338969:RFER RS17320
gene id: 338969:RFER_RS17320
uniprot id: Q21SX3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell inner membrane
messages: Self-interacts. Interacts with FtsZ.

338969:RFER RS21400
gene id: 338969:RFER_RS21400
uniprot id: Q21QP2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

338969:RFER RS19895
gene id: 338969:RFER_RS19895
uniprot id: Q21RI2
names: Function
names: Similarity
messages: Belongs to the MreC family.
messages: Involved in formation and maintenance of cell shape.

338969:RFER RS09995
gene id: 338969:RFER_RS09995
uniprot id: Q21X01
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

338969:RFER RS01455
gene id: 338969:RFER_RS01455
uniprot id: Q222K8
names: Subcellular Location Annotation
messages: Membrane

338969:RFER RS07095
gene id: 338969:RFER_RS07095
uniprot id: Q21YK9
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

338969:RFER RS19430
gene id: 338969:RFER_RS19430
uniprot id: Q21RT0
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

338969:RFER RS06325
gene id: 338969:RFER_RS06325
uniprot id: Q21Z08
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

338969:RFER RS08255
gene id: 338969:RFER_RS08255
uniprot id: Q21XZ3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

338969:RFER RS03925
gene id: 338969:RFER_RS03925
uniprot id: Q220L7
names: Subcellular Location Annotation
messages: Membrane

338969:RFER RS10405
gene id: 338969:RFER_RS10405
uniprot id: Q21WS0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

338969:RFER RS16050
gene id: 338969:RFER_RS16050
uniprot id: Q21TM3
names: Subcellular Location Annotation
messages: Membrane

338969:RFER RS22985
gene id: 338969:RFER_RS22985
uniprot id: Q21X49
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

338969:RFER RS03320
gene id: 338969:RFER_RS03320
uniprot id: Q220Y6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

338969:RFER RS03720
gene id: 338969:RFER_RS03720
uniprot id: Q220Q5
names: Subcellular Location Annotation
messages: Membrane

338969:RFER RS09065
gene id: 338969:RFER_RS09065
uniprot id: Q21XI4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.

338969:RFER RS03335
gene id: 338969:RFER_RS03335
uniprot id: Q220Y3
names: Similarity
messages: Belongs to the asparagine synthetase family.

338969:RFER RS00825
gene id: 338969:RFER_RS00825
uniprot id: Q222Y1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

338969:RFER RS13595
gene id: 338969:RFER_RS13595
uniprot id: Q21UZ9
names: Function
names: Similarity
messages: Belongs to the nucleoside phosphorylase PpnP family.
messages: Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions.

338969:RFER RS14705
gene id: 338969:RFER_RS14705
uniprot id: Q21UD5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA gyrase inhibitor YacG family.
messages: Binds 1 zinc ion.
messages: Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.
messages: Interacts with GyrB.

338969:RFER RS04105
gene id: 338969:RFER_RS04105
uniprot id: Q220I1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

338969:RFER RS03815
gene id: 338969:RFER_RS03815
uniprot id: Q220N8
names: Similarity
messages: Belongs to the prokaryotic GSH synthase family.

338969:RFER RS22240
gene id: 338969:RFER_RS22240
uniprot id: Q21Q74
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.

338969:RFER RS13560
gene id: 338969:RFER_RS13560
uniprot id: Q21V06
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Monomer.

338969:RFER RS16465
gene id: 338969:RFER_RS16465
uniprot id: Q21TE2
names: Similarity
messages: Belongs to the UPF0758 family.

338969:RFER RS08190
gene id: 338969:RFER_RS08190
uniprot id: Q21Y04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

338969:RFER RS03990
gene id: 338969:RFER_RS03990
uniprot id: Q220K4
names: Similarity
messages: Belongs to the GSP E family.

338969:RFER RS17815
gene id: 338969:RFER_RS17815
uniprot id: Q21SN2
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

338969:RFER RS16270
gene id: 338969:RFER_RS16270
uniprot id: Q21TI0
names: Similarity
messages: Belongs to the GSP E family.

338969:RFER RS01170
gene id: 338969:RFER_RS01170
uniprot id: Q222R3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

338969:RFER RS20460
gene id: 338969:RFER_RS20460
uniprot id: Q21R69
names: Subcellular Location Annotation
messages: Membrane

338969:RFER RS15080
gene id: 338969:RFER_RS15080
uniprot id: Q21U60
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes.

338969:RFER RS02765
gene id: 338969:RFER_RS02765
uniprot id: Q221J5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Cell inner membrane
messages: FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

338969:RFER RS14640
gene id: 338969:RFER_RS14640
uniprot id: Q21UE8
names: PTM
messages: Binds 2 heme c groups covalently per subunit.

338969:RFER RS13005
gene id: 338969:RFER_RS13005
uniprot id: Q21VB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

338969:RFER RS01715
gene id: 338969:RFER_RS01715
uniprot id: Q222F5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
messages: In the native structure, TdcB is in a dimeric form, whereas in the TdcB-AMP complex, it exists in a tetrameric form (dimer of dimers).
messages: TdcB also dehydrates serine to yield pyruvate via analogous enamine/imine intermediates.

338969:RFER RS09455
gene id: 338969:RFER_RS09455
uniprot id: Q21XA6
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

338969:RFER RS08780
gene id: 338969:RFER_RS08780
uniprot id: Q21XP0
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

338969:RFER RS08510
gene id: 338969:RFER_RS08510
uniprot id: Q21XU2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

338969:RFER RS08700
gene id: 338969:RFER_RS08700
uniprot id: Q21XQ6
names: Subcellular Location Annotation
messages: Membrane

338969:RFER RS18980
gene id: 338969:RFER_RS18980
uniprot id: Q21S18
names: Similarity
messages: Belongs to the bacterial phospholipase C family.

338969:RFER RS02670
gene id: 338969:RFER_RS02670
uniprot id: Q221L4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP K family.
messages: Cell inner membrane

338969:RFER RS19345
gene id: 338969:RFER_RS19345
uniprot id: Q21RU6
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

338969:RFER RS14800
gene id: 338969:RFER_RS14800
uniprot id: Q21UB5
names: Similarity
messages: Belongs to the dGTPase family. Type 2 subfamily.

338969:RFER RS05625
gene id: 338969:RFER_RS05625
uniprot id: Q21ZD9
names: Similarity
messages: Belongs to the thioredoxin family.

338969:RFER RS21430
gene id: 338969:RFER_RS21430
uniprot id: Q21QN5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

338969:RFER RS19405
gene id: 338969:RFER_RS19405
uniprot id: Q21RT5
names: Similarity
messages: Belongs to the skp family.

338969:RFER RS07050
gene id: 338969:RFER_RS07050
uniprot id: Q21YL8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

338969:RFER RS12405
gene id: 338969:RFER_RS12405
uniprot id: Q21VN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

338969:RFER RS03590
gene id: 338969:RFER_RS03590
uniprot id: Q220T1
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

338969:RFER RS05170
gene id: 338969:RFER_RS05170
uniprot id: Q21ZM7
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

338969:RFER RS17795
gene id: 338969:RFER_RS17795
uniprot id: Q21SN6
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

338969:RFER RS12135
gene id: 338969:RFER_RS12135
uniprot id: Q21VT3
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 2 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

338969:RFER RS05945
gene id: 338969:RFER_RS05945
uniprot id: Q21Z83
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

338969:RFER RS01880
gene id: 338969:RFER_RS01880
uniprot id: Q222C2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CitM (TC 2.A.11) transporter family.
messages: Cell membrane
messages: Membrane

338969:RFER RS13105
gene id: 338969:RFER_RS13105
uniprot id: Q21V93
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

338969:RFER RS03485
gene id: 338969:RFER_RS03485
uniprot id: Q220V2
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

338969:RFER RS15915
gene id: 338969:RFER_RS15915
uniprot id: Q21TQ0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

338969:RFER RS16590
gene id: 338969:RFER_RS16590
uniprot id: Q21TB7
names: Subcellular Location Annotation
messages: Membrane

338969:RFER RS06945
gene id: 338969:RFER_RS06945
uniprot id: Q21YN9
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

338969:RFER RS03725
gene id: 338969:RFER_RS03725
uniprot id: Q220Q4
names: Similarity
messages: Belongs to the UPF0235 family.

338969:RFER RS13960
gene id: 338969:RFER_RS13960
uniprot id: Q21UT1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

338969:RFER RS04515
gene id: 338969:RFER_RS04515
uniprot id: Q21ZZ8
names: Subcellular Location Annotation
messages: Membrane

338969:RFER RS19065
gene id: 338969:RFER_RS19065
uniprot id: Q21S02
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.
messages: Homohexamer. Dimer of a homotrimer.

338969:RFER RS09910
gene id: 338969:RFER_RS09910
uniprot id: Q21X17
names: Function
names: Similarity
messages: Belongs to the TrhO family.
messages: Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.

338969:RFER RS02865
gene id: 338969:RFER_RS02865
uniprot id: Q221H5
names: Function
messages: Member of the two-component regulatory system PhoR/PhoB involved in the phosphate regulon genes expression. PhoR may function as a membrane-associated protein kinase that phosphorylates PhoB in response to environmental signals.

338969:RFER RS17355
gene id: 338969:RFER_RS17355
uniprot id: Q21SW7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

338969:RFER RS00460
gene id: 338969:RFER_RS00460
uniprot id: Q223F1
names: Cofactor
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.

338969:RFER RS03105
gene id: 338969:RFER_RS03105
uniprot id: Q221C8
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

338969:RFER RS01730
gene id: 338969:RFER_RS01730
uniprot id: Q222F1
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

338969:RFER RS06420
gene id: 338969:RFER_RS06420
uniprot id: Q21YZ0
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

338969:RFER RS09630
gene id: 338969:RFER_RS09630
uniprot id: Q21X72
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon.

338969:RFER RS07505
gene id: 338969:RFER_RS07505
uniprot id: Q21YC9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

338969:RFER RS04905
gene id: 338969:RFER_RS04905
uniprot id: Q21ZS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

338969:RFER RS17515
gene id: 338969:RFER_RS17515
uniprot id: Q21ST8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

338969:RFER RS10860
gene id: 338969:RFER_RS10860
uniprot id: Q21WI1
names: Similarity
messages: Belongs to the universal stress protein A family.

338969:RFER RS08660
gene id: 338969:RFER_RS08660
uniprot id: Q21XR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

338969:RFER RS19725
gene id: 338969:RFER_RS19725
uniprot id: Q21RM0
names: Cofactor
names: Similarity
messages: Belongs to the arginase family.
messages: Binds 2 manganese ions per subunit.

338969:RFER RS07495
gene id: 338969:RFER_RS07495
uniprot id: Q21YD1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

338969:RFER RS07035
gene id: 338969:RFER_RS07035
uniprot id: Q21YM1
names: Subcellular Location Annotation
messages: Membrane

338969:RFER RS13385
gene id: 338969:RFER_RS13385
uniprot id: Q21V37
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

338969:RFER RS04490
gene id: 338969:RFER_RS04490
uniprot id: Q220A3
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

338969:RFER RS14545
gene id: 338969:RFER_RS14545
uniprot id: Q21UG7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

338969:RFER RS11740
gene id: 338969:RFER_RS11740
uniprot id: Q21W09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

338969:RFER RS16765
gene id: 338969:RFER_RS16765
uniprot id: Q21T82
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

338969:RFER RS09110
gene id: 338969:RFER_RS09110
uniprot id: Q21XH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Cell inner membrane
messages: Membrane

338969:RFER RS00220
gene id: 338969:RFER_RS00220
uniprot id: Q223K2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmC/CycZ/HelC family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

338969:RFER RS07510
gene id: 338969:RFER_RS07510
uniprot id: Q21YC8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

338969:RFER RS06875
gene id: 338969:RFER_RS06875
uniprot id: Q21YQ4
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

338969:RFER RS17140
gene id: 338969:RFER_RS17140
uniprot id: Q21T08
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaved by autocatalysis into a large and a small subunit.
messages: This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide.

338969:RFER RS21415
gene id: 338969:RFER_RS21415
uniprot id: Q21QN8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

338969:RFER RS02910
gene id: 338969:RFER_RS02910
uniprot id: Q221G6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial microcompartment
messages: Belongs to the EutB family.
messages: Binds between the large and small subunits.
messages: Catalyzes the deamination of various vicinal amino-alcohols to oxo compounds. Allows this organism to utilize ethanolamine as the sole source of nitrogen and carbon in the presence of vitamin B12.
messages: The basic unit is a heterodimer which dimerizes to form tetramers. The heterotetramers trimerize; 6 large subunits form a core ring with 6 small subunits projecting outwards.

338969:RFER RS02970
gene id: 338969:RFER_RS02970
uniprot id: Q221F4
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

338969:RFER RS06780
gene id: 338969:RFER_RS06780
uniprot id: Q21YS0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

338969:RFER RS08775
gene id: 338969:RFER_RS08775
uniprot id: Q21XP1
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

338969:RFER RS10910
gene id: 338969:RFER_RS10910
uniprot id: Q21WH1
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

338969:RFER RS00180
gene id: 338969:RFER_RS00180
uniprot id: Q223L0
names: Function
names: Similarity
names: Subunit
messages: ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.
messages: Belongs to the ParA family. MinD subfamily.
messages: Interacts with MinC and FtsZ.

338969:RFER RS18135
gene id: 338969:RFER_RS18135
uniprot id: Q21SG8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the malate synthase family. GlcB subfamily.
messages: Cytoplasm
messages: Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

338969:RFER RS04155
gene id: 338969:RFER_RS04155
uniprot id: Q220H1
names: Similarity
messages: Belongs to the heat shock protein 70 family.

338969:RFER RS13230
gene id: 338969:RFER_RS13230
uniprot id: Q21V69
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Cob(I)alamin adenosyltransferase family.
messages: Cytoplasm
messages: Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids.

338969:RFER RS18875
gene id: 338969:RFER_RS18875
uniprot id: Q21S39
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

338969:RFER RS03570
gene id: 338969:RFER_RS03570
uniprot id: Q220T5
names: Similarity
messages: Belongs to the glucose-6-phosphate 1-epimerase family.

338969:RFER RS08685
gene id: 338969:RFER_RS08685
uniprot id: Q21XQ9
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

338969:RFER RS10870
gene id: 338969:RFER_RS10870
uniprot id: Q21WH9
names: Similarity
messages: Belongs to the band 7/mec-2 family.

338969:RFER RS19600
gene id: 338969:RFER_RS19600
uniprot id: Q21RP5
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

338969:RFER RS12170
gene id: 338969:RFER_RS12170
uniprot id: Q21VS6
names: Function
messages: Acetylation of prosthetic group (2-(5''-phosphoribosyl)-3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase.

338969:RFER RS07125
gene id: 338969:RFER_RS07125
uniprot id: Q21YK3
names: Function
names: Subunit
messages: Binds the second messenger bis-(3'-5') cyclic dimeric guanosine monophosphate (c-di-GMP). Can bind two c-di-GMP molecules per monomer. May play a role in bacterial second-messenger regulated processes. Binding to c-di-GMP induces a conformational change of the C- and N-termini resulting in the exposure of a highly negative surface on one side of the protein to a possible effector protein.
messages: Monomer in both c-di-GMP-bound and free forms.

338969:RFER RS12665
gene id: 338969:RFER_RS12665
uniprot id: Q21VH9
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

338969:RFER RS14250
gene id: 338969:RFER_RS14250
uniprot id: Q21UM4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

338969:RFER RS23115
gene id: 338969:RFER_RS23115
uniprot id: Q21SE4
names: Subcellular Location Annotation
messages: Membrane

338969:RFER RS17860
gene id: 338969:RFER_RS17860
uniprot id: Q21SM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone-like protein H-NS family.
messages: nucleoid

338969:RFER RS03880
gene id: 338969:RFER_RS03880
uniprot id: Q220M5
names: Function
names: Similarity
messages: Belongs to the sigma-54 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

338969:RFER RS16990
gene id: 338969:RFER_RS16990
uniprot id: Q21T38
names: Function
names: Similarity
messages: Belongs to the MurCDEF family. Mpl subfamily.
messages: Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl-meso-diaminopimelate by linking it to UDP-N-acetylmuramate.

338969:RFER RS02545
gene id: 338969:RFER_RS02545
uniprot id: Q221N9
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

338969:RFER RS09810
gene id: 338969:RFER_RS09810
uniprot id: Q21X36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

338969:RFER RS04585
gene id: 338969:RFER_RS04585
uniprot id: Q21ZY6
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

338969:RFER RS14310
gene id: 338969:RFER_RS14310
uniprot id: Q21UL5
names: Similarity
messages: Belongs to the universal stress protein A family.

338969:RFER RS10100
gene id: 338969:RFER_RS10100
uniprot id: Q21WY0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

338969:RFER RS07420
gene id: 338969:RFER_RS07420
uniprot id: Q21YE5
names: Similarity
messages: Belongs to the long-chain O-acyltransferase family.

338969:RFER RS00085
gene id: 338969:RFER_RS00085
uniprot id: Q223I8
names: Similarity
messages: Belongs to the iron-containing alcohol dehydrogenase family.

338969:RFER RS12935
gene id: 338969:RFER_RS12935
uniprot id: Q21VC6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

338969:RFER RS09820
gene id: 338969:RFER_RS09820
uniprot id: Q21X34
names: Function
names: Similarity
messages: Belongs to the Dus family. DusA subfamily.
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs.

338969:RFER RS16745
gene id: 338969:RFER_RS16745
uniprot id: Q21T86
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

338969:RFER RS16495
gene id: 338969:RFER_RS16495
uniprot id: Q21TD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the formate dehydrogenase gamma subunit family.
messages: Membrane

338969:RFER RS19340
gene id: 338969:RFER_RS19340
uniprot id: Q21RU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

338969:RFER RS06595
gene id: 338969:RFER_RS06595
uniprot id: Q21YV5
names: Function
names: Similarity
names: Subunit
messages: Catalyzes the ATP-dependent polymerization of arginine and aspartate to multi-L-arginyl-poly-L-aspartic acid (cyanophycin; a water-insoluble reserve polymer).
messages: Homodimer.
messages: In the C-terminal section; belongs to the MurCDEF family.

338969:RFER RS16975
gene id: 338969:RFER_RS16975
uniprot id: Q21T41
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

338969:RFER RS13345
gene id: 338969:RFER_RS13345
uniprot id: Q21V45
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family. ParE type 1 subfamily.
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

338969:RFER RS11785
gene id: 338969:RFER_RS11785
uniprot id: Q21W00
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

338969:RFER RS10075
gene id: 338969:RFER_RS10075
uniprot id: Q21WY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

338969:RFER RS08680
gene id: 338969:RFER_RS08680
uniprot id: Q21XR0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PEPCase type 1 family.
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
messages: Homotetramer.

338969:RFER RS18140
gene id: 338969:RFER_RS18140
uniprot id: Q21SG7
names: Function
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. S-2-haloalkanoic acid dehalogenase family.
messages: Catalyzes the hydrolytic dehalogenation of small (S)-2-haloalkanoic acids to yield the corresponding (R)-2-hydroxyalkanoic acids.

338969:RFER RS08865
gene id: 338969:RFER_RS08865
uniprot id: Q21XM3
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

338969:RFER RS20975
gene id: 338969:RFER_RS20975
uniprot id: Q21QW8
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

338969:RFER RS11100
gene id: 338969:RFER_RS11100
uniprot id: Q21WD3
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

338969:RFER RS13370
gene id: 338969:RFER_RS13370
uniprot id: Q21V40
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

338969:RFER RS12380
gene id: 338969:RFER_RS12380
uniprot id: Q21VN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

338969:RFER RS15625
gene id: 338969:RFER_RS15625
uniprot id: Q21TV9
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

338969:RFER RS10725
gene id: 338969:RFER_RS10725
uniprot id: Q21WK8
names: Caution
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

338969:RFER RS02960
gene id: 338969:RFER_RS02960
uniprot id: Q221F6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

338969:RFER RS07890
gene id: 338969:RFER_RS07890
uniprot id: Q21Y60
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily.
messages: Binds 1 NADP(+) per subunit.
messages: Catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose.
messages: Contains a large N-terminal NADP-binding domain, and a smaller C-terminal substrate-binding domain.
messages: Homopentamer.

338969:RFER RS07445
gene id: 338969:RFER_RS07445
uniprot id: Q21YE1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

338969:RFER RS05795
gene id: 338969:RFER_RS05795
uniprot id: Q21ZB1
names: Similarity
messages: Belongs to the peptidase S11 family.

338969:RFER RS16085
gene id: 338969:RFER_RS16085
uniprot id: Q21TL6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Essential cell division protein that coordinates cell division and chromosome segregation. The N-terminus is involved in assembly of the cell-division machinery. The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region. Translocation stops specifically at Xer-dif sites, where FtsK interacts with the Xer recombinase, allowing activation of chromosome unlinking by recombination. FtsK orienting polar sequences (KOPS) guide the direction of DNA translocation. FtsK can remove proteins from DNA as it translocates, but translocation stops specifically at XerCD-dif site, thereby preventing removal of XerC and XerD from dif.
messages: Membrane

338969:RFER RS08050
gene id: 338969:RFER_RS08050
uniprot id: Q21Y29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TamA family.
messages: Cell outer membrane
messages: Membrane

338969:RFER RS20800
gene id: 338969:RFER_RS20800
uniprot id: Q21R00
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

338969:RFER RS20615
gene id: 338969:RFER_RS20615
uniprot id: Q21R37
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

338969:RFER RS19965
gene id: 338969:RFER_RS19965
uniprot id: Q21RG8
names: Similarity
messages: Belongs to the UPF0250 family.

338969:RFER RS17310
gene id: 338969:RFER_RS17310
uniprot id: Q21SX5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 51 family.
messages: Cell inner membrane
messages: Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors.

338969:RFER RS05100
gene id: 338969:RFER_RS05100
uniprot id: Q21ZN9
names: Subcellular Location Annotation
messages: Membrane

338969:RFER RS00165
gene id: 338969:RFER_RS00165
uniprot id: Q223G7
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

338969:RFER RS18830
gene id: 338969:RFER_RS18830
uniprot id: Q21S48
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CheZ family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P).

338969:RFER RS18340
gene id: 338969:RFER_RS18340
uniprot id: Q21SD3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase D family. Cardiolipin synthase subfamily. ClsB sub-subfamily.
messages: Catalyzes the phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
messages: Cell membrane

338969:RFER RS19240
gene id: 338969:RFER_RS19240
uniprot id: Q21RW7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

338969:RFER RS11745
gene id: 338969:RFER_RS11745
uniprot id: Q21W08
names: Similarity
messages: Belongs to the ABC transporter superfamily.

338969:RFER RS08740
gene id: 338969:RFER_RS08740
uniprot id: Q21XP8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YceF subfamily.
messages: Cytoplasm
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes 7-methyl-GTP (m(7)GTP). May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

338969:RFER RS17930
gene id: 338969:RFER_RS17930
uniprot id: Q21SK9
names: Subcellular Location Annotation
messages: Membrane

338969:RFER RS20835
gene id: 338969:RFER_RS20835
uniprot id: Q21QZ4
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

338969:RFER RS11070
gene id: 338969:RFER_RS11070
uniprot id: Q21WD9
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PSRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.

338969:RFER RS21270
gene id: 338969:RFER_RS21270
uniprot id: Q21QR6
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

338969:RFER RS16360
gene id: 338969:RFER_RS16360
uniprot id: Q21TG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

338969:RFER RS12940
gene id: 338969:RFER_RS12940
uniprot id: Q21VC5
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

338969:RFER RS01450
gene id: 338969:RFER_RS01450
uniprot id: Q222K9
names: Subcellular Location Annotation
messages: Membrane

338969:RFER RS07920
gene id: 338969:RFER_RS07920
uniprot id: Q21Y54
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

338969:RFER RS08995
gene id: 338969:RFER_RS08995
uniprot id: Q21XJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

338969:RFER RS07585
gene id: 338969:RFER_RS07585
uniprot id: Q21YB4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell inner membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

338969:RFER RS09880
gene id: 338969:RFER_RS09880
uniprot id: Q21X23
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class II aldolase/RraA-like family.
messages: Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions (By similarity).
messages: Divalent metal cation.
messages: Homotrimer.

338969:RFER RS10595
gene id: 338969:RFER_RS10595
uniprot id: Q21WN2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

338969:RFER RS14515
gene id: 338969:RFER_RS14515
uniprot id: Q21UH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

338969:RFER RS05175
gene id: 338969:RFER_RS05175
uniprot id: Q21ZM6
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

338969:RFER RS17540
gene id: 338969:RFER_RS17540
uniprot id: Q21ST3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane

338969:RFER RS10785
gene id: 338969:RFER_RS10785
uniprot id: Q21WJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

338969:RFER RS14890
gene id: 338969:RFER_RS14890
uniprot id: Q21U97
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Lacks the C-terminal regulatory region which is replaced by HisZ.

338969:RFER RS20100
gene id: 338969:RFER_RS20100
uniprot id: Q21RE1
names: Similarity
messages: Belongs to the UPF0225 family.

338969:RFER RS05790
gene id: 338969:RFER_RS05790
uniprot id: Q21ZB2
names: Subcellular Location Annotation
messages: Membrane

338969:RFER RS17350
gene id: 338969:RFER_RS17350
uniprot id: Q21SW8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. FtsW subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell division.

338969:RFER RS01120
gene id: 338969:RFER_RS01120
uniprot id: Q222S4
names: Subunit
messages: Homodimer.

338969:RFER RS19615
gene id: 338969:RFER_RS19615
uniprot id: Q21RP2
names: Similarity
messages: Belongs to the DprA/Smf family.

338969:RFER RS10495
gene id: 338969:RFER_RS10495
uniprot id: Q21WQ2
names: Similarity
messages: Belongs to the GARS family.

