS02680
gene id: 34062:AXE82_RS02680
uniprot id: A0A378Q927
names: Similarity
messages: Belongs to the ClpA/ClpB family.

34062:AXE82 RS04200
gene id: 34062:AXE82_RS04200
uniprot id: A0A378Q9J7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lipase chaperone family.
messages: Cell inner membrane
messages: May be involved in the folding of the extracellular lipase during its passage through the periplasm.

34062:AXE82 RS09505
gene id: 34062:AXE82_RS09505
uniprot id: A0A0X8K7H0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

34062:AXE82 RS00970
gene id: 34062:AXE82_RS00970
uniprot id: A0A378QA21
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Homodimer.

34062:AXE82 RS10705
gene id: 34062:AXE82_RS10705
uniprot id: A0A378QBY9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

34062:AXE82 RS09810
gene id: 34062:AXE82_RS09810
uniprot id: A0A378QAK9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I fumarase family.
messages: Catalyzes the reversible hydration of fumarate to (S)-malate.
messages: Homodimer.

34062:AXE82 RS11200
gene id: 34062:AXE82_RS11200
uniprot id: A0A0X8K8G7
names: Function
names: Similarity
messages: Belongs to the isochorismatase family. RutB subfamily.
messages: Hydrolyzes ureidoacrylate to form aminoacrylate and carbamate. The carbamate hydrolyzes spontaneously, thereby releasing one of the nitrogen atoms of the pyrimidine ring as ammonia and one of its carbon atoms as CO2.

34062:AXE82 RS08910
gene id: 34062:AXE82_RS08910
uniprot id: A0A378QCX8
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

34062:AXE82 RS02970
gene id: 34062:AXE82_RS02970
uniprot id: A0A0X8K5H8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

34062:AXE82 RS06860
gene id: 34062:AXE82_RS06860
uniprot id: A0A378Q693
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptF/LptG family.
messages: Component of the lipopolysaccharide transport and assembly complex. The LptBFG transporter is composed of two ATP-binding proteins (LptB) and two transmembrane proteins (LptF and LptG).
messages: Membrane
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.

34062:AXE82 RS05420
gene id: 34062:AXE82_RS05420
uniprot id: A0A378Q7G8
names: Caution
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

34062:AXE82 RS06190
gene id: 34062:AXE82_RS06190
uniprot id: A0A0X8K6U7
names: Subcellular Location Annotation
messages: Membrane

34062:AXE82 RS07660
gene id: 34062:AXE82_RS07660
uniprot id: A0A0X8K862
names: Caution
names: Similarity
messages: Belongs to the DinB family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

34062:AXE82 RS04805
gene id: 34062:AXE82_RS04805
uniprot id: A0A378Q7Q1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArsB family.
messages: Cell membrane
messages: Involved in arsenical resistance. Thought to form the channel of an arsenite pump.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

34062:AXE82 RS07325
gene id: 34062:AXE82_RS07325
uniprot id: A0A378QCG5
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

34062:AXE82 RS06700
gene id: 34062:AXE82_RS06700
uniprot id: A0A378Q698
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

34062:AXE82 RS04095
gene id: 34062:AXE82_RS04095
uniprot id: A0A109WBH2
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

34062:AXE82 RS02610
gene id: 34062:AXE82_RS02610
uniprot id: A0A1B8PU95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

34062:AXE82 RS04575
gene id: 34062:AXE82_RS04575
uniprot id: A0A378Q804
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily.
messages: Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA.

34062:AXE82 RS11090
gene id: 34062:AXE82_RS11090
uniprot id: A0A378QWI3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

34062:AXE82 RS04150
gene id: 34062:AXE82_RS04150
uniprot id: A0A0X8K5T2
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

34062:AXE82 RS10455
gene id: 34062:AXE82_RS10455
uniprot id: A0A378QAC0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Cell inner membrane
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.

