335543:SFUM RS02170
gene id: 335543:SFUM_RS02170
uniprot id: A0LFC2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.

335543:SFUM RS13405
gene id: 335543:SFUM_RS13405
uniprot id: A0LLG0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

335543:SFUM RS20260
gene id: 335543:SFUM_RS20260
uniprot id: A0LQ94
names: Function
names: Similarity
messages: Belongs to the ETF-QO/FixC family.
messages: Part of an electron transfer system.

335543:SFUM RS04545
gene id: 335543:SFUM_RS04545
uniprot id: A0LGM1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

335543:SFUM RS03660
gene id: 335543:SFUM_RS03660
uniprot id: A0LG50
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

335543:SFUM RS08820
gene id: 335543:SFUM_RS08820
uniprot id: A0LIZ2
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

335543:SFUM RS08700
gene id: 335543:SFUM_RS08700
uniprot id: A0LIW8
names: Function
names: Similarity
messages: Belongs to the phenylacetyl-CoA ligase family.
messages: Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).

335543:SFUM RS13950
gene id: 335543:SFUM_RS13950
uniprot id: A0LLR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

335543:SFUM RS18960
gene id: 335543:SFUM_RS18960
uniprot id: A0LPI4
names: Similarity
messages: Belongs to the GSP E family.

335543:SFUM RS02955
gene id: 335543:SFUM_RS02955
uniprot id: A0LFS0
names: Similarity
messages: Belongs to the P(II) protein family.

335543:SFUM RS14980
gene id: 335543:SFUM_RS14980
uniprot id: A0LMB0
names: Subcellular Location Annotation
messages: Membrane

335543:SFUM RS06415
gene id: 335543:SFUM_RS06415
uniprot id: A0LHM0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

335543:SFUM RS01925
gene id: 335543:SFUM_RS01925
uniprot id: A0LF76
names: Similarity
messages: Belongs to the leucine-binding protein family.

335543:SFUM RS17385
gene id: 335543:SFUM_RS17385
uniprot id: A0LNN6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

335543:SFUM RS13680
gene id: 335543:SFUM_RS13680
uniprot id: A0LLL3
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

335543:SFUM RS06060
gene id: 335543:SFUM_RS06060
uniprot id: A0LHF4
names: Function
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase family.
messages: CoA transferase having broad substrate specificity for short-chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons.

335543:SFUM RS03730
gene id: 335543:SFUM_RS03730
uniprot id: A0LG64
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.

335543:SFUM RS20980
gene id: 335543:SFUM_RS20980
uniprot id: A0LQN4
names: Subcellular Location Annotation
messages: Membrane

335543:SFUM RS13400
gene id: 335543:SFUM_RS13400
uniprot id: A0LLF9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

335543:SFUM RS11220
gene id: 335543:SFUM_RS11220
uniprot id: A0LK99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

335543:SFUM RS18520
gene id: 335543:SFUM_RS18520
uniprot id: A0LPA4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

335543:SFUM RS00405
gene id: 335543:SFUM_RS00405
uniprot id: A0LEC8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

335543:SFUM RS21870
gene id: 335543:SFUM_RS21870
uniprot id: A0LLH7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.

335543:SFUM RS03505
gene id: 335543:SFUM_RS03505
uniprot id: A0LG28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Cell membrane
messages: Membrane

335543:SFUM RS03345
gene id: 335543:SFUM_RS03345
uniprot id: A0LFZ7
names: Similarity
messages: Belongs to the universal stress protein A family.

335543:SFUM RS17120
gene id: 335543:SFUM_RS17120
uniprot id: A0LNI4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

335543:SFUM RS00650
gene id: 335543:SFUM_RS00650
uniprot id: A0LEH3
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

335543:SFUM RS09895
gene id: 335543:SFUM_RS09895
uniprot id: A0LJK0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

335543:SFUM RS17795
gene id: 335543:SFUM_RS17795
uniprot id: A0LNW5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HCP family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Binds 1 hybrid [4Fe-2O-2S] cluster.
messages: Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
messages: Cytoplasm

335543:SFUM RS01385
gene id: 335543:SFUM_RS01385
uniprot id: A0LEW9
names: Similarity
messages: Belongs to the tRNA methyltransferase O family.

335543:SFUM RS09920
gene id: 335543:SFUM_RS09920
uniprot id: A0LJK4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. NspC subfamily.
messages: Catalyzes the decarboxylation of carboxynorspermidine and carboxyspermidine.
messages: Cytoplasm
messages: Homodimer.

335543:SFUM RS03860
gene id: 335543:SFUM_RS03860
uniprot id: A0LG87
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

335543:SFUM RS07720
gene id: 335543:SFUM_RS07720
uniprot id: A0LIC8
names: Similarity
messages: Belongs to the peptidase A24 family.

335543:SFUM RS10620
gene id: 335543:SFUM_RS10620
uniprot id: A0LJY3
names: Subcellular Location Annotation
messages: Membrane

335543:SFUM RS19110
gene id: 335543:SFUM_RS19110
uniprot id: A0LPL5
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

335543:SFUM RS17520
gene id: 335543:SFUM_RS17520
uniprot id: A0LNR4
names: Similarity
messages: Belongs to the D-glutamate cyclase family.

335543:SFUM RS13375
gene id: 335543:SFUM_RS13375
uniprot id: A0LLF4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase Y family.
messages: Cell membrane
messages: Endoribonuclease that initiates mRNA decay.

335543:SFUM RS13420
gene id: 335543:SFUM_RS13420
uniprot id: A0LLG3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell inner membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

335543:SFUM RS20270
gene id: 335543:SFUM_RS20270
uniprot id: A0LQ96
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

335543:SFUM RS06745
gene id: 335543:SFUM_RS06745
uniprot id: A0LHT3
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

335543:SFUM RS21660
gene id: 335543:SFUM_RS21660
uniprot id: A0LIZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamD family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

335543:SFUM RS14615
gene id: 335543:SFUM_RS14615
uniprot id: A0LM45
names: Similarity
messages: Belongs to the UPF0251 family.

335543:SFUM RS11485
gene id: 335543:SFUM_RS11485
uniprot id: A0LKE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

335543:SFUM RS16870
gene id: 335543:SFUM_RS16870
uniprot id: A0LND3
names: Subcellular Location Annotation
messages: Membrane

335543:SFUM RS01010
gene id: 335543:SFUM_RS01010
uniprot id: A0LEP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

335543:SFUM RS01865
gene id: 335543:SFUM_RS01865
uniprot id: A0LF64
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

335543:SFUM RS08235
gene id: 335543:SFUM_RS08235
uniprot id: A0LIM7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell inner membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

335543:SFUM RS01795
gene id: 335543:SFUM_RS01795
uniprot id: A0LF50
names: Similarity
messages: Belongs to the universal stress protein A family.

335543:SFUM RS13525
gene id: 335543:SFUM_RS13525
uniprot id: A0LLI4
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

335543:SFUM RS01025
gene id: 335543:SFUM_RS01025
uniprot id: A0LEP7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

335543:SFUM RS14090
gene id: 335543:SFUM_RS14090
uniprot id: A0LLU4
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

335543:SFUM RS01640
gene id: 335543:SFUM_RS01640
uniprot id: A0LF21
names: Function
names: Similarity
messages: Belongs to the CobT family.
messages: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).

335543:SFUM RS10960
gene id: 335543:SFUM_RS10960
uniprot id: A0LK50
names: Similarity
messages: Belongs to the peptidase S49 family.

335543:SFUM RS21900
gene id: 335543:SFUM_RS21900
uniprot id: A0LLW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

335543:SFUM RS09205
gene id: 335543:SFUM_RS09205
uniprot id: A0LJ66
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

335543:SFUM RS08040
gene id: 335543:SFUM_RS08040
uniprot id: A0LII7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

335543:SFUM RS00520
gene id: 335543:SFUM_RS00520
uniprot id: A0LEE9
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

335543:SFUM RS12300
gene id: 335543:SFUM_RS12300
uniprot id: A0LKV7
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAL/histidase family.
messages: Contains an active site 4-methylidene-imidazol-5-one (MIO), which is formed autocatalytically by cyclization and dehydration of residues Ala-Ser-Gly.
messages: Cytoplasm

335543:SFUM RS08115
gene id: 335543:SFUM_RS08115
uniprot id: A0LIK2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

335543:SFUM RS13385
gene id: 335543:SFUM_RS13385
uniprot id: A0LLF6
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

335543:SFUM RS13470
gene id: 335543:SFUM_RS13470
uniprot id: A0LLH3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell inner membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

335543:SFUM RS03655
gene id: 335543:SFUM_RS03655
uniprot id: A0LG49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Membrane

335543:SFUM RS10740
gene id: 335543:SFUM_RS10740
uniprot id: A0LK06
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

335543:SFUM RS01955
gene id: 335543:SFUM_RS01955
uniprot id: A0LF82
names: Subcellular Location Annotation
messages: Membrane

335543:SFUM RS00225
gene id: 335543:SFUM_RS00225
uniprot id: A0LE92
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

335543:SFUM RS16365
gene id: 335543:SFUM_RS16365
uniprot id: A0LN36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

335543:SFUM RS00525
gene id: 335543:SFUM_RS00525
uniprot id: A0LEF0
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

335543:SFUM RS02485
gene id: 335543:SFUM_RS02485
uniprot id: A0LFI2
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

335543:SFUM RS12110
gene id: 335543:SFUM_RS12110
uniprot id: A0LKR9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peroxiredoxin family. Tpx subfamily.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

335543:SFUM RS20275
gene id: 335543:SFUM_RS20275
uniprot id: A0LQ97
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

335543:SFUM RS16620
gene id: 335543:SFUM_RS16620
uniprot id: A0LN85
names: Subcellular Location Annotation
messages: Cytoplasm

335543:SFUM RS14340
gene id: 335543:SFUM_RS14340
uniprot id: A0LLZ2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

335543:SFUM RS11030
gene id: 335543:SFUM_RS11030
uniprot id: A0LK61
names: Function
names: Similarity
messages: Belongs to the CbiD family.
messages: Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.

335543:SFUM RS16805
gene id: 335543:SFUM_RS16805
uniprot id: A0LNC1
names: Subcellular Location Annotation
messages: Membrane

335543:SFUM RS02210
gene id: 335543:SFUM_RS02210
uniprot id: A0LFD0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

335543:SFUM RS08505
gene id: 335543:SFUM_RS08505
uniprot id: A0LIS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

335543:SFUM RS15805
gene id: 335543:SFUM_RS15805
uniprot id: A0LMN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

335543:SFUM RS23740
gene id: 335543:SFUM_RS23740
uniprot id: A0LHR3
names: Subunit
messages: Heterodimer of a large and a small subunit.

335543:SFUM RS01880
gene id: 335543:SFUM_RS01880
uniprot id: A0LF67
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

335543:SFUM RS13410
gene id: 335543:SFUM_RS13410
uniprot id: A0LLG1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase delta chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

335543:SFUM RS00900
gene id: 335543:SFUM_RS00900
uniprot id: A0LEM3
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

335543:SFUM RS00965
gene id: 335543:SFUM_RS00965
uniprot id: A0LEN5
names: Function
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflC subfamily.
messages: HflC and HflK could regulate a protease.

335543:SFUM RS21140
gene id: 335543:SFUM_RS21140
uniprot id: A0LQR5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

335543:SFUM RS02830
gene id: 335543:SFUM_RS02830
uniprot id: A0LFP6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

335543:SFUM RS11505
gene id: 335543:SFUM_RS11505
uniprot id: A0LKF2
names: Subcellular Location Annotation
messages: Periplasm

335543:SFUM RS15920
gene id: 335543:SFUM_RS15920
uniprot id: A0LMU7
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

335543:SFUM RS06820
gene id: 335543:SFUM_RS06820
uniprot id: A0LHV0
names: Similarity
messages: Belongs to the xanthine dehydrogenase family.

335543:SFUM RS18900
gene id: 335543:SFUM_RS18900
uniprot id: A0LPH2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

335543:SFUM RS07150
gene id: 335543:SFUM_RS07150
uniprot id: A0LI14
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

335543:SFUM RS08850
gene id: 335543:SFUM_RS08850
uniprot id: A0LIZ8
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

335543:SFUM RS00540
gene id: 335543:SFUM_RS00540
uniprot id: A0LEF2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

335543:SFUM RS09265
gene id: 335543:SFUM_RS09265
uniprot id: A0LJ77
names: Subcellular Location Annotation
messages: Periplasm

335543:SFUM RS00010
gene id: 335543:SFUM_RS00010
uniprot id: A0LE54
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

335543:SFUM RS01815
gene id: 335543:SFUM_RS01815
uniprot id: A0LF54
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.

335543:SFUM RS01960
gene id: 335543:SFUM_RS01960
uniprot id: A0LF83
names: Subcellular Location Annotation
messages: Membrane

335543:SFUM RS19540
gene id: 335543:SFUM_RS19540
uniprot id: A0LPU6
names: Similarity
messages: Belongs to the peptidase S24 family.

335543:SFUM RS13925
gene id: 335543:SFUM_RS13925
uniprot id: A0LLR2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

335543:SFUM RS17870
gene id: 335543:SFUM_RS17870
uniprot id: A0LNX9
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

335543:SFUM RS02305
gene id: 335543:SFUM_RS02305
uniprot id: A0LFE8
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

335543:SFUM RS05725
gene id: 335543:SFUM_RS05725
uniprot id: A0LH92
names: Function
names: Similarity
messages: Belongs to the CbiK family.
messages: Catalyzes the insertion of Co(2+) into sirohydrochlorin.

335543:SFUM RS13830
gene id: 335543:SFUM_RS13830
uniprot id: A0LLP4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Cytoplasm
messages: Homodimer.

335543:SFUM RS02275
gene id: 335543:SFUM_RS02275
uniprot id: A0LFE3
names: Subcellular Location Annotation
messages: Membrane

335543:SFUM RS01110
gene id: 335543:SFUM_RS01110
uniprot id: A0LER4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

335543:SFUM RS05420
gene id: 335543:SFUM_RS05420
uniprot id: A0LH34
names: Similarity
messages: Belongs to the universal stress protein A family.

335543:SFUM RS13480
gene id: 335543:SFUM_RS13480
uniprot id: A0LLH5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.

335543:SFUM RS06660
gene id: 335543:SFUM_RS06660
uniprot id: A0LHR8
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

335543:SFUM RS14055
gene id: 335543:SFUM_RS14055
uniprot id: A0LLT8
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

335543:SFUM RS09425
gene id: 335543:SFUM_RS09425
uniprot id: A0LJA8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

335543:SFUM RS05275
gene id: 335543:SFUM_RS05275
uniprot id: A0LH07
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NifD/NifK/NifE/NifN family.
messages: Binds 1 [8Fe-7S] cluster per heterodimer.
messages: Tetramer of two alpha and two beta chains. Forms complex with the iron protein (nitrogenase component 2).
messages: This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation.

335543:SFUM RS06400
gene id: 335543:SFUM_RS06400
uniprot id: A0LHL7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

335543:SFUM RS19410
gene id: 335543:SFUM_RS19410
uniprot id: A0LPS0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Cell inner membrane
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.

335543:SFUM RS14260
gene id: 335543:SFUM_RS14260
uniprot id: A0LLX8
names: Subcellular Location Annotation
messages: Membrane

335543:SFUM RS14280
gene id: 335543:SFUM_RS14280
uniprot id: A0LLY1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell inner membrane
messages: Membrane

335543:SFUM RS08060
gene id: 335543:SFUM_RS08060
uniprot id: A0LIJ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

335543:SFUM RS01690
gene id: 335543:SFUM_RS01690
uniprot id: A0LF30
names: Subcellular Location Annotation
messages: Membrane

335543:SFUM RS16215
gene id: 335543:SFUM_RS16215
uniprot id: A0LN06
names: Similarity
messages: Belongs to the deoxyhypusine synthase family.

335543:SFUM RS08110
gene id: 335543:SFUM_RS08110
uniprot id: A0LIK1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

335543:SFUM RS00655
gene id: 335543:SFUM_RS00655
uniprot id: A0LEH4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

335543:SFUM RS08985
gene id: 335543:SFUM_RS08985
uniprot id: A0LJ24
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.

335543:SFUM RS03490
gene id: 335543:SFUM_RS03490
uniprot id: A0LG25
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

335543:SFUM RS12155
gene id: 335543:SFUM_RS12155
uniprot id: A0LKS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 13 family.
messages: Cytoplasm

335543:SFUM RS13645
gene id: 335543:SFUM_RS13645
uniprot id: A0LLK7
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

335543:SFUM RS18290
gene id: 335543:SFUM_RS18290
uniprot id: A0LP60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

335543:SFUM RS15310
gene id: 335543:SFUM_RS15310
uniprot id: A0LMH4
names: Similarity
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.

335543:SFUM RS13535
gene id: 335543:SFUM_RS13535
uniprot id: A0LLI6
names: Function
names: Similarity
messages: Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor.
messages: Belongs to the biotin--protein ligase family.

335543:SFUM RS03575
gene id: 335543:SFUM_RS03575
uniprot id: A0LG39
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

335543:SFUM RS04025
gene id: 335543:SFUM_RS04025
uniprot id: A0LGC0
names: Caution
names: Function
names: Similarity
messages: Belongs to the APS kinase family.
messages: Catalyzes the synthesis of activated sulfate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

335543:SFUM RS17905
gene id: 335543:SFUM_RS17905
uniprot id: A0LNY6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

335543:SFUM RS08170
gene id: 335543:SFUM_RS08170
uniprot id: A0LIL4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

335543:SFUM RS13425
gene id: 335543:SFUM_RS13425
uniprot id: A0LLG4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. MrdB/RodA subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell wall elongation.

335543:SFUM RS12055
gene id: 335543:SFUM_RS12055
uniprot id: A0LKR0
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

335543:SFUM RS03215
gene id: 335543:SFUM_RS03215
uniprot id: A0LFX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

335543:SFUM RS14010
gene id: 335543:SFUM_RS14010
uniprot id: A0LLT0
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

335543:SFUM RS09625
gene id: 335543:SFUM_RS09625
uniprot id: A0LJE6
names: Similarity
messages: Belongs to the LOG family.

335543:SFUM RS03510
gene id: 335543:SFUM_RS03510
uniprot id: A0LG29
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

335543:SFUM RS15025
gene id: 335543:SFUM_RS15025
uniprot id: A0LMB9
names: Function
names: Similarity
messages: Belongs to the methylglyoxal synthase family.
messages: Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.

335543:SFUM RS22125
gene id: 335543:SFUM_RS22125
uniprot id: A0LPF4
names: Subcellular Location Annotation
messages: Cytoplasm

335543:SFUM RS16155
gene id: 335543:SFUM_RS16155
uniprot id: A0LMZ5
names: Subcellular Location Annotation
messages: Membrane

335543:SFUM RS15545
gene id: 335543:SFUM_RS15545
uniprot id: A0LMM1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

335543:SFUM RS06350
gene id: 335543:SFUM_RS06350
uniprot id: A0LHK8
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

335543:SFUM RS20140
gene id: 335543:SFUM_RS20140
uniprot id: A0LQ69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

335543:SFUM RS12870
gene id: 335543:SFUM_RS12870
uniprot id: A0LL68
names: Similarity
messages: Belongs to the FeoA family.

335543:SFUM RS07360
gene id: 335543:SFUM_RS07360
uniprot id: A0LI57
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

335543:SFUM RS00150
gene id: 335543:SFUM_RS00150
uniprot id: A0LE76
names: Similarity
messages: Belongs to the Fur family.

335543:SFUM RS16885
gene id: 335543:SFUM_RS16885
uniprot id: A0LND6
names: Function
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia.

335543:SFUM RS09660
gene id: 335543:SFUM_RS09660
uniprot id: A0LJF2
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT.

335543:SFUM RS09845
gene id: 335543:SFUM_RS09845
uniprot id: A0LJJ0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

335543:SFUM RS10660
gene id: 335543:SFUM_RS10660
uniprot id: A0LJZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

335543:SFUM RS02560
gene id: 335543:SFUM_RS02560
uniprot id: A0LFJ5
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family.

335543:SFUM RS05695
gene id: 335543:SFUM_RS05695
uniprot id: A0LH86
names: Similarity
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family. Bacterial alpha-2-macroglobulin subfamily.

335543:SFUM RS15550
gene id: 335543:SFUM_RS15550
uniprot id: A0LMM2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

335543:SFUM RS18125
gene id: 335543:SFUM_RS18125
uniprot id: A0LP29
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

335543:SFUM RS16580
gene id: 335543:SFUM_RS16580
uniprot id: A0LN77
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIS family. GmhA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
messages: Cytoplasm
messages: Homotetramer.
messages: The reaction produces a racemic mixture of D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate.

335543:SFUM RS19270
gene id: 335543:SFUM_RS19270
uniprot id: A0LPP6
names: Subcellular Location Annotation
messages: Membrane

335543:SFUM RS01405
gene id: 335543:SFUM_RS01405
uniprot id: A0LEX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpxP/Spy family.
messages: Periplasm

335543:SFUM RS23605
gene id: 335543:SFUM_RS23605
uniprot id: A0LNR9
names: Subcellular Location Annotation
messages: Membrane

335543:SFUM RS17190
gene id: 335543:SFUM_RS17190
uniprot id: A0LNJ8
names: Subcellular Location Annotation
messages: Membrane

335543:SFUM RS17060
gene id: 335543:SFUM_RS17060
uniprot id: A0LNH2
names: Subcellular Location Annotation
messages: Membrane

335543:SFUM RS08045
gene id: 335543:SFUM_RS08045
uniprot id: A0LIH6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

335543:SFUM RS09045
gene id: 335543:SFUM_RS09045
uniprot id: A0LJ36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CbiQ family.
messages: Membrane

335543:SFUM RS03640
gene id: 335543:SFUM_RS03640
uniprot id: A0LG46
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

335543:SFUM RS17495
gene id: 335543:SFUM_RS17495
uniprot id: A0LNQ9
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: May be specifically involved in the processing, transport, and/or maturation of the MADH beta-subunit.
messages: Membrane

335543:SFUM RS00450
gene id: 335543:SFUM_RS00450
uniprot id: A0LED7
names: Subcellular Location Annotation
messages: Membrane

335543:SFUM RS08160
gene id: 335543:SFUM_RS08160
uniprot id: A0LIL2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

335543:SFUM RS10200
gene id: 335543:SFUM_RS10200
uniprot id: A0LJQ2
names: Cofactor
names: Similarity
messages: Belongs to the PyrK family.
messages: Binds 1 [2Fe-2S] cluster per subunit.

335543:SFUM RS07885
gene id: 335543:SFUM_RS07885
uniprot id: A0LIF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

335543:SFUM RS05160
gene id: 335543:SFUM_RS05160
uniprot id: A0LGY4
names: Similarity
messages: Belongs to the peptidase C40 family.

335543:SFUM RS11350
gene id: 335543:SFUM_RS11350
uniprot id: A0LKC5
names: Similarity
messages: Belongs to the peptidase C40 family.

335543:SFUM RS06335
gene id: 335543:SFUM_RS06335
uniprot id: A0LHK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

335543:SFUM RS18920
gene id: 335543:SFUM_RS18920
uniprot id: A0LPH6
names: Similarity
messages: Belongs to the bacterial secretin family. GSP D subfamily.

335543:SFUM RS05505
gene id: 335543:SFUM_RS05505
uniprot id: A0LH50
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

335543:SFUM RS12295
gene id: 335543:SFUM_RS12295
uniprot id: A0LKV6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. HutI family.
messages: Binds 1 zinc or iron ion per subunit.
messages: Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate. It is the third step in the universal histidine degradation pathway.
messages: Cytoplasm

335543:SFUM RS03700
gene id: 335543:SFUM_RS03700
uniprot id: A0LG58
names: Similarity
messages: Belongs to the D-alanine--D-alanine ligase family.

335543:SFUM RS09850
gene id: 335543:SFUM_RS09850
uniprot id: A0LJJ1
names: Similarity
messages: Belongs to the tRNA methyltransferase O family.

335543:SFUM RS18515
gene id: 335543:SFUM_RS18515
uniprot id: A0LPA3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

335543:SFUM RS07900
gene id: 335543:SFUM_RS07900
uniprot id: A0LIG1
names: Similarity
messages: Belongs to the ros/MucR family.

335543:SFUM RS10910
gene id: 335543:SFUM_RS10910
uniprot id: A0LK40
names: Subcellular Location Annotation
messages: Membrane

335543:SFUM RS03755
gene id: 335543:SFUM_RS03755
uniprot id: A0LG69
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell inner membrane
messages: Membrane

335543:SFUM RS16260
gene id: 335543:SFUM_RS16260
uniprot id: A0LN15
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

335543:SFUM RS01070
gene id: 335543:SFUM_RS01070
uniprot id: A0LEQ6
names: Subcellular Location Annotation
messages: Membrane

335543:SFUM RS20690
gene id: 335543:SFUM_RS20690
uniprot id: A0LQH9
names: Similarity
messages: Belongs to the HypE family.

335543:SFUM RS19720
gene id: 335543:SFUM_RS19720
uniprot id: A0LPY2
names: Similarity
messages: Belongs to the myoviridae tail sheath protein family.

335543:SFUM RS15510
gene id: 335543:SFUM_RS15510
uniprot id: A0LML4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

335543:SFUM RS08690
gene id: 335543:SFUM_RS08690
uniprot id: A0LIW6
names: Similarity
messages: Belongs to the leucine-binding protein family.

335543:SFUM RS14730
gene id: 335543:SFUM_RS14730
uniprot id: A0LM65
names: Subcellular Location Annotation
messages: Membrane

335543:SFUM RS18090
gene id: 335543:SFUM_RS18090
uniprot id: A0LP23
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

335543:SFUM RS07225
gene id: 335543:SFUM_RS07225
uniprot id: A0LI30
names: Subcellular Location Annotation
messages: Membrane

335543:SFUM RS01975
gene id: 335543:SFUM_RS01975
uniprot id: A0LF86
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

335543:SFUM RS01095
gene id: 335543:SFUM_RS01095
uniprot id: A0LER1
names: Similarity
messages: Belongs to the DprA/Smf family.

335543:SFUM RS10890
gene id: 335543:SFUM_RS10890
uniprot id: A0LK36
names: Similarity
messages: Belongs to the citrate synthase family.

335543:SFUM RS09000
gene id: 335543:SFUM_RS09000
uniprot id: A0LJ27
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

335543:SFUM RS05735
gene id: 335543:SFUM_RS05735
uniprot id: A0LH94
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Part of an ABC transporter complex. Responsible for energy coupling to the transport system.

335543:SFUM RS03495
gene id: 335543:SFUM_RS03495
uniprot id: A0LG26
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

335543:SFUM RS13935
gene id: 335543:SFUM_RS13935
uniprot id: A0LLR4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

335543:SFUM RS01055
gene id: 335543:SFUM_RS01055
uniprot id: A0LEQ3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

335543:SFUM RS01595
gene id: 335543:SFUM_RS01595
uniprot id: A0LF12
names: Subcellular Location Annotation
messages: Membrane

335543:SFUM RS02635
gene id: 335543:SFUM_RS02635
uniprot id: A0LFL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0394 family.
messages: Membrane

335543:SFUM RS16680
gene id: 335543:SFUM_RS16680
uniprot id: A0LN97
names: Similarity
messages: Belongs to the universal stress protein A family.

335543:SFUM RS03360
gene id: 335543:SFUM_RS03360
uniprot id: A0LG00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

335543:SFUM RS06285
gene id: 335543:SFUM_RS06285
uniprot id: A0LHJ6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.

335543:SFUM RS11060
gene id: 335543:SFUM_RS11060
uniprot id: A0LK67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0182 family.
messages: Cell membrane

335543:SFUM RS00350
gene id: 335543:SFUM_RS00350
uniprot id: A0LEB7
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

335543:SFUM RS09375
gene id: 335543:SFUM_RS09375
uniprot id: A0LJ98
names: Function
names: Similarity
messages: Belongs to the MqnA/MqnD family. MqnD subfamily.
messages: Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).

335543:SFUM RS07125
gene id: 335543:SFUM_RS07125
uniprot id: A0LI09
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

335543:SFUM RS15800
gene id: 335543:SFUM_RS15800
uniprot id: A0LMS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

335543:SFUM RS05005
gene id: 335543:SFUM_RS05005
uniprot id: A0LGV7
names: Subcellular Location Annotation
messages: Membrane

335543:SFUM RS18935
gene id: 335543:SFUM_RS18935
uniprot id: A0LPH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP K family.
messages: Cell inner membrane
messages: Membrane

335543:SFUM RS02590
gene id: 335543:SFUM_RS02590
uniprot id: A0LFK2
names: Similarity
messages: Belongs to the ros/MucR family.

335543:SFUM RS06360
gene id: 335543:SFUM_RS06360
uniprot id: A0LHL0
names: Function
messages: Translation factor necessary for the incorporation of selenocysteine into proteins. It probably replaces EF-Tu for the insertion of selenocysteine directed by the UGA codon. SelB binds GTP and GDP.

335543:SFUM RS08470
gene id: 335543:SFUM_RS08470
uniprot id: A0LIS1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).

335543:SFUM RS14860
gene id: 335543:SFUM_RS14860
uniprot id: A0LM89
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
messages: Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.
messages: Cytoplasm

335543:SFUM RS11215
gene id: 335543:SFUM_RS11215
uniprot id: A0LK98
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

335543:SFUM RS13070
gene id: 335543:SFUM_RS13070
uniprot id: A0LLA5
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

335543:SFUM RS02615
gene id: 335543:SFUM_RS02615
uniprot id: A0LFK7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M15D family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide.

335543:SFUM RS03275
gene id: 335543:SFUM_RS03275
uniprot id: A0LFY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

335543:SFUM RS21780
gene id: 335543:SFUM_RS21780
uniprot id: A0LKQ0
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG).

335543:SFUM RS02895
gene id: 335543:SFUM_RS02895
uniprot id: A0LFQ8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

335543:SFUM RS08635
gene id: 335543:SFUM_RS08635
uniprot id: A0LIV5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptD family.
messages: Cell outer membrane
messages: Component of the lipopolysaccharide transport and assembly complex.
messages: Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

335543:SFUM RS10940
gene id: 335543:SFUM_RS10940
uniprot id: A0LK46
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

335543:SFUM RS06665
gene id: 335543:SFUM_RS06665
uniprot id: A0LHR9
names: Similarity
messages: Belongs to the 5'(3')-deoxyribonucleotidase family.

335543:SFUM RS13940
gene id: 335543:SFUM_RS13940
uniprot id: A0LLR5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

335543:SFUM RS17205
gene id: 335543:SFUM_RS17205
uniprot id: A0LNK1
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

335543:SFUM RS09915
gene id: 335543:SFUM_RS09915
uniprot id: A0LJK3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Monomer.

335543:SFUM RS02140
gene id: 335543:SFUM_RS02140
uniprot id: A0LFB7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

335543:SFUM RS07390
gene id: 335543:SFUM_RS07390
uniprot id: A0LI63
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.

335543:SFUM RS07305
gene id: 335543:SFUM_RS07305
uniprot id: A0LI46
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

335543:SFUM RS03815
gene id: 335543:SFUM_RS03815
uniprot id: A0LG79
names: Subcellular Location Annotation
messages: Cytoplasm

335543:SFUM RS07945
gene id: 335543:SFUM_RS07945
uniprot id: A0LIG9
names: Similarity
messages: Belongs to the citrate synthase family.

335543:SFUM RS00640
gene id: 335543:SFUM_RS00640
uniprot id: A0LEH1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

335543:SFUM RS07990
gene id: 335543:SFUM_RS07990
uniprot id: A0LIH6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

335543:SFUM RS09170
gene id: 335543:SFUM_RS09170
uniprot id: A0LJ59
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.

335543:SFUM RS08380
gene id: 335543:SFUM_RS08380
uniprot id: A0LIQ4
names: Similarity
messages: Belongs to the leucine-binding protein family.

335543:SFUM RS09345
gene id: 335543:SFUM_RS09345
uniprot id: A0LJ92
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

335543:SFUM RS07160
gene id: 335543:SFUM_RS07160
uniprot id: A0LI16
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.

335543:SFUM RS09365
gene id: 335543:SFUM_RS09365
uniprot id: A0LJ96
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

335543:SFUM RS20890
gene id: 335543:SFUM_RS20890
uniprot id: A0LQL9
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Feedback inhibited by histidine.

335543:SFUM RS10885
gene id: 335543:SFUM_RS10885
uniprot id: A0LK35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Cell inner membrane
messages: Membrane

335543:SFUM RS02750
gene id: 335543:SFUM_RS02750
uniprot id: A0LFN0
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

335543:SFUM RS07610
gene id: 335543:SFUM_RS07610
uniprot id: A0LIA5
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

335543:SFUM RS05715
gene id: 335543:SFUM_RS05715
uniprot id: A0LH90
names: Subcellular Location Annotation
messages: Membrane

335543:SFUM RS04095
gene id: 335543:SFUM_RS04095
uniprot id: A0LGD5
names: Subcellular Location Annotation
messages: Membrane

335543:SFUM RS07130
gene id: 335543:SFUM_RS07130
uniprot id: A0LI10
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

335543:SFUM RS11245
gene id: 335543:SFUM_RS11245
uniprot id: A0LKA4
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

335543:SFUM RS15595
gene id: 335543:SFUM_RS15595
uniprot id: A0LMN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

335543:SFUM RS15340
gene id: 335543:SFUM_RS15340
uniprot id: A0LMI0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Atypical ATP-dependent clade 'X' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homodimer.

335543:SFUM RS20255
gene id: 335543:SFUM_RS20255
uniprot id: A0LQ93
names: Function
messages: Could be a 3Fe-4S cluster-containing protein.

335543:SFUM RS03430
gene id: 335543:SFUM_RS03430
uniprot id: A0LG13
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

335543:SFUM RS18605
gene id: 335543:SFUM_RS18605
uniprot id: A0LPC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Cell membrane
messages: Membrane

335543:SFUM RS00645
gene id: 335543:SFUM_RS00645
uniprot id: A0LEH2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

335543:SFUM RS14135
gene id: 335543:SFUM_RS14135
uniprot id: A0LLV4
names: Similarity
messages: Belongs to the archease family.

335543:SFUM RS03315
gene id: 335543:SFUM_RS03315
uniprot id: A0LFZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

335543:SFUM RS21655
gene id: 335543:SFUM_RS21655
uniprot id: A0LIT7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

335543:SFUM RS14080
gene id: 335543:SFUM_RS14080
uniprot id: A0LLU3
names: Similarity
messages: Belongs to the peptidase A31 family.

335543:SFUM RS01330
gene id: 335543:SFUM_RS01330
uniprot id: A0LEV9
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

335543:SFUM RS06310
gene id: 335543:SFUM_RS06310
uniprot id: A0LHK1
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

335543:SFUM RS19485
gene id: 335543:SFUM_RS19485
uniprot id: A0LPT5
names: Function
names: Similarity
messages: Belongs to the DtxR/MntR family.
messages: In the presence of manganese, represses expression of mntH and mntS. Up-regulates expression of mntP.

335543:SFUM RS04815
gene id: 335543:SFUM_RS04815
uniprot id: A0LGS2
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.

335543:SFUM RS01080
gene id: 335543:SFUM_RS01080
uniprot id: A0LEQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

335543:SFUM RS05595
gene id: 335543:SFUM_RS05595
uniprot id: A0LH68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

335543:SFUM RS03535
gene id: 335543:SFUM_RS03535
uniprot id: A0LG33
names: Subcellular Location Annotation
messages: Membrane

335543:SFUM RS01555
gene id: 335543:SFUM_RS01555
uniprot id: A0LF03
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

335543:SFUM RS11205
gene id: 335543:SFUM_RS11205
uniprot id: A0LK96
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.

335543:SFUM RS18320
gene id: 335543:SFUM_RS18320
uniprot id: A0LP65
names: Function
names: Similarity
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.
messages: E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

335543:SFUM RS15740
gene id: 335543:SFUM_RS15740
uniprot id: A0LML8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

335543:SFUM RS16660
gene id: 335543:SFUM_RS16660
uniprot id: A0LN93
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.
messages: Rubredoxin is a small nonheme, iron protein lacking acid-labile sulfide. Its single Fe, chelated to 4 Cys, functions as an electron acceptor and may also stabilize the conformation of the molecule.

335543:SFUM RS21680
gene id: 335543:SFUM_RS21680
uniprot id: A0LJ68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

335543:SFUM RS02415
gene id: 335543:SFUM_RS02415
uniprot id: A0LFG9
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

335543:SFUM RS17375
gene id: 335543:SFUM_RS17375
uniprot id: A0LNN5
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.
messages: Cell inner membrane
messages: Inhibited by the protonophore carbonyl cyanide m-chlorophenylhydrazone (CCCP), but not by valinomycin.
messages: Proton-coupled L-lactate specific transporter.

335543:SFUM RS08475
gene id: 335543:SFUM_RS08475
uniprot id: A0LIS2
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

335543:SFUM RS00305
gene id: 335543:SFUM_RS00305
uniprot id: A0LEA8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

335543:SFUM RS02515
gene id: 335543:SFUM_RS02515
uniprot id: A0LFI6
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.

335543:SFUM RS10920
gene id: 335543:SFUM_RS10920
uniprot id: A0LK42
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

335543:SFUM RS01845
gene id: 335543:SFUM_RS01845
uniprot id: A0LF60
names: Similarity
messages: Belongs to the peptidase M16 family.

335543:SFUM RS21520
gene id: 335543:SFUM_RS21520
uniprot id: A0LHS0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MinC family.
messages: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.
messages: Interacts with MinD and FtsZ.

335543:SFUM RS11240
gene id: 335543:SFUM_RS11240
uniprot id: A0LKA3
names: Similarity
messages: Belongs to the aspartokinase family.

335543:SFUM RS06675
gene id: 335543:SFUM_RS06675
uniprot id: A0LHS1
names: Function
names: Similarity
names: Subunit
messages: ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.
messages: Belongs to the ParA family. MinD subfamily.
messages: Interacts with MinC and FtsZ.

335543:SFUM RS09855
gene id: 335543:SFUM_RS09855
uniprot id: A0LJJ2
names: Function
names: Similarity
messages: Belongs to the RecD family. RecD-like subfamily.
messages: DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity.

335543:SFUM RS04185
gene id: 335543:SFUM_RS04185
uniprot id: A0LGF2
names: Similarity
messages: Belongs to the universal stress protein A family.

335543:SFUM RS11045
gene id: 335543:SFUM_RS11045
uniprot id: A0LK64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

335543:SFUM RS08875
gene id: 335543:SFUM_RS08875
uniprot id: A0LJ03
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

335543:SFUM RS23735
gene id: 335543:SFUM_RS23735
uniprot id: A0LHP2
names: Subcellular Location Annotation
messages: Membrane

335543:SFUM RS10975
gene id: 335543:SFUM_RS10975
uniprot id: A0LK53
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

335543:SFUM RS17160
gene id: 335543:SFUM_RS17160
uniprot id: A0LNJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the etk/wzc family.
messages: Cell inner membrane
messages: Membrane

335543:SFUM RS04060
gene id: 335543:SFUM_RS04060
uniprot id: A0LGC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Membrane

335543:SFUM RS06760
gene id: 335543:SFUM_RS06760
uniprot id: A0LHT7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.
messages: Cytoplasm
messages: Homodimer.

335543:SFUM RS06405
gene id: 335543:SFUM_RS06405
uniprot id: A0LHL8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

335543:SFUM RS17445
gene id: 335543:SFUM_RS17445
uniprot id: A0LNP9
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

335543:SFUM RS10900
gene id: 335543:SFUM_RS10900
uniprot id: A0LK38
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

335543:SFUM RS03395
gene id: 335543:SFUM_RS03395
uniprot id: A0LG07
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

335543:SFUM RS03950
gene id: 335543:SFUM_RS03950
uniprot id: A0LGA4
names: Subcellular Location Annotation
messages: Cell outer membrane

335543:SFUM RS10320
gene id: 335543:SFUM_RS10320
uniprot id: A0LJS4
names: Similarity
messages: Belongs to the YkuD family.

335543:SFUM RS18685
gene id: 335543:SFUM_RS18685
uniprot id: A0LPD5
names: Similarity
messages: Belongs to the PspA/IM30 family.

335543:SFUM RS10665
gene id: 335543:SFUM_RS10665
uniprot id: A0LJZ1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

335543:SFUM RS08630
gene id: 335543:SFUM_RS08630
uniprot id: A0LIV4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

335543:SFUM RS11210
gene id: 335543:SFUM_RS11210
uniprot id: A0LK97
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

335543:SFUM RS15000
gene id: 335543:SFUM_RS15000
uniprot id: A0LMB4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

335543:SFUM RS17050
gene id: 335543:SFUM_RS17050
uniprot id: A0LNH0
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

335543:SFUM RS11955
gene id: 335543:SFUM_RS11955
uniprot id: A0LKP2
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. Nitrilase family.

335543:SFUM RS07140
gene id: 335543:SFUM_RS07140
uniprot id: A0LI12
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

335543:SFUM RS13495
gene id: 335543:SFUM_RS13495
uniprot id: A0LLH8
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

335543:SFUM RS15670
gene id: 335543:SFUM_RS15670
uniprot id: A0LMK4
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

335543:SFUM RS16050
gene id: 335543:SFUM_RS16050
uniprot id: A0LMX4
names: Subcellular Location Annotation
messages: Membrane

335543:SFUM RS17450
gene id: 335543:SFUM_RS17450
uniprot id: A0LNQ0
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

335543:SFUM RS08620
gene id: 335543:SFUM_RS08620
uniprot id: A0LIV2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

335543:SFUM RS00240
gene id: 335543:SFUM_RS00240
uniprot id: A0LE95
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

335543:SFUM RS09210
gene id: 335543:SFUM_RS09210
uniprot id: A0LJ67
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

335543:SFUM RS04460
gene id: 335543:SFUM_RS04460
uniprot id: A0LGK3
names: Subcellular Location Annotation
messages: Membrane

335543:SFUM RS18050
gene id: 335543:SFUM_RS18050
uniprot id: A0LP15
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
messages: Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD).

335543:SFUM RS10925
gene id: 335543:SFUM_RS10925
uniprot id: A0LK43
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

335543:SFUM RS14670
gene id: 335543:SFUM_RS14670
uniprot id: A0LM56
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

335543:SFUM RS03350
gene id: 335543:SFUM_RS03350
uniprot id: A0LFZ8
names: Subcellular Location Annotation
messages: Membrane

335543:SFUM RS20195
gene id: 335543:SFUM_RS20195
uniprot id: A0LQ81
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

335543:SFUM RS10040
gene id: 335543:SFUM_RS10040
uniprot id: A0LJM5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cell inner membrane
messages: In the C-terminal section; belongs to the complex I 49 kDa subunit family.
messages: In the N-terminal section; belongs to the complex I 20 kDa subunit family.
messages: In the central section; belongs to the complex I 30 kDa subunit family.
messages: NDH-1 is composed of about 13 different subunits. Subunits NuoBCD, E, F, and G constitute the peripheral sector of the complex (By similarity).
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

335543:SFUM RS23530
gene id: 335543:SFUM_RS23530
uniprot id: A0LJR6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

335543:SFUM RS14160
gene id: 335543:SFUM_RS14160
uniprot id: A0LLV9
names: Function
names: Similarity
messages: Adenine glycosylase active on G-A mispairs. MutY also corrects error-prone DNA synthesis past GO lesions which are due to the oxidatively damaged form of guanine: 7,8-dihydro-8-oxoguanine (8-oxo-dGTP).
messages: Belongs to the Nth/MutY family.

335543:SFUM RS15965
gene id: 335543:SFUM_RS15965
uniprot id: A0LMV7
names: Function
names: Similarity
messages: Belongs to the MqnA/MqnD family. MqnA subfamily.
messages: Catalyzes the dehydration of chorismate into 3-[(1-carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).

335543:SFUM RS09165
gene id: 335543:SFUM_RS09165
uniprot id: A0LJ58
names: Similarity
messages: Belongs to the TrpC family.

335543:SFUM RS07220
gene id: 335543:SFUM_RS07220
uniprot id: A0LI29
names: Subcellular Location Annotation
messages: Membrane

335543:SFUM RS19380
gene id: 335543:SFUM_RS19380
uniprot id: A0LPR5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

335543:SFUM RS00410
gene id: 335543:SFUM_RS00410
uniprot id: A0LEC9
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

335543:SFUM RS11820
gene id: 335543:SFUM_RS11820
uniprot id: A0LKL7
names: Similarity
messages: Belongs to the AOR/FOR family.

335543:SFUM RS08800
gene id: 335543:SFUM_RS08800
uniprot id: A0LIY8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

335543:SFUM RS17360
gene id: 335543:SFUM_RS17360
uniprot id: A0LNN3
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.
messages: Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

335543:SFUM RS08795
gene id: 335543:SFUM_RS08795
uniprot id: A0LIY7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

335543:SFUM RS16785
gene id: 335543:SFUM_RS16785
uniprot id: A0LNB7
names: Similarity
messages: Belongs to the peptidase S58 family.

335543:SFUM RS18780
gene id: 335543:SFUM_RS18780
uniprot id: A0LPE9
names: Similarity
messages: Belongs to the RemA family.

335543:SFUM RS08105
gene id: 335543:SFUM_RS08105
uniprot id: A0LIK0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

335543:SFUM RS13740
gene id: 335543:SFUM_RS13740
uniprot id: A0LLM5
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

335543:SFUM RS20765
gene id: 335543:SFUM_RS20765
uniprot id: A0LQJ5
names: Subcellular Location Annotation
messages: Membrane

335543:SFUM RS09150
gene id: 335543:SFUM_RS09150
uniprot id: A0LJ55
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

335543:SFUM RS20060
gene id: 335543:SFUM_RS20060
uniprot id: A0LQ54
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

335543:SFUM RS00605
gene id: 335543:SFUM_RS00605
uniprot id: A0LEG4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

335543:SFUM RS13960
gene id: 335543:SFUM_RS13960
uniprot id: A0LLR9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ApbE family.
messages: Cell inner membrane
messages: Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.
messages: Heterodimer of a large and a small subunit.
messages: Magnesium. Can also use manganese.

335543:SFUM RS11495
gene id: 335543:SFUM_RS11495
uniprot id: A0LKF0
names: Similarity
messages: Belongs to the peptidase A31 family.

335543:SFUM RS01060
gene id: 335543:SFUM_RS01060
uniprot id: A0LEQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

335543:SFUM RS07080
gene id: 335543:SFUM_RS07080
uniprot id: A0LHZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

335543:SFUM RS06790
gene id: 335543:SFUM_RS06790
uniprot id: A0LHU3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

335543:SFUM RS20085
gene id: 335543:SFUM_RS20085
uniprot id: A0LQ58
names: Function
names: Similarity
names: Subunit
messages: Belongs to the desulfoferrodoxin family.
messages: Catalyzes the one-electron reduction of superoxide anion radical to hydrogen peroxide at a nonheme ferrous iron center. Plays a fundamental role in case of oxidative stress via its superoxide detoxification activity.
messages: Homodimer.

335543:SFUM RS01785
gene id: 335543:SFUM_RS01785
uniprot id: A0LF48
names: Similarity
messages: Belongs to the ros/MucR family.

335543:SFUM RS11380
gene id: 335543:SFUM_RS11380
uniprot id: A0LKD0
names: Subcellular Location Annotation
messages: Cytoplasm

335543:SFUM RS08005
gene id: 335543:SFUM_RS08005
uniprot id: A0LII0
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

335543:SFUM RS15460
gene id: 335543:SFUM_RS15460
uniprot id: A0LMK4
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

335543:SFUM RS04635
gene id: 335543:SFUM_RS04635
uniprot id: A0LGN8
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

335543:SFUM RS08035
gene id: 335543:SFUM_RS08035
uniprot id: A0LII6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

335543:SFUM RS12400
gene id: 335543:SFUM_RS12400
uniprot id: A0LKX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Membrane

335543:SFUM RS20115
gene id: 335543:SFUM_RS20115
uniprot id: A0LQ64
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

335543:SFUM RS08055
gene id: 335543:SFUM_RS08055
uniprot id: A0LIJ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

335543:SFUM RS14060
gene id: 335543:SFUM_RS14060
uniprot id: A0LLT9
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

335543:SFUM RS04810
gene id: 335543:SFUM_RS04810
uniprot id: A0LGS1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

335543:SFUM RS01175
gene id: 335543:SFUM_RS01175
uniprot id: A0LES7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell inner membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

335543:SFUM RS10770
gene id: 335543:SFUM_RS10770
uniprot id: A0LK12
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

335543:SFUM RS11570
gene id: 335543:SFUM_RS11570
uniprot id: A0LKG5
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

335543:SFUM RS06185
gene id: 335543:SFUM_RS06185
uniprot id: A0LHH6
names: Caution
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

335543:SFUM RS11180
gene id: 335543:SFUM_RS11180
uniprot id: A0LK92
names: Subcellular Location Annotation
messages: Membrane

335543:SFUM RS18955
gene id: 335543:SFUM_RS18955
uniprot id: A0LPI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

335543:SFUM RS18365
gene id: 335543:SFUM_RS18365
uniprot id: A0LP74
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.

335543:SFUM RS06290
gene id: 335543:SFUM_RS06290
uniprot id: A0LHJ7
names: Similarity
messages: Belongs to the Nudix hydrolase family.

335543:SFUM RS15925
gene id: 335543:SFUM_RS15925
uniprot id: A0LMU8
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

335543:SFUM RS06025
gene id: 335543:SFUM_RS06025
uniprot id: A0LHE9
names: Similarity
messages: Belongs to the universal stress protein A family.

335543:SFUM RS14570
gene id: 335543:SFUM_RS14570
uniprot id: A0LM35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

335543:SFUM RS16020
gene id: 335543:SFUM_RS16020
uniprot id: A0LMW8
names: Similarity
messages: Belongs to the GPAT/DAPAT family.

335543:SFUM RS15720
gene id: 335543:SFUM_RS15720
uniprot id: A0LML4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

335543:SFUM RS03925
gene id: 335543:SFUM_RS03925
uniprot id: A0LG99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

335543:SFUM RS00340
gene id: 335543:SFUM_RS00340
uniprot id: A0LEB5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

335543:SFUM RS20135
gene id: 335543:SFUM_RS20135
uniprot id: A0LQ68
names: Similarity
messages: Belongs to the ABC transporter superfamily.

335543:SFUM RS13035
gene id: 335543:SFUM_RS13035
uniprot id: A0LL98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

335543:SFUM RS14350
gene id: 335543:SFUM_RS14350
uniprot id: A0LLZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

335543:SFUM RS03515
gene id: 335543:SFUM_RS03515
uniprot id: A0LG30
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

335543:SFUM RS00300
gene id: 335543:SFUM_RS00300
uniprot id: A0LEA7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

335543:SFUM RS19370
gene id: 335543:SFUM_RS19370
uniprot id: A0LPR3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamA family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

335543:SFUM RS08250
gene id: 335543:SFUM_RS08250
uniprot id: A0LIN1
names: Domain
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

335543:SFUM RS00135
gene id: 335543:SFUM_RS00135
uniprot id: A0LE73
names: Similarity
messages: Belongs to the UPF0045 family.

335543:SFUM RS18600
gene id: 335543:SFUM_RS18600
uniprot id: A0LPB9
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

335543:SFUM RS15490
gene id: 335543:SFUM_RS15490
uniprot id: A0LML0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 2 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

335543:SFUM RS10930
gene id: 335543:SFUM_RS10930
uniprot id: A0LK44
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

335543:SFUM RS13735
gene id: 335543:SFUM_RS13735
uniprot id: A0LLM4
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

335543:SFUM RS07560
gene id: 335543:SFUM_RS07560
uniprot id: A0LI96
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

335543:SFUM RS23535
gene id: 335543:SFUM_RS23535
uniprot id: A0LJR7
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

335543:SFUM RS12465
gene id: 335543:SFUM_RS12465
uniprot id: A0LKY9
names: Similarity
messages: Belongs to the BPG-independent phosphoglycerate mutase family.

335543:SFUM RS10950
gene id: 335543:SFUM_RS10950
uniprot id: A0LK48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

335543:SFUM RS20325
gene id: 335543:SFUM_RS20325
uniprot id: A0LQA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

335543:SFUM RS18695
gene id: 335543:SFUM_RS18695
uniprot id: A0LPD7
names: Function
messages: Catalyzes the synthesis of GMP from XMP.

335543:SFUM RS12420
gene id: 335543:SFUM_RS12420
uniprot id: A0LKX9
names: Subcellular Location Annotation
messages: Membrane

335543:SFUM RS05540
gene id: 335543:SFUM_RS05540
uniprot id: A0LH56
names: Function
names: Similarity
messages: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
messages: Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines.

335543:SFUM RS20560
gene id: 335543:SFUM_RS20560
uniprot id: A0LQF8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DcuA/DcuB transporter (TC 2.A.13.1) family.
messages: Cell inner membrane
messages: Membrane
messages: Responsible for the transport of C4-dicarboxylates.

335543:SFUM RS01455
gene id: 335543:SFUM_RS01455
uniprot id: A0LEY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Membrane

335543:SFUM RS10675
gene id: 335543:SFUM_RS10675
uniprot id: A0LJZ3
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

335543:SFUM RS00630
gene id: 335543:SFUM_RS00630
uniprot id: A0LEG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

335543:SFUM RS18330
gene id: 335543:SFUM_RS18330
uniprot id: A0LP67
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

335543:SFUM RS18510
gene id: 335543:SFUM_RS18510
uniprot id: A0LPA2
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

335543:SFUM RS01805
gene id: 335543:SFUM_RS01805
uniprot id: A0LF52
names: Cofactor
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

335543:SFUM RS14590
gene id: 335543:SFUM_RS14590
uniprot id: A0LM40
names: Subcellular Location Annotation
messages: Membrane

335543:SFUM RS17900
gene id: 335543:SFUM_RS17900
uniprot id: A0LNY5
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

335543:SFUM RS12885
gene id: 335543:SFUM_RS12885
uniprot id: A0LL71
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

335543:SFUM RS09775
gene id: 335543:SFUM_RS09775
uniprot id: A0LJH5
names: Similarity
messages: Belongs to the peptidase C40 family.

335543:SFUM RS11715
gene id: 335543:SFUM_RS11715
uniprot id: A0LKJ3
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

335543:SFUM RS01045
gene id: 335543:SFUM_RS01045
uniprot id: A0LEQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

335543:SFUM RS10565
gene id: 335543:SFUM_RS10565
uniprot id: A0LJX1
names: Subcellular Location Annotation
messages: Membrane

335543:SFUM RS17070
gene id: 335543:SFUM_RS17070
uniprot id: A0LNH4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

335543:SFUM RS05120
gene id: 335543:SFUM_RS05120
uniprot id: A0LGX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Periplasm

335543:SFUM RS02205
gene id: 335543:SFUM_RS02205
uniprot id: A0LFC9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MntP (TC 9.B.29) family.
messages: Cell inner membrane
messages: Probably functions as a manganese efflux pump.

335543:SFUM RS17745
gene id: 335543:SFUM_RS17745
uniprot id: A0LNV7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

335543:SFUM RS20250
gene id: 335543:SFUM_RS20250
uniprot id: A0LQ92
names: Subcellular Location Annotation
messages: Membrane

335543:SFUM RS20240
gene id: 335543:SFUM_RS20240
uniprot id: A0LQ90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

335543:SFUM RS17845
gene id: 335543:SFUM_RS17845
uniprot id: A0LNX4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the adenylate cyclase family. DacA/CdaA subfamily.
messages: Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably a homodimer.

335543:SFUM RS12695
gene id: 335543:SFUM_RS12695
uniprot id: A0LL34
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.

335543:SFUM RS08725
gene id: 335543:SFUM_RS08725
uniprot id: A0LIX2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.

335543:SFUM RS01065
gene id: 335543:SFUM_RS01065
uniprot id: A0LEQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

335543:SFUM RS23390
gene id: 335543:SFUM_RS23390
uniprot id: A0LNC6
names: Subcellular Location Annotation
messages: Membrane

335543:SFUM RS15345
gene id: 335543:SFUM_RS15345
uniprot id: A0LMI1
names: Similarity
messages: Belongs to the pyruvate kinase family.

335543:SFUM RS20395
gene id: 335543:SFUM_RS20395
uniprot id: A0LQC2
names: Subcellular Location Annotation
messages: Periplasm

335543:SFUM RS13965
gene id: 335543:SFUM_RS13965
uniprot id: A0LLS0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.
messages: Binds 3 [4Fe-4S] clusters.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

335543:SFUM RS11565
gene id: 335543:SFUM_RS11565
uniprot id: A0LKG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

335543:SFUM RS10530
gene id: 335543:SFUM_RS10530
uniprot id: A0LJW5
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aquaporins contain two tandem repeats each containing three membrane-spanning domains and a pore-forming loop with the signature motif Asn-Pro-Ala (NPA).
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Cell inner membrane
messages: Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

335543:SFUM RS02190
gene id: 335543:SFUM_RS02190
uniprot id: A0LFC6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

335543:SFUM RS00330
gene id: 335543:SFUM_RS00330
uniprot id: A0LEB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

335543:SFUM RS18115
gene id: 335543:SFUM_RS18115
uniprot id: A0LP27
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).

335543:SFUM RS20290
gene id: 335543:SFUM_RS20290
uniprot id: A0LHF4
names: Function
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase family.
messages: CoA transferase having broad substrate specificity for short-chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons.

335543:SFUM RS11130
gene id: 335543:SFUM_RS11130
uniprot id: A0LK81
names: Cofactor
messages: Binds 1 [2Fe-2S] cluster per subunit.

335543:SFUM RS19915
gene id: 335543:SFUM_RS19915
uniprot id: A0LQ21
names: Function
names: Similarity
messages: Belongs to the vsr family.
messages: May nick specific sequences that contain T:G mispairs resulting from m5C-deamination.

335543:SFUM RS05295
gene id: 335543:SFUM_RS05295
uniprot id: A0LH11
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the NifH/BchL/ChlL family.
messages: Binds 1 [4Fe-4S] cluster per dimer.
messages: Homodimer.
messages: The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein.
messages: The reversible ADP-ribosylation of Arg-97 inactivates the nitrogenase reductase and regulates nitrogenase activity.

335543:SFUM RS17350
gene id: 335543:SFUM_RS17350
uniprot id: A0LNN1
names: Similarity
messages: Belongs to the polysaccharide synthase family.

335543:SFUM RS01000
gene id: 335543:SFUM_RS01000
uniprot id: A0LEP2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

335543:SFUM RS20975
gene id: 335543:SFUM_RS20975
uniprot id: A0LQN3
names: Subcellular Location Annotation
messages: Membrane

335543:SFUM RS07175
gene id: 335543:SFUM_RS07175
uniprot id: A0LI19
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

335543:SFUM RS21720
gene id: 335543:SFUM_RS21720
uniprot id: A0LJN7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the complex I 75 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

335543:SFUM RS09485
gene id: 335543:SFUM_RS09485
uniprot id: A0LJB9
names: Similarity
messages: Belongs to the ACC deaminase/D-cysteine desulfhydrase family.

335543:SFUM RS19375
gene id: 335543:SFUM_RS19375
uniprot id: A0LPR4
names: Similarity
messages: Belongs to the Skp family.

335543:SFUM RS19405
gene id: 335543:SFUM_RS19405
uniprot id: A0LPR9
names: Function
names: Similarity
messages: Belongs to the LpxB family.
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

335543:SFUM RS02450
gene id: 335543:SFUM_RS02450
uniprot id: A0LFH6
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

335543:SFUM RS02570
gene id: 335543:SFUM_RS02570
uniprot id: A0LFJ8
names: Similarity
messages: Belongs to the NDK family.

335543:SFUM RS13330
gene id: 335543:SFUM_RS13330
uniprot id: A0LLF0
names: Subcellular Location Annotation
messages: Membrane

335543:SFUM RS12880
gene id: 335543:SFUM_RS12880
uniprot id: A0LL70
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell inner membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

335543:SFUM RS03595
gene id: 335543:SFUM_RS03595
uniprot id: A0LG43
names: Subcellular Location Annotation
messages: Membrane

335543:SFUM RS17935
gene id: 335543:SFUM_RS17935
uniprot id: A0LNZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell inner membrane
messages: Self-interacts. Interacts with FtsZ.

335543:SFUM RS17080
gene id: 335543:SFUM_RS17080
uniprot id: A0LNH6
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

335543:SFUM RS03085
gene id: 335543:SFUM_RS03085
uniprot id: A0LFU6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

335543:SFUM RS00560
gene id: 335543:SFUM_RS00560
uniprot id: A0LEF5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

335543:SFUM RS11850
gene id: 335543:SFUM_RS11850
uniprot id: A0LKM1
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

335543:SFUM RS12135
gene id: 335543:SFUM_RS12135
uniprot id: A0LKS4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

335543:SFUM RS21640
gene id: 335543:SFUM_RS21640
uniprot id: A0LIR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

335543:SFUM RS13530
gene id: 335543:SFUM_RS13530
uniprot id: A0LLI5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell inner membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.

335543:SFUM RS10015
gene id: 335543:SFUM_RS10015
uniprot id: A0LJM1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

335543:SFUM RS12290
gene id: 335543:SFUM_RS12290
uniprot id: A0LKV5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urocanase family.
messages: Binds 1 NAD(+) per subunit.
messages: Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

335543:SFUM RS06435
gene id: 335543:SFUM_RS06435
uniprot id: A0LHM4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

335543:SFUM RS20185
gene id: 335543:SFUM_RS20185
uniprot id: A0LQ79
names: Similarity
messages: Belongs to the alpha-acetolactate decarboxylase family.

335543:SFUM RS02825
gene id: 335543:SFUM_RS02825
uniprot id: A0LFP5
names: Similarity
messages: Belongs to the peptidase S66 family.

335543:SFUM RS15445
gene id: 335543:SFUM_RS15445
uniprot id: A0LMK1
names: Subunit
messages: Homodimer.

335543:SFUM RS07420
gene id: 335543:SFUM_RS07420
uniprot id: A0LI69
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

335543:SFUM RS17820
gene id: 335543:SFUM_RS17820
uniprot id: A0LNX0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

335543:SFUM RS07760
gene id: 335543:SFUM_RS07760
uniprot id: A0LID6
names: Subcellular Location Annotation
messages: Membrane

335543:SFUM RS17650
gene id: 335543:SFUM_RS17650
uniprot id: A0LNT8
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

335543:SFUM RS03400
gene id: 335543:SFUM_RS03400
uniprot id: A0LG08
names: Similarity
messages: Belongs to the creatininase superfamily.

335543:SFUM RS13705
gene id: 335543:SFUM_RS13705
uniprot id: A0LLL8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

335543:SFUM RS10020
gene id: 335543:SFUM_RS10020
uniprot id: A0LJM2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

335543:SFUM RS07380
gene id: 335543:SFUM_RS07380
uniprot id: A0LI61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

335543:SFUM RS17925
gene id: 335543:SFUM_RS17925
uniprot id: A0LNZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

335543:SFUM RS20680
gene id: 335543:SFUM_RS20680
uniprot id: A0LQH7
names: Function
names: Similarity
messages: Belongs to the carbamoyltransferase HypF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases. HypF functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide.

335543:SFUM RS08080
gene id: 335543:SFUM_RS08080
uniprot id: A0LIJ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity).

335543:SFUM RS20835
gene id: 335543:SFUM_RS20835
uniprot id: A0LQK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsrC/TusE family.
messages: Cytoplasm

335543:SFUM RS00180
gene id: 335543:SFUM_RS00180
uniprot id: A0LE83
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

335543:SFUM RS15535
gene id: 335543:SFUM_RS15535
uniprot id: A0LML9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

335543:SFUM RS14025
gene id: 335543:SFUM_RS14025
uniprot id: A0LLT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FNT transporter (TC 2.A.44) family.
messages: Membrane

335543:SFUM RS02915
gene id: 335543:SFUM_RS02915
uniprot id: A0LFR2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

335543:SFUM RS14455
gene id: 335543:SFUM_RS14455
uniprot id: A0LM14
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

335543:SFUM RS02685
gene id: 335543:SFUM_RS02685
uniprot id: A0LFM0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

335543:SFUM RS07010
gene id: 335543:SFUM_RS07010
uniprot id: A0LHY6
names: Similarity
messages: Belongs to the CRISPR-associated Csm3 family.

335543:SFUM RS07970
gene id: 335543:SFUM_RS07970
uniprot id: A0LIH4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

335543:SFUM RS01830
gene id: 335543:SFUM_RS01830
uniprot id: A0LF57
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.

335543:SFUM RS04925
gene id: 335543:SFUM_RS04925
uniprot id: A0LGU2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

335543:SFUM RS15475
gene id: 335543:SFUM_RS15475
uniprot id: A0LMK7
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain.

335543:SFUM RS15915
gene id: 335543:SFUM_RS15915
uniprot id: A0LMU6
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

335543:SFUM RS11940
gene id: 335543:SFUM_RS11940
uniprot id: A0LKN9
names: Subcellular Location Annotation
messages: Membrane

335543:SFUM RS12170
gene id: 335543:SFUM_RS12170
uniprot id: A0LKT1
names: Subcellular Location Annotation
messages: Membrane

335543:SFUM RS15955
gene id: 335543:SFUM_RS15955
uniprot id: A0LMV5
names: Caution
names: Function
names: Similarity
messages: Belongs to the UbiX/PAD1 family.
messages: Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

335543:SFUM RS08760
gene id: 335543:SFUM_RS08760
uniprot id: A0LIY0
names: Similarity
messages: Belongs to the GSP E family.

335543:SFUM RS02845
gene id: 335543:SFUM_RS02845
uniprot id: A0LFP9
names: Subcellular Location Annotation
messages: Membrane

335543:SFUM RS16115
gene id: 335543:SFUM_RS16115
uniprot id: A0LMY7
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

335543:SFUM RS07935
gene id: 335543:SFUM_RS07935
uniprot id: A0LIG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

335543:SFUM RS15305
gene id: 335543:SFUM_RS15305
uniprot id: A0LMH3
names: Similarity
messages: Belongs to the peptidase A31 family.

335543:SFUM RS15655
gene id: 335543:SFUM_RS15655
uniprot id: A0LMK1
names: Subunit
messages: Homodimer.

335543:SFUM RS15525
gene id: 335543:SFUM_RS15525
uniprot id: A0LML7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-insensitive subfamily.
messages: Cell inner membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force.

335543:SFUM RS17115
gene id: 335543:SFUM_RS17115
uniprot id: A0LNI3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

335543:SFUM RS03980
gene id: 335543:SFUM_RS03980
uniprot id: A0LGB0
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

335543:SFUM RS03920
gene id: 335543:SFUM_RS03920
uniprot id: A0LG98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

335543:SFUM RS15895
gene id: 335543:SFUM_RS15895
uniprot id: A0LMU1
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

335543:SFUM RS05635
gene id: 335543:SFUM_RS05635
uniprot id: A0LH76
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

335543:SFUM RS18775
gene id: 335543:SFUM_RS18775
uniprot id: A0LPE8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

335543:SFUM RS21460
gene id: 335543:SFUM_RS21460
uniprot id: A0LH74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

335543:SFUM RS22135
gene id: 335543:SFUM_RS22135
uniprot id: A0LPI6
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT.

335543:SFUM RS03050
gene id: 335543:SFUM_RS03050
uniprot id: A0LFU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

335543:SFUM RS00895
gene id: 335543:SFUM_RS00895
uniprot id: A0LEM2
names: Similarity
messages: Belongs to the PrpD family.

335543:SFUM RS11050
gene id: 335543:SFUM_RS11050
uniprot id: A0LK65
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

335543:SFUM RS14300
gene id: 335543:SFUM_RS14300
uniprot id: A0LLY5
names: Similarity
messages: Belongs to the GARS family.

335543:SFUM RS14180
gene id: 335543:SFUM_RS14180
uniprot id: A0LLW3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

335543:SFUM RS20995
gene id: 335543:SFUM_RS20995
uniprot id: A0LQN7
names: Function
names: Similarity
messages: Belongs to the phenylacetyl-CoA ligase family.
messages: Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).

335543:SFUM RS06250
gene id: 335543:SFUM_RS06250
uniprot id: A0LHI9
names: Function
names: Similarity
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

335543:SFUM RS11710
gene id: 335543:SFUM_RS11710
uniprot id: A0LKJ2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

335543:SFUM RS12355
gene id: 335543:SFUM_RS12355
uniprot id: A0LKW7
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT.

335543:SFUM RS08460
gene id: 335543:SFUM_RS08460
uniprot id: A0LIR9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

335543:SFUM RS10035
gene id: 335543:SFUM_RS10035
uniprot id: A0LJM4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

335543:SFUM RS03745
gene id: 335543:SFUM_RS03745
uniprot id: A0LG67
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

335543:SFUM RS15210
gene id: 335543:SFUM_RS15210
uniprot id: A0LMF6
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

335543:SFUM RS06615
gene id: 335543:SFUM_RS06615
uniprot id: A0LHQ7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

335543:SFUM RS02290
gene id: 335543:SFUM_RS02290
uniprot id: A0LFE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

335543:SFUM RS01105
gene id: 335543:SFUM_RS01105
uniprot id: A0LER3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Plays an essential role in type IV pili and type II pseudopili formation by proteolytically removing the leader sequence from substrate proteins and subsequently monomethylating the alpha-amino group of the newly exposed N-terminal phenylalanine.

335543:SFUM RS20775
gene id: 335543:SFUM_RS20775
uniprot id: A0LQJ7
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

335543:SFUM RS18755
gene id: 335543:SFUM_RS18755
uniprot id: A0LPE4
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.

335543:SFUM RS20805
gene id: 335543:SFUM_RS20805
uniprot id: A0LQK3
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

335543:SFUM RS19510
gene id: 335543:SFUM_RS19510
uniprot id: A0LPU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

335543:SFUM RS22110
gene id: 335543:SFUM_RS22110
uniprot id: A0LPD0
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

335543:SFUM RS20710
gene id: 335543:SFUM_RS20710
uniprot id: A0LQI3
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

335543:SFUM RS00765
gene id: 335543:SFUM_RS00765
uniprot id: A0LEJ7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

335543:SFUM RS16980
gene id: 335543:SFUM_RS16980
uniprot id: A0LNF6
names: Similarity
messages: Belongs to the fabD family.

335543:SFUM RS07515
gene id: 335543:SFUM_RS07515
uniprot id: A0LI87
names: Subcellular Location Annotation
messages: Cytoplasm

335543:SFUM RS18255
gene id: 335543:SFUM_RS18255
uniprot id: A0LP54
names: Subcellular Location Annotation
messages: Periplasm

335543:SFUM RS18850
gene id: 335543:SFUM_RS18850
uniprot id: A0LPG3
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

335543:SFUM RS03715
gene id: 335543:SFUM_RS03715
uniprot id: A0LG61
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

335543:SFUM RS12610
gene id: 335543:SFUM_RS12610
uniprot id: A0LL16
names: Similarity
messages: Belongs to the class-II fumarase/aspartase family. Aspartase subfamily.

335543:SFUM RS08070
gene id: 335543:SFUM_RS08070
uniprot id: A0LIJ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

335543:SFUM RS03455
gene id: 335543:SFUM_RS03455
uniprot id: A0LG20
names: Similarity
messages: Belongs to the glycosyl hydrolase 63 family.

335543:SFUM RS00680
gene id: 335543:SFUM_RS00680
uniprot id: A0LEH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

335543:SFUM RS21020
gene id: 335543:SFUM_RS21020
uniprot id: A0LQP2
names: Similarity
messages: Belongs to the AOR/FOR family.

335543:SFUM RS11785
gene id: 335543:SFUM_RS11785
uniprot id: A0LKL0
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

335543:SFUM RS10115
gene id: 335543:SFUM_RS10115
uniprot id: A0LJN8
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

335543:SFUM RS10270
gene id: 335543:SFUM_RS10270
uniprot id: A0LJR5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

335543:SFUM RS12785
gene id: 335543:SFUM_RS12785
uniprot id: A0LL53
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

335543:SFUM RS08825
gene id: 335543:SFUM_RS08825
uniprot id: A0LIZ3
names: Similarity
messages: Belongs to the thioredoxin family.

335543:SFUM RS07730
gene id: 335543:SFUM_RS07730
uniprot id: A0LID0
names: Similarity
messages: Belongs to the bacterial secretin family.

335543:SFUM RS09405
gene id: 335543:SFUM_RS09405
uniprot id: A0LJA4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

335543:SFUM RS12855
gene id: 335543:SFUM_RS12855
uniprot id: A0LL65
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

335543:SFUM RS13725
gene id: 335543:SFUM_RS13725
uniprot id: A0LLM2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Forms a 24-polypeptide structural core with octahedral symmetry.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

335543:SFUM RS15335
gene id: 335543:SFUM_RS15335
uniprot id: A0LMH9
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

335543:SFUM RS07650
gene id: 335543:SFUM_RS07650
uniprot id: A0LIB3
names: Similarity
messages: Belongs to the AAE transporter (TC 2.A.81) family.

335543:SFUM RS08075
gene id: 335543:SFUM_RS08075
uniprot id: A0LIJ4
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

335543:SFUM RS05405
gene id: 335543:SFUM_RS05405
uniprot id: A0LH31
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Cob(I)alamin adenosyltransferase family.
messages: Cytoplasm
messages: Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids.

335543:SFUM RS10180
gene id: 335543:SFUM_RS10180
uniprot id: A0LJQ0
names: Similarity
messages: Belongs to the UPF0047 family.

335543:SFUM RS06395
gene id: 335543:SFUM_RS06395
uniprot id: A0LHL6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

335543:SFUM RS10150
gene id: 335543:SFUM_RS10150
uniprot id: A0LJP5
names: Similarity
messages: Belongs to the peptidase S49 family.

335543:SFUM RS10955
gene id: 335543:SFUM_RS10955
uniprot id: A0LK49
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS1 family.

335543:SFUM RS15450
gene id: 335543:SFUM_RS15450
uniprot id: A0LMK2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

335543:SFUM RS13930
gene id: 335543:SFUM_RS13930
uniprot id: A0LLR3
names: Similarity
messages: Belongs to the formate--tetrahydrofolate ligase family.

335543:SFUM RS09970
gene id: 335543:SFUM_RS09970
uniprot id: A0LJL3
names: Similarity
messages: Belongs to the threonine synthase family.

335543:SFUM RS04645
gene id: 335543:SFUM_RS04645
uniprot id: A0LGP0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

335543:SFUM RS09195
gene id: 335543:SFUM_RS09195
uniprot id: A0LJ64
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

335543:SFUM RS15030
gene id: 335543:SFUM_RS15030
uniprot id: A0LMC0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily.
messages: Homodimer.
messages: Involved in phosphonate degradation.

335543:SFUM RS06580
gene id: 335543:SFUM_RS06580
uniprot id: A0LHQ0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

335543:SFUM RS15500
gene id: 335543:SFUM_RS15500
uniprot id: A0LML2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

335543:SFUM RS07300
gene id: 335543:SFUM_RS07300
uniprot id: A0LI45
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

335543:SFUM RS03775
gene id: 335543:SFUM_RS03775
uniprot id: A0LG72
names: Similarity
messages: Belongs to the P(II) protein family.

335543:SFUM RS07485
gene id: 335543:SFUM_RS07485
uniprot id: A0LI80
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

335543:SFUM RS13715
gene id: 335543:SFUM_RS13715
uniprot id: A0LLM0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

335543:SFUM RS18500
gene id: 335543:SFUM_RS18500
uniprot id: A0LPA0
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

335543:SFUM RS10430
gene id: 335543:SFUM_RS10430
uniprot id: A0LJU6
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

335543:SFUM RS02470
gene id: 335543:SFUM_RS02470
uniprot id: A0LFH9
names: Similarity
messages: Belongs to the phosphohexose mutase family.

335543:SFUM RS01185
gene id: 335543:SFUM_RS01185
uniprot id: A0LES9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0073 (Hly-III) family.
messages: Membrane

335543:SFUM RS15870
gene id: 335543:SFUM_RS15870
uniprot id: A0LMT6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell inner membrane
messages: Part of the ABC transporter FtsEX involved in cellular division.

335543:SFUM RS07085
gene id: 335543:SFUM_RS07085
uniprot id: A0LI00
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell inner membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

335543:SFUM RS12335
gene id: 335543:SFUM_RS12335
uniprot id: A0LKW3
names: Subcellular Location Annotation
messages: Membrane

335543:SFUM RS01570
gene id: 335543:SFUM_RS01570
uniprot id: A0LF07
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

335543:SFUM RS10355
gene id: 335543:SFUM_RS10355
uniprot id: A0LJT1
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: The fumarate reductase enzyme complex is required for fumarate respiration. This subunit anchors the complex in the membrane and binds a diheme cytochrome b.

335543:SFUM RS04010
gene id: 335543:SFUM_RS04010
uniprot id: A0LGB7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

335543:SFUM RS08945
gene id: 335543:SFUM_RS08945
uniprot id: A0LJ16
names: Caution
names: Similarity
messages: Arg-61 is present instead of the conserved Lys which is expected to be an active site residue. The same site-directed mutant in B.cereus has no activity; therefore this protein is probably inactive.
messages: Belongs to the HAD-like hydrolase superfamily. PhnX family.

335543:SFUM RS14880
gene id: 335543:SFUM_RS14880
uniprot id: A0LM93
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

335543:SFUM RS14985
gene id: 335543:SFUM_RS14985
uniprot id: A0LMB1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PstS family.
messages: Involved in the system for phosphate transport across the cytoplasmic membrane.
messages: Periplasm
messages: Secreted

335543:SFUM RS00325
gene id: 335543:SFUM_RS00325
uniprot id: A0LEB2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.

335543:SFUM RS03235
gene id: 335543:SFUM_RS03235
uniprot id: A0LFX7
names: Function
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

335543:SFUM RS08180
gene id: 335543:SFUM_RS08180
uniprot id: A0LIL6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

335543:SFUM RS17955
gene id: 335543:SFUM_RS17955
uniprot id: A0LNZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SelA family.
messages: Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
messages: Cytoplasm

335543:SFUM RS00275
gene id: 335543:SFUM_RS00275
uniprot id: A0LEA2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 3B subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

335543:SFUM RS04720
gene id: 335543:SFUM_RS04720
uniprot id: A0LGQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

335543:SFUM RS19500
gene id: 335543:SFUM_RS19500
uniprot id: A0LPT8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RdgC family.
messages: May be involved in recombination.
messages: nucleoid

335543:SFUM RS10135
gene id: 335543:SFUM_RS10135
uniprot id: A0LJP2
names: Subunit
messages: Heterodimer of a large and a small subunit.

335543:SFUM RS07120
gene id: 335543:SFUM_RS07120
uniprot id: A0LI08
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

335543:SFUM RS18370
gene id: 335543:SFUM_RS18370
uniprot id: A0LP75
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 2 residues (Tyr-72 and Arg-75) present in a large hydrophobic pocket are probably involved in substrate specificity. They are important for desuccinylation activity, but dispensable for deacetylation activity.
messages: Belongs to the sirtuin family. Class III subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form.

335543:SFUM RS02060
gene id: 335543:SFUM_RS02060
uniprot id: A0LFA3
names: Similarity
messages: Belongs to the histone deacetylase family.

335543:SFUM RS05385
gene id: 335543:SFUM_RS05385
uniprot id: A0LH28
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

335543:SFUM RS19010
gene id: 335543:SFUM_RS19010
uniprot id: A0LPJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

335543:SFUM RS07545
gene id: 335543:SFUM_RS07545
uniprot id: A0LI93
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

335543:SFUM RS09155
gene id: 335543:SFUM_RS09155
uniprot id: A0LJ56
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

335543:SFUM RS04240
gene id: 335543:SFUM_RS04240
uniprot id: A0LGG2
names: Similarity
messages: Belongs to the ABC transporter superfamily.

335543:SFUM RS20150
gene id: 335543:SFUM_RS20150
uniprot id: A0LQ71
names: Similarity
messages: Belongs to the RutC family.

335543:SFUM RS10830
gene id: 335543:SFUM_RS10830
uniprot id: A0LK24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

335543:SFUM RS11020
gene id: 335543:SFUM_RS11020
uniprot id: A0LK59
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

335543:SFUM RS05705
gene id: 335543:SFUM_RS05705
uniprot id: A0LH88
names: Similarity
messages: Belongs to the UPF0178 family.

335543:SFUM RS01200
gene id: 335543:SFUM_RS01200
uniprot id: A0LET3
names: Similarity
messages: Belongs to the ros/MucR family.

335543:SFUM RS20555
gene id: 335543:SFUM_RS20555
uniprot id: A0LQF7
names: Subcellular Location Annotation
messages: Cytoplasm

335543:SFUM RS06595
gene id: 335543:SFUM_RS06595
uniprot id: A0LHQ3
names: Similarity
messages: Belongs to the SAICAR synthetase family.

335543:SFUM RS19055
gene id: 335543:SFUM_RS19055
uniprot id: A0LPK4
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

335543:SFUM RS00060
gene id: 335543:SFUM_RS00060
uniprot id: A0LE62
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

335543:SFUM RS07645
gene id: 335543:SFUM_RS07645
uniprot id: A0LIB2
names: Similarity
messages: Belongs to the pyruvate kinase family.

335543:SFUM RS08025
gene id: 335543:SFUM_RS08025
uniprot id: A0LII4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

335543:SFUM RS06940
gene id: 335543:SFUM_RS06940
uniprot id: A0LHX2
names: Similarity
messages: Belongs to the CFA/CMAS family.

335543:SFUM RS17920
gene id: 335543:SFUM_RS17920
uniprot id: A0LNY9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

335543:SFUM RS15470
gene id: 335543:SFUM_RS15470
uniprot id: A0LMK6
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

335543:SFUM RS07335
gene id: 335543:SFUM_RS07335
uniprot id: A0LI52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

335543:SFUM RS13415
gene id: 335543:SFUM_RS13415
uniprot id: A0LLG2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell inner membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.

335543:SFUM RS01460
gene id: 335543:SFUM_RS01460
uniprot id: A0LEY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

335543:SFUM RS09420
gene id: 335543:SFUM_RS09420
uniprot id: A0LJA7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).

335543:SFUM RS02000
gene id: 335543:SFUM_RS02000
uniprot id: A0LF91
names: Cofactor
names: Function
messages: Binds 2 [4Fe-4S] clusters.
messages: Component of a complex that catalyzes the oxidation of glycolate to glyoxylate.

335543:SFUM RS07855
gene id: 335543:SFUM_RS07855
uniprot id: A0LIF0
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: May be specifically involved in the processing, transport, and/or maturation of the MADH beta-subunit.
messages: Membrane

335543:SFUM RS10420
gene id: 335543:SFUM_RS10420
uniprot id: A0LJU4
names: Subcellular Location Annotation
messages: Membrane

335543:SFUM RS12900
gene id: 335543:SFUM_RS12900
uniprot id: A0LL74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

335543:SFUM RS00290
gene id: 335543:SFUM_RS00290
uniprot id: A0LEA5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. LL-diaminopimelate aminotransferase subfamily.
messages: Homodimer.
messages: Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate. Can also use m-DAP instead of LL-DAP as the amino-group donor.

335543:SFUM RS13515
gene id: 335543:SFUM_RS13515
uniprot id: A0LLI2
names: Function
names: Similarity
messages: Belongs to the ParB family.
messages: Involved in chromosome partition. Localize to both poles of the predivisional cell following completion of DNA replication. Binds to the DNA origin of replication.

335543:SFUM RS01345
gene id: 335543:SFUM_RS01345
uniprot id: A0LEW2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

335543:SFUM RS00285
gene id: 335543:SFUM_RS00285
uniprot id: A0LEA4
names: Function
names: Similarity
messages: Belongs to the HPPK family.
messages: Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.

335543:SFUM RS13590
gene id: 335543:SFUM_RS13590
uniprot id: A0LLJ6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpA family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds the periplasmic potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

335543:SFUM RS17860
gene id: 335543:SFUM_RS17860
uniprot id: A0LNX7
names: Similarity
messages: Belongs to the Nudix hydrolase family.

335543:SFUM RS10710
gene id: 335543:SFUM_RS10710
uniprot id: A0LK00
names: Function
names: Similarity
messages: Belongs to the sigma-54 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

335543:SFUM RS17890
gene id: 335543:SFUM_RS17890
uniprot id: A0LNY3
names: Subcellular Location Annotation
messages: Membrane

335543:SFUM RS06280
gene id: 335543:SFUM_RS06280
uniprot id: A0LHJ5
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.

335543:SFUM RS01725
gene id: 335543:SFUM_RS01725
uniprot id: A0LF36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

335543:SFUM RS15745
gene id: 335543:SFUM_RS15745
uniprot id: A0LML9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

335543:SFUM RS07630
gene id: 335543:SFUM_RS07630
uniprot id: A0LIA9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Homohexamer.
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the CobB/CobQ family.
messages: Involved in acetate metabolism.
messages: The N-terminal region seems to be important for proper quaternary structure. The C-terminal region contains the substrate-binding site.

335543:SFUM RS06295
gene id: 335543:SFUM_RS06295
uniprot id: A0LHJ8
names: Subcellular Location Annotation
messages: Membrane

335543:SFUM RS02960
gene id: 335543:SFUM_RS02960
uniprot id: A0LFS1
names: Activity Regulation
names: Caution
names: Domain
names: Function
names: Similarity
messages: Belongs to the GlnD family.
messages: Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism.
messages: Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity.

335543:SFUM RS16035
gene id: 335543:SFUM_RS16035
uniprot id: A0LMX1
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

335543:SFUM RS02480
gene id: 335543:SFUM_RS02480
uniprot id: A0LFI1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

335543:SFUM RS19060
gene id: 335543:SFUM_RS19060
uniprot id: A0LPK5
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

335543:SFUM RS15085
gene id: 335543:SFUM_RS15085
uniprot id: A0LMD1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

335543:SFUM RS00050
gene id: 335543:SFUM_RS00050
uniprot id: A0LE60
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

335543:SFUM RS17885
gene id: 335543:SFUM_RS17885
uniprot id: A0LNY2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

335543:SFUM RS03970
gene id: 335543:SFUM_RS03970
uniprot id: A0LGA8
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

335543:SFUM RS07155
gene id: 335543:SFUM_RS07155
uniprot id: A0LI15
names: Similarity
messages: Belongs to the LacAB/RpiB family.

335543:SFUM RS15750
gene id: 335543:SFUM_RS15750
uniprot id: A0LMM0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpB which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpB.

335543:SFUM RS15835
gene id: 335543:SFUM_RS15835
uniprot id: A0LMS9
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

335543:SFUM RS03885
gene id: 335543:SFUM_RS03885
uniprot id: A0LG91
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.

335543:SFUM RS15040
gene id: 335543:SFUM_RS15040
uniprot id: A0LMC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

335543:SFUM RS14845
gene id: 335543:SFUM_RS14845
uniprot id: A0LM85
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

335543:SFUM RS15700
gene id: 335543:SFUM_RS15700
uniprot id: A0LML0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 2 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

335543:SFUM RS15530
gene id: 335543:SFUM_RS15530
uniprot id: A0LML8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

335543:SFUM RS09325
gene id: 335543:SFUM_RS09325
uniprot id: A0LJ87
names: Similarity
messages: Belongs to the HdrA family.

335543:SFUM RS08680
gene id: 335543:SFUM_RS08680
uniprot id: A0LIW4
names: Subcellular Location Annotation
messages: Membrane

335543:SFUM RS16635
gene id: 335543:SFUM_RS16635
uniprot id: A0LN88
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

335543:SFUM RS03300
gene id: 335543:SFUM_RS03300
uniprot id: A0LFY8
names: Similarity
messages: Belongs to the universal stress protein A family.

335543:SFUM RS16200
gene id: 335543:SFUM_RS16200
uniprot id: A0LN04
names: Similarity
messages: Belongs to the HdrA family.

335543:SFUM RS10805
gene id: 335543:SFUM_RS10805
uniprot id: A0LK18
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

335543:SFUM RS14820
gene id: 335543:SFUM_RS14820
uniprot id: A0LM81
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

335543:SFUM RS02440
gene id: 335543:SFUM_RS02440
uniprot id: A0LFH4
names: Similarity
messages: Belongs to the YkuD family.

335543:SFUM RS10815
gene id: 335543:SFUM_RS10815
uniprot id: A0LK21
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

335543:SFUM RS08210
gene id: 335543:SFUM_RS08210
uniprot id: A0LIM1
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

335543:SFUM RS12905
gene id: 335543:SFUM_RS12905
uniprot id: A0LL75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

335543:SFUM RS08130
gene id: 335543:SFUM_RS08130
uniprot id: A0LIK6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

335543:SFUM RS23325
gene id: 335543:SFUM_RS23325
uniprot id: A0LK26
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

335543:SFUM RS04680
gene id: 335543:SFUM_RS04680
uniprot id: A0LGP8
names: Subcellular Location Annotation
messages: Membrane

335543:SFUM RS20915
gene id: 335543:SFUM_RS20915
uniprot id: A0LQM4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

335543:SFUM RS01505
gene id: 335543:SFUM_RS01505
uniprot id: A0LEZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

335543:SFUM RS13315
gene id: 335543:SFUM_RS13315
uniprot id: A0LLE7
names: Cofactor
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Binds 1 zinc ion per subunit. The zinc ion is important for the structural integrity of the protein.

335543:SFUM RS05255
gene id: 335543:SFUM_RS05255
uniprot id: A0LH03
names: Similarity
messages: Belongs to the radical SAM superfamily. NifB family.

335543:SFUM RS20235
gene id: 335543:SFUM_RS20235
uniprot id: A0LQ89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

335543:SFUM RS07280
gene id: 335543:SFUM_RS07280
uniprot id: A0LI41
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

335543:SFUM RS00145
gene id: 335543:SFUM_RS00145
uniprot id: A0LE75
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

335543:SFUM RS11900
gene id: 335543:SFUM_RS11900
uniprot id: A0LKN1
names: Similarity
messages: Belongs to the 4-oxalocrotonate tautomerase family.

335543:SFUM RS06110
gene id: 335543:SFUM_RS06110
uniprot id: A0LHG2
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

335543:SFUM RS05600
gene id: 335543:SFUM_RS05600
uniprot id: A0LH69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

335543:SFUM RS14075
gene id: 335543:SFUM_RS14075
uniprot id: A0LLU2
names: Similarity
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.

335543:SFUM RS19115
gene id: 335543:SFUM_RS19115
uniprot id: A0LPL6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

335543:SFUM RS18870
gene id: 335543:SFUM_RS18870
uniprot id: A0LPG7
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

335543:SFUM RS07555
gene id: 335543:SFUM_RS07555
uniprot id: A0LI95
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

335543:SFUM RS11630
gene id: 335543:SFUM_RS11630
uniprot id: A0LKH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

335543:SFUM RS13075
gene id: 335543:SFUM_RS13075
uniprot id: A0LLA6
names: Similarity
messages: Belongs to the CinA family.

335543:SFUM RS14625
gene id: 335543:SFUM_RS14625
uniprot id: A0LM47
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

335543:SFUM RS10005
gene id: 335543:SFUM_RS10005
uniprot id: A0LJL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

335543:SFUM RS05525
gene id: 335543:SFUM_RS05525
uniprot id: A0LH54
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

335543:SFUM RS17560
gene id: 335543:SFUM_RS17560
uniprot id: A0LNS2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the selenophosphate synthase 1 family. Class I subfamily.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Synthesizes selenophosphate from selenide and ATP.

335543:SFUM RS14105
gene id: 335543:SFUM_RS14105
uniprot id: A0LLU7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).

335543:SFUM RS00780
gene id: 335543:SFUM_RS00780
uniprot id: A0LEK0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.

335543:SFUM RS07135
gene id: 335543:SFUM_RS07135
uniprot id: A0LI11
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

335543:SFUM RS10735
gene id: 335543:SFUM_RS10735
uniprot id: A0LK05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

335543:SFUM RS16925
gene id: 335543:SFUM_RS16925
uniprot id: A0LNE5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

335543:SFUM RS21600
gene id: 335543:SFUM_RS21600
uniprot id: A0LIE3
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

335543:SFUM RS06100
gene id: 335543:SFUM_RS06100
uniprot id: A0LHG0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

335543:SFUM RS03875
gene id: 335543:SFUM_RS03875
uniprot id: A0LG90
names: Similarity
messages: Belongs to the phosphohexose mutase family.

335543:SFUM RS03665
gene id: 335543:SFUM_RS03665
uniprot id: A0LG51
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PstS family.
messages: Involved in the system for phosphate transport across the cytoplasmic membrane.
messages: Periplasm
messages: Secreted

335543:SFUM RS20510
gene id: 335543:SFUM_RS20510
uniprot id: A0LQE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the kinesin light chain family.
messages: cytoskeleton

335543:SFUM RS10875
gene id: 335543:SFUM_RS10875
uniprot id: A0LK33
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

335543:SFUM RS03255
gene id: 335543:SFUM_RS03255
uniprot id: A0LFY1
names: Function
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

335543:SFUM RS03240
gene id: 335543:SFUM_RS03240
uniprot id: A0LFX8
names: Subcellular Location Annotation
messages: Membrane

335543:SFUM RS18475
gene id: 335543:SFUM_RS18475
uniprot id: A0LP96
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

335543:SFUM RS05280
gene id: 335543:SFUM_RS05280
uniprot id: A0LH08
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NifD/NifK/NifE/NifN family.
messages: Tetramer of two alpha and two beta chains. Forms complex with the iron protein (nitrogenase component 2).
messages: This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation.

335543:SFUM RS14170
gene id: 335543:SFUM_RS14170
uniprot id: A0LLW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

335543:SFUM RS00535
gene id: 335543:SFUM_RS00535
uniprot id: A0LEF1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

335543:SFUM RS11450
gene id: 335543:SFUM_RS11450
uniprot id: A0LKE3
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily.

335543:SFUM RS14575
gene id: 335543:SFUM_RS14575
uniprot id: A0LM36
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Macrolide exporter (TC 3.A.1.122) family.
messages: Cell inner membrane
messages: Homodimer.
messages: Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.

335543:SFUM RS20180
gene id: 335543:SFUM_RS20180
uniprot id: A0LQ78
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

335543:SFUM RS08285
gene id: 335543:SFUM_RS08285
uniprot id: A0LIN8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transcriptional regulatory Rex family.
messages: Cytoplasm
messages: Homodimer.
messages: Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.

335543:SFUM RS09910
gene id: 335543:SFUM_RS09910
uniprot id: A0LJK2
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

335543:SFUM RS19085
gene id: 335543:SFUM_RS19085
uniprot id: A0LPL0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

335543:SFUM RS13080
gene id: 335543:SFUM_RS13080
uniprot id: A0LLA7
names: Similarity
messages: Belongs to the LarC family.

335543:SFUM RS10000
gene id: 335543:SFUM_RS10000
uniprot id: A0LJL8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

335543:SFUM RS02350
gene id: 335543:SFUM_RS02350
uniprot id: A0LFF7
names: Similarity
names: Subunit
messages: Belongs to the MoaE family.
messages: Heterotetramer of 2 MoaD subunits and 2 MoaE subunits. Also stable as homodimer. The enzyme changes between these two forms during catalysis.

335543:SFUM RS15360
gene id: 335543:SFUM_RS15360
uniprot id: A0LMI4
names: Function
names: Similarity
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.

335543:SFUM RS04865
gene id: 335543:SFUM_RS04865
uniprot id: A0LGT1
names: Domain
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

335543:SFUM RS08185
gene id: 335543:SFUM_RS08185
uniprot id: A0LIL7
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

335543:SFUM RS20685
gene id: 335543:SFUM_RS20685
uniprot id: A0LQH8
names: Similarity
messages: Belongs to the HypD family.

335543:SFUM RS04230
gene id: 335543:SFUM_RS04230
uniprot id: A0LGG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

335543:SFUM RS16185
gene id: 335543:SFUM_RS16185
uniprot id: A0LN01
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

335543:SFUM RS20960
gene id: 335543:SFUM_RS20960
uniprot id: A0LQN0
names: Similarity
messages: Belongs to the glutamate synthase family.

335543:SFUM RS13455
gene id: 335543:SFUM_RS13455
uniprot id: A0LLH0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

335543:SFUM RS01875
gene id: 335543:SFUM_RS01875
uniprot id: A0LF66
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

335543:SFUM RS09135
gene id: 335543:SFUM_RS09135
uniprot id: A0LJ52
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

335543:SFUM RS01305
gene id: 335543:SFUM_RS01305
uniprot id: A0LEV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

335543:SFUM RS16545
gene id: 335543:SFUM_RS16545
uniprot id: A0LN70
names: Similarity
messages: Belongs to the MlaA family.

335543:SFUM RS11400
gene id: 335543:SFUM_RS11400
uniprot id: A0LKD3
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

335543:SFUM RS10325
gene id: 335543:SFUM_RS10325
uniprot id: A0LJS5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Cell membrane
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Lacks the conserved Asp active site.

335543:SFUM RS05190
gene id: 335543:SFUM_RS05190
uniprot id: A0LGZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
messages: Cytoplasm
messages: Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.

335543:SFUM RS18075
gene id: 335543:SFUM_RS18075
uniprot id: A0LP20
names: Subcellular Location Annotation
messages: Membrane

335543:SFUM RS17400
gene id: 335543:SFUM_RS17400
uniprot id: A0LNN9
names: Subcellular Location Annotation
messages: Membrane

335543:SFUM RS08910
gene id: 335543:SFUM_RS08910
uniprot id: A0LJ09
names: Similarity
messages: Belongs to the glutamate synthase family.

335543:SFUM RS02335
gene id: 335543:SFUM_RS02335
uniprot id: A0LFF4
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

335543:SFUM RS17515
gene id: 335543:SFUM_RS17515
uniprot id: A0LNR3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LamB/PxpA family.
messages: Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
messages: Forms a complex composed of PxpA, PxpB and PxpC.

335543:SFUM RS18270
gene id: 335543:SFUM_RS18270
uniprot id: A0LP57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Membrane

335543:SFUM RS00335
gene id: 335543:SFUM_RS00335
uniprot id: A0LEB4
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

335543:SFUM RS07635
gene id: 335543:SFUM_RS07635
uniprot id: A0LIB0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

335543:SFUM RS17000
gene id: 335543:SFUM_RS17000
uniprot id: A0LNG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

335543:SFUM RS15320
gene id: 335543:SFUM_RS15320
uniprot id: A0LMH6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

335543:SFUM RS03835
gene id: 335543:SFUM_RS03835
uniprot id: A0LG82
names: Similarity
messages: Belongs to the serine/threonine dehydratase family.

335543:SFUM RS11805
gene id: 335543:SFUM_RS11805
uniprot id: A0LKL4
names: Subcellular Location Annotation
messages: Membrane

335543:SFUM RS21000
gene id: 335543:SFUM_RS21000
uniprot id: A0LQN8
names: Cofactor
names: Function
names: Subunit
messages: Binds 2 [4Fe-4S] clusters. In this family the first cluster has a non-standard and varying [4Fe-4S] binding motif CX(2)CX(2)CX(4-5)CP.
messages: Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.
messages: Heterodimer of the IorA and IorB subunits.

335543:SFUM RS22170
gene id: 335543:SFUM_RS22170
uniprot id: A0LPQ9
names: Subcellular Location Annotation
messages: Membrane

335543:SFUM RS18150
gene id: 335543:SFUM_RS18150
uniprot id: A0LP34
names: Similarity
messages: Belongs to the YkuD family.

335543:SFUM RS04715
gene id: 335543:SFUM_RS04715
uniprot id: A0LGQ5
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

335543:SFUM RS07615
gene id: 335543:SFUM_RS07615
uniprot id: A0LIA6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.

335543:SFUM RS10045
gene id: 335543:SFUM_RS10045
uniprot id: A0LJM6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

335543:SFUM RS07445
gene id: 335543:SFUM_RS07445
uniprot id: A0LI73
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

335543:SFUM RS11635
gene id: 335543:SFUM_RS11635
uniprot id: A0LKH7
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

335543:SFUM RS04345
gene id: 335543:SFUM_RS04345
uniprot id: A0LGI1
names: Subcellular Location Annotation
messages: Membrane

335543:SFUM RS20670
gene id: 335543:SFUM_RS20670
uniprot id: A0LQH5
names: Function
names: Similarity
messages: Belongs to the HypA/HybF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.

335543:SFUM RS19360
gene id: 335543:SFUM_RS19360
uniprot id: A0LPR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

335543:SFUM RS07145
gene id: 335543:SFUM_RS07145
uniprot id: A0LI13
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

335543:SFUM RS12235
gene id: 335543:SFUM_RS12235
uniprot id: A0LKU4
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

335543:SFUM RS08815
gene id: 335543:SFUM_RS08815
uniprot id: A0LIZ1
names: Function
names: Similarity
messages: Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).

335543:SFUM RS02925
gene id: 335543:SFUM_RS02925
uniprot id: A0LFR4
names: Subcellular Location Annotation
messages: Cytoplasm

335543:SFUM RS10025
gene id: 335543:SFUM_RS10025
uniprot id: A0LJM3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

335543:SFUM RS11120
gene id: 335543:SFUM_RS11120
uniprot id: A0LK79
names: Similarity
messages: Belongs to the HdrA family.

335543:SFUM RS01825
gene id: 335543:SFUM_RS01825
uniprot id: A0LF56
names: Similarity
messages: Belongs to the N-acylglucosamine 2-epimerase family.

335543:SFUM RS23575
gene id: 335543:SFUM_RS23575
uniprot id: A0LLY4
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

335543:SFUM RS06270
gene id: 335543:SFUM_RS06270
uniprot id: A0LHJ3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell inner membrane
messages: Cytoplasm
messages: May bind 1 zinc ion per subunit.
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

335543:SFUM RS13570
gene id: 335543:SFUM_RS13570
uniprot id: A0LLJ2
names: Subcellular Location Annotation
messages: Membrane

335543:SFUM RS02195
gene id: 335543:SFUM_RS02195
uniprot id: A0LFC7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

335543:SFUM RS18765
gene id: 335543:SFUM_RS18765
uniprot id: A0LPE6
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

335543:SFUM RS10235
gene id: 335543:SFUM_RS10235
uniprot id: A0LJQ8
names: Similarity
messages: Belongs to the HdrA family.

335543:SFUM RS08275
gene id: 335543:SFUM_RS08275
uniprot id: A0LIN6
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PdxA family.
messages: Binds 1 divalent metal cation per subunit. Can use ions such as Zn(2+), Mg(2+) or Co(2+).
messages: Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).
messages: Cytoplasm
messages: Homodimer.
messages: The active site is located at the dimer interface.

335543:SFUM RS09060
gene id: 335543:SFUM_RS09060
uniprot id: A0LJ39
names: Subcellular Location Annotation
messages: Membrane

335543:SFUM RS14005
gene id: 335543:SFUM_RS14005
uniprot id: A0LLS9
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

335543:SFUM RS14480
gene id: 335543:SFUM_RS14480
uniprot id: A0LM17
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

335543:SFUM RS11755
gene id: 335543:SFUM_RS11755
uniprot id: A0LKK4
names: Similarity
messages: Belongs to the UPF0111 family.

335543:SFUM RS08615
gene id: 335543:SFUM_RS08615
uniprot id: A0LIV1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

335543:SFUM RS03765
gene id: 335543:SFUM_RS03765
uniprot id: A0LG71
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell inner membrane

335543:SFUM RS17005
gene id: 335543:SFUM_RS17005
uniprot id: A0LNG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

335543:SFUM RS03635
gene id: 335543:SFUM_RS03635
uniprot id: A0LG45
names: Similarity
names: Subunit
messages: Belongs to the threonine aldolase family.
messages: Homotetramer.

335543:SFUM RS16775
gene id: 335543:SFUM_RS16775
uniprot id: A0LNB5
names: Function
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia.

335543:SFUM RS00190
gene id: 335543:SFUM_RS00190
uniprot id: A0LE85
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.

335543:SFUM RS10880
gene id: 335543:SFUM_RS10880
uniprot id: A0LK34
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

335543:SFUM RS03965
gene id: 335543:SFUM_RS03965
uniprot id: A0LGA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

335543:SFUM RS15680
gene id: 335543:SFUM_RS15680
uniprot id: A0LMK6
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

335543:SFUM RS07370
gene id: 335543:SFUM_RS07370
uniprot id: A0LI59
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

335543:SFUM RS08900
gene id: 335543:SFUM_RS08900
uniprot id: A0LJ07
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Cytoplasm
messages: Homodimer.

335543:SFUM RS19225
gene id: 335543:SFUM_RS19225
uniprot id: A0LPN7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

335543:SFUM RS21895
gene id: 335543:SFUM_RS21895
uniprot id: A0LLS1
names: Subcellular Location Annotation
messages: Membrane

335543:SFUM RS15590
gene id: 335543:SFUM_RS15590
uniprot id: A0LMS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

335543:SFUM RS16415
gene id: 335543:SFUM_RS16415
uniprot id: A0LN46
names: Subcellular Location Annotation
messages: Membrane

335543:SFUM RS02185
gene id: 335543:SFUM_RS02185
uniprot id: A0LFC5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

335543:SFUM RS15775
gene id: 335543:SFUM_RS15775
uniprot id: A0LMM5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

335543:SFUM RS07060
gene id: 335543:SFUM_RS07060
uniprot id: A0LHZ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

335543:SFUM RS20005
gene id: 335543:SFUM_RS20005
uniprot id: A0LQ41
names: Cofactor
names: Subunit
messages: Binds 1 FAD per subunit.
messages: Homodimer.

335543:SFUM RS06030
gene id: 335543:SFUM_RS06030
uniprot id: A0LHF0
names: Subcellular Location Annotation
messages: Membrane

335543:SFUM RS17490
gene id: 335543:SFUM_RS17490
uniprot id: A0LNQ8
names: Cofactor
names: Similarity
messages: Belongs to the WrbA family.
messages: Binds 1 FMN per monomer.

335543:SFUM RS10010
gene id: 335543:SFUM_RS10010
uniprot id: A0LJM0
names: Subcellular Location Annotation
messages: Membrane

335543:SFUM RS15685
gene id: 335543:SFUM_RS15685
uniprot id: A0LMK7
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain.

335543:SFUM RS05375
gene id: 335543:SFUM_RS05375
uniprot id: A0LH26
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

335543:SFUM RS02425
gene id: 335543:SFUM_RS02425
uniprot id: A0LFH1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MlaE permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

335543:SFUM RS15735
gene id: 335543:SFUM_RS15735
uniprot id: A0LML7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-insensitive subfamily.
messages: Cell inner membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force.

335543:SFUM RS07920
gene id: 335543:SFUM_RS07920
uniprot id: A0LIG4
names: Subcellular Location Annotation
messages: Membrane

335543:SFUM RS00295
gene id: 335543:SFUM_RS00295
uniprot id: A0LEA6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

335543:SFUM RS20695
gene id: 335543:SFUM_RS20695
uniprot id: A0LQI0
names: Cofactor
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

335543:SFUM RS14115
gene id: 335543:SFUM_RS14115
uniprot id: A0LLU9
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.
messages: Cytoplasm

335543:SFUM RS12405
gene id: 335543:SFUM_RS12405
uniprot id: A0LKX7
names: Similarity
messages: Belongs to the cytochrome c-552 family.

335543:SFUM RS01495
gene id: 335543:SFUM_RS01495
uniprot id: A0LEZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

335543:SFUM RS13015
gene id: 335543:SFUM_RS13015
uniprot id: A0LL94
names: Subcellular Location Annotation
messages: Membrane

335543:SFUM RS04845
gene id: 335543:SFUM_RS04845
uniprot id: A0LGS7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

335543:SFUM RS22030
gene id: 335543:SFUM_RS22030
uniprot id: A0LNG2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

335543:SFUM RS02965
gene id: 335543:SFUM_RS02965
uniprot id: A0LFS3
names: Similarity
messages: Belongs to the glutamine synthetase family.

335543:SFUM RS19675
gene id: 335543:SFUM_RS19675
uniprot id: A0LPX3
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

335543:SFUM RS01005
gene id: 335543:SFUM_RS01005
uniprot id: A0LEP3
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

335543:SFUM RS16475
gene id: 335543:SFUM_RS16475
uniprot id: A0LN55
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins.

335543:SFUM RS00790
gene id: 335543:SFUM_RS00790
uniprot id: A0LEK2
names: Subcellular Location Annotation
messages: Membrane

335543:SFUM RS08975
gene id: 335543:SFUM_RS08975
uniprot id: A0LJ22
names: Function
messages: Decarboxylates L-threonine-O-3-phosphate to yield (R)-1-amino-2-propanol O-2-phosphate, the precursor for the linkage between the nucleotide loop and the corrin ring in cobalamin.

335543:SFUM RS10670
gene id: 335543:SFUM_RS10670
uniprot id: A0LJZ2
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

335543:SFUM RS09665
gene id: 335543:SFUM_RS09665
uniprot id: A0LJF3
names: Subcellular Location Annotation
messages: Membrane

335543:SFUM RS13065
gene id: 335543:SFUM_RS13065
uniprot id: A0LLA4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

335543:SFUM RS12605
gene id: 335543:SFUM_RS12605
uniprot id: A0LL15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

335543:SFUM RS16065
gene id: 335543:SFUM_RS16065
uniprot id: A0LMX7
names: Similarity
messages: Belongs to the AlaDH/PNT family.

335543:SFUM RS04850
gene id: 335543:SFUM_RS04850
uniprot id: A0LGS8
names: Similarity
messages: Belongs to the LacAB/RpiB family.

335543:SFUM RS00160
gene id: 335543:SFUM_RS00160
uniprot id: A0LE79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

335543:SFUM RS20375
gene id: 335543:SFUM_RS20375
uniprot id: A0LQB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

335543:SFUM RS01370
gene id: 335543:SFUM_RS01370
uniprot id: A0LEW7
names: Cofactor
names: Similarity
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

335543:SFUM RS10785
gene id: 335543:SFUM_RS10785
uniprot id: A0LK14
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.

335543:SFUM RS00055
gene id: 335543:SFUM_RS00055
uniprot id: A0LE61
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

335543:SFUM RS06465
gene id: 335543:SFUM_RS06465
uniprot id: A0LHN0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YajC family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the SecDF-YidC-YajC translocase complex. The SecDF-YidC-YajC translocase forms a supercomplex with SecYEG, called the holo-translocon (HTL).
messages: The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions.

335543:SFUM RS03205
gene id: 335543:SFUM_RS03205
uniprot id: A0LFX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

335543:SFUM RS16540
gene id: 335543:SFUM_RS16540
uniprot id: A0LN68
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

335543:SFUM RS03075
gene id: 335543:SFUM_RS03075
uniprot id: A0LFU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

335543:SFUM RS10985
gene id: 335543:SFUM_RS10985
uniprot id: A0LK54
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

335543:SFUM RS08755
gene id: 335543:SFUM_RS08755
uniprot id: A0LIX9
names: Similarity
messages: Belongs to the GSP E family.

335543:SFUM RS00980
gene id: 335543:SFUM_RS00980
uniprot id: A0LEN8
names: Subcellular Location Annotation
messages: Membrane

335543:SFUM RS16710
gene id: 335543:SFUM_RS16710
uniprot id: A0LNA2
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

335543:SFUM RS04860
gene id: 335543:SFUM_RS04860
uniprot id: A0LGT0
names: Similarity
messages: Belongs to the histone deacetylase family.

335543:SFUM RS15220
gene id: 335543:SFUM_RS15220
uniprot id: A0LMF8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.
messages: Rubredoxin is a small nonheme, iron protein lacking acid-labile sulfide. Its single Fe, chelated to 4 Cys, functions as an electron acceptor and may also stabilize the conformation of the molecule.

335543:SFUM RS14210
gene id: 335543:SFUM_RS14210
uniprot id: A0LLX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

335543:SFUM RS00855
gene id: 335543:SFUM_RS00855
uniprot id: A0LEL4
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

335543:SFUM RS16970
gene id: 335543:SFUM_RS16970
uniprot id: A0LNF4
names: Similarity
messages: Belongs to the UPF0758 family.

335543:SFUM RS13915
gene id: 335543:SFUM_RS13915
uniprot id: A0LLR0
names: Function
names: Similarity
messages: Belongs to the NifU family.
messages: May be involved in the formation or repair of [Fe-S] clusters present in iron-sulfur proteins.

335543:SFUM RS08335
gene id: 335543:SFUM_RS08335
uniprot id: A0LIP7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

335543:SFUM RS14190
gene id: 335543:SFUM_RS14190
uniprot id: A0LLW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

335543:SFUM RS06680
gene id: 335543:SFUM_RS06680
uniprot id: A0LHS2
names: Function
names: Similarity
messages: Belongs to the MinE family.
messages: Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.

335543:SFUM RS02045
gene id: 335543:SFUM_RS02045
uniprot id: A0LFA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MlaE permease family.
messages: Cell inner membrane
messages: Membrane

335543:SFUM RS13395
gene id: 335543:SFUM_RS13395
uniprot id: A0LLF8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

335543:SFUM RS18360
gene id: 335543:SFUM_RS18360
uniprot id: A0LP73
names: Subcellular Location Annotation
messages: Membrane

335543:SFUM RS18225
gene id: 335543:SFUM_RS18225
uniprot id: A0LP48
names: Similarity
messages: Belongs to the peptidase A31 family.

335543:SFUM RS18840
gene id: 335543:SFUM_RS18840
uniprot id: A0LPG1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

335543:SFUM RS17815
gene id: 335543:SFUM_RS17815
uniprot id: A0LNW9
names: Subcellular Location Annotation
messages: Membrane

335543:SFUM RS16250
gene id: 335543:SFUM_RS16250
uniprot id: A0LN13
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

335543:SFUM RS21765
gene id: 335543:SFUM_RS21765
uniprot id: A0LKB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

335543:SFUM RS15125
gene id: 335543:SFUM_RS15125
uniprot id: A0LMD8
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

335543:SFUM RS13975
gene id: 335543:SFUM_RS13975
uniprot id: A0LLS2
names: Subcellular Location Annotation
messages: Membrane

335543:SFUM RS08845
gene id: 335543:SFUM_RS08845
uniprot id: A0LIZ7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

335543:SFUM RS08120
gene id: 335543:SFUM_RS08120
uniprot id: A0LIK4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

335543:SFUM RS09565
gene id: 335543:SFUM_RS09565
uniprot id: A0LJD4
names: Similarity
messages: Belongs to the TPP enzyme family.

335543:SFUM RS01980
gene id: 335543:SFUM_RS01980
uniprot id: A0LF87
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

335543:SFUM RS14435
gene id: 335543:SFUM_RS14435
uniprot id: A0LM10
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

335543:SFUM RS01765
gene id: 335543:SFUM_RS01765
uniprot id: A0LF44
names: Function
names: Similarity
messages: Belongs to the LpxK family.
messages: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

335543:SFUM RS08590
gene id: 335543:SFUM_RS08590
uniprot id: A0LIU6
names: Similarity
messages: Belongs to the peptidase M16 family.

335543:SFUM RS03800
gene id: 335543:SFUM_RS03800
uniprot id: A0LG76
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

335543:SFUM RS21830
gene id: 335543:SFUM_RS21830
uniprot id: A0LL14
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

335543:SFUM RS03325
gene id: 335543:SFUM_RS03325
uniprot id: A0LFZ3
names: Similarity
messages: Belongs to the universal stress protein A family.

335543:SFUM RS07660
gene id: 335543:SFUM_RS07660
uniprot id: A0LIB6
names: Similarity
messages: Belongs to the AOR/FOR family.

335543:SFUM RS11800
gene id: 335543:SFUM_RS11800
uniprot id: A0LKL3
names: Subcellular Location Annotation
messages: Membrane

335543:SFUM RS09610
gene id: 335543:SFUM_RS09610
uniprot id: A0LJE3
names: Subcellular Location Annotation
messages: Membrane

335543:SFUM RS16705
gene id: 335543:SFUM_RS16705
uniprot id: A0LNA1
names: Similarity
messages: Belongs to the UPF0047 family.

335543:SFUM RS15155
gene id: 335543:SFUM_RS15155
uniprot id: A0LME5
names: Subcellular Location Annotation
messages: Membrane

335543:SFUM RS00130
gene id: 335543:SFUM_RS00130
uniprot id: A0LE72
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpB which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpB.

335543:SFUM RS10145
gene id: 335543:SFUM_RS10145
uniprot id: A0LJP4
names: Similarity
messages: Belongs to the radical SAM superfamily. NifB family.

335543:SFUM RS20700
gene id: 335543:SFUM_RS20700
uniprot id: A0LQI1
names: Subcellular Location Annotation
messages: Membrane

335543:SFUM RS08155
gene id: 335543:SFUM_RS08155
uniprot id: A0LIL1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Monomer.

335543:SFUM RS05285
gene id: 335543:SFUM_RS05285
uniprot id: A0LH09
names: Similarity
messages: Belongs to the P(II) protein family.

335543:SFUM RS11720
gene id: 335543:SFUM_RS11720
uniprot id: A0LKJ4
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

335543:SFUM RS01485
gene id: 335543:SFUM_RS01485
uniprot id: A0LEY9
names: Function
names: Similarity
messages: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.

335543:SFUM RS20880
gene id: 335543:SFUM_RS20880
uniprot id: A0LQL7
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

335543:SFUM RS19935
gene id: 335543:SFUM_RS19935
uniprot id: A0LQ26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

335543:SFUM RS09930
gene id: 335543:SFUM_RS09930
uniprot id: A0LJK6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

335543:SFUM RS08085
gene id: 335543:SFUM_RS08085
uniprot id: A0LIJ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

335543:SFUM RS07180
gene id: 335543:SFUM_RS07180
uniprot id: A0LI20
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

335543:SFUM RS12320
gene id: 335543:SFUM_RS12320
uniprot id: A0LKW0
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

335543:SFUM RS06560
gene id: 335543:SFUM_RS06560
uniprot id: A0LHP7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

335543:SFUM RS15290
gene id: 335543:SFUM_RS15290
uniprot id: A0LMH0
names: Similarity
names: Subunit
messages: Belongs to the UPF0210 family.
messages: Homodimer.

335543:SFUM RS20630
gene id: 335543:SFUM_RS20630
uniprot id: A0LQG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

335543:SFUM RS00360
gene id: 335543:SFUM_RS00360
uniprot id: A0LEB9
names: Function
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.

335543:SFUM RS11825
gene id: 335543:SFUM_RS11825
uniprot id: A0LKL8
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

335543:SFUM RS09220
gene id: 335543:SFUM_RS09220
uniprot id: A0LJ69
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).

335543:SFUM RS02330
gene id: 335543:SFUM_RS02330
uniprot id: A0LFF3
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

335543:SFUM RS10705
gene id: 335543:SFUM_RS10705
uniprot id: A0LJZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

335543:SFUM RS14130
gene id: 335543:SFUM_RS14130
uniprot id: A0LLV3
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

335543:SFUM RS12030
gene id: 335543:SFUM_RS12030
uniprot id: A0LKQ5
names: Similarity
messages: Belongs to the AAA ATPase family.

335543:SFUM RS08520
gene id: 335543:SFUM_RS08520
uniprot id: A0LIT0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

335543:SFUM RS03025
gene id: 335543:SFUM_RS03025
uniprot id: A0LFT5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DcuA/DcuB transporter (TC 2.A.13.1) family.
messages: Cell inner membrane
messages: Membrane
messages: Responsible for the transport of C4-dicarboxylates.

335543:SFUM RS00735
gene id: 335543:SFUM_RS00735
uniprot id: A0LEJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

335543:SFUM RS05040
gene id: 335543:SFUM_RS05040
uniprot id: A0LGW4
names: Similarity
messages: Belongs to the FemABX family.

335543:SFUM RS05330
gene id: 335543:SFUM_RS05330
uniprot id: A0LH17
names: Similarity
messages: Belongs to the pyruvoyl-dependent arginine decarboxylase family.

335543:SFUM RS16490
gene id: 335543:SFUM_RS16490
uniprot id: A0LN58
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

335543:SFUM RS07055
gene id: 335543:SFUM_RS07055
uniprot id: A0LHZ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

335543:SFUM RS19185
gene id: 335543:SFUM_RS19185
uniprot id: A0LPM9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

335543:SFUM RS08750
gene id: 335543:SFUM_RS08750
uniprot id: A0LIX8
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

335543:SFUM RS18550
gene id: 335543:SFUM_RS18550
uniprot id: A0LPA9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

335543:SFUM RS19870
gene id: 335543:SFUM_RS19870
uniprot id: A0LQ12
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

335543:SFUM RS07015
gene id: 335543:SFUM_RS07015
uniprot id: A0LHY7
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated Csm2 family.
messages: This subunit may be involved in monitoring complementarity of crRNA and target RNA.

335543:SFUM RS18810
gene id: 335543:SFUM_RS18810
uniprot id: A0LPF5
names: Similarity
messages: Belongs to the YggT family.

335543:SFUM RS17135
gene id: 335543:SFUM_RS17135
uniprot id: A0LNI7
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

335543:SFUM RS08010
gene id: 335543:SFUM_RS08010
uniprot id: A0LII1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

335543:SFUM RS10170
gene id: 335543:SFUM_RS10170
uniprot id: A0LJP8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

335543:SFUM RS14950
gene id: 335543:SFUM_RS14950
uniprot id: A0LMA4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lactate permease family.
messages: Cell inner membrane
messages: Membrane
messages: Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate.

335543:SFUM RS19995
gene id: 335543:SFUM_RS19995
uniprot id: A0LQ39
names: Similarity
messages: Belongs to the RecJ family.

335543:SFUM RS01355
gene id: 335543:SFUM_RS01355
uniprot id: A0LEW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

335543:SFUM RS07550
gene id: 335543:SFUM_RS07550
uniprot id: A0LI94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

335543:SFUM RS17635
gene id: 335543:SFUM_RS17635
uniprot id: A0LNT5
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

335543:SFUM RS09005
gene id: 335543:SFUM_RS09005
uniprot id: A0LJ28
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

335543:SFUM RS05370
gene id: 335543:SFUM_RS05370
uniprot id: A0LH25
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell inner membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

335543:SFUM RS01565
gene id: 335543:SFUM_RS01565
uniprot id: A0LF05
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homotetramer.

335543:SFUM RS13390
gene id: 335543:SFUM_RS13390
uniprot id: A0LLF7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

335543:SFUM RS15760
gene id: 335543:SFUM_RS15760
uniprot id: A0LMM2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

335543:SFUM RS20245
gene id: 335543:SFUM_RS20245
uniprot id: A0LQ91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

335543:SFUM RS13585
gene id: 335543:SFUM_RS13585
uniprot id: A0LLJ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.
messages: Cell inner membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system and for the release of the potassium ions to the cytoplasm.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

335543:SFUM RS11475
gene id: 335543:SFUM_RS11475
uniprot id: A0LKE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

335543:SFUM RS16370
gene id: 335543:SFUM_RS16370
uniprot id: A0LN37
names: Similarity
messages: Belongs to the ABC transporter superfamily.

335543:SFUM RS01935
gene id: 335543:SFUM_RS01935
uniprot id: A0LF78
names: Subcellular Location Annotation
messages: Membrane

335543:SFUM RS05185
gene id: 335543:SFUM_RS05185
uniprot id: A0LGY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

335543:SFUM RS08225
gene id: 335543:SFUM_RS08225
uniprot id: A0LIM5
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

335543:SFUM RS09620
gene id: 335543:SFUM_RS09620
uniprot id: A0LJE5
names: Subcellular Location Annotation
messages: Membrane

335543:SFUM RS01750
gene id: 335543:SFUM_RS01750
uniprot id: A0LF41
names: Similarity
messages: Belongs to the heat shock protein 70 family.

335543:SFUM RS07395
gene id: 335543:SFUM_RS07395
uniprot id: A0LI64
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

335543:SFUM RS15710
gene id: 335543:SFUM_RS15710
uniprot id: A0LML2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

335543:SFUM RS16920
gene id: 335543:SFUM_RS16920
uniprot id: A0LNE4
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).

335543:SFUM RS01050
gene id: 335543:SFUM_RS01050
uniprot id: A0LEQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

335543:SFUM RS04390
gene id: 335543:SFUM_RS04390
uniprot id: A0LGJ0
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

335543:SFUM RS02220
gene id: 335543:SFUM_RS02220
uniprot id: A0LFD2
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

335543:SFUM RS14990
gene id: 335543:SFUM_RS14990
uniprot id: A0LMB2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

335543:SFUM RS07675
gene id: 335543:SFUM_RS07675
uniprot id: A0LIB9
names: Subcellular Location Annotation
messages: Membrane

335543:SFUM RS08030
gene id: 335543:SFUM_RS08030
uniprot id: A0LII5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

335543:SFUM RS07405
gene id: 335543:SFUM_RS07405
uniprot id: A0LI66
names: Similarity
messages: Belongs to the acylphosphatase family.

335543:SFUM RS08530
gene id: 335543:SFUM_RS08530
uniprot id: A0LIT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

335543:SFUM RS13000
gene id: 335543:SFUM_RS13000
uniprot id: A0LL91
names: Similarity
messages: Belongs to the BMP lipoprotein family.

335543:SFUM RS16625
gene id: 335543:SFUM_RS16625
uniprot id: A0LN86
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

335543:SFUM RS02380
gene id: 335543:SFUM_RS02380
uniprot id: A0LFG2
names: Similarity
messages: Belongs to the band 7/mec-2 family.

335543:SFUM RS13910
gene id: 335543:SFUM_RS13910
uniprot id: A0LLQ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
messages: Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Seems to participate in the biosynthesis of the nitrogenase metalloclusters by providing the inorganic sulfur required for the Fe-S core formation.
messages: Homodimer.

335543:SFUM RS08970
gene id: 335543:SFUM_RS08970
uniprot id: A0LJ21
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

335543:SFUM RS03940
gene id: 335543:SFUM_RS03940
uniprot id: A0LGA2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Pal lipoprotein family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

335543:SFUM RS09190
gene id: 335543:SFUM_RS09190
uniprot id: A0LJ63
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

335543:SFUM RS00125
gene id: 335543:SFUM_RS00125
uniprot id: A0LE71
names: Similarity
messages: Belongs to the peptidase S16 family.

335543:SFUM RS11690
gene id: 335543:SFUM_RS11690
uniprot id: A0LKI8
names: Similarity
messages: Belongs to the AAA ATPase family.

335543:SFUM RS06625
gene id: 335543:SFUM_RS06625
uniprot id: A0LHQ9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane

335543:SFUM RS08930
gene id: 335543:SFUM_RS08930
uniprot id: A0LJ13
names: Function
names: Similarity
messages: Belongs to the OMP decarboxylase family.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).

335543:SFUM RS12490
gene id: 335543:SFUM_RS12490
uniprot id: A0LKZ3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MlaE permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

335543:SFUM RS05050
gene id: 335543:SFUM_RS05050
uniprot id: A0LGW6
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

335543:SFUM RS00025
gene id: 335543:SFUM_RS00025
uniprot id: A0LE55
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

335543:SFUM RS14795
gene id: 335543:SFUM_RS14795
uniprot id: A0LM78
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

335543:SFUM RS16695
gene id: 335543:SFUM_RS16695
uniprot id: A0LN99
names: Similarity
messages: Belongs to the peptidase M16 family.

335543:SFUM RS06325
gene id: 335543:SFUM_RS06325
uniprot id: A0LHK3
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

335543:SFUM RS12435
gene id: 335543:SFUM_RS12435
uniprot id: A0LKY3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

335543:SFUM RS08165
gene id: 335543:SFUM_RS08165
uniprot id: A0LIL3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

335543:SFUM RS09040
gene id: 335543:SFUM_RS09040
uniprot id: A0LJ35
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Part of an ABC transporter complex. Responsible for energy coupling to the transport system.

335543:SFUM RS22235
gene id: 335543:SFUM_RS22235
uniprot id: A0LQM5
names: Similarity
messages: Belongs to the peptidase S11 family.

335543:SFUM RS13025
gene id: 335543:SFUM_RS13025
uniprot id: A0LL96
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

335543:SFUM RS18085
gene id: 335543:SFUM_RS18085
uniprot id: A0LP22
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

335543:SFUM RS17320
gene id: 335543:SFUM_RS17320
uniprot id: A0LNM5
names: Similarity
messages: Belongs to the ABC transporter superfamily.

335543:SFUM RS18120
gene id: 335543:SFUM_RS18120
uniprot id: A0LP28
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
messages: In the C-terminal section; belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

335543:SFUM RS19385
gene id: 335543:SFUM_RS19385
uniprot id: A0LPR6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

335543:SFUM RS14240
gene id: 335543:SFUM_RS14240
uniprot id: A0LLX4
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily.
messages: Binds 1 NADP(+) per subunit.
messages: Catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose.
messages: Contains a large N-terminal NADP-binding domain, and a smaller C-terminal substrate-binding domain.
messages: Homopentamer.

335543:SFUM RS02360
gene id: 335543:SFUM_RS02360
uniprot id: A0LFF8
names: Activity Regulation
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LDH/MDH superfamily. MDH type 2 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate. Catalyzes the reduction of oxaloacetate more efficiently than the oxidation of malate.
messages: Homodimer.
messages: Substrate inhibition is observed at high concentrations of oxaloacetate.

335543:SFUM RS13445
gene id: 335543:SFUM_RS13445
uniprot id: A0LLG8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

335543:SFUM RS15540
gene id: 335543:SFUM_RS15540
uniprot id: A0LMM0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpB which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpB.

335543:SFUM RS19390
gene id: 335543:SFUM_RS19390
uniprot id: A0LPR7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
messages: Cytoplasm
messages: Homotrimer.
messages: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

335543:SFUM RS07330
gene id: 335543:SFUM_RS07330
uniprot id: A0LI51
names: Similarity
messages: Belongs to the Nudix hydrolase family.

335543:SFUM RS06630
gene id: 335543:SFUM_RS06630
uniprot id: A0LHR1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

335543:SFUM RS01235
gene id: 335543:SFUM_RS01235
uniprot id: A0LEU0
names: Subcellular Location Annotation
messages: Membrane

335543:SFUM RS15755
gene id: 335543:SFUM_RS15755
uniprot id: A0LMM1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

335543:SFUM RS13060
gene id: 335543:SFUM_RS13060
uniprot id: A0LLA3
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

335543:SFUM RS04340
gene id: 335543:SFUM_RS04340
uniprot id: A0LGI0
names: Subcellular Location Annotation
messages: Membrane

335543:SFUM RS16555
gene id: 335543:SFUM_RS16555
uniprot id: A0LN72
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

335543:SFUM RS05900
gene id: 335543:SFUM_RS05900
uniprot id: A0LHC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Membrane

335543:SFUM RS08095
gene id: 335543:SFUM_RS08095
uniprot id: A0LIJ8
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

335543:SFUM RS13460
gene id: 335543:SFUM_RS13460
uniprot id: A0LLH1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

335543:SFUM RS02810
gene id: 335543:SFUM_RS02810
uniprot id: A0LFP2
names: Function
names: Similarity
messages: Belongs to the QueH family.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).

335543:SFUM RS05260
gene id: 335543:SFUM_RS05260
uniprot id: A0LH04
names: Similarity
messages: Belongs to the NifD/NifK/NifE/NifN family.

335543:SFUM RS12875
gene id: 335543:SFUM_RS12875
uniprot id: A0LL69
names: Similarity
messages: Belongs to the FeoA family.

335543:SFUM RS22105
gene id: 335543:SFUM_RS22105
uniprot id: A0LP84
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

335543:SFUM RS02950
gene id: 335543:SFUM_RS02950
uniprot id: A0LFR9
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

335543:SFUM RS10155
gene id: 335543:SFUM_RS10155
uniprot id: A0LJP6
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

335543:SFUM RS07350
gene id: 335543:SFUM_RS07350
uniprot id: A0LI55
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

335543:SFUM RS20130
gene id: 335543:SFUM_RS20130
uniprot id: A0LQ67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

335543:SFUM RS16465
gene id: 335543:SFUM_RS16465
uniprot id: A0LN53
names: Function
names: Similarity
messages: Belongs to the ribF family.
messages: Catalyzes the phosphorylation of riboflavin to FMN followed by the adenylation of FMN to FAD.

335543:SFUM RS23475
gene id: 335543:SFUM_RS23475
uniprot id: A0LHG9
names: Similarity
messages: Belongs to the HdrA family.

335543:SFUM RS17565
gene id: 335543:SFUM_RS17565
uniprot id: A0LNS3
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

335543:SFUM RS17670
gene id: 335543:SFUM_RS17670
uniprot id: A0LNU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

335543:SFUM RS14475
gene id: 335543:SFUM_RS14475
uniprot id: A0LM16
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

335543:SFUM RS08625
gene id: 335543:SFUM_RS08625
uniprot id: A0LIV3
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

335543:SFUM RS10265
gene id: 335543:SFUM_RS10265
uniprot id: A0LJR4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm

335543:SFUM RS16220
gene id: 335543:SFUM_RS16220
uniprot id: A0LN07
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

335543:SFUM RS04245
gene id: 335543:SFUM_RS04245
uniprot id: A0LGG3
names: Similarity
messages: Belongs to the universal stress protein A family.

335543:SFUM RS16360
gene id: 335543:SFUM_RS16360
uniprot id: A0LN35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

335543:SFUM RS14070
gene id: 335543:SFUM_RS14070
uniprot id: A0LLU1
names: Subcellular Location Annotation
messages: Periplasm

335543:SFUM RS01590
gene id: 335543:SFUM_RS01590
uniprot id: A0LF11
names: Subcellular Location Annotation
messages: Membrane

335543:SFUM RS17410
gene id: 335543:SFUM_RS17410
uniprot id: A0LNP1
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

335543:SFUM RS15330
gene id: 335543:SFUM_RS15330
uniprot id: A0LMH8
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

335543:SFUM RS16265
gene id: 335543:SFUM_RS16265
uniprot id: A0LN16
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

335543:SFUM RS11760
gene id: 335543:SFUM_RS11760
uniprot id: A0LKK5
names: Subcellular Location Annotation
messages: Membrane

335543:SFUM RS06605
gene id: 335543:SFUM_RS06605
uniprot id: A0LHQ5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

335543:SFUM RS13825
gene id: 335543:SFUM_RS13825
uniprot id: A0LLP2
names: Function
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

335543:SFUM RS05175
gene id: 335543:SFUM_RS05175
uniprot id: A0LGY7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

335543:SFUM RS15145
gene id: 335543:SFUM_RS15145
uniprot id: A0LME3
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

335543:SFUM RS00570
gene id: 335543:SFUM_RS00570
uniprot id: A0LEF7
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

335543:SFUM RS06255
gene id: 335543:SFUM_RS06255
uniprot id: A0LHJ0
names: Subcellular Location Annotation
messages: Membrane

335543:SFUM RS15565
gene id: 335543:SFUM_RS15565
uniprot id: A0LMM5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

335543:SFUM RS00235
gene id: 335543:SFUM_RS00235
uniprot id: A0LE94
names: Similarity
messages: Belongs to the ClpA/ClpB family.

335543:SFUM RS15575
gene id: 335543:SFUM_RS15575
uniprot id: A0LMM7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

335543:SFUM RS00045
gene id: 335543:SFUM_RS00045
uniprot id: A0LE59
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

335543:SFUM RS15035
gene id: 335543:SFUM_RS15035
uniprot id: A0LMC1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAD-like hydrolase superfamily. PhnX family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Involved in phosphonate degradation.

335543:SFUM RS05995
gene id: 335543:SFUM_RS05995
uniprot id: A0LHE3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: In the N-terminal section; belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.

335543:SFUM RS08860
gene id: 335543:SFUM_RS08860
uniprot id: A0LJ00
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm

335543:SFUM RS07000
gene id: 335543:SFUM_RS07000
uniprot id: A0LHY4
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated Csm5 family.
messages: This subunit might be involved in maturation of a crRNA intermediate to its mature form.

335543:SFUM RS15090
gene id: 335543:SFUM_RS15090
uniprot id: A0LMD2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

335543:SFUM RS14470
gene id: 335543:SFUM_RS14470
uniprot id: A0LM15
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

335543:SFUM RS08125
gene id: 335543:SFUM_RS08125
uniprot id: A0LIK5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

335543:SFUM RS19355
gene id: 335543:SFUM_RS19355
uniprot id: A0LPR0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

335543:SFUM RS16495
gene id: 335543:SFUM_RS16495
uniprot id: A0LN59
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

335543:SFUM RS15075
gene id: 335543:SFUM_RS15075
uniprot id: A0LMB4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

335543:SFUM RS18830
gene id: 335543:SFUM_RS18830
uniprot id: A0LPF9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

335543:SFUM RS18700
gene id: 335543:SFUM_RS18700
uniprot id: A0LPD8
names: Subcellular Location Annotation
messages: Membrane

335543:SFUM RS11155
gene id: 335543:SFUM_RS11155
uniprot id: A0LK86
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

335543:SFUM RS06300
gene id: 335543:SFUM_RS06300
uniprot id: A0LHJ9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

335543:SFUM RS19190
gene id: 335543:SFUM_RS19190
uniprot id: A0LPN0
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

335543:SFUM RS17810
gene id: 335543:SFUM_RS17810
uniprot id: A0LNW8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Cu-Zn superoxide dismutase family.
messages: Binds 1 copper ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

335543:SFUM RS20550
gene id: 335543:SFUM_RS20550
uniprot id: A0LQF6
names: Subcellular Location Annotation
messages: Membrane

335543:SFUM RS00940
gene id: 335543:SFUM_RS00940
uniprot id: A0LEN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

335543:SFUM RS07210
gene id: 335543:SFUM_RS07210
uniprot id: A0LI27
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

335543:SFUM RS01930
gene id: 335543:SFUM_RS01930
uniprot id: A0LF77
names: Function
names: Similarity
messages: Belongs to the phenylacetyl-CoA ligase family.
messages: Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).

335543:SFUM RS12160
gene id: 335543:SFUM_RS12160
uniprot id: A0LKS9
names: Similarity
messages: Belongs to the glycosyl hydrolase 57 family.

335543:SFUM RS11085
gene id: 335543:SFUM_RS11085
uniprot id: A0LK72
names: Subcellular Location Annotation
messages: Membrane

335543:SFUM RS08295
gene id: 335543:SFUM_RS08295
uniprot id: A0LIP0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase A chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.

335543:SFUM RS17295
gene id: 335543:SFUM_RS17295
uniprot id: A0LNM0
names: Similarity
messages: Belongs to the FemABX family.

335543:SFUM RS05985
gene id: 335543:SFUM_RS05985
uniprot id: A0LHE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

335543:SFUM RS05450
gene id: 335543:SFUM_RS05450
uniprot id: A0LH38
names: Similarity
messages: Belongs to the sulfate adenylyltransferase family.

335543:SFUM RS07765
gene id: 335543:SFUM_RS07765
uniprot id: A0LID7
names: Subcellular Location Annotation
messages: Membrane

335543:SFUM RS06455
gene id: 335543:SFUM_RS06455
uniprot id: A0LHM8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

335543:SFUM RS04330
gene id: 335543:SFUM_RS04330
uniprot id: A0LGH8
names: Function
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.
messages: In the C-terminal section; belongs to the aldehyde dehydrogenase family.
messages: In the N-terminal section; belongs to the proline dehydrogenase family.
messages: Oxidizes proline to glutamate for use as a carbon and nitrogen source.

335543:SFUM RS11405
gene id: 335543:SFUM_RS11405
uniprot id: A0LKD4
names: Subcellular Location Annotation
messages: Membrane

335543:SFUM RS05590
gene id: 335543:SFUM_RS05590
uniprot id: A0LH67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

335543:SFUM RS12085
gene id: 335543:SFUM_RS12085
uniprot id: A0LKR5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I fumarase family.
messages: Catalyzes the reversible hydration of fumarate to (S)-malate.
messages: Homodimer.

335543:SFUM RS16355
gene id: 335543:SFUM_RS16355
uniprot id: A0LN34
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

335543:SFUM RS10345
gene id: 335543:SFUM_RS10345
uniprot id: A0LJS9
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

335543:SFUM RS08100
gene id: 335543:SFUM_RS08100
uniprot id: A0LIJ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

335543:SFUM RS17550
gene id: 335543:SFUM_RS17550
uniprot id: A0LNS0
names: Subcellular Location Annotation
messages: Membrane

335543:SFUM RS05895
gene id: 335543:SFUM_RS05895
uniprot id: A0LHC1
names: Subcellular Location Annotation
messages: Periplasm

335543:SFUM RS18380
gene id: 335543:SFUM_RS18380
uniprot id: A0LP77
names: Subcellular Location Annotation
messages: Membrane

335543:SFUM RS12350
gene id: 335543:SFUM_RS12350
uniprot id: A0LKW6
names: Subcellular Location Annotation
messages: Membrane

335543:SFUM RS07245
gene id: 335543:SFUM_RS07245
uniprot id: A0LI34
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

335543:SFUM RS06935
gene id: 335543:SFUM_RS06935
uniprot id: A0LHX1
names: Similarity
messages: Belongs to the spermidine/spermine synthase family.

335543:SFUM RS16025
gene id: 335543:SFUM_RS16025
uniprot id: A0LMW9
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

335543:SFUM RS00550
gene id: 335543:SFUM_RS00550
uniprot id: A0LEF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP G family.
messages: Cell inner membrane
messages: Membrane

335543:SFUM RS21605
gene id: 335543:SFUM_RS21605
uniprot id: A0LIE5
names: Subcellular Location Annotation
messages: Membrane

335543:SFUM RS06915
gene id: 335543:SFUM_RS06915
uniprot id: A0LHW7
names: Subunit
messages: Heterodimer of a large and a small subunit.

335543:SFUM RS02910
gene id: 335543:SFUM_RS02910
uniprot id: A0LFR1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

335543:SFUM RS13020
gene id: 335543:SFUM_RS13020
uniprot id: A0LL95
names: Subunit
messages: Heterodimer of a large and a small subunit.

335543:SFUM RS08175
gene id: 335543:SFUM_RS08175
uniprot id: A0LIL5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

335543:SFUM RS08205
gene id: 335543:SFUM_RS08205
uniprot id: A0LIM0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
messages: Cytoplasm

335543:SFUM RS12140
gene id: 335543:SFUM_RS12140
uniprot id: A0LKS5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

335543:SFUM RS02765
gene id: 335543:SFUM_RS02765
uniprot id: A0LFN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

335543:SFUM RS15785
gene id: 335543:SFUM_RS15785
uniprot id: A0LMM7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

335543:SFUM RS07020
gene id: 335543:SFUM_RS07020
uniprot id: A0LHY8
names: Similarity
messages: Belongs to the CRISPR-associated Cas10/Csm1 family.

335543:SFUM RS01600
gene id: 335543:SFUM_RS01600
uniprot id: A0LF13
names: Similarity
messages: Belongs to the leucine-binding protein family.

335543:SFUM RS03500
gene id: 335543:SFUM_RS03500
uniprot id: A0LG27
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

335543:SFUM RS18325
gene id: 335543:SFUM_RS18325
uniprot id: A0LP66
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

335543:SFUM RS06460
gene id: 335543:SFUM_RS06460
uniprot id: A0LHM9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

335543:SFUM RS05215
gene id: 335543:SFUM_RS05215
uniprot id: A0LGZ5
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

335543:SFUM RS08310
gene id: 335543:SFUM_RS08310
uniprot id: A0LIP3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

335543:SFUM RS08020
gene id: 335543:SFUM_RS08020
uniprot id: A0LII3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

335543:SFUM RS13945
gene id: 335543:SFUM_RS13945
uniprot id: A0LLR6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

335543:SFUM RS12650
gene id: 335543:SFUM_RS12650
uniprot id: A0LL24
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

335543:SFUM RS10120
gene id: 335543:SFUM_RS10120
uniprot id: A0LJN9
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

335543:SFUM RS15660
gene id: 335543:SFUM_RS15660
uniprot id: A0LMK2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

335543:SFUM RS16945
gene id: 335543:SFUM_RS16945
uniprot id: A0LNE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

335543:SFUM RS10350
gene id: 335543:SFUM_RS10350
uniprot id: A0LJT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Cell inner membrane
messages: Membrane

335543:SFUM RS05170
gene id: 335543:SFUM_RS05170
uniprot id: A0LGY6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

335543:SFUM RS10100
gene id: 335543:SFUM_RS10100
uniprot id: A0LJN5
names: Similarity
messages: Belongs to the GPI family.

335543:SFUM RS02580
gene id: 335543:SFUM_RS02580
uniprot id: A0LFK0
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

335543:SFUM RS05730
gene id: 335543:SFUM_RS05730
uniprot id: A0LH93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CbiQ family.
messages: Membrane

335543:SFUM RS14790
gene id: 335543:SFUM_RS14790
uniprot id: A0LM77
names: Cofactor
names: Similarity
messages: Belongs to the PyrK family.
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.

335543:SFUM RS20045
gene id: 335543:SFUM_RS20045
uniprot id: A0LQ51
names: Similarity
messages: Belongs to the MT-A70-like family.

335543:SFUM RS20905
gene id: 335543:SFUM_RS20905
uniprot id: A0LQM2
names: Similarity
messages: Belongs to the histone deacetylase family.

335543:SFUM RS08255
gene id: 335543:SFUM_RS08255
uniprot id: A0LIN2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

335543:SFUM RS09035
gene id: 335543:SFUM_RS09035
uniprot id: A0LJ34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

335543:SFUM RS12760
gene id: 335543:SFUM_RS12760
uniprot id: A0LL48
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

335543:SFUM RS00475
gene id: 335543:SFUM_RS00475
uniprot id: A0LEE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HupC/HyaC/HydC family.
messages: Membrane

335543:SFUM RS09075
gene id: 335543:SFUM_RS09075
uniprot id: A0LJ41
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

335543:SFUM RS04670
gene id: 335543:SFUM_RS04670
uniprot id: A0LGP5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.
messages: Cytoplasm
messages: Monomer.

335543:SFUM RS16840
gene id: 335543:SFUM_RS16840
uniprot id: A0LNC7
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

335543:SFUM RS21315
gene id: 335543:SFUM_RS21315
uniprot id: A0LFW9
names: Subcellular Location Annotation
messages: Membrane

335543:SFUM RS00395
gene id: 335543:SFUM_RS00395
uniprot id: A0LEC6
names: Similarity
messages: Belongs to the MEMO1 family.

335543:SFUM RS02180
gene id: 335543:SFUM_RS02180
uniprot id: A0LFC4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

335543:SFUM RS04315
gene id: 335543:SFUM_RS04315
uniprot id: A0LGH5
names: Subcellular Location Annotation
messages: Membrane

335543:SFUM RS10810
gene id: 335543:SFUM_RS10810
uniprot id: A0LK20
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

335543:SFUM RS13990
gene id: 335543:SFUM_RS13990
uniprot id: A0LLS5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

335543:SFUM RS12240
gene id: 335543:SFUM_RS12240
uniprot id: A0LKU5
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

335543:SFUM RS13835
gene id: 335543:SFUM_RS13835
uniprot id: A0LLP5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Cob(I)alamin adenosyltransferase family.
messages: Cytoplasm
messages: Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids.

335543:SFUM RS18155
gene id: 335543:SFUM_RS18155
uniprot id: A0LP35
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

335543:SFUM RS00255
gene id: 335543:SFUM_RS00255
uniprot id: A0LE98
names: Similarity
messages: Belongs to the carbamate kinase family.

335543:SFUM RS00320
gene id: 335543:SFUM_RS00320
uniprot id: A0LEB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

335543:SFUM RS03160
gene id: 335543:SFUM_RS03160
uniprot id: A0LFW2
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

335543:SFUM RS14100
gene id: 335543:SFUM_RS14100
uniprot id: A0LLU6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Monomer.

335543:SFUM RS14265
gene id: 335543:SFUM_RS14265
uniprot id: A0LLX9
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

335543:SFUM RS08870
gene id: 335543:SFUM_RS08870
uniprot id: A0LJ02
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

335543:SFUM RS11160
gene id: 335543:SFUM_RS11160
uniprot id: A0LK87
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.

335543:SFUM RS08065
gene id: 335543:SFUM_RS08065
uniprot id: A0LIJ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

335543:SFUM RS04535
gene id: 335543:SFUM_RS04535
uniprot id: A0LGL9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell inner membrane
messages: Cytoplasm
messages: Monomer.

335543:SFUM RS15315
gene id: 335543:SFUM_RS15315
uniprot id: A0LMH5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family.
messages: Heterodimer of a large and a small subunit.
messages: Periplasm

335543:SFUM RS12375
gene id: 335543:SFUM_RS12375
uniprot id: A0LKX2
names: Subcellular Location Annotation
messages: Membrane

335543:SFUM RS01100
gene id: 335543:SFUM_RS01100
uniprot id: A0LER2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

335543:SFUM RS08140
gene id: 335543:SFUM_RS08140
uniprot id: A0LIK8
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

335543:SFUM RS12670
gene id: 335543:SFUM_RS12670
uniprot id: A0LL28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MlaE permease family.
messages: Cell inner membrane
messages: Membrane

335543:SFUM RS21130
gene id: 335543:SFUM_RS21130
uniprot id: A0LQR3
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase IV family.
messages: Converts GTP to 7,8-dihydroneopterin triphosphate.

335543:SFUM RS08810
gene id: 335543:SFUM_RS08810
uniprot id: A0LIZ0
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

335543:SFUM RS03780
gene id: 335543:SFUM_RS03780
uniprot id: A0LG73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

335543:SFUM RS19145
gene id: 335543:SFUM_RS19145
uniprot id: A0LPM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

335543:SFUM RS10820
gene id: 335543:SFUM_RS10820
uniprot id: A0LK22
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

335543:SFUM RS09835
gene id: 335543:SFUM_RS09835
uniprot id: A0LJI8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

335543:SFUM RS07105
gene id: 335543:SFUM_RS07105
uniprot id: A0LI05
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Monomer.

335543:SFUM RS00345
gene id: 335543:SFUM_RS00345
uniprot id: A0LEB6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

335543:SFUM RS00675
gene id: 335543:SFUM_RS00675
uniprot id: A0LEH8
names: Subcellular Location Annotation
messages: Membrane

335543:SFUM RS18845
gene id: 335543:SFUM_RS18845
uniprot id: A0LPG2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

335543:SFUM RS08150
gene id: 335543:SFUM_RS08150
uniprot id: A0LIL0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell inner membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

335543:SFUM RS04395
gene id: 335543:SFUM_RS04395
uniprot id: A0LGJ1
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

335543:SFUM RS18825
gene id: 335543:SFUM_RS18825
uniprot id: A0LPF8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

335543:SFUM RS08090
gene id: 335543:SFUM_RS08090
uniprot id: A0LIJ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

335543:SFUM RS02160
gene id: 335543:SFUM_RS02160
uniprot id: A0LFC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

335543:SFUM RS16820
gene id: 335543:SFUM_RS16820
uniprot id: A0LNC4
names: Similarity
messages: In the N-terminal section; belongs to the zinc metallo-hydrolase group 3 family.

335543:SFUM RS02675
gene id: 335543:SFUM_RS02675
uniprot id: A0LFL7
names: Cofactor
names: Similarity
messages: Belongs to the iron-containing alcohol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.

335543:SFUM RS10245
gene id: 335543:SFUM_RS10245
uniprot id: A0LJR0
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. CpsB/CapC family.

335543:SFUM RS15820
gene id: 335543:SFUM_RS15820
uniprot id: A0LMS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Cell inner membrane
messages: Membrane

335543:SFUM RS13870
gene id: 335543:SFUM_RS13870
uniprot id: A0LLQ2
names: Similarity
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.

335543:SFUM RS13150
gene id: 335543:SFUM_RS13150
uniprot id: A0LLB8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA 3'-terminal cyclase family. Type 1 subfamily.
messages: Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing.
messages: Cytoplasm