338969:RFER RS14620
gene id: 338969:RFER_RS14620
uniprot id: Q21UF2
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

338969:RFER RS07575
gene id: 338969:RFER_RS07575
uniprot id: Q21YB6
names: Subcellular Location Annotation
messages: Membrane

338969:RFER RS06395
gene id: 338969:RFER_RS06395
uniprot id: Q21YZ5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

338969:RFER RS11280
gene id: 338969:RFER_RS11280
uniprot id: Q21W97
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

338969:RFER RS06225
gene id: 338969:RFER_RS06225
uniprot id: Q21Z30
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

338969:RFER RS01895
gene id: 338969:RFER_RS01895
uniprot id: Q222B9
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

338969:RFER RS10840
gene id: 338969:RFER_RS10840
uniprot id: Q21WI5
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

338969:RFER RS18110
gene id: 338969:RFER_RS18110
uniprot id: Q21SH3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DcuA/DcuB transporter (TC 2.A.13.1) family.
messages: Cell inner membrane
messages: Membrane
messages: Responsible for the transport of C4-dicarboxylates.

338969:RFER RS05550
gene id: 338969:RFER_RS05550
uniprot id: Q21ZF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

338969:RFER RS09410
gene id: 338969:RFER_RS09410
uniprot id: Q21XB5
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

338969:RFER RS09170
gene id: 338969:RFER_RS09170
uniprot id: Q21XG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0394 family.
messages: Membrane

338969:RFER RS18660
gene id: 338969:RFER_RS18660
uniprot id: Q21S72
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

338969:RFER RS10520
gene id: 338969:RFER_RS10520
uniprot id: Q21WP7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

338969:RFER RS04500
gene id: 338969:RFER_RS04500
uniprot id: Q220A1
names: Function
messages: Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP.

338969:RFER RS07990
gene id: 338969:RFER_RS07990
uniprot id: Q21Y41
names: Function
names: Similarity
messages: Belongs to the Dus family. DusB subfamily.
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

338969:RFER RS04795
gene id: 338969:RFER_RS04795
uniprot id: Q21ZU9
names: Subcellular Location Annotation
messages: Membrane

338969:RFER RS00250
gene id: 338969:RFER_RS00250
uniprot id: Q21QL5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

338969:RFER RS06365
gene id: 338969:RFER_RS06365
uniprot id: Q21Z01
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

338969:RFER RS11010
gene id: 338969:RFER_RS11010
uniprot id: Q21WF0
names: Similarity
messages: Belongs to the HesB/IscA family.

338969:RFER RS02980
gene id: 338969:RFER_RS02980
uniprot id: Q221F2
names: PTM
messages: Binds 1 heme group per subunit.

338969:RFER RS18920
gene id: 338969:RFER_RS18920
uniprot id: Q21S30
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

338969:RFER RS16820
gene id: 338969:RFER_RS16820
uniprot id: Q21T71
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

338969:RFER RS20750
gene id: 338969:RFER_RS20750
uniprot id: Q21R10
names: Function
names: Similarity
messages: Belongs to the HypA/HybF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.

338969:RFER RS10110
gene id: 338969:RFER_RS10110
uniprot id: Q21WX8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
messages: Cytoplasm
messages: Homotrimer.
messages: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

338969:RFER RS02050
gene id: 338969:RFER_RS02050
uniprot id: Q221Y8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

338969:RFER RS03255
gene id: 338969:RFER_RS03255
uniprot id: Q220Z9
names: Similarity
messages: Belongs to the TlyA family.

338969:RFER RS10865
gene id: 338969:RFER_RS10865
uniprot id: Q21WI0
names: Subcellular Location Annotation
messages: Membrane

338969:RFER RS17090
gene id: 338969:RFER_RS17090
uniprot id: Q21T18
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UreD family.
messages: Cytoplasm
messages: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
messages: UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

338969:RFER RS16680
gene id: 338969:RFER_RS16680
uniprot id: Q21T99
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia.

338969:RFER RS11735
gene id: 338969:RFER_RS11735
uniprot id: Q21W10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

338969:RFER RS03625
gene id: 338969:RFER_RS03625
uniprot id: Q220S4
names: Subcellular Location Annotation
messages: Membrane

338969:RFER RS07410
gene id: 338969:RFER_RS07410
uniprot id: Q21YE7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

338969:RFER RS08345
gene id: 338969:RFER_RS08345
uniprot id: Q21XX4
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

338969:RFER RS06335
gene id: 338969:RFER_RS06335
uniprot id: Q21Z06
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

338969:RFER RS17265
gene id: 338969:RFER_RS17265
uniprot id: Q21SY4
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

338969:RFER RS09145
gene id: 338969:RFER_RS09145
uniprot id: Q21XG8
names: Cofactor
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.

338969:RFER RS04415
gene id: 338969:RFER_RS04415
uniprot id: Q220B8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

338969:RFER RS15240
gene id: 338969:RFER_RS15240
uniprot id: Q21U27
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiC family.
messages: Cytoplasm
messages: Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway.

338969:RFER RS09105
gene id: 338969:RFER_RS09105
uniprot id: Q21XH6
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

338969:RFER RS18475
gene id: 338969:RFER_RS18475
uniprot id: Q21SA7
names: Subcellular Location Annotation
messages: Membrane

338969:RFER RS11300
gene id: 338969:RFER_RS11300
uniprot id: Q21W93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ElaB/YgaM/YqjD family.
messages: Cell inner membrane
messages: Membrane

338969:RFER RS03130
gene id: 338969:RFER_RS03130
uniprot id: Q221C3
names: Similarity
messages: Belongs to the universal stress protein A family.

338969:RFER RS19350
gene id: 338969:RFER_RS19350
uniprot id: Q21RU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

338969:RFER RS03580
gene id: 338969:RFER_RS03580
uniprot id: Q220T3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RlmJ family.
messages: Monomer.
messages: Specifically methylates the adenine in position 2030 of 23S rRNA.

338969:RFER RS15065
gene id: 338969:RFER_RS15065
uniprot id: Q21U63
names: Similarity
messages: Belongs to the glutamine synthetase family.

338969:RFER RS02025
gene id: 338969:RFER_RS02025
uniprot id: Q221Z3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine.

338969:RFER RS06670
gene id: 338969:RFER_RS06670
uniprot id: Q21YU1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

338969:RFER RS04695
gene id: 338969:RFER_RS04695
uniprot id: Q21ZW5
names: Function
names: Similarity
messages: Belongs to the transposase 11 family.
messages: Involved in the transposition of the insertion sequence IS5.

338969:RFER RS04095
gene id: 338969:RFER_RS04095
uniprot id: Q220I3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

338969:RFER RS07735
gene id: 338969:RFER_RS07735
uniprot id: Q21Y86
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Monomer.

338969:RFER RS13070
gene id: 338969:RFER_RS13070
uniprot id: Q21VA0
names: Subcellular Location Annotation
messages: Membrane

338969:RFER RS09795
gene id: 338969:RFER_RS09795
uniprot id: Q21X39
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Involved in the heme biosynthesis. Catalyzes the anaerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen III to yield the vinyl groups in protoporphyrinogen IX.
messages: Monomer.

338969:RFER RS02275
gene id: 338969:RFER_RS02275
uniprot id: Q221U5
names: Similarity
messages: Belongs to the IlvD/Edd family.

338969:RFER RS07670
gene id: 338969:RFER_RS07670
uniprot id: Q21Y98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane

338969:RFER RS19445
gene id: 338969:RFER_RS19445
uniprot id: Q21RS6
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.

338969:RFER RS00240
gene id: 338969:RFER_RS00240
uniprot id: Q21QL7
names: Similarity
messages: Belongs to the GST superfamily.

338969:RFER RS12975
gene id: 338969:RFER_RS12975
uniprot id: Q21VB8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

338969:RFER RS01075
gene id: 338969:RFER_RS01075
uniprot id: Q222T3
names: Subcellular Location Annotation
messages: Membrane

338969:RFER RS11615
gene id: 338969:RFER_RS11615
uniprot id: Q21W34
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

338969:RFER RS15985
gene id: 338969:RFER_RS15985
uniprot id: Q21TN6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Monomer.

338969:RFER RS21460
gene id: 338969:RFER_RS21460
uniprot id: Q21QM9
names: Similarity
messages: Belongs to the SIS family. GutQ/KpsF subfamily.

338969:RFER RS08415
gene id: 338969:RFER_RS08415
uniprot id: Q21XW1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

338969:RFER RS13200
gene id: 338969:RFER_RS13200
uniprot id: Q21V75
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.

338969:RFER RS19570
gene id: 338969:RFER_RS19570
uniprot id: Q21RQ1
names: Similarity
messages: Belongs to the archease family.

338969:RFER RS15325
gene id: 338969:RFER_RS15325
uniprot id: Q21U10
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

338969:RFER RS01740
gene id: 338969:RFER_RS01740
uniprot id: Q222E9
names: Similarity
messages: Belongs to the glutamine synthetase family.

338969:RFER RS11180
gene id: 338969:RFER_RS11180
uniprot id: Q21WB7
names: Function
names: Subunit
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
messages: Homodimer. Part of the PDH complex, consisting of multiple copies of pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

338969:RFER RS18750
gene id: 338969:RFER_RS18750
uniprot id: Q21S64
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

338969:RFER RS02740
gene id: 338969:RFER_RS02740
uniprot id: Q221K0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliH family.
messages: Cytoplasm
messages: Needed for flagellar regrowth and assembly.

338969:RFER RS07840
gene id: 338969:RFER_RS07840
uniprot id: Q21Y66
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

338969:RFER RS11605
gene id: 338969:RFER_RS11605
uniprot id: Q21W36
names: Function
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflC subfamily.
messages: HflC and HflK could regulate a protease.

338969:RFER RS00125
gene id: 338969:RFER_RS00125
uniprot id: Q223H5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

338969:RFER RS09690
gene id: 338969:RFER_RS09690
uniprot id: Q21X60
names: Similarity
names: Subunit
messages: Belongs to the MoaE family.
messages: Heterotetramer of 2 MoaD subunits and 2 MoaE subunits. Also stable as homodimer. The enzyme changes between these two forms during catalysis.

338969:RFER RS09010
gene id: 338969:RFER_RS09010
uniprot id: Q21XJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein SsuA/TauA family.
messages: Periplasm

338969:RFER RS07675
gene id: 338969:RFER_RS07675
uniprot id: Q21Y97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane

338969:RFER RS12390
gene id: 338969:RFER_RS12390
uniprot id: Q21VN3
names: Subcellular Location Annotation
messages: Membrane

338969:RFER RS07555
gene id: 338969:RFER_RS07555
uniprot id: Q21YC0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

338969:RFER RS09435
gene id: 338969:RFER_RS09435
uniprot id: Q21XB0
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

338969:RFER RS09770
gene id: 338969:RFER_RS09770
uniprot id: Q21X44
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CcoP / FixP family.
messages: Binds 2 heme C groups per subunit.
messages: C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex.
messages: Cell inner membrane
messages: Component of the cbb3-type cytochrome c oxidase.

338969:RFER RS07765
gene id: 338969:RFER_RS07765
uniprot id: Q21Y80
names: Similarity
messages: Belongs to the universal stress protein A family.

338969:RFER RS07060
gene id: 338969:RFER_RS07060
uniprot id: Q21YL6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

338969:RFER RS16845
gene id: 338969:RFER_RS16845
uniprot id: Q21T66
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

338969:RFER RS13090
gene id: 338969:RFER_RS13090
uniprot id: Q21V96
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

338969:RFER RS20755
gene id: 338969:RFER_RS20755
uniprot id: Q21R09
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily.

338969:RFER RS11080
gene id: 338969:RFER_RS11080
uniprot id: Q21WD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

338969:RFER RS11105
gene id: 338969:RFER_RS11105
uniprot id: Q21WD2
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

338969:RFER RS00535
gene id: 338969:RFER_RS00535
uniprot id: Q223D6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

338969:RFER RS05600
gene id: 338969:RFER_RS05600
uniprot id: Q21ZE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

338969:RFER RS09280
gene id: 338969:RFER_RS09280
uniprot id: Q21XE1
names: Subcellular Location Annotation
messages: Membrane

338969:RFER RS04570
gene id: 338969:RFER_RS04570
uniprot id: Q21ZY8
names: Similarity
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.
messages: Membrane

338969:RFER RS06510
gene id: 338969:RFER_RS06510
uniprot id: Q21YX2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.

338969:RFER RS18345
gene id: 338969:RFER_RS18345
uniprot id: Q21SD2
names: Subcellular Location Annotation
messages: Membrane

338969:RFER RS03635
gene id: 338969:RFER_RS03635
uniprot id: Q220S2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COQ7 family.
messages: Binds 2 iron ions per subunit.
messages: Catalyzes the hydroxylation of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol during ubiquinone biosynthesis.
messages: Cell membrane

338969:RFER RS16585
gene id: 338969:RFER_RS16585
uniprot id: Q21TB8
names: Subcellular Location Annotation
messages: Membrane

338969:RFER RS02625
gene id: 338969:RFER_RS02625
uniprot id: Q221M3
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

338969:RFER RS13220
gene id: 338969:RFER_RS13220
uniprot id: Q21V71
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

338969:RFER RS14755
gene id: 338969:RFER_RS14755
uniprot id: Q21UC5
names: Function
names: Similarity
messages: Belongs to the frataxin family.
messages: Involved in iron-sulfur (Fe-S) cluster assembly. May act as a regulator of Fe-S biogenesis.

338969:RFER RS09895
gene id: 338969:RFER_RS09895
uniprot id: Q21QU5
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

338969:RFER RS20985
gene id: 338969:RFER_RS20985
uniprot id: Q21QW6
names: Similarity
messages: Belongs to the cytochrome P450 family.

338969:RFER RS20475
gene id: 338969:RFER_RS20475
uniprot id: Q21R65
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

338969:RFER RS09080
gene id: 338969:RFER_RS09080
uniprot id: Q21XI1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

338969:RFER RS10895
gene id: 338969:RFER_RS10895
uniprot id: Q21WH4
names: Function
names: Similarity
messages: Belongs to the trehalose phosphatase family.
messages: Removes the phosphate from trehalose 6-phosphate to produce free trehalose.

338969:RFER RS22015
gene id: 338969:RFER_RS22015
uniprot id: Q21QB8
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.

338969:RFER RS13860
gene id: 338969:RFER_RS13860
uniprot id: Q21UV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HupC/HyaC/HydC family.
messages: Membrane

338969:RFER RS06430
gene id: 338969:RFER_RS06430
uniprot id: Q21YY8
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

338969:RFER RS05400
gene id: 338969:RFER_RS05400
uniprot id: Q21ZI4
names: Subcellular Location Annotation
messages: Membrane

338969:RFER RS15595
gene id: 338969:RFER_RS15595
uniprot id: Q21TW3
names: Subcellular Location Annotation
messages: Membrane

338969:RFER RS24490
gene id: 338969:RFER_RS24490
uniprot id: Q21ZF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

338969:RFER RS18910
gene id: 338969:RFER_RS18910
uniprot id: Q21S32
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgI family.
messages: Periplasm
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

338969:RFER RS01755
gene id: 338969:RFER_RS01755
uniprot id: Q222E6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
messages: Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD).

338969:RFER RS16080
gene id: 338969:RFER_RS16080
uniprot id: Q21TL7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LolA family.
messages: Monomer.
messages: Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).
messages: Periplasm

338969:RFER RS07560
gene id: 338969:RFER_RS07560
uniprot id: Q21YB9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

338969:RFER RS01500
gene id: 338969:RFER_RS01500
uniprot id: Q222J9
names: Similarity
messages: Belongs to the adrenodoxin/putidaredoxin family.

338969:RFER RS17405
gene id: 338969:RFER_RS17405
uniprot id: Q21SV8
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

338969:RFER RS15890
gene id: 338969:RFER_RS15890
uniprot id: Q21TQ5
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

338969:RFER RS20545
gene id: 338969:RFER_RS20545
uniprot id: Q21R51
names: Similarity
messages: Belongs to the AlaDH/PNT family.

338969:RFER RS17650
gene id: 338969:RFER_RS17650
uniprot id: Q21SR5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

338969:RFER RS17055
gene id: 338969:RFER_RS17055
uniprot id: Q21T25
names: Similarity
messages: Belongs to the peptidase U62 family.

338969:RFER RS06720
gene id: 338969:RFER_RS06720
uniprot id: Q21YT1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

338969:RFER RS17690
gene id: 338969:RFER_RS17690
uniprot id: Q21SQ7
names: Similarity
messages: Belongs to the PrpF family.

338969:RFER RS13250
gene id: 338969:RFER_RS13250
uniprot id: Q21V65
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

338969:RFER RS16730
gene id: 338969:RFER_RS16730
uniprot id: Q21T89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

338969:RFER RS04030
gene id: 338969:RFER_RS04030
uniprot id: Q220J6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

338969:RFER RS14070
gene id: 338969:RFER_RS14070
uniprot id: Q21UQ9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

338969:RFER RS14695
gene id: 338969:RFER_RS14695
uniprot id: Q21UD7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

338969:RFER RS10340
gene id: 338969:RFER_RS10340
uniprot id: Q21WT2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family.
messages: Cytoplasm
messages: Homotrimer.

338969:RFER RS10410
gene id: 338969:RFER_RS10410
uniprot id: Q21WR9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
messages: Homodimer.

338969:RFER RS00930
gene id: 338969:RFER_RS00930
uniprot id: Q222W0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Phosphonates importer (TC 3.A.1.9.1) family.
messages: Cell inner membrane
messages: Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PhnC), two transmembrane proteins (PhnE) and a solute-binding protein (PhnD).

338969:RFER RS13610
gene id: 338969:RFER_RS13610
uniprot id: Q21UZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

338969:RFER RS17105
gene id: 338969:RFER_RS17105
uniprot id: Q21T15
names: Subcellular Location Annotation
messages: Membrane

338969:RFER RS02585
gene id: 338969:RFER_RS02585
uniprot id: Q221N1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDT1 family.
messages: Membrane

338969:RFER RS09640
gene id: 338969:RFER_RS09640
uniprot id: Q21X70
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

338969:RFER RS00655
gene id: 338969:RFER_RS00655
uniprot id: Q223B4
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

338969:RFER RS04245
gene id: 338969:RFER_RS04245
uniprot id: Q220F3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

338969:RFER RS11595
gene id: 338969:RFER_RS11595
uniprot id: Q21W38
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
messages: This function is generally fulfilled by the C-terminal part of HisG, which is missing in some bacteria such as this one.

338969:RFER RS21395
gene id: 338969:RFER_RS21395
uniprot id: Q21QP3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell inner membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

338969:RFER RS20005
gene id: 338969:RFER_RS20005
uniprot id: Q21RG0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

338969:RFER RS08325
gene id: 338969:RFER_RS08325
uniprot id: Q21XX8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

338969:RFER RS20565
gene id: 338969:RFER_RS20565
uniprot id: Q21R47
names: Similarity
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.

338969:RFER RS09665
gene id: 338969:RFER_RS09665
uniprot id: Q21X65
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

338969:RFER RS21605
gene id: 338969:RFER_RS21605
uniprot id: Q21QJ5
names: Similarity
messages: Belongs to the GSP E family.

338969:RFER RS20740
gene id: 338969:RFER_RS20740
uniprot id: Q21R12
names: Similarity
messages: Belongs to the HupF/HypC family.

338969:RFER RS05850
gene id: 338969:RFER_RS05850
uniprot id: Q21ZA0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell inner membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.

338969:RFER RS16830
gene id: 338969:RFER_RS16830
uniprot id: Q21T69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

338969:RFER RS20230
gene id: 338969:RFER_RS20230
uniprot id: Q21RB5
names: Subcellular Location Annotation
messages: Membrane

338969:RFER RS17035
gene id: 338969:RFER_RS17035
uniprot id: Q21T29
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

338969:RFER RS14050
gene id: 338969:RFER_RS14050
uniprot id: Q21UR3
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily.
messages: Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA.

338969:RFER RS11190
gene id: 338969:RFER_RS11190
uniprot id: Q21WB5
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

338969:RFER RS21435
gene id: 338969:RFER_RS21435
uniprot id: Q21QN4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

338969:RFER RS08920
gene id: 338969:RFER_RS08920
uniprot id: Q21XL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic sulfate-binding protein family.
messages: Periplasm

338969:RFER RS07385
gene id: 338969:RFER_RS07385
uniprot id: Q21YF2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

338969:RFER RS10055
gene id: 338969:RFER_RS10055
uniprot id: Q21WY9
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

338969:RFER RS12445
gene id: 338969:RFER_RS12445
uniprot id: Q21VM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

338969:RFER RS14905
gene id: 338969:RFER_RS14905
uniprot id: Q21U94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

338969:RFER RS24435
gene id: 338969:RFER_RS24435
uniprot id: Q221H1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Membrane

338969:RFER RS19490
gene id: 338969:RFER_RS19490
uniprot id: Q21RR6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

338969:RFER RS09375
gene id: 338969:RFER_RS09375
uniprot id: Q21XC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

338969:RFER RS21370
gene id: 338969:RFER_RS21370
uniprot id: Q21QP9
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

338969:RFER RS06675
gene id: 338969:RFER_RS06675
uniprot id: Q21YU0
names: Function
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.
messages: Catalyzes the dephosphorylation of phosphoserine (P-Ser) in vitro. Also catalyzes the dephosphorylation of phosphothreonine (P-Thr) in vitro.

338969:RFER RS08965
gene id: 338969:RFER_RS08965
uniprot id: Q21XK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NlpA lipoprotein family.
messages: Membrane

338969:RFER RS19005
gene id: 338969:RFER_RS19005
uniprot id: Q21S14
names: Function
names: Similarity
messages: Belongs to the cyanase family.
messages: Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide.

338969:RFER RS21440
gene id: 338969:RFER_RS21440
uniprot id: Q21QN3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

338969:RFER RS22045
gene id: 338969:RFER_RS22045
uniprot id: Q21QB1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

338969:RFER RS17205
gene id: 338969:RFER_RS17205
uniprot id: Q21SZ5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease gamma subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

338969:RFER RS07455
gene id: 338969:RFER_RS07455
uniprot id: Q21YD9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

338969:RFER RS09450
gene id: 338969:RFER_RS09450
uniprot id: Q21XA7
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

338969:RFER RS07625
gene id: 338969:RFER_RS07625
uniprot id: Q21YA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

338969:RFER RS07940
gene id: 338969:RFER_RS07940
uniprot id: Q21Y50
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

338969:RFER RS20310
gene id: 338969:RFER_RS20310
uniprot id: Q21R99
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

338969:RFER RS11110
gene id: 338969:RFER_RS11110
uniprot id: Q21WD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

338969:RFER RS10300
gene id: 338969:RFER_RS10300
uniprot id: Q21WU0
names: Subcellular Location Annotation
messages: Cell inner membrane

338969:RFER RS21420
gene id: 338969:RFER_RS21420
uniprot id: Q21QN7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

338969:RFER RS18810
gene id: 338969:RFER_RS18810
uniprot id: Q21S52
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FlhC family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways.
messages: Heterohexamer composed of two FlhC and four FlhD subunits. Each FlhC binds a FlhD dimer, forming a heterotrimer, and a hexamer assembles by dimerization of two heterotrimers.

338969:RFER RS20590
gene id: 338969:RFER_RS20590
uniprot id: Q21R42
names: Subcellular Location Annotation
messages: Membrane

338969:RFER RS11405
gene id: 338969:RFER_RS11405
uniprot id: Q21W73
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.

338969:RFER RS08825
gene id: 338969:RFER_RS08825
uniprot id: Q21XN1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

338969:RFER RS08465
gene id: 338969:RFER_RS08465
uniprot id: Q21XV1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell inner membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

338969:RFER RS11315
gene id: 338969:RFER_RS11315
uniprot id: Q21W90
names: Similarity
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. Type 2 subfamily.

338969:RFER RS12630
gene id: 338969:RFER_RS12630
uniprot id: Q21VI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Membrane

338969:RFER RS11660
gene id: 338969:RFER_RS11660
uniprot id: Q21W25
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.

338969:RFER RS07995
gene id: 338969:RFER_RS07995
uniprot id: Q21Y40
names: Similarity
messages: Belongs to the transcriptional regulatory Fis family.

338969:RFER RS01765
gene id: 338969:RFER_RS01765
uniprot id: Q222E4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

338969:RFER RS06270
gene id: 338969:RFER_RS06270
uniprot id: Q21Z21
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

338969:RFER RS06105
gene id: 338969:RFER_RS06105
uniprot id: Q21Z53
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

338969:RFER RS09510
gene id: 338969:RFER_RS09510
uniprot id: Q21X95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane OOP (TC 1.B.6) superfamily.
messages: Cell outer membrane
messages: Membrane

338969:RFER RS07830
gene id: 338969:RFER_RS07830
uniprot id: Q21Y68
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

338969:RFER RS19875
gene id: 338969:RFER_RS19875
uniprot id: Q21RI6
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

338969:RFER RS07370
gene id: 338969:RFER_RS07370
uniprot id: Q21YF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. DIT1 subfamily.
messages: Membrane

338969:RFER RS04745
gene id: 338969:RFER_RS04745
uniprot id: Q21ZV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

338969:RFER RS13335
gene id: 338969:RFER_RS13335
uniprot id: Q21V47
names: Similarity
messages: Belongs to the HSP15 family.

338969:RFER RS21560
gene id: 338969:RFER_RS21560
uniprot id: Q21QK4
names: Subcellular Location Annotation
messages: Membrane

338969:RFER RS00615
gene id: 338969:RFER_RS00615
uniprot id: Q223C1
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.

338969:RFER RS14950
gene id: 338969:RFER_RS14950
uniprot id: Q21U85
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatB family.
messages: Cell inner membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

338969:RFER RS13145
gene id: 338969:RFER_RS13145
uniprot id: Q21V85
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

338969:RFER RS15210
gene id: 338969:RFER_RS15210
uniprot id: Q21U33
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

338969:RFER RS05380
gene id: 338969:RFER_RS05380
uniprot id: Q21ZI8
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

338969:RFER RS16705
gene id: 338969:RFER_RS16705
uniprot id: Q21T94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

338969:RFER RS21380
gene id: 338969:RFER_RS21380
uniprot id: Q21QP7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

338969:RFER RS19355
gene id: 338969:RFER_RS19355
uniprot id: Q21RU4
names: Similarity
messages: Belongs to the ABC transporter superfamily.

338969:RFER RS15020
gene id: 338969:RFER_RS15020
uniprot id: Q21U72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

338969:RFER RS18960
gene id: 338969:RFER_RS18960
uniprot id: Q21S22
names: Similarity
messages: Belongs to the PhzF family.

338969:RFER RS18125
gene id: 338969:RFER_RS18125
uniprot id: Q21SH0
names: Similarity
messages: Belongs to the DEAD box helicase family.