34062:AXE82 RS09990
gene id: 34062:AXE82_RS09990
uniprot id: A0A378QB35
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: Composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

34062:AXE82 RS02050
gene id: 34062:AXE82_RS02050
uniprot id: A0A378Q966
names: Subcellular Location Annotation
messages: Membrane

34062:AXE82 RS03380
gene id: 34062:AXE82_RS03380
uniprot id: A0A378QCS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThrE exporter (TC 2.A.79) family.
messages: Membrane

34062:AXE82 RS01510
gene id: 34062:AXE82_RS01510
uniprot id: A0A0X8K502
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

34062:AXE82 RS10170
gene id: 34062:AXE82_RS10170
uniprot id: A0A0X8K7T3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

34062:AXE82 RS05580
gene id: 34062:AXE82_RS05580
uniprot id: A0A378Q705
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

34062:AXE82 RS00825
gene id: 34062:AXE82_RS00825
uniprot id: A0A378QA48
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

34062:AXE82 RS03140
gene id: 34062:AXE82_RS03140
uniprot id: A0A378Q896
names: Function
names: Similarity
names: Subunit
messages: Belongs to the trans-sulfuration enzymes family. MetZ subfamily.
messages: Catalyzes the formation of L-homocysteine from O-succinyl-L-homoserine (OSHS) and hydrogen sulfide.
messages: Homotetramer.

34062:AXE82 RS03280
gene id: 34062:AXE82_RS03280
uniprot id: A0A378QCU4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZipA family.
messages: Cell inner membrane
messages: Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins.

34062:AXE82 RS01125
gene id: 34062:AXE82_RS01125
uniprot id: A0A0X8K4R5
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

34062:AXE82 RS02270
gene id: 34062:AXE82_RS02270
uniprot id: A0A378Q9Q9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.
messages: Cytoplasm
messages: Homodimer.

34062:AXE82 RS10000
gene id: 34062:AXE82_RS10000
uniprot id: A0A378QAH4
names: Subcellular Location Annotation
messages: Membrane

34062:AXE82 RS09970
gene id: 34062:AXE82_RS09970
uniprot id: A0A378QAW0
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

34062:AXE82 RS04240
gene id: 34062:AXE82_RS04240
uniprot id: A0A0X8K5U1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

34062:AXE82 RS05790
gene id: 34062:AXE82_RS05790
uniprot id: A0A378Q6W5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell inner membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

34062:AXE82 RS05695
gene id: 34062:AXE82_RS05695
uniprot id: A0A0X8K663
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Membrane

34062:AXE82 RS04375
gene id: 34062:AXE82_RS04375
uniprot id: A0A0X8K5V8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

34062:AXE82 RS05085
gene id: 34062:AXE82_RS05085
uniprot id: A0A378Q7A9
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

34062:AXE82 RS06075
gene id: 34062:AXE82_RS06075
uniprot id: A0A378Q725
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

34062:AXE82 RS11020
gene id: 34062:AXE82_RS11020
uniprot id: A0A378QV80
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

34062:AXE82 RS04360
gene id: 34062:AXE82_RS04360
uniprot id: A0A0X8K5X0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

34062:AXE82 RS02985
gene id: 34062:AXE82_RS02985
uniprot id: A0A378Q8C3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

34062:AXE82 RS05185
gene id: 34062:AXE82_RS05185
uniprot id: A0A0X8K669
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmB/CycW/HelB family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

34062:AXE82 RS02030
gene id: 34062:AXE82_RS02030
uniprot id: A0A378Q8V9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

34062:AXE82 RS08685
gene id: 34062:AXE82_RS08685
uniprot id: A0A0X8K755
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

34062:AXE82 RS04585
gene id: 34062:AXE82_RS04585
uniprot id: A0A378Q7I0
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

34062:AXE82 RS01700
gene id: 34062:AXE82_RS01700
uniprot id: A0A378Q9E4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
messages: Cell membrane
messages: Membrane
messages: Transport of potassium into the cell.

34062:AXE82 RS06245
gene id: 34062:AXE82_RS06245
uniprot id: A0A378Q6L9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

34062:AXE82 RS10230
gene id: 34062:AXE82_RS10230
uniprot id: A0A378QF19
names: Similarity
messages: Belongs to the transglycosylase Slt family.

34062:AXE82 RS01035
gene id: 34062:AXE82_RS01035
uniprot id: A0A378Q9X7
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

34062:AXE82 RS03210
gene id: 34062:AXE82_RS03210
uniprot id: A0A378Q8J1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Binds 1 copper ion per subunit, denoted as copper B.
messages: Binds 2 heme groups per subunit, denoted as high- and low-spin.
messages: Membrane

34062:AXE82 RS10935
gene id: 34062:AXE82_RS10935
uniprot id: A0A378QVE2
names: Similarity
messages: Belongs to the site-specific recombinase resolvase family.

34062:AXE82 RS05575
gene id: 34062:AXE82_RS05575
uniprot id: A0A0X8K6D1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

34062:AXE82 RS05230
gene id: 34062:AXE82_RS05230
uniprot id: A0A378Q8B2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

34062:AXE82 RS05140
gene id: 34062:AXE82_RS05140
uniprot id: A0A378Q7L6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

34062:AXE82 RS07085
gene id: 34062:AXE82_RS07085
uniprot id: A0A0X8K6W6
names: Similarity
messages: Belongs to the UPF0234 family.

34062:AXE82 RS08700
gene id: 34062:AXE82_RS08700
uniprot id: A0A120KR36
names: Similarity
messages: Belongs to the PhzF family.

34062:AXE82 RS00450
gene id: 34062:AXE82_RS00450
uniprot id: A0A378Q9S9
names: Cofactor
names: Similarity
messages: Belongs to the nitroreductase family.
messages: Binds 1 FMN per subunit.

34062:AXE82 RS05675
gene id: 34062:AXE82_RS05675
uniprot id: A0A378Q6Z4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Plays an essential role in type IV pili and type II pseudopili formation by proteolytically removing the leader sequence from substrate proteins and subsequently monomethylating the alpha-amino group of the newly exposed N-terminal phenylalanine.

34062:AXE82 RS07245
gene id: 34062:AXE82_RS07245
uniprot id: A0A0X8K6Q7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

34062:AXE82 RS05510
gene id: 34062:AXE82_RS05510
uniprot id: A0A378Q864
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

34062:AXE82 RS03340
gene id: 34062:AXE82_RS03340
uniprot id: A0A378Q8P0
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

34062:AXE82 RS00795
gene id: 34062:AXE82_RS00795
uniprot id: A0A378Q9R5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
messages: This function is generally fulfilled by the C-terminal part of HisG, which is missing in some bacteria such as this one.

34062:AXE82 RS11665
gene id: 34062:AXE82_RS11665
uniprot id: A0A378QVH9
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

34062:AXE82 RS08095
gene id: 34062:AXE82_RS08095
uniprot id: A0A0X8K769
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

34062:AXE82 RS00860
gene id: 34062:AXE82_RS00860
uniprot id: A0A0X8K4P0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

34062:AXE82 RS09930
gene id: 34062:AXE82_RS09930
uniprot id: A0A378QF75
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

34062:AXE82 RS09490
gene id: 34062:AXE82_RS09490
uniprot id: A0A378QB45
names: Similarity
messages: Belongs to the TrpF family.

34062:AXE82 RS06505
gene id: 34062:AXE82_RS06505
uniprot id: A0A378Q6D3
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

34062:AXE82 RS01830
gene id: 34062:AXE82_RS01830
uniprot id: A0A378Q8Z7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

34062:AXE82 RS00520
gene id: 34062:AXE82_RS00520
uniprot id: A0A378QAB4
names: Similarity
messages: Belongs to the HIBADH-related family.

34062:AXE82 RS05530
gene id: 34062:AXE82_RS05530
uniprot id: A0A109WBM9
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

34062:AXE82 RS07395
gene id: 34062:AXE82_RS07395
uniprot id: A0A0X8K6Z1
names: Function
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.
messages: Specifically catalyzes the dephosphorylation of 2-phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress.

34062:AXE82 RS01320
gene id: 34062:AXE82_RS01320
uniprot id: A0A378QAC3
names: Similarity
messages: Belongs to the AlaDH/PNT family.

34062:AXE82 RS03775
gene id: 34062:AXE82_RS03775
uniprot id: A0A378Q7X8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Homohexamer.
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the CobB/CobQ family.
messages: Involved in acetate metabolism.
messages: The N-terminal region seems to be important for proper quaternary structure. The C-terminal region contains the substrate-binding site.

34062:AXE82 RS01770
gene id: 34062:AXE82_RS01770
uniprot id: A0A378Q9K8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.
messages: Membrane

34062:AXE82 RS07120
gene id: 34062:AXE82_RS07120
uniprot id: A0A378Q617
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

34062:AXE82 RS08545
gene id: 34062:AXE82_RS08545
uniprot id: A0A378QBB7
names: Function
names: Similarity
messages: Belongs to the LpxC family.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

34062:AXE82 RS10685
gene id: 34062:AXE82_RS10685
uniprot id: A0A378QAL5
names: Similarity
messages: Belongs to the N-Me-Phe pilin family.

34062:AXE82 RS09255
gene id: 34062:AXE82_RS09255
uniprot id: A0A378QC50
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

34062:AXE82 RS05075
gene id: 34062:AXE82_RS05075
uniprot id: A0A109WBK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Membrane

34062:AXE82 RS08995
gene id: 34062:AXE82_RS08995
uniprot id: A0A378QB37
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

34062:AXE82 RS10255
gene id: 34062:AXE82_RS10255
uniprot id: A0A378QAU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

34062:AXE82 RS02400
gene id: 34062:AXE82_RS02400
uniprot id: A0A0X8K571
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

34062:AXE82 RS00920
gene id: 34062:AXE82_RS00920
uniprot id: A0A378QA28
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

34062:AXE82 RS00815
gene id: 34062:AXE82_RS00815
uniprot id: A0A378QE91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0014 family.
messages: Membrane

34062:AXE82 RS05635
gene id: 34062:AXE82_RS05635
uniprot id: A0A378Q769
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Cell inner membrane
messages: Membrane

34062:AXE82 RS06640
gene id: 34062:AXE82_RS06640
uniprot id: A0A378Q6S2
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

34062:AXE82 RS01370
gene id: 34062:AXE82_RS01370
uniprot id: A0A378Q9U1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

34062:AXE82 RS07255
gene id: 34062:AXE82_RS07255
uniprot id: A0A378QGL2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

34062:AXE82 RS00015
gene id: 34062:AXE82_RS00015
uniprot id: A0A378QB38
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

34062:AXE82 RS00830
gene id: 34062:AXE82_RS00830
uniprot id: A0A378QAT2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

34062:AXE82 RS08460
gene id: 34062:AXE82_RS08460
uniprot id: A0A0X8K7D1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

34062:AXE82 RS04320
gene id: 34062:AXE82_RS04320
uniprot id: A0A109WBI4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

34062:AXE82 RS08165
gene id: 34062:AXE82_RS08165
uniprot id: A0A0X8K733
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell membrane
messages: Membrane

34062:AXE82 RS06195
gene id: 34062:AXE82_RS06195
uniprot id: A0A0X8K6I8
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

34062:AXE82 RS00255
gene id: 34062:AXE82_RS00255
uniprot id: A0A0X8K4N3
names: Subcellular Location Annotation
messages: Cytoplasm

34062:AXE82 RS07080
gene id: 34062:AXE82_RS07080
uniprot id: A0A0X8K6N4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

34062:AXE82 RS04380
gene id: 34062:AXE82_RS04380
uniprot id: A0A0X8K6A3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

34062:AXE82 RS02230
gene id: 34062:AXE82_RS02230
uniprot id: A0A0X8K552
names: Subcellular Location Annotation
messages: Membrane

34062:AXE82 RS04270
gene id: 34062:AXE82_RS04270
uniprot id: A0A109WBH8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

34062:AXE82 RS02700
gene id: 34062:AXE82_RS02700
uniprot id: A0A378Q8M0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

34062:AXE82 RS02640
gene id: 34062:AXE82_RS02640
uniprot id: A0A378Q8J3
names: Similarity
messages: Belongs to the RecJ family.

34062:AXE82 RS06675
gene id: 34062:AXE82_RS06675
uniprot id: A0A109WBS4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

34062:AXE82 RS03055
gene id: 34062:AXE82_RS03055
uniprot id: A0A378Q8L6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase T family.
messages: Binds two Mg(2+) per subunit. The active form of the enzyme binds two Mg(2+) ions in its active site. The first Mg(2+) forms only one salt bridge with the protein.
messages: Homodimer.
messages: Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis.

34062:AXE82 RS02100
gene id: 34062:AXE82_RS02100
uniprot id: A0A378Q957
names: Cofactor
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.

34062:AXE82 RS00060
gene id: 34062:AXE82_RS00060
uniprot id: A0A378QEP0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lactate permease family.
messages: Cell inner membrane
messages: Membrane
messages: Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate.

34062:AXE82 RS01010
gene id: 34062:AXE82_RS01010
uniprot id: A0A378QE47
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.
messages: One is catalytic and the other provides a structural contribution.

34062:AXE82 RS09725
gene id: 34062:AXE82_RS09725
uniprot id: A0A378QFA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein SsuA/TauA family.
messages: Periplasm

34062:AXE82 RS03995
gene id: 34062:AXE82_RS03995
uniprot id: A0A378Q9N2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

34062:AXE82 RS01450
gene id: 34062:AXE82_RS01450
uniprot id: A0A378Q9J2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

34062:AXE82 RS04180
gene id: 34062:AXE82_RS04180
uniprot id: A0A120KQV3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

34062:AXE82 RS08360
gene id: 34062:AXE82_RS08360
uniprot id: A0A378QD87
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

34062:AXE82 RS05150
gene id: 34062:AXE82_RS05150
uniprot id: A0A378Q788
names: Similarity
messages: Belongs to the thioredoxin family.

34062:AXE82 RS07320
gene id: 34062:AXE82_RS07320
uniprot id: A0A378QBZ2
names: Function
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia.

34062:AXE82 RS00840
gene id: 34062:AXE82_RS00840
uniprot id: A0A378QA17
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

34062:AXE82 RS04340
gene id: 34062:AXE82_RS04340
uniprot id: A0A109WBI2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

34062:AXE82 RS08850
gene id: 34062:AXE82_RS08850
uniprot id: A0A378QBF4
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

34062:AXE82 RS05650
gene id: 34062:AXE82_RS05650
uniprot id: A0A378Q7R7
names: Similarity
messages: Belongs to the citrate synthase family.

34062:AXE82 RS08570
gene id: 34062:AXE82_RS08570
uniprot id: A0A0X8K7L8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
messages: Cytoplasm
messages: Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.

34062:AXE82 RS04490
gene id: 34062:AXE82_RS04490
uniprot id: A0A378Q7N2
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

34062:AXE82 RS06415
gene id: 34062:AXE82_RS06415
uniprot id: A0A109WCB6
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

34062:AXE82 RS08805
gene id: 34062:AXE82_RS08805
uniprot id: A0A378QBG3
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

34062:AXE82 RS05615
gene id: 34062:AXE82_RS05615
uniprot id: A0A109WGS5
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

34062:AXE82 RS03825
gene id: 34062:AXE82_RS03825
uniprot id: A0A378Q7X2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

34062:AXE82 RS06100
gene id: 34062:AXE82_RS06100
uniprot id: A0A0X8K6T7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

34062:AXE82 RS10540
gene id: 34062:AXE82_RS10540
uniprot id: A0A378QAA9
names: Subcellular Location Annotation
messages: Membrane

34062:AXE82 RS01000
gene id: 34062:AXE82_RS01000
uniprot id: A0A378Q9S7
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

34062:AXE82 RS03225
gene id: 34062:AXE82_RS03225
uniprot id: A0A378Q963
names: Similarity
messages: Belongs to the CcoP / FixP family.

34062:AXE82 RS09095
gene id: 34062:AXE82_RS09095
uniprot id: A0A378QBK6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

34062:AXE82 RS08625
gene id: 34062:AXE82_RS08625
uniprot id: A0A378QBU4
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

34062:AXE82 RS02650
gene id: 34062:AXE82_RS02650
uniprot id: A0A378Q8L3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane