326424:FRAAL RS16800
gene id: 326424:FRAAL_RS16800
uniprot id: Q0RJ31
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

326424:FRAAL RS22595
gene id: 326424:FRAAL_RS22595
uniprot id: Q0RFC5
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

326424:FRAAL RS09375
gene id: 326424:FRAAL_RS09375
uniprot id: Q0RNT9
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

326424:FRAAL RS05625
gene id: 326424:FRAAL_RS05625
uniprot id: Q0RR74
names: Subcellular Location Annotation
messages: Cytoplasm

326424:FRAAL RS15345
gene id: 326424:FRAAL_RS15345
uniprot id: Q0RK03
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

326424:FRAAL RS04740
gene id: 326424:FRAAL_RS04740
uniprot id: Q0RRR1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

326424:FRAAL RS27170
gene id: 326424:FRAAL_RS27170
uniprot id: Q0RCH4
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

326424:FRAAL RS09300
gene id: 326424:FRAAL_RS09300
uniprot id: Q0RNV5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Catalyzes the conjugation of the 1'-hydroxyl group of D-myo-inositol-3-phosphate (also named L-myo-inositol-1-phosphate) with a lipid tail of cytidine diphosphate diacylglycerol (CDP-DAG), forming phosphatidylinositol phosphate (PIP) and CMP. PIP is a precursor of phosphatidylinositol (PI) which is an essential lipid required for cell wall formation.
messages: Cell membrane
messages: Contains a di-nuclear catalytic Mg(2+) center.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

326424:FRAAL RS10455
gene id: 326424:FRAAL_RS10455
uniprot id: Q0RN52
names: Similarity
messages: Belongs to the peptidase A31 family.

326424:FRAAL RS04430
gene id: 326424:FRAAL_RS04430
uniprot id: Q0RRX2
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).

326424:FRAAL RS06270
gene id: 326424:FRAAL_RS06270
uniprot id: Q0RQS5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UreD family.
messages: Cytoplasm
messages: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
messages: UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

326424:FRAAL RS10380
gene id: 326424:FRAAL_RS10380
uniprot id: Q0RN73
names: Similarity
messages: Belongs to the glutamate synthase family.

326424:FRAAL RS24830
gene id: 326424:FRAAL_RS24830
uniprot id: Q0RDY1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

326424:FRAAL RS25870
gene id: 326424:FRAAL_RS25870
uniprot id: Q0RDA4
names: Subcellular Location Annotation
messages: Membrane

326424:FRAAL RS12290
gene id: 326424:FRAAL_RS12290
uniprot id: Q0RLY8
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

326424:FRAAL RS04470
gene id: 326424:FRAAL_RS04470
uniprot id: Q0RRW3
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

326424:FRAAL RS24960
gene id: 326424:FRAAL_RS24960
uniprot id: Q0RDV2
names: Similarity
messages: Belongs to the CinA family.

326424:FRAAL RS04710
gene id: 326424:FRAAL_RS04710
uniprot id: Q0RRR7
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

326424:FRAAL RS04245
gene id: 326424:FRAAL_RS04245
uniprot id: Q0RS11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

326424:FRAAL RS15995
gene id: 326424:FRAAL_RS15995
uniprot id: Q0RJK8
names: Similarity
messages: Belongs to the peptidase S33 family.

326424:FRAAL RS07015
gene id: 326424:FRAAL_RS07015
uniprot id: Q0RQ99
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

326424:FRAAL RS05565
gene id: 326424:FRAAL_RS05565
uniprot id: Q0RR88
names: Similarity
messages: Belongs to the UPF0434 family.

326424:FRAAL RS25500
gene id: 326424:FRAAL_RS25500
uniprot id: Q0RDI4
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

326424:FRAAL RS20070
gene id: 326424:FRAAL_RS20070
uniprot id: Q0RH02
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gluconeogenesis factor family.
messages: Cytoplasm
messages: Required for morphogenesis under gluconeogenic growth conditions.

326424:FRAAL RS24945
gene id: 326424:FRAAL_RS24945
uniprot id: Q0RDV6
names: Similarity
messages: Belongs to the PspA/IM30 family.

326424:FRAAL RS12160
gene id: 326424:FRAAL_RS12160
uniprot id: Q0RM16
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

326424:FRAAL RS27415
gene id: 326424:FRAAL_RS27415
uniprot id: Q0RCC1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

326424:FRAAL RS12520
gene id: 326424:FRAAL_RS12520
uniprot id: Q0RLT9
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic ubiquitin-like protein family.
messages: Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation.
messages: Strongly interacts with the proteasome-associated ATPase ARC through a hydrophobic interface; the interacting region of Pup lies in its C-terminal half. There is one Pup binding site per ARC hexamer ring.
messages: The N-terminal unstructured half of Pup provides a signal required to initiate unfolding and degradation by the proteasome but is not needed for pupylation, while the C-terminal helical half of Pup interacts with ARC to target proteins to the proteasome.

326424:FRAAL RS01305
gene id: 326424:FRAAL_RS01305
uniprot id: Q0RTX6
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

326424:FRAAL RS08720
gene id: 326424:FRAAL_RS08720
uniprot id: Q0RP74
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

326424:FRAAL RS09340
gene id: 326424:FRAAL_RS09340
uniprot id: Q0RNU7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

326424:FRAAL RS10040
gene id: 326424:FRAAL_RS10040
uniprot id: Q0RNE2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

326424:FRAAL RS16530
gene id: 326424:FRAAL_RS16530
uniprot id: Q0RJ90
names: Similarity
messages: Belongs to the DNA polymerase type-A family.

326424:FRAAL RS13690
gene id: 326424:FRAAL_RS13690
uniprot id: Q0RL28
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

326424:FRAAL RS10095
gene id: 326424:FRAAL_RS10095
uniprot id: Q0RND1
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

326424:FRAAL RS27515
gene id: 326424:FRAAL_RS27515
uniprot id: Q0RC99
names: Function
messages: TetR is the repressor of the tetracycline resistance element; its N-terminal region forms a helix-turn-helix structure and binds DNA. Binding of tetracycline to TetR reduces the repressor affinity for the tetracycline resistance gene (tetA) promoter operator sites.

326424:FRAAL RS08150
gene id: 326424:FRAAL_RS08150
uniprot id: Q0RPJ5
names: Subcellular Location Annotation
messages: Membrane

326424:FRAAL RS04695
gene id: 326424:FRAAL_RS04695
uniprot id: Q0RRS0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

326424:FRAAL RS02795
gene id: 326424:FRAAL_RS02795
uniprot id: Q0RSZ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CobB/CobQ family. GatD subfamily.
messages: Forms a heterodimer with MurT.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The GatD subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia. The resulting ammonia molecule is channeled to the active site of MurT.

326424:FRAAL RS28030
gene id: 326424:FRAAL_RS28030
uniprot id: Q0RBY4
names: Similarity
messages: Belongs to the IucA/IucC family.

326424:FRAAL RS22785
gene id: 326424:FRAAL_RS22785
uniprot id: Q0RF91
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

326424:FRAAL RS01595
gene id: 326424:FRAAL_RS01595
uniprot id: Q0RTR4
names: Similarity
messages: Belongs to the NtaA/SnaA/DszA monooxygenase family.

326424:FRAAL RS33975
gene id: 326424:FRAAL_RS33975
uniprot id: Q0RLI8
names: Similarity
messages: Belongs to the heat shock protein 70 family.

326424:FRAAL RS22805
gene id: 326424:FRAAL_RS22805
uniprot id: Q0RF87
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

326424:FRAAL RS14620
gene id: 326424:FRAAL_RS14620
uniprot id: Q0RKG3
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

326424:FRAAL RS24910
gene id: 326424:FRAAL_RS24910
uniprot id: Q0RDW5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

326424:FRAAL RS16755
gene id: 326424:FRAAL_RS16755
uniprot id: Q0RJ44
names: Similarity
messages: Belongs to the cytochrome P450 family.

326424:FRAAL RS22680
gene id: 326424:FRAAL_RS22680
uniprot id: Q0RFB2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.

326424:FRAAL RS09620
gene id: 326424:FRAAL_RS09620
uniprot id: Q0RNN6
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

326424:FRAAL RS03855
gene id: 326424:FRAAL_RS03855
uniprot id: Q0RS95
names: Activity Regulation
names: Caution
names: Domain
names: Function
names: Similarity
messages: Belongs to the GlnD family.
messages: Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen fixation and metabolism.
messages: Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity.

326424:FRAAL RS27485
gene id: 326424:FRAAL_RS27485
uniprot id: Q0RCA5
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

326424:FRAAL RS17630
gene id: 326424:FRAAL_RS17630
uniprot id: Q0RIK2
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

326424:FRAAL RS25125
gene id: 326424:FRAAL_RS25125
uniprot id: Q0RDR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

326424:FRAAL RS09085
gene id: 326424:FRAAL_RS09085
uniprot id: Q0RNZ7
names: Subcellular Location Annotation
messages: Membrane

326424:FRAAL RS06205
gene id: 326424:FRAAL_RS06205
uniprot id: Q0RQU1
names: Subcellular Location Annotation
messages: Membrane

326424:FRAAL RS22770
gene id: 326424:FRAAL_RS22770
uniprot id: Q0RF94
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

326424:FRAAL RS25100
gene id: 326424:FRAAL_RS25100
uniprot id: Q0RDS2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

326424:FRAAL RS28655
gene id: 326424:FRAAL_RS28655
uniprot id: Q0RBJ5
names: Similarity
messages: Belongs to the GSP E family.

326424:FRAAL RS18840
gene id: 326424:FRAAL_RS18840
uniprot id: Q0RHR9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane

326424:FRAAL RS21810
gene id: 326424:FRAAL_RS21810
uniprot id: Q0RFU7
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

326424:FRAAL RS21215
gene id: 326424:FRAAL_RS21215
uniprot id: Q0RG85
names: Subcellular Location Annotation
messages: Membrane

326424:FRAAL RS04250
gene id: 326424:FRAAL_RS04250
uniprot id: Q0RS10
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

326424:FRAAL RS04455
gene id: 326424:FRAAL_RS04455
uniprot id: Q0RRW6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 30 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

326424:FRAAL RS22740
gene id: 326424:FRAAL_RS22740
uniprot id: Q0RFA0
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

326424:FRAAL RS03325
gene id: 326424:FRAAL_RS03325
uniprot id: Q0RSL9
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

326424:FRAAL RS25240
gene id: 326424:FRAAL_RS25240
uniprot id: Q0RDP3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

326424:FRAAL RS25515
gene id: 326424:FRAAL_RS25515
uniprot id: Q0RDI1
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

326424:FRAAL RS29915
gene id: 326424:FRAAL_RS29915
uniprot id: Q0RAR7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

326424:FRAAL RS25995
gene id: 326424:FRAAL_RS25995
uniprot id: Q0RD80
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

326424:FRAAL RS11475
gene id: 326424:FRAAL_RS11475
uniprot id: Q0RMH2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

326424:FRAAL RS15640
gene id: 326424:FRAAL_RS15640
uniprot id: Q0RJT8
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

326424:FRAAL RS27920
gene id: 326424:FRAAL_RS27920
uniprot id: Q0RC09
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

326424:FRAAL RS04690
gene id: 326424:FRAAL_RS04690
uniprot id: Q0RRS1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

326424:FRAAL RS20060
gene id: 326424:FRAAL_RS20060
uniprot id: Q0RH05
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

326424:FRAAL RS20525
gene id: 326424:FRAAL_RS20525
uniprot id: Q0RGN6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

326424:FRAAL RS05250
gene id: 326424:FRAAL_RS05250
uniprot id: Q0RRF4
names: Function
names: Similarity
messages: ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
messages: Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.

326424:FRAAL RS24375
gene id: 326424:FRAAL_RS24375
uniprot id: Q0RE79
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

326424:FRAAL RS18375
gene id: 326424:FRAAL_RS18375
uniprot id: Q0RI28
names: Subcellular Location Annotation
messages: Membrane

326424:FRAAL RS24600
gene id: 326424:FRAAL_RS24600
uniprot id: Q0RE29
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

326424:FRAAL RS22790
gene id: 326424:FRAAL_RS22790
uniprot id: Q0RF90
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

326424:FRAAL RS05560
gene id: 326424:FRAAL_RS05560
uniprot id: Q0RR89
names: Similarity
messages: Belongs to the phosphohexose mutase family.

326424:FRAAL RS13150
gene id: 326424:FRAAL_RS13150
uniprot id: Q0RLE9
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

326424:FRAAL RS20875
gene id: 326424:FRAAL_RS20875
uniprot id: Q0RGG1
names: Subcellular Location Annotation
messages: Membrane

326424:FRAAL RS27010
gene id: 326424:FRAAL_RS27010
uniprot id: Q0RCK9
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

326424:FRAAL RS12580
gene id: 326424:FRAAL_RS12580
uniprot id: Q0RLS7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

326424:FRAAL RS22905
gene id: 326424:FRAAL_RS22905
uniprot id: Q0RF67
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase MltG family.
messages: Cell membrane
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

326424:FRAAL RS24030
gene id: 326424:FRAAL_RS24030
uniprot id: Q0REG1
names: Similarity
messages: Belongs to the AAA ATPase family.

326424:FRAAL RS21310
gene id: 326424:FRAAL_RS21310
uniprot id: Q0RG64
names: Similarity
messages: Belongs to the NtaA/SnaA/DszA monooxygenase family.

326424:FRAAL RS04755
gene id: 326424:FRAAL_RS04755
uniprot id: Q0RRQ8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

326424:FRAAL RS21130
gene id: 326424:FRAAL_RS21130
uniprot id: Q0RGA6
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

326424:FRAAL RS27345
gene id: 326424:FRAAL_RS27345
uniprot id: Q0RCD6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

326424:FRAAL RS12500
gene id: 326424:FRAAL_RS12500
uniprot id: Q0RLU3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM61 family.
messages: Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA.
messages: Homotetramer composed of a dimer of dimers.

326424:FRAAL RS05070
gene id: 326424:FRAAL_RS05070
uniprot id: Q0RRJ4
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

326424:FRAAL RS04750
gene id: 326424:FRAAL_RS04750
uniprot id: Q0RRQ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

326424:FRAAL RS14130
gene id: 326424:FRAAL_RS14130
uniprot id: Q0RKT0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane

326424:FRAAL RS18950
gene id: 326424:FRAAL_RS18950
uniprot id: Q70Z03
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterioferritin family.
messages: Homooligomer of 24 subunits, arranged as 12 dimers, that are packed together to form an approximately spherical molecule with a central cavity, in which large amounts of iron can be deposited.
messages: Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.

326424:FRAAL RS09365
gene id: 326424:FRAAL_RS09365
uniprot id: Q0RNU1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

326424:FRAAL RS09495
gene id: 326424:FRAAL_RS09495
uniprot id: Q0RNR3
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

326424:FRAAL RS06145
gene id: 326424:FRAAL_RS06145
uniprot id: Q0RQV3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the aldolase class II family. MtnB subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P).

326424:FRAAL RS28345
gene id: 326424:FRAAL_RS28345
uniprot id: Q0RBR1
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

326424:FRAAL RS13920
gene id: 326424:FRAAL_RS13920
uniprot id: Q0RKX4
names: Similarity
messages: Belongs to the fatty acid desaturase type 2 family.

326424:FRAAL RS25095
gene id: 326424:FRAAL_RS25095
uniprot id: Q0RDS4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

326424:FRAAL RS29045
gene id: 326424:FRAAL_RS29045
uniprot id: Q0RBA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

326424:FRAAL RS27915
gene id: 326424:FRAAL_RS27915
uniprot id: Q0RC10
names: Similarity
messages: Belongs to the UDPGP type 2 family.

326424:FRAAL RS08205
gene id: 326424:FRAAL_RS08205
uniprot id: Q0RPI3
names: Subcellular Location Annotation
messages: Membrane

326424:FRAAL RS02645
gene id: 326424:FRAAL_RS02645
uniprot id: Q0RT18
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

326424:FRAAL RS19680
gene id: 326424:FRAAL_RS19680
uniprot id: Q0RH88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the encapsulin family. Family 1 subfamily.
messages: Encapsulin nanocompartment

326424:FRAAL RS17580
gene id: 326424:FRAAL_RS17580
uniprot id: Q0RIL4
names: Similarity
messages: Belongs to the cytochrome P450 family.

326424:FRAAL RS19290
gene id: 326424:FRAAL_RS19290
uniprot id: Q0RHH4
names: Similarity
messages: Belongs to the ACC deaminase/D-cysteine desulfhydrase family.

326424:FRAAL RS25485
gene id: 326424:FRAAL_RS25485
uniprot id: Q0RDI7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

326424:FRAAL RS06135
gene id: 326424:FRAAL_RS06135
uniprot id: Q0RQV5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acireductone dioxygenase (ARD) family.
messages: Binds 1 Fe(2+) cation per monomer.
messages: Binds 1 nickel ion per monomer.
messages: Catalyzes 2 different reactions between oxygen and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
messages: Monomer.

326424:FRAAL RS25805
gene id: 326424:FRAAL_RS25805
uniprot id: Q0RDB8
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

326424:FRAAL RS04550
gene id: 326424:FRAAL_RS04550
uniprot id: Q0RRU6
names: Similarity
messages: Belongs to the UPF0234 family.

326424:FRAAL RS22460
gene id: 326424:FRAAL_RS22460
uniprot id: Q0RFF4
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

326424:FRAAL RS25055
gene id: 326424:FRAAL_RS25055
uniprot id: Q0RDT2
names: Similarity
messages: Belongs to the peptidase M16 family.

326424:FRAAL RS25895
gene id: 326424:FRAAL_RS25895
uniprot id: Q0RD99
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

326424:FRAAL RS25020
gene id: 326424:FRAAL_RS25020
uniprot id: Q0RDT9
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

326424:FRAAL RS28755
gene id: 326424:FRAAL_RS28755
uniprot id: Q0RBH5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

326424:FRAAL RS22620
gene id: 326424:FRAAL_RS22620
uniprot id: Q0RFC0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An FAD-requiring monooxygenase active on some tetracycline antibiotic derivatives, which leads to their inactivation. Hydroxylates carbon 11a of tetracycline and some analogs.
messages: Belongs to the aromatic-ring hydroxylase family. TetX subfamily.
messages: Consists of an N-terminal FAD-binding domain with a Rossman fold and a C-terminal substrate-binding domain.
messages: Cytoplasm
messages: Monomer.

326424:FRAAL RS29750
gene id: 326424:FRAAL_RS29750
uniprot id: Q0RAV5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NifD/NifK/NifE/NifN family.
messages: Tetramer of two alpha and two beta chains. Forms complex with the iron protein (nitrogenase component 2).
messages: This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation.

326424:FRAAL RS23190
gene id: 326424:FRAAL_RS23190
uniprot id: Q0RF00
names: Subcellular Location Annotation
messages: Membrane

326424:FRAAL RS27445
gene id: 326424:FRAAL_RS27445
uniprot id: Q0RCB5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Belongs to the precorrin methyltransferase family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

326424:FRAAL RS00080
gene id: 326424:FRAAL_RS00080
uniprot id: Q0RUP1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

326424:FRAAL RS17275
gene id: 326424:FRAAL_RS17275
uniprot id: Q0RIT0
names: Subcellular Location Annotation
messages: Membrane

326424:FRAAL RS04945
gene id: 326424:FRAAL_RS04945
uniprot id: Q0RRL9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

326424:FRAAL RS14070
gene id: 326424:FRAAL_RS14070
uniprot id: Q0RKU3
names: Similarity
messages: Belongs to the bacterial phospholipase C family.

326424:FRAAL RS15065
gene id: 326424:FRAAL_RS15065
uniprot id: Q0RK63
names: Similarity
messages: Belongs to the cytochrome P450 family.

326424:FRAAL RS15695
gene id: 326424:FRAAL_RS15695
uniprot id: Q0RJS6
names: Subcellular Location Annotation
messages: Membrane

326424:FRAAL RS02255
gene id: 326424:FRAAL_RS02255
uniprot id: Q0RTA5
names: Similarity
messages: Belongs to the band 7/mec-2 family. Flotillin subfamily.

326424:FRAAL RS05210
gene id: 326424:FRAAL_RS05210
uniprot id: Q0RRG2
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

326424:FRAAL RS03060
gene id: 326424:FRAAL_RS03060
uniprot id: Q0RSS7
names: Subcellular Location Annotation
messages: Membrane

326424:FRAAL RS25610
gene id: 326424:FRAAL_RS25610
uniprot id: Q0RDG2
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

326424:FRAAL RS04505
gene id: 326424:FRAAL_RS04505
uniprot id: Q0RRV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

326424:FRAAL RS04795
gene id: 326424:FRAAL_RS04795
uniprot id: Q0RRQ0
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

326424:FRAAL RS25480
gene id: 326424:FRAAL_RS25480
uniprot id: Q0RDI8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.

326424:FRAAL RS25925
gene id: 326424:FRAAL_RS25925
uniprot id: Q0RD93
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

326424:FRAAL RS13770
gene id: 326424:FRAAL_RS13770
uniprot id: Q0RL10
names: Similarity
messages: Belongs to the HIBADH-related family.

326424:FRAAL RS08405
gene id: 326424:FRAAL_RS08405
uniprot id: Q0RPE6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein L14 (rplN).

326424:FRAAL RS20435
gene id: 326424:FRAAL_RS20435
uniprot id: Q0RGR0
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

326424:FRAAL RS04910
gene id: 326424:FRAAL_RS04910
uniprot id: Q0RRM6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaD and TsaB. TsaE seems to play an indirect role in the t(6)A biosynthesis pathway, possibly in regulating the core enzymatic function of TsaD.

326424:FRAAL RS29365
gene id: 326424:FRAAL_RS29365
uniprot id: Q0RB38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

326424:FRAAL RS07865
gene id: 326424:FRAAL_RS07865
uniprot id: Q0RPQ5
names: Similarity
messages: Belongs to the carbamoyltransferase HypF family.

326424:FRAAL RS11430
gene id: 326424:FRAAL_RS11430
uniprot id: Q0RMI1
names: Subcellular Location Annotation
messages: Membrane

326424:FRAAL RS21705
gene id: 326424:FRAAL_RS21705
uniprot id: Q0RFX5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

326424:FRAAL RS30115
gene id: 326424:FRAAL_RS30115
uniprot id: Q0RU43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CbxX/CfxQ family.
messages: Cytoplasm

326424:FRAAL RS13805
gene id: 326424:FRAAL_RS13805
uniprot id: Q0RL01
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

326424:FRAAL RS07350
gene id: 326424:FRAAL_RS07350
uniprot id: Q0RQ26
names: Subcellular Location Annotation
messages: Membrane

326424:FRAAL RS27200
gene id: 326424:FRAAL_RS27200
uniprot id: Q0RCG7
names: Similarity
messages: Belongs to the peptidase S49 family.

326424:FRAAL RS14900
gene id: 326424:FRAAL_RS14900
uniprot id: Q0RK99
names: Similarity
messages: Belongs to the Rv1128c/1148c/1588c/1702c/1945/3466 family.

326424:FRAAL RS13200
gene id: 326424:FRAAL_RS13200
uniprot id: Q0RLD9
names: Function
names: Subcellular Location Annotation
messages: May play a structural or regulatory role in gas vesicle synthesis.
messages: Vesicle
messages: gas vesicle

326424:FRAAL RS25910
gene id: 326424:FRAAL_RS25910
uniprot id: Q0RD96
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

326424:FRAAL RS06055
gene id: 326424:FRAAL_RS06055
uniprot id: Q0RQX6
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

326424:FRAAL RS13095
gene id: 326424:FRAAL_RS13095
uniprot id: Q0RLG1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

326424:FRAAL RS05570
gene id: 326424:FRAAL_RS05570
uniprot id: Q0RR87
names: Similarity
messages: Belongs to the PGI/PMI family.

326424:FRAAL RS20915
gene id: 326424:FRAAL_RS20915
uniprot id: Q0RGF3
names: Similarity
messages: Belongs to the NtaA/SnaA/DszA monooxygenase family.

326424:FRAAL RS25220
gene id: 326424:FRAAL_RS25220
uniprot id: Q0RDP7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

326424:FRAAL RS26050
gene id: 326424:FRAAL_RS26050
uniprot id: Q0RD69
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

326424:FRAAL RS12685
gene id: 326424:FRAAL_RS12685
uniprot id: Q0RLQ3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

326424:FRAAL RS20055
gene id: 326424:FRAAL_RS20055
uniprot id: Q0RH06
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

326424:FRAAL RS11405
gene id: 326424:FRAAL_RS11405
uniprot id: Q0RMI6
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

326424:FRAAL RS07325
gene id: 326424:FRAAL_RS07325
uniprot id: Q0RQ32
names: Similarity
messages: Belongs to the peptidase S33 family.

326424:FRAAL RS22450
gene id: 326424:FRAAL_RS22450
uniprot id: Q0RFF6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

326424:FRAAL RS21075
gene id: 326424:FRAAL_RS21075
uniprot id: Q0RGB8
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

326424:FRAAL RS07605
gene id: 326424:FRAAL_RS07605
uniprot id: Q0RPW1
names: Similarity
messages: Belongs to the pirin family.

326424:FRAAL RS06745
gene id: 326424:FRAAL_RS06745
uniprot id: Q0RQG4
names: Function
names: Similarity
messages: Belongs to the TenA family.
messages: Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway.

326424:FRAAL RS25855
gene id: 326424:FRAAL_RS25855
uniprot id: Q0RDA8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.

326424:FRAAL RS24925
gene id: 326424:FRAAL_RS24925
uniprot id: Q0RDW2
names: Subcellular Location Annotation
messages: Membrane

326424:FRAAL RS11790
gene id: 326424:FRAAL_RS11790
uniprot id: Q0RMA0
names: Caution
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

326424:FRAAL RS28500
gene id: 326424:FRAAL_RS28500
uniprot id: Q0RBM7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

326424:FRAAL RS06845
gene id: 326424:FRAAL_RS06845
uniprot id: Q0RQD9
names: Subcellular Location Annotation
messages: Membrane

326424:FRAAL RS14680
gene id: 326424:FRAAL_RS14680
uniprot id: Q0RKF0
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

326424:FRAAL RS29240
gene id: 326424:FRAAL_RS29240
uniprot id: Q0RB68
names: Function
names: Similarity
messages: Belongs to the trehalose phosphatase family.
messages: Removes the phosphate from trehalose 6-phosphate to produce free trehalose.

326424:FRAAL RS06165
gene id: 326424:FRAAL_RS06165
uniprot id: Q0RQU9
names: PTM
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.
messages: Carbamylation allows a single lysine to coordinate two divalent metal cations.

326424:FRAAL RS13365
gene id: 326424:FRAAL_RS13365
uniprot id: Q0RLA5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

326424:FRAAL RS19995
gene id: 326424:FRAAL_RS19995
uniprot id: Q0RH20
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.

326424:FRAAL RS02570
gene id: 326424:FRAAL_RS02570
uniprot id: Q0RT34
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

326424:FRAAL RS14615
gene id: 326424:FRAAL_RS14615
uniprot id: Q0RKG4
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

326424:FRAAL RS19640
gene id: 326424:FRAAL_RS19640
uniprot id: Q0RH97
names: Subcellular Location Annotation
messages: Cytoplasm

326424:FRAAL RS17290
gene id: 326424:FRAAL_RS17290
uniprot id: Q0RIS7
names: Similarity
messages: Belongs to the AHA1 family.

326424:FRAAL RS27055
gene id: 326424:FRAAL_RS27055
uniprot id: Q0RCJ7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.
messages: Cytoplasm
messages: Monomer.

326424:FRAAL RS22830
gene id: 326424:FRAAL_RS22830
uniprot id: Q0RF82
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

326424:FRAAL RS27275
gene id: 326424:FRAAL_RS27275
uniprot id: Q0RCF3
names: Subcellular Location Annotation
messages: Membrane

326424:FRAAL RS00460
gene id: 326424:FRAAL_RS00460
uniprot id: Q0RUG3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

326424:FRAAL RS16785
gene id: 326424:FRAAL_RS16785
uniprot id: Q0RJ34
names: Function
names: Similarity
messages: Belongs to the UPF0677 family.
messages: Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity.

326424:FRAAL RS09325
gene id: 326424:FRAAL_RS09325
uniprot id: Q0RNV0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glutaminase PdxT/SNO family.
messages: Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
messages: In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer.

326424:FRAAL RS21670
gene id: 326424:FRAAL_RS21670
uniprot id: Q0RFY2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

326424:FRAAL RS28445
gene id: 326424:FRAAL_RS28445
uniprot id: Q0RBN8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).

326424:FRAAL RS22165
gene id: 326424:FRAAL_RS22165
uniprot id: Q0RFL9
names: Similarity
messages: Belongs to the class-II DAHP synthase family.

326424:FRAAL RS25250
gene id: 326424:FRAAL_RS25250
uniprot id: Q0RDP2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

326424:FRAAL RS30180
gene id: 326424:FRAAL_RS30180
uniprot id: Q0RSL7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

326424:FRAAL RS16090
gene id: 326424:FRAAL_RS16090
uniprot id: Q0RJI7
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

326424:FRAAL RS08265
gene id: 326424:FRAAL_RS08265
uniprot id: Q0RPH3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

326424:FRAAL RS22175
gene id: 326424:FRAAL_RS22175
uniprot id: Q0RFL7
names: Cofactor
names: Function
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Exonuclease that cleaves single-stranded 3' overhangs of double-stranded RNA.
messages: Homodimer.

326424:FRAAL RS25615
gene id: 326424:FRAAL_RS25615
uniprot id: Q0RDG1
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

326424:FRAAL RS19910
gene id: 326424:FRAAL_RS19910
uniprot id: Q0RH38
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.

326424:FRAAL RS23785
gene id: 326424:FRAAL_RS23785
uniprot id: Q0REL4
names: Similarity
messages: Belongs to the peptidase S33 family.

326424:FRAAL RS09225
gene id: 326424:FRAAL_RS09225
uniprot id: Q0RNW8
names: Subcellular Location Annotation
messages: Membrane

326424:FRAAL RS29120
gene id: 326424:FRAAL_RS29120
uniprot id: Q0RB92
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate, the first step in the de novo biosynthesis of NAD(+).
messages: Cytoplasm

326424:FRAAL RS04375
gene id: 326424:FRAAL_RS04375
uniprot id: Q0RRY3
names: Function
messages: Catalyzes the reduction of sulfite to sulfide, a step in the biosynthesis of sulfur-containing amino acids and cofactors.

326424:FRAAL RS16600
gene id: 326424:FRAAL_RS16600
uniprot id: Q0RJ75
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

326424:FRAAL RS15525
gene id: 326424:FRAAL_RS15525
uniprot id: Q0RJW5
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

326424:FRAAL RS18290
gene id: 326424:FRAAL_RS18290
uniprot id: Q0RI44
names: Function
names: Similarity
messages: Belongs to the RecD family. RecD-like subfamily.
messages: DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity.

326424:FRAAL RS14395
gene id: 326424:FRAAL_RS14395
uniprot id: Q0RKL9
names: Function
names: Similarity
messages: ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
messages: Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.

326424:FRAAL RS11020
gene id: 326424:FRAAL_RS11020
uniprot id: Q0RMT1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

326424:FRAAL RS23485
gene id: 326424:FRAAL_RS23485
uniprot id: Q0RET7
names: Similarity
messages: Belongs to the NtaA/SnaA/DszA monooxygenase family.

326424:FRAAL RS28020
gene id: 326424:FRAAL_RS28020
uniprot id: Q0RBY6
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

326424:FRAAL RS29835
gene id: 326424:FRAAL_RS29835
uniprot id: Q0RAT5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
messages: Cell membrane
messages: Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD).

326424:FRAAL RS13565
gene id: 326424:FRAAL_RS13565
uniprot id: Q0RL56
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

326424:FRAAL RS04650
gene id: 326424:FRAAL_RS04650
uniprot id: Q0RRS9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

326424:FRAAL RS02585
gene id: 326424:FRAAL_RS02585
uniprot id: Q0RT30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

326424:FRAAL RS17920
gene id: 326424:FRAAL_RS17920
uniprot id: Q0RID3
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

326424:FRAAL RS18720
gene id: 326424:FRAAL_RS18720
uniprot id: Q0RHU8
names: Cofactor
names: Similarity
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.

326424:FRAAL RS19965
gene id: 326424:FRAAL_RS19965
uniprot id: Q0RH26
names: Activity Regulation
names: Caution
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

326424:FRAAL RS20495
gene id: 326424:FRAAL_RS20495
uniprot id: Q0RGP1
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

326424:FRAAL RS07355
gene id: 326424:FRAAL_RS07355
uniprot id: Q0RQ25
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

326424:FRAAL RS04780
gene id: 326424:FRAAL_RS04780
uniprot id: Q0RRQ3
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

326424:FRAAL RS29945
gene id: 326424:FRAAL_RS29945
uniprot id: Q0RAR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 87 family.
messages: Membrane

326424:FRAAL RS00905
gene id: 326424:FRAAL_RS00905
uniprot id: Q0RU69
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

326424:FRAAL RS09560
gene id: 326424:FRAAL_RS09560
uniprot id: Q0RNP9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

326424:FRAAL RS09885
gene id: 326424:FRAAL_RS09885
uniprot id: Q0RNH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

326424:FRAAL RS08695
gene id: 326424:FRAAL_RS08695
uniprot id: Q0RP79
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

326424:FRAAL RS16905
gene id: 326424:FRAAL_RS16905
uniprot id: Q0RJ07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

326424:FRAAL RS20985
gene id: 326424:FRAAL_RS20985
uniprot id: Q0RGD8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Membrane

326424:FRAAL RS12635
gene id: 326424:FRAAL_RS12635
uniprot id: Q0RLR5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

326424:FRAAL RS01630
gene id: 326424:FRAAL_RS01630
uniprot id: Q0RTQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

326424:FRAAL RS28320
gene id: 326424:FRAAL_RS28320
uniprot id: Q0RBR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SsgA family.
messages: Cell septum

326424:FRAAL RS12655
gene id: 326424:FRAAL_RS12655
uniprot id: Q0RLR1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

326424:FRAAL RS04685
gene id: 326424:FRAAL_RS04685
uniprot id: Q0RRS2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

326424:FRAAL RS14225
gene id: 326424:FRAAL_RS14225
uniprot id: Q0RKQ8
names: Cofactor
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.
messages: Binds 3 [4Fe-4S] clusters per subunit.

326424:FRAAL RS06410
gene id: 326424:FRAAL_RS06410
uniprot id: Q0RQP6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

326424:FRAAL RS09320
gene id: 326424:FRAAL_RS09320
uniprot id: Q0RNV1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PdxS/SNZ family.
messages: Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
messages: In the presence of PdxT, forms a dodecamer of heterodimers.

326424:FRAAL RS07025
gene id: 326424:FRAAL_RS07025
uniprot id: Q0RQ96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

326424:FRAAL RS08020
gene id: 326424:FRAAL_RS08020
uniprot id: Q0RPM3
names: Similarity
messages: Belongs to the peptidase M1 family.

326424:FRAAL RS04885
gene id: 326424:FRAAL_RS04885
uniprot id: Q0RRN2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

326424:FRAAL RS04810
gene id: 326424:FRAAL_RS04810
uniprot id: Q0RRP7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

326424:FRAAL RS13835
gene id: 326424:FRAAL_RS13835
uniprot id: Q0RKZ4
names: Similarity
messages: Belongs to the catalase family.

326424:FRAAL RS13385
gene id: 326424:FRAAL_RS13385
uniprot id: Q0RLA0
names: Similarity
messages: Belongs to the cytochrome P450 family.

326424:FRAAL RS04925
gene id: 326424:FRAAL_RS04925
uniprot id: Q0RRM3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
messages: Belongs to the azoreductase type 1 family.
messages: Binds 1 FMN per subunit.
messages: Homodimer.
messages: Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones.

326424:FRAAL RS21605
gene id: 326424:FRAAL_RS21605
uniprot id: Q0RFZ5
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

326424:FRAAL RS29370
gene id: 326424:FRAAL_RS29370
uniprot id: Q0RB37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

326424:FRAAL RS29410
gene id: 326424:FRAAL_RS29410
uniprot id: Q0RB29
names: Similarity
messages: Belongs to the FPG family.

326424:FRAAL RS15115
gene id: 326424:FRAAL_RS15115
uniprot id: Q0RK51
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

326424:FRAAL RS15305
gene id: 326424:FRAAL_RS15305
uniprot id: Q0RK11
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

326424:FRAAL RS09900
gene id: 326424:FRAAL_RS09900
uniprot id: Q0RNH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sbp family.
messages: Cell membrane

326424:FRAAL RS05335
gene id: 326424:FRAAL_RS05335
uniprot id: Q0RRD6
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

326424:FRAAL RS10315
gene id: 326424:FRAAL_RS10315
uniprot id: Q0RN86
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

326424:FRAAL RS19415
gene id: 326424:FRAAL_RS19415
uniprot id: Q0RHE7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

326424:FRAAL RS25145
gene id: 326424:FRAAL_RS25145
uniprot id: Q0RDR2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

326424:FRAAL RS26715
gene id: 326424:FRAAL_RS26715
uniprot id: Q0RCS5
names: Cofactor
names: Function
messages: Binds 1 [3Fe-4S] cluster.
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

326424:FRAAL RS24895
gene id: 326424:FRAAL_RS24895
uniprot id: Q0RDW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

326424:FRAAL RS23795
gene id: 326424:FRAAL_RS23795
uniprot id: Q0REL2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

326424:FRAAL RS16505
gene id: 326424:FRAAL_RS16505
uniprot id: Q0RJ96
names: Cofactor
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Binds 1 zinc ion per subunit. The zinc ion is important for the structural integrity of the protein.

326424:FRAAL RS29785
gene id: 326424:FRAAL_RS29785
uniprot id: Q0RAU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

326424:FRAAL RS13965
gene id: 326424:FRAAL_RS13965
uniprot id: Q0RKW5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterotetramer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits of ACCase subunit beta/alpha.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA (By similarity).
messages: Cytoplasm
messages: In the C-terminal section; belongs to the AccA family.
messages: In the N-terminal section; belongs to the AccD/PCCB family.

326424:FRAAL RS02615
gene id: 326424:FRAAL_RS02615
uniprot id: Q0RT24
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids lysine, threonine, isoleucine and methionine.

326424:FRAAL RS24565
gene id: 326424:FRAAL_RS24565
uniprot id: Q0RE36
names: Similarity
messages: Belongs to the asparagine synthetase family.

326424:FRAAL RS07680
gene id: 326424:FRAAL_RS07680
uniprot id: Q0RPU4
names: Similarity
messages: Belongs to the glutathione peroxidase family.

326424:FRAAL RS11450
gene id: 326424:FRAAL_RS11450
uniprot id: Q0RMH7
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

326424:FRAAL RS00900
gene id: 326424:FRAAL_RS00900
uniprot id: Q0RU70
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

326424:FRAAL RS22510
gene id: 326424:FRAAL_RS22510
uniprot id: Q0RFE4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Cytoplasm
messages: Oligomer of 12 subunits arranged in the form of two hexagons.

326424:FRAAL RS07145
gene id: 326424:FRAAL_RS07145
uniprot id: Q0RQ69
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

326424:FRAAL RS06895
gene id: 326424:FRAAL_RS06895
uniprot id: Q0RQC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

326424:FRAAL RS28280
gene id: 326424:FRAAL_RS28280
uniprot id: Q0RBS5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

326424:FRAAL RS07840
gene id: 326424:FRAAL_RS07840
uniprot id: Q0RPR1
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

326424:FRAAL RS25730
gene id: 326424:FRAAL_RS25730
uniprot id: Q0RDD4
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

326424:FRAAL RS27910
gene id: 326424:FRAAL_RS27910
uniprot id: Q0RC11
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

326424:FRAAL RS22375
gene id: 326424:FRAAL_RS22375
uniprot id: Q0RFH3
names: Similarity
messages: Belongs to the shaker potassium channel beta subunit family.

326424:FRAAL RS16135
gene id: 326424:FRAAL_RS16135
uniprot id: Q0RJH6
names: Similarity
messages: Belongs to the ComB family.

326424:FRAAL RS24320
gene id: 326424:FRAAL_RS24320
uniprot id: Q0RE94
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

326424:FRAAL RS08975
gene id: 326424:FRAAL_RS08975
uniprot id: Q0RP21
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.

326424:FRAAL RS04665
gene id: 326424:FRAAL_RS04665
uniprot id: Q0RRS6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

326424:FRAAL RS26490
gene id: 326424:FRAAL_RS26490
uniprot id: Q0RCX7
names: Similarity
messages: Belongs to the HIBADH-related family.

326424:FRAAL RS06555
gene id: 326424:FRAAL_RS06555
uniprot id: Q0RQL3
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

326424:FRAAL RS30060
gene id: 326424:FRAAL_RS30060
uniprot id: Q0RAN7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

326424:FRAAL RS29575
gene id: 326424:FRAAL_RS29575
uniprot id: Q0RAZ1
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

326424:FRAAL RS08840
gene id: 326424:FRAAL_RS08840
uniprot id: Q0RP48
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

326424:FRAAL RS13605
gene id: 326424:FRAAL_RS13605
uniprot id: Q0RL47
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

326424:FRAAL RS01970
gene id: 326424:FRAAL_RS01970
uniprot id: Q0RTI2
names: Subcellular Location Annotation
messages: Membrane

326424:FRAAL RS02320
gene id: 326424:FRAAL_RS02320
uniprot id: Q0RT91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S33 family.
messages: Cytoplasm

326424:FRAAL RS01510
gene id: 326424:FRAAL_RS01510
uniprot id: Q0RTT1
names: Subcellular Location Annotation
messages: Membrane

326424:FRAAL RS20045
gene id: 326424:FRAAL_RS20045
uniprot id: Q0RH09
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

326424:FRAAL RS17735
gene id: 326424:FRAAL_RS17735
uniprot id: Q0RIH8
names: Subcellular Location Annotation
messages: Membrane

326424:FRAAL RS25185
gene id: 326424:FRAAL_RS25185
uniprot id: Q0RDQ4
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

326424:FRAAL RS21530
gene id: 326424:FRAAL_RS21530
uniprot id: Q0RG14
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

326424:FRAAL RS21805
gene id: 326424:FRAAL_RS21805
uniprot id: Q0RFU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

326424:FRAAL RS26605
gene id: 326424:FRAAL_RS26605
uniprot id: Q0RCV1
names: Similarity
messages: Belongs to the LOG family.

326424:FRAAL RS28035
gene id: 326424:FRAAL_RS28035
uniprot id: Q0RBY3
names: Similarity
messages: Belongs to the lysine N(6)-hydroxylase/L-ornithine N(5)-oxygenase family.

326424:FRAAL RS23810
gene id: 326424:FRAAL_RS23810
uniprot id: Q0REK8
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

326424:FRAAL RS22490
gene id: 326424:FRAAL_RS22490
uniprot id: Q0RFE8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

326424:FRAAL RS25205
gene id: 326424:FRAAL_RS25205
uniprot id: Q0RDQ0
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

326424:FRAAL RS22585
gene id: 326424:FRAAL_RS22585
uniprot id: Q0RFC7
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

326424:FRAAL RS04225
gene id: 326424:FRAAL_RS04225
uniprot id: Q0RS16
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

326424:FRAAL RS04715
gene id: 326424:FRAAL_RS04715
uniprot id: Q0RRR6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity).

326424:FRAAL RS11150
gene id: 326424:FRAAL_RS11150
uniprot id: Q0RMQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

326424:FRAAL RS29545
gene id: 326424:FRAAL_RS29545
uniprot id: Q0RB00
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

326424:FRAAL RS18830
gene id: 326424:FRAAL_RS18830
uniprot id: Q0RHS2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

326424:FRAAL RS17180
gene id: 326424:FRAAL_RS17180
uniprot id: Q0RIU9
names: Similarity
messages: Belongs to the cytochrome P450 family.

326424:FRAAL RS19065
gene id: 326424:FRAAL_RS19065
uniprot id: Q0RHM2
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

326424:FRAAL RS17955
gene id: 326424:FRAAL_RS17955
uniprot id: Q0RIC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

326424:FRAAL RS08305
gene id: 326424:FRAAL_RS08305
uniprot id: Q0RPG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Membrane

326424:FRAAL RS04820
gene id: 326424:FRAAL_RS04820
uniprot id: Q0RRP5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

326424:FRAAL RS26260
gene id: 326424:FRAAL_RS26260
uniprot id: Q0RD23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0182 family.
messages: Cell membrane

326424:FRAAL RS29050
gene id: 326424:FRAAL_RS29050
uniprot id: Q0RBA8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.

326424:FRAAL RS09630
gene id: 326424:FRAAL_RS09630
uniprot id: Q0RNN4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SepF family.
messages: Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

326424:FRAAL RS21300
gene id: 326424:FRAAL_RS21300
uniprot id: Q0RG66
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

326424:FRAAL RS29880
gene id: 326424:FRAAL_RS29880
uniprot id: Q0RAS6
names: Function
names: Similarity
messages: Belongs to the EgtB family.
messages: Catalyzes the oxidative sulfurization of hercynine (N-alpha,N-alpha,N-alpha-trimethyl-L-histidine) into hercynyl-gamma-L-glutamyl-L-cysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine.

326424:FRAAL RS09230
gene id: 326424:FRAAL_RS09230
uniprot id: Q0RNW7
names: Similarity
messages: Belongs to the band 7/mec-2 family.

326424:FRAAL RS22170
gene id: 326424:FRAAL_RS22170
uniprot id: Q0RFL8
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
messages: Cytoplasm
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Non-allosteric.

326424:FRAAL RS25375
gene id: 326424:FRAAL_RS25375
uniprot id: Q0RDK9
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

326424:FRAAL RS25525
gene id: 326424:FRAAL_RS25525
uniprot id: Q0RDH8
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

326424:FRAAL RS15670
gene id: 326424:FRAAL_RS15670
uniprot id: Q0RJT1
names: Subcellular Location Annotation
messages: Membrane

326424:FRAAL RS17310
gene id: 326424:FRAAL_RS17310
uniprot id: Q0RIS3
names: Subcellular Location Annotation
messages: Membrane

326424:FRAAL RS02650
gene id: 326424:FRAAL_RS02650
uniprot id: Q0RT17
names: Similarity
messages: Belongs to the DnaX/STICHEL family.

326424:FRAAL RS01395
gene id: 326424:FRAAL_RS01395
uniprot id: Q0RTV6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

326424:FRAAL RS25230
gene id: 326424:FRAAL_RS25230
uniprot id: Q0RDP5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

326424:FRAAL RS06970
gene id: 326424:FRAAL_RS06970
uniprot id: Q0RQA8
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

326424:FRAAL RS24900
gene id: 326424:FRAAL_RS24900
uniprot id: Q0RDW7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase Y family.
messages: Cell membrane
messages: Endoribonuclease that initiates mRNA decay.

326424:FRAAL RS24435
gene id: 326424:FRAAL_RS24435
uniprot id: Q0RE66
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 2 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

326424:FRAAL RS19300
gene id: 326424:FRAAL_RS19300
uniprot id: Q0RHH2
names: Similarity
names: Subunit
messages: Belongs to the aldehyde dehydrogenase family.
messages: Homotetramer.

326424:FRAAL RS04700
gene id: 326424:FRAAL_RS04700
uniprot id: Q0RRR9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

326424:FRAAL RS02195
gene id: 326424:FRAAL_RS02195
uniprot id: Q0RTC1
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

326424:FRAAL RS22545
gene id: 326424:FRAAL_RS22545
uniprot id: Q0RFD5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

326424:FRAAL RS04305
gene id: 326424:FRAAL_RS04305
uniprot id: Q0RRZ7
names: Subcellular Location Annotation
messages: Membrane

326424:FRAAL RS07385
gene id: 326424:FRAAL_RS07385
uniprot id: Q0RQ19
names: Similarity
messages: Belongs to the pirin family.

326424:FRAAL RS24020
gene id: 326424:FRAAL_RS24020
uniprot id: Q0REG3
names: Similarity
messages: Belongs to the Nudix hydrolase family.

326424:FRAAL RS23875
gene id: 326424:FRAAL_RS23875
uniprot id: Q0REJ5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the malate synthase family. GlcB subfamily.
messages: Cytoplasm
messages: Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

326424:FRAAL RS21675
gene id: 326424:FRAAL_RS21675
uniprot id: Q0RFY1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

326424:FRAAL RS10540
gene id: 326424:FRAAL_RS10540
uniprot id: Q0RN32
names: Subunit
messages: Homodimer.

326424:FRAAL RS10460
gene id: 326424:FRAAL_RS10460
uniprot id: Q0RN51
names: Similarity
names: Subunit
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family.
messages: Heterodimer of a large and a small subunit.

326424:FRAAL RS25065
gene id: 326424:FRAAL_RS25065
uniprot id: Q0RDT0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

326424:FRAAL RS30035
gene id: 326424:FRAAL_RS30035
uniprot id: Q0RAP2
names: Similarity
messages: Belongs to the ParB family.

326424:FRAAL RS05205
gene id: 326424:FRAAL_RS05205
uniprot id: Q0RRG3
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Homodimer.

326424:FRAAL RS24905
gene id: 326424:FRAAL_RS24905
uniprot id: Q0RDW6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

326424:FRAAL RS16620
gene id: 326424:FRAAL_RS16620
uniprot id: Q0RJ70
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

326424:FRAAL RS06865
gene id: 326424:FRAAL_RS06865
uniprot id: Q0RQD5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

326424:FRAAL RS26485
gene id: 326424:FRAAL_RS26485
uniprot id: Q0RCX8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

326424:FRAAL RS16765
gene id: 326424:FRAAL_RS16765
uniprot id: Q0RJ42
names: Subcellular Location Annotation
messages: Membrane

326424:FRAAL RS09590
gene id: 326424:FRAAL_RS09590
uniprot id: Q0RNP3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

326424:FRAAL RS18870
gene id: 326424:FRAAL_RS18870
uniprot id: Q0RHR3
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

326424:FRAAL RS25015
gene id: 326424:FRAAL_RS25015
uniprot id: Q0RDU0
names: Similarity
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Homodimer.

326424:FRAAL RS04970
gene id: 326424:FRAAL_RS04970
uniprot id: Q0RRL4
names: Similarity
messages: Belongs to the IMPDH/GMPR family.

326424:FRAAL RS29740
gene id: 326424:FRAAL_RS29740
uniprot id: Q0RAV7
names: Function
names: Similarity
messages: Belongs to the NifD/NifK/NifE/NifN family.
messages: This protein may play a role in the biosynthesis of the prosthetic group of nitrogenase (FeMo cofactor).

326424:FRAAL RS27905
gene id: 326424:FRAAL_RS27905
uniprot id: Q0RC12
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

326424:FRAAL RS25850
gene id: 326424:FRAAL_RS25850
uniprot id: Q0RDA9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

326424:FRAAL RS00490
gene id: 326424:FRAAL_RS00490
uniprot id: Q0RUF8
names: Similarity
messages: Belongs to the DNA photolyase family.

326424:FRAAL RS21665
gene id: 326424:FRAAL_RS21665
uniprot id: Q0RFY3
names: Similarity
messages: Belongs to the glutamate synthase family.

326424:FRAAL RS03985
gene id: 326424:FRAAL_RS03985
uniprot id: Q0RS68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDT1 family.
messages: Membrane

326424:FRAAL RS21245
gene id: 326424:FRAAL_RS21245
uniprot id: Q0RG78
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

326424:FRAAL RS15740
gene id: 326424:FRAAL_RS15740
uniprot id: Q0RJR7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

326424:FRAAL RS06535
gene id: 326424:FRAAL_RS06535
uniprot id: Q0RQL8
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

326424:FRAAL RS12480
gene id: 326424:FRAAL_RS12480
uniprot id: Q0RLU7
names: Subcellular Location Annotation
messages: Membrane

326424:FRAAL RS06355
gene id: 326424:FRAAL_RS06355
uniprot id: Q0RQQ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Homotetramer.

326424:FRAAL RS28570
gene id: 326424:FRAAL_RS28570
uniprot id: Q0RBL3
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

326424:FRAAL RS00925
gene id: 326424:FRAAL_RS00925
uniprot id: Q0RU65
names: Similarity
messages: Belongs to the cytochrome P450 family.

326424:FRAAL RS13840
gene id: 326424:FRAAL_RS13840
uniprot id: Q0RKZ3
names: Similarity
messages: Belongs to the Fur family.

326424:FRAAL RS04790
gene id: 326424:FRAAL_RS04790
uniprot id: Q0RRQ1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

326424:FRAAL RS00055
gene id: 326424:FRAAL_RS00055
uniprot id: Q0RUQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

326424:FRAAL RS04805
gene id: 326424:FRAAL_RS04805
uniprot id: Q0RRP8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

326424:FRAAL RS08665
gene id: 326424:FRAAL_RS08665
uniprot id: Q0RP86
names: Subcellular Location Annotation
messages: Membrane

326424:FRAAL RS05810
gene id: 326424:FRAAL_RS05810
uniprot id: Q0RR37
names: Subcellular Location Annotation
messages: Membrane

326424:FRAAL RS00940
gene id: 326424:FRAAL_RS00940
uniprot id: Q0RU61
names: Subcellular Location Annotation
messages: Membrane

326424:FRAAL RS24690
gene id: 326424:FRAAL_RS24690
uniprot id: Q0RE11
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

326424:FRAAL RS04500
gene id: 326424:FRAAL_RS04500
uniprot id: Q0RRV7
names: Subcellular Location Annotation
messages: Membrane

326424:FRAAL RS04425
gene id: 326424:FRAAL_RS04425
uniprot id: Q0RRX3
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

326424:FRAAL RS19870
gene id: 326424:FRAAL_RS19870
uniprot id: Q0RH48
names: Subcellular Location Annotation
messages: Membrane

326424:FRAAL RS25255
gene id: 326424:FRAAL_RS25255
uniprot id: Q0RDP1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

326424:FRAAL RS14705
gene id: 326424:FRAAL_RS14705
uniprot id: Q0RKE4
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

326424:FRAAL RS06645
gene id: 326424:FRAAL_RS06645
uniprot id: Q0RQJ3
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: May be specifically involved in the processing, transport, and/or maturation of the MADH beta-subunit.
messages: Membrane

326424:FRAAL RS03995
gene id: 326424:FRAAL_RS03995
uniprot id: Q0RS65
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

326424:FRAAL RS22220
gene id: 326424:FRAAL_RS22220
uniprot id: Q0RFK8
names: Similarity
messages: Belongs to the arsA ATPase family.

326424:FRAAL RS04480
gene id: 326424:FRAAL_RS04480
uniprot id: Q0RRW1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

326424:FRAAL RS16945
gene id: 326424:FRAAL_RS16945
uniprot id: Q0RIZ9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

326424:FRAAL RS00620
gene id: 326424:FRAAL_RS00620
uniprot id: Q0RUC9
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

326424:FRAAL RS05785
gene id: 326424:FRAAL_RS05785
uniprot id: Q0RR42
names: Subcellular Location Annotation
messages: Membrane

326424:FRAAL RS20540
gene id: 326424:FRAAL_RS20540
uniprot id: Q0RGN3
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

326424:FRAAL RS30285
gene id: 326424:FRAAL_RS30285
uniprot id: Q0RPE1
names: Similarity
messages: Belongs to the ice-binding protein family.

326424:FRAAL RS25710
gene id: 326424:FRAAL_RS25710
uniprot id: Q0RDD9
names: Similarity
messages: Belongs to the UPF0045 family.

326424:FRAAL RS16685
gene id: 326424:FRAAL_RS16685
uniprot id: Q0RJ58
names: Subcellular Location Annotation
messages: Membrane

326424:FRAAL RS06060
gene id: 326424:FRAAL_RS06060
uniprot id: Q0RQX5
names: Subcellular Location Annotation
messages: Cytoplasm

326424:FRAAL RS17965
gene id: 326424:FRAAL_RS17965
uniprot id: Q0RIC4
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

326424:FRAAL RS03875
gene id: 326424:FRAAL_RS03875
uniprot id: Q0RS91
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DtxR/MntR family.
messages: Cytoplasm
messages: Homodimer.

326424:FRAAL RS07810
gene id: 326424:FRAAL_RS07810
uniprot id: Q0RPR8
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

326424:FRAAL RS06080
gene id: 326424:FRAAL_RS06080
uniprot id: Q0RQX1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

326424:FRAAL RS21190
gene id: 326424:FRAAL_RS21190
uniprot id: Q0RG92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Belongs to the glycosyltransferase 2 family.
messages: Membrane

326424:FRAAL RS26020
gene id: 326424:FRAAL_RS26020
uniprot id: Q0RD75
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

326424:FRAAL RS26725
gene id: 326424:FRAAL_RS26725
uniprot id: Q0RCS3
names: Similarity
messages: Belongs to the UPF0162 family.

326424:FRAAL RS14220
gene id: 326424:FRAAL_RS14220
uniprot id: Q0RKR0
names: Function
names: Similarity
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.

326424:FRAAL RS03860
gene id: 326424:FRAAL_RS03860
uniprot id: Q0RS94
names: Similarity
messages: Belongs to the P(II) protein family.

326424:FRAAL RS04825
gene id: 326424:FRAAL_RS04825
uniprot id: Q0RRP4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

326424:FRAAL RS29675
gene id: 326424:FRAAL_RS29675
uniprot id: Q0RAX0
names: Cofactor
names: Function
messages: Binds 1 [3Fe-4S] cluster.
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

326424:FRAAL RS09605
gene id: 326424:FRAAL_RS09605
uniprot id: Q0RNP0
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

326424:FRAAL RS18795
gene id: 326424:FRAAL_RS18795
uniprot id: Q0RHT0
names: Similarity
messages: Belongs to the Nudix hydrolase family.

326424:FRAAL RS19930
gene id: 326424:FRAAL_RS19930
uniprot id: Q0RH33
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.

326424:FRAAL RS04145
gene id: 326424:FRAAL_RS04145
uniprot id: Q0RS34
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

326424:FRAAL RS09940
gene id: 326424:FRAAL_RS09940
uniprot id: Q0RNG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

326424:FRAAL RS25920
gene id: 326424:FRAAL_RS25920
uniprot id: Q0RD94
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

326424:FRAAL RS02925
gene id: 326424:FRAAL_RS02925
uniprot id: Q0RSW0
names: Cofactor
names: Similarity
messages: Belongs to the fatty acid desaturase type 2 family.
messages: Binds 2 iron ions per subunit.

326424:FRAAL RS04460
gene id: 326424:FRAAL_RS04460
uniprot id: Q0RRW5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

326424:FRAAL RS15195
gene id: 326424:FRAAL_RS15195
uniprot id: Q0RK33
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

326424:FRAAL RS09825
gene id: 326424:FRAAL_RS09825
uniprot id: Q0RNI8
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

326424:FRAAL RS04680
gene id: 326424:FRAAL_RS04680
uniprot id: Q0RRS3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

326424:FRAAL RS29735
gene id: 326424:FRAAL_RS29735
uniprot id: Q0RAV8
names: Similarity
messages: Belongs to the NifD/NifK/NifE/NifN family.

326424:FRAAL RS12300
gene id: 326424:FRAAL_RS12300
uniprot id: Q0RLY6
names: Similarity
messages: Belongs to the AHA1 family.

326424:FRAAL RS18670
gene id: 326424:FRAAL_RS18670
uniprot id: Q0RHW2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

326424:FRAAL RS19475
gene id: 326424:FRAAL_RS19475
uniprot id: Q0RHD5
names: Similarity
messages: Belongs to the NtaA/SnaA/DszA monooxygenase family.

326424:FRAAL RS22415
gene id: 326424:FRAAL_RS22415
uniprot id: Q0RFG3
names: Function
names: Similarity
messages: Belongs to the CobT family.
messages: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).

326424:FRAAL RS26745
gene id: 326424:FRAAL_RS26745
uniprot id: Q0RCR9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the MshB deacetylase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deacetylation of 1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway.

326424:FRAAL RS09345
gene id: 326424:FRAAL_RS09345
uniprot id: Q0RNU6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

326424:FRAAL RS02860
gene id: 326424:FRAAL_RS02860
uniprot id: Q0RSX4
names: Similarity
messages: Belongs to the glycosyl hydrolase 26 family.

326424:FRAAL RS29635
gene id: 326424:FRAAL_RS29635
uniprot id: Q0RAX8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

326424:FRAAL RS05410
gene id: 326424:FRAAL_RS05410
uniprot id: Q0RRC1
names: Similarity
messages: Belongs to the ABC transporter superfamily.

326424:FRAAL RS27175
gene id: 326424:FRAAL_RS27175
uniprot id: Q0RCH2
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 5 (UDGb) family.

326424:FRAAL RS14410
gene id: 326424:FRAAL_RS14410
uniprot id: Q0RKL6
names: Cofactor
names: Similarity
messages: Belongs to the monomeric-type IDH family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

326424:FRAAL RS20935
gene id: 326424:FRAAL_RS20935
uniprot id: Q0RGE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

326424:FRAAL RS07935
gene id: 326424:FRAAL_RS07935
uniprot id: Q0RPP0
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

326424:FRAAL RS17885
gene id: 326424:FRAAL_RS17885
uniprot id: Q0RIE3
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

326424:FRAAL RS06795
gene id: 326424:FRAAL_RS06795
uniprot id: Q0RQF3
names: Similarity
messages: Belongs to the 6-phosphogluconate dehydrogenase family.

326424:FRAAL RS04230
gene id: 326424:FRAAL_RS04230
uniprot id: Q0RS15
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

326424:FRAAL RS01345
gene id: 326424:FRAAL_RS01345
uniprot id: Q0RTW8
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Belongs to the peroxiredoxin family. Prx6 subfamily.

326424:FRAAL RS29745
gene id: 326424:FRAAL_RS29745
uniprot id: Q0RAV6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NifD/NifK/NifE/NifN family.
messages: Binds 1 [8Fe-7S] cluster per heterodimer.
messages: Tetramer of two alpha and two beta chains. Forms complex with the iron protein (nitrogenase component 2).
messages: This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation.

326424:FRAAL RS11000
gene id: 326424:FRAAL_RS11000
uniprot id: Q0RMT6
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

326424:FRAAL RS01480
gene id: 326424:FRAAL_RS01480
uniprot id: Q0RTT8
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

326424:FRAAL RS27810
gene id: 326424:FRAAL_RS27810
uniprot id: Q0RC32
names: Subcellular Location Annotation
messages: Membrane

326424:FRAAL RS29085
gene id: 326424:FRAAL_RS29085
uniprot id: Q0RBA0
names: Similarity
messages: Belongs to the GARS family.

326424:FRAAL RS01840
gene id: 326424:FRAAL_RS01840
uniprot id: Q0RTL3
names: Similarity
messages: Belongs to the DEAD box helicase family.

326424:FRAAL RS22695
gene id: 326424:FRAAL_RS22695
uniprot id: Q0RFA9
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

326424:FRAAL RS26440
gene id: 326424:FRAAL_RS26440
uniprot id: Q0RCY7
names: Subcellular Location Annotation
messages: Membrane

326424:FRAAL RS05970
gene id: 326424:FRAAL_RS05970
uniprot id: Q0RR00
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

326424:FRAAL RS22115
gene id: 326424:FRAAL_RS22115
uniprot id: Q0RFM9
names: Subcellular Location Annotation
messages: Membrane

326424:FRAAL RS21235
gene id: 326424:FRAAL_RS21235
uniprot id: Q0RG80
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

326424:FRAAL RS13345
gene id: 326424:FRAAL_RS13345
uniprot id: Q0RLA9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

326424:FRAAL RS16565
gene id: 326424:FRAAL_RS16565
uniprot id: Q0RJ82
names: Subcellular Location Annotation
messages: Membrane

326424:FRAAL RS21940
gene id: 326424:FRAAL_RS21940
uniprot id: Q0RFR6
names: Subcellular Location Annotation
messages: Membrane

326424:FRAAL RS12185
gene id: 326424:FRAAL_RS12185
uniprot id: Q0RM11
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

326424:FRAAL RS06805
gene id: 326424:FRAAL_RS06805
uniprot id: Q0RQF1
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

326424:FRAAL RS20455
gene id: 326424:FRAAL_RS20455
uniprot id: Q0RGQ6
names: Similarity
messages: Belongs to the clavaminate synthase family.

326424:FRAAL RS22815
gene id: 326424:FRAAL_RS22815
uniprot id: Q0RF85
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

326424:FRAAL RS17890
gene id: 326424:FRAAL_RS17890
uniprot id: Q0RIE2
names: Similarity
messages: Belongs to the cytochrome P450 family.

326424:FRAAL RS21685
gene id: 326424:FRAAL_RS21685
uniprot id: Q0RFX9
names: Similarity
messages: Belongs to the TrpC family.

326424:FRAAL RS02685
gene id: 326424:FRAAL_RS02685
uniprot id: Q0RT10
names: Subcellular Location Annotation
messages: Membrane

326424:FRAAL RS25535
gene id: 326424:FRAAL_RS25535
uniprot id: Q0RDH6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm

326424:FRAAL RS21640
gene id: 326424:FRAAL_RS21640
uniprot id: Q0RFY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

326424:FRAAL RS01390
gene id: 326424:FRAAL_RS01390
uniprot id: Q0RTV7
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

326424:FRAAL RS22945
gene id: 326424:FRAAL_RS22945
uniprot id: Q0RF57
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Monomer.

326424:FRAAL RS08355
gene id: 326424:FRAAL_RS08355
uniprot id: Q0RPF6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

326424:FRAAL RS17080
gene id: 326424:FRAAL_RS17080
uniprot id: Q0RIX0
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

326424:FRAAL RS04485
gene id: 326424:FRAAL_RS04485
uniprot id: Q0RRW0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

326424:FRAAL RS08105
gene id: 326424:FRAAL_RS08105
uniprot id: Q0RPK5
names: Subcellular Location Annotation
messages: Membrane

326424:FRAAL RS22820
gene id: 326424:FRAAL_RS22820
uniprot id: Q0RF84
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

326424:FRAAL RS06190
gene id: 326424:FRAAL_RS06190
uniprot id: Q0RQU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

326424:FRAAL RS27365
gene id: 326424:FRAAL_RS27365
uniprot id: Q0RCD2
names: Similarity
messages: Belongs to the asp23 family.

326424:FRAAL RS14845
gene id: 326424:FRAAL_RS14845
uniprot id: Q0RKB3
names: Similarity
messages: Belongs to the bacterial ring-hydroxylating dioxygenase beta subunit family.

326424:FRAAL RS01750
gene id: 326424:FRAAL_RS01750
uniprot id: Q0RTN3
names: Subcellular Location Annotation
messages: Membrane

326424:FRAAL RS25430
gene id: 326424:FRAAL_RS25430
uniprot id: Q0RDJ9
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

326424:FRAAL RS10355
gene id: 326424:FRAAL_RS10355
uniprot id: Q0RN78
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

326424:FRAAL RS09210
gene id: 326424:FRAAL_RS09210
uniprot id: Q0RNX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 13 family.
messages: Cytoplasm

326424:FRAAL RS21115
gene id: 326424:FRAAL_RS21115
uniprot id: Q0RGB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

326424:FRAAL RS22390
gene id: 326424:FRAAL_RS22390
uniprot id: Q0RFH0
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

326424:FRAAL RS21005
gene id: 326424:FRAAL_RS21005
uniprot id: Q0RGD3
names: Subcellular Location Annotation
messages: Membrane

326424:FRAAL RS11440
gene id: 326424:FRAAL_RS11440
uniprot id: Q0RMH9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

326424:FRAAL RS19710
gene id: 326424:FRAAL_RS19710
uniprot id: Q0RH82
names: Similarity
messages: Belongs to the SAM hydrolase / SAM-dependent halogenase family.

326424:FRAAL RS23180
gene id: 326424:FRAAL_RS23180
uniprot id: Q0RF02
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

326424:FRAAL RS20135
gene id: 326424:FRAAL_RS20135
uniprot id: Q0RGY7
names: Similarity
messages: Belongs to the CdaR family.

326424:FRAAL RS12560
gene id: 326424:FRAAL_RS12560
uniprot id: Q0RLT1
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

326424:FRAAL RS29115
gene id: 326424:FRAAL_RS29115
uniprot id: Q0RB93
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

326424:FRAAL RS19635
gene id: 326424:FRAAL_RS19635
uniprot id: Q0RH98
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

326424:FRAAL RS20845
gene id: 326424:FRAAL_RS20845
uniprot id: Q0RGG7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

326424:FRAAL RS08580
gene id: 326424:FRAAL_RS08580
uniprot id: Q0RPA4
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

326424:FRAAL RS25590
gene id: 326424:FRAAL_RS25590
uniprot id: Q0RDG7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Heterodimer of an alpha and a beta subunit.
messages: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

326424:FRAAL RS15980
gene id: 326424:FRAAL_RS15980
uniprot id: Q0RJL1
names: Subcellular Location Annotation
messages: Membrane

326424:FRAAL RS16825
gene id: 326424:FRAAL_RS16825
uniprot id: Q0RJ24
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

326424:FRAAL RS03950
gene id: 326424:FRAAL_RS03950
uniprot id: Q0RS75
names: Similarity
messages: Belongs to the pirin family.

326424:FRAAL RS14570
gene id: 326424:FRAAL_RS14570
uniprot id: Q0RKH4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Aliphatic sulfonates importer (TC 3.A.1.17.2) family.
messages: Cell membrane
messages: Part of the ABC transporter complex SsuABC involved in aliphatic sulfonates import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (SsuB), two transmembrane proteins (SsuC) and a solute-binding protein (SsuA).

326424:FRAAL RS13100
gene id: 326424:FRAAL_RS13100
uniprot id: Q0RLG0
names: Similarity
messages: Belongs to the flavin oxidoreductase frp family.

326424:FRAAL RS24930
gene id: 326424:FRAAL_RS24930
uniprot id: Q0RDW1
names: Similarity
messages: Belongs to the FPG family.

326424:FRAAL RS14920
gene id: 326424:FRAAL_RS14920
uniprot id: Q0RK95
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

326424:FRAAL RS23035
gene id: 326424:FRAAL_RS23035
uniprot id: Q0RF35
names: Similarity
messages: Belongs to the extradiol ring-cleavage dioxygenase family.

326424:FRAAL RS28365
gene id: 326424:FRAAL_RS28365
uniprot id: Q0RBQ7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IPP isomerase type 1 family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium ion binds only when substrate is bound.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).
messages: Cytoplasm

326424:FRAAL RS04835
gene id: 326424:FRAAL_RS04835
uniprot id: Q0RRP2
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

326424:FRAAL RS25915
gene id: 326424:FRAAL_RS25915
uniprot id: Q0RD95
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

326424:FRAAL RS30020
gene id: 326424:FRAAL_RS30020
uniprot id: Q0RAP5
names: Similarity
messages: Belongs to the thioredoxin family.

326424:FRAAL RS28475
gene id: 326424:FRAAL_RS28475
uniprot id: Q0RBN2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DisA family.
messages: Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation; upon encountering a lesion, the DisA focus arrests at the damaged site and halts c-di-AMP synthesis.
messages: Homooctamer.
messages: Participates in a DNA-damage check-point that is active prior to asymmetric division when DNA is damaged. DisA forms globular foci that rapidly scan along the chromosomes during sporulation, searching for lesions. When a lesion is present, DisA pauses at the lesion site. This triggers a cellular response that culminates in a temporary block in sporulation initiation.

326424:FRAAL RS15420
gene id: 326424:FRAAL_RS15420
uniprot id: Q0RJY8
names: Subcellular Location Annotation
messages: Membrane

326424:FRAAL RS12905
gene id: 326424:FRAAL_RS12905
uniprot id: Q0RLK2
names: Similarity
messages: Belongs to the HIBADH-related family.

326424:FRAAL RS19810
gene id: 326424:FRAAL_RS19810
uniprot id: Q0RH61
names: Similarity
messages: Belongs to the Rv1128c/1148c/1588c/1702c/1945/3466 family.

326424:FRAAL RS00525
gene id: 326424:FRAAL_RS00525
uniprot id: Q0RUF0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

326424:FRAAL RS14740
gene id: 326424:FRAAL_RS14740
uniprot id: Q0RKD7
names: Similarity
messages: Belongs to the cytochrome P450 family.

326424:FRAAL RS25815
gene id: 326424:FRAAL_RS25815
uniprot id: Q0RDB6
names: Function
names: Similarity
messages: Belongs to the PemK/MazF family.
messages: Toxic component of a type II toxin-antitoxin (TA) system.

326424:FRAAL RS04355
gene id: 326424:FRAAL_RS04355
uniprot id: Q0RRY7
names: Function
names: Similarity
messages: Belongs to the MqnA/MqnD family. MqnA subfamily.
messages: Catalyzes the dehydration of chorismate into 3-[(1-carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).

326424:FRAAL RS25595
gene id: 326424:FRAAL_RS25595
uniprot id: Q0RDG6
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta subunit.
messages: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

326424:FRAAL RS20075
gene id: 326424:FRAAL_RS20075
uniprot id: Q0RH01
names: Function
names: Similarity
messages: Belongs to the RapZ-like family.
messages: Displays ATPase and GTPase activities.

326424:FRAAL RS29405
gene id: 326424:FRAAL_RS29405
uniprot id: Q0RB30
names: Function
names: Similarity
messages: Belongs to the MqnA/MqnD family. MqnD subfamily.
messages: Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).

326424:FRAAL RS14155
gene id: 326424:FRAAL_RS14155
uniprot id: Q0RKS5
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

326424:FRAAL RS00240
gene id: 326424:FRAAL_RS00240
uniprot id: Q0RUL1
names: Similarity
messages: Belongs to the peptidase C40 family.

326424:FRAAL RS09330
gene id: 326424:FRAAL_RS09330
uniprot id: Q0RNU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

326424:FRAAL RS08590
gene id: 326424:FRAAL_RS08590
uniprot id: Q0RPA1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

326424:FRAAL RS09790
gene id: 326424:FRAAL_RS09790
uniprot id: Q0RNJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

326424:FRAAL RS24935
gene id: 326424:FRAAL_RS24935
uniprot id: Q0RDW0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

326424:FRAAL RS24970
gene id: 326424:FRAAL_RS24970
uniprot id: Q0RDV0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
messages: Cytoplasm

326424:FRAAL RS15875
gene id: 326424:FRAAL_RS15875
uniprot id: Q0RJN7
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

326424:FRAAL RS16095
gene id: 326424:FRAAL_RS16095
uniprot id: Q0RJI6
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

326424:FRAAL RS25620
gene id: 326424:FRAAL_RS25620
uniprot id: Q0RDG0
names: Function
names: Similarity
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

326424:FRAAL RS26270
gene id: 326424:FRAAL_RS26270
uniprot id: Q0RD21
names: Similarity
messages: Belongs to the peptidase S16 family.

326424:FRAAL RS21325
gene id: 326424:FRAAL_RS21325
uniprot id: Q0RG59
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Catalyzes the reversible hydration of carbon dioxide to form bicarbonate.

326424:FRAAL RS14735
gene id: 326424:FRAAL_RS14735
uniprot id: Q0RKD8
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

326424:FRAAL RS21090
gene id: 326424:FRAAL_RS21090
uniprot id: Q0RGB5
names: Similarity
messages: Belongs to the NtaA/SnaA/DszA monooxygenase family.

326424:FRAAL RS00605
gene id: 326424:FRAAL_RS00605
uniprot id: Q0RUD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

326424:FRAAL RS29070
gene id: 326424:FRAAL_RS29070
uniprot id: Q0RBA3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

326424:FRAAL RS25285
gene id: 326424:FRAAL_RS25285
uniprot id: Q0RDN2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

326424:FRAAL RS12630
gene id: 326424:FRAAL_RS12630
uniprot id: Q0RLR6
names: Similarity
messages: Belongs to the cytochrome P450 family.

326424:FRAAL RS23120
gene id: 326424:FRAAL_RS23120
uniprot id: Q0RF16
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpA family.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds the extracellular potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

326424:FRAAL RS05960
gene id: 326424:FRAAL_RS05960
uniprot id: Q0RR02
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division.

326424:FRAAL RS20080
gene id: 326424:FRAAL_RS20080
uniprot id: Q0RH00
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

326424:FRAAL RS00565
gene id: 326424:FRAAL_RS00565
uniprot id: Q0RUE1
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

326424:FRAAL RS18430
gene id: 326424:FRAAL_RS18430
uniprot id: Q0RI14
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

326424:FRAAL RS27325
gene id: 326424:FRAAL_RS27325
uniprot id: Q0RCE1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

326424:FRAAL RS09435
gene id: 326424:FRAAL_RS09435
uniprot id: Q0RNS6
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

326424:FRAAL RS28995
gene id: 326424:FRAAL_RS28995
uniprot id: Q0RBC0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

326424:FRAAL RS25840
gene id: 326424:FRAAL_RS25840
uniprot id: Q0RDB1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

326424:FRAAL RS13355
gene id: 326424:FRAAL_RS13355
uniprot id: Q0RLA7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

326424:FRAAL RS14040
gene id: 326424:FRAAL_RS14040
uniprot id: Q0RKU9
names: Similarity
messages: Belongs to the cytochrome P450 family.

326424:FRAAL RS27550
gene id: 326424:FRAAL_RS27550
uniprot id: Q0RC92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane

326424:FRAAL RS11180
gene id: 326424:FRAAL_RS11180
uniprot id: Q0RMP2
names: Similarity
messages: Belongs to the cytochrome P450 family.

326424:FRAAL RS28690
gene id: 326424:FRAAL_RS28690
uniprot id: Q0RBI8
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

326424:FRAAL RS26780
gene id: 326424:FRAAL_RS26780
uniprot id: Q0RCR0
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

326424:FRAAL RS29965
gene id: 326424:FRAAL_RS29965
uniprot id: Q0RAQ7
names: Similarity
messages: Belongs to the myo-inositol 1-phosphate synthase family.

326424:FRAAL RS07950
gene id: 326424:FRAAL_RS07950
uniprot id: Q0RPN7
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

326424:FRAAL RS00815
gene id: 326424:FRAAL_RS00815
uniprot id: Q0RU88
names: Subcellular Location Annotation
messages: Membrane

326424:FRAAL RS29485
gene id: 326424:FRAAL_RS29485
uniprot id: Q0RB13
names: Subcellular Location Annotation
messages: Membrane

326424:FRAAL RS28120
gene id: 326424:FRAAL_RS28120
uniprot id: Q0RBW3
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

326424:FRAAL RS19470
gene id: 326424:FRAAL_RS19470
uniprot id: Q0RHD6
names: Similarity
messages: Belongs to the NtaA/SnaA/DszA monooxygenase family.

326424:FRAAL RS02915
gene id: 326424:FRAAL_RS02915
uniprot id: Q0RSW2
names: Caution
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

326424:FRAAL RS25825
gene id: 326424:FRAAL_RS25825
uniprot id: Q0RDB4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

326424:FRAAL RS21985
gene id: 326424:FRAAL_RS21985
uniprot id: Q0RFQ7
names: Similarity
messages: Belongs to the ice-binding protein family.

326424:FRAAL RS05045
gene id: 326424:FRAAL_RS05045
uniprot id: Q0RRJ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

326424:FRAAL RS07725
gene id: 326424:FRAAL_RS07725
uniprot id: Q0RPT5
names: Similarity
messages: Belongs to the glycosyl hydrolase 26 family.

326424:FRAAL RS15290
gene id: 326424:FRAAL_RS15290
uniprot id: Q0RK14
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

326424:FRAAL RS25760
gene id: 326424:FRAAL_RS25760
uniprot id: Q0RDC8
names: Subcellular Location Annotation
messages: Membrane

326424:FRAAL RS28660
gene id: 326424:FRAAL_RS28660
uniprot id: Q0RBJ4
names: Subcellular Location Annotation
messages: Membrane

326424:FRAAL RS02400
gene id: 326424:FRAAL_RS02400
uniprot id: Q0RT74
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

326424:FRAAL RS28025
gene id: 326424:FRAAL_RS28025
uniprot id: Q0RBY5
names: Similarity
messages: Belongs to the group II decarboxylase family.

326424:FRAAL RS26980
gene id: 326424:FRAAL_RS26980
uniprot id: Q0RCL6
names: Similarity
messages: Belongs to the NtaA/SnaA/DszA monooxygenase family.

326424:FRAAL RS05265
gene id: 326424:FRAAL_RS05265
uniprot id: Q0RRF1
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

326424:FRAAL RS08395
gene id: 326424:FRAAL_RS08395
uniprot id: Q0RPE8
names: Similarity
messages: Belongs to the phosphohexose mutase family.

326424:FRAAL RS07855
gene id: 326424:FRAAL_RS07855
uniprot id: Q0RPQ7
names: Similarity
messages: Belongs to the HypD family.

326424:FRAAL RS21195
gene id: 326424:FRAAL_RS21195
uniprot id: Q0RG91
names: Subcellular Location Annotation
messages: Membrane

326424:FRAAL RS26775
gene id: 326424:FRAAL_RS26775
uniprot id: Q0RCR2
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

326424:FRAAL RS10960
gene id: 326424:FRAAL_RS10960
uniprot id: Q0RMU4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

326424:FRAAL RS00945
gene id: 326424:FRAAL_RS00945
uniprot id: Q0RU60
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

326424:FRAAL RS04625
gene id: 326424:FRAAL_RS04625
uniprot id: Q0RRT6
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

326424:FRAAL RS29805
gene id: 326424:FRAAL_RS29805
uniprot id: Q0RAU1
names: Similarity
messages: Belongs to the DyP-type peroxidase family.

326424:FRAAL RS29640
gene id: 326424:FRAAL_RS29640
uniprot id: Q0RAX7
names: Subcellular Location Annotation
messages: Cytoplasm

326424:FRAAL RS16065
gene id: 326424:FRAAL_RS16065
uniprot id: Q0RJJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

326424:FRAAL RS10950
gene id: 326424:FRAAL_RS10950
uniprot id: Q0RMU6
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

326424:FRAAL RS02790
gene id: 326424:FRAAL_RS02790
uniprot id: Q0RSZ2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MurCDEF family. MurT subfamily.
messages: Forms a heterodimer with GatD.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The MurT subunit catalyzes the ATP-dependent amidation of D-glutamate residue of lipid II, converting it to an isoglutamine residue.

326424:FRAAL RS04880
gene id: 326424:FRAAL_RS04880
uniprot id: Q0RRN3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

326424:FRAAL RS06570
gene id: 326424:FRAAL_RS06570
uniprot id: Q0RQK9
names: Similarity
messages: Belongs to the HIBADH-related family.

326424:FRAAL RS17655
gene id: 326424:FRAAL_RS17655
uniprot id: Q0RIJ5
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

326424:FRAAL RS04670
gene id: 326424:FRAAL_RS04670
uniprot id: Q0RRS5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

326424:FRAAL RS21895
gene id: 326424:FRAAL_RS21895
uniprot id: Q0RFS9
names: Function
names: Similarity
messages: Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.
messages: Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate.

326424:FRAAL RS16540
gene id: 326424:FRAAL_RS16540
uniprot id: Q0RJ88
names: Subcellular Location Annotation
messages: Membrane

326424:FRAAL RS17395
gene id: 326424:FRAAL_RS17395
uniprot id: Q0RIQ4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

326424:FRAAL RS13740
gene id: 326424:FRAAL_RS13740
uniprot id: Q0RL16
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

326424:FRAAL RS04645
gene id: 326424:FRAAL_RS04645
uniprot id: Q0RRT0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

326424:FRAAL RS10440
gene id: 326424:FRAAL_RS10440
uniprot id: Q0RN55
names: Function
names: Similarity
messages: Belongs to the HypA/HybF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.

326424:FRAAL RS16485
gene id: 326424:FRAAL_RS16485
uniprot id: Q0RJA0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

326424:FRAAL RS23595
gene id: 326424:FRAAL_RS23595
uniprot id: Q0RER1
names: Subcellular Location Annotation
messages: Membrane

326424:FRAAL RS14415
gene id: 326424:FRAAL_RS14415
uniprot id: Q0RKL5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

326424:FRAAL RS09980
gene id: 326424:FRAAL_RS09980
uniprot id: Q0RNF3
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

326424:FRAAL RS10620
gene id: 326424:FRAAL_RS10620
uniprot id: Q0RN11
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
messages: Belongs to the azoreductase type 1 family.
messages: Binds 1 FMN per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones.

326424:FRAAL RS15340
gene id: 326424:FRAAL_RS15340
uniprot id: Q0RK04
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

326424:FRAAL RS23500
gene id: 326424:FRAAL_RS23500
uniprot id: Q0RET4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

326424:FRAAL RS13010
gene id: 326424:FRAAL_RS13010
uniprot id: Q0RLI0
names: Subcellular Location Annotation
messages: Membrane

326424:FRAAL RS07270
gene id: 326424:FRAAL_RS07270
uniprot id: Q0RQ43
names: Subcellular Location Annotation
messages: Membrane

326424:FRAAL RS25475
gene id: 326424:FRAAL_RS25475
uniprot id: Q0RDI9
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

326424:FRAAL RS18340
gene id: 326424:FRAAL_RS18340
uniprot id: Q0RI34
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

326424:FRAAL RS14110
gene id: 326424:FRAAL_RS14110
uniprot id: Q0RKT5
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

326424:FRAAL RS00335
gene id: 326424:FRAAL_RS00335
uniprot id: Q0RUI8
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

326424:FRAAL RS31395
gene id: 326424:FRAAL_RS31395
uniprot id: Q0RQE7
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

326424:FRAAL RS21120
gene id: 326424:FRAAL_RS21120
uniprot id: Q0RGA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

326424:FRAAL RS18690
gene id: 326424:FRAAL_RS18690
uniprot id: Q0RHV6
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

326424:FRAAL RS05020
gene id: 326424:FRAAL_RS05020
uniprot id: Q0RRK4
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

326424:FRAAL RS02605
gene id: 326424:FRAAL_RS02605
uniprot id: Q0RT26
names: Subcellular Location Annotation
messages: Cytoplasm

326424:FRAAL RS25540
gene id: 326424:FRAAL_RS25540
uniprot id: Q0RDH5
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.

326424:FRAAL RS18850
gene id: 326424:FRAAL_RS18850
uniprot id: Q0RHR7
names: Subcellular Location Annotation
messages: Cell membrane

326424:FRAAL RS24640
gene id: 326424:FRAAL_RS24640
uniprot id: Q0RE21
names: Similarity
messages: Belongs to the polysaccharide synthase family.

326424:FRAAL RS01495
gene id: 326424:FRAAL_RS01495
uniprot id: Q0RTT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

326424:FRAAL RS08750
gene id: 326424:FRAAL_RS08750
uniprot id: Q0RP67
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

326424:FRAAL RS04815
gene id: 326424:FRAAL_RS04815
uniprot id: Q0RRP6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

326424:FRAAL RS04950
gene id: 326424:FRAAL_RS04950
uniprot id: Q0RRL8
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

326424:FRAAL RS30945
gene id: 326424:FRAAL_RS30945
uniprot id: Q0RPT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

326424:FRAAL RS06085
gene id: 326424:FRAAL_RS06085
uniprot id: Q0RQW9
names: Similarity
messages: Belongs to the bacterial lectin family.

326424:FRAAL RS12285
gene id: 326424:FRAAL_RS12285
uniprot id: Q0RLY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

326424:FRAAL RS29260
gene id: 326424:FRAAL_RS29260
uniprot id: Q0RB64
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

326424:FRAAL RS26555
gene id: 326424:FRAAL_RS26555
uniprot id: Q0RCW2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatB family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

326424:FRAAL RS09175
gene id: 326424:FRAAL_RS09175
uniprot id: Q0RNX9
names: Similarity
messages: Belongs to the PAPS reductase family. CysD subfamily.

326424:FRAAL RS25875
gene id: 326424:FRAAL_RS25875
uniprot id: Q0RDA3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

326424:FRAAL RS09040
gene id: 326424:FRAAL_RS09040
uniprot id: Q0RP06
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

326424:FRAAL RS23495
gene id: 326424:FRAAL_RS23495
uniprot id: Q0RET5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

326424:FRAAL RS00355
gene id: 326424:FRAAL_RS00355
uniprot id: Q0RUI4
names: Similarity
messages: Belongs to the CapA family.

326424:FRAAL RS16360
gene id: 326424:FRAAL_RS16360
uniprot id: Q0RJC9
names: Similarity
messages: Belongs to the peptidase S33 family.

326424:FRAAL RS04590
gene id: 326424:FRAAL_RS04590
uniprot id: Q0RRU1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

326424:FRAAL RS22745
gene id: 326424:FRAAL_RS22745
uniprot id: Q0RF99
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

326424:FRAAL RS25180
gene id: 326424:FRAAL_RS25180
uniprot id: Q0RDQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

326424:FRAAL RS01770
gene id: 326424:FRAAL_RS01770
uniprot id: Q0RTM7
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

326424:FRAAL RS06050
gene id: 326424:FRAAL_RS06050
uniprot id: Q0RQX7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

326424:FRAAL RS33930
gene id: 326424:FRAAL_RS33930
uniprot id: Q0RTP3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

326424:FRAAL RS05525
gene id: 326424:FRAAL_RS05525
uniprot id: Q0RR96
names: Function
names: Similarity
messages: Catalyzes the radical-mediated synthesis of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (FO) from 5-amino-6-(D-ribitylamino)uracil and L-tyrosine.
messages: In the C-terminal section; belongs to the radical SAM superfamily. CofH family.
messages: In the N-terminal section; belongs to the radical SAM superfamily. CofG family.

326424:FRAAL RS18755
gene id: 326424:FRAAL_RS18755
uniprot id: Q0RHU1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sirtuin family. Class II subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form.

326424:FRAAL RS09515
gene id: 326424:FRAAL_RS09515
uniprot id: Q0RNQ8
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

326424:FRAAL RS15060
gene id: 326424:FRAAL_RS15060
uniprot id: Q0RK64
names: Similarity
messages: Belongs to the CFA/CMAS family.

326424:FRAAL RS09140
gene id: 326424:FRAAL_RS09140
uniprot id: Q0RNY6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

326424:FRAAL RS19950
gene id: 326424:FRAAL_RS19950
uniprot id: Q0RH29
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

326424:FRAAL RS15900
gene id: 326424:FRAAL_RS15900
uniprot id: Q0RJN2
names: Similarity
messages: Belongs to the Nudix hydrolase family.

326424:FRAAL RS21550
gene id: 326424:FRAAL_RS21550
uniprot id: Q0RG08
names: Subcellular Location Annotation
messages: Membrane

326424:FRAAL RS14905
gene id: 326424:FRAAL_RS14905
uniprot id: Q0RK98
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

326424:FRAAL RS17405
gene id: 326424:FRAAL_RS17405
uniprot id: Q0RIQ2
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

326424:FRAAL RS17305
gene id: 326424:FRAAL_RS17305
uniprot id: Q0RIS4
names: Function
names: Similarity
messages: Belongs to the ApbE family.
messages: Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.

326424:FRAAL RS05355
gene id: 326424:FRAAL_RS05355
uniprot id: Q0RRD2
names: Subcellular Location Annotation
messages: Membrane

326424:FRAAL RS04270
gene id: 326424:FRAAL_RS04270
uniprot id: Q0RS04
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

326424:FRAAL RS07220
gene id: 326424:FRAAL_RS07220
uniprot id: Q0RQ53
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

326424:FRAAL RS08280
gene id: 326424:FRAAL_RS08280
uniprot id: Q0RPH0
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

326424:FRAAL RS19285
gene id: 326424:FRAAL_RS19285
uniprot id: Q0RHH6
names: Similarity
messages: Belongs to the CFA/CMAS family.

326424:FRAAL RS25305
gene id: 326424:FRAAL_RS25305
uniprot id: Q0RDM7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

326424:FRAAL RS19305
gene id: 326424:FRAAL_RS19305
uniprot id: Q0RHH1
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

326424:FRAAL RS15585
gene id: 326424:FRAAL_RS15585
uniprot id: Q0RJV3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

326424:FRAAL RS00175
gene id: 326424:FRAAL_RS00175
uniprot id: Q0RUM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Membrane

326424:FRAAL RS28470
gene id: 326424:FRAAL_RS28470
uniprot id: Q0RBN3
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

326424:FRAAL RS14075
gene id: 326424:FRAAL_RS14075
uniprot id: Q0RKU2
names: Subcellular Location Annotation
messages: Membrane

326424:FRAAL RS08700
gene id: 326424:FRAAL_RS08700
uniprot id: Q0RP78
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

326424:FRAAL RS22600
gene id: 326424:FRAAL_RS22600
uniprot id: Q0RFC4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

326424:FRAAL RS21595
gene id: 326424:FRAAL_RS21595
uniprot id: Q0RFZ7
names: Subunit
messages: Heterodimer of an alpha and a beta chain.

326424:FRAAL RS10660
gene id: 326424:FRAAL_RS10660
uniprot id: Q0RN02
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

326424:FRAAL RS26750
gene id: 326424:FRAAL_RS26750
uniprot id: Q0RCR8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

326424:FRAAL RS04510
gene id: 326424:FRAAL_RS04510
uniprot id: Q0RRV5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

326424:FRAAL RS21260
gene id: 326424:FRAAL_RS21260
uniprot id: Q0RG75
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

326424:FRAAL RS24985
gene id: 326424:FRAAL_RS24985
uniprot id: Q0RDU7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

326424:FRAAL RS25320
gene id: 326424:FRAAL_RS25320
uniprot id: Q0RDM2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

326424:FRAAL RS10210
gene id: 326424:FRAAL_RS10210
uniprot id: Q0RNA7
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

326424:FRAAL RS16300
gene id: 326424:FRAAL_RS16300
uniprot id: Q0RJE2
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family.

326424:FRAAL RS25885
gene id: 326424:FRAAL_RS25885
uniprot id: Q0RDA1
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

326424:FRAAL RS26390
gene id: 326424:FRAAL_RS26390
uniprot id: Q0RCZ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic Ku family.
messages: Homodimer. Interacts with LigD.
messages: With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD.

326424:FRAAL RS22890
gene id: 326424:FRAAL_RS22890
uniprot id: Q0RF70
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

326424:FRAAL RS14935
gene id: 326424:FRAAL_RS14935
uniprot id: Q0RK92
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

326424:FRAAL RS17635
gene id: 326424:FRAAL_RS17635
uniprot id: Q0RIK1
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

326424:FRAAL RS13585
gene id: 326424:FRAAL_RS13585
uniprot id: Q0RL52
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

326424:FRAAL RS17450
gene id: 326424:FRAAL_RS17450
uniprot id: Q0RIP3
names: Similarity
messages: Belongs to the UPF0098 family.

326424:FRAAL RS01680
gene id: 326424:FRAAL_RS01680
uniprot id: Q0RTP7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

326424:FRAAL RS09585
gene id: 326424:FRAAL_RS09585
uniprot id: Q0RNP4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane

326424:FRAAL RS24815
gene id: 326424:FRAAL_RS24815
uniprot id: Q0RDY5
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

326424:FRAAL RS04900
gene id: 326424:FRAAL_RS04900
uniprot id: Q0RRM8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

326424:FRAAL RS21015
gene id: 326424:FRAAL_RS21015
uniprot id: Q0RGD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

326424:FRAAL RS12510
gene id: 326424:FRAAL_RS12510
uniprot id: Q0RLU1
names: Domain
names: Function
names: Similarity
names: Subunit
messages: ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis.
messages: Belongs to the AAA ATPase family.
messages: Consists of three main regions, an N-terminal coiled-coil domain that binds to protein Pup and functions as a docking station, an interdomain involved in ARC hexamerization, and a C-terminal ATPase domain of the AAA type.
messages: Homohexamer. Assembles into a hexameric ring structure that caps the 20S proteasome core. Strongly interacts with the prokaryotic ubiquitin-like protein Pup through a hydrophobic interface; the interacting region of ARC lies in its N-terminal coiled-coil domain. There is one Pup binding site per ARC hexamer ring. Upon ATP-binding, the C-terminus of ARC interacts with the alpha-rings of the proteasome core, possibly by binding to the intersubunit pockets.

326424:FRAAL RS22515
gene id: 326424:FRAAL_RS22515
uniprot id: Q0RFE2
names: Similarity
messages: Belongs to the glutamine synthetase family.

326424:FRAAL RS18545
gene id: 326424:FRAAL_RS18545
uniprot id: Q0RHY8
names: Similarity
messages: Belongs to the universal stress protein A family.

326424:FRAAL RS22325
gene id: 326424:FRAAL_RS22325
uniprot id: Q0RFI3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.

326424:FRAAL RS20930
gene id: 326424:FRAAL_RS20930
uniprot id: Q0RGF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

326424:FRAAL RS25290
gene id: 326424:FRAAL_RS25290
uniprot id: Q0RDN0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

326424:FRAAL RS00125
gene id: 326424:FRAAL_RS00125
uniprot id: Q0RUN7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

326424:FRAAL RS19895
gene id: 326424:FRAAL_RS19895
uniprot id: Q0RH42
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

326424:FRAAL RS27420
gene id: 326424:FRAAL_RS27420
uniprot id: Q0RCC0
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

326424:FRAAL RS10375
gene id: 326424:FRAAL_RS10375
uniprot id: Q0RN74
names: Subcellular Location Annotation
messages: Membrane

326424:FRAAL RS02415
gene id: 326424:FRAAL_RS02415
uniprot id: Q0RT71
names: Similarity
messages: Belongs to the peptidase S33 family.

326424:FRAAL RS22120
gene id: 326424:FRAAL_RS22120
uniprot id: Q0RFM8
names: Subcellular Location Annotation
messages: Membrane

326424:FRAAL RS06910
gene id: 326424:FRAAL_RS06910
uniprot id: Q0RQC5
names: Similarity
messages: Belongs to the SCO1/2 family.

326424:FRAAL RS30045
gene id: 326424:FRAAL_RS30045
uniprot id: Q0RAP0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Specifically methylates the N7 position of guanine in position 518 of 16S rRNA.

326424:FRAAL RS19345
gene id: 326424:FRAAL_RS19345
uniprot id: Q0RHG1
names: Subcellular Location Annotation
messages: Membrane

326424:FRAAL RS20005
gene id: 326424:FRAAL_RS20005
uniprot id: Q0RH18
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 2 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

326424:FRAAL RS05620
gene id: 326424:FRAAL_RS05620
uniprot id: Q0RR76
names: Subcellular Location Annotation
messages: Membrane

326424:FRAAL RS04205
gene id: 326424:FRAAL_RS04205
uniprot id: Q0RS20
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

326424:FRAAL RS16255
gene id: 326424:FRAAL_RS16255
uniprot id: Q0RJF1
names: Function
names: Similarity
messages: Belongs to the UPF0677 family.
messages: Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity.

326424:FRAAL RS18615
gene id: 326424:FRAAL_RS18615
uniprot id: Q0RHX4
names: Similarity
messages: Belongs to the creatininase superfamily.

326424:FRAAL RS13105
gene id: 326424:FRAAL_RS13105
uniprot id: Q0RLF8
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

326424:FRAAL RS09335
gene id: 326424:FRAAL_RS09335
uniprot id: Q0RNU8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RuvC family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.

326424:FRAAL RS04800
gene id: 326424:FRAAL_RS04800
uniprot id: Q0RRP9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

326424:FRAAL RS09355
gene id: 326424:FRAAL_RS09355
uniprot id: Q0RNU3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

326424:FRAAL RS01900
gene id: 326424:FRAAL_RS01900
uniprot id: Q0RTK0
names: Subcellular Location Annotation
messages: Membrane

326424:FRAAL RS28805
gene id: 326424:FRAAL_RS28805
uniprot id: Q0RBG4
names: Similarity
names: Subunit
messages: Belongs to the Bpa family.
messages: Forms a homooligomeric, either hexameric or heptameric, ring-like structure which stacks co-axially with the proteasomal alpha-rings.

326424:FRAAL RS24385
gene id: 326424:FRAAL_RS24385
uniprot id: Q0RE77
names: Subcellular Location Annotation
messages: Membrane

326424:FRAAL RS24315
gene id: 326424:FRAAL_RS24315
uniprot id: Q0RE95
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

326424:FRAAL RS26130
gene id: 326424:FRAAL_RS26130
uniprot id: Q0RD51
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

326424:FRAAL RS03375
gene id: 326424:FRAAL_RS03375
uniprot id: Q0RSL0
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

326424:FRAAL RS06200
gene id: 326424:FRAAL_RS06200
uniprot id: Q0RQU2
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

326424:FRAAL RS24300
gene id: 326424:FRAAL_RS24300
uniprot id: Q0RE98
names: Function
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).

326424:FRAAL RS28215
gene id: 326424:FRAAL_RS28215
uniprot id: Q0RBU0
names: Subcellular Location Annotation
messages: Membrane

326424:FRAAL RS12535
gene id: 326424:FRAAL_RS12535
uniprot id: Q0RLT6
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
messages: Cytoplasm
messages: The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped by the proteasome-associated ATPase, ARC.
messages: The formation of the proteasomal ATPase ARC-20S proteasome complex, likely via the docking of the C-termini of ARC into the intersubunit pockets in the alpha-rings, may trigger opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity.

326424:FRAAL RS08525
gene id: 326424:FRAAL_RS08525
uniprot id: Q0RPB6
names: Similarity
messages: Belongs to the metallo-beta-lactamase superfamily. Class-B beta-lactamase family.

326424:FRAAL RS25045
gene id: 326424:FRAAL_RS25045
uniprot id: Q0RDT4
names: Similarity
messages: Belongs to the heat shock protein 70 family.

326424:FRAAL RS29160
gene id: 326424:FRAAL_RS29160
uniprot id: Q0RB84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

326424:FRAAL RS08450
gene id: 326424:FRAAL_RS08450
uniprot id: Q0RPD4
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

326424:FRAAL RS22520
gene id: 326424:FRAAL_RS22520
uniprot id: Q0RFE1
names: Function
names: Similarity
messages: Belongs to the GlnE family.
messages: Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell.

326424:FRAAL RS25025
gene id: 326424:FRAAL_RS25025
uniprot id: Q0RDT8
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

326424:FRAAL RS26705
gene id: 326424:FRAAL_RS26705
uniprot id: Q0RCS7
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

326424:FRAAL RS06965
gene id: 326424:FRAAL_RS06965
uniprot id: Q0RQA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0014 family.
messages: Membrane

326424:FRAAL RS08290
gene id: 326424:FRAAL_RS08290
uniprot id: Q0RPG8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

326424:FRAAL RS25070
gene id: 326424:FRAAL_RS25070
uniprot id: Q0RDS9
names: Similarity
messages: Belongs to the ribF family.

326424:FRAAL RS25200
gene id: 326424:FRAAL_RS25200
uniprot id: Q0RDQ1
names: Similarity
messages: Belongs to the DprA/Smf family.

326424:FRAAL RS13215
gene id: 326424:FRAAL_RS13215
uniprot id: Q0RLD6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gas vesicle protein type A family.
messages: Gas vesicles are small, hollow, gas filled protein structures that are found in several microbial planktonic microorganisms. They allow the positioning of the organism at the favorable depth for growth. GvpA type proteins form the essential core of the structure.
messages: gas vesicle membrane

326424:FRAAL RS04725
gene id: 326424:FRAAL_RS04725
uniprot id: Q0RRR4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

326424:FRAAL RS20790
gene id: 326424:FRAAL_RS20790
uniprot id: Q0RGH9
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

326424:FRAAL RS13300
gene id: 326424:FRAAL_RS13300
uniprot id: Q0RLB8
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

326424:FRAAL RS22885
gene id: 326424:FRAAL_RS22885
uniprot id: Q0RF71
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Monomer.

326424:FRAAL RS22670
gene id: 326424:FRAAL_RS22670
uniprot id: Q0RFB4
names: Similarity
messages: Belongs to the DNA glycosylase MPG family.

326424:FRAAL RS14760
gene id: 326424:FRAAL_RS14760
uniprot id: Q0RKD3
names: Similarity
messages: Belongs to the Rv1128c/1148c/1588c/1702c/1945/3466 family.

326424:FRAAL RS08705
gene id: 326424:FRAAL_RS08705
uniprot id: Q0RP77
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

326424:FRAAL RS18550
gene id: 326424:FRAAL_RS18550
uniprot id: Q0RHY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

326424:FRAAL RS26095
gene id: 326424:FRAAL_RS26095
uniprot id: Q0RD59
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.

326424:FRAAL RS12965
gene id: 326424:FRAAL_RS12965
uniprot id: Q0RLJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CbxX/CfxQ family.
messages: Cytoplasm

326424:FRAAL RS16610
gene id: 326424:FRAAL_RS16610
uniprot id: Q0RJ73
names: Subcellular Location Annotation
messages: Membrane

326424:FRAAL RS20800
gene id: 326424:FRAAL_RS20800
uniprot id: Q0RGH7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

326424:FRAAL RS26795
gene id: 326424:FRAAL_RS26795
uniprot id: Q0RCQ7
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

326424:FRAAL RS21545
gene id: 326424:FRAAL_RS21545
uniprot id: Q0RG09
names: Subcellular Location Annotation
messages: Membrane

326424:FRAAL RS06735
gene id: 326424:FRAAL_RS06735
uniprot id: Q0RQG6
names: Similarity
messages: Belongs to the UDP-glycosyltransferase family.

326424:FRAAL RS29005
gene id: 326424:FRAAL_RS29005
uniprot id: Q0RBB8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pseudouridine-5'-phosphate glycosidase family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the reversible cleavage of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway.
messages: Homotrimer.

326424:FRAAL RS25845
gene id: 326424:FRAAL_RS25845
uniprot id: Q0RDB0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.

326424:FRAAL RS22485
gene id: 326424:FRAAL_RS22485
uniprot id: Q0RFE9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

326424:FRAAL RS23425
gene id: 326424:FRAAL_RS23425
uniprot id: Q0REU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SsgA family.
messages: Cell septum

326424:FRAAL RS08760
gene id: 326424:FRAAL_RS08760
uniprot id: Q0RP65
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

326424:FRAAL RS00885
gene id: 326424:FRAAL_RS00885
uniprot id: Q0RU73
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

326424:FRAAL RS18325
gene id: 326424:FRAAL_RS18325
uniprot id: Q0RI37
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

326424:FRAAL RS06690
gene id: 326424:FRAAL_RS06690
uniprot id: Q0RQI0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Heptamer of 7 subunits arranged in a ring.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

326424:FRAAL RS28865
gene id: 326424:FRAAL_RS28865
uniprot id: Q0RBE8
names: Subcellular Location Annotation
messages: Membrane

326424:FRAAL RS25260
gene id: 326424:FRAAL_RS25260
uniprot id: Q0RDN9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

326424:FRAAL RS00520
gene id: 326424:FRAAL_RS00520
uniprot id: Q0RUF1
names: Similarity
messages: Belongs to the citrate synthase family.

326424:FRAAL RS06300
gene id: 326424:FRAAL_RS06300
uniprot id: Q0RQR8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease gamma subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

326424:FRAAL RS09965
gene id: 326424:FRAAL_RS09965
uniprot id: Q0RNF6
names: Similarity
messages: Belongs to the glycosyltransferase 20 family.

326424:FRAAL RS11750
gene id: 326424:FRAAL_RS11750
uniprot id: Q0RMA8
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

326424:FRAAL RS08135
gene id: 326424:FRAAL_RS08135
uniprot id: Q0RPJ8
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

326424:FRAAL RS07780
gene id: 326424:FRAAL_RS07780
uniprot id: Q0RPS4
names: Similarity
messages: Belongs to the carnitine/choline acetyltransferase family.

326424:FRAAL RS22915
gene id: 326424:FRAAL_RS22915
uniprot id: Q0RF65
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

326424:FRAAL RS00510
gene id: 326424:FRAAL_RS00510
uniprot id: Q0RUF3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
messages: Homodimer.

326424:FRAAL RS22840
gene id: 326424:FRAAL_RS22840
uniprot id: Q0RF80
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

326424:FRAAL RS09430
gene id: 326424:FRAAL_RS09430
uniprot id: Q0RNS7
names: Similarity
messages: Belongs to the carotenoid/retinoid oxidoreductase family.

326424:FRAAL RS22675
gene id: 326424:FRAAL_RS22675
uniprot id: Q0RFB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

326424:FRAAL RS14915
gene id: 326424:FRAAL_RS14915
uniprot id: Q0RK96
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

326424:FRAAL RS04220
gene id: 326424:FRAAL_RS04220
uniprot id: Q0RS17
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

326424:FRAAL RS23270
gene id: 326424:FRAAL_RS23270
uniprot id: Q0REY3
names: Similarity
messages: Belongs to the peptidase C56 family.

326424:FRAAL RS21655
gene id: 326424:FRAAL_RS21655
uniprot id: Q0RFY5
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

326424:FRAAL RS25235
gene id: 326424:FRAAL_RS25235
uniprot id: Q0RDP4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

326424:FRAAL RS12215
gene id: 326424:FRAAL_RS12215
uniprot id: Q0RM05
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Catalyzes the reversible hydration of carbon dioxide to form bicarbonate.

326424:FRAAL RS10010
gene id: 326424:FRAAL_RS10010
uniprot id: Q0RNE7
names: Subcellular Location Annotation
messages: Membrane

326424:FRAAL RS18205
gene id: 326424:FRAAL_RS18205
uniprot id: Q0RI66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

326424:FRAAL RS26085
gene id: 326424:FRAAL_RS26085
uniprot id: Q0RD61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

326424:FRAAL RS10650
gene id: 326424:FRAAL_RS10650
uniprot id: Q0RN04
names: Similarity
messages: Belongs to the YoeB family.

326424:FRAAL RS02200
gene id: 326424:FRAAL_RS02200
uniprot id: Q0RTB9
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

326424:FRAAL RS00710
gene id: 326424:FRAAL_RS00710
uniprot id: Q0RUA9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

326424:FRAAL RS13065
gene id: 326424:FRAAL_RS13065
uniprot id: Q0RLG9
names: Subcellular Location Annotation
messages: Cytoplasm

326424:FRAAL RS16070
gene id: 326424:FRAAL_RS16070
uniprot id: Q0RJJ1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane

326424:FRAAL RS08945
gene id: 326424:FRAAL_RS08945
uniprot id: Q0RP27
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

326424:FRAAL RS15655
gene id: 326424:FRAAL_RS15655
uniprot id: Q0RJT4
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

326424:FRAAL RS26960
gene id: 326424:FRAAL_RS26960
uniprot id: Q0RCM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

326424:FRAAL RS06940
gene id: 326424:FRAAL_RS06940
uniprot id: Q0RQB5
names: Similarity
messages: Belongs to the peptidase M1 family.

326424:FRAAL RS02130
gene id: 326424:FRAAL_RS02130
uniprot id: Q0RTD6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

326424:FRAAL RS09640
gene id: 326424:FRAAL_RS09640
uniprot id: Q0RNN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DivIVA family.
messages: Cytoplasm

326424:FRAAL RS10955
gene id: 326424:FRAAL_RS10955
uniprot id: Q0RMU5
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit A family.

326424:FRAAL RS28975
gene id: 326424:FRAAL_RS28975
uniprot id: Q0RBC4
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

326424:FRAAL RS25085
gene id: 326424:FRAAL_RS25085
uniprot id: Q0RDS6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

326424:FRAAL RS04860
gene id: 326424:FRAAL_RS04860
uniprot id: Q0RRN7
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

326424:FRAAL RS29885
gene id: 326424:FRAAL_RS29885
uniprot id: Q0RAS5
names: Function
messages: Catalyzes the hydrolysis of the gamma-glutamyl amide bond of hercynyl-gamma-L-glutamyl-L-cysteine sulfoxide to produce hercynylcysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine.

326424:FRAAL RS05170
gene id: 326424:FRAAL_RS05170
uniprot id: Q0RRH0
names: Cofactor
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.

326424:FRAAL RS09600
gene id: 326424:FRAAL_RS09600
uniprot id: Q0RNP1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).

326424:FRAAL RS25310
gene id: 326424:FRAAL_RS25310
uniprot id: Q0RDM5
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.

326424:FRAAL RS05245
gene id: 326424:FRAAL_RS05245
uniprot id: Q0RRF5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.

326424:FRAAL RS08260
gene id: 326424:FRAAL_RS08260
uniprot id: Q0RPH4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

326424:FRAAL RS21255
gene id: 326424:FRAAL_RS21255
uniprot id: Q0RG76
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

326424:FRAAL RS18140
gene id: 326424:FRAAL_RS18140
uniprot id: Q0RI82
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

326424:FRAAL RS00915
gene id: 326424:FRAAL_RS00915
uniprot id: Q0RU67
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

326424:FRAAL RS26965
gene id: 326424:FRAAL_RS26965
uniprot id: Q0RCL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

326424:FRAAL RS21800
gene id: 326424:FRAAL_RS21800
uniprot id: Q0RFU9
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

326424:FRAAL RS22690
gene id: 326424:FRAAL_RS22690
uniprot id: Q0RFB0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

326424:FRAAL RS29715
gene id: 326424:FRAAL_RS29715
uniprot id: Q0RAW2
uniprot id: Q2TT19
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NifW family.
messages: Homotrimer; associates with NifD.
messages: May protect the nitrogenase Fe-Mo protein from oxidative damage.

326424:FRAAL RS29100
gene id: 326424:FRAAL_RS29100
uniprot id: Q0RB96
names: Similarity
messages: Belongs to the SAICAR synthetase family.

326424:FRAAL RS18405
gene id: 326424:FRAAL_RS18405
uniprot id: Q0RI20
names: Similarity
messages: Belongs to the YciI family.

326424:FRAAL RS01500
gene id: 326424:FRAAL_RS01500
uniprot id: Q0RTT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

326424:FRAAL RS12555
gene id: 326424:FRAAL_RS12555
uniprot id: Q0RLT2
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the Pup ligase/Pup deamidase family. Pup-conjugating enzyme subfamily.
messages: Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine.
messages: The reaction mechanism probably proceeds via the activation of Pup by phosphorylation of its C-terminal glutamate, which is then subject to nucleophilic attack by the substrate lysine, resulting in an isopeptide bond and the release of phosphate as a good leaving group.

326424:FRAAL RS24175
gene id: 326424:FRAAL_RS24175
uniprot id: Q0RED0
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

326424:FRAAL RS01050
gene id: 326424:FRAAL_RS01050
uniprot id: Q0RU33
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

326424:FRAAL RS11420
gene id: 326424:FRAAL_RS11420
uniprot id: Q0RMI3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

326424:FRAAL RS09070
gene id: 326424:FRAAL_RS09070
uniprot id: Q0RP00
names: Subcellular Location Annotation
messages: Membrane

326424:FRAAL RS30755
gene id: 326424:FRAAL_RS30755
uniprot id: Q0RCU9
names: Similarity
messages: Belongs to the glycosyl hydrolase 30 family.

326424:FRAAL RS07065
gene id: 326424:FRAAL_RS07065
uniprot id: Q0RQ87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 87 family.
messages: Membrane

326424:FRAAL RS05065
gene id: 326424:FRAAL_RS05065
uniprot id: Q0RRJ5
names: Caution
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

326424:FRAAL RS08710
gene id: 326424:FRAAL_RS08710
uniprot id: Q0RP76
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

326424:FRAAL RS15570
gene id: 326424:FRAAL_RS15570
uniprot id: Q0RJV6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

326424:FRAAL RS24615
gene id: 326424:FRAAL_RS24615
uniprot id: Q0RE26
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

326424:FRAAL RS21610
gene id: 326424:FRAAL_RS21610
uniprot id: Q0RFZ4
names: Similarity
messages: Belongs to the SCO1/2 family.

326424:FRAAL RS19450
gene id: 326424:FRAAL_RS19450
uniprot id: Q0RHE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

326424:FRAAL RS15110
gene id: 326424:FRAAL_RS15110
uniprot id: Q0RK52
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

326424:FRAAL RS04705
gene id: 326424:FRAAL_RS04705
uniprot id: Q0RRR8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

326424:FRAAL RS00065
gene id: 326424:FRAAL_RS00065
uniprot id: Q0RUP6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

326424:FRAAL RS08210
gene id: 326424:FRAAL_RS08210
uniprot id: Q0RPI2
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

326424:FRAAL RS26420
gene id: 326424:FRAAL_RS26420
uniprot id: Q0RCZ1
names: Similarity
messages: Belongs to the DEAD box helicase family.

326424:FRAAL RS05235
gene id: 326424:FRAAL_RS05235
uniprot id: Q0RRF7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: Homotrimer.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. Cleaves guanosine, inosine, 2'-deoxyguanosine and 2'-deoxyinosine.

326424:FRAAL RS00530
gene id: 326424:FRAAL_RS00530
uniprot id: Q0RUE9
names: Similarity
messages: Belongs to the citrate synthase family.

326424:FRAAL RS19745
gene id: 326424:FRAAL_RS19745
uniprot id: Q0RH75
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the insertion of ferrous iron into coproporphyrin III to form Fe-coproporphyrin III.

326424:FRAAL RS22405
gene id: 326424:FRAAL_RS22405
uniprot id: Q0RFG5
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

326424:FRAAL RS04545
gene id: 326424:FRAAL_RS04545
uniprot id: Q0RRU7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

326424:FRAAL RS23110
gene id: 326424:FRAAL_RS23110
uniprot id: Q0RF18
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpC family.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

326424:FRAAL RS19420
gene id: 326424:FRAAL_RS19420
uniprot id: Q0RHE6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

326424:FRAAL RS22365
gene id: 326424:FRAAL_RS22365
uniprot id: Q0RFH5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 3 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

326424:FRAAL RS04675
gene id: 326424:FRAAL_RS04675
uniprot id: Q0RRS4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

326424:FRAAL RS12610
gene id: 326424:FRAAL_RS12610
uniprot id: Q0RLS0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

326424:FRAAL RS14675
gene id: 326424:FRAAL_RS14675
uniprot id: Q0RKF1
names: Similarity
messages: Belongs to the cytochrome P450 family.

326424:FRAAL RS17185
gene id: 326424:FRAAL_RS17185
uniprot id: Q0RIU8
names: Subcellular Location Annotation
messages: Membrane

326424:FRAAL RS28515
gene id: 326424:FRAAL_RS28515
uniprot id: Q0RBM4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.
messages: Cytoplasm
messages: Homodimer.

326424:FRAAL RS13695
gene id: 326424:FRAAL_RS13695
uniprot id: Q0RL27
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

326424:FRAAL RS20815
gene id: 326424:FRAAL_RS20815
uniprot id: Q0RGH4
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

326424:FRAAL RS20430
gene id: 326424:FRAAL_RS20430
uniprot id: Q0RGR1
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

326424:FRAAL RS19630
gene id: 326424:FRAAL_RS19630
uniprot id: Q0RHA0
names: Function
names: Similarity
messages: ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
messages: In the N-terminal section; belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.

326424:FRAAL RS06930
gene id: 326424:FRAAL_RS06930
uniprot id: Q0RQB7
names: Function
names: Subcellular Location Annotation
messages: Iron-sulfur subunit of the cytochrome bc1 complex, an essential component of the respiratory electron transport chain required for ATP synthesis. The bc1 complex catalyzes the oxidation of menaquinol and the reduction of cytochrome c in the respiratory chain. The bc1 complex operates through a Q-cycle mechanism that couples electron transfer to generation of the proton gradient that drives ATP synthesis.
messages: Membrane

326424:FRAAL RS26230
gene id: 326424:FRAAL_RS26230
uniprot id: Q0RD28
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

326424:FRAAL RS01705
gene id: 326424:FRAAL_RS01705
uniprot id: Q0RTP2
names: Similarity
messages: Belongs to the group II decarboxylase family.

326424:FRAAL RS12585
gene id: 326424:FRAAL_RS12585
uniprot id: Q0RLS6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

326424:FRAAL RS04630
gene id: 326424:FRAAL_RS04630
uniprot id: Q0RRT5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

326424:FRAAL RS04495
gene id: 326424:FRAAL_RS04495
uniprot id: Q0RRV8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

326424:FRAAL RS17990
gene id: 326424:FRAAL_RS17990
uniprot id: Q0RIB8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

326424:FRAAL RS00385
gene id: 326424:FRAAL_RS00385
uniprot id: Q0RUH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

326424:FRAAL RS26240
gene id: 326424:FRAAL_RS26240
uniprot id: Q0RD26
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

326424:FRAAL RS04720
gene id: 326424:FRAAL_RS04720
uniprot id: Q0RRR5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

326424:FRAAL RS24950
gene id: 326424:FRAAL_RS24950
uniprot id: Q0RDV4
names: Similarity
messages: Belongs to the Dps family.

326424:FRAAL RS04855
gene id: 326424:FRAAL_RS04855
uniprot id: Q0RRN8
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

326424:FRAAL RS08350
gene id: 326424:FRAAL_RS08350
uniprot id: Q0RPF7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

326424:FRAAL RS13090
gene id: 326424:FRAAL_RS13090
uniprot id: Q0RLG2
names: Subcellular Location Annotation
messages: Membrane

326424:FRAAL RS27845
gene id: 326424:FRAAL_RS27845
uniprot id: Q0RC25
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

326424:FRAAL RS02395
gene id: 326424:FRAAL_RS02395
uniprot id: Q0RT75
names: Function
names: Similarity
messages: Belongs to the ApbE family.
messages: Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.

326424:FRAAL RS25385
gene id: 326424:FRAAL_RS25385
uniprot id: Q0RDK7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

326424:FRAAL RS25295
gene id: 326424:FRAAL_RS25295
uniprot id: Q0RDM9
names: Subcellular Location Annotation
messages: Cytoplasm

326424:FRAAL RS22705
gene id: 326424:FRAAL_RS22705
uniprot id: Q0RFA7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

326424:FRAAL RS28040
gene id: 326424:FRAAL_RS28040
uniprot id: Q0RBY2
names: Similarity
messages: Belongs to the IucA/IucC family.

326424:FRAAL RS05945
gene id: 326424:FRAAL_RS05945
uniprot id: Q0RR05
names: Similarity
messages: Belongs to the glycosyl hydrolase 26 family.

326424:FRAAL RS10810
gene id: 326424:FRAAL_RS10810
uniprot id: Q0RMX2
names: Cofactor
names: Similarity
messages: Belongs to the truncated hemoglobin family. Group I subfamily.
messages: Binds 1 heme group per subunit.

326424:FRAAL RS20740
gene id: 326424:FRAAL_RS20740
uniprot id: Q0RGJ0
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

326424:FRAAL RS08370
gene id: 326424:FRAAL_RS08370
uniprot id: Q0RPF3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

326424:FRAAL RS25770
gene id: 326424:FRAAL_RS25770
uniprot id: Q0RDC6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NucS endonuclease family.
messages: Cleaves both 3' and 5' ssDNA extremities of branched DNA structures.
messages: Cytoplasm

326424:FRAAL RS11220
gene id: 326424:FRAAL_RS11220
uniprot id: Q0RMN4
names: Similarity
messages: Belongs to the lysine N(6)-hydroxylase/L-ornithine N(5)-oxygenase family.

326424:FRAAL RS05230
gene id: 326424:FRAAL_RS05230
uniprot id: Q0RRF8
names: Similarity
messages: Belongs to the phosphohexose mutase family.

326424:FRAAL RS06120
gene id: 326424:FRAAL_RS06120
uniprot id: Q0RQW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family.
messages: Membrane

326424:FRAAL RS29130
gene id: 326424:FRAAL_RS29130
uniprot id: Q0RB90
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

326424:FRAAL RS04140
gene id: 326424:FRAAL_RS04140
uniprot id: Q0RS35
names: Function
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

326424:FRAAL RS04865
gene id: 326424:FRAAL_RS04865
uniprot id: Q0RRN6
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

326424:FRAAL RS29925
gene id: 326424:FRAAL_RS29925
uniprot id: Q0RAR5
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

326424:FRAAL RS09580
gene id: 326424:FRAAL_RS09580
uniprot id: Q0RNP5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

326424:FRAAL RS04635
gene id: 326424:FRAAL_RS04635
uniprot id: Q0RRT3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

326424:FRAAL RS02640
gene id: 326424:FRAAL_RS02640
uniprot id: Q0RT19
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

326424:FRAAL RS25380
gene id: 326424:FRAAL_RS25380
uniprot id: Q0RDK8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

326424:FRAAL RS01570
gene id: 326424:FRAAL_RS01570
uniprot id: Q0RTR9
names: Subcellular Location Annotation
messages: Membrane

326424:FRAAL RS07980
gene id: 326424:FRAAL_RS07980
uniprot id: Q0RPN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

326424:FRAAL RS24875
gene id: 326424:FRAAL_RS24875
uniprot id: Q0RDX2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

326424:FRAAL RS07770
gene id: 326424:FRAAL_RS07770
uniprot id: Q0RPS6
names: Similarity
messages: Belongs to the TPP enzyme family.

326424:FRAAL RS14775
gene id: 326424:FRAAL_RS14775
uniprot id: Q0RKD0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

326424:FRAAL RS10190
gene id: 326424:FRAAL_RS10190
uniprot id: Q0RNB1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

326424:FRAAL RS20260
gene id: 326424:FRAAL_RS20260
uniprot id: Q0RGV4
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

326424:FRAAL RS24850
gene id: 326424:FRAAL_RS24850
uniprot id: Q0RDX7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

326424:FRAAL RS34650
gene id: 326424:FRAAL_RS34650
uniprot id: Q0RQK4
names: Similarity
messages: Belongs to the cytochrome P450 family.

326424:FRAAL RS06130
gene id: 326424:FRAAL_RS06130
uniprot id: Q0RQV6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family.
messages: Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).
messages: Binds 1 Mg(2+) ion per subunit.
messages: Monomer.

326424:FRAAL RS04490
gene id: 326424:FRAAL_RS04490
uniprot id: Q0RRV9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

326424:FRAAL RS00300
gene id: 326424:FRAAL_RS00300
uniprot id: Q0RUJ5
names: Cofactor
names: Similarity
messages: Belongs to the nitroreductase family.
messages: Binds 1 FMN per subunit.

326424:FRAAL RS13760
gene id: 326424:FRAAL_RS13760
uniprot id: Q0RL12
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

326424:FRAAL RS18945
gene id: 326424:FRAAL_RS18945
uniprot id: Q70Z02
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

326424:FRAAL RS04560
gene id: 326424:FRAAL_RS04560
uniprot id: Q0RRU5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

326424:FRAAL RS19100
gene id: 326424:FRAAL_RS19100
uniprot id: Q0RHL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

326424:FRAAL RS09010
gene id: 326424:FRAAL_RS09010
uniprot id: Q0RP12
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

326424:FRAAL RS12495
gene id: 326424:FRAAL_RS12495
uniprot id: Q0RLU4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

326424:FRAAL RS26935
gene id: 326424:FRAAL_RS26935
uniprot id: Q0RCM5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

326424:FRAAL RS28400
gene id: 326424:FRAAL_RS28400
uniprot id: Q0RBP8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

326424:FRAAL RS25060
gene id: 326424:FRAAL_RS25060
uniprot id: Q0RDT1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

326424:FRAAL RS05790
gene id: 326424:FRAAL_RS05790
uniprot id: Q0RR41
names: Subcellular Location Annotation
messages: Membrane

326424:FRAAL RS09555
gene id: 326424:FRAAL_RS09555
uniprot id: Q0RNQ0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

326424:FRAAL RS13710
gene id: 326424:FRAAL_RS13710
uniprot id: Q0RL24
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

326424:FRAAL RS15445
gene id: 326424:FRAAL_RS15445
uniprot id: Q0RJY1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

326424:FRAAL RS11050
gene id: 326424:FRAAL_RS11050
uniprot id: Q0RMS4
names: Subcellular Location Annotation
messages: Membrane

326424:FRAAL RS16890
gene id: 326424:FRAAL_RS16890
uniprot id: Q0RJ10
names: Similarity
messages: Belongs to the ketopantoate reductase family.

326424:FRAAL RS24685
gene id: 326424:FRAAL_RS24685
uniprot id: Q0RE12
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

326424:FRAAL RS04310
gene id: 326424:FRAAL_RS04310
uniprot id: Q0RRZ6
names: Subcellular Location Annotation
messages: Membrane

326424:FRAAL RS28630
gene id: 326424:FRAAL_RS28630
uniprot id: Q0RBK0
names: Subcellular Location Annotation
messages: Membrane

326424:FRAAL RS13970
gene id: 326424:FRAAL_RS13970
uniprot id: Q0RKW4
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

326424:FRAAL RS23115
gene id: 326424:FRAAL_RS23115
uniprot id: Q0RF17
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system and for the release of the potassium ions to the cytoplasm.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

326424:FRAAL RS06815
gene id: 326424:FRAAL_RS06815
uniprot id: Q0RQE9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

326424:FRAAL RS10890
gene id: 326424:FRAAL_RS10890
uniprot id: Q0RMV6
names: Similarity
messages: Belongs to the terpene cyclase/mutase family.

326424:FRAAL RS27135
gene id: 326424:FRAAL_RS27135
uniprot id: Q0RCI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Membrane

326424:FRAAL RS13325
gene id: 326424:FRAAL_RS13325
uniprot id: Q0RLB3
names: Cofactor
names: Similarity
messages: Belongs to the carotenoid oxygenase family.
messages: Binds 1 Fe(2+) ion per subunit.

326424:FRAAL RS00305
gene id: 326424:FRAAL_RS00305
uniprot id: Q0RUJ4
names: Subcellular Location Annotation
messages: Membrane

326424:FRAAL RS06400
gene id: 326424:FRAAL_RS06400
uniprot id: Q0RQP8
names: Cofactor
names: Function
messages: Binds 1 [3Fe-4S] cluster.
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

326424:FRAAL RS06415
gene id: 326424:FRAAL_RS06415
uniprot id: Q0RQP5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterioferritin family.
messages: Homooligomer of 24 subunits, arranged as 12 dimers, that are packed together to form an approximately spherical molecule with a central cavity, in which large amounts of iron can be deposited.
messages: Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.

326424:FRAAL RS06290
gene id: 326424:FRAAL_RS06290
uniprot id: Q0RQS0
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
messages: Binds 2 nickel ions per subunit.
messages: Carboxylation allows a single lysine to coordinate two nickel ions.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

326424:FRAAL RS28375
gene id: 326424:FRAAL_RS28375
uniprot id: Q0RBQ4
names: Similarity
messages: Belongs to the terpene synthase family.

326424:FRAAL RS09360
gene id: 326424:FRAAL_RS09360
uniprot id: Q0RNU2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

326424:FRAAL RS04830
gene id: 326424:FRAAL_RS04830
uniprot id: Q0RRP3
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

326424:FRAAL RS04620
gene id: 326424:FRAAL_RS04620
uniprot id: Q0RRT7
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

326424:FRAAL RS21815
gene id: 326424:FRAAL_RS21815
uniprot id: Q0RFU6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

326424:FRAAL RS03065
gene id: 326424:FRAAL_RS03065
uniprot id: Q0RSS6
names: Similarity
messages: Belongs to the CapA family.

326424:FRAAL RS04775
gene id: 326424:FRAAL_RS04775
uniprot id: Q0RRQ4
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

326424:FRAAL RS29245
gene id: 326424:FRAAL_RS29245
uniprot id: Q0RB67
names: Similarity
messages: Belongs to the glycosyltransferase 20 family.

326424:FRAAL RS08735
gene id: 326424:FRAAL_RS08735
uniprot id: Q0RP71
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

326424:FRAAL RS20685
gene id: 326424:FRAAL_RS20685
uniprot id: Q0RGK2
names: Similarity
messages: Belongs to the HSP15 family.

326424:FRAAL RS19645
gene id: 326424:FRAAL_RS19645
uniprot id: Q0RH96
names: Function
names: Similarity
names: Subunit
messages: Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity.
messages: Belongs to the AhpD family.
messages: Homotrimer.

326424:FRAAL RS27195
gene id: 326424:FRAAL_RS27195
uniprot id: Q0RCG8
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

326424:FRAAL RS04760
gene id: 326424:FRAAL_RS04760
uniprot id: Q0RRQ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

326424:FRAAL RS22795
gene id: 326424:FRAAL_RS22795
uniprot id: Q0RF89
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

326424:FRAAL RS17455
gene id: 326424:FRAAL_RS17455
uniprot id: Q0RIP2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

326424:FRAAL RS13245
gene id: 326424:FRAAL_RS13245
uniprot id: Q0RLC9
names: Similarity
messages: Belongs to the Rv1128c/1148c/1588c/1702c/1945/3466 family.

326424:FRAAL RS29710
gene id: 326424:FRAAL_RS29710
uniprot id: Q0RAW3
names: Similarity
messages: Belongs to the NifZ family.

326424:FRAAL RS22150
gene id: 326424:FRAAL_RS22150
uniprot id: Q0RFM2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

326424:FRAAL RS09520
gene id: 326424:FRAAL_RS09520
uniprot id: Q0RNQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. DnaE2 subfamily.
messages: Cytoplasm
messages: DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase.

326424:FRAAL RS28740
gene id: 326424:FRAAL_RS28740
uniprot id: Q0RBH8
names: Similarity
messages: Belongs to the peptidase S13 family.

326424:FRAAL RS14890
gene id: 326424:FRAAL_RS14890
uniprot id: Q0RKA3
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

326424:FRAAL RS30685
gene id: 326424:FRAAL_RS30685
uniprot id: Q0REJ2
names: Subcellular Location Annotation
messages: Membrane

326424:FRAAL RS29590
gene id: 326424:FRAAL_RS29590
uniprot id: Q0RAY7
names: Subcellular Location Annotation
messages: Membrane

326424:FRAAL RS04765
gene id: 326424:FRAAL_RS04765
uniprot id: Q0RRQ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

326424:FRAAL RS17485
gene id: 326424:FRAAL_RS17485
uniprot id: Q0RIN6
names: Subcellular Location Annotation
messages: Membrane

326424:FRAAL RS25175
gene id: 326424:FRAAL_RS25175
uniprot id: Q0RDQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

326424:FRAAL RS09015
gene id: 326424:FRAAL_RS09015
uniprot id: Q0RP11
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 2 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

326424:FRAAL RS13860
gene id: 326424:FRAAL_RS13860
uniprot id: Q0RKY7
names: Similarity
messages: Belongs to the glycosyl hydrolase 26 family.

326424:FRAAL RS25005
gene id: 326424:FRAAL_RS25005
uniprot id: Q0RDU3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mg(2+). Can also accept Mn(2+).

326424:FRAAL RS16850
gene id: 326424:FRAAL_RS16850
uniprot id: Q0RJ18
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

326424:FRAAL RS06475
gene id: 326424:FRAAL_RS06475
uniprot id: Q0RQN2
names: Subcellular Location Annotation
messages: Membrane

326424:FRAAL RS04640
gene id: 326424:FRAAL_RS04640
uniprot id: Q0RRT2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

326424:FRAAL RS10020
gene id: 326424:FRAAL_RS10020
uniprot id: Q0RNE5
names: Subcellular Location Annotation
messages: Membrane

326424:FRAAL RS12640
gene id: 326424:FRAAL_RS12640
uniprot id: Q0RLR4
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

326424:FRAAL RS29580
gene id: 326424:FRAAL_RS29580
uniprot id: Q0RAZ0
names: Subcellular Location Annotation
messages: Membrane

326424:FRAAL RS21700
gene id: 326424:FRAAL_RS21700
uniprot id: Q0RFX6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

326424:FRAAL RS13425
gene id: 326424:FRAAL_RS13425
uniprot id: Q0RL87
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

326424:FRAAL RS17840
gene id: 326424:FRAAL_RS17840
uniprot id: Q0RIF4
names: Similarity
messages: Belongs to the thioesterase family.

326424:FRAAL RS04000
gene id: 326424:FRAAL_RS04000
uniprot id: Q0RS64
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetyltransferase family. MshD subfamily.
messages: Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol.
messages: Monomer.

326424:FRAAL RS25835
gene id: 326424:FRAAL_RS25835
uniprot id: Q0RDB2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

326424:FRAAL RS07860
gene id: 326424:FRAAL_RS07860
uniprot id: Q0RPQ6
names: Similarity
messages: Belongs to the HupF/HypC family.

326424:FRAAL RS17915
gene id: 326424:FRAAL_RS17915
uniprot id: Q0RID4
names: Subcellular Location Annotation
messages: Membrane

326424:FRAAL RS08445
gene id: 326424:FRAAL_RS08445
uniprot id: Q0RPD5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

326424:FRAAL RS18390
gene id: 326424:FRAAL_RS18390
uniprot id: Q0RI24
names: Similarity
messages: Belongs to the cytochrome P450 family.

326424:FRAAL RS28985
gene id: 326424:FRAAL_RS28985
uniprot id: Q0RBC2
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

326424:FRAAL RS28480
gene id: 326424:FRAAL_RS28480
uniprot id: Q0RBN1
names: Similarity
messages: Belongs to the Nth/MutY family.

326424:FRAAL RS26550
gene id: 326424:FRAAL_RS26550
uniprot id: Q0RCW5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.
messages: In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: In the N-terminal section; belongs to the MIP18 family.

326424:FRAAL RS28950
gene id: 326424:FRAAL_RS28950
uniprot id: Q0RBD0
names: Similarity
messages: Belongs to the glycosyl hydrolase 65 family.

326424:FRAAL RS08275
gene id: 326424:FRAAL_RS08275
uniprot id: Q0RPH1
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

326424:FRAAL RS20020
gene id: 326424:FRAAL_RS20020
uniprot id: Q0RH15
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

326424:FRAAL RS16695
gene id: 326424:FRAAL_RS16695
uniprot id: Q0RJ56
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

326424:FRAAL RS24525
gene id: 326424:FRAAL_RS24525
uniprot id: Q0RE47
names: Subcellular Location Annotation
messages: Membrane

326424:FRAAL RS17610
gene id: 326424:FRAAL_RS17610
uniprot id: Q0RIK7
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

326424:FRAAL RS24735
gene id: 326424:FRAAL_RS24735
uniprot id: Q0RE02
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

326424:FRAAL RS25075
gene id: 326424:FRAAL_RS25075
uniprot id: Q0RDS8
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

326424:FRAAL RS26760
gene id: 326424:FRAAL_RS26760
uniprot id: Q0RCR5
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

326424:FRAAL RS29760
gene id: 326424:FRAAL_RS29760
uniprot id: Q0RAV3
names: Function
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.
messages: This protein is a Fe-Mo-cofactor biosynthetic component.

326424:FRAAL RS16965
gene id: 326424:FRAAL_RS16965
uniprot id: Q0RIZ4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.