338969:RFER RS01070
gene id: 338969:RFER_RS01070
uniprot id: Q222T4
names: Subcellular Location Annotation
messages: Membrane

338969:RFER RS06970
gene id: 338969:RFER_RS06970
uniprot id: Q21YN4
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

338969:RFER RS11335
gene id: 338969:RFER_RS11335
uniprot id: Q21W86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

338969:RFER RS11705
gene id: 338969:RFER_RS11705
uniprot id: Q21W16
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

338969:RFER RS00565
gene id: 338969:RFER_RS00565
uniprot id: Q223D0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase A chain family.
messages: Cell inner membrane
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

338969:RFER RS13360
gene id: 338969:RFER_RS13360
uniprot id: Q21V42
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

338969:RFER RS20725
gene id: 338969:RFER_RS20725
uniprot id: Q21R15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

338969:RFER RS15980
gene id: 338969:RFER_RS15980
uniprot id: Q21TN7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

338969:RFER RS09645
gene id: 338969:RFER_RS09645
uniprot id: Q21X69
names: Similarity
messages: Belongs to the PhoH family.

338969:RFER RS06295
gene id: 338969:RFER_RS06295
uniprot id: Q21Z16
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

338969:RFER RS16670
gene id: 338969:RFER_RS16670
uniprot id: Q21TA1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Catalyzes the deamination of dCTP to dUTP.
messages: Homotrimer.

338969:RFER RS06690
gene id: 338969:RFER_RS06690
uniprot id: Q21YT7
names: Function
names: Similarity
messages: Bifunctional enzyme that catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF).
messages: In the C-terminal section; belongs to the IspF family.
messages: In the N-terminal section; belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.

338969:RFER RS02240
gene id: 338969:RFER_RS02240
uniprot id: Q221V2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

338969:RFER RS14500
gene id: 338969:RFER_RS14500
uniprot id: Q21UH6
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

338969:RFER RS07540
gene id: 338969:RFER_RS07540
uniprot id: Q21YC3
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

338969:RFER RS18015
gene id: 338969:RFER_RS18015
uniprot id: Q21SJ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC-2 integral membrane protein family. Lipooligosaccharide exporter (TC 3.A.1.102) subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Part of the ABC transporter complex NodIJ involved in the export of the nodulation factors (Nod factors), the bacterial signal molecules that induce symbiosis and subsequent nodulation induction. Nod factors are LCO (lipo-chitin oligosaccharide), a modified beta-1,4-linked N-acetylglucosamine oligosaccharide. This subunit encodes the transporter.
messages: The complex is composed of two ATP-binding proteins (NodI) and two transmembrane proteins (NodJ).

338969:RFER RS12905
gene id: 338969:RFER_RS12905
uniprot id: Q21VD2
names: Similarity
messages: Belongs to the CmpA/NrtA family.

338969:RFER RS19880
gene id: 338969:RFER_RS19880
uniprot id: Q21RI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

338969:RFER RS18755
gene id: 338969:RFER_RS18755
uniprot id: Q21S63
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

338969:RFER RS09740
gene id: 338969:RFER_RS09740
uniprot id: Q21X50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

338969:RFER RS06200
gene id: 338969:RFER_RS06200
uniprot id: Q21Z35
names: Subcellular Location Annotation
messages: Membrane

338969:RFER RS10440
gene id: 338969:RFER_RS10440
uniprot id: Q21WR3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

338969:RFER RS14830
gene id: 338969:RFER_RS14830
uniprot id: Q21UA9
names: Similarity
messages: Belongs to the glutamate synthase family.

338969:RFER RS17500
gene id: 338969:RFER_RS17500
uniprot id: Q21SU1
names: Subcellular Location Annotation
messages: Membrane

338969:RFER RS18290
gene id: 338969:RFER_RS18290
uniprot id: Q21SE3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

338969:RFER RS02510
gene id: 338969:RFER_RS02510
uniprot id: Q221P6
names: Similarity
messages: Belongs to the long-chain O-acyltransferase family.

338969:RFER RS04385
gene id: 338969:RFER_RS04385
uniprot id: Q220C4
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

338969:RFER RS11090
gene id: 338969:RFER_RS11090
uniprot id: Q21WD5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PriB family.
messages: Binds single-stranded DNA at the primosome assembly site (PAS).
messages: Component of the preprimosomal complex composed of PriA, PriB, PriC, DnaB and DnaT. Upon transient interaction with DnaG it forms the primosome.

338969:RFER RS14945
gene id: 338969:RFER_RS14945
uniprot id: Q21U86
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell inner membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

338969:RFER RS09000
gene id: 338969:RFER_RS09000
uniprot id: Q21XJ7
names: Function
names: Similarity
messages: Belongs to the SsuD family.
messages: Catalyzes the desulfonation of aliphatic sulfonates.

338969:RFER RS02965
gene id: 338969:RFER_RS02965
uniprot id: Q221F5
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

338969:RFER RS12815
gene id: 338969:RFER_RS12815
uniprot id: Q21VF0
names: Similarity
messages: Belongs to the DODA-type extradiol aromatic ring-opening dioxygenase family.

338969:RFER RS06995
gene id: 338969:RFER_RS06995
uniprot id: Q21YM9
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the RuBisCO large chain family. Type II subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site.
messages: The basic functional RuBisCO is composed of a large chain homodimer in a 'head-to-tail' conformation. In contrast to form I RuBisCO, the form II RuBisCO are composed solely of large subunits.

338969:RFER RS10790
gene id: 338969:RFER_RS10790
uniprot id: Q21WJ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

338969:RFER RS00820
gene id: 338969:RFER_RS00820
uniprot id: Q222Y2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

338969:RFER RS11610
gene id: 338969:RFER_RS11610
uniprot id: Q21W35
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. HflK subfamily.
messages: HflC and HflK could encode or regulate a protease.
messages: HflC and HflK may interact to form a multimeric complex.
messages: Membrane

338969:RFER RS12485
gene id: 338969:RFER_RS12485
uniprot id: Q21VL5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).

338969:RFER RS10855
gene id: 338969:RFER_RS10855
uniprot id: Q21WI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

338969:RFER RS16130
gene id: 338969:RFER_RS16130
uniprot id: Q21TK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

338969:RFER RS19245
gene id: 338969:RFER_RS19245
uniprot id: Q21RW6
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

338969:RFER RS10925
gene id: 338969:RFER_RS10925
uniprot id: Q21WG8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgE subfamily.
messages: Homodimer.
messages: Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1->4)-glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB.

338969:RFER RS21405
gene id: 338969:RFER_RS21405
uniprot id: Q21QP0
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

338969:RFER RS09980
gene id: 338969:RFER_RS09980
uniprot id: Q21X03
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
messages: Cytoplasm

338969:RFER RS17525
gene id: 338969:RFER_RS17525
uniprot id: Q21ST6
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

338969:RFER RS04980
gene id: 338969:RFER_RS04980
uniprot id: Q21ZR2
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

338969:RFER RS15100
gene id: 338969:RFER_RS15100
uniprot id: Q21U56
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

338969:RFER RS16600
gene id: 338969:RFER_RS16600
uniprot id: Q21TB5
names: Subcellular Location Annotation
messages: Membrane

338969:RFER RS09035
gene id: 338969:RFER_RS09035
uniprot id: Q21XJ0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

338969:RFER RS00625
gene id: 338969:RFER_RS00625
uniprot id: Q223B9
names: Subcellular Location Annotation
messages: Membrane

338969:RFER RS14885
gene id: 338969:RFER_RS14885
uniprot id: Q21U98
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm

338969:RFER RS08030
gene id: 338969:RFER_RS08030
uniprot id: Q21Y33
names: PTM
messages: Binds 2 heme c groups covalently per subunit.

338969:RFER RS09045
gene id: 338969:RFER_RS09045
uniprot id: Q21XI8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

338969:RFER RS02550
gene id: 338969:RFER_RS02550
uniprot id: Q221N8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.

338969:RFER RS00145
gene id: 338969:RFER_RS00145
uniprot id: Q223H1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

338969:RFER RS06915
gene id: 338969:RFER_RS06915
uniprot id: Q21YP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

338969:RFER RS08980
gene id: 338969:RFER_RS08980
uniprot id: Q21XK1
names: Similarity
messages: Belongs to the NtaA/SnaA/DszA monooxygenase family.

338969:RFER RS20995
gene id: 338969:RFER_RS20995
uniprot id: Q21QW4
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

338969:RFER RS19670
gene id: 338969:RFER_RS19670
uniprot id: Q21RN1
names: Similarity
messages: Belongs to the UPF0102 family.

338969:RFER RS01800
gene id: 338969:RFER_RS01800
uniprot id: Q222D7
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Clade 'B2' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
messages: Cytoplasm
messages: Homodimer.
messages: Non-allosteric.

338969:RFER RS07205
gene id: 338969:RFER_RS07205
uniprot id: Q21YI7
names: Function
names: Similarity
messages: Belongs to the ribF family.
messages: Catalyzes the phosphorylation of riboflavin to FMN followed by the adenylation of FMN to FAD.

338969:RFER RS04040
gene id: 338969:RFER_RS04040
uniprot id: Q220J4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
messages: Belongs to the azoreductase type 1 family.
messages: Binds 1 FMN per subunit.
messages: Homodimer.
messages: Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones.

338969:RFER RS18930
gene id: 338969:RFER_RS18930
uniprot id: Q21S28
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

338969:RFER RS13635
gene id: 338969:RFER_RS13635
uniprot id: Q21UZ1
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

338969:RFER RS19015
gene id: 338969:RFER_RS19015
uniprot id: Q21S12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

338969:RFER RS08990
gene id: 338969:RFER_RS08990
uniprot id: Q21XJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Aliphatic sulfonates importer (TC 3.A.1.17.2) family.
messages: Cell inner membrane
messages: Part of the ABC transporter complex SsuABC involved in aliphatic sulfonates import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (SsuB), two transmembrane proteins (SsuC) and a solute-binding protein (SsuA).

338969:RFER RS16970
gene id: 338969:RFER_RS16970
uniprot id: Q21T42
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

338969:RFER RS17550
gene id: 338969:RFER_RS17550
uniprot id: Q21ST1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

338969:RFER RS03115
gene id: 338969:RFER_RS03115
uniprot id: Q221C6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

338969:RFER RS20165
gene id: 338969:RFER_RS20165
uniprot id: Q21RC8
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

338969:RFER RS01975
gene id: 338969:RFER_RS01975
uniprot id: Q222A3
names: Cofactor
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

338969:RFER RS20775
gene id: 338969:RFER_RS20775
uniprot id: Q21R05
names: Similarity
messages: Belongs to the HypE family.

338969:RFER RS11665
gene id: 338969:RFER_RS11665
uniprot id: Q21W24
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

338969:RFER RS19780
gene id: 338969:RFER_RS19780
uniprot id: Q21RK9
names: Function
names: Similarity
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

338969:RFER RS02410
gene id: 338969:RFER_RS02410
uniprot id: Q221R7
names: Similarity
messages: Belongs to the glutathione peroxidase family.

338969:RFER RS19390
gene id: 338969:RFER_RS19390
uniprot id: Q21RT7
names: Similarity
messages: Belongs to the GST superfamily. NadH family.

338969:RFER RS21150
gene id: 338969:RFER_RS21150
uniprot id: Q21QT7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

338969:RFER RS18060
gene id: 338969:RFER_RS18060
uniprot id: Q21SI3
names: Similarity
messages: Belongs to the four-carbon acid sugar kinase family.

338969:RFER RS16095
gene id: 338969:RFER_RS16095
uniprot id: Q21TL4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

338969:RFER RS00005
gene id: 338969:RFER_RS00005
uniprot id: Q223G0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

338969:RFER RS00435
gene id: 338969:RFER_RS00435
uniprot id: Q223F6
names: Similarity
messages: Belongs to the peptidase M24B family.

338969:RFER RS20330
gene id: 338969:RFER_RS20330
uniprot id: Q21R95
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

338969:RFER RS20375
gene id: 338969:RFER_RS20375
uniprot id: Q21R86
names: Similarity
messages: Belongs to the methylglyoxal synthase family.

338969:RFER RS00550
gene id: 338969:RFER_RS00550
uniprot id: Q223D3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase delta chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

338969:RFER RS06655
gene id: 338969:RFER_RS06655
uniprot id: Q21YU4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

338969:RFER RS19890
gene id: 338969:RFER_RS19890
uniprot id: Q21RI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Membrane

338969:RFER RS11320
gene id: 338969:RFER_RS11320
uniprot id: Q21W89
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

338969:RFER RS16100
gene id: 338969:RFER_RS16100
uniprot id: Q21TL3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

338969:RFER RS19335
gene id: 338969:RFER_RS19335
uniprot id: Q21RU8
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

338969:RFER RS01745
gene id: 338969:RFER_RS01745
uniprot id: Q222E8
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

338969:RFER RS11095
gene id: 338969:RFER_RS11095
uniprot id: Q21WD4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

338969:RFER RS20200
gene id: 338969:RFER_RS20200
uniprot id: Q21RC1
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

338969:RFER RS02905
gene id: 338969:RFER_RS02905
uniprot id: Q221G7
names: Subcellular Location Annotation
messages: Membrane

338969:RFER RS21075
gene id: 338969:RFER_RS21075
uniprot id: Q21QV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

338969:RFER RS02345
gene id: 338969:RFER_RS02345
uniprot id: Q221T0
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

338969:RFER RS14740
gene id: 338969:RFER_RS14740
uniprot id: Q21UC8
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MsrP family.
messages: Binds 1 Mo-molybdopterin (Mo-MPT) cofactor per subunit.
messages: Heterodimer of a catalytic subunit (MsrP) and a heme-binding subunit (MsrQ).
messages: Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide.
messages: Periplasm
messages: Predicted to be exported by the Tat system. The position of the signal peptide cleavage has not been experimentally proven.

338969:RFER RS13940
gene id: 338969:RFER_RS13940
uniprot id: Q21UT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

338969:RFER RS07000
gene id: 338969:RFER_RS07000
uniprot id: Q21YM8
names: Similarity
messages: Belongs to the phosphoribulokinase family.

338969:RFER RS19095
gene id: 338969:RFER_RS19095
uniprot id: Q21RZ6
names: Similarity
messages: Belongs to the FrmR/RcnR family.

338969:RFER RS14875
gene id: 338969:RFER_RS14875
uniprot id: Q21UA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

338969:RFER RS04055
gene id: 338969:RFER_RS04055
uniprot id: Q220J1
names: Subcellular Location Annotation
messages: Mitochondrion

338969:RFER RS02850
gene id: 338969:RFER_RS02850
uniprot id: Q221H8
names: Similarity
messages: Belongs to the OsmC/Ohr family.

338969:RFER RS18205
gene id: 338969:RFER_RS18205
uniprot id: Q21SF5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

338969:RFER RS06480
gene id: 338969:RFER_RS06480
uniprot id: Q21YX8
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).

338969:RFER RS08330
gene id: 338969:RFER_RS08330
uniprot id: Q21XX7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

338969:RFER RS18115
gene id: 338969:RFER_RS18115
uniprot id: Q21SH2
names: Similarity
messages: Belongs to the DEAD box helicase family.

338969:RFER RS10750
gene id: 338969:RFER_RS10750
uniprot id: Q21WK3
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

338969:RFER RS23120
gene id: 338969:RFER_RS23120
uniprot id: Q21SC4
names: Similarity
messages: Belongs to the hemerythrin family.

338969:RFER RS12830
gene id: 338969:RFER_RS12830
uniprot id: Q21VE7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
messages: Cell inner membrane
messages: Transport of potassium into the cell. Likely operates as a K(+):H(+) symporter.

338969:RFER RS03100
gene id: 338969:RFER_RS03100
uniprot id: Q221C9
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

338969:RFER RS09270
gene id: 338969:RFER_RS09270
uniprot id: Q21XE3
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

338969:RFER RS03870
gene id: 338969:RFER_RS03870
uniprot id: Q220M7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptA family.
messages: Component of the lipopolysaccharide transport and assembly complex.
messages: Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane.
messages: Periplasm

338969:RFER RS00010
gene id: 338969:RFER_RS00010
uniprot id: Q223F9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

338969:RFER RS10060
gene id: 338969:RFER_RS10060
uniprot id: Q21WY8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

338969:RFER RS18570
gene id: 338969:RFER_RS18570
uniprot id: Q21S90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Cell membrane
messages: Membrane

338969:RFER RS10160
gene id: 338969:RFER_RS10160
uniprot id: Q21WW8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
messages: Cytoplasm
messages: Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.

338969:RFER RS10175
gene id: 338969:RFER_RS10175
uniprot id: Q21WW5
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

338969:RFER RS06770
gene id: 338969:RFER_RS06770
uniprot id: Q21YS2
names: Similarity
messages: Belongs to the YkuD family.

338969:RFER RS17245
gene id: 338969:RFER_RS17245
uniprot id: Q21SY7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UreF family.
messages: Cytoplasm
messages: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
messages: UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

338969:RFER RS02990
gene id: 338969:RFER_RS02990
uniprot id: Q221F0
names: Subcellular Location Annotation
messages: Cytoplasm

338969:RFER RS00245
gene id: 338969:RFER_RS00245
uniprot id: Q21QL6
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

338969:RFER RS21305
gene id: 338969:RFER_RS21305
uniprot id: Q21QR1
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

338969:RFER RS14065
gene id: 338969:RFER_RS14065
uniprot id: Q21UR0
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

338969:RFER RS12770
gene id: 338969:RFER_RS12770
uniprot id: Q21VF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

338969:RFER RS11475
gene id: 338969:RFER_RS11475
uniprot id: Q21W59
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

338969:RFER RS07680
gene id: 338969:RFER_RS07680
uniprot id: Q21Y96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 3 family.
messages: Periplasm

338969:RFER RS09920
gene id: 338969:RFER_RS09920
uniprot id: Q21X15
names: Subcellular Location Annotation
messages: Membrane

338969:RFER RS02955
gene id: 338969:RFER_RS02955
uniprot id: Q221F7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

338969:RFER RS20840
gene id: 338969:RFER_RS20840
uniprot id: Q21QZ3
names: Similarity
messages: Belongs to the transketolase family.

338969:RFER RS04150
gene id: 338969:RFER_RS04150
uniprot id: Q220H2
names: Similarity
messages: Belongs to the peptidase S16 family.

338969:RFER RS08125
gene id: 338969:RFER_RS08125
uniprot id: Q21Y16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

338969:RFER RS17935
gene id: 338969:RFER_RS17935
uniprot id: Q21SK8
names: Subcellular Location Annotation
messages: Membrane

338969:RFER RS02540
gene id: 338969:RFER_RS02540
uniprot id: Q221P0
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

338969:RFER RS18210
gene id: 338969:RFER_RS18210
uniprot id: Q21SF4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

338969:RFER RS17045
gene id: 338969:RFER_RS17045
uniprot id: Q21T27
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

338969:RFER RS18515
gene id: 338969:RFER_RS18515
uniprot id: Q21S99
names: Similarity
messages: Belongs to the asparagine synthetase family.

338969:RFER RS20365
gene id: 338969:RFER_RS20365
uniprot id: Q21R88
names: Similarity
messages: Belongs to the GST superfamily.

338969:RFER RS16950
gene id: 338969:RFER_RS16950
uniprot id: Q21T46
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

338969:RFER RS07335
gene id: 338969:RFER_RS07335
uniprot id: Q21YG2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

338969:RFER RS15275
gene id: 338969:RFER_RS15275
uniprot id: Q21U20
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-(-)-3-hydroxybutyrate oligomer hydrolase family.
messages: Participates in the degradation of poly-3-hydroxybutyrate (PHB). It works downstream of poly(3-hydroxybutyrate) depolymerase, hydrolyzing D(-)-3-hydroxybutyrate oligomers of various length (3HB-oligomers) into 3HB-monomers.
messages: Secreted

338969:RFER RS07490
gene id: 338969:RFER_RS07490
uniprot id: Q21YD2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

338969:RFER RS13185
gene id: 338969:RFER_RS13185
uniprot id: Q21V77
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell inner membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.

338969:RFER RS01720
gene id: 338969:RFER_RS01720
uniprot id: Q222F3
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

338969:RFER RS10960
gene id: 338969:RFER_RS10960
uniprot id: Q21WG0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. RhlE subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in ribosome assembly. Has RNA-dependent ATPase activity and unwinds double-stranded RNA.

338969:RFER RS10755
gene id: 338969:RFER_RS10755
uniprot id: Q21WK2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

338969:RFER RS07815
gene id: 338969:RFER_RS07815
uniprot id: Q21Y70
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

338969:RFER RS10330
gene id: 338969:RFER_RS10330
uniprot id: Q21WT4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M20A family. DapE subfamily.
messages: Binds 2 Zn(2+) or Co(2+) ions per subunit.
messages: Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
messages: Homodimer.

338969:RFER RS12070
gene id: 338969:RFER_RS12070
uniprot id: Q21VU6
names: Subcellular Location Annotation
messages: Membrane

338969:RFER RS06755
gene id: 338969:RFER_RS06755
uniprot id: Q21YS5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxH family.
messages: Binds 2 Mn(2+) ions per subunit in a binuclear metal center.
messages: Cell inner membrane
messages: Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

338969:RFER RS18780
gene id: 338969:RFER_RS18780
uniprot id: Q21S58
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

338969:RFER RS05845
gene id: 338969:RFER_RS05845
uniprot id: Q21ZA1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase C chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

338969:RFER RS10470
gene id: 338969:RFER_RS10470
uniprot id: Q21WQ7
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

338969:RFER RS19170
gene id: 338969:RFER_RS19170
uniprot id: Q21RY1
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

338969:RFER RS02350
gene id: 338969:RFER_RS02350
uniprot id: Q221S9
names: Similarity
messages: Belongs to the P(II) protein family.

338969:RFER RS18000
gene id: 338969:RFER_RS18000
uniprot id: Q21SJ5
names: Function
names: Similarity
messages: Belongs to the BCKDHA family.
messages: The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).

338969:RFER RS19695
gene id: 338969:RFER_RS19695
uniprot id: Q21RM6
names: Similarity
messages: Belongs to the GSP E family.

338969:RFER RS01760
gene id: 338969:RFER_RS01760
uniprot id: Q222E5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

338969:RFER RS08000
gene id: 338969:RFER_RS08000
uniprot id: Q21Y39
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

338969:RFER RS04085
gene id: 338969:RFER_RS04085
uniprot id: Q220I5
names: Cofactor
messages: Binds 1 Mg(2+) ion per subunit.

338969:RFER RS11535
gene id: 338969:RFER_RS11535
uniprot id: Q21W50
names: Similarity
messages: Belongs to the peptidase S66 family.

338969:RFER RS02945
gene id: 338969:RFER_RS02945
uniprot id: Q221F9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
messages: Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD).

338969:RFER RS05195
gene id: 338969:RFER_RS05195
uniprot id: Q21ZM2
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.

338969:RFER RS03285
gene id: 338969:RFER_RS03285
uniprot id: Q220Z3
names: Subcellular Location Annotation
messages: Membrane

338969:RFER RS17735
gene id: 338969:RFER_RS17735
uniprot id: Q21SP8
names: Subcellular Location Annotation
messages: Membrane

338969:RFER RS21490
gene id: 338969:RFER_RS21490
uniprot id: Q21QM3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell inner membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

338969:RFER RS18420
gene id: 338969:RFER_RS18420
uniprot id: Q21SB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HupC/HyaC/HydC family.
messages: Membrane

338969:RFER RS15330
gene id: 338969:RFER_RS15330
uniprot id: Q21U09
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

338969:RFER RS18235
gene id: 338969:RFER_RS18235
uniprot id: Q21SF0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

338969:RFER RS19420
gene id: 338969:RFER_RS19420
uniprot id: Q21RT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Periplasm

338969:RFER RS02870
gene id: 338969:RFER_RS02870
uniprot id: Q221H4
names: Function
messages: This protein is a positive regulator for the phosphate regulon. Transcription of this operon is positively regulated by PhoB and PhoR when phosphate is limited.

338969:RFER RS02915
gene id: 338969:RFER_RS02915
uniprot id: Q221G5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial microcompartment
messages: Belongs to the EutC family.
messages: Binds between the large and small subunits.
messages: Catalyzes the deamination of various vicinal amino-alcohols to oxo compounds. Allows this organism to utilize ethanolamine as the sole source of nitrogen and carbon in the presence of external vitamin B12.
messages: The basic unit is a heterodimer which dimerizes to form tetramers. The heterotetramers trimerize; 6 large subunits form a core ring with 6 small subunits projecting outwards.

338969:RFER RS10505
gene id: 338969:RFER_RS10505
uniprot id: Q21WQ0
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

338969:RFER RS19055
gene id: 338969:RFER_RS19055
uniprot id: Q21S04
names: Function
names: Similarity
messages: Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).

338969:RFER RS19155
gene id: 338969:RFER_RS19155
uniprot id: Q21RY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
messages: Cell inner membrane

338969:RFER RS03325
gene id: 338969:RFER_RS03325
uniprot id: Q220Y5
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

338969:RFER RS21385
gene id: 338969:RFER_RS21385
uniprot id: Q21QP6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

338969:RFER RS18025
gene id: 338969:RFER_RS18025
uniprot id: Q21SJ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Homodimer.
messages: Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.

338969:RFER RS01175
gene id: 338969:RFER_RS01175
uniprot id: Q222R2
names: Similarity
messages: Belongs to the ABC transporter superfamily.

338969:RFER RS14460
gene id: 338969:RFER_RS14460
uniprot id: Q21UI4
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

338969:RFER RS21010
gene id: 338969:RFER_RS21010
uniprot id: Q21QW1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

338969:RFER RS04925
gene id: 338969:RFER_RS04925
uniprot id: Q21ZS2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

338969:RFER RS08910
gene id: 338969:RFER_RS08910
uniprot id: Q21XL4
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

338969:RFER RS07055
gene id: 338969:RFER_RS07055
uniprot id: Q21YL7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

338969:RFER RS19305
gene id: 338969:RFER_RS19305
uniprot id: Q21RV4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

338969:RFER RS19870
gene id: 338969:RFER_RS19870
uniprot id: Q21RI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MlaE permease family.
messages: Cell inner membrane
messages: Membrane

338969:RFER RS02485
gene id: 338969:RFER_RS02485
uniprot id: Q221Q1
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

338969:RFER RS16400
gene id: 338969:RFER_RS16400
uniprot id: Q21TF4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

338969:RFER RS01045
gene id: 338969:RFER_RS01045
uniprot id: Q222T8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

338969:RFER RS01540
gene id: 338969:RFER_RS01540
uniprot id: Q222J0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

338969:RFER RS18065
gene id: 338969:RFER_RS18065
uniprot id: Q21SI2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdgT transporter family.
messages: Catalyzes the proton-dependent uptake of 2-keto-3-deoxygluconate (KDG) into the cell.
messages: Cell inner membrane

338969:RFER RS17280
gene id: 338969:RFER_RS17280
uniprot id: Q21SY1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).

338969:RFER RS11865
gene id: 338969:RFER_RS11865
uniprot id: Q21VY5
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

338969:RFER RS14760
gene id: 338969:RFER_RS14760
uniprot id: Q21UC4
names: Similarity
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.
messages: Membrane

338969:RFER RS06215
gene id: 338969:RFER_RS06215
uniprot id: Q21Z32
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.
messages: Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

338969:RFER RS20010
gene id: 338969:RFER_RS20010
uniprot id: Q21RF9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

338969:RFER RS11185
gene id: 338969:RFER_RS11185
uniprot id: Q21WB6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 2 lipoyl cofactors covalently.
messages: Forms a 24-polypeptide structural core with octahedral symmetry.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

338969:RFER RS19265
gene id: 338969:RFER_RS19265
uniprot id: Q21RW2
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

338969:RFER RS08135
gene id: 338969:RFER_RS08135
uniprot id: Q21Y14
names: Similarity
messages: Belongs to the UPF0276 family.

338969:RFER RS16155
gene id: 338969:RFER_RS16155
uniprot id: Q21TK3
names: PTM
messages: Binds 2 heme c groups covalently per subunit.

338969:RFER RS21375
gene id: 338969:RFER_RS21375
uniprot id: Q21QP8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

338969:RFER RS04660
gene id: 338969:RFER_RS04660
uniprot id: Q21ZX1
names: Similarity
messages: Belongs to the RutC family.

338969:RFER RS08600
gene id: 338969:RFER_RS08600
uniprot id: Q21XS4
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

338969:RFER RS02455
gene id: 338969:RFER_RS02455
uniprot id: Q221Q8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIB subfamily.
messages: Cell inner membrane
messages: Mediates magnesium influx to the cytosol.

338969:RFER RS19835
gene id: 338969:RFER_RS19835
uniprot id: Q21RJ8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated exonuclease Cas4 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).
messages: Mg(2+) or Mn(2+) required for ssDNA cleavage activity.

338969:RFER RS17240
gene id: 338969:RFER_RS17240
uniprot id: Q21SY8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UreE family.
messages: Cytoplasm
messages: Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly.

338969:RFER RS04580
gene id: 338969:RFER_RS04580
uniprot id: Q21ZY7
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

338969:RFER RS04080
gene id: 338969:RFER_RS04080
uniprot id: Q220I6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM86 family.
messages: Membrane

338969:RFER RS04010
gene id: 338969:RFER_RS04010
uniprot id: Q220K0
names: Similarity
messages: Belongs to the glutamate synthase family.

338969:RFER RS04600
gene id: 338969:RFER_RS04600
uniprot id: Q21ZY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. DIT1 subfamily.
messages: Membrane

338969:RFER RS19160
gene id: 338969:RFER_RS19160
uniprot id: Q21RY3
names: Subcellular Location Annotation
messages: Membrane

338969:RFER RS13310
gene id: 338969:RFER_RS13310
uniprot id: Q21V52
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit A family.

338969:RFER RS19595
gene id: 338969:RFER_RS19595
uniprot id: Q21RP6
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

338969:RFER RS03355
gene id: 338969:RFER_RS03355
uniprot id: Q220X9
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

338969:RFER RS04215
gene id: 338969:RFER_RS04215
uniprot id: Q220F9
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.

338969:RFER RS03375
gene id: 338969:RFER_RS03375
uniprot id: Q220X5
names: Subcellular Location Annotation
messages: Membrane

338969:RFER RS10085
gene id: 338969:RFER_RS10085
uniprot id: Q21WY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

338969:RFER RS10335
gene id: 338969:RFER_RS10335
uniprot id: Q21WT3
names: Similarity
messages: Belongs to the GSP E family.

338969:RFER RS13675
gene id: 338969:RFER_RS13675
uniprot id: Q21UY4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.

338969:RFER RS13340
gene id: 338969:RFER_RS13340
uniprot id: Q21V46
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.
messages: Cell membrane
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

338969:RFER RS01370
gene id: 338969:RFER_RS01370
uniprot id: Q222M4
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

338969:RFER RS16340
gene id: 338969:RFER_RS16340
uniprot id: Q21TG6
names: Similarity
names: Subunit
messages: Belongs to the aldehyde dehydrogenase family.
messages: Homotetramer.

338969:RFER RS05510
gene id: 338969:RFER_RS05510
uniprot id: Q21ZG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

338969:RFER RS13490
gene id: 338969:RFER_RS13490
uniprot id: Q21V16
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

338969:RFER RS08555
gene id: 338969:RFER_RS08555
uniprot id: Q21XT3
names: Similarity
messages: Belongs to the SCO1/2 family.

338969:RFER RS11145
gene id: 338969:RFER_RS11145
uniprot id: Q21WC4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

338969:RFER RS14625
gene id: 338969:RFER_RS14625
uniprot id: Q21UF1
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.

338969:RFER RS16120
gene id: 338969:RFER_RS16120
uniprot id: Q21TK9
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

338969:RFER RS18845
gene id: 338969:RFER_RS18845
uniprot id: Q21S45
names: Function
names: Similarity
messages: Belongs to the GTP-binding SRP family.
messages: Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum.

338969:RFER RS12250
gene id: 338969:RFER_RS12250
uniprot id: Q21VR0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.
messages: Membrane

338969:RFER RS11015
gene id: 338969:RFER_RS11015
uniprot id: Q21WE9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HscB family.
messages: Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA.
messages: Interacts with HscA and stimulates its ATPase activity.

338969:RFER RS14535
gene id: 338969:RFER_RS14535
uniprot id: Q21UG9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial solute-binding protein 7 family.
messages: Homodimer.
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: Periplasm

338969:RFER RS18260
gene id: 338969:RFER_RS18260
uniprot id: Q21SE8
names: Similarity
messages: Belongs to the TrpC family.

338969:RFER RS19900
gene id: 338969:RFER_RS19900
uniprot id: Q21RI1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

338969:RFER RS02875
gene id: 338969:RFER_RS02875
uniprot id: Q221H3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

338969:RFER RS01485
gene id: 338969:RFER_RS01485
uniprot id: Q222K2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

338969:RFER RS12225
gene id: 338969:RFER_RS12225
uniprot id: Q21VR5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

338969:RFER RS21485
gene id: 338969:RFER_RS21485
uniprot id: Q21QM4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell inner membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

338969:RFER RS16565
gene id: 338969:RFER_RS16565
uniprot id: Q21TC2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.
messages: In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: In the N-terminal section; belongs to the MIP18 family.

338969:RFER RS06955
gene id: 338969:RFER_RS06955
uniprot id: Q21YN7
names: Function
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.

338969:RFER RS19285
gene id: 338969:RFER_RS19285
uniprot id: Q21RV8
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: Methylated by PrmB.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

338969:RFER RS03200
gene id: 338969:RFER_RS03200
uniprot id: Q221B0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCF family. Uup subfamily.
messages: Cytoplasm
messages: Probably plays a role in ribosome assembly or function. May be involved in resolution of branched DNA intermediates that result from template switching in postreplication gaps. Binds DNA and has ATPase activity.

338969:RFER RS04270
gene id: 338969:RFER_RS04270
uniprot id: Q220E7
names: Subcellular Location Annotation
messages: Membrane

338969:RFER RS06895
gene id: 338969:RFER_RS06895
uniprot id: Q21YQ0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

338969:RFER RS09950
gene id: 338969:RFER_RS09950
uniprot id: Q21X09
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

338969:RFER RS20645
gene id: 338969:RFER_RS20645
uniprot id: Q21R30
names: Cofactor
names: PTM
names: Similarity
messages: Belongs to the NapC/NirT/NrfH family.
messages: Binds 4 heme groups per subunit.

338969:RFER RS11565
gene id: 338969:RFER_RS11565
uniprot id: Q21W44
names: Similarity
messages: Belongs to the ribosome association toxin RatA family.

338969:RFER RS21520
gene id: 338969:RFER_RS21520
uniprot id: Q21QL2
names: Similarity
messages: Belongs to the GSP E family.

338969:RFER RS06665
gene id: 338969:RFER_RS06665
uniprot id: Q21YU2
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

338969:RFER RS19955
gene id: 338969:RFER_RS19955
uniprot id: Q21RH0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

338969:RFER RS16105
gene id: 338969:RFER_RS16105
uniprot id: Q21TL2
names: Subcellular Location Annotation
messages: Membrane

338969:RFER RS21410
gene id: 338969:RFER_RS21410
uniprot id: Q21QN9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

338969:RFER RS18820
gene id: 338969:RFER_RS18820
uniprot id: Q21S50
names: Similarity
messages: Belongs to the MotB family.

338969:RFER RS23165
gene id: 338969:RFER_RS23165
uniprot id: Q21QK7
names: Similarity
messages: Belongs to the TrbG/VirB9 family.

338969:RFER RS18840
gene id: 338969:RFER_RS18840
uniprot id: Q21S46
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

338969:RFER RS08610
gene id: 338969:RFER_RS08610
uniprot id: Q21XS2
names: Subcellular Location Annotation
messages: Membrane

338969:RFER RS04650
gene id: 338969:RFER_RS04650
uniprot id: Q21ZX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

338969:RFER RS00390
gene id: 338969:RFER_RS00390
uniprot id: Q223J8
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG).

338969:RFER RS20770
gene id: 338969:RFER_RS20770
uniprot id: Q21R06
names: Similarity
messages: Belongs to the HypD family.

338969:RFER RS17380
gene id: 338969:RFER_RS17380
uniprot id: Q21SW3
names: Function
names: Similarity
messages: Belongs to the transpeptidase family. FtsI subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall at the division septum.

338969:RFER RS06980
gene id: 338969:RFER_RS06980
uniprot id: Q21YN2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
messages: Cytoplasm
messages: Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity.

338969:RFER RS06735
gene id: 338969:RFER_RS06735
uniprot id: Q21YS8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

338969:RFER RS16000
gene id: 338969:RFER_RS16000
uniprot id: Q21TN3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

338969:RFER RS09050
gene id: 338969:RFER_RS09050
uniprot id: Q21XI7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

338969:RFER RS21180
gene id: 338969:RFER_RS21180
uniprot id: Q21QT2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

338969:RFER RS18315
gene id: 338969:RFER_RS18315
uniprot id: Q21SD8
names: Caution
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IcmF family.
messages: Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly.
messages: Homodimer.
messages: Is composed of four functional domains: the N-terminal 5'-deoxyadenosylcobalamin binding region that is homologous to the small subunit of ICM (IcmB), a middle P-loop GTPase domain (MeaI) that likely acts as a chaperone for ICM, a structured linker region involved in dimer formation, and a C-terminal part that is homologous to the large substrate-binding subunit of ICM (IcmA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

338969:RFER RS09990
gene id: 338969:RFER_RS09990
uniprot id: Q21X02
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

338969:RFER RS01200
gene id: 338969:RFER_RS01200
uniprot id: Q222Q7
names: Similarity
messages: Belongs to the ABC transporter superfamily.

338969:RFER RS06450
gene id: 338969:RFER_RS06450
uniprot id: Q21YY4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Part of the binding-protein-dependent transport system for sn-glycerol-3-phosphate; probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (UgpC), two transmembrane proteins (UgpA and UgpE) and a solute-binding protein (UgpB).

338969:RFER RS10510
gene id: 338969:RFER_RS10510
uniprot id: Q21WP9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein L14 (rplN).

338969:RFER RS08875
gene id: 338969:RFER_RS08875
uniprot id: Q21XM1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

338969:RFER RS03025
gene id: 338969:RFER_RS03025
uniprot id: Q221E3
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

338969:RFER RS00215
gene id: 338969:RFER_RS00215
uniprot id: Q223K3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmD/CycX/HelD family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

338969:RFER RS07635
gene id: 338969:RFER_RS07635
uniprot id: Q21YA4
names: Subcellular Location Annotation
messages: Membrane

338969:RFER RS19045
gene id: 338969:RFER_RS19045
uniprot id: Q21S06
names: Similarity
messages: Belongs to the YjdM family.

338969:RFER RS14690
gene id: 338969:RFER_RS14690
uniprot id: Q21UD8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Plays an essential role in type IV pili and type II pseudopili formation by proteolytically removing the leader sequence from substrate proteins and subsequently monomethylating the alpha-amino group of the newly exposed N-terminal phenylalanine.

338969:RFER RS13205
gene id: 338969:RFER_RS13205
uniprot id: Q21V74
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.

338969:RFER RS14725
gene id: 338969:RFER_RS14725
uniprot id: Q21UD1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell inner membrane
messages: Cytoplasm
messages: May bind 1 zinc ion per subunit.
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

338969:RFER RS13525
gene id: 338969:RFER_RS13525
uniprot id: Q21V09
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

338969:RFER RS19885
gene id: 338969:RFER_RS19885
uniprot id: Q21RI4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transpeptidase family. MrdA subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall.
messages: Cell inner membrane

338969:RFER RS08065
gene id: 338969:RFER_RS08065
uniprot id: Q21Y27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

338969:RFER RS00490
gene id: 338969:RFER_RS00490
uniprot id: Q223E5
names: Domain
names: Function
names: Subcellular Location Annotation
messages: Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation.
messages: Periplasm
messages: The PPIase activity resides only in the second parvulin domain. The N-terminal region and the C-terminal tail are necessary and sufficient for the chaperone activity of SurA. The PPIase activity is dispensable for SurA to function as a chaperone. The N-terminal region and the C-terminal tail are also required for porin recognition.

338969:RFER RS07955
gene id: 338969:RFER_RS07955
uniprot id: Q21Y48
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

338969:RFER RS16825
gene id: 338969:RFER_RS16825
uniprot id: Q21T70
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.

338969:RFER RS04140
gene id: 338969:RFER_RS04140
uniprot id: Q220H4
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus
messages: Repair polymerase that plays a key role in base-excision repair. Has 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity that removes the 5' sugar phosphate and also acts as a DNA polymerase that adds one nucleotide to the 3' end of the arising single-nucleotide gap. Conducts 'gap-filling' DNA synthesis in a stepwise distributive fashion rather than in a processive fashion as for other DNA polymerases.

338969:RFER RS10675
gene id: 338969:RFER_RS10675
uniprot id: Q21WL7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

338969:RFER RS16480
gene id: 338969:RFER_RS16480
uniprot id: Q21TD9
names: Subcellular Location Annotation
messages: Membrane

338969:RFER RS19620
gene id: 338969:RFER_RS19620
uniprot id: Q21RP1
names: Similarity
messages: Belongs to the Smg family.

338969:RFER RS17545
gene id: 338969:RFER_RS17545
uniprot id: Q21ST2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Homodimer.

338969:RFER RS09020
gene id: 338969:RFER_RS09020
uniprot id: Q21XJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic sulfate-binding protein family.
messages: Periplasm

338969:RFER RS01570
gene id: 338969:RFER_RS01570
uniprot id: Q222I4
names: Subcellular Location Annotation
messages: Membrane

338969:RFER RS16665
gene id: 338969:RFER_RS16665
uniprot id: Q21TA2
names: Subcellular Location Annotation
messages: Membrane

338969:RFER RS01105
gene id: 338969:RFER_RS01105
uniprot id: Q222S7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

338969:RFER RS09055
gene id: 338969:RFER_RS09055
uniprot id: Q21XI6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

338969:RFER RS06425
gene id: 338969:RFER_RS06425
uniprot id: Q21YY9
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

338969:RFER RS03695
gene id: 338969:RFER_RS03695
uniprot id: Q220R0
names: Subcellular Location Annotation
messages: Membrane

338969:RFER RS13300
gene id: 338969:RFER_RS13300
uniprot id: Q21V54
names: Similarity
messages: Belongs to the spermidine/spermine synthase family.

338969:RFER RS03745
gene id: 338969:RFER_RS03745
uniprot id: Q220Q0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Cytoplasm
messages: Homodimer.

338969:RFER RS17315
gene id: 338969:RFER_RS17315
uniprot id: Q21SX4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

338969:RFER RS05130
gene id: 338969:RFER_RS05130
uniprot id: Q21ZN5
names: Similarity
messages: Belongs to the DapA family.

338969:RFER RS08815
gene id: 338969:RFER_RS08815
uniprot id: Q21XN3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

338969:RFER RS14120
gene id: 338969:RFER_RS14120
uniprot id: Q21UP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
messages: Cell membrane
messages: Membrane

338969:RFER RS07740
gene id: 338969:RFER_RS07740
uniprot id: Q21Y85
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

338969:RFER RS13390
gene id: 338969:RFER_RS13390
uniprot id: Q21V36
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsB family.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

338969:RFER RS21390
gene id: 338969:RFER_RS21390
uniprot id: Q21QP4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

338969:RFER RS13830
gene id: 338969:RFER_RS13830
uniprot id: Q21UV6
names: Cofactor
names: Similarity
messages: Belongs to the UPF0313 family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

338969:RFER RS05155
gene id: 338969:RFER_RS05155
uniprot id: Q21ZN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

338969:RFER RS13050
gene id: 338969:RFER_RS13050
uniprot id: Q21VA4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

338969:RFER RS20910
gene id: 338969:RFER_RS20910
uniprot id: Q21QX8
names: Cofactor
names: Similarity
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Binds 1 copper ion per subunit, denoted as copper B.
messages: Binds 2 heme groups per subunit, denoted as high- and low-spin.

338969:RFER RS09090
gene id: 338969:RFER_RS09090
uniprot id: Q21XH9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

338969:RFER RS06730
gene id: 338969:RFER_RS06730
uniprot id: Q21YS9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

338969:RFER RS17210
gene id: 338969:RFER_RS17210
uniprot id: Q21SZ4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease beta subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

338969:RFER RS02555
gene id: 338969:RFER_RS02555
uniprot id: Q221N7
names: Similarity
messages: Belongs to the disproportionating enzyme family.

338969:RFER RS08380
gene id: 338969:RFER_RS08380
uniprot id: Q21XW7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

338969:RFER RS15135
gene id: 338969:RFER_RS15135
uniprot id: Q21U49
names: Similarity
messages: Belongs to the asparaginase 1 family.

338969:RFER RS20015
gene id: 338969:RFER_RS20015
uniprot id: Q21RF8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 2 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

338969:RFER RS09385
gene id: 338969:RFER_RS09385
uniprot id: Q21XC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

338969:RFER RS00485
gene id: 338969:RFER_RS00485
uniprot id: Q223E6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

338969:RFER RS09005
gene id: 338969:RFER_RS09005
uniprot id: Q21XJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein SsuA/TauA family.
messages: Periplasm

338969:RFER RS04945
gene id: 338969:RFER_RS04945
uniprot id: Q21ZR9
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

338969:RFER RS04255
gene id: 338969:RFER_RS04255
uniprot id: Q220F1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

338969:RFER RS05430
gene id: 338969:RFER_RS05430
uniprot id: Q21ZH8
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

338969:RFER RS17755
gene id: 338969:RFER_RS17755
uniprot id: Q21SP4
names: Similarity
messages: Belongs to the leucine-binding protein family.

338969:RFER RS09600
gene id: 338969:RFER_RS09600
uniprot id: Q21X78
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

338969:RFER RS15435
gene id: 338969:RFER_RS15435
uniprot id: Q21TY9
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

338969:RFER RS08565
gene id: 338969:RFER_RS08565
uniprot id: Q21XT1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoH subfamily.
messages: Cytoplasm
messages: Interacts with the RNA polymerase core enzyme.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.

338969:RFER RS10475
gene id: 338969:RFER_RS10475
uniprot id: Q21WQ6
names: Cofactor
messages: Binds 2 Mg(2+) ions per monomer.

338969:RFER RS09085
gene id: 338969:RFER_RS09085
uniprot id: Q21XI0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

338969:RFER RS13920
gene id: 338969:RFER_RS13920
uniprot id: Q21UT9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

338969:RFER RS12160
gene id: 338969:RFER_RS12160
uniprot id: Q21VS8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HpcH/HpaI aldolase family. Citrate lyase beta subunit subfamily.
messages: Cytoplasm
messages: Oligomer with a subunit composition of (alpha,beta,gamma)6.
messages: Represents a citryl-ACP lyase.

338969:RFER RS14955
gene id: 338969:RFER_RS14955
uniprot id: Q21U84
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

338969:RFER RS01140
gene id: 338969:RFER_RS01140
uniprot id: Q222S0
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

338969:RFER RS15320
gene id: 338969:RFER_RS15320
uniprot id: Q21U11
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate.
messages: Cytoplasm

338969:RFER RS22320
gene id: 338969:RFER_RS22320
uniprot id: Q21Q59
names: Similarity
messages: Belongs to the GSP E family.

338969:RFER RS10070
gene id: 338969:RFER_RS10070
uniprot id: Q21WY6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

338969:RFER RS10685
gene id: 338969:RFER_RS10685
uniprot id: Q21WL5
names: Subcellular Location Annotation
messages: Membrane

338969:RFER RS05840
gene id: 338969:RFER_RS05840
uniprot id: Q21ZA2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase A chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.

338969:RFER RS20895
gene id: 338969:RFER_RS20895
uniprot id: Q21QY1
names: Similarity
messages: Belongs to the SCO1/2 family.

338969:RFER RS18155
gene id: 338969:RFER_RS18155
uniprot id: Q21SG4
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

338969:RFER RS09960
gene id: 338969:RFER_RS09960
uniprot id: Q21X07
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

338969:RFER RS00155
gene id: 338969:RFER_RS00155
uniprot id: Q223G9
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

338969:RFER RS14665
gene id: 338969:RFER_RS14665
uniprot id: Q21UE3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

338969:RFER RS12215
gene id: 338969:RFER_RS12215
uniprot id: Q21VR7
names: Subcellular Location Annotation
messages: Membrane

338969:RFER RS12000
gene id: 338969:RFER_RS12000
uniprot id: Q21VV9
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

338969:RFER RS18375
gene id: 338969:RFER_RS18375
uniprot id: Q21SC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

338969:RFER RS18790
gene id: 338969:RFER_RS18790
uniprot id: Q21S56
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell inner membrane
messages: Membrane

338969:RFER RS08285
gene id: 338969:RFER_RS08285
uniprot id: Q21XY7
names: Similarity
messages: Belongs to the DapA family.

338969:RFER RS00075
gene id: 338969:RFER_RS00075
uniprot id: Q223J0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. DIT1 subfamily.
messages: Membrane

338969:RFER RS05015
gene id: 338969:RFER_RS05015
uniprot id: Q21ZQ6
names: Subcellular Location Annotation
messages: Membrane

338969:RFER RS10695
gene id: 338969:RFER_RS10695
uniprot id: Q21WL3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

338969:RFER RS13125
gene id: 338969:RFER_RS13125
uniprot id: Q21V89
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

338969:RFER RS17730
gene id: 338969:RFER_RS17730
uniprot id: Q21SP9
names: Subcellular Location Annotation
messages: Membrane

338969:RFER RS06040
gene id: 338969:RFER_RS06040
uniprot id: Q21Z66
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

338969:RFER RS19905
gene id: 338969:RFER_RS19905
uniprot id: Q21RI0
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

338969:RFER RS06205
gene id: 338969:RFER_RS06205
uniprot id: Q21Z34
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. Fucose synthase subfamily.
messages: Catalyzes the two-step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.

338969:RFER RS05160
gene id: 338969:RFER_RS05160
uniprot id: Q21ZM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

338969:RFER RS14540
gene id: 338969:RFER_RS14540
uniprot id: Q21UG8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial solute-binding protein 7 family.
messages: Homodimer.
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: Periplasm

338969:RFER RS11165
gene id: 338969:RFER_RS11165
uniprot id: Q21WC0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

338969:RFER RS13010
gene id: 338969:RFER_RS13010
uniprot id: Q21VB1
names: Similarity
messages: Belongs to the pirin family.

338969:RFER RS02270
gene id: 338969:RFER_RS02270
uniprot id: Q221U6
names: Similarity
messages: Belongs to the acetaldehyde dehydrogenase family.

338969:RFER RS06125
gene id: 338969:RFER_RS06125
uniprot id: Q21Z49
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

338969:RFER RS17285
gene id: 338969:RFER_RS17285
uniprot id: Q21SY0
names: Function
names: Similarity
messages: Belongs to the LpxC family.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

338969:RFER RS03865
gene id: 338969:RFER_RS03865
uniprot id: Q220M8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbA subfamily.
messages: Periplasm

338969:RFER RS11130
gene id: 338969:RFER_RS11130
uniprot id: Q21WC7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

338969:RFER RS19635
gene id: 338969:RFER_RS19635
uniprot id: Q21RN8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

338969:RFER RS20405
gene id: 338969:RFER_RS20405
uniprot id: Q21R80
names: Similarity
messages: Belongs to the YciI family.

338969:RFER RS18190
gene id: 338969:RFER_RS18190
uniprot id: Q21SF8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

338969:RFER RS16655
gene id: 338969:RFER_RS16655
uniprot id: Q21TA4
names: Subcellular Location Annotation
messages: Membrane

338969:RFER RS00015
gene id: 338969:RFER_RS00015
uniprot id: Q223F8
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

338969:RFER RS02940
gene id: 338969:RFER_RS02940
uniprot id: Q221G0
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

338969:RFER RS19525
gene id: 338969:RFER_RS19525
uniprot id: Q21RQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DcuA/DcuB transporter (TC 2.A.13.1) family.
messages: Cell inner membrane
messages: Membrane
messages: Responsible for the transport of C4-dicarboxylates.

338969:RFER RS07845
gene id: 338969:RFER_RS07845
uniprot id: Q21Y65
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

338969:RFER RS05135
gene id: 338969:RFER_RS05135
uniprot id: Q21ZN4
names: Similarity
messages: Belongs to the UxaA family.

338969:RFER RS10480
gene id: 338969:RFER_RS10480
uniprot id: Q21WQ5
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

338969:RFER RS04995
gene id: 338969:RFER_RS04995
uniprot id: Q21ZR0
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

338969:RFER RS10140
gene id: 338969:RFER_RS10140
uniprot id: Q21WX2
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

338969:RFER RS15300
gene id: 338969:RFER_RS15300
uniprot id: Q21U15
names: Function
names: Similarity
messages: Belongs to the Ap4A hydrolase family.
messages: Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.

338969:RFER RS18655
gene id: 338969:RFER_RS18655
uniprot id: Q21S73
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family.
messages: Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
messages: Cell inner membrane

338969:RFER RS05060
gene id: 338969:RFER_RS05060
uniprot id: Q21ZP7
names: Subcellular Location Annotation
messages: Membrane

338969:RFER RS19705
gene id: 338969:RFER_RS19705
uniprot id: Q21RM4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

338969:RFER RS03000
gene id: 338969:RFER_RS03000
uniprot id: Q221E8
names: Subcellular Location Annotation
messages: Membrane

338969:RFER RS07545
gene id: 338969:RFER_RS07545
uniprot id: Q21YC2
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

338969:RFER RS00445
gene id: 338969:RFER_RS00445
uniprot id: Q223F4
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.

338969:RFER RS00835
gene id: 338969:RFER_RS00835
uniprot id: Q222X9
names: Similarity
messages: Belongs to the peptidase M20 family.

338969:RFER RS00985
gene id: 338969:RFER_RS00985
uniprot id: Q222V0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.

338969:RFER RS08770
gene id: 338969:RFER_RS08770
uniprot id: Q21XP2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

338969:RFER RS02895
gene id: 338969:RFER_RS02895
uniprot id: Q221G9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PstS family.
messages: Part of the ABC transporter complex PstSACB involved in phosphate import.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

338969:RFER RS07190
gene id: 338969:RFER_RS07190
uniprot id: Q21YJ0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

338969:RFER RS13260
gene id: 338969:RFER_RS13260
uniprot id: Q21V63
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.

338969:RFER RS01320
gene id: 338969:RFER_RS01320
uniprot id: Q222N4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Homohexamer.
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the CobB/CobQ family.
messages: Involved in acetate metabolism.
messages: The N-terminal region seems to be important for proper quaternary structure. The C-terminal region contains the substrate-binding site.

338969:RFER RS01350
gene id: 338969:RFER_RS01350
uniprot id: Q222M8
names: Subcellular Location Annotation
messages: Membrane

338969:RFER RS06565
gene id: 338969:RFER_RS06565
uniprot id: Q21YW1
names: Similarity
messages: Belongs to the peptidase S41A family.

338969:RFER RS08750
gene id: 338969:RFER_RS08750
uniprot id: Q21XP6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

338969:RFER RS19645
gene id: 338969:RFER_RS19645
uniprot id: Q21RN6
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.

338969:RFER RS20960
gene id: 338969:RFER_RS20960
uniprot id: Q21QX1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

338969:RFER RS17190
gene id: 338969:RFER_RS17190
uniprot id: Q21SZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

338969:RFER RS20445
gene id: 338969:RFER_RS20445
uniprot id: Q21R72
names: Similarity
messages: Belongs to the 6-phosphogluconate dehydrogenase family.

338969:RFER RS14900
gene id: 338969:RFER_RS14900
uniprot id: Q21U95
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

338969:RFER RS02745
gene id: 338969:RFER_RS02745
uniprot id: Q221J9
names: Subcellular Location Annotation
messages: Cytoplasm

338969:RFER RS12945
gene id: 338969:RFER_RS12945
uniprot id: Q21VC4
names: Subcellular Location Annotation
messages: Cytoplasm

338969:RFER RS11645
gene id: 338969:RFER_RS11645
uniprot id: Q21W28
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

338969:RFER RS21080
gene id: 338969:RFER_RS21080
uniprot id: Q21QU9
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

338969:RFER RS14990
gene id: 338969:RFER_RS14990
uniprot id: Q21U77
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b family.
messages: Binds 2 heme groups non-covalently.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

338969:RFER RS02935
gene id: 338969:RFER_RS02935
uniprot id: Q221G1
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

338969:RFER RS18650
gene id: 338969:RFER_RS18650
uniprot id: Q21S74
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

338969:RFER RS12850
gene id: 338969:RFER_RS12850
uniprot id: Q21VE3
names: Similarity
messages: Belongs to the AHA1 family.

338969:RFER RS07065
gene id: 338969:RFER_RS07065
uniprot id: Q21YL5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

338969:RFER RS12800
gene id: 338969:RFER_RS12800
uniprot id: Q21VF3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

338969:RFER RS18805
gene id: 338969:RFER_RS18805
uniprot id: Q21S53
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FlhD family.
messages: Cytoplasm
messages: Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways.
messages: Homodimer; disulfide-linked. Forms a heterohexamer composed of two FlhC and four FlhD subunits. Each FlhC binds a FlhD dimer, forming a heterotrimer, and a hexamer assembles by dimerization of two heterotrimers.
messages: The C-terminal region contains a putative helix-turn-helix (HTH) motif, suggesting that this region may bind DNA.

338969:RFER RS12505
gene id: 338969:RFER_RS12505
uniprot id: Q21VL1
names: Similarity
names: Subunit
messages: Belongs to the beta-eliminating lyase family.
messages: Homotetramer.

338969:RFER RS01035
gene id: 338969:RFER_RS01035
uniprot id: Q222U0
names: Similarity
messages: Belongs to the pyruvate kinase family.

338969:RFER RS04020
gene id: 338969:RFER_RS04020
uniprot id: Q220J8
names: Similarity
messages: Belongs to the pirin family.

338969:RFER RS09900
gene id: 338969:RFER_RS09900
uniprot id: Q21X19
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

338969:RFER RS15140
gene id: 338969:RFER_RS15140
uniprot id: Q21U48
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

338969:RFER RS21780
gene id: 338969:RFER_RS21780
uniprot id: Q21QG1
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

338969:RFER RS07660
gene id: 338969:RFER_RS07660
uniprot id: Q21YA0
names: Similarity
messages: Belongs to the ABC transporter superfamily.

338969:RFER RS13925
gene id: 338969:RFER_RS13925
uniprot id: Q21UT8
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

338969:RFER RS07075
gene id: 338969:RFER_RS07075
uniprot id: Q21YL3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

338969:RFER RS16055
gene id: 338969:RFER_RS16055
uniprot id: Q21TM2
names: Subcellular Location Annotation
messages: Membrane

338969:RFER RS09395
gene id: 338969:RFER_RS09395
uniprot id: Q21XB8
names: Similarity
messages: Belongs to the HesB/IscA family.

338969:RFER RS11940
gene id: 338969:RFER_RS11940
uniprot id: Q21VX1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

338969:RFER RS03605
gene id: 338969:RFER_RS03605
uniprot id: Q220S8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HesB/IscA family.
messages: Binds 1 iron-sulfur cluster per subunit.
messages: Homodimer.
messages: Required for insertion of 4Fe-4S clusters.

338969:RFER RS01865
gene id: 338969:RFER_RS01865
uniprot id: Q222C5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

338969:RFER RS10780
gene id: 338969:RFER_RS10780
uniprot id: Q21WJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

338969:RFER RS01030
gene id: 338969:RFER_RS01030
uniprot id: Q222U1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.
messages: One is catalytic and the other provides a structural contribution.

338969:RFER RS00270
gene id: 338969:RFER_RS00270
uniprot id: Q223L5
names: Function
names: Similarity
messages: Belongs to the ParB family.
messages: Involved in chromosome partition. Localize to both poles of the predivisional cell following completion of DNA replication. Binds to the DNA origin of replication.

338969:RFER RS04100
gene id: 338969:RFER_RS04100
uniprot id: Q220I2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.

338969:RFER RS10920
gene id: 338969:RFER_RS10920
uniprot id: Q21WG9
names: Similarity
messages: Belongs to the aminoglycoside phosphotransferase family.
messages: Belongs to the glycosyl hydrolase 13 family. TreS subfamily.

338969:RFER RS15950
gene id: 338969:RFER_RS15950
uniprot id: Q21TP3
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

338969:RFER RS17360
gene id: 338969:RFER_RS17360
uniprot id: Q21SW6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell inner membrane

338969:RFER RS20520
gene id: 338969:RFER_RS20520
uniprot id: Q21R56
names: Function
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
messages: Catalyzes two reactions in de novo purine nucleotide biosynthesis. Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate.

338969:RFER RS11075
gene id: 338969:RFER_RS11075
uniprot id: Q21WD8
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

338969:RFER RS16430
gene id: 338969:RFER_RS16430
uniprot id: Q21TE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

338969:RFER RS18300
gene id: 338969:RFER_RS18300
uniprot id: Q21SE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Cell inner membrane

338969:RFER RS05605
gene id: 338969:RFER_RS05605
uniprot id: Q21ZE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

338969:RFER RS05305
gene id: 338969:RFER_RS05305
uniprot id: Q21ZK3
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

338969:RFER RS11370
gene id: 338969:RFER_RS11370
uniprot id: Q21W81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

338969:RFER RS09400
gene id: 338969:RFER_RS09400
uniprot id: Q21XB7
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

338969:RFER RS02515
gene id: 338969:RFER_RS02515
uniprot id: Q221P5
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

338969:RFER RS00555
gene id: 338969:RFER_RS00555
uniprot id: Q223D2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell inner membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.

338969:RFER RS21245
gene id: 338969:RFER_RS21245
uniprot id: Q21QS1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

338969:RFER RS15335
gene id: 338969:RFER_RS15335
uniprot id: Q21U08
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

338969:RFER RS09130
gene id: 338969:RFER_RS09130
uniprot id: Q21XH1
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 2 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

338969:RFER RS18500
gene id: 338969:RFER_RS18500
uniprot id: Q21SA2
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family. L-methionine gamma-lyase subfamily.

338969:RFER RS09340
gene id: 338969:RFER_RS09340
uniprot id: Q21XC9
names: Function
names: Similarity
messages: Belongs to the CitG/MdcB family.
messages: Involved in the formation of 2-(5''-phosphoribosyl)-3'-dephosphocoenzyme-A, the prosthetic group of the acyl-carrier protein of the malonate decarboxylase.

338969:RFER RS15265
gene id: 338969:RFER_RS15265
uniprot id: Q21U22
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

338969:RFER RS19310
gene id: 338969:RFER_RS19310
uniprot id: Q21RV3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

338969:RFER RS10575
gene id: 338969:RFER_RS10575
uniprot id: Q21WN6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Pal lipoprotein family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

338969:RFER RS14980
gene id: 338969:RFER_RS14980
uniprot id: Q21U79
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell inner membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

338969:RFER RS17445
gene id: 338969:RFER_RS17445
uniprot id: Q21SV0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.

338969:RFER RS15840
gene id: 338969:RFER_RS15840
uniprot id: Q21TR5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. Carbohydrate importer 2 (CUT2) (TC 3.A.1.2) family.
messages: Cell inner membrane
messages: Part of an ABC transporter complex involved in carbohydrate import. Could be involved in ribose, galactose and/or methyl galactoside import. Responsible for energy coupling to the transport system.

338969:RFER RS09735
gene id: 338969:RFER_RS09735
uniprot id: Q21X51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

338969:RFER RS00780
gene id: 338969:RFER_RS00780
uniprot id: Q222Y9
names: Similarity
messages: Belongs to the DinB family.

338969:RFER RS02690
gene id: 338969:RFER_RS02690
uniprot id: Q221L0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial secretin family. GSP D subfamily.
messages: Cell outer membrane

338969:RFER RS03565
gene id: 338969:RFER_RS03565
uniprot id: Q220T6
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

338969:RFER RS04130
gene id: 338969:RFER_RS04130
uniprot id: Q220H6
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

338969:RFER RS05675
gene id: 338969:RFER_RS05675
uniprot id: Q21ZC9
names: Subcellular Location Annotation
messages: Membrane

338969:RFER RS03140
gene id: 338969:RFER_RS03140
uniprot id: Q221C1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

338969:RFER RS16020
gene id: 338969:RFER_RS16020
uniprot id: Q21TM9
names: Subcellular Location Annotation
messages: Membrane

338969:RFER RS04985
gene id: 338969:RFER_RS04985
uniprot id: Q21ZR1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

338969:RFER RS08755
gene id: 338969:RFER_RS08755
uniprot id: Q21XP5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

338969:RFER RS12320
gene id: 338969:RFER_RS12320
uniprot id: Q21VP8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

338969:RFER RS10095
gene id: 338969:RFER_RS10095
uniprot id: Q21WY1
names: Similarity
messages: Belongs to the skp family.

338969:RFER RS07725
gene id: 338969:RFER_RS07725
uniprot id: Q21Y88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

338969:RFER RS13495
gene id: 338969:RFER_RS13495
uniprot id: Q21V15
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbB/TolQ family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

338969:RFER RS17295
gene id: 338969:RFER_RS17295
uniprot id: Q21SX7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RuvC family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.

338969:RFER RS11285
gene id: 338969:RFER_RS11285
uniprot id: Q21W96
names: Similarity
messages: Belongs to the LOG family.

338969:RFER RS00800
gene id: 338969:RFER_RS00800
uniprot id: Q222Y6
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20 family.
messages: Binds 2 Zn(2+) ions per subunit.

338969:RFER RS12425
gene id: 338969:RFER_RS12425
uniprot id: Q21VM7
names: Similarity
messages: Belongs to the PAPS reductase family. CysD subfamily.

338969:RFER RS17710
gene id: 338969:RFER_RS17710
uniprot id: Q21SQ3
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

338969:RFER RS02930
gene id: 338969:RFER_RS02930
uniprot id: Q221G2
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

338969:RFER RS14790
gene id: 338969:RFER_RS14790
uniprot id: Q21UB7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

338969:RFER RS10935
gene id: 338969:RFER_RS10935
uniprot id: Q21WG6
names: Similarity
messages: Belongs to the glycosyltransferase 20 family.

338969:RFER RS12675
gene id: 338969:RFER_RS12675
uniprot id: Q21VH7
names: Function
names: Similarity
messages: Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

338969:RFER RS02235
gene id: 338969:RFER_RS02235
uniprot id: Q221V3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

338969:RFER RS07745
gene id: 338969:RFER_RS07745
uniprot id: Q21Y84
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

338969:RFER RS20760
gene id: 338969:RFER_RS20760
uniprot id: Q21R08
names: Function
names: Similarity
messages: Belongs to the carbamoyltransferase HypF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases. HypF functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide.

338969:RFER RS14215
gene id: 338969:RFER_RS14215
uniprot id: Q21UN0
names: Function
names: Similarity
messages: In the C-terminal section; belongs to the aldehyde dehydrogenase family.
messages: In the N-terminal section; belongs to the proline dehydrogenase family.
messages: Oxidizes proline to glutamate for use as a carbon and nitrogen source.

338969:RFER RS05860
gene id: 338969:RFER_RS05860
uniprot id: Q21Z98
names: Function
names: Similarity
messages: Belongs to the ATPase gamma chain family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

338969:RFER RS08350
gene id: 338969:RFER_RS08350
uniprot id: Q21XX3
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

338969:RFER RS21695
gene id: 338969:RFER_RS21695
uniprot id: Q21QH7
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

338969:RFER RS19575
gene id: 338969:RFER_RS19575
uniprot id: Q21RQ0
names: Similarity
messages: Belongs to the peptidase A31 family.

338969:RFER RS16375
gene id: 338969:RFER_RS16375
uniprot id: Q21TF9
names: Similarity
messages: Belongs to the CbxX/CfxQ family.

338969:RFER RS08880
gene id: 338969:RFER_RS08880
uniprot id: Q21XM0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 3 family. NagZ subfamily.
messages: Cytoplasm
messages: Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides.

338969:RFER RS05670
gene id: 338969:RFER_RS05670
uniprot id: Q21ZD0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

338969:RFER RS22980
gene id: 338969:RFER_RS22980
uniprot id: Q21X80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

338969:RFER RS02505
gene id: 338969:RFER_RS02505
uniprot id: Q221P7
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

338969:RFER RS13265
gene id: 338969:RFER_RS13265
uniprot id: Q21V62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

338969:RFER RS20825
gene id: 338969:RFER_RS20825
uniprot id: Q21QZ6
names: Similarity
messages: Belongs to the Gfa family.

338969:RFER RS16550
gene id: 338969:RFER_RS16550
uniprot id: Q21TC5
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
messages: In the C-terminal section; belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

338969:RFER RS09615
gene id: 338969:RFER_RS09615
uniprot id: Q21X75
names: Subcellular Location Annotation
messages: Membrane

338969:RFER RS08650
gene id: 338969:RFER_RS08650
uniprot id: Q21XR6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
messages: Homodimer.

338969:RFER RS04530
gene id: 338969:RFER_RS04530
uniprot id: Q21ZZ5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

338969:RFER RS11025
gene id: 338969:RFER_RS11025
uniprot id: Q21WE7
names: Similarity
messages: Belongs to the adrenodoxin/putidaredoxin family.

338969:RFER RS03080
gene id: 338969:RFER_RS03080
uniprot id: Q221D3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

338969:RFER RS10730
gene id: 338969:RFER_RS10730
uniprot id: Q21WK7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

338969:RFER RS14000
gene id: 338969:RFER_RS14000
uniprot id: Q21US3
names: Similarity
messages: Belongs to the peptidase C56 family.

338969:RFER RS08440
gene id: 338969:RFER_RS08440
uniprot id: Q21XV6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

338969:RFER RS13425
gene id: 338969:RFER_RS13425
uniprot id: Q21V29
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.

338969:RFER RS04865
gene id: 338969:RFER_RS04865
uniprot id: Q21ZT5
names: Similarity
messages: Belongs to the thioesterase PaaI family.

338969:RFER RS24430
gene id: 338969:RFER_RS24430
uniprot id: Q221H2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.
messages: Cell inner membrane
messages: Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

338969:RFER RS04645
gene id: 338969:RFER_RS04645
uniprot id: Q21ZX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

338969:RFER RS02655
gene id: 338969:RFER_RS02655
uniprot id: Q221L7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP H family.
messages: Cell inner membrane
messages: Membrane

338969:RFER RS12765
gene id: 338969:RFER_RS12765
uniprot id: Q21VG0
names: Similarity
messages: Belongs to the UPF0162 family.

338969:RFER RS01920
gene id: 338969:RFER_RS01920
uniprot id: Q222B4
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

338969:RFER RS07565
gene id: 338969:RFER_RS07565
uniprot id: Q21YB8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

338969:RFER RS06790
gene id: 338969:RFER_RS06790
uniprot id: Q21YR8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

338969:RFER RS15725
gene id: 338969:RFER_RS15725
uniprot id: Q21TT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

338969:RFER RS20130
gene id: 338969:RFER_RS20130
uniprot id: Q21RD5
names: Subcellular Location Annotation
messages: Membrane

338969:RFER RS13780
gene id: 338969:RFER_RS13780
uniprot id: Q21UW5
names: Subcellular Location Annotation
messages: Membrane

338969:RFER RS02840
gene id: 338969:RFER_RS02840
uniprot id: Q221I0
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

338969:RFER RS13210
gene id: 338969:RFER_RS13210
uniprot id: Q21V73
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.

338969:RFER RS10065
gene id: 338969:RFER_RS10065
uniprot id: Q21WY7
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.

338969:RFER RS13690
gene id: 338969:RFER_RS13690
uniprot id: Q21UY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

338969:RFER RS07935
gene id: 338969:RFER_RS07935
uniprot id: Q21Y51
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.

338969:RFER RS10425
gene id: 338969:RFER_RS10425
uniprot id: Q21WR6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

338969:RFER RS03795
gene id: 338969:RFER_RS03795
uniprot id: Q220P2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

338969:RFER RS13950
gene id: 338969:RFER_RS13950
uniprot id: Q21UT3
names: Similarity
messages: Belongs to the bacterial solute-binding protein 1 family.

338969:RFER RS16780
gene id: 338969:RFER_RS16780
uniprot id: Q21T79
names: Similarity
messages: Belongs to the peptidase S16 family.

338969:RFER RS03315
gene id: 338969:RFER_RS03315
uniprot id: Q220Y7
names: Similarity
messages: Belongs to the FemABX family.

338969:RFER RS03015
gene id: 338969:RFER_RS03015
uniprot id: Q221E5
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The autoendoproteolytic cleavage occurs by a canonical serine protease mechanism, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. During this reaction, the Ser that is part of the protease active site of the proenzyme becomes the pyruvoyl prosthetic group, which constitutes an essential element of the active site of the mature decarboxylase.

338969:RFER RS19220
gene id: 338969:RFER_RS19220
uniprot id: Q21RX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

338969:RFER RS07785
gene id: 338969:RFER_RS07785
uniprot id: Q21Y76
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

338969:RFER RS05460
gene id: 338969:RFER_RS05460
uniprot id: Q21ZH2
names: Cofactor
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A single active site specifically recognizes both ATP and CTP and is responsible for their addition.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 1 subfamily.
messages: Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases.
messages: Comprises two domains: an N-terminal domain containing the nucleotidyltransferase activity and a C-terminal HD domain associated with both phosphodiesterase and phosphatase activities.
messages: Magnesium is required for nucleotidyltransferase activity.
messages: Monomer. Can also form homodimers and oligomers.
messages: Nickel for phosphatase activity.

338969:RFER RS12865
gene id: 338969:RFER_RS12865
uniprot id: Q21VE0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

338969:RFER RS03765
gene id: 338969:RFER_RS03765
uniprot id: Q220P6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

338969:RFER RS18880
gene id: 338969:RFER_RS18880
uniprot id: Q21S38
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

338969:RFER RS09700
gene id: 338969:RFER_RS09700
uniprot id: Q21X58
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK.

338969:RFER RS11835
gene id: 338969:RFER_RS11835
uniprot id: Q21VZ0
names: Similarity
messages: Belongs to the peptidase S11 family.

338969:RFER RS02575
gene id: 338969:RFER_RS02575
uniprot id: Q221N3
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) per subunit.

338969:RFER RS13565
gene id: 338969:RFER_RS13565
uniprot id: Q21V05
names: Function
names: Similarity
names: Subunit
messages: Belongs to the trans-sulfuration enzymes family. MetZ subfamily.
messages: Catalyzes the formation of L-homocysteine from O-succinyl-L-homoserine (OSHS) and hydrogen sulfide.
messages: Homotetramer.

338969:RFER RS08765
gene id: 338969:RFER_RS08765
uniprot id: Q21XP3
names: Similarity
messages: Belongs to the fabD family.

338969:RFER RS02325
gene id: 338969:RFER_RS02325
uniprot id: Q221T4
names: Subcellular Location Annotation
messages: Membrane

338969:RFER RS10420
gene id: 338969:RFER_RS10420
uniprot id: Q21WR7
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

338969:RFER RS15845
gene id: 338969:RFER_RS15845
uniprot id: Q21TR4
names: Subcellular Location Annotation
messages: Membrane

338969:RFER RS09670
gene id: 338969:RFER_RS09670
uniprot id: Q21X64
names: Similarity
messages: Belongs to the threonine synthase family.

338969:RFER RS19090
gene id: 338969:RFER_RS19090
uniprot id: Q21RZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm

338969:RFER RS03840
gene id: 338969:RFER_RS03840
uniprot id: Q220N3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

338969:RFER RS13500
gene id: 338969:RFER_RS13500
uniprot id: Q21V14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

338969:RFER RS11620
gene id: 338969:RFER_RS11620
uniprot id: Q21W33
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

338969:RFER RS05640
gene id: 338969:RFER_RS05640
uniprot id: Q21ZD6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transaldolase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

338969:RFER RS01345
gene id: 338969:RFER_RS01345
uniprot id: Q222M9
names: Subcellular Location Annotation
messages: Membrane

338969:RFER RS05485
gene id: 338969:RFER_RS05485
uniprot id: Q21ZG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

338969:RFER RS18915
gene id: 338969:RFER_RS18915
uniprot id: Q21S31
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Flagellum-specific muramidase which hydrolyzes the peptidoglycan layer to assemble the rod structure in the periplasmic space.
messages: In the C-terminal section; belongs to the glycosyl hydrolase 73 family.
messages: In the N-terminal section; belongs to the FlgJ family.
messages: Periplasm

338969:RFER RS02595
gene id: 338969:RFER_RS02595
uniprot id: Q221M8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

338969:RFER RS16355
gene id: 338969:RFER_RS16355
uniprot id: Q21TG3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family.
messages: Cell inner membrane
messages: Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.
messages: The complex is composed of two ATP-binding proteins (LolD) and two transmembrane proteins (LolC and LolE).

338969:RFER RS09715
gene id: 338969:RFER_RS09715
uniprot id: Q21X55
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

338969:RFER RS17985
gene id: 338969:RFER_RS17985
uniprot id: Q21SJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Molecular chaperone. Has ATPase activity.

338969:RFER RS17400
gene id: 338969:RFER_RS17400
uniprot id: Q21SV9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

338969:RFER RS09120
gene id: 338969:RFER_RS09120
uniprot id: Q21XH3
names: Cofactor
names: Subunit
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD. The complex can form homotrimers.
messages: The heme is bound between the two transmembrane subunits.

338969:RFER RS00945
gene id: 338969:RFER_RS00945
uniprot id: Q222V7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acetylates the N-terminal alanine of ribosomal protein S18.
messages: Belongs to the acetyltransferase family. RimI subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

338969:RFER RS07030
gene id: 338969:RFER_RS07030
uniprot id: Q21YM2
names: Similarity
messages: Belongs to the UPF0111 family.

338969:RFER RS17015
gene id: 338969:RFER_RS17015
uniprot id: Q21T33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

338969:RFER RS12930
gene id: 338969:RFER_RS12930
uniprot id: Q21VC7
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.

338969:RFER RS06725
gene id: 338969:RFER_RS06725
uniprot id: Q21YT0
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

338969:RFER RS10490
gene id: 338969:RFER_RS10490
uniprot id: Q21WQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

338969:RFER RS08365
gene id: 338969:RFER_RS08365
uniprot id: Q21XX0
names: Function
names: Similarity
messages: Belongs to the RapZ-like family.
messages: Displays ATPase and GTPase activities.

338969:RFER RS07355
gene id: 338969:RFER_RS07355
uniprot id: Q21YF8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Monomer.
messages: Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.

338969:RFER RS20335
gene id: 338969:RFER_RS20335
uniprot id: Q21R94
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

338969:RFER RS00545
gene id: 338969:RFER_RS00545
uniprot id: Q223D4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

338969:RFER RS19330
gene id: 338969:RFER_RS19330
uniprot id: Q21RU9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HemJ family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Catalyzes the oxidation of protoporphyrinogen IX to protoporphyrin IX.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

338969:RFER RS08550
gene id: 338969:RFER_RS08550
uniprot id: Q21XT4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell inner membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.

338969:RFER RS09945
gene id: 338969:RFER_RS09945
uniprot id: Q21X10
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

338969:RFER RS02055
gene id: 338969:RFER_RS02055
uniprot id: Q221Y7
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

338969:RFER RS04915
gene id: 338969:RFER_RS04915
uniprot id: Q21ZS4
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

338969:RFER RS05610
gene id: 338969:RFER_RS05610
uniprot id: Q21ZE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

338969:RFER RS10620
gene id: 338969:RFER_RS10620
uniprot id: Q21WM7
names: Function
names: Similarity
messages: Belongs to the Fe(2+)-trafficking protein family.
messages: Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.

338969:RFER RS00685
gene id: 338969:RFER_RS00685
uniprot id: Q223A8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase U32 family. UbiV subfamily.
messages: Forms an heterodimer with UbiU.
messages: Required for O(2)-independent ubiquinone (coenzyme Q) biosynthesis. Together with UbiU, is essential for the C6-hydroxylation reaction in the oxygen-independent ubiquinone biosynthesis pathway.

338969:RFER RS00530
gene id: 338969:RFER_RS00530
uniprot id: Q223D7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

338969:RFER RS11085
gene id: 338969:RFER_RS11085
uniprot id: Q21WD6
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

338969:RFER RS11115
gene id: 338969:RFER_RS11115
uniprot id: Q21WD0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

338969:RFER RS19275
gene id: 338969:RFER_RS19275
uniprot id: Q21RW0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

338969:RFER RS03775
gene id: 338969:RFER_RS03775
uniprot id: Q220P4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LptE lipoprotein family.
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptD.
messages: Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane.

338969:RFER RS18265
gene id: 338969:RFER_RS18265
uniprot id: Q21SE7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.

338969:RFER RS07005
gene id: 338969:RFER_RS07005
uniprot id: Q21YM7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.

338969:RFER RS08810
gene id: 338969:RFER_RS08810
uniprot id: Q21XN4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell inner membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

338969:RFER RS12030
gene id: 338969:RFER_RS12030
uniprot id: Q21VV4
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

338969:RFER RS00055
gene id: 338969:RFER_RS00055
uniprot id: Q223J4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpxP/Spy family.
messages: Periplasm

338969:RFER RS19295
gene id: 338969:RFER_RS19295
uniprot id: Q21RV6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

338969:RFER RS12165
gene id: 338969:RFER_RS12165
uniprot id: Q21VS7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CitD family.
messages: Covalent carrier of the coenzyme of citrate lyase.
messages: Cytoplasm
messages: Oligomer with a subunit composition of (alpha,beta,gamma)6.

338969:RFER RS10645
gene id: 338969:RFER_RS10645
uniprot id: Q21WM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

338969:RFER RS18450
gene id: 338969:RFER_RS18450
uniprot id: Q21SB2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

338969:RFER RS00665
gene id: 338969:RFER_RS00665
uniprot id: Q223B2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

338969:RFER RS07330
gene id: 338969:RFER_RS07330
uniprot id: Q21YG3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

338969:RFER RS08435
gene id: 338969:RFER_RS08435
uniprot id: Q21XV7
names: Similarity
messages: Belongs to the universal stress protein A family.

338969:RFER RS14420
gene id: 338969:RFER_RS14420
uniprot id: Q21UJ2
names: Similarity
messages: Belongs to the AOR/FOR family.

338969:RFER RS11925
gene id: 338969:RFER_RS11925
uniprot id: Q21VX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

338969:RFER RS11875
gene id: 338969:RFER_RS11875
uniprot id: Q21VY3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

338969:RFER RS03440
gene id: 338969:RFER_RS03440
uniprot id: Q220W1
names: Subcellular Location Annotation
messages: Membrane

338969:RFER RS11310
gene id: 338969:RFER_RS11310
uniprot id: Q21W91
names: Similarity
messages: Belongs to the ribose-phosphate pyrophosphokinase family.

338969:RFER RS07440
gene id: 338969:RFER_RS07440
uniprot id: Q21YE2
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

338969:RFER RS03260
gene id: 338969:RFER_RS03260
uniprot id: Q220Z8
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

338969:RFER RS08525
gene id: 338969:RFER_RS08525
uniprot id: Q21XT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

338969:RFER RS04875
gene id: 338969:RFER_RS04875
uniprot id: Q21ZT2
names: Similarity
messages: Belongs to the DSD1 family.

338969:RFER RS12435
gene id: 338969:RFER_RS12435
uniprot id: Q21VM5
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

338969:RFER RS16510
gene id: 338969:RFER_RS16510
uniprot id: Q21TD3
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

338969:RFER RS03855
gene id: 338969:RFER_RS03855
uniprot id: Q220N0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

338969:RFER RS11200
gene id: 338969:RFER_RS11200
uniprot id: Q21WB3
names: Similarity
messages: Belongs to the UPF0229 family.

338969:RFER RS18325
gene id: 338969:RFER_RS18325
uniprot id: Q21SD6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

338969:RFER RS19300
gene id: 338969:RFER_RS19300
uniprot id: Q21RV5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

338969:RFER RS03670
gene id: 338969:RFER_RS03670
uniprot id: Q220R5
names: Similarity
messages: Belongs to the PhoH family.

338969:RFER RS09160
gene id: 338969:RFER_RS09160
uniprot id: Q21XG5
names: Similarity
messages: Belongs to the 4-oxalocrotonate tautomerase family.

338969:RFER RS06370
gene id: 338969:RFER_RS06370
uniprot id: Q21Z00
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

338969:RFER RS22925
gene id: 338969:RFER_RS22925
uniprot id: Q21YG9
names: Similarity
messages: Belongs to the hemerythrin family.

338969:RFER RS12040
gene id: 338969:RFER_RS12040
uniprot id: Q21VV2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

338969:RFER RS09300
gene id: 338969:RFER_RS09300
uniprot id: Q21XD7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial solute-binding protein 7 family.
messages: Periplasm
messages: Solute-binding protein that binds malonate (in vitro) (PubMed:25540822). Probably part of a tripartite ATP-independent periplasmic (TRAP) transport system that mediates solute transport into the cytoplasm.
messages: The complex is comprised of an extracytoplasmic solute-binding protein and a heteromeric permease formed by two transmembrane proteins.

338969:RFER RS06120
gene id: 338969:RFER_RS06120
uniprot id: Q21Z50
names: Subcellular Location Annotation
messages: Membrane

338969:RFER RS03630
gene id: 338969:RFER_RS03630
uniprot id: Q220S3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

338969:RFER RS18900
gene id: 338969:RFER_RS18900
uniprot id: Q21S34
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

338969:RFER RS10415
gene id: 338969:RFER_RS10415
uniprot id: Q21WR8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Catalyzes the dehydration of 6-phospho-D-gluconate to 2-dehydro-3-deoxy-6-phospho-D-gluconate.

338969:RFER RS17010
gene id: 338969:RFER_RS17010
uniprot id: Q21T34
names: Similarity
messages: Belongs to the GSP E family.

338969:RFER RS11635
gene id: 338969:RFER_RS11635
uniprot id: Q21W30
names: Similarity
messages: Belongs to the YfgM family.

338969:RFER RS08300
gene id: 338969:RFER_RS08300
uniprot id: Q21XY4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

338969:RFER RS06130
gene id: 338969:RFER_RS06130
uniprot id: Q21Z48
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

338969:RFER RS09890
gene id: 338969:RFER_RS09890
uniprot id: Q21X21
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

338969:RFER RS13585
gene id: 338969:RFER_RS13585
uniprot id: Q21V01
names: Function
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.
messages: Functions in two distinct reactions of the de novo folate biosynthetic pathway. Catalyzes the addition of a glutamate residue to dihydropteroate (7,8-dihydropteroate or H2Pte) to form dihydrofolate (7,8-dihydrofolate monoglutamate or H2Pte-Glu). Also catalyzes successive additions of L-glutamate to tetrahydrofolate or 10-formyltetrahydrofolate or 5,10-methylenetetrahydrofolate, leading to folylpolyglutamate derivatives.

338969:RFER RS02725
gene id: 338969:RFER_RS02725
uniprot id: Q221K3
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

338969:RFER RS14605
gene id: 338969:RFER_RS14605
uniprot id: Q21UF5
names: Similarity
messages: Belongs to the peptidase U62 family.

338969:RFER RS00205
gene id: 338969:RFER_RS00205
uniprot id: Q223K5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
messages: Cell inner membrane
messages: Membrane

338969:RFER RS15220
gene id: 338969:RFER_RS15220
uniprot id: Q21U31
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

338969:RFER RS19255
gene id: 338969:RFER_RS19255
uniprot id: Q21RW4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

338969:RFER RS03645
gene id: 338969:RFER_RS03645
uniprot id: Q220S0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
messages: Homotetramer.

338969:RFER RS06570
gene id: 338969:RFER_RS06570
uniprot id: Q21YW0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Homodimer.

338969:RFER RS10165
gene id: 338969:RFER_RS10165
uniprot id: Q21WW7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

338969:RFER RS13195
gene id: 338969:RFER_RS13195
uniprot id: Q21V76
names: Function
names: Similarity
messages: Belongs to the CobT family.
messages: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).

338969:RFER RS21290
gene id: 338969:RFER_RS21290
uniprot id: Q21QR3
names: Function
names: Similarity
messages: Belongs to the transposase IS30 family.
messages: Required for the transposition of the insertion element.

338969:RFER RS16180
gene id: 338969:RFER_RS16180
uniprot id: Q21TJ8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ApbE family.
messages: Cell inner membrane
messages: Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.
messages: Magnesium. Can also use manganese.

338969:RFER RS00425
gene id: 338969:RFER_RS00425
uniprot id: Q223G1
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

338969:RFER RS02700
gene id: 338969:RFER_RS02700
uniprot id: Q221K8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

338969:RFER RS00860
gene id: 338969:RFER_RS00860
uniprot id: Q222X4
names: Subcellular Location Annotation
messages: Membrane

338969:RFER RS12690
gene id: 338969:RFER_RS12690
uniprot id: Q21VH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

338969:RFER RS09865
gene id: 338969:RFER_RS09865
uniprot id: Q21X26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

338969:RFER RS03540
gene id: 338969:RFER_RS03540
uniprot id: Q220U1
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 2 family.

338969:RFER RS21300
gene id: 338969:RFER_RS21300
uniprot id: Q21QR2
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

338969:RFER RS15175
gene id: 338969:RFER_RS15175
uniprot id: Q21U41
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

338969:RFER RS04970
gene id: 338969:RFER_RS04970
uniprot id: Q21ZR4
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

338969:RFER RS01190
gene id: 338969:RFER_RS01190
uniprot id: Q222Q9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

338969:RFER RS16395
gene id: 338969:RFER_RS16395
uniprot id: Q21TF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Cell membrane
messages: Membrane

338969:RFER RS17110
gene id: 338969:RFER_RS17110
uniprot id: Q21T14
names: Subcellular Location Annotation
messages: Membrane

338969:RFER RS08870
gene id: 338969:RFER_RS08870
uniprot id: Q21XM2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.

338969:RFER RS11710
gene id: 338969:RFER_RS11710
uniprot id: Q21W15
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

338969:RFER RS10630
gene id: 338969:RFER_RS10630
uniprot id: Q21WM5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsbB family.
messages: Cell inner membrane
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein.

338969:RFER RS17385
gene id: 338969:RFER_RS17385
uniprot id: Q21SW2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsL family.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
messages: Membrane
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

338969:RFER RS01365
gene id: 338969:RFER_RS01365
uniprot id: Q222M5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

338969:RFER RS03985
gene id: 338969:RFER_RS03985
uniprot id: Q220K5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

338969:RFER RS16915
gene id: 338969:RFER_RS16915
uniprot id: Q21T52
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

338969:RFER RS04125
gene id: 338969:RFER_RS04125
uniprot id: Q220H7
names: Similarity
messages: Belongs to the CFA/CMAS family.

338969:RFER RS18620
gene id: 338969:RFER_RS18620
uniprot id: Q21S80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

338969:RFER RS10985
gene id: 338969:RFER_RS10985
uniprot id: Q21WF5
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

338969:RFER RS11830
gene id: 338969:RFER_RS11830
uniprot id: Q21VZ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homotetramer.

338969:RFER RS18835
gene id: 338969:RFER_RS18835
uniprot id: Q21S47
names: Similarity
messages: Belongs to the type III secretion exporter family.

338969:RFER RS09575
gene id: 338969:RFER_RS09575
uniprot id: Q21X83
names: Subcellular Location Annotation
messages: Membrane

338969:RFER RS00465
gene id: 338969:RFER_RS00465
uniprot id: Q223F0
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase family.

338969:RFER RS10515
gene id: 338969:RFER_RS10515
uniprot id: Q21WP8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

338969:RFER RS18625
gene id: 338969:RFER_RS18625
uniprot id: Q21S79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

338969:RFER RS18455
gene id: 338969:RFER_RS18455
uniprot id: Q21SB1
names: Function
names: Similarity
messages: Belongs to the transposase IS30 family.
messages: Required for the transposition of the insertion element.

338969:RFER RS16620
gene id: 338969:RFER_RS16620
uniprot id: Q21TB1
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

338969:RFER RS07240
gene id: 338969:RFER_RS07240
uniprot id: Q21YI0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Cell inner membrane
messages: Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate from the periplasm across the membrane.

338969:RFER RS02750
gene id: 338969:RFER_RS02750
uniprot id: Q221J8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliJ family.
messages: Cell membrane
messages: Membrane

338969:RFER RS20625
gene id: 338969:RFER_RS20625
uniprot id: Q21R35
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

338969:RFER RS17250
gene id: 338969:RFER_RS17250
uniprot id: Q21SY6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
messages: Cytoplasm
messages: Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
messages: Homodimer. UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

338969:RFER RS09115
gene id: 338969:RFER_RS09115
uniprot id: Q21XH4
names: Cofactor
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD.
messages: The heme is bound between the two transmembrane subunits.

338969:RFER RS09550
gene id: 338969:RFER_RS09550
uniprot id: Q21X87
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

338969:RFER RS15150
gene id: 338969:RFER_RS15150
uniprot id: Q21U46
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

338969:RFER RS04630
gene id: 338969:RFER_RS04630
uniprot id: Q21ZX7
names: Similarity
messages: Belongs to the DSD1 family.

338969:RFER RS19845
gene id: 338969:RFER_RS19845
uniprot id: Q21RJ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

338969:RFER RS03305
gene id: 338969:RFER_RS03305
uniprot id: Q220Y9
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

338969:RFER RS02395
gene id: 338969:RFER_RS02395
uniprot id: Q221S0
names: Cofactor
names: Function
messages: Binds 2 [4Fe-4S] clusters.
messages: Component of a complex that catalyzes the oxidation of glycolate to glyoxylate.

338969:RFER RS02430
gene id: 338969:RFER_RS02430
uniprot id: Q221R3
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

338969:RFER RS07460
gene id: 338969:RFER_RS07460
uniprot id: Q21QT8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

338969:RFER RS08355
gene id: 338969:RFER_RS08355
uniprot id: Q21XX2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.

338969:RFER RS11590
gene id: 338969:RFER_RS11590
uniprot id: Q21W39
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

338969:RFER RS16735
gene id: 338969:RFER_RS16735
uniprot id: Q21T88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family.
messages: Membrane

338969:RFER RS09915
gene id: 338969:RFER_RS09915
uniprot id: Q21X16
names: Similarity
messages: Belongs to the Gfa family.

338969:RFER RS18645
gene id: 338969:RFER_RS18645
uniprot id: Q21S75
names: Activity Regulation
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.

338969:RFER RS06590
gene id: 338969:RFER_RS06590
uniprot id: Q21YV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

338969:RFER RS14525
gene id: 338969:RFER_RS14525
uniprot id: Q21UH1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

338969:RFER RS17655
gene id: 338969:RFER_RS17655
uniprot id: Q21SR4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

338969:RFER RS14720
gene id: 338969:RFER_RS14720
uniprot id: Q21UD2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

338969:RFER RS18195
gene id: 338969:RFER_RS18195
uniprot id: Q21SF7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

338969:RFER RS19085
gene id: 338969:RFER_RS19085
uniprot id: Q21RZ8
names: Similarity
names: Subunit
messages: Belongs to the Nudix hydrolase family. NudJ subfamily.
messages: Monomer.

338969:RFER RS05800
gene id: 338969:RFER_RS05800
uniprot id: Q21V15
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbB/TolQ family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

338969:RFER RS11580
gene id: 338969:RFER_RS11580
uniprot id: Q21W41
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

338969:RFER RS16325
gene id: 338969:RFER_RS16325
uniprot id: Q21TG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

338969:RFER RS08390
gene id: 338969:RFER_RS08390
uniprot id: Q21XW5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LolB family.
messages: Cell outer membrane
messages: Membrane
messages: Monomer.

338969:RFER RS13170
gene id: 338969:RFER_RS13170
uniprot id: Q21V80
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

338969:RFER RS17335
gene id: 338969:RFER_RS17335
uniprot id: Q21SX0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

338969:RFER RS13135
gene id: 338969:RFER_RS13135
uniprot id: Q21V87
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

338969:RFER RS19460
gene id: 338969:RFER_RS19460
uniprot id: Q21RS3
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

338969:RFER RS03675
gene id: 338969:RFER_RS03675
uniprot id: Q220R4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

338969:RFER RS16815
gene id: 338969:RFER_RS16815
uniprot id: Q21T72
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

338969:RFER RS02995
gene id: 338969:RFER_RS02995
uniprot id: Q221E9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

338969:RFER RS16445
gene id: 338969:RFER_RS16445
uniprot id: Q21TE6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

338969:RFER RS16965
gene id: 338969:RFER_RS16965
uniprot id: Q21T43
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

338969:RFER RS13575
gene id: 338969:RFER_RS13575
uniprot id: Q21V03
names: Subcellular Location Annotation
messages: Membrane

338969:RFER RS07580
gene id: 338969:RFER_RS07580
uniprot id: Q21YB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

338969:RFER RS03145
gene id: 338969:RFER_RS03145
uniprot id: Q221C0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum
messages: Belongs to the FliD family.
messages: Homopentamer.
messages: Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Secreted

338969:RFER RS01705
gene id: 338969:RFER_RS01705
uniprot id: Q222F7
names: Similarity
messages: Belongs to the shaker potassium channel beta subunit family.

338969:RFER RS16090
gene id: 338969:RFER_RS16090
uniprot id: Q21TL5
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

338969:RFER RS13600
gene id: 338969:RFER_RS13600
uniprot id: Q21UZ8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 2 subfamily.
messages: Cytoplasm
messages: Homotetramer.

338969:RFER RS11850
gene id: 338969:RFER_RS11850
uniprot id: Q21VY7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

338969:RFER RS10275
gene id: 338969:RFER_RS10275
uniprot id: Q21WU5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the helicase family. DinG subfamily. Type 1 sub-subfamily.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA-dependent ATPase and 5'-3' DNA helicase.

338969:RFER RS13520
gene id: 338969:RFER_RS13520
uniprot id: Q21V10
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

338969:RFER RS14595
gene id: 338969:RFER_RS14595
uniprot id: Q21UF7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

338969:RFER RS18220
gene id: 338969:RFER_RS18220
uniprot id: Q21SF2
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

338969:RFER RS16005
gene id: 338969:RFER_RS16005
uniprot id: Q21TN2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the high-potential iron-sulfur protein (HiPIP) family.
messages: Homodimer.
messages: Specific class of high-redox-potential 4Fe-4S ferredoxins. Functions in anaerobic electron transport in most purple and in some other photosynthetic bacteria and in at least one genus (Paracoccus) of halophilic, denitrifying bacteria.

338969:RFER RS12095
gene id: 338969:RFER_RS12095
uniprot id: Q21VU1
names: Function
names: Similarity
messages: Belongs to the SELO family.
messages: Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).

338969:RFER RS02735
gene id: 338969:RFER_RS02735
uniprot id: Q221K1
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Membrane

338969:RFER RS19415
gene id: 338969:RFER_RS19415
uniprot id: Q21RT3
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

338969:RFER RS19690
gene id: 338969:RFER_RS19690
uniprot id: Q21RM7
names: Similarity
messages: Belongs to the GSP E family.

338969:RFER RS12420
gene id: 338969:RFER_RS12420
uniprot id: Q21VM8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
messages: Cytoplasm

338969:RFER RS00225
gene id: 338969:RFER_RS00225
uniprot id: Q21QM0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmB/CycW/HelB family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

338969:RFER RS12490
gene id: 338969:RFER_RS12490
uniprot id: Q21VL4
names: Function
names: Similarity
messages: Belongs to the Thz kinase family.
messages: Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).

338969:RFER RS14040
gene id: 338969:RFER_RS14040
uniprot id: Q21UR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

338969:RFER RS16650
gene id: 338969:RFER_RS16650
uniprot id: Q21TA5
names: Subcellular Location Annotation
messages: Membrane

338969:RFER RS09310
gene id: 338969:RFER_RS09310
uniprot id: Q21XD5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

338969:RFER RS19605
gene id: 338969:RFER_RS19605
uniprot id: Q21RP4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

338969:RFER RS02290
gene id: 338969:RFER_RS02290
uniprot id: Q221U2
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

338969:RFER RS06800
gene id: 338969:RFER_RS06800
uniprot id: Q21YR6
names: Similarity
messages: Belongs to the aspartokinase family.

338969:RFER RS21110
gene id: 338969:RFER_RS21110
uniprot id: Q21QU4
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

338969:RFER RS07910
gene id: 338969:RFER_RS07910
uniprot id: Q21Y56
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

338969:RFER RS13305
gene id: 338969:RFER_RS13305
uniprot id: Q21V53
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

338969:RFER RS06585
gene id: 338969:RFER_RS06585
uniprot id: Q21YV7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecB family.
messages: Cytoplasm
messages: Homotetramer, a dimer of dimers. One homotetramer interacts with 1 SecA dimer.
messages: One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.

338969:RFER RS07160
gene id: 338969:RFER_RS07160
uniprot id: Q21YJ6
names: Similarity
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the malic enzymes family.

338969:RFER RS12005
gene id: 338969:RFER_RS12005
uniprot id: Q21VV8
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

338969:RFER RS02060
gene id: 338969:RFER_RS02060
uniprot id: Q221Y6
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

338969:RFER RS19580
gene id: 338969:RFER_RS19580
uniprot id: Q21RP9
names: Similarity
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.

338969:RFER RS19290
gene id: 338969:RFER_RS19290
uniprot id: Q21RV7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

338969:RFER RS03495
gene id: 338969:RFER_RS03495
uniprot id: Q220V0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

338969:RFER RS10615
gene id: 338969:RFER_RS10615
uniprot id: Q21WM8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Catalyzes the last two steps in the biosynthesis of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity).
messages: Cytoplasm
messages: In the C-terminal section; belongs to the DAO family.
messages: In the N-terminal section; belongs to the methyltransferase superfamily. tRNA (mnm(5)s(2)U34)-methyltransferase family.

338969:RFER RS15000
gene id: 338969:RFER_RS15000
uniprot id: Q21U75
names: Similarity
messages: Belongs to the GST superfamily. HSP26 family.

338969:RFER RS08830
gene id: 338969:RFER_RS08830
uniprot id: Q21XN0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell inner membrane
messages: Cytoplasm
messages: Monomer.

338969:RFER RS12180
gene id: 338969:RFER_RS12180
uniprot id: Q21VS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. DIT1 subfamily.
messages: Membrane

338969:RFER RS05445
gene id: 338969:RFER_RS05445
uniprot id: Q21ZH5
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

338969:RFER RS11545
gene id: 338969:RFER_RS11545
uniprot id: Q21W48
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

338969:RFER RS16580
gene id: 338969:RFER_RS16580
uniprot id: Q21TB9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.

338969:RFER RS00100
gene id: 338969:RFER_RS00100
uniprot id: Q223H9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

338969:RFER RS18255
gene id: 338969:RFER_RS18255
uniprot id: Q21SE9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

338969:RFER RS08895
gene id: 338969:RFER_RS08895
uniprot id: Q21XL7
names: Similarity
messages: Belongs to the SUI1 family.

338969:RFER RS08710
gene id: 338969:RFER_RS08710
uniprot id: Q21XQ4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase E/G family. RNase E subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per homotetramer.
messages: Cell inner membrane
messages: Cytoplasm
messages: Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs.
messages: Homotetramer formed by a dimer of dimers.

338969:RFER RS11125
gene id: 338969:RFER_RS11125
uniprot id: Q21WC8
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

338969:RFER RS02220
gene id: 338969:RFER_RS02220
uniprot id: Q221V6
names: Similarity
messages: Belongs to the four-carbon acid sugar kinase family.

338969:RFER RS07140
gene id: 338969:RFER_RS07140
uniprot id: Q21YK0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

338969:RFER RS07795
gene id: 338969:RFER_RS07795
uniprot id: Q21Y74
names: Cofactor
names: Similarity
messages: Belongs to the peptidase S45 family.
messages: Binds 1 Ca(2+) ion per dimer.

338969:RFER RS22030
gene id: 338969:RFER_RS22030
uniprot id: Q21QB5
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

338969:RFER RS01985
gene id: 338969:RFER_RS01985
uniprot id: Q222A1
names: Similarity
messages: Belongs to the MEMO1 family.

338969:RFER RS18215
gene id: 338969:RFER_RS18215
uniprot id: Q21SF3
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

338969:RFER RS05090
gene id: 338969:RFER_RS05090
uniprot id: Q21ZP1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

338969:RFER RS05645
gene id: 338969:RFER_RS05645
uniprot id: Q21ZD5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

338969:RFER RS02200
gene id: 338969:RFER_RS02200
uniprot id: Q221W0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

338969:RFER RS19505
gene id: 338969:RFER_RS19505
uniprot id: Q21RR3
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.

338969:RFER RS16555
gene id: 338969:RFER_RS16555
uniprot id: Q21TC4
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

338969:RFER RS15720
gene id: 338969:RFER_RS15720
uniprot id: Q21TU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

338969:RFER RS14895
gene id: 338969:RFER_RS14895
uniprot id: Q21U96
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

338969:RFER RS03995
gene id: 338969:RFER_RS03995
uniprot id: Q220K3
names: Subcellular Location Annotation
messages: Membrane

338969:RFER RS00175
gene id: 338969:RFER_RS00175
uniprot id: Q223G5
names: Function
names: Similarity
messages: Belongs to the MinE family.
messages: Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.

338969:RFER RS20510
gene id: 338969:RFER_RS20510
uniprot id: Q21R58
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

338969:RFER RS10170
gene id: 338969:RFER_RS10170
uniprot id: Q21WW6
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

338969:RFER RS13570
gene id: 338969:RFER_RS13570
uniprot id: Q21V04
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

338969:RFER RS20805
gene id: 338969:RFER_RS20805
uniprot id: Q21QZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

338969:RFER RS06705
gene id: 338969:RFER_RS06705
uniprot id: Q21YT4
names: Cofactor
messages: Can also use Mn(2+) ion.

338969:RFER RS10195
gene id: 338969:RFER_RS10195
uniprot id: Q21WW1
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

338969:RFER RS20630
gene id: 338969:RFER_RS20630
uniprot id: Q21R34
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

338969:RFER RS03755
gene id: 338969:RFER_RS03755
uniprot id: Q220P8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

338969:RFER RS03660
gene id: 338969:RFER_RS03660
uniprot id: Q220R7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

338969:RFER RS18370
gene id: 338969:RFER_RS18370
uniprot id: Q21SC7
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

338969:RFER RS18895
gene id: 338969:RFER_RS18895
uniprot id: Q21S35
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of five rings (E,L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

338969:RFER RS12260
gene id: 338969:RFER_RS12260
uniprot id: Q21VQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell inner membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

338969:RFER RS17495
gene id: 338969:RFER_RS17495
uniprot id: Q21SU2
names: Subcellular Location Annotation
messages: Membrane

338969:RFER RS07535
gene id: 338969:RFER_RS07535
uniprot id: Q21YC4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

338969:RFER RS08180
gene id: 338969:RFER_RS08180
uniprot id: Q21Y06
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Phosphonates importer (TC 3.A.1.9.1) family.
messages: Cell inner membrane
messages: Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PhnC), two transmembrane proteins (PhnE) and a solute-binding protein (PhnD).

338969:RFER RS15095
gene id: 338969:RFER_RS15095
uniprot id: Q21U57
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

338969:RFER RS02860
gene id: 338969:RFER_RS02860
uniprot id: Q221H6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response.
messages: Belongs to the SrkA/RdoA protein kinase family.
messages: Cytoplasm
messages: Monomer.

338969:RFER RS17420
gene id: 338969:RFER_RS17420
uniprot id: Q21SV5
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

338969:RFER RS19510
gene id: 338969:RFER_RS19510
uniprot id: Q21RR2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

338969:RFER RS02205
gene id: 338969:RFER_RS02205
uniprot id: Q221V9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

338969:RFER RS15740
gene id: 338969:RFER_RS15740
uniprot id: Q21TT6
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.

338969:RFER RS05440
gene id: 338969:RFER_RS05440
uniprot id: Q21ZH6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

338969:RFER RS12110
gene id: 338969:RFER_RS12110
uniprot id: Q21VT8
names: Similarity
messages: Belongs to the BolA/IbaG family.

338969:RFER RS12155
gene id: 338969:RFER_RS12155
uniprot id: Q21VS9
names: Subcellular Location Annotation
messages: Cytoplasm

338969:RFER RS00670
gene id: 338969:RFER_RS00670
uniprot id: Q223B1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UbiD family.
messages: Binds 1 prenylated FMN (prenyl-FMN) per subunit.
messages: Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis.
messages: Cell membrane
messages: Homohexamer.

338969:RFER RS10455
gene id: 338969:RFER_RS10455
uniprot id: Q21WR0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

338969:RFER RS04390
gene id: 338969:RFER_RS04390
uniprot id: Q220C3
names: Similarity
messages: Belongs to the TPP enzyme family.

338969:RFER RS21845
gene id: 338969:RFER_RS21845
uniprot id: Q21QE8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

338969:RFER RS10835
gene id: 338969:RFER_RS10835
uniprot id: Q21WI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaD Na(+)/H(+) (TC 2.A.62) antiporter family.
messages: Membrane

338969:RFER RS09320
gene id: 338969:RFER_RS09320
uniprot id: Q21XD3
names: PTM
names: Subcellular Location Annotation
messages: Covalently binds the prosthetic group of malonate decarboxylase.
messages: Cytoplasm

338969:RFER RS19250
gene id: 338969:RFER_RS19250
uniprot id: Q21RW5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

338969:RFER RS07525
gene id: 338969:RFER_RS07525
uniprot id: Q21YC6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity).

338969:RFER RS11135
gene id: 338969:RFER_RS11135
uniprot id: Q21WC6
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

338969:RFER RS05975
gene id: 338969:RFER_RS05975
uniprot id: Q21Z77
names: Function
names: Similarity
messages: Belongs to the transposase IS30 family.
messages: Required for the transposition of the insertion element.

338969:RFER RS00475
gene id: 338969:RFER_RS00475
uniprot id: Q223E8
names: Similarity
messages: Belongs to the ribonuclease N1/T1 family.

338969:RFER RS13530
gene id: 338969:RFER_RS13530
uniprot id: Q21V08
names: Similarity
messages: Belongs to the polysaccharide synthase family.

338969:RFER RS16690
gene id: 338969:RFER_RS16690
uniprot id: Q21T97
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenine deaminase type 2 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism.

338969:RFER RS18855
gene id: 338969:RFER_RS18855
uniprot id: Q21S43
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sigma-70 factor family. FliA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes.

338969:RFER RS16995
gene id: 338969:RFER_RS16995
uniprot id: Q21T37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lipase chaperone family.
messages: Cell inner membrane

338969:RFER RS05735
gene id: 338969:RFER_RS05735
uniprot id: Q21ZC0
names: Similarity
messages: Belongs to the phosphohexose mutase family.

338969:RFER RS13110
gene id: 338969:RFER_RS13110
uniprot id: Q21V92
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.

338969:RFER RS00470
gene id: 338969:RFER_RS00470
uniprot id: Q223E9
names: Similarity
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the malic enzymes family.

338969:RFER RS12065
gene id: 338969:RFER_RS12065
uniprot id: Q21VU7
names: Subcellular Location Annotation
messages: Membrane

338969:RFER RS09040
gene id: 338969:RFER_RS09040
uniprot id: Q21XI9
names: Similarity
messages: Belongs to the YggT family.

338969:RFER RS14880
gene id: 338969:RFER_RS14880
uniprot id: Q21U99
names: Similarity
messages: Belongs to the BolA/IbaG family.

338969:RFER RS19545
gene id: 338969:RFER_RS19545
uniprot id: Q21RQ6
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

338969:RFER RS19675
gene id: 338969:RFER_RS19675
uniprot id: Q21RN0
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIS family. GmhA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
messages: Cytoplasm
messages: Homotetramer.
messages: The reaction produces a racemic mixture of D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate.

338969:RFER RS14930
gene id: 338969:RFER_RS14930
uniprot id: Q21U89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA-PH family.
messages: Cytoplasm

338969:RFER RS11450
gene id: 338969:RFER_RS11450
uniprot id: Q21W64
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetyl-CoA hydrolase/transferase family.
messages: Coenzyme A-transferase that converts butyrate to butyryl-CoA.
messages: Cytoplasm

338969:RFER RS20595
gene id: 338969:RFER_RS20595
uniprot id: Q21R41
names: Subcellular Location Annotation
messages: Membrane

338969:RFER RS03620
gene id: 338969:RFER_RS03620
uniprot id: Q220S5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

338969:RFER RS04380
gene id: 338969:RFER_RS04380
uniprot id: Q220C5
names: Similarity
names: Subunit
messages: Belongs to the aldehyde dehydrogenase family.
messages: Homotetramer.

338969:RFER RS14745
gene id: 338969:RFER_RS14745
uniprot id: Q21UC7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MsrQ family.
messages: Binds 1 FMN per subunit.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Cell inner membrane
messages: Heterodimer of a catalytic subunit (MsrP) and a heme-binding subunit (MsrQ).
messages: Membrane
messages: Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain.

338969:RFER RS14680
gene id: 338969:RFER_RS14680
uniprot id: Q21UE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP E family.
messages: Cytoplasm

338969:RFER RS02400
gene id: 338969:RFER_RS02400
uniprot id: Q221R9
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

338969:RFER RS19270
gene id: 338969:RFER_RS19270
uniprot id: Q21RW1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

338969:RFER RS18990
gene id: 338969:RFER_RS18990
uniprot id: Q21S17
names: Similarity
messages: Belongs to the bacterial phospholipase C family.

338969:RFER RS04920
gene id: 338969:RFER_RS04920
uniprot id: Q21ZS3
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

338969:RFER RS08410
gene id: 338969:RFER_RS08410
uniprot id: Q21XW2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

338969:RFER RS05205
gene id: 338969:RFER_RS05205
uniprot id: Q21ZM0
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

338969:RFER RS18460
gene id: 338969:RFER_RS18460
uniprot id: Q21SB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

338969:RFER RS14585
gene id: 338969:RFER_RS14585
uniprot id: Q21UF9
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

338969:RFER RS02660
gene id: 338969:RFER_RS02660
uniprot id: Q221L6
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GSP I family.
messages: Cell inner membrane
messages: Cleaved by prepilin peptidase.
messages: Component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.
messages: Membrane
messages: Type II secretion is composed of four main components: the outer membrane complex, the inner membrane complex, the cytoplasmic secretion ATPase and the periplasm-spanning pseudopilus.

338969:RFER RS00210
gene id: 338969:RFER_RS00210
uniprot id: Q223K4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmE/CycJ family.
messages: Cell inner membrane
messages: Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.

338969:RFER RS13955
gene id: 338969:RFER_RS13955
uniprot id: Q21UT2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK.

338969:RFER RS12695
gene id: 338969:RFER_RS12695
uniprot id: Q21VH3
names: Subcellular Location Annotation
messages: Membrane

338969:RFER RS10765
gene id: 338969:RFER_RS10765
uniprot id: Q21WK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

338969:RFER RS15285
gene id: 338969:RFER_RS15285
uniprot id: Q21U18
names: Caution
names: Function
names: Similarity
messages: Belongs to the Dus family. DusC subfamily.
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U16 in tRNAs.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

338969:RFER RS08970
gene id: 338969:RFER_RS08970
uniprot id: Q21XK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

338969:RFER RS20730
gene id: 338969:RFER_RS20730
uniprot id: Q21R14
names: Similarity
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.

338969:RFER RS18185
gene id: 338969:RFER_RS18185
uniprot id: Q21SF9
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

338969:RFER RS07520
gene id: 338969:RFER_RS07520
uniprot id: Q21YC7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

338969:RFER RS11965
gene id: 338969:RFER_RS11965
uniprot id: Q21VW6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family. QueF type 2 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm
messages: Homodimer.

338969:RFER RS04335
gene id: 338969:RFER_RS04335
uniprot id: Q220D4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase C15 family.
messages: Cytoplasm
messages: Homotetramer.
messages: Removes 5-oxoproline from various penultimate amino acid residues except L-proline.

338969:RFER RS21145
gene id: 338969:RFER_RS21145
uniprot id: Q21QT8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

338969:RFER RS03835
gene id: 338969:RFER_RS03835
uniprot id: Q220N4
names: Subcellular Location Annotation
messages: Membrane

338969:RFER RS04910
gene id: 338969:RFER_RS04910
uniprot id: Q21ZS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

338969:RFER RS11570
gene id: 338969:RFER_RS11570
uniprot id: Q21W43
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

338969:RFER RS15165
gene id: 338969:RFER_RS15165
uniprot id: Q21U43
names: Similarity
messages: Belongs to the phosphohexose mutase family.

338969:RFER RS19375
gene id: 338969:RFER_RS19375
uniprot id: Q21RU0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

338969:RFER RS14920
gene id: 338969:RFER_RS14920
uniprot id: Q21U91
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

338969:RFER RS09870
gene id: 338969:RFER_RS09870
uniprot id: Q21X25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

338969:RFER RS07105
gene id: 338969:RFER_RS07105
uniprot id: Q21YK7
names: Similarity
messages: Belongs to the DEAD box helicase family.

338969:RFER RS19495
gene id: 338969:RFER_RS19495
uniprot id: Q21RR5
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

338969:RFER RS07365
gene id: 338969:RFER_RS07365
uniprot id: Q21YF6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

338969:RFER RS07380
gene id: 338969:RFER_RS07380
uniprot id: Q21YF3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: Monomer.
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

338969:RFER RS03020
gene id: 338969:RFER_RS03020
uniprot id: Q221E4
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

338969:RFER RS14115
gene id: 338969:RFER_RS14115
uniprot id: Q21UQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Membrane

338969:RFER RS11480
gene id: 338969:RFER_RS11480
uniprot id: Q21W58
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

338969:RFER RS10395
gene id: 338969:RFER_RS10395
uniprot id: Q21WS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

338969:RFER RS04825
gene id: 338969:RFER_RS04825
uniprot id: Q21ZU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

338969:RFER RS15995
gene id: 338969:RFER_RS15995
uniprot id: Q21TN4
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

338969:RFER RS11020
gene id: 338969:RFER_RS11020
uniprot id: Q21WE8
names: Function
names: Similarity
messages: Belongs to the heat shock protein 70 family.
messages: Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB.

338969:RFER RS16420
gene id: 338969:RFER_RS16420
uniprot id: Q21TF1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.

338969:RFER RS04330
gene id: 338969:RFER_RS04330
uniprot id: Q220D5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LamB/PxpA family.
messages: Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
messages: Forms a complex composed of PxpA, PxpB and PxpC.

338969:RFER RS05635
gene id: 338969:RFER_RS05635
uniprot id: Q21ZD7
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

338969:RFER RS19700
gene id: 338969:RFER_RS19700
uniprot id: Q21RM5
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

338969:RFER RS04260
gene id: 338969:RFER_RS04260
uniprot id: Q220E9
names: Subcellular Location Annotation
messages: Membrane

338969:RFER RS09290
gene id: 338969:RFER_RS09290
uniprot id: Q21XD9
names: Similarity
messages: Belongs to the leucine-binding protein family.

338969:RFER RS07375
gene id: 338969:RFER_RS07375
uniprot id: Q21YF4
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

338969:RFER RS01795
gene id: 338969:RFER_RS01795
uniprot id: Q222D8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

338969:RFER RS17780
gene id: 338969:RFER_RS17780
uniprot id: Q21SN9
names: Similarity
messages: Belongs to the TPP enzyme family.

338969:RFER RS00570
gene id: 338969:RFER_RS00570
uniprot id: Q223C9
names: Subcellular Location Annotation
messages: Membrane

338969:RFER RS04735
gene id: 338969:RFER_RS04735
uniprot id: Q21ZV8
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

338969:RFER RS19810
gene id: 338969:RFER_RS19810
uniprot id: Q21RK3
names: Similarity
messages: In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.
messages: In the central section; belongs to the CRISPR-associated helicase Cas3 family.

338969:RFER RS02465
gene id: 338969:RFER_RS02465
uniprot id: Q221Q5
names: Subcellular Location Annotation
messages: Membrane

338969:RFER RS06405
gene id: 338969:RFER_RS06405
uniprot id: Q21YZ3
names: Similarity
messages: Belongs to the glutaredoxin family. Monothiol subfamily.

338969:RFER RS05010
gene id: 338969:RFER_RS05010
uniprot id: Q21ZQ7
names: Subcellular Location Annotation
messages: Membrane

338969:RFER RS16195
gene id: 338969:RFER_RS16195
uniprot id: Q21TJ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NosZ family.
messages: Homodimer.
messages: In the C-terminal section; belongs to the cytochrome c oxidase subunit 2 family.
messages: Nitrous-oxide reductase is part of a bacterial respiratory system which is activated under anaerobic conditions in the presence of nitrate or nitrous oxide.
messages: Periplasm

338969:RFER RS15105
gene id: 338969:RFER_RS15105
uniprot id: Q21U55
names: Similarity
messages: Belongs to the CcdB toxin family.

338969:RFER RS13120
gene id: 338969:RFER_RS13120
uniprot id: Q21V90
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

338969:RFER RS18885
gene id: 338969:RFER_RS18885
uniprot id: Q21S37
names: Function
names: Similarity
messages: Belongs to the FlgD family.
messages: Required for flagellar hook formation. May act as a scaffolding protein.

338969:RFER RS12230
gene id: 338969:RFER_RS12230
uniprot id: Q21VR4
names: Activity Regulation
names: Caution
names: Domain
names: Function
names: Similarity
messages: Belongs to the GlnD family.
messages: Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism.
messages: Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity.

338969:RFER RS14975
gene id: 338969:RFER_RS14975
uniprot id: Q21U80
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PdxA family.
messages: Binds 1 divalent metal cation per subunit. Can use ions such as Zn(2+), Mg(2+) or Co(2+).
messages: Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).
messages: Cytoplasm
messages: Homodimer.
messages: The active site is located at the dimer interface.

338969:RFER RS17855
gene id: 338969:RFER_RS17855
uniprot id: Q21SM4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

338969:RFER RS07340
gene id: 338969:RFER_RS07340
uniprot id: Q21YG1
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

338969:RFER RS18925
gene id: 338969:RFER_RS18925
uniprot id: Q21S29
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Secreted

338969:RFER RS07570
gene id: 338969:RFER_RS07570
uniprot id: Q21YB7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

338969:RFER RS08055
gene id: 338969:RFER_RS08055
uniprot id: Q21Y28
names: Subcellular Location Annotation
messages: Membrane

338969:RFER RS10605
gene id: 338969:RFER_RS10605
uniprot id: Q21WN0
names: Subcellular Location Annotation
messages: Membrane

338969:RFER RS11270
gene id: 338969:RFER_RS11270
uniprot id: Q21W99
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. RlmB subfamily.
messages: Cytoplasm
messages: Specifically methylates the ribose of guanosine 2251 in 23S rRNA.

338969:RFER RS11160
gene id: 338969:RFER_RS11160
uniprot id: Q21WC1
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

338969:RFER RS13430
gene id: 338969:RFER_RS13430
uniprot id: Q21V28
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

338969:RFER RS08745
gene id: 338969:RFER_RS08745
uniprot id: Q21XP7
names: Function
names: Similarity
messages: Belongs to the DUF177 domain family.
messages: Plays a role in synthesis, processing and/or stability of 23S rRNA.

338969:RFER RS06930
gene id: 338969:RFER_RS06930
uniprot id: Q21YP2
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

338969:RFER RS19910
gene id: 338969:RFER_RS19910
uniprot id: Q21RH9
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

338969:RFER RS03125
gene id: 338969:RFER_RS03125
uniprot id: Q221C4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

338969:RFER RS02000
gene id: 338969:RFER_RS02000
uniprot id: Q221Z8
names: Similarity
messages: Belongs to the universal stress protein A family.

338969:RFER RS10610
gene id: 338969:RFER_RS10610
uniprot id: Q21WM9
names: Similarity
messages: Belongs to the peptidase C40 family.

338969:RFER RS21105
gene id: 338969:RFER_RS21105
uniprot id: Q21QU5
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

338969:RFER RS08020
gene id: 338969:RFER_RS08020
uniprot id: Q21Y35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

338969:RFER RS16570
gene id: 338969:RFER_RS16570
uniprot id: Q21TC1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

338969:RFER RS02260
gene id: 338969:RFER_RS02260
uniprot id: Q221U8
names: Similarity
messages: Belongs to the DapA family.

338969:RFER RS05180
gene id: 338969:RFER_RS05180
uniprot id: Q21ZM5
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit A family.

338969:RFER RS18575
gene id: 338969:RFER_RS18575
uniprot id: Q21S89
names: Function
names: Similarity
messages: Anion-transporting ATPase.
messages: Belongs to the arsA ATPase family.

338969:RFER RS09285
gene id: 338969:RFER_RS09285
uniprot id: Q21XE0
names: Subcellular Location Annotation
messages: Membrane

338969:RFER RS00865
gene id: 338969:RFER_RS00865
uniprot id: Q222X3
names: Subcellular Location Annotation
messages: Membrane

338969:RFER RS22755
gene id: 338969:RFER_RS22755
uniprot id: Q21PX9
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family. N(4) subfamily.

338969:RFER RS18505
gene id: 338969:RFER_RS18505
uniprot id: Q21SA1
names: Function
names: Subunit
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
messages: Homodimer. Part of the PDH complex, consisting of multiple copies of pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

338969:RFER RS20400
gene id: 338969:RFER_RS20400
uniprot id: Q21R81
names: Similarity
messages: Belongs to the YciI family.

338969:RFER RS11715
gene id: 338969:RFER_RS11715
uniprot id: Q21W14
names: Function
names: Similarity
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.
messages: E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

338969:RFER RS14970
gene id: 338969:RFER_RS14970
uniprot id: Q21U81
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

338969:RFER RS14845
gene id: 338969:RFER_RS14845
uniprot id: Q21UA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MlaE permease family.
messages: Cell inner membrane
messages: Membrane

338969:RFER RS11005
gene id: 338969:RFER_RS11005
uniprot id: Q21WF1
names: Function
names: Similarity
messages: A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.
messages: Belongs to the NifU family.

338969:RFER RS12145
gene id: 338969:RFER_RS12145
uniprot id: Q21VT1
names: Similarity
messages: Belongs to the CitG/MdcB family.

338969:RFER RS07930
gene id: 338969:RFER_RS07930
uniprot id: Q21Y52
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.
messages: Cytoplasm

338969:RFER RS03770
gene id: 338969:RFER_RS03770
uniprot id: Q220P5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

338969:RFER RS20880
gene id: 338969:RFER_RS20880
uniprot id: Q21QY4
names: Similarity
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.

338969:RFER RS10800
gene id: 338969:RFER_RS10800
uniprot id: Q21WJ3
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

338969:RFER RS12365
gene id: 338969:RFER_RS12365
uniprot id: Q21VN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

338969:RFER RS15295
gene id: 338969:RFER_RS15295
uniprot id: Q21U16
names: Subcellular Location Annotation
messages: Membrane

338969:RFER RS14470
gene id: 338969:RFER_RS14470
uniprot id: Q21UI2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Molybdate importer (TC 3.A.1.8) family.
messages: Cell inner membrane
messages: Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (ModC), two transmembrane proteins (ModB) and a solute-binding protein (ModA).

338969:RFER RS21425
gene id: 338969:RFER_RS21425
uniprot id: Q21QN6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

338969:RFER RS13380
gene id: 338969:RFER_RS13380
uniprot id: Q21V38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

338969:RFER RS07405
gene id: 338969:RFER_RS07405
uniprot id: Q21YE8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-insensitive subfamily.
messages: Cell inner membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force.

338969:RFER RS13485
gene id: 338969:RFER_RS13485
uniprot id: Q21V17
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

338969:RFER RS09415
gene id: 338969:RFER_RS09415
uniprot id: Q21XB4
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.

338969:RFER RS15350
gene id: 338969:RFER_RS15350
uniprot id: Q21U05
names: Function
names: Similarity
messages: Belongs to the IMPDH/GMPR family. GuaC type 2 subfamily.
messages: Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.

338969:RFER RS10030
gene id: 338969:RFER_RS10030
uniprot id: Q21WZ4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

338969:RFER RS19630
gene id: 338969:RFER_RS19630
uniprot id: Q21RN9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

338969:RFER RS19650
gene id: 338969:RFER_RS19650
uniprot id: Q21RN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0073 (Hly-III) family.
messages: Membrane

338969:RFER RS16245
gene id: 338969:RFER_RS16245
uniprot id: Q21TI5
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.

338969:RFER RS19260
gene id: 338969:RFER_RS19260
uniprot id: Q21RW3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity).

338969:RFER RS12210
gene id: 338969:RFER_RS12210
uniprot id: Q21VR8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

338969:RFER RS20635
gene id: 338969:RFER_RS20635
uniprot id: Q21R33
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HemG family.
messages: Binds 1 FMN non-covalently per subunit.
messages: Catalyzes the 6-electron oxidation of protoporphyrinogen IX to form protoporphyrin IX; under anaerobic conditions uses menaquinone as an electron acceptor, under aerobic conditions uses ubiquinone as an electron acceptor.
messages: Cell inner membrane

338969:RFER RS15045
gene id: 338969:RFER_RS15045
uniprot id: Q21U67
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

338969:RFER RS15560
gene id: 338969:RFER_RS15560
uniprot id: Q21TW8
names: Function
names: Similarity
messages: Belongs to the vsr family.
messages: May nick specific sequences that contain T:G mispairs resulting from m5C-deamination.

338969:RFER RS04965
gene id: 338969:RFER_RS04965
uniprot id: Q21ZR5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

338969:RFER RS18870
gene id: 338969:RFER_RS18870
uniprot id: Q21S40
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FlgA family.
messages: Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly.
messages: Periplasm

338969:RFER RS10900
gene id: 338969:RFER_RS10900
uniprot id: Q21WH3
names: Similarity
messages: Belongs to the disproportionating enzyme family.

338969:RFER RS21125
gene id: 338969:RFER_RS21125
uniprot id: Q21QT2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

338969:RFER RS15195
gene id: 338969:RFER_RS15195
uniprot id: Q21U36
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

338969:RFER RS13405
gene id: 338969:RFER_RS13405
uniprot id: Q21V33
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

338969:RFER RS00560
gene id: 338969:RFER_RS00560
uniprot id: Q223D1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase C chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

338969:RFER RS13290
gene id: 338969:RFER_RS13290
uniprot id: Q21V56
names: Similarity
messages: Belongs to the GST superfamily.

338969:RFER RS02580
gene id: 338969:RFER_RS02580
uniprot id: Q221N2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Membrane

338969:RFER RS06375
gene id: 338969:RFER_RS06375
uniprot id: Q21YZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

338969:RFER RS19565
gene id: 338969:RFER_RS19565
uniprot id: Q21RQ2
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.
messages: Monomer.

338969:RFER RS08460
gene id: 338969:RFER_RS08460
uniprot id: Q21XV2
names: Similarity
messages: Belongs to the peptidase M16 family.

338969:RFER RS14685
gene id: 338969:RFER_RS14685
uniprot id: Q21UD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

338969:RFER RS09680
gene id: 338969:RFER_RS09680
uniprot id: Q21X62
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

338969:RFER RS17220
gene id: 338969:RFER_RS17220
uniprot id: Q21SZ2
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
messages: Binds 2 nickel ions per subunit.
messages: Carboxylation allows a single lysine to coordinate two nickel ions.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

338969:RFER RS07720
gene id: 338969:RFER_RS07720
uniprot id: Q21Y89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

338969:RFER RS10990
gene id: 338969:RFER_RS10990
uniprot id: Q21WF4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

338969:RFER RS11390
gene id: 338969:RFER_RS11390
uniprot id: Q21W76
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

338969:RFER RS01525
gene id: 338969:RFER_RS01525
uniprot id: Q222J3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

338969:RFER RS01495
gene id: 338969:RFER_RS01495
uniprot id: Q222K0
names: Similarity
messages: Belongs to the cytochrome P450 family.

338969:RFER RS06645
gene id: 338969:RFER_RS06645
uniprot id: Q21YU6
names: Similarity
messages: Belongs to the pseudomonas-type ThrB family.

338969:RFER RS11975
gene id: 338969:RFER_RS11975
uniprot id: Q21VW4
names: Similarity
messages: Belongs to the UPF0246 family.

338969:RFER RS11685
gene id: 338969:RFER_RS11685
uniprot id: Q21W20
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamD family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

338969:RFER RS07350
gene id: 338969:RFER_RS07350
uniprot id: Q21YF9
names: Similarity
messages: Belongs to the transglycosylase Slt family.

338969:RFER RS14750
gene id: 338969:RFER_RS14750
uniprot id: Q21UC6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

338969:RFER RS12325
gene id: 338969:RFER_RS12325
uniprot id: Q21VP7
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

338969:RFER RS12440
gene id: 338969:RFER_RS12440
uniprot id: Q21VM4
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the ferredoxin--NADP reductase type 2 family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

338969:RFER RS13295
gene id: 338969:RFER_RS13295
uniprot id: Q21V55
names: Similarity
messages: Belongs to the GST superfamily. NadH family.

338969:RFER RS01330
gene id: 338969:RFER_RS01330
uniprot id: Q222N2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

338969:RFER RS13095
gene id: 338969:RFER_RS13095
uniprot id: Q21V95
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

338969:RFER RS19500
gene id: 338969:RFER_RS19500
uniprot id: Q21RR4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AceK family.
messages: Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation.
messages: Cytoplasm

338969:RFER RS05095
gene id: 338969:RFER_RS05095
uniprot id: Q21ZP0
names: Similarity
messages: Belongs to the universal stress protein A family.

338969:RFER RS15975
gene id: 338969:RFER_RS15975
uniprot id: Q21TN8
names: Similarity
messages: Belongs to the UPF0434 family.

338969:RFER RS13615
gene id: 338969:RFER_RS13615
uniprot id: Q21UZ5
names: Similarity
messages: Belongs to the UPF0234 family.

338969:RFER RS18275
gene id: 338969:RFER_RS18275
uniprot id: Q21SE6
names: Similarity
names: Subunit
messages: Belongs to the threonine aldolase family.
messages: Homotetramer.

338969:RFER RS01025
gene id: 338969:RFER_RS01025
uniprot id: Q222U2
names: Similarity
messages: Belongs to the SAICAR synthetase family.

338969:RFER RS06715
gene id: 338969:RFER_RS06715
uniprot id: Q21YT2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-3 family.
messages: Cytoplasm
messages: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
messages: Monomer.

338969:RFER RS09755
gene id: 338969:RFER_RS09755
uniprot id: Q21X47
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Binds 1 copper ion per subunit, denoted as copper B.
messages: Binds 2 heme groups per subunit, denoted as high- and low-spin.
messages: Membrane

338969:RFER RS10930
gene id: 338969:RFER_RS10930
uniprot id: Q21WG7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

338969:RFER RS08250
gene id: 338969:RFER_RS08250
uniprot id: Q21XZ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

338969:RFER RS11930
gene id: 338969:RFER_RS11930
uniprot id: Q21VX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

338969:RFER RS15190
gene id: 338969:RFER_RS15190
uniprot id: Q21U37
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

338969:RFER RS06390
gene id: 338969:RFER_RS06390
uniprot id: Q21YZ6
names: Function
names: Similarity
messages: Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
messages: Belongs to the Nudix hydrolase family. RppH subfamily.

338969:RFER RS00255
gene id: 338969:RFER_RS00255
uniprot id: Q21QL4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.

338969:RFER RS06765
gene id: 338969:RFER_RS06765
uniprot id: Q21YS3
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

338969:RFER RS06455
gene id: 338969:RFER_RS06455
uniprot id: Q21YY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

338969:RFER RS00540
gene id: 338969:RFER_RS00540
uniprot id: Q223D5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

338969:RFER RS15770
gene id: 338969:RFER_RS15770
uniprot id: Q21TT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

338969:RFER RS16635
gene id: 338969:RFER_RS16635
uniprot id: Q21TA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

338969:RFER RS09060
gene id: 338969:RFER_RS09060
uniprot id: Q21XI5
names: Similarity
messages: Belongs to the TrpF family.

338969:RFER RS14985
gene id: 338969:RFER_RS14985
uniprot id: Q21U78
names: Cofactor
names: Function
names: Miscellaneous
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The Rieske protein is a high potential 2Fe-2S protein.
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

338969:RFER RS05665
gene id: 338969:RFER_RS05665
uniprot id: Q21ZD1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

338969:RFER RS16370
gene id: 338969:RFER_RS16370
uniprot id: Q21TG0
names: Similarity
messages: Belongs to the RecJ family.

338969:RFER RS10690
gene id: 338969:RFER_RS10690
uniprot id: Q21WL4
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

338969:RFER RS22965
gene id: 338969:RFER_RS22965
uniprot id: Q21XK6
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

338969:RFER RS17375
gene id: 338969:RFER_RS17375
uniprot id: Q21SW4
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

338969:RFER RS10945
gene id: 338969:RFER_RS10945
uniprot id: Q21WG3
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

338969:RFER RS19075
gene id: 338969:RFER_RS19075
uniprot id: Q21S00
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PNT beta subunit family.
messages: Cell inner membrane
messages: Membrane
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

338969:RFER RS10560
gene id: 338969:RFER_RS10560
uniprot id: Q21WN9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Lipid exporter (TC 3.A.1.106) family.
messages: Cell inner membrane
messages: Homodimer.
messages: In MsbA the ATP-binding domain (NBD) and the transmembrane domain (TMD) are fused.
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Translocates lipid A-core from the inner to the outer leaflet of the inner membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation.

338969:RFER RS00830
gene id: 338969:RFER_RS00830
uniprot id: Q222Y0
names: Similarity
messages: Belongs to the ABC transporter superfamily.

338969:RFER RS14110
gene id: 338969:RFER_RS14110
uniprot id: Q21UQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Membrane

338969:RFER RS16740
gene id: 338969:RFER_RS16740
uniprot id: Q21T87
names: Subcellular Location Annotation
messages: Periplasm

338969:RFER RS03005
gene id: 338969:RFER_RS03005
uniprot id: Q221E7
names: Subcellular Location Annotation
messages: Membrane

338969:RFER RS09955
gene id: 338969:RFER_RS09955
uniprot id: Q21X08
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

338969:RFER RS03215
gene id: 338969:RFER_RS03215
uniprot id: Q221A7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

338969:RFER RS00185
gene id: 338969:RFER_RS00185
uniprot id: Q223K9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MinC family.
messages: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.
messages: Interacts with MinD and FtsZ.

338969:RFER RS08210
gene id: 338969:RFER_RS08210
uniprot id: Q21Y01
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.

338969:RFER RS14135
gene id: 338969:RFER_RS14135
uniprot id: Q21UP6
names: Subcellular Location Annotation
messages: Membrane

338969:RFER RS07900
gene id: 338969:RFER_RS07900
uniprot id: Q21Y58
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LapB family.
messages: Cell inner membrane
messages: Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane.

338969:RFER RS05805
gene id: 338969:RFER_RS05805
uniprot id: Q21V14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

338969:RFER RS02210
gene id: 338969:RFER_RS02210
uniprot id: Q221V8
names: Similarity
messages: Belongs to the hyi family.

338969:RFER RS19050
gene id: 338969:RFER_RS19050
uniprot id: Q21S05
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

338969:RFER RS12895
gene id: 338969:RFER_RS12895
uniprot id: Q21VD4
names: Similarity
messages: Belongs to the glyoxalase I family.

338969:RFER RS12810
gene id: 338969:RFER_RS12810
uniprot id: Q21VF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

338969:RFER RS00320
gene id: 338969:RFER_RS00320
uniprot id: Q223M8
names: Similarity
messages: Belongs to the FeoA family.

338969:RFER RS20285
gene id: 338969:RFER_RS20285
uniprot id: Q21RA4
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

338969:RFER RS09840
gene id: 338969:RFER_RS09840
uniprot id: Q21X31
names: Similarity
messages: Belongs to the UPF0166 family.

338969:RFER RS03760
gene id: 338969:RFER_RS03760
uniprot id: Q220P7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

338969:RFER RS04830
gene id: 338969:RFER_RS04830
uniprot id: Q21ZU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

338969:RFER RS05565
gene id: 338969:RFER_RS05565
uniprot id: Q21ZF1
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

338969:RFER RS03135
gene id: 338969:RFER_RS03135
uniprot id: Q221C2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

338969:RFER RS02090
gene id: 338969:RFER_RS02090
uniprot id: Q221Y0
names: Subcellular Location Annotation
messages: Membrane

338969:RFER RS16070
gene id: 338969:RFER_RS16070
uniprot id: Q21TL9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M32 family.
messages: Binds 1 zinc ion per subunit.
messages: Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues.

338969:RFER RS10970
gene id: 338969:RFER_RS10970
uniprot id: Q21WF8
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

338969:RFER RS06760
gene id: 338969:RFER_RS06760
uniprot id: Q21YS4
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

338969:RFER RS17325
gene id: 338969:RFER_RS17325
uniprot id: Q21SX2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsQ/DivIB family. FtsQ subfamily.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly.
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

338969:RFER RS18865
gene id: 338969:RFER_RS18865
uniprot id: Q21S41
names: Function
names: Similarity
messages: Belongs to the FlgM family.
messages: Responsible for the coupling of flagellin expression to flagellar assembly by preventing expression of the flagellin genes when a component of the middle class of proteins is defective. It negatively regulates flagellar genes by inhibiting the activity of FliA by directly binding to FliA.

338969:RFER RS09255
gene id: 338969:RFER_RS09255
uniprot id: Q21XE6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell inner membrane

338969:RFER RS17065
gene id: 338969:RFER_RS17065
uniprot id: Q21T23
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. MrdB/RodA subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell wall elongation.

338969:RFER RS01125
gene id: 338969:RFER_RS01125
uniprot id: Q222S3
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

338969:RFER RS11560
gene id: 338969:RFER_RS11560
uniprot id: Q21W45
names: Similarity
messages: Belongs to the UPF0125 (RnfH) family.

338969:RFER RS21480
gene id: 338969:RFER_RS21480
uniprot id: Q21QM5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.

338969:RFER RS05310
gene id: 338969:RFER_RS05310
uniprot id: Q21ZK2
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

338969:RFER RS14700
gene id: 338969:RFER_RS14700
uniprot id: Q21UD6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ZapD family.
messages: Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity.
messages: Cytoplasm
messages: Interacts with FtsZ.

338969:RFER RS04265
gene id: 338969:RFER_RS04265
uniprot id: Q220E8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

338969:RFER RS08490
gene id: 338969:RFER_RS08490
uniprot id: Q21XU6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.

338969:RFER RS18775
gene id: 338969:RFER_RS18775
uniprot id: Q21S59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GmhB family.
messages: Cytoplasm

338969:RFER RS11030
gene id: 338969:RFER_RS11030
uniprot id: Q21WE6
names: Function
names: Subunit
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease.

338969:RFER RS02070
gene id: 338969:RFER_RS02070
uniprot id: Q221Y4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsbB family. BdbC subfamily.
messages: Membrane

338969:RFER RS18905
gene id: 338969:RFER_RS18905
uniprot id: Q21S33
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgH family.
messages: Cell outer membrane
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

338969:RFER RS03050
gene id: 338969:RFER_RS03050
uniprot id: Q221D8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

338969:RFER RS13155
gene id: 338969:RFER_RS13155
uniprot id: Q21V83
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

338969:RFER RS03585
gene id: 338969:RFER_RS03585
uniprot id: Q220T2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

338969:RFER RS13480
gene id: 338969:RFER_RS13480
uniprot id: Q21V18
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

338969:RFER RS11150
gene id: 338969:RFER_RS11150
uniprot id: Q21WC3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
messages: Homodimer.

338969:RFER RS08360
gene id: 338969:RFER_RS08360
uniprot id: Q21XX1
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

338969:RFER RS17725
gene id: 338969:RFER_RS17725
uniprot id: Q21SQ0
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

338969:RFER RS12520
gene id: 338969:RFER_RS12520
uniprot id: Q21VK8
names: Similarity
messages: Belongs to the TPP enzyme family.

338969:RFER RS05240
gene id: 338969:RFER_RS05240
uniprot id: Q21ZL4
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

338969:RFER RS11680
gene id: 338969:RFER_RS11680
uniprot id: Q21W21
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

338969:RFER RS20020
gene id: 338969:RFER_RS20020
uniprot id: Q21RF7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

338969:RFER RS15965
gene id: 338969:RFER_RS15965
uniprot id: Q21TP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

338969:RFER RS21365
gene id: 338969:RFER_RS21365
uniprot id: Q21QQ0
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

338969:RFER RS22330
gene id: 338969:RFER_RS22330
uniprot id: Q21Q57
names: Similarity
messages: Belongs to the bacterial secretin family.

338969:RFER RS09360
gene id: 338969:RFER_RS09360
uniprot id: Q21XC5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

338969:RFER RS13275
gene id: 338969:RFER_RS13275
uniprot id: Q21V59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

338969:RFER RS21885
gene id: 338969:RFER_RS21885
uniprot id: Q21QE0
names: Similarity
messages: Belongs to the DNA/RNA non-specific endonuclease family.

338969:RFER RS04420
gene id: 338969:RFER_RS04420
uniprot id: Q220B7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

338969:RFER RS05040
gene id: 338969:RFER_RS05040
uniprot id: Q21ZQ1
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

338969:RFER RS06380
gene id: 338969:RFER_RS06380
uniprot id: Q21YZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

338969:RFER RS05530
gene id: 338969:RFER_RS05530
uniprot id: Q21ZF8
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

338969:RFER RS14925
gene id: 338969:RFER_RS14925
uniprot id: Q21U90
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

338969:RFER RS01380
gene id: 338969:RFER_RS01380
uniprot id: Q222M2
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

338969:RFER RS11455
gene id: 338969:RFER_RS11455
uniprot id: Q21W63
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

338969:RFER RS14530
gene id: 338969:RFER_RS14530
uniprot id: Q21UH0
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.

338969:RFER RS19975
gene id: 338969:RFER_RS19975
uniprot id: Q21RG6
names: Similarity
messages: Belongs to the GSP E family.

338969:RFER RS09095
gene id: 338969:RFER_RS09095
uniprot id: Q21XH8
names: Similarity
messages: Belongs to the citrate synthase family.

338969:RFER RS11815
gene id: 338969:RFER_RS11815
uniprot id: Q21VZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

338969:RFER RS15970
gene id: 338969:RFER_RS15970
uniprot id: Q21TN9
names: Function
names: Similarity
messages: Belongs to the LpxK family.
messages: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

338969:RFER RS04000
gene id: 338969:RFER_RS04000
uniprot id: Q220K2
names: Subcellular Location Annotation
messages: Membrane

338969:RFER RS02695
gene id: 338969:RFER_RS02695
uniprot id: Q221K9
names: Similarity
messages: Belongs to the GSP E family.

338969:RFER RS06525
gene id: 338969:RFER_RS06525
uniprot id: Q21YW9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase D family. Cardiolipin synthase subfamily. ClsB sub-subfamily.
messages: Catalyzes the phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
messages: Cell membrane

338969:RFER RS13670
gene id: 338969:RFER_RS13670
uniprot id: Q21UY5
names: Similarity
messages: Belongs to the peptidase M1 family.

338969:RFER RS03555
gene id: 338969:RFER_RS03555
uniprot id: Q220T8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

338969:RFER RS10740
gene id: 338969:RFER_RS10740
uniprot id: Q21WK5
names: Similarity
messages: Belongs to the band 7/mec-2 family.

338969:RFER RS19930
gene id: 338969:RFER_RS19930
uniprot id: Q21RH5
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

338969:RFER RS12980
gene id: 338969:RFER_RS12980
uniprot id: Q21VB7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

338969:RFER RS09710
gene id: 338969:RFER_RS09710
uniprot id: Q21X56
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.

338969:RFER RS18200
gene id: 338969:RFER_RS18200
uniprot id: Q21SF6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

338969:RFER RS15125
gene id: 338969:RFER_RS15125
uniprot id: Q21U51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0761 family.
messages: Cell inner membrane

338969:RFER RS08915
gene id: 338969:RFER_RS08915
uniprot id: Q21XL3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import.
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

338969:RFER RS05820
gene id: 338969:RFER_RS05820
uniprot id: Q21ZA6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

338969:RFER RS03560
gene id: 338969:RFER_RS03560
uniprot id: Q220T7
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

338969:RFER RS20505
gene id: 338969:RFER_RS20505
uniprot id: Q21R59
names: Similarity
messages: Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.

338969:RFER RS00750
gene id: 338969:RFER_RS00750
uniprot id: Q222Z5
names: Function
names: Similarity
messages: Belongs to the ribose 1,5-bisphosphokinase family.
messages: Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP).

338969:RFER RS08395
gene id: 338969:RFER_RS08395
uniprot id: Q21XW4
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

338969:RFER RS10805
gene id: 338969:RFER_RS10805
uniprot id: Q21WJ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

338969:RFER RS14795
gene id: 338969:RFER_RS14795
uniprot id: Q21UB6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm

338969:RFER RS02560
gene id: 338969:RFER_RS02560
uniprot id: Q221N6
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

338969:RFER RS12750
gene id: 338969:RFER_RS12750
uniprot id: Q21VG3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

338969:RFER RS00195
gene id: 338969:RFER_RS00195
uniprot id: Q223K7
names: Function
names: Similarity
messages: Belongs to the CcmH/CycL/Ccl2/NrfF family.
messages: Possible subunit of a heme lyase.

338969:RFER RS07530
gene id: 338969:RFER_RS07530
uniprot id: Q21YC5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 30 kDa subunit family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

338969:RFER RS00965
gene id: 338969:RFER_RS00965
uniprot id: Q222V3
names: Subcellular Location Annotation
messages: Membrane

338969:RFER RS13890
gene id: 338969:RFER_RS13890
uniprot id: Q21UU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

338969:RFER RS16610
gene id: 338969:RFER_RS16610
uniprot id: Q21TB3
names: Similarity
messages: Belongs to the FrhG family.

338969:RFER RS17990
gene id: 338969:RFER_RS17990
uniprot id: Q21SJ7
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

338969:RFER RS11140
gene id: 338969:RFER_RS11140
uniprot id: Q21WC5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

338969:RFER RS12105
gene id: 338969:RFER_RS12105
uniprot id: Q21VT9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YciB family.
messages: Cell inner membrane
messages: Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.

338969:RFER RS02265
gene id: 338969:RFER_RS02265
uniprot id: Q221U7
names: Similarity
messages: Belongs to the 4-hydroxy-2-oxovalerate aldolase family.

338969:RFER RS07195
gene id: 338969:RFER_RS07195
uniprot id: Q21YI9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell inner membrane
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

338969:RFER RS15805
gene id: 338969:RFER_RS15805
uniprot id: Q21TS3
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

338969:RFER RS14910
gene id: 338969:RFER_RS14910
uniprot id: Q21U93
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

338969:RFER RS17365
gene id: 338969:RFER_RS17365
uniprot id: Q21SW5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

338969:RFER RS19280
gene id: 338969:RFER_RS19280
uniprot id: Q21RV9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

338969:RFER RS19205
gene id: 338969:RFER_RS19205
uniprot id: Q21RX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

338969:RFER RS16075
gene id: 338969:RFER_RS16075
uniprot id: Q21TL8
names: Function
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.
messages: DNA-dependent ATPase that plays important roles in cellular responses to stalled DNA replication processes.

338969:RFER RS11550
gene id: 338969:RFER_RS11550
uniprot id: Q21W47
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

338969:RFER RS10635
gene id: 338969:RFER_RS10635
uniprot id: Q21WM4
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetyltransferase family. ArgA subfamily.
messages: Cytoplasm
messages: In bacteria which possess the bifunctional enzyme ornithine acetyltransferase/N-acetylglutamate synthase (ArgJ), ArgA fulfills an anaplerotic role.

338969:RFER RS03685
gene id: 338969:RFER_RS03685
uniprot id: Q220R2
names: Similarity
messages: Belongs to the peptidase C40 family.

338969:RFER RS01990
gene id: 338969:RFER_RS01990
uniprot id: Q222A0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

338969:RFER RS04815
gene id: 338969:RFER_RS04815
uniprot id: Q21ZU5
names: Similarity
messages: Belongs to the DSD1 family.

338969:RFER RS15945
gene id: 338969:RFER_RS15945
uniprot id: Q21TP4
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family. GreB subfamily.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length.

338969:RFER RS19840
gene id: 338969:RFER_RS19840
uniprot id: Q21RJ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

338969:RFER RS15570
gene id: 338969:RFER_RS15570
uniprot id: Q21TW6
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

338969:RFER RS08975
gene id: 338969:RFER_RS08975
uniprot id: Q21XK2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Methionine importer (TC 3.A.1.24) family.
messages: Cell inner membrane
messages: Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (MetN), two transmembrane proteins (MetI) and a solute-binding protein (MetQ).

338969:RFER RS22315
gene id: 338969:RFER_RS22315
uniprot id: Q21Q60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

338969:RFER RS00925
gene id: 338969:RFER_RS00925
uniprot id: Q222W1
names: Similarity
messages: Belongs to the phosphate/phosphite/phosphonate binding protein family.

338969:RFER RS08560
gene id: 338969:RFER_RS08560
uniprot id: Q21XT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

338969:RFER RS18085
gene id: 338969:RFER_RS18085
uniprot id: Q21SH8
names: Similarity
messages: Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily.

338969:RFER RS17635
gene id: 338969:RFER_RS17635
uniprot id: Q21SR7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

338969:RFER RS10720
gene id: 338969:RFER_RS10720
uniprot id: Q21WK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

338969:RFER RS15905
gene id: 338969:RFER_RS15905
uniprot id: Q21TQ2
names: Similarity
messages: Belongs to the LOG family.

338969:RFER RS17830
gene id: 338969:RFER_RS17830
uniprot id: Q21SM9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

338969:RFER RS08405
gene id: 338969:RFER_RS08405
uniprot id: Q21XW3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

338969:RFER RS08760
gene id: 338969:RFER_RS08760
uniprot id: Q21XP4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

338969:RFER RS03250
gene id: 338969:RFER_RS03250
uniprot id: Q221A0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

338969:RFER RS23145
gene id: 338969:RFER_RS23145
uniprot id: Q21R50
names: Subcellular Location Annotation
messages: Membrane

338969:RFER RS11625
gene id: 338969:RFER_RS11625
uniprot id: Q21W32
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

338969:RFER RS07090
gene id: 338969:RFER_RS07090
uniprot id: Q21YL0
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

338969:RFER RS07690
gene id: 338969:RFER_RS07690
uniprot id: Q21Y94
names: Subcellular Location Annotation
messages: Membrane

338969:RFER RS15050
gene id: 338969:RFER_RS15050
uniprot id: Q21U66
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

338969:RFER RS06165
gene id: 338969:RFER_RS06165
uniprot id: Q21Z42
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. DnaE2 subfamily.
messages: Cytoplasm
messages: DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase.

338969:RFER RS18890
gene id: 338969:RFER_RS18890
uniprot id: Q21S36
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

338969:RFER RS15930
gene id: 338969:RFER_RS15930
uniprot id: Q21TP7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

338969:RFER RS00350
gene id: 338969:RFER_RS00350
uniprot id: Q223M1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

338969:RFER RS17705
gene id: 338969:RFER_RS17705
uniprot id: Q21SQ4
names: Subcellular Location Annotation
messages: Membrane

338969:RFER RS13100
gene id: 338969:RFER_RS13100
uniprot id: Q21V94
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

338969:RFER RS16660
gene id: 338969:RFER_RS16660
uniprot id: Q21TA3
names: Subcellular Location Annotation
messages: Membrane

338969:RFER RS00200
gene id: 338969:RFER_RS00200
uniprot id: Q223K6
names: Similarity
messages: Belongs to the thioredoxin family. DsbE subfamily.

338969:RFER RS13375
gene id: 338969:RFER_RS13375
uniprot id: Q21V39
names: Activity Regulation
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.

338969:RFER RS15935
gene id: 338969:RFER_RS15935
uniprot id: Q21TP6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

338969:RFER RS08605
gene id: 338969:RFER_RS08605
uniprot id: Q21XS3
names: Similarity
messages: Belongs to the P(II) protein family.

338969:RFER RS14915
gene id: 338969:RFER_RS14915
uniprot id: Q21U92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

338969:RFER RS02360
gene id: 338969:RFER_RS02360
uniprot id: Q221S7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

338969:RFER RS19080
gene id: 338969:RFER_RS19080
uniprot id: Q21RZ9
names: Function
names: Similarity
messages: Belongs to the AlaDH/PNT family.
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

338969:RFER RS21500
gene id: 338969:RFER_RS21500
uniprot id: Q21QM1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.