335992:SAR11 RS05750
gene id: 335992:SAR11_RS05750
uniprot id: Q4FLI9
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.

335992:SAR11 RS05545
gene id: 335992:SAR11_RS05545
uniprot id: Q4FLM5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

335992:SAR11 RS06395
gene id: 335992:SAR11_RS06395
uniprot id: Q4FL57
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.

335992:SAR11 RS01990
gene id: 335992:SAR11_RS01990
uniprot id: Q4FNM1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thioester dehydratase family. FabA subfamily.
messages: Cytoplasm
messages: Homodimer.

335992:SAR11 RS02485
gene id: 335992:SAR11_RS02485
uniprot id: Q4FNC6
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

335992:SAR11 RS00220
gene id: 335992:SAR11_RS00220
uniprot id: Q4FPQ7
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

335992:SAR11 RS01100
gene id: 335992:SAR11_RS01100
uniprot id: Q4FP47
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

335992:SAR11 RS00810
gene id: 335992:SAR11_RS00810
uniprot id: Q4FPA6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

335992:SAR11 RS02545
gene id: 335992:SAR11_RS02545
uniprot id: Q4FNB4
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily.

335992:SAR11 RS06005
gene id: 335992:SAR11_RS06005
uniprot id: Q4FLD6
names: Subcellular Location Annotation
messages: Membrane

335992:SAR11 RS00795
gene id: 335992:SAR11_RS00795
uniprot id: Q4FPA9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

335992:SAR11 RS03570
gene id: 335992:SAR11_RS03570
uniprot id: Q4FMR4
names: Similarity
messages: Belongs to the fabD family.

335992:SAR11 RS04250
gene id: 335992:SAR11_RS04250
uniprot id: Q4FMC6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

335992:SAR11 RS05900
gene id: 335992:SAR11_RS05900
uniprot id: Q4FLF8
names: Function
messages: This protein is a positive regulator for the phosphate regulon. Transcription of this operon is positively regulated by PhoB and PhoR when phosphate is limited.

335992:SAR11 RS02815
gene id: 335992:SAR11_RS02815
uniprot id: Q4FN64
names: Similarity
messages: Belongs to the NodU/CmcH family.

335992:SAR11 RS04905
gene id: 335992:SAR11_RS04905
uniprot id: Q4FLZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

335992:SAR11 RS01575
gene id: 335992:SAR11_RS01575
uniprot id: Q4FNV3
names: Caution
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

335992:SAR11 RS03265
gene id: 335992:SAR11_RS03265
uniprot id: Q4FMX5
names: Cofactor
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

335992:SAR11 RS00670
gene id: 335992:SAR11_RS00670
uniprot id: Q4FPD4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COX11/CtaG family.
messages: Cell inner membrane
messages: Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I.

335992:SAR11 RS00260
gene id: 335992:SAR11_RS00260
uniprot id: Q4FPP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

335992:SAR11 RS01870
gene id: 335992:SAR11_RS01870
uniprot id: Q4FNP5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

335992:SAR11 RS01280
gene id: 335992:SAR11_RS01280
uniprot id: Q4FP11
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Cell inner membrane
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

335992:SAR11 RS02885
gene id: 335992:SAR11_RS02885
uniprot id: Q4FN49
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

335992:SAR11 RS03430
gene id: 335992:SAR11_RS03430
uniprot id: Q4FMU2
names: Function
names: Similarity
messages: Belongs to the SELO family.
messages: Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).

335992:SAR11 RS00045
gene id: 335992:SAR11_RS00045
uniprot id: Q4FPM7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. HflK subfamily.
messages: HflC and HflK could encode or regulate a protease.
messages: HflC and HflK may interact to form a multimeric complex.
messages: Membrane

335992:SAR11 RS06490
gene id: 335992:SAR11_RS06490
uniprot id: Q4FL38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

335992:SAR11 RS05985
gene id: 335992:SAR11_RS05985
uniprot id: Q4FLE0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

335992:SAR11 RS02300
gene id: 335992:SAR11_RS02300
uniprot id: Q4FNG0
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

335992:SAR11 RS05075
gene id: 335992:SAR11_RS05075
uniprot id: Q4FLW8
names: Function
names: Similarity
messages: Belongs to the polysaccharide deacetylase family.
messages: Is involved in generating a small heat-stable compound (Nod), an acylated oligomer of N-acetylglucosamine, that stimulates mitosis in various plant protoplasts.

335992:SAR11 RS01685
gene id: 335992:SAR11_RS01685
uniprot id: Q4FNT2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

335992:SAR11 RS01285
gene id: 335992:SAR11_RS01285
uniprot id: Q4FP10
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.

335992:SAR11 RS05025
gene id: 335992:SAR11_RS05025
uniprot id: Q4FLX6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

335992:SAR11 RS06465
gene id: 335992:SAR11_RS06465
uniprot id: Q4FL43
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.

335992:SAR11 RS04495
gene id: 335992:SAR11_RS04495
uniprot id: Q4FM79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

335992:SAR11 RS02340
gene id: 335992:SAR11_RS02340
uniprot id: Q4FNF2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

335992:SAR11 RS03385
gene id: 335992:SAR11_RS03385
uniprot id: Q4FMV1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

335992:SAR11 RS03690
gene id: 335992:SAR11_RS03690
uniprot id: Q4FMP0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

335992:SAR11 RS02225
gene id: 335992:SAR11_RS02225
uniprot id: Q4FNH5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

335992:SAR11 RS01165
gene id: 335992:SAR11_RS01165
uniprot id: Q4FP34
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

335992:SAR11 RS03900
gene id: 335992:SAR11_RS03900
uniprot id: Q4FMJ7
names: Similarity
messages: Belongs to the IlvD/Edd family.

335992:SAR11 RS02130
gene id: 335992:SAR11_RS02130
uniprot id: Q4FNJ3
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

335992:SAR11 RS02635
gene id: 335992:SAR11_RS02635
uniprot id: Q4FN96
names: Subcellular Location Annotation
messages: Membrane

335992:SAR11 RS02280
gene id: 335992:SAR11_RS02280
uniprot id: Q4FNG5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm

335992:SAR11 RS06315
gene id: 335992:SAR11_RS06315
uniprot id: Q4FL74
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

335992:SAR11 RS02325
gene id: 335992:SAR11_RS02325
uniprot id: Q4FNF5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M20A family. DapE subfamily.
messages: Binds 2 Zn(2+) or Co(2+) ions per subunit.
messages: Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
messages: Homodimer.

335992:SAR11 RS01955
gene id: 335992:SAR11_RS01955
uniprot id: Q4FNM8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

335992:SAR11 RS06655
gene id: 335992:SAR11_RS06655
uniprot id: Q4FL05
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

335992:SAR11 RS05695
gene id: 335992:SAR11_RS05695
uniprot id: Q4FLK0
names: Similarity
messages: Belongs to the SfsA family.

335992:SAR11 RS03085
gene id: 335992:SAR11_RS03085
uniprot id: Q4FN11
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

335992:SAR11 RS02175
gene id: 335992:SAR11_RS02175
uniprot id: Q4FNI5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell inner membrane

335992:SAR11 RS03610
gene id: 335992:SAR11_RS03610
uniprot id: Q4FMQ6
names: Subcellular Location Annotation
messages: Membrane

335992:SAR11 RS04995
gene id: 335992:SAR11_RS04995
uniprot id: Q4FLY2
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

335992:SAR11 RS01335
gene id: 335992:SAR11_RS01335
uniprot id: Q4FP00
names: Similarity
messages: Belongs to the ABC transporter superfamily.

335992:SAR11 RS00495
gene id: 335992:SAR11_RS00495
uniprot id: Q4FPG8
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

335992:SAR11 RS03555
gene id: 335992:SAR11_RS03555
uniprot id: Q4FMR7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

335992:SAR11 RS04650
gene id: 335992:SAR11_RS04650
uniprot id: Q4FM48
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

335992:SAR11 RS00980
gene id: 335992:SAR11_RS00980
uniprot id: Q4FP71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

335992:SAR11 RS03380
gene id: 335992:SAR11_RS03380
uniprot id: Q4FMV2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

335992:SAR11 RS00740
gene id: 335992:SAR11_RS00740
uniprot id: Q4FPC0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family.
messages: Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
messages: Cell inner membrane

335992:SAR11 RS06275
gene id: 335992:SAR11_RS06275
uniprot id: Q4FL82
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

335992:SAR11 RS04060
gene id: 335992:SAR11_RS04060
uniprot id: Q4FMG5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Taurine importer (TC 3.A.1.17.1) family.
messages: Cell inner membrane
messages: Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (TauB), two transmembrane proteins (TauC) and a solute-binding protein (TauA).

335992:SAR11 RS00590
gene id: 335992:SAR11_RS00590
uniprot id: Q4FPF0
names: Function
names: Similarity
messages: A possible function for this protein is to guide the assembly of the membrane sector of the ATPase enzyme complex.
messages: Belongs to the bacterial AtpI family.

335992:SAR11 RS05630
gene id: 335992:SAR11_RS05630
uniprot id: Q4FLK8
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

335992:SAR11 RS05525
gene id: 335992:SAR11_RS05525
uniprot id: Q4FLM9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

335992:SAR11 RS01185
gene id: 335992:SAR11_RS01185
uniprot id: Q4FP30
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

335992:SAR11 RS05345
gene id: 335992:SAR11_RS05345
uniprot id: Q4FLR5
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

335992:SAR11 RS00570
gene id: 335992:SAR11_RS00570
uniprot id: Q4FPF4
names: Function
names: Similarity
messages: Adenine glycosylase active on G-A mispairs. MutY also corrects error-prone DNA synthesis past GO lesions which are due to the oxidatively damaged form of guanine: 7,8-dihydro-8-oxoguanine (8-oxo-dGTP).
messages: Belongs to the Nth/MutY family.

335992:SAR11 RS03580
gene id: 335992:SAR11_RS03580
uniprot id: Q4FMR2
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

335992:SAR11 RS02185
gene id: 335992:SAR11_RS02185
uniprot id: Q4FNI3
names: Similarity
messages: Belongs to the glutamate synthase family.

335992:SAR11 RS06460
gene id: 335992:SAR11_RS06460
uniprot id: Q4FL44
names: Similarity
messages: Belongs to the bacterial solute-binding protein 7 family.

335992:SAR11 RS01815
gene id: 335992:SAR11_RS01815
uniprot id: Q4FNQ6
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

335992:SAR11 RS05240
gene id: 335992:SAR11_RS05240
uniprot id: Q4FLT5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

335992:SAR11 RS03960
gene id: 335992:SAR11_RS03960
uniprot id: Q4FMI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

335992:SAR11 RS02215
gene id: 335992:SAR11_RS02215
uniprot id: Q4FNH7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

335992:SAR11 RS01345
gene id: 335992:SAR11_RS01345
uniprot id: Q4FNZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

335992:SAR11 RS02075
gene id: 335992:SAR11_RS02075
uniprot id: Q4FNK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

335992:SAR11 RS00310
gene id: 335992:SAR11_RS00310
uniprot id: Q4FPL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial secretin family.
messages: Cell outer membrane

335992:SAR11 RS06695
gene id: 335992:SAR11_RS06695
uniprot id: Q4FKZ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
messages: Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD).

335992:SAR11 RS04580
gene id: 335992:SAR11_RS04580
uniprot id: Q4FM62
names: Similarity
messages: Belongs to the Skp family.

335992:SAR11 RS04405
gene id: 335992:SAR11_RS04405
uniprot id: Q4FM95
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

335992:SAR11 RS03620
gene id: 335992:SAR11_RS03620
uniprot id: Q4FMQ4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

335992:SAR11 RS05260
gene id: 335992:SAR11_RS05260
uniprot id: Q4FLT1
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

335992:SAR11 RS05715
gene id: 335992:SAR11_RS05715
uniprot id: Q4FLJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

335992:SAR11 RS05440
gene id: 335992:SAR11_RS05440
uniprot id: Q4FLP6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

335992:SAR11 RS00780
gene id: 335992:SAR11_RS00780
uniprot id: Q4FPB2
names: Similarity
messages: Belongs to the GPI family.

335992:SAR11 RS03275
gene id: 335992:SAR11_RS03275
uniprot id: Q4FMX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

335992:SAR11 RS02205
gene id: 335992:SAR11_RS02205
uniprot id: Q4FNH9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged L-seryl-tRNA(Thr).
messages: Cytoplasm
messages: Homodimer.

335992:SAR11 RS05700
gene id: 335992:SAR11_RS05700
uniprot id: Q4FLJ9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

335992:SAR11 RS03615
gene id: 335992:SAR11_RS03615
uniprot id: Q4FMQ5
names: Subcellular Location Annotation
messages: Membrane

335992:SAR11 RS02980
gene id: 335992:SAR11_RS02980
uniprot id: Q4FN32
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

335992:SAR11 RS05285
gene id: 335992:SAR11_RS05285
uniprot id: Q4FLS6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.

335992:SAR11 RS03245
gene id: 335992:SAR11_RS03245
uniprot id: Q4FMX9
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

335992:SAR11 RS01270
gene id: 335992:SAR11_RS01270
uniprot id: Q4FP13
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

335992:SAR11 RS00725
gene id: 335992:SAR11_RS00725
uniprot id: Q4FPC3
names: Similarity
messages: Belongs to the pirin family.

335992:SAR11 RS02435
gene id: 335992:SAR11_RS02435
uniprot id: Q4FND6
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

335992:SAR11 RS02610
gene id: 335992:SAR11_RS02610
uniprot id: Q4FNA1
names: Similarity
messages: Belongs to the aspartokinase family.

335992:SAR11 RS05550
gene id: 335992:SAR11_RS05550
uniprot id: Q4FLM4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

335992:SAR11 RS01740
gene id: 335992:SAR11_RS01740
uniprot id: Q4FNS1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

335992:SAR11 RS04380
gene id: 335992:SAR11_RS04380
uniprot id: Q4FMA0
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 5 (UDGb) family.

335992:SAR11 RS02155
gene id: 335992:SAR11_RS02155
uniprot id: Q4FNI9
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

335992:SAR11 RS04420
gene id: 335992:SAR11_RS04420
uniprot id: Q4FM92
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

335992:SAR11 RS01835
gene id: 335992:SAR11_RS01835
uniprot id: Q4FNQ2
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

335992:SAR11 RS00655
gene id: 335992:SAR11_RS00655
uniprot id: Q4FPD7
names: Similarity
messages: Belongs to the threonine synthase family.

335992:SAR11 RS05460
gene id: 335992:SAR11_RS05460
uniprot id: Q4FLP2
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

335992:SAR11 RS05455
gene id: 335992:SAR11_RS05455
uniprot id: Q4FLP3
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.

335992:SAR11 RS02465
gene id: 335992:SAR11_RS02465
uniprot id: Q4FND0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

335992:SAR11 RS03500
gene id: 335992:SAR11_RS03500
uniprot id: Q4FMS8
names: Similarity
messages: Belongs to the UPF0234 family.

335992:SAR11 RS02475
gene id: 335992:SAR11_RS02475
uniprot id: Q4FNC8
names: Similarity
messages: Belongs to the TrpF family.

335992:SAR11 RS05250
gene id: 335992:SAR11_RS05250
uniprot id: Q4FLT3
names: Similarity
messages: Belongs to the LacAB/RpiB family.

335992:SAR11 RS01465
gene id: 335992:SAR11_RS01465
uniprot id: Q4FNX4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.

335992:SAR11 RS04070
gene id: 335992:SAR11_RS04070
uniprot id: Q4FMG3
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

335992:SAR11 RS04975
gene id: 335992:SAR11_RS04975
uniprot id: Q4FLY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EamA transporter family.
messages: Membrane

335992:SAR11 RS00645
gene id: 335992:SAR11_RS00645
uniprot id: Q4FPD9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

335992:SAR11 RS05725
gene id: 335992:SAR11_RS05725
uniprot id: Q4FLJ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

335992:SAR11 RS02030
gene id: 335992:SAR11_RS02030
uniprot id: Q4FNL3
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

335992:SAR11 RS01765
gene id: 335992:SAR11_RS01765
uniprot id: Q4FNR6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

335992:SAR11 RS06605
gene id: 335992:SAR11_RS06605
uniprot id: Q4FL15
names: Similarity
messages: Belongs to the UPF0047 family.

335992:SAR11 RS05495
gene id: 335992:SAR11_RS05495
uniprot id: Q4FLN5
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

335992:SAR11 RS00205
gene id: 335992:SAR11_RS00205
uniprot id: Q4FPR0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

335992:SAR11 RS04010
gene id: 335992:SAR11_RS04010
uniprot id: Q4FMH5
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

335992:SAR11 RS05625
gene id: 335992:SAR11_RS05625
uniprot id: Q4FLK9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

335992:SAR11 RS00170
gene id: 335992:SAR11_RS00170
uniprot id: Q4FPN3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

335992:SAR11 RS05910
gene id: 335992:SAR11_RS05910
uniprot id: Q4FLF6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.
messages: Cell inner membrane
messages: Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

335992:SAR11 RS01545
gene id: 335992:SAR11_RS01545
uniprot id: Q4FNV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

335992:SAR11 RS04110
gene id: 335992:SAR11_RS04110
uniprot id: Q4FMF5
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

335992:SAR11 RS02940
gene id: 335992:SAR11_RS02940
uniprot id: Q4FN40
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

335992:SAR11 RS00050
gene id: 335992:SAR11_RS00050
uniprot id: Q4FPM6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

335992:SAR11 RS05775
gene id: 335992:SAR11_RS05775
uniprot id: Q4FLI4
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

335992:SAR11 RS03735
gene id: 335992:SAR11_RS03735
uniprot id: Q4FMN1
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

335992:SAR11 RS04690
gene id: 335992:SAR11_RS04690
uniprot id: Q4FM39
names: Activity Regulation
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.

335992:SAR11 RS04545
gene id: 335992:SAR11_RS04545
uniprot id: Q4FM69
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

335992:SAR11 RS01420
gene id: 335992:SAR11_RS01420
uniprot id: Q4FNY3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmE/CycJ family.
messages: Cell inner membrane
messages: Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.

335992:SAR11 RS00910
gene id: 335992:SAR11_RS00910
uniprot id: Q4FP85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

335992:SAR11 RS04335
gene id: 335992:SAR11_RS04335
uniprot id: Q4FMA9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial solute-binding protein 7 family.
messages: Homodimer.
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: Periplasm

335992:SAR11 RS04305
gene id: 335992:SAR11_RS04305
uniprot id: Q4FMB5
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

335992:SAR11 RS04135
gene id: 335992:SAR11_RS04135
uniprot id: Q4FMF0
names: Similarity
messages: Belongs to the GST superfamily. NadH family.

335992:SAR11 RS00120
gene id: 335992:SAR11_RS00120
uniprot id: Q4FPK6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

335992:SAR11 RS01120
gene id: 335992:SAR11_RS01120
uniprot id: Q4FP43
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

335992:SAR11 RS02460
gene id: 335992:SAR11_RS02460
uniprot id: Q4FND1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm
messages: The spacing between the first 2 Cys is very close; it may not bind zinc.

335992:SAR11 RS05265
gene id: 335992:SAR11_RS05265
uniprot id: Q4FLT0
names: Similarity
messages: Belongs to the RecO family.

335992:SAR11 RS04360
gene id: 335992:SAR11_RS04360
uniprot id: Q4FMA4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

335992:SAR11 RS04095
gene id: 335992:SAR11_RS04095
uniprot id: Q4FMF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

335992:SAR11 RS00630
gene id: 335992:SAR11_RS00630
uniprot id: Q4FPE2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Brp/Blh beta-carotene diooxygenase family.
messages: Catalyzes the cleavage of beta-carotene at its central double bond (15,15') to yield two molecules of all-trans-retinal.
messages: Cell membrane

335992:SAR11 RS04460
gene id: 335992:SAR11_RS04460
uniprot id: Q4FM86
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

335992:SAR11 RS04710
gene id: 335992:SAR11_RS04710
uniprot id: Q4FM35
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

335992:SAR11 RS04490
gene id: 335992:SAR11_RS04490
uniprot id: Q4FM80
names: Subcellular Location Annotation
messages: Membrane
messages: Mitochondrion inner membrane

335992:SAR11 RS04575
gene id: 335992:SAR11_RS04575
uniprot id: Q4FM63
names: Subcellular Location Annotation
messages: Cell outer membrane

335992:SAR11 RS06305
gene id: 335992:SAR11_RS06305
uniprot id: Q4FL76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0394 family.
messages: Membrane

335992:SAR11 RS05145
gene id: 335992:SAR11_RS05145
uniprot id: Q4FLV4
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

335992:SAR11 RS05565
gene id: 335992:SAR11_RS05565
uniprot id: Q4FLM1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

335992:SAR11 RS03035
gene id: 335992:SAR11_RS03035
uniprot id: Q4FN21
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TolB family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: Periplasm
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

335992:SAR11 RS05305
gene id: 335992:SAR11_RS05305
uniprot id: Q4FLS2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

335992:SAR11 RS06140
gene id: 335992:SAR11_RS06140
uniprot id: Q4FLB1
names: Similarity
messages: Belongs to the GcvT family.

335992:SAR11 RS01065
gene id: 335992:SAR11_RS01065
uniprot id: Q4FP54
names: Similarity
messages: Belongs to the peptidase C40 family.

335992:SAR11 RS02970
gene id: 335992:SAR11_RS02970
uniprot id: Q4FN34
names: Similarity
messages: Belongs to the class I fructose-bisphosphate aldolase family.

335992:SAR11 RS03145
gene id: 335992:SAR11_RS03145
uniprot id: Q4FN00
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the reversible phosphorylation of pyruvate and phosphate.

335992:SAR11 RS01140
gene id: 335992:SAR11_RS01140
uniprot id: Q4FP39
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

335992:SAR11 RS02400
gene id: 335992:SAR11_RS02400
uniprot id: Q4FNE1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

335992:SAR11 RS03055
gene id: 335992:SAR11_RS03055
uniprot id: Q4FN17
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

335992:SAR11 RS01940
gene id: 335992:SAR11_RS01940
uniprot id: Q4FNN1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

335992:SAR11 RS05210
gene id: 335992:SAR11_RS05210
uniprot id: Q4FLU1
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

335992:SAR11 RS05395
gene id: 335992:SAR11_RS05395
uniprot id: Q4FLQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF nuclease family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

335992:SAR11 RS00615
gene id: 335992:SAR11_RS00615
uniprot id: Q4FPE5
names: Similarity
messages: Belongs to the carotenoid/retinoid oxidoreductase family.

335992:SAR11 RS05300
gene id: 335992:SAR11_RS05300
uniprot id: Q4FLS3
names: Function
names: Similarity
messages: Belongs to the HPPK family.
messages: Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.

335992:SAR11 RS03930
gene id: 335992:SAR11_RS03930
uniprot id: Q4FMJ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PEPCase type 1 family.
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
messages: Homotetramer.

335992:SAR11 RS00110
gene id: 335992:SAR11_RS00110
uniprot id: Q4FPK8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

335992:SAR11 RS04775
gene id: 335992:SAR11_RS04775
uniprot id: Q4FM23
names: Similarity
messages: Belongs to the ABC transporter superfamily.

335992:SAR11 RS01750
gene id: 335992:SAR11_RS01750
uniprot id: Q4FNR9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

335992:SAR11 RS00945
gene id: 335992:SAR11_RS00945
uniprot id: Q4FP78
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

335992:SAR11 RS05280
gene id: 335992:SAR11_RS05280
uniprot id: Q4FLS7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

335992:SAR11 RS00815
gene id: 335992:SAR11_RS00815
uniprot id: Q4FPA5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

335992:SAR11 RS06680
gene id: 335992:SAR11_RS06680
uniprot id: Q4FL00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

335992:SAR11 RS06270
gene id: 335992:SAR11_RS06270
uniprot id: Q4FL83
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

335992:SAR11 RS00680
gene id: 335992:SAR11_RS00680
uniprot id: Q4FPD2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell inner membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.

335992:SAR11 RS03565
gene id: 335992:SAR11_RS03565
uniprot id: Q4FMR5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

335992:SAR11 RS06420
gene id: 335992:SAR11_RS06420
uniprot id: Q4FL52
names: Similarity
messages: Belongs to the GcvT family.

335992:SAR11 RS00485
gene id: 335992:SAR11_RS00485
uniprot id: Q4FPH0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

335992:SAR11 RS05915
gene id: 335992:SAR11_RS05915
uniprot id: Q4FLF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Membrane

335992:SAR11 RS00665
gene id: 335992:SAR11_RS00665
uniprot id: Q4FPD5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

335992:SAR11 RS01760
gene id: 335992:SAR11_RS01760
uniprot id: Q4FNR7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.

335992:SAR11 RS00040
gene id: 335992:SAR11_RS00040
uniprot id: Q4FPM8
names: Function
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflC subfamily.
messages: HflC and HflK could regulate a protease.

335992:SAR11 RS04735
gene id: 335992:SAR11_RS04735
uniprot id: Q4FM30
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

335992:SAR11 RS05225
gene id: 335992:SAR11_RS05225
uniprot id: Q4FLT8
names: Function
names: Similarity
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

335992:SAR11 RS06240
gene id: 335992:SAR11_RS06240
uniprot id: Q4FL89
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Toroid-shaped homodecamer, composed of two pentamers of five dimers.

335992:SAR11 RS03680
gene id: 335992:SAR11_RS03680
uniprot id: Q4FMP2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

335992:SAR11 RS03630
gene id: 335992:SAR11_RS03630
uniprot id: Q4FMQ2
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

335992:SAR11 RS01615
gene id: 335992:SAR11_RS01615
uniprot id: Q4FNU5
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

335992:SAR11 RS04470
gene id: 335992:SAR11_RS04470
uniprot id: Q4FM84
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

335992:SAR11 RS01415
gene id: 335992:SAR11_RS01415
uniprot id: Q4FNY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
messages: Cell inner membrane
messages: Membrane

335992:SAR11 RS04560
gene id: 335992:SAR11_RS04560
uniprot id: Q4FM66
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

335992:SAR11 RS01115
gene id: 335992:SAR11_RS01115
uniprot id: Q4FP44
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

335992:SAR11 RS04920
gene id: 335992:SAR11_RS04920
uniprot id: Q4FLZ6
names: Function
names: Subunit
messages: Homotetramer.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

335992:SAR11 RS04730
gene id: 335992:SAR11_RS04730
uniprot id: Q4FM31
names: Function
names: Similarity
messages: Bifunctional enzyme that catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF).
messages: In the C-terminal section; belongs to the IspF family.
messages: In the N-terminal section; belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.

335992:SAR11 RS03635
gene id: 335992:SAR11_RS03635
uniprot id: Q4FMQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

335992:SAR11 RS05390
gene id: 335992:SAR11_RS05390
uniprot id: Q4FLQ6
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

335992:SAR11 RS02050
gene id: 335992:SAR11_RS02050
uniprot id: Q4FNK9
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

335992:SAR11 RS01985
gene id: 335992:SAR11_RS01985
uniprot id: Q4FNM2
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

335992:SAR11 RS03770
gene id: 335992:SAR11_RS03770
uniprot id: Q4FMM3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia.
messages: Oligomer of 12 subunits arranged in the form of two hexameric ring.

335992:SAR11 RS06370
gene id: 335992:SAR11_RS06370
uniprot id: Q4FL62
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.

335992:SAR11 RS01550
gene id: 335992:SAR11_RS01550
uniprot id: Q4FNV8
names: Function
names: Similarity
messages: Belongs to the uroporphyrinogen-III synthase family.
messages: Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.

335992:SAR11 RS04055
gene id: 335992:SAR11_RS04055
uniprot id: Q4FMG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

335992:SAR11 RS02385
gene id: 335992:SAR11_RS02385
uniprot id: Q4FNE4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm

335992:SAR11 RS03720
gene id: 335992:SAR11_RS03720
uniprot id: Q4FMN4
names: Function
names: Similarity
messages: Belongs to the anhydro-N-acetylmuramic acid kinase family.
messages: Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.

335992:SAR11 RS06000
gene id: 335992:SAR11_RS06000
uniprot id: Q4FLD7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

335992:SAR11 RS04105
gene id: 335992:SAR11_RS04105
uniprot id: Q4FMF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

335992:SAR11 RS04500
gene id: 335992:SAR11_RS04500
uniprot id: Q4FM78
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

335992:SAR11 RS03235
gene id: 335992:SAR11_RS03235
uniprot id: Q4FMY1
names: Similarity
messages: Belongs to the Gfa family.

335992:SAR11 RS01205
gene id: 335992:SAR11_RS01205
uniprot id: Q4FP26
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur, cytochrome b-556, and a hydrophobic anchor protein.

335992:SAR11 RS03330
gene id: 335992:SAR11_RS03330
uniprot id: Q4FMW2
names: Subcellular Location Annotation
messages: Membrane

335992:SAR11 RS06200
gene id: 335992:SAR11_RS06200
uniprot id: Q4FL99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

335992:SAR11 RS04840
gene id: 335992:SAR11_RS04840
uniprot id: Q4FM12
names: Similarity
messages: Belongs to the HesB/IscA family.

335992:SAR11 RS04940
gene id: 335992:SAR11_RS04940
uniprot id: Q4FLZ2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

335992:SAR11 RS01675
gene id: 335992:SAR11_RS01675
uniprot id: Q4FNT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

335992:SAR11 RS04930
gene id: 335992:SAR11_RS04930
uniprot id: Q4FLZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

335992:SAR11 RS00540
gene id: 335992:SAR11_RS00540
uniprot id: Q4FPG0
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

335992:SAR11 RS00250
gene id: 335992:SAR11_RS00250
uniprot id: Q4FPP7
names: Subcellular Location Annotation
messages: Membrane

335992:SAR11 RS01190
gene id: 335992:SAR11_RS01190
uniprot id: Q4FP29
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

335992:SAR11 RS00165
gene id: 335992:SAR11_RS00165
uniprot id: Q4FPN4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

335992:SAR11 RS00285
gene id: 335992:SAR11_RS00285
uniprot id: Q4FPP0
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

335992:SAR11 RS00395
gene id: 335992:SAR11_RS00395
uniprot id: Q4FPI8
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

335992:SAR11 RS00140
gene id: 335992:SAR11_RS00140
uniprot id: Q4FPK2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell inner membrane

335992:SAR11 RS05160
gene id: 335992:SAR11_RS05160
uniprot id: Q4FLV1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COX15/CtaA family. Type 2 subfamily.
messages: Catalyzes the conversion of heme O to heme A by two successive hydroxylations of the methyl group at C8. The first hydroxylation forms heme I, the second hydroxylation results in an unstable dihydroxymethyl group, which spontaneously dehydrates, resulting in the formyl group of heme A.
messages: Cell membrane
messages: Interacts with CtaB.

335992:SAR11 RS04960
gene id: 335992:SAR11_RS04960
uniprot id: Q4FLY8
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.

335992:SAR11 RS06740
gene id: 335992:SAR11_RS06740
uniprot id: Q4FKY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

335992:SAR11 RS03545
gene id: 335992:SAR11_RS03545
uniprot id: Q4FMR9
names: Subcellular Location Annotation
messages: Membrane

335992:SAR11 RS00875
gene id: 335992:SAR11_RS00875
uniprot id: Q4FP92
names: Similarity
messages: Belongs to the DapA family.

335992:SAR11 RS02315
gene id: 335992:SAR11_RS02315
uniprot id: Q4FNF7
names: Similarity
messages: Belongs to the histone deacetylase family.

335992:SAR11 RS03190
gene id: 335992:SAR11_RS03190
uniprot id: Q4FMZ1
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the ferredoxin--NADP reductase type 2 family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

335992:SAR11 RS03515
gene id: 335992:SAR11_RS03515
uniprot id: Q4FMS5
names: Subcellular Location Annotation
messages: Membrane

335992:SAR11 RS05130
gene id: 335992:SAR11_RS05130
uniprot id: Q4FLV7
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

335992:SAR11 RS00400
gene id: 335992:SAR11_RS00400
uniprot id: Q4FPI7
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

335992:SAR11 RS05745
gene id: 335992:SAR11_RS05745
uniprot id: Q4FLJ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

335992:SAR11 RS06450
gene id: 335992:SAR11_RS06450
uniprot id: Q4FL46
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

335992:SAR11 RS06745
gene id: 335992:SAR11_RS06745
uniprot id: Q4FKY7
names: Subcellular Location Annotation
messages: Membrane

335992:SAR11 RS01590
gene id: 335992:SAR11_RS01590
uniprot id: Q4FNV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

335992:SAR11 RS00015
gene id: 335992:SAR11_RS00015
uniprot id: Q4FPQ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

335992:SAR11 RS03010
gene id: 335992:SAR11_RS03010
uniprot id: Q4FN26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

335992:SAR11 RS04900
gene id: 335992:SAR11_RS04900
uniprot id: Q4FM00
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

335992:SAR11 RS00965
gene id: 335992:SAR11_RS00965
uniprot id: Q4FP74
names: Function
names: Similarity
names: Subunit
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Homodimer.

335992:SAR11 RS01680
gene id: 335992:SAR11_RS01680
uniprot id: Q4FNT3
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

335992:SAR11 RS05590
gene id: 335992:SAR11_RS05590
uniprot id: Q4FLL6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

335992:SAR11 RS02430
gene id: 335992:SAR11_RS02430
uniprot id: Q4FND7
names: Function
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.

335992:SAR11 RS02250
gene id: 335992:SAR11_RS02250
uniprot id: Q4FNH1
names: Similarity
messages: Belongs to the type II topoisomerase GyrB family.

335992:SAR11 RS01725
gene id: 335992:SAR11_RS01725
uniprot id: Q4FNS4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family.
messages: Cytoplasm
messages: Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

335992:SAR11 RS02915
gene id: 335992:SAR11_RS02915
uniprot id: Q4FN44
names: Similarity
messages: Belongs to the AlaDH/PNT family.

335992:SAR11 RS00505
gene id: 335992:SAR11_RS00505
uniprot id: Q4FPG6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b family.
messages: Binds 2 heme groups non-covalently.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

335992:SAR11 RS05635
gene id: 335992:SAR11_RS05635
uniprot id: Q4FLK7
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

335992:SAR11 RS05620
gene id: 335992:SAR11_RS05620
uniprot id: Q4FLL0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

335992:SAR11 RS06685
gene id: 335992:SAR11_RS06685
uniprot id: Q4FKZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

335992:SAR11 RS04800
gene id: 335992:SAR11_RS04800
uniprot id: Q4FM20
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

335992:SAR11 RS04845
gene id: 335992:SAR11_RS04845
uniprot id: Q4FM11
names: Similarity
messages: Belongs to the dGTPase family. Type 2 subfamily.

335992:SAR11 RS03670
gene id: 335992:SAR11_RS03670
uniprot id: Q4FMP4
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

335992:SAR11 RS01075
gene id: 335992:SAR11_RS01075
uniprot id: Q4FP52
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

335992:SAR11 RS03765
gene id: 335992:SAR11_RS03765
uniprot id: Q4FMM5
names: Similarity
messages: Belongs to the HesB/IscA family.

335992:SAR11 RS02700
gene id: 335992:SAR11_RS02700
uniprot id: Q4FN87
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

335992:SAR11 RS05560
gene id: 335992:SAR11_RS05560
uniprot id: Q4FLM2
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

335992:SAR11 RS06480
gene id: 335992:SAR11_RS06480
uniprot id: Q4FL40
names: Similarity
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.

335992:SAR11 RS01000
gene id: 335992:SAR11_RS01000
uniprot id: Q4FP67
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

335992:SAR11 RS03585
gene id: 335992:SAR11_RS03585
uniprot id: Q4FMR1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

335992:SAR11 RS02235
gene id: 335992:SAR11_RS02235
uniprot id: Q4FNH3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell inner membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

335992:SAR11 RS00020
gene id: 335992:SAR11_RS00020
uniprot id: Q4FPQ4
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

335992:SAR11 RS05470
gene id: 335992:SAR11_RS05470
uniprot id: Q4FLP0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

335992:SAR11 RS05275
gene id: 335992:SAR11_RS05275
uniprot id: Q4FLS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

335992:SAR11 RS00900
gene id: 335992:SAR11_RS00900
uniprot id: Q4FP87
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

335992:SAR11 RS02735
gene id: 335992:SAR11_RS02735
uniprot id: Q4FN80
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

335992:SAR11 RS01710
gene id: 335992:SAR11_RS01710
uniprot id: Q4FNS7
names: Function
names: Subunit
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease.

335992:SAR11 RS02165
gene id: 335992:SAR11_RS02165
uniprot id: Q4FNI7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Forms a 24-polypeptide structural core with octahedral symmetry.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

335992:SAR11 RS05615
gene id: 335992:SAR11_RS05615
uniprot id: Q4FLL1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

335992:SAR11 RS03700
gene id: 335992:SAR11_RS03700
uniprot id: Q4FMN8
names: Similarity
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.
messages: Membrane

335992:SAR11 RS05585
gene id: 335992:SAR11_RS05585
uniprot id: Q4FLL7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

335992:SAR11 RS04635
gene id: 335992:SAR11_RS04635
uniprot id: Q4FM51
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

335992:SAR11 RS03445
gene id: 335992:SAR11_RS03445
uniprot id: Q4FMT9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.

335992:SAR11 RS06835
gene id: 335992:SAR11_RS06835
uniprot id: Q4FKW9
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

335992:SAR11 RS01290
gene id: 335992:SAR11_RS01290
uniprot id: Q4FP09
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell inner membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

335992:SAR11 RS03940
gene id: 335992:SAR11_RS03940
uniprot id: Q4FMI9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
messages: Belongs to the azoreductase type 1 family.
messages: Binds 1 FMN per subunit.
messages: Homodimer.
messages: Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones.

335992:SAR11 RS05740
gene id: 335992:SAR11_RS05740
uniprot id: Q4FLJ1
names: Similarity
messages: Belongs to the CFA/CMAS family.

335992:SAR11 RS05435
gene id: 335992:SAR11_RS05435
uniprot id: Q4FLP7
names: Similarity
messages: Belongs to the UDPGP type 2 family.

335992:SAR11 RS05770
gene id: 335992:SAR11_RS05770
uniprot id: Q4FLI5
names: Similarity
messages: Belongs to the class-II DAHP synthase family.

335992:SAR11 RS01850
gene id: 335992:SAR11_RS01850
uniprot id: Q4FNP9
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

335992:SAR11 RS01410
gene id: 335992:SAR11_RS01410
uniprot id: Q4FNY5
names: Similarity
messages: Belongs to the thioredoxin family. DsbE subfamily.

335992:SAR11 RS05515
gene id: 335992:SAR11_RS05515
uniprot id: Q4FLN1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

335992:SAR11 RS02455
gene id: 335992:SAR11_RS02455
uniprot id: Q4FND2
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

335992:SAR11 RS02395
gene id: 335992:SAR11_RS02395
uniprot id: Q4FNE2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

335992:SAR11 RS05310
gene id: 335992:SAR11_RS05310
uniprot id: Q4FLS1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

335992:SAR11 RS05290
gene id: 335992:SAR11_RS05290
uniprot id: Q4FLS5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

335992:SAR11 RS02975
gene id: 335992:SAR11_RS02975
uniprot id: Q4FN33
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

335992:SAR11 RS02675
gene id: 335992:SAR11_RS02675
uniprot id: Q4FN92
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

335992:SAR11 RS04450
gene id: 335992:SAR11_RS04450
uniprot id: Q4FM88
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

335992:SAR11 RS05720
gene id: 335992:SAR11_RS05720
uniprot id: Q4FLJ5
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

335992:SAR11 RS03375
gene id: 335992:SAR11_RS03375
uniprot id: Q4FMV3
names: Similarity
messages: Belongs to the GcvT family.

335992:SAR11 RS03120
gene id: 335992:SAR11_RS03120
uniprot id: Q4FN05
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
messages: Homodimer.

335992:SAR11 RS06045
gene id: 335992:SAR11_RS06045
uniprot id: Q4FLC8
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

335992:SAR11 RS02160
gene id: 335992:SAR11_RS02160
uniprot id: Q4FNI8
names: Function
names: Subunit
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
messages: Homodimer. Part of the PDH complex, consisting of multiple copies of pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

335992:SAR11 RS01030
gene id: 335992:SAR11_RS01030
uniprot id: Q4FP61
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

335992:SAR11 RS01440
gene id: 335992:SAR11_RS01440
uniprot id: Q4FNX9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YciB family.
messages: Cell inner membrane
messages: Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.

335992:SAR11 RS06485
gene id: 335992:SAR11_RS06485
uniprot id: Q4FL39
names: Similarity
messages: Belongs to the FAD-binding monooxygenase family.

335992:SAR11 RS04160
gene id: 335992:SAR11_RS04160
uniprot id: Q4FME4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm

335992:SAR11 RS03625
gene id: 335992:SAR11_RS03625
uniprot id: Q4FMQ3
names: Similarity
messages: Belongs to the NDK family.

335992:SAR11 RS03750
gene id: 335992:SAR11_RS03750
uniprot id: Q4FMM8
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Seems to participate in the biosynthesis of the nitrogenase metalloclusters by providing the inorganic sulfur required for the Fe-S core formation.

335992:SAR11 RS00300
gene id: 335992:SAR11_RS00300
uniprot id: Q4FPL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell inner membrane
messages: Membrane

335992:SAR11 RS00305
gene id: 335992:SAR11_RS00305
uniprot id: Q4FPL8
names: Similarity
messages: Belongs to the GSP E family.

335992:SAR11 RS06870
gene id: 335992:SAR11_RS06870
uniprot id: Q4FKW2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

335992:SAR11 RS03715
gene id: 335992:SAR11_RS03715
uniprot id: Q4FMN5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

335992:SAR11 RS06550
gene id: 335992:SAR11_RS06550
uniprot id: Q4FL26
names: Similarity
messages: Belongs to the glutamate synthase family.

335992:SAR11 RS05450
gene id: 335992:SAR11_RS05450
uniprot id: Q4FLP4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

335992:SAR11 RS00265
gene id: 335992:SAR11_RS00265
uniprot id: Q4FPP4
names: Subcellular Location Annotation
messages: Cell membrane

335992:SAR11 RS03480
gene id: 335992:SAR11_RS03480
uniprot id: Q4FMT2
names: Similarity
messages: Belongs to the amidinotransferase family.

335992:SAR11 RS01845
gene id: 335992:SAR11_RS01845
uniprot id: Q4FNQ0
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

335992:SAR11 RS02275
gene id: 335992:SAR11_RS02275
uniprot id: Q4FNG6
names: Similarity
messages: Belongs to the BolA/IbaG family.

335992:SAR11 RS03485
gene id: 335992:SAR11_RS03485
uniprot id: Q4FMT1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the threonine aldolase family.
messages: Catalyzes the cleavage of L-allo-threonine and L-threonine to glycine and acetaldehyde.
messages: Homotetramer.

335992:SAR11 RS01125
gene id: 335992:SAR11_RS01125
uniprot id: Q4FP42
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein L14 (rplN).

335992:SAR11 RS05445
gene id: 335992:SAR11_RS05445
uniprot id: Q4FLP5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

335992:SAR11 RS03310
gene id: 335992:SAR11_RS03310
uniprot id: Q4FMW6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

335992:SAR11 RS01040
gene id: 335992:SAR11_RS01040
uniprot id: Q4FP59
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

335992:SAR11 RS03110
gene id: 335992:SAR11_RS03110
uniprot id: Q4FN07
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

335992:SAR11 RS06210
gene id: 335992:SAR11_RS06210
uniprot id: Q4FL97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

335992:SAR11 RS01820
gene id: 335992:SAR11_RS01820
uniprot id: Q4FNQ5
names: Similarity
messages: Belongs to the YkuD family.

335992:SAR11 RS02145
gene id: 335992:SAR11_RS02145
uniprot id: Q4FNJ0
names: Similarity
messages: Belongs to the thioesterase PaaI family.

335992:SAR11 RS00700
gene id: 335992:SAR11_RS00700
uniprot id: Q4FPC8
names: Function
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. S-2-haloalkanoic acid dehalogenase family.
messages: Catalyzes the hydrolytic dehalogenation of small (S)-2-haloalkanoic acids to yield the corresponding (R)-2-hydroxyalkanoic acids.

335992:SAR11 RS01965
gene id: 335992:SAR11_RS01965
uniprot id: Q4FNM6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

335992:SAR11 RS00500
gene id: 335992:SAR11_RS00500
uniprot id: Q4FPG7
names: Subcellular Location Annotation
messages: Membrane
messages: Mitochondrion inner membrane

335992:SAR11 RS04170
gene id: 335992:SAR11_RS04170
uniprot id: Q4FME2
names: Subcellular Location Annotation
messages: Membrane

335992:SAR11 RS03075
gene id: 335992:SAR11_RS03075
uniprot id: Q4FN13
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

335992:SAR11 RS05245
gene id: 335992:SAR11_RS05245
uniprot id: Q4FLT4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.

335992:SAR11 RS05790
gene id: 335992:SAR11_RS05790
uniprot id: Q4FLI1
names: Similarity
messages: Belongs to the PrpD family.

335992:SAR11 RS01655
gene id: 335992:SAR11_RS01655
uniprot id: Q4FNT8
names: Similarity
messages: Belongs to the PRA-PH family.

335992:SAR11 RS04325
gene id: 335992:SAR11_RS04325
uniprot id: Q4FMB1
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

335992:SAR11 RS01890
gene id: 335992:SAR11_RS01890
uniprot id: Q4FNP1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

335992:SAR11 RS03535
gene id: 335992:SAR11_RS03535
uniprot id: Q4FMS1
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

335992:SAR11 RS02960
gene id: 335992:SAR11_RS02960
uniprot id: Q4FN36
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

335992:SAR11 RS06755
gene id: 335992:SAR11_RS06755
uniprot id: Q4FKY5
names: Subcellular Location Annotation
messages: Membrane

335992:SAR11 RS01770
gene id: 335992:SAR11_RS01770
uniprot id: Q4FNR5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.

335992:SAR11 RS02570
gene id: 335992:SAR11_RS02570
uniprot id: Q4FNA9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

335992:SAR11 RS00085
gene id: 335992:SAR11_RS00085
uniprot id: Q4FPL3
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

335992:SAR11 RS03540
gene id: 335992:SAR11_RS03540
uniprot id: Q4FMS0
names: Subcellular Location Annotation
messages: Membrane

335992:SAR11 RS02670
gene id: 335992:SAR11_RS02670
uniprot id: Q4FN93
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

335992:SAR11 RS02355
gene id: 335992:SAR11_RS02355
uniprot id: Q4FNE9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

335992:SAR11 RS03550
gene id: 335992:SAR11_RS03550
uniprot id: Q4FMR8
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins.

335992:SAR11 RS01025
gene id: 335992:SAR11_RS01025
uniprot id: Q4FP62
names: Similarity
messages: Belongs to the deoxyhypusine synthase family.

335992:SAR11 RS05795
gene id: 335992:SAR11_RS05795
uniprot id: Q4FLI0
names: Function
names: Similarity
messages: Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.
messages: Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate.

335992:SAR11 RS00640
gene id: 335992:SAR11_RS00640
uniprot id: Q4FPE0
names: Similarity
messages: Belongs to the pseudomonas-type ThrB family.

335992:SAR11 RS03140
gene id: 335992:SAR11_RS03140
uniprot id: Q4FN01
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

335992:SAR11 RS04615
gene id: 335992:SAR11_RS04615
uniprot id: Q4FM55
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

335992:SAR11 RS03400
gene id: 335992:SAR11_RS03400
uniprot id: Q4FMU8
names: Similarity
messages: Belongs to the CFA/CMAS family.

335992:SAR11 RS04225
gene id: 335992:SAR11_RS04225
uniprot id: Q4FMD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Membrane

335992:SAR11 RS04570
gene id: 335992:SAR11_RS04570
uniprot id: Q4FM64
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).

335992:SAR11 RS05995
gene id: 335992:SAR11_RS05995
uniprot id: Q4FLD8
names: Caution
names: Function
names: Similarity
messages: Belongs to the Dus family. DusA subfamily.
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

335992:SAR11 RS06825
gene id: 335992:SAR11_RS06825
uniprot id: Q4FKX1
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.

335992:SAR11 RS04875
gene id: 335992:SAR11_RS04875
uniprot id: Q4FM05
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell inner membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

335992:SAR11 RS02210
gene id: 335992:SAR11_RS02210
uniprot id: Q4FNH8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-3 family.
messages: Cytoplasm
messages: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
messages: Monomer.

335992:SAR11 RS05400
gene id: 335992:SAR11_RS05400
uniprot id: Q4FLQ4
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

335992:SAR11 RS03270
gene id: 335992:SAR11_RS03270
uniprot id: Q4FMX4
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain.

335992:SAR11 RS05760
gene id: 335992:SAR11_RS05760
uniprot id: Q4FLI7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

335992:SAR11 RS05410
gene id: 335992:SAR11_RS05410
uniprot id: Q4FLQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell inner membrane
messages: Probably interacts with PlsX.

335992:SAR11 RS04605
gene id: 335992:SAR11_RS04605
uniprot id: Q4FM57
names: Function
names: Similarity
messages: Belongs to the LpxB family.
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

335992:SAR11 RS00510
gene id: 335992:SAR11_RS00510
uniprot id: Q4FPG5
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The Rieske protein is a high potential 2Fe-2S protein.
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

335992:SAR11 RS00685
gene id: 335992:SAR11_RS00685
uniprot id: Q4FPD1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

335992:SAR11 RS03165
gene id: 335992:SAR11_RS03165
uniprot id: Q4FMZ6
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

335992:SAR11 RS00750
gene id: 335992:SAR11_RS00750
uniprot id: Q4FPB8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Cell inner membrane
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

335992:SAR11 RS05815
gene id: 335992:SAR11_RS05815
uniprot id: Q4FLH6
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

335992:SAR11 RS04550
gene id: 335992:SAR11_RS04550
uniprot id: Q4FM68
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

335992:SAR11 RS01160
gene id: 335992:SAR11_RS01160
uniprot id: Q4FP35
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase delta chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

335992:SAR11 RS05755
gene id: 335992:SAR11_RS05755
uniprot id: Q4FLI8
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

335992:SAR11 RS05370
gene id: 335992:SAR11_RS05370
uniprot id: Q4FLR0
names: Function
names: Similarity
messages: Belongs to the TrhO family.
messages: Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.

335992:SAR11 RS00065
gene id: 335992:SAR11_RS00065
uniprot id: Q4FPM3
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

335992:SAR11 RS03135
gene id: 335992:SAR11_RS03135
uniprot id: Q4FN02
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

335992:SAR11 RS01180
gene id: 335992:SAR11_RS01180
uniprot id: Q4FP31
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.
messages: E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).
messages: Homodimer. Part of the 2-oxoglutarate dehydrogenase (OGDH) complex composed of E1 (2-oxoglutarate dehydrogenase), E2 (dihydrolipoamide succinyltransferase) and E3 (dihydrolipoamide dehydrogenase); the complex contains multiple copies of the three enzymatic components (E1, E2 and E3).

335992:SAR11 RS04670
gene id: 335992:SAR11_RS04670
uniprot id: Q4FM43
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

335992:SAR11 RS00845
gene id: 335992:SAR11_RS00845
uniprot id: Q4FP98
names: Similarity
messages: Belongs to the peptidase U62 family.

335992:SAR11 RS00745
gene id: 335992:SAR11_RS00745
uniprot id: Q4FPB9
names: Subcellular Location Annotation
messages: Membrane

335992:SAR11 RS01055
gene id: 335992:SAR11_RS01055
uniprot id: Q4FP56
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrkH potassium transport family.
messages: Cell inner membrane
messages: Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA.
messages: Membrane

335992:SAR11 RS03795
gene id: 335992:SAR11_RS03795
uniprot id: Q4FML8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

335992:SAR11 RS02220
gene id: 335992:SAR11_RS02220
uniprot id: Q4FNH6
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

335992:SAR11 RS05555
gene id: 335992:SAR11_RS05555
uniprot id: Q4FLM3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity).

335992:SAR11 RS06590
gene id: 335992:SAR11_RS06590
uniprot id: Q4FL18
names: Function
names: Similarity
messages: Belongs to the glutamine synthetase family.
messages: Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia.

335992:SAR11 RS00130
gene id: 335992:SAR11_RS00130
uniprot id: Q4FPK4
names: Subcellular Location Annotation
messages: Membrane

335992:SAR11 RS01330
gene id: 335992:SAR11_RS01330
uniprot id: Q4FP01
names: Similarity
messages: Belongs to the ABC transporter superfamily.

335992:SAR11 RS01255
gene id: 335992:SAR11_RS01255
uniprot id: Q4FP16
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

335992:SAR11 RS01500
gene id: 335992:SAR11_RS01500
uniprot id: Q4FNW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell inner membrane
messages: Membrane

335992:SAR11 RS02985
gene id: 335992:SAR11_RS02985
uniprot id: Q4FN31
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

335992:SAR11 RS03800
gene id: 335992:SAR11_RS03800
uniprot id: Q4FML7
names: Function
names: Similarity
messages: Belongs to the MoaB/Mog family.
messages: May be involved in the biosynthesis of molybdopterin.

335992:SAR11 RS04240
gene id: 335992:SAR11_RS04240
uniprot id: Q4FMC8
names: Similarity
messages: Belongs to the TPP enzyme family.

335992:SAR11 RS06380
gene id: 335992:SAR11_RS06380
uniprot id: Q4FL60
names: Subcellular Location Annotation
messages: Cytoplasm

335992:SAR11 RS00430
gene id: 335992:SAR11_RS00430
uniprot id: Q4FPI1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

335992:SAR11 RS03995
gene id: 335992:SAR11_RS03995
uniprot id: Q4FMH8
names: Similarity
messages: Belongs to the intimin/invasin family.

335992:SAR11 RS04805
gene id: 335992:SAR11_RS04805
uniprot id: Q4FM19
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.

335992:SAR11 RS02715
gene id: 335992:SAR11_RS02715
uniprot id: Q4FN84
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

335992:SAR11 RS01925
gene id: 335992:SAR11_RS01925
uniprot id: Q4FNN4
names: Similarity
messages: Belongs to the PhoH family.

335992:SAR11 RS00690
gene id: 335992:SAR11_RS00690
uniprot id: Q4FPD0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Binds a copper A center.
messages: Cell membrane
messages: Membrane
messages: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).

335992:SAR11 RS01670
gene id: 335992:SAR11_RS01670
uniprot id: Q4FNT5
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

335992:SAR11 RS05125
gene id: 335992:SAR11_RS05125
uniprot id: Q4FLV8
names: Subcellular Location Annotation
messages: Membrane

335992:SAR11 RS00800
gene id: 335992:SAR11_RS00800
uniprot id: Q4FPA8
names: Function
names: Similarity
messages: Belongs to the ribF family.
messages: Catalyzes the phosphorylation of riboflavin to FMN followed by the adenylation of FMN to FAD.

335992:SAR11 RS01365
gene id: 335992:SAR11_RS01365
uniprot id: Q4FNZ4
names: Subcellular Location Annotation
messages: Membrane

335992:SAR11 RS03965
gene id: 335992:SAR11_RS03965
uniprot id: Q4FMI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

335992:SAR11 RS05295
gene id: 335992:SAR11_RS05295
uniprot id: Q4FLS4
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

335992:SAR11 RS02605
gene id: 335992:SAR11_RS02605
uniprot id: Q4FNA2
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
messages: O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.

335992:SAR11 RS00790
gene id: 335992:SAR11_RS00790
uniprot id: Q4FPB0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell inner membrane
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

335992:SAR11 RS00075
gene id: 335992:SAR11_RS00075
uniprot id: Q4FPM1
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

335992:SAR11 RS06065
gene id: 335992:SAR11_RS06065
uniprot id: Q4FLC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell inner membrane
messages: Cell membrane

335992:SAR11 RS03300
gene id: 335992:SAR11_RS03300
uniprot id: Q4FMW8
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

335992:SAR11 RS02955
gene id: 335992:SAR11_RS02955
uniprot id: Q4FN37
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

335992:SAR11 RS00515
gene id: 335992:SAR11_RS00515
uniprot id: Q4FPG4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.

335992:SAR11 RS01195
gene id: 335992:SAR11_RS01195
uniprot id: Q4FP28
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 3 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

335992:SAR11 RS01860
gene id: 335992:SAR11_RS01860
uniprot id: Q4FNP7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

335992:SAR11 RS05365
gene id: 335992:SAR11_RS05365
uniprot id: Q4FLR1
names: Function
messages: Multidrug efflux pump.

335992:SAR11 RS01045
gene id: 335992:SAR11_RS01045
uniprot id: Q4FP58
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane

335992:SAR11 RS01405
gene id: 335992:SAR11_RS01405
uniprot id: Q4FNY6
names: Function
names: Similarity
messages: Belongs to the CcmH/CycL/Ccl2/NrfF family.
messages: Possible subunit of a heme lyase.

335992:SAR11 RS04085
gene id: 335992:SAR11_RS04085
uniprot id: Q4FMG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

335992:SAR11 RS04415
gene id: 335992:SAR11_RS04415
uniprot id: Q4FM93
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

335992:SAR11 RS05380
gene id: 335992:SAR11_RS05380
uniprot id: Q4FLQ8
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

335992:SAR11 RS00335
gene id: 335992:SAR11_RS00335
uniprot id: Q4FPJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Plays an essential role in type IV pili and type II pseudopili formation by proteolytically removing the leader sequence from substrate proteins and subsequently monomethylating the alpha-amino group of the newly exposed N-terminal phenylalanine.

335992:SAR11 RS04835
gene id: 335992:SAR11_RS04835
uniprot id: Q4FM13
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

335992:SAR11 RS02480
gene id: 335992:SAR11_RS02480
uniprot id: Q4FNC7
names: Function
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).

335992:SAR11 RS02950
gene id: 335992:SAR11_RS02950
uniprot id: Q4FN38
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

335992:SAR11 RS04035
gene id: 335992:SAR11_RS04035
uniprot id: Q4FMH0
names: Cofactor
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.

335992:SAR11 RS05315
gene id: 335992:SAR11_RS05315
uniprot id: Q4FLS0
names: Similarity
messages: Belongs to the virb1 family.

335992:SAR11 RS06665
gene id: 335992:SAR11_RS06665
uniprot id: Q4FL03
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

335992:SAR11 RS04075
gene id: 335992:SAR11_RS04075
uniprot id: Q4FMG2
names: Similarity
messages: Belongs to the AlaDH/PNT family.

335992:SAR11 RS04475
gene id: 335992:SAR11_RS04475
uniprot id: Q4FM83
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

335992:SAR11 RS04230
gene id: 335992:SAR11_RS04230
uniprot id: Q4FMD0
names: Similarity
messages: Belongs to the UxaA family.

335992:SAR11 RS03025
gene id: 335992:SAR11_RS03025
uniprot id: Q4FN23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

335992:SAR11 RS05335
gene id: 335992:SAR11_RS05335
uniprot id: Q4FLR7
names: Similarity
messages: Belongs to the GcvT family.

335992:SAR11 RS06850
gene id: 335992:SAR11_RS06850
uniprot id: Q4FKW6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. MrdB/RodA subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell wall elongation.

335992:SAR11 RS05475
gene id: 335992:SAR11_RS05475
uniprot id: Q4FLN9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

335992:SAR11 RS03675
gene id: 335992:SAR11_RS03675
uniprot id: Q4FMP3
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

335992:SAR11 RS05735
gene id: 335992:SAR11_RS05735
uniprot id: Q4FLJ2
names: Similarity
messages: Belongs to the glutaredoxin family. Monothiol subfamily.

335992:SAR11 RS03020
gene id: 335992:SAR11_RS03020
uniprot id: Q4FN24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

335992:SAR11 RS05640
gene id: 335992:SAR11_RS05640
uniprot id: Q4FLK6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell inner membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

335992:SAR11 RS03650
gene id: 335992:SAR11_RS03650
uniprot id: Q4FMP8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.

335992:SAR11 RS04565
gene id: 335992:SAR11_RS04565
uniprot id: Q4FM65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

335992:SAR11 RS01090
gene id: 335992:SAR11_RS01090
uniprot id: Q4FP49
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Monomer.
messages: Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.

335992:SAR11 RS01220
gene id: 335992:SAR11_RS01220
uniprot id: Q4FP23
names: Function
names: Subunit
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD. The complex can form homotrimers.

335992:SAR11 RS02580
gene id: 335992:SAR11_RS02580
uniprot id: Q4FNA7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the malate synthase family. GlcB subfamily.
messages: Cytoplasm
messages: Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

335992:SAR11 RS02590
gene id: 335992:SAR11_RS02590
uniprot id: Q4FNA5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell inner membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

335992:SAR11 RS05905
gene id: 335992:SAR11_RS05905
uniprot id: Q4FLF7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

335992:SAR11 RS02965
gene id: 335992:SAR11_RS02965
uniprot id: Q4FN35
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).

335992:SAR11 RS01720
gene id: 335992:SAR11_RS01720
uniprot id: Q4FNS5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).

335992:SAR11 RS04220
gene id: 335992:SAR11_RS04220
uniprot id: Q4FMD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

335992:SAR11 RS04700
gene id: 335992:SAR11_RS04700
uniprot id: Q4FM37
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

335992:SAR11 RS02895
gene id: 335992:SAR11_RS02895
uniprot id: Q4FN47
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. Fucose synthase subfamily.
messages: Catalyzes the two-step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

335992:SAR11 RS01260
gene id: 335992:SAR11_RS01260
uniprot id: Q4FP15
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

335992:SAR11 RS04025
gene id: 335992:SAR11_RS04025
uniprot id: Q4FMH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

335992:SAR11 RS00650
gene id: 335992:SAR11_RS00650
uniprot id: Q4FPD8
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family. Prx5 subfamily.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

335992:SAR11 RS03185
gene id: 335992:SAR11_RS03185
uniprot id: Q4FMZ2
names: Similarity
messages: Belongs to the adrenodoxin/putidaredoxin family.

335992:SAR11 RS04610
gene id: 335992:SAR11_RS04610
uniprot id: Q4FM56
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Monomer.

335992:SAR11 RS01535
gene id: 335992:SAR11_RS01535
uniprot id: Q4FNW1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

335992:SAR11 RS04850
gene id: 335992:SAR11_RS04850
uniprot id: Q4FM10
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

335992:SAR11 RS01950
gene id: 335992:SAR11_RS01950
uniprot id: Q4FNM9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

335992:SAR11 RS04725
gene id: 335992:SAR11_RS04725
uniprot id: Q4FM32
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG).

335992:SAR11 RS03000
gene id: 335992:SAR11_RS03000
uniprot id: Q4FN28
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

335992:SAR11 RS00490
gene id: 335992:SAR11_RS00490
uniprot id: Q4FPG9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

335992:SAR11 RS00660
gene id: 335992:SAR11_RS00660
uniprot id: Q4FPD6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF1 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

335992:SAR11 RS00095
gene id: 335992:SAR11_RS00095
uniprot id: Q4FPL1
names: Function
names: Similarity
messages: Belongs to the LpxC family.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

335992:SAR11 RS05800
gene id: 335992:SAR11_RS05800
uniprot id: Q4FLH9
names: Similarity
messages: Belongs to the citrate synthase family.

335992:SAR11 RS03345
gene id: 335992:SAR11_RS03345
uniprot id: Q4FMV9
names: Similarity
messages: Belongs to the D-glutamate cyclase family.

335992:SAR11 RS01215
gene id: 335992:SAR11_RS01215
uniprot id: Q4FP24
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).

335992:SAR11 RS04820
gene id: 335992:SAR11_RS04820
uniprot id: Q4FM16
names: Function
messages: Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes.

335992:SAR11 RS05595
gene id: 335992:SAR11_RS05595
uniprot id: Q4FLL5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

335992:SAR11 RS00695
gene id: 335992:SAR11_RS00695
uniprot id: Q4FPC9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

335992:SAR11 RS01060
gene id: 335992:SAR11_RS01060
uniprot id: Q4FP55
names: Subcellular Location Annotation
messages: Membrane

335992:SAR11 RS00080
gene id: 335992:SAR11_RS00080
uniprot id: Q4FPM0
names: Similarity
messages: Belongs to the peptidase M24B family.

335992:SAR11 RS00770
gene id: 335992:SAR11_RS00770
uniprot id: Q4FPB4
names: Similarity
messages: Belongs to the GARS family.

335992:SAR11 RS01745
gene id: 335992:SAR11_RS01745
uniprot id: Q4FNS0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HemJ family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Catalyzes the oxidation of protoporphyrinogen IX to protoporphyrin IX.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

335992:SAR11 RS03740
gene id: 335992:SAR11_RS03740
uniprot id: Q4FMN0
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

335992:SAR11 RS05415
gene id: 335992:SAR11_RS05415
uniprot id: Q4FLQ1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

335992:SAR11 RS02365
gene id: 335992:SAR11_RS02365
uniprot id: Q4FNE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Membrane

335992:SAR11 RS04770
gene id: 335992:SAR11_RS04770
uniprot id: Q4FM24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

335992:SAR11 RS01325
gene id: 335992:SAR11_RS01325
uniprot id: Q4FP02
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial solute-binding protein 7 family.
messages: Homodimer.
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: Periplasm

335992:SAR11 RS04695
gene id: 335992:SAR11_RS04695
uniprot id: Q4FM38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

335992:SAR11 RS01430
gene id: 335992:SAR11_RS01430
uniprot id: Q4FNY1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmC/CycZ/HelC family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

335992:SAR11 RS01375
gene id: 335992:SAR11_RS01375
uniprot id: Q4FNZ2
names: Cofactor
names: Function
messages: Binds 2 [4Fe-4S] clusters.
messages: Component of a complex that catalyzes the oxidation of glycolate to glyoxylate.

335992:SAR11 RS06170
gene id: 335992:SAR11_RS06170
uniprot id: Q4FLA5
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Multidrug efflux pump.

335992:SAR11 RS03045
gene id: 335992:SAR11_RS03045
uniprot id: Q4FN19
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpoB family.
messages: Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division.
messages: Periplasm

335992:SAR11 RS06220
gene id: 335992:SAR11_RS06220
uniprot id: Q4FL94
names: Cofactor
messages: Can also use Mn(2+) ion.

335992:SAR11 RS00030
gene id: 335992:SAR11_RS00030
uniprot id: Q4FPN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Periplasm

335992:SAR11 RS05675
gene id: 335992:SAR11_RS05675
uniprot id: Q4FLK3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

335992:SAR11 RS01995
gene id: 335992:SAR11_RS01995
uniprot id: Q4FNM0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes.
messages: Belongs to the Fur family.
messages: Cytoplasm
messages: Homodimer.

335992:SAR11 RS04525
gene id: 335992:SAR11_RS04525
uniprot id: Q4FM73
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 2 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Cytoplasm
messages: Homodimer.

335992:SAR11 RS06600
gene id: 335992:SAR11_RS06600
uniprot id: Q4FL16
names: Similarity
messages: Belongs to the DNA photolyase family.

335992:SAR11 RS00595
gene id: 335992:SAR11_RS00595
uniprot id: Q4FPE9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase A chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.

335992:SAR11 RS00985
gene id: 335992:SAR11_RS00985
uniprot id: Q4FP70
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

335992:SAR11 RS03825
gene id: 335992:SAR11_RS03825
uniprot id: Q4FML2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MsrP family.
messages: Binds 1 Mo-molybdopterin (Mo-MPT) cofactor per subunit.
messages: Heterodimer of a catalytic subunit (MsrP) and a heme-binding subunit (MsrQ).
messages: Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide.
messages: Periplasm

335992:SAR11 RS05510
gene id: 335992:SAR11_RS05510
uniprot id: Q4FLN2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

335992:SAR11 RS02040
gene id: 335992:SAR11_RS02040
uniprot id: Q4FNL1
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).

335992:SAR11 RS00380
gene id: 335992:SAR11_RS00380
uniprot id: Q4FPJ1
names: Similarity
messages: Belongs to the GSP E family.

335992:SAR11 RS05605
gene id: 335992:SAR11_RS05605
uniprot id: Q4FLL3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

335992:SAR11 RS01930
gene id: 335992:SAR11_RS01930
uniprot id: Q4FNN3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

335992:SAR11 RS04465
gene id: 335992:SAR11_RS04465
uniprot id: Q4FM85
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the complex I 75 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

335992:SAR11 RS02620
gene id: 335992:SAR11_RS02620
uniprot id: Q4FN99
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

335992:SAR11 RS00880
gene id: 335992:SAR11_RS00880
uniprot id: Q4FP91
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.

335992:SAR11 RS00145
gene id: 335992:SAR11_RS00145
uniprot id: Q4FPK1
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

335992:SAR11 RS00135
gene id: 335992:SAR11_RS00135
uniprot id: Q4FPK3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

335992:SAR11 RS05220
gene id: 335992:SAR11_RS05220
uniprot id: Q4FLT9
names: Similarity
messages: Belongs to the DMRL synthase family.

335992:SAR11 RS05500
gene id: 335992:SAR11_RS05500
uniprot id: Q4FLN4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

335992:SAR11 RS03155
gene id: 335992:SAR11_RS03155
uniprot id: Q4FMZ8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

335992:SAR11 RS01050
gene id: 335992:SAR11_RS01050
uniprot id: Q4FP57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

335992:SAR11 RS05730
gene id: 335992:SAR11_RS05730
uniprot id: Q4FLJ3
names: Similarity
messages: Belongs to the BolA/IbaG family.

335992:SAR11 RS02230
gene id: 335992:SAR11_RS02230
uniprot id: Q4FNH4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

335992:SAR11 RS02045
gene id: 335992:SAR11_RS02045
uniprot id: Q4FNL0
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Monomer.

335992:SAR11 RS04990
gene id: 335992:SAR11_RS04990
uniprot id: Q4FLY3
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

335992:SAR11 RS02330
gene id: 335992:SAR11_RS02330
uniprot id: Q4FNF4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family.
messages: Cytoplasm
messages: Homotrimer.

335992:SAR11 RS02900
gene id: 335992:SAR11_RS02900
uniprot id: Q4FN46
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

335992:SAR11 RS05170
gene id: 335992:SAR11_RS05170
uniprot id: Q4FLU9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

335992:SAR11 RS02575
gene id: 335992:SAR11_RS02575
uniprot id: Q4FNA8
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

335992:SAR11 RS05820
gene id: 335992:SAR11_RS05820
uniprot id: Q4FLH5
names: Similarity
messages: Belongs to the phosphohexose mutase family.

335992:SAR11 RS01230
gene id: 335992:SAR11_RS01230
uniprot id: Q4FP21
names: Activity Regulation
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the GcvT family. DmdA subfamily.
messages: DMSP is used as an intracellular osmolyte, predator deterrent and antioxidant.
messages: Homodimer.
messages: Major contributor to the demethylation of dimethylsulfonioproprionate (DMSP). Demethylates DMSP to methyl-mercaptopropionate (MMPA).
messages: Non-competitively inhibited by MMPA, weakly inhibited by substrate analogs dimethylsulfoniobutanoate and dimethylsulfoniopentanoate. It is used as an intracellular osmolyte.

335992:SAR11 RS04445
gene id: 335992:SAR11_RS04445
uniprot id: Q4FM89
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 30 kDa subunit family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

335992:SAR11 RS01080
gene id: 335992:SAR11_RS01080
uniprot id: Q4FP51
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

335992:SAR11 RS05010
gene id: 335992:SAR11_RS05010
uniprot id: Q4FLX9
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.

335992:SAR11 RS01665
gene id: 335992:SAR11_RS01665
uniprot id: Q4FNT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

335992:SAR11 RS06470
gene id: 335992:SAR11_RS06470
uniprot id: Q4FL42
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

335992:SAR11 RS02540
gene id: 335992:SAR11_RS02540
uniprot id: Q4FNB5
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

335992:SAR11 RS05580
gene id: 335992:SAR11_RS05580
uniprot id: Q4FLL8
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: Methylated by PrmB.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

335992:SAR11 RS04115
gene id: 335992:SAR11_RS04115
uniprot id: Q4FMF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Membrane

335992:SAR11 RS00215
gene id: 335992:SAR11_RS00215
uniprot id: Q4FPQ8
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

335992:SAR11 RS01885
gene id: 335992:SAR11_RS01885
uniprot id: Q4FNP2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell inner membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

335992:SAR11 RS04885
gene id: 335992:SAR11_RS04885
uniprot id: Q4FM03
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

335992:SAR11 RS04045
gene id: 335992:SAR11_RS04045
uniprot id: Q4FMG8
names: Similarity
messages: Belongs to the peptidase S33 family.

335992:SAR11 RS05055
gene id: 335992:SAR11_RS05055
uniprot id: Q4FLX1
names: Similarity
messages: Belongs to the RecJ family.

335992:SAR11 RS04345
gene id: 335992:SAR11_RS04345
uniprot id: Q4FMA7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

335992:SAR11 RS00160
gene id: 335992:SAR11_RS00160
uniprot id: Q4FPN5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

335992:SAR11 RS00555
gene id: 335992:SAR11_RS00555
uniprot id: Q4FPF7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

335992:SAR11 RS01105
gene id: 335992:SAR11_RS01105
uniprot id: Q4FP46
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

335992:SAR11 RS03590
gene id: 335992:SAR11_RS03590
uniprot id: Q4FMR0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

335992:SAR11 RS02450
gene id: 335992:SAR11_RS02450
uniprot id: Q4FND3
names: Similarity
messages: Belongs to the thioredoxin family.

335992:SAR11 RS01340
gene id: 335992:SAR11_RS01340
uniprot id: Q4FNZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

335992:SAR11 RS01265
gene id: 335992:SAR11_RS01265
uniprot id: Q4FP14
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

335992:SAR11 RS01250
gene id: 335992:SAR11_RS01250
uniprot id: Q4FP17
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

335992:SAR11 RS06630
gene id: 335992:SAR11_RS06630
uniprot id: Q4FL10
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.

335992:SAR11 RS05270
gene id: 335992:SAR11_RS05270
uniprot id: Q4FLS9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

335992:SAR11 RS02870
gene id: 335992:SAR11_RS02870
uniprot id: Q4FN52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the O-antigen polymerase family.
messages: Membrane

335992:SAR11 RS03880
gene id: 335992:SAR11_RS03880
uniprot id: Q4FMK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

335992:SAR11 RS02625
gene id: 335992:SAR11_RS02625
uniprot id: Q4FN98
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

335992:SAR11 RS05485
gene id: 335992:SAR11_RS05485
uniprot id: Q4FLN7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell inner membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

335992:SAR11 RS04715
gene id: 335992:SAR11_RS04715
uniprot id: Q4FM34
names: Similarity
messages: Belongs to the ribosome association toxin RatA family.

335992:SAR11 RS06585
gene id: 335992:SAR11_RS06585
uniprot id: Q4FL19
names: Similarity
messages: Belongs to the glutamate synthase family.

335992:SAR11 RS00470
gene id: 335992:SAR11_RS00470
uniprot id: Q4FPH3
names: Subcellular Location Annotation
messages: Mitochondrion

335992:SAR11 RS01840
gene id: 335992:SAR11_RS01840
uniprot id: Q4FNQ1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

335992:SAR11 RS01960
gene id: 335992:SAR11_RS01960
uniprot id: Q4FNM7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

335992:SAR11 RS03115
gene id: 335992:SAR11_RS03115
uniprot id: Q4FN06
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

335992:SAR11 RS05705
gene id: 335992:SAR11_RS05705
uniprot id: Q4FLJ8
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

335992:SAR11 RS00480
gene id: 335992:SAR11_RS00480
uniprot id: Q4FPH1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

335992:SAR11 RS03260
gene id: 335992:SAR11_RS03260
uniprot id: Q4FMX6
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

335992:SAR11 RS01395
gene id: 335992:SAR11_RS01395
uniprot id: Q4FNY8
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

335992:SAR11 RS00125
gene id: 335992:SAR11_RS00125
uniprot id: Q4FPK5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell inner membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).

335992:SAR11 RS00435
gene id: 335992:SAR11_RS00435
uniprot id: Q4FPI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

335992:SAR11 RS01020
gene id: 335992:SAR11_RS01020
uniprot id: Q4FP63
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

335992:SAR11 RS02925
gene id: 335992:SAR11_RS02925
uniprot id: Q4FN42
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PNT beta subunit family.
messages: Cell inner membrane
messages: Membrane
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

335992:SAR11 RS00550
gene id: 335992:SAR11_RS00550
uniprot id: Q4FPF8
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.

335992:SAR11 RS03285
gene id: 335992:SAR11_RS03285
uniprot id: Q4FMX1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
messages: Cytoplasm
messages: Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.

335992:SAR11 RS01315
gene id: 335992:SAR11_RS01315
uniprot id: Q4FP04
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

335992:SAR11 RS01110
gene id: 335992:SAR11_RS01110
uniprot id: Q4FP45
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

335992:SAR11 RS05890
gene id: 335992:SAR11_RS05890
uniprot id: Q4FLG1
names: Cofactor
messages: Binds 1 zinc ion per subunit.

335992:SAR11 RS05530
gene id: 335992:SAR11_RS05530
uniprot id: Q4FLM8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

335992:SAR11 RS06280
gene id: 335992:SAR11_RS06280
uniprot id: Q4FL81
names: Similarity
messages: Belongs to the GcvT family.

335992:SAR11 RS06080
gene id: 335992:SAR11_RS06080
uniprot id: Q4FLC1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

335992:SAR11 RS02380
gene id: 335992:SAR11_RS02380
uniprot id: Q4FNE5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Catalyzes the deamination of dCTP to dUTP.
messages: Homotrimer.

335992:SAR11 RS06435
gene id: 335992:SAR11_RS06435
uniprot id: Q4FL49
names: Similarity
messages: Belongs to the formate--tetrahydrofolate ligase family.

335992:SAR11 RS06725
gene id: 335992:SAR11_RS06725
uniprot id: Q4FKZ1
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

335992:SAR11 RS00090
gene id: 335992:SAR11_RS00090
uniprot id: Q4FPL2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamD family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

335992:SAR11 RS04245
gene id: 335992:SAR11_RS04245
uniprot id: Q4FMC7
names: Similarity
messages: Belongs to the FAD-binding monooxygenase family.

335992:SAR11 RS02585
gene id: 335992:SAR11_RS02585
uniprot id: Q4FNA6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

335992:SAR11 RS05650
gene id: 335992:SAR11_RS05650
uniprot id: Q4FLK5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

335992:SAR11 RS00440
gene id: 335992:SAR11_RS00440
uniprot id: Q4FPH9
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

335992:SAR11 RS01210
gene id: 335992:SAR11_RS01210
uniprot id: Q4FP25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Cell inner membrane
messages: Membrane

335992:SAR11 RS01170
gene id: 335992:SAR11_RS01170
uniprot id: Q4FP33
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

335992:SAR11 RS01915
gene id: 335992:SAR11_RS01915
uniprot id: Q4FNN6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes.
messages: Belongs to the Fur family.
messages: Cytoplasm
messages: Homodimer.

335992:SAR11 RS01150
gene id: 335992:SAR11_RS01150
uniprot id: Q4FP37
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

335992:SAR11 RS04915
gene id: 335992:SAR11_RS04915
uniprot id: Q4FLZ7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

335992:SAR11 RS01145
gene id: 335992:SAR11_RS01145
uniprot id: Q4FP38
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

335992:SAR11 RS00530
gene id: 335992:SAR11_RS00530
uniprot id: Q4FPG1
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

335992:SAR11 RS05600
gene id: 335992:SAR11_RS05600
uniprot id: Q4FLL4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

335992:SAR11 RS04890
gene id: 335992:SAR11_RS04890
uniprot id: Q4FM02
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.

335992:SAR11 RS04435
gene id: 335992:SAR11_RS04435
uniprot id: Q4FM91
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

335992:SAR11 RS06075
gene id: 335992:SAR11_RS06075
uniprot id: Q4FLC2
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

335992:SAR11 RS01275
gene id: 335992:SAR11_RS01275
uniprot id: Q4FP12
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

335992:SAR11 RS00415
gene id: 335992:SAR11_RS00415
uniprot id: Q4FPI4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

335992:SAR11 RS00465
gene id: 335992:SAR11_RS00465
uniprot id: Q4FPH4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell inner membrane

335992:SAR11 RS03060
gene id: 335992:SAR11_RS03060
uniprot id: Q4FN16
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

335992:SAR11 RS03170
gene id: 335992:SAR11_RS03170
uniprot id: Q4FMZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

335992:SAR11 RS06785
gene id: 335992:SAR11_RS06785
uniprot id: Q4FKX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

335992:SAR11 RS04895
gene id: 335992:SAR11_RS04895
uniprot id: Q4FM01
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YajC family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the SecDF-YidC-YajC translocase complex. The SecDF-YidC-YajC translocase forms a supercomplex with SecYEG, called the holo-translocon (HTL).
messages: The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions.

335992:SAR11 RS04510
gene id: 335992:SAR11_RS04510
uniprot id: Q4FM76
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

335992:SAR11 RS06535
gene id: 335992:SAR11_RS06535
uniprot id: Q4FL29
names: Similarity
messages: Belongs to the glutamine synthetase family.

335992:SAR11 RS05535
gene id: 335992:SAR11_RS05535
uniprot id: Q4FLM7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

335992:SAR11 RS02565
gene id: 335992:SAR11_RS02565
uniprot id: Q4FNB0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

335992:SAR11 RS02070
gene id: 335992:SAR11_RS02070
uniprot id: Q4FNK5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

335992:SAR11 RS04310
gene id: 335992:SAR11_RS04310
uniprot id: Q4FMB4
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

335992:SAR11 RS03600
gene id: 335992:SAR11_RS03600
uniprot id: Q4FMQ8
names: Similarity
messages: Belongs to the PpiC/parvulin rotamase family.

335992:SAR11 RS05155
gene id: 335992:SAR11_RS05155
uniprot id: Q4FLV2
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

335992:SAR11 RS05540
gene id: 335992:SAR11_RS05540
uniprot id: Q4FLM6
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

335992:SAR11 RS02345
gene id: 335992:SAR11_RS02345
uniprot id: Q4FNF1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell inner membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

335992:SAR11 RS05205
gene id: 335992:SAR11_RS05205
uniprot id: Q4FLU2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-insensitive subfamily.
messages: Cell inner membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force.

335992:SAR11 RS01540
gene id: 335992:SAR11_RS01540
uniprot id: Q4FNW0
names: Similarity
messages: Belongs to the YggT family.

335992:SAR11 RS04355
gene id: 335992:SAR11_RS04355
uniprot id: Q4FMA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

335992:SAR11 RS06770
gene id: 335992:SAR11_RS06770
uniprot id: Q4FKY2
names: Similarity
messages: Belongs to the pyrroline-5-carboxylate reductase family.

335992:SAR11 RS02680
gene id: 335992:SAR11_RS02680
uniprot id: Q4FN91
names: Similarity
messages: Belongs to the TPP enzyme family.

335992:SAR11 RS06750
gene id: 335992:SAR11_RS06750
uniprot id: Q4FKY6
names: Subcellular Location Annotation
messages: Membrane

335992:SAR11 RS02420
gene id: 335992:SAR11_RS02420
uniprot id: Q4FND9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

335992:SAR11 RS02515
gene id: 335992:SAR11_RS02515
uniprot id: Q4FNC0
names: Similarity
messages: Belongs to the SIS family. GutQ/KpsF subfamily.

335992:SAR11 RS03150
gene id: 335992:SAR11_RS03150
uniprot id: Q4FMZ9
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

335992:SAR11 RS03785
gene id: 335992:SAR11_RS03785
uniprot id: Q4FMM0
names: Cofactor
messages: Binds 1 zinc ion per subunit.

335992:SAR11 RS04455
gene id: 335992:SAR11_RS04455
uniprot id: Q4FM87
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

335992:SAR11 RS04555
gene id: 335992:SAR11_RS04555
uniprot id: Q4FM67
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

335992:SAR11 RS00290
gene id: 335992:SAR11_RS00290
uniprot id: Q4FPN9
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

335992:SAR11 RS02615
gene id: 335992:SAR11_RS02615
uniprot id: Q4FNA0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

335992:SAR11 RS05040
gene id: 335992:SAR11_RS05040
uniprot id: Q4FLX4
names: Function
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.

335992:SAR11 RS00850
gene id: 335992:SAR11_RS00850
uniprot id: Q4FP97
names: Similarity
messages: Belongs to the peptidase U62 family.

335992:SAR11 RS01780
gene id: 335992:SAR11_RS01780
uniprot id: Q4FNR3
names: Function
names: Similarity
messages: Belongs to the ParB family.
messages: Involved in chromosome partition. Localize to both poles of the predivisional cell following completion of DNA replication. Binds to the DNA origin of replication.

335992:SAR11 RS05710
gene id: 335992:SAR11_RS05710
uniprot id: Q4FLJ7
names: Similarity
messages: Belongs to the SAICAR synthetase family.

335992:SAR11 RS06560
gene id: 335992:SAR11_RS06560
uniprot id: Q4FL24
names: Subcellular Location Annotation
messages: Membrane

335992:SAR11 RS01730
gene id: 335992:SAR11_RS01730
uniprot id: Q4FNS3
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.

335992:SAR11 RS00635
gene id: 335992:SAR11_RS00635
uniprot id: Q4FPE1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

335992:SAR11 RS05610
gene id: 335992:SAR11_RS05610
uniprot id: Q4FLL2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

335992:SAR11 RS02920
gene id: 335992:SAR11_RS02920
uniprot id: Q4FN43
names: Function
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

335992:SAR11 RS03465
gene id: 335992:SAR11_RS03465
uniprot id: Q4FMT5
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

335992:SAR11 RS00605
gene id: 335992:SAR11_RS00605
uniprot id: Q4FPE7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell inner membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.

335992:SAR11 RS00585
gene id: 335992:SAR11_RS00585
uniprot id: Q4FPF1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

335992:SAR11 RS05150
gene id: 335992:SAR11_RS05150
uniprot id: Q4FLV3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

335992:SAR11 RS06690
gene id: 335992:SAR11_RS06690
uniprot id: Q4FKZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 1 family.
messages: Periplasm

335992:SAR11 RS01155
gene id: 335992:SAR11_RS01155
uniprot id: Q4FP36
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

335992:SAR11 RS05050
gene id: 335992:SAR11_RS05050
uniprot id: Q4FLX2
names: Similarity
messages: Belongs to the FBPase class 2 family.

335992:SAR11 RS05465
gene id: 335992:SAR11_RS05465
uniprot id: Q4FLP1
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

335992:SAR11 RS01555
gene id: 335992:SAR11_RS01555
uniprot id: Q4FNV7
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

335992:SAR11 RS04765
gene id: 335992:SAR11_RS04765
uniprot id: Q4FM25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

335992:SAR11 RS03220
gene id: 335992:SAR11_RS03220
uniprot id: Q4FMY4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

335992:SAR11 RS00025
gene id: 335992:SAR11_RS00025
uniprot id: Q4FPN1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Monomer.

335992:SAR11 RS04330
gene id: 335992:SAR11_RS04330
uniprot id: Q4FMB0
names: Similarity
messages: Belongs to the HIBADH-related family.

335992:SAR11 RS05190
gene id: 335992:SAR11_RS05190
uniprot id: Q4FLU5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

335992:SAR11 RS04480
gene id: 335992:SAR11_RS04480
uniprot id: Q4FM82
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

335992:SAR11 RS03820
gene id: 335992:SAR11_RS03820
uniprot id: Q4FML3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MsrQ family.
messages: Binds 1 FMN per subunit.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Cell inner membrane
messages: Heterodimer of a catalytic subunit (MsrP) and a heme-binding subunit (MsrQ).
messages: Membrane
messages: Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain.

335992:SAR11 RS02910
gene id: 335992:SAR11_RS02910
uniprot id: Q4FN45
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

335992:SAR11 RS01635
gene id: 335992:SAR11_RS01635
uniprot id: Q4FNU2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Essential cell division protein that coordinates cell division and chromosome segregation. The N-terminus is involved in assembly of the cell-division machinery. The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region. Translocation stops specifically at Xer-dif sites, where FtsK interacts with the Xer recombinase, allowing activation of chromosome unlinking by recombination. FtsK orienting polar sequences (KOPS) guide the direction of DNA translocation. FtsK can remove proteins from DNA as it translocates, but translocation stops specifically at XerCD-dif site, thereby preventing removal of XerC and XerD from dif.
messages: Homohexamer. Forms a ring that surrounds DNA.
messages: Membrane

335992:SAR11 RS01600
gene id: 335992:SAR11_RS01600
uniprot id: Q4FNU8
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

335992:SAR11 RS03195
gene id: 335992:SAR11_RS03195
uniprot id: Q4FMZ0
names: Similarity
messages: Belongs to the GST superfamily.

335992:SAR11 RS00180
gene id: 335992:SAR11_RS00180
uniprot id: Q4FPR3
names: Similarity
messages: Belongs to the MlaA family.

335992:SAR11 RS01225
gene id: 335992:SAR11_RS01225
uniprot id: Q4FP22
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

335992:SAR11 RS05195
gene id: 335992:SAR11_RS05195
uniprot id: Q4FLU4
names: Similarity
messages: Belongs to the UPF0174 family.

335992:SAR11 RS02305
gene id: 335992:SAR11_RS02305
uniprot id: Q4FNF9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.

335992:SAR11 RS00560
gene id: 335992:SAR11_RS00560
uniprot id: Q4FPF6
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

335992:SAR11 RS04410
gene id: 335992:SAR11_RS04410
uniprot id: Q4FM94
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

335992:SAR11 RS04965
gene id: 335992:SAR11_RS04965
uniprot id: Q4FLY7
names: Similarity
messages: Belongs to the SdhE FAD assembly factor family.

335992:SAR11 RS05505
gene id: 335992:SAR11_RS05505
uniprot id: Q4FLN3
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uL6 family.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

335992:SAR11 RS03225
gene id: 335992:SAR11_RS03225
uniprot id: Q4FMY3
names: Similarity
messages: Belongs to the peptidase S24 family.

335992:SAR11 RS02890
gene id: 335992:SAR11_RS02890
uniprot id: Q4FN48
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.
messages: Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

335992:SAR11 RS01660
gene id: 335992:SAR11_RS01660
uniprot id: Q4FNT7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

335992:SAR11 RS06225
gene id: 335992:SAR11_RS06225
uniprot id: Q4FL92
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

335992:SAR11 RS05570
gene id: 335992:SAR11_RS05570
uniprot id: Q4FLM0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

335992:SAR11 RS03415
gene id: 335992:SAR11_RS03415
uniprot id: Q4FMU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TspO/BZRP family.
messages: Membrane

335992:SAR11 RS01175
gene id: 335992:SAR11_RS01175
uniprot id: Q4FP32
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

335992:SAR11 RS03890
gene id: 335992:SAR11_RS03890
uniprot id: Q4FMJ9
names: Similarity
messages: Belongs to the ABC transporter superfamily.

335992:SAR11 RS01560
gene id: 335992:SAR11_RS01560
uniprot id: Q4FNV6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

335992:SAR11 RS01135
gene id: 335992:SAR11_RS01135
uniprot id: Q4FP40
names: Function
names: Similarity
messages: Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
messages: Belongs to the Nudix hydrolase family. RppH subfamily.

335992:SAR11 RS05140
gene id: 335992:SAR11_RS05140
uniprot id: Q4FLV5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

335992:SAR11 RS03885
gene id: 335992:SAR11_RS03885
uniprot id: Q4FMK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

335992:SAR11 RS00755
gene id: 335992:SAR11_RS00755
uniprot id: Q4FPB7
names: Function
names: Similarity
messages: Belongs to the LpxK family.
messages: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

335992:SAR11 RS06365
gene id: 335992:SAR11_RS06365
uniprot id: Q4FL63
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

335992:SAR11 RS03830
gene id: 335992:SAR11_RS03830
uniprot id: Q4FML1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaE family.
messages: Converts molybdopterin precursor Z into molybdopterin. This requires the incorporation of two sulfur atoms into precursor Z to generate a dithiolene group. The sulfur is provided by MoaD.
messages: Heterotetramer of 2 MoaD subunits and 2 MoaE subunits. Also stable as homodimer. The enzyme changes between these two forms during catalysis.

335992:SAR11 RS00520
gene id: 335992:SAR11_RS00520
uniprot id: Q4FPG3
names: Subunit
messages: Homodimer.

335992:SAR11 RS05520
gene id: 335992:SAR11_RS05520
uniprot id: Q4FLN0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

335992:SAR11 RS03065
gene id: 335992:SAR11_RS03065
uniprot id: Q4FN15
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

335992:SAR11 RS06230
gene id: 335992:SAR11_RS06230
uniprot id: Q4FL91
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

335992:SAR11 RS01010
gene id: 335992:SAR11_RS01010
uniprot id: Q4FP65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

335992:SAR11 RS02810
gene id: 335992:SAR11_RS02810
uniprot id: Q4FN65
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

335992:SAR11 RS01095
gene id: 335992:SAR11_RS01095
uniprot id: Q4FP48
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

335992:SAR11 RS01370
gene id: 335992:SAR11_RS01370
uniprot id: Q4FNZ3
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

335992:SAR11 RS01705
gene id: 335992:SAR11_RS01705
uniprot id: Q4FNS8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecB family.
messages: Cytoplasm
messages: Homotetramer, a dimer of dimers. One homotetramer interacts with 1 SecA dimer (By similarity).
messages: One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity).

335992:SAR11 RS02875
gene id: 335992:SAR11_RS02875
uniprot id: Q4FN51
names: Subcellular Location Annotation
messages: Membrane

335992:SAR11 RS03575
gene id: 335992:SAR11_RS03575
uniprot id: Q4FMR3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

335992:SAR11 RS00525
gene id: 335992:SAR11_RS00525
uniprot id: Q4FPG2
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

335992:SAR11 RS04625
gene id: 335992:SAR11_RS04625
uniprot id: Q4FM53
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.

335992:SAR11 RS02525
gene id: 335992:SAR11_RS02525
uniprot id: Q4FNB8
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

335992:SAR11 RS01795
gene id: 335992:SAR11_RS01795
uniprot id: Q4FNR0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

335992:SAR11 RS04530
gene id: 335992:SAR11_RS04530
uniprot id: Q4FM72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

335992:SAR11 RS03980
gene id: 335992:SAR11_RS03980
uniprot id: Q4FMI1
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

335992:SAR11 RS02285
gene id: 335992:SAR11_RS02285
uniprot id: Q4FNG4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

335992:SAR11 RS03095
gene id: 335992:SAR11_RS03095
uniprot id: Q4FN10
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.

335992:SAR11 RS04375
gene id: 335992:SAR11_RS04375
uniprot id: Q4FMA1
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

335992:SAR11 RS05920
gene id: 335992:SAR11_RS05920
uniprot id: Q4FLF4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

335992:SAR11 RS00410
gene id: 335992:SAR11_RS00410
uniprot id: Q4FPI5
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

335992:SAR11 RS04925
gene id: 335992:SAR11_RS04925
uniprot id: Q4FLZ5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

335992:SAR11 RS03525
gene id: 335992:SAR11_RS03525
uniprot id: Q4FMS3
names: Similarity
messages: Belongs to the prokaryotic GSH synthase family.

335992:SAR11 RS05430
gene id: 335992:SAR11_RS05430
uniprot id: Q4FLP8
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

335992:SAR11 RS05575
gene id: 335992:SAR11_RS05575
uniprot id: Q4FLL9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

335992:SAR11 RS03125
gene id: 335992:SAR11_RS03125
uniprot id: Q4FN04
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

335992:SAR11 RS06090
gene id: 335992:SAR11_RS06090
uniprot id: Q4FLB9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

335992:SAR11 RS01715
gene id: 335992:SAR11_RS01715
uniprot id: Q4FNS6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

335992:SAR11 RS02295
gene id: 335992:SAR11_RS02295
uniprot id: Q4FNG1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

335992:SAR11 RS05185
gene id: 335992:SAR11_RS05185
uniprot id: Q4FLU6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

335992:SAR11 RS06070
gene id: 335992:SAR11_RS06070
uniprot id: Q4FLC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell inner membrane
messages: Cell membrane

335992:SAR11 RS00935
gene id: 335992:SAR11_RS00935
uniprot id: Q4FP80
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

335992:SAR11 RS05385
gene id: 335992:SAR11_RS05385
uniprot id: Q4FLQ7
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

335992:SAR11 RS00600
gene id: 335992:SAR11_RS00600
uniprot id: Q4FPE8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase C chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.

335992:SAR11 RS01245
gene id: 335992:SAR11_RS01245
uniprot id: Q4FP18
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

335992:SAR11 RS03180
gene id: 335992:SAR11_RS03180
uniprot id: Q4FMZ3
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal/bacterial/fungal opsin family.
messages: Contains one covalently linked retinal chromophore.
messages: Membrane

335992:SAR11 RS05490
gene id: 335992:SAR11_RS05490
uniprot id: Q4FLN6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

335992:SAR11 RS00720
gene id: 335992:SAR11_RS00720
uniprot id: Q4FPC4
names: Similarity
messages: Belongs to the glutamate synthase family.

335992:SAR11 RS05480
gene id: 335992:SAR11_RS05480
uniprot id: Q4FLN8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Monomer.

335992:SAR11 RS01480
gene id: 335992:SAR11_RS01480
uniprot id: Q4FNX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PsiE family.
messages: Cell inner membrane
messages: Membrane

335992:SAR11 RS03530
gene id: 335992:SAR11_RS03530
uniprot id: Q4FMS2
names: Function
names: Similarity
messages: Belongs to the glutamate--cysteine ligase type 2 family. EgtA subfamily.
messages: Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC).

335992:SAR11 RS05005
gene id: 335992:SAR11_RS05005
uniprot id: Q4FLY0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily.
messages: Cytoplasm
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

335992:SAR11 RS02775
gene id: 335992:SAR11_RS02775
uniprot id: Q4FN72
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the gmhB family.
messages: Cytoplasm
messages: Monomer.

335992:SAR11 RS02350
gene id: 335992:SAR11_RS02350
uniprot id: Q4FNF0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell inner membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

335992:SAR11 RS05965
gene id: 335992:SAR11_RS05965
uniprot id: Q4FLE4
names: Function
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia.

335992:SAR11 RS03460
gene id: 335992:SAR11_RS03460
uniprot id: Q4FMT6
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

335992:SAR11 RS02105
gene id: 335992:SAR11_RS02105
uniprot id: Q4FNJ7
names: Subcellular Location Annotation
messages: Membrane

335992:SAR11 RS04440
gene id: 335992:SAR11_RS04440
uniprot id: Q4FM90
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity).