324925:PPHA RS04850
gene id: 324925:PPHA_RS04850
uniprot id: B4SFK8
names: Similarity
messages: Belongs to the NifH/BchL/ChlL family.

324925:PPHA RS08800
gene id: 324925:PPHA_RS08800
uniprot id: B4SBF7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

324925:PPHA RS02465
gene id: 324925:PPHA_RS02465
uniprot id: B4SCY3
names: Subcellular Location Annotation
messages: Membrane

324925:PPHA RS08900
gene id: 324925:PPHA_RS08900
uniprot id: B4SBH4
names: Function
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family.
messages: Involved in bacteriochlorophyll biosynthesis; introduces a magnesium ion into protoporphyrin IX to yield Mg-protoporphyrin IX.

324925:PPHA RS14440
gene id: 324925:PPHA_RS14440
uniprot id: B4SCU5
names: Similarity
messages: Belongs to the peptidase S8 family.

324925:PPHA RS14305
gene id: 324925:PPHA_RS14305
uniprot id: B4SHF5
names: Function
names: Similarity
messages: Belongs to the transglycosylase MltG family.
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

324925:PPHA RS08235
gene id: 324925:PPHA_RS08235
uniprot id: B4SAV3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

324925:PPHA RS10770
gene id: 324925:PPHA_RS10770
uniprot id: B4SDK8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

324925:PPHA RS07120
gene id: 324925:PPHA_RS07120
uniprot id: B4S9Z4
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA.
messages: Belongs to the helicase family. UvrD subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding. Interacts with RecA.
messages: The C-terminal domain has nuclease activity and interacts with RecD. It interacts with RecA, facilitating its loading onto ssDNA.
messages: The N-terminal DNA-binding domain is a ssDNA-dependent ATPase and has ATP-dependent 3'-5' helicase function. This domain interacts with RecC.

324925:PPHA RS00405
gene id: 324925:PPHA_RS00405
uniprot id: B4SAR8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

324925:PPHA RS02385
gene id: 324925:PPHA_RS02385
uniprot id: B4SCW8
names: Similarity
messages: Belongs to the NadC/ModD family.

324925:PPHA RS14580
gene id: 324925:PPHA_RS14580
uniprot id: B4S9V6
names: Similarity
messages: Belongs to the rubredoxin family.

324925:PPHA RS07215
gene id: 324925:PPHA_RS07215
uniprot id: B4SA14
names: Similarity
messages: Belongs to the HsdR family.

324925:PPHA RS00015
gene id: 324925:PPHA_RS00015
uniprot id: B4SA96
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

324925:PPHA RS10620
gene id: 324925:PPHA_RS10620
uniprot id: B4SD86
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

324925:PPHA RS13710
gene id: 324925:PPHA_RS13710
uniprot id: B4SGJ7
names: Similarity
messages: Belongs to the aminoglycoside phosphotransferase family.
messages: Belongs to the glycosyl hydrolase 13 family. TreS subfamily.

324925:PPHA RS01120
gene id: 324925:PPHA_RS01120
uniprot id: B4SBN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

324925:PPHA RS04635
gene id: 324925:PPHA_RS04635
uniprot id: B4SF74
names: Subcellular Location Annotation
messages: Cytoplasm

324925:PPHA RS01465
gene id: 324925:PPHA_RS01465
uniprot id: B4SBU7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

324925:PPHA RS03825
gene id: 324925:PPHA_RS03825
uniprot id: B4SEH6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

324925:PPHA RS01475
gene id: 324925:PPHA_RS01475
uniprot id: B4SBU9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

324925:PPHA RS08740
gene id: 324925:PPHA_RS08740
uniprot id: B4SBE5
names: Similarity
messages: Belongs to the glutamine synthetase family.

324925:PPHA RS00790
gene id: 324925:PPHA_RS00790
uniprot id: B4SB74
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HCP family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Binds 1 hybrid [4Fe-2O-2S] cluster.
messages: Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
messages: Cytoplasm

324925:PPHA RS14200
gene id: 324925:PPHA_RS14200
uniprot id: B4SH40
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase A chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a, b, b' and c.
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.

324925:PPHA RS01810
gene id: 324925:PPHA_RS01810
uniprot id: B4SCB1
names: Similarity
messages: Belongs to the tRNA methyltransferase O family.

324925:PPHA RS11705
gene id: 324925:PPHA_RS11705
uniprot id: B4SEE1
names: Similarity
messages: Belongs to the peptidase M16 family.

324925:PPHA RS05455
gene id: 324925:PPHA_RS05455
uniprot id: B4SG69
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

324925:PPHA RS10160
gene id: 324925:PPHA_RS10160
uniprot id: B4SCQ1
names: Similarity
messages: Belongs to the HypD family.

324925:PPHA RS02400
gene id: 324925:PPHA_RS02400
uniprot id: B4SCX1
names: Subcellular Location Annotation
messages: Membrane

324925:PPHA RS13020
gene id: 324925:PPHA_RS13020
uniprot id: B4SFX7
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

324925:PPHA RS13250
gene id: 324925:PPHA_RS13250
uniprot id: B4SGB0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

324925:PPHA RS01555
gene id: 324925:PPHA_RS01555
uniprot id: B4SBW4
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

324925:PPHA RS05390
gene id: 324925:PPHA_RS05390
uniprot id: B4SG56
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

324925:PPHA RS03460
gene id: 324925:PPHA_RS03460
uniprot id: B4SE06
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell inner membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

324925:PPHA RS06515
gene id: 324925:PPHA_RS06515
uniprot id: B4SHA7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

324925:PPHA RS02170
gene id: 324925:PPHA_RS02170
uniprot id: B4SCS6
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

324925:PPHA RS00165
gene id: 324925:PPHA_RS00165
uniprot id: B4SAM4
names: Similarity
messages: Belongs to the HdrA family.

324925:PPHA RS13260
gene id: 324925:PPHA_RS13260
uniprot id: B4SGB2
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

324925:PPHA RS00115
gene id: 324925:PPHA_RS00115
uniprot id: B4SAL4
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

324925:PPHA RS06135
gene id: 324925:PPHA_RS06135
uniprot id: B4SGT9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

324925:PPHA RS00965
gene id: 324925:PPHA_RS00965
uniprot id: B4SBA3
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

324925:PPHA RS13675
gene id: 324925:PPHA_RS13675
uniprot id: B4SGJ0
names: Subcellular Location Annotation
messages: Membrane

324925:PPHA RS13845
gene id: 324925:PPHA_RS13845
uniprot id: B4SGX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

324925:PPHA RS06785
gene id: 324925:PPHA_RS06785
uniprot id: B4S9T3
names: Similarity
messages: Belongs to the peptidase S41A family.

324925:PPHA RS07650
gene id: 324925:PPHA_RS07650
uniprot id: B4SAA7
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

324925:PPHA RS01565
gene id: 324925:PPHA_RS01565
uniprot id: B4SBW6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

324925:PPHA RS10920
gene id: 324925:PPHA_RS10920
uniprot id: B4SDN6
names: Similarity
messages: Belongs to the RecJ family.

324925:PPHA RS12275
gene id: 324925:PPHA_RS12275
uniprot id: B4SF92
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

324925:PPHA RS04355
gene id: 324925:PPHA_RS04355
uniprot id: B4SF20
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

324925:PPHA RS13685
gene id: 324925:PPHA_RS13685
uniprot id: B4SGJ2
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

324925:PPHA RS14245
gene id: 324925:PPHA_RS14245
uniprot id: B4SH49
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell inner membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).

324925:PPHA RS01050
gene id: 324925:PPHA_RS01050
uniprot id: B4SBC1
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

324925:PPHA RS02120
gene id: 324925:PPHA_RS02120
uniprot id: B4SCR7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

324925:PPHA RS06025
gene id: 324925:PPHA_RS06025
uniprot id: B4SGR7
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

324925:PPHA RS03325
gene id: 324925:PPHA_RS03325
uniprot id: B4SDY0
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

324925:PPHA RS07165
gene id: 324925:PPHA_RS07165
uniprot id: B4SA03
names: Similarity
messages: Belongs to the YoeB family.

324925:PPHA RS04185
gene id: 324925:PPHA_RS04185
uniprot id: B4SEZ0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

324925:PPHA RS07775
gene id: 324925:PPHA_RS07775
uniprot id: B4SAC8
names: Similarity
messages: Belongs to the universal stress protein A family.

324925:PPHA RS09855
gene id: 324925:PPHA_RS09855
uniprot id: B4SCJ6
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily.

324925:PPHA RS10410
gene id: 324925:PPHA_RS10410
uniprot id: B4SD44
names: Similarity
messages: Belongs to the TrpF family.

324925:PPHA RS00890
gene id: 324925:PPHA_RS00890
uniprot id: B4SB91
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

324925:PPHA RS03580
gene id: 324925:PPHA_RS03580
uniprot id: B4SE29
names: Similarity
messages: Belongs to the CarB family.

324925:PPHA RS02060
gene id: 324925:PPHA_RS02060
uniprot id: B4SCG0
names: Similarity
messages: Belongs to the DprA/Smf family.

324925:PPHA RS00395
gene id: 324925:PPHA_RS00395
uniprot id: B4SAR7
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).

324925:PPHA RS10255
gene id: 324925:PPHA_RS10255
uniprot id: B4SD19
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

324925:PPHA RS12135
gene id: 324925:PPHA_RS12135
uniprot id: B4SEW7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

324925:PPHA RS10475
gene id: 324925:PPHA_RS10475
uniprot id: B4SD58
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

324925:PPHA RS12830
gene id: 324925:PPHA_RS12830
uniprot id: B4SFU1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

324925:PPHA RS03610
gene id: 324925:PPHA_RS03610
uniprot id: B4SE35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

324925:PPHA RS01610
gene id: 324925:PPHA_RS01610
uniprot id: B4SC70
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

324925:PPHA RS10570
gene id: 324925:PPHA_RS10570
uniprot id: B4SD78
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

324925:PPHA RS00885
gene id: 324925:PPHA_RS00885
uniprot id: B4SB90
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

324925:PPHA RS07770
gene id: 324925:PPHA_RS07770
uniprot id: B4SAC7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I fumarase family.
messages: Catalyzes the reversible hydration of fumarate to (S)-malate.
messages: Homodimer.

324925:PPHA RS13360
gene id: 324925:PPHA_RS13360
uniprot id: B4SGD1
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

324925:PPHA RS12955
gene id: 324925:PPHA_RS12955
uniprot id: B4SFW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0014 family.
messages: Membrane

324925:PPHA RS07235
gene id: 324925:PPHA_RS07235
uniprot id: B4SA18
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

324925:PPHA RS12635
gene id: 324925:PPHA_RS12635
uniprot id: B4SFF1
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

324925:PPHA RS13875
gene id: 324925:PPHA_RS13875
uniprot id: B4SGX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

324925:PPHA RS01980
gene id: 324925:PPHA_RS01980
uniprot id: B4SCE5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

324925:PPHA RS13790
gene id: 324925:PPHA_RS13790
uniprot id: B4SGW1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

324925:PPHA RS13320
gene id: 324925:PPHA_RS13320
uniprot id: B4SGC3
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

324925:PPHA RS01995
gene id: 324925:PPHA_RS01995
uniprot id: B4SCE8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

324925:PPHA RS04360
gene id: 324925:PPHA_RS04360
uniprot id: B4SF21
names: Cofactor
names: Similarity
messages: Belongs to the PdaD family.
messages: Belongs to the pyruvoyl-dependent arginine decarboxylase family.
messages: Binds 1 pyruvoyl group covalently per subunit.

324925:PPHA RS01485
gene id: 324925:PPHA_RS01485
uniprot id: B4SBV1
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

324925:PPHA RS10710
gene id: 324925:PPHA_RS10710
uniprot id: B4SDA4
names: Similarity
messages: Belongs to the Pal lipoprotein family.

324925:PPHA RS01550
gene id: 324925:PPHA_RS01550
uniprot id: B4SBW3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

324925:PPHA RS09655
gene id: 324925:PPHA_RS09655
uniprot id: B4SC59
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the NifH/BchL/ChlL family.
messages: Binds 1 [4Fe-4S] cluster per dimer.
messages: Homodimer.
messages: The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein.
messages: The reversible ADP-ribosylation of Arg-97 inactivates the nitrogenase reductase and regulates nitrogenase activity.

324925:PPHA RS07495
gene id: 324925:PPHA_RS07495
uniprot id: B4SA65
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

324925:PPHA RS03830
gene id: 324925:PPHA_RS03830
uniprot id: B4SEH7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

324925:PPHA RS06770
gene id: 324925:PPHA_RS06770
uniprot id: B4S9T0
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

324925:PPHA RS08055
gene id: 324925:PPHA_RS08055
uniprot id: B4SAH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

324925:PPHA RS08965
gene id: 324925:PPHA_RS08965
uniprot id: B4SBI7
names: Function
names: Subcellular Location Annotation
messages: May play a structural or regulatory role in gas vesicle synthesis.
messages: Vesicle
messages: gas vesicle

324925:PPHA RS03200
gene id: 324925:PPHA_RS03200
uniprot id: B4SDV5
names: Similarity
messages: Belongs to the GARS family.

324925:PPHA RS02205
gene id: 324925:PPHA_RS02205
uniprot id: B4SCT3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

324925:PPHA RS11640
gene id: 324925:PPHA_RS11640
uniprot id: B4SEC8
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

324925:PPHA RS09520
gene id: 324925:PPHA_RS09520
uniprot id: B4SC37
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

324925:PPHA RS00880
gene id: 324925:PPHA_RS00880
uniprot id: B4SB89
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

324925:PPHA RS02655
gene id: 324925:PPHA_RS02655
uniprot id: B4SDB6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

324925:PPHA RS14220
gene id: 324925:PPHA_RS14220
uniprot id: B4SH44
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

324925:PPHA RS03845
gene id: 324925:PPHA_RS03845
uniprot id: B4SEI0
names: Function
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

324925:PPHA RS06470
gene id: 324925:PPHA_RS06470
uniprot id: B4SH98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the kinesin light chain family.
messages: cytoskeleton

324925:PPHA RS03415
gene id: 324925:PPHA_RS03415
uniprot id: B4SDZ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

324925:PPHA RS01695
gene id: 324925:PPHA_RS01695
uniprot id: B4SC87
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
messages: Cytoplasm
messages: Homotrimer.
messages: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

324925:PPHA RS06520
gene id: 324925:PPHA_RS06520
uniprot id: B4SHA8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

324925:PPHA RS08320
gene id: 324925:PPHA_RS08320
uniprot id: B4SAX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane

324925:PPHA RS10960
gene id: 324925:PPHA_RS10960
uniprot id: B4SDP4
names: Similarity
messages: Belongs to the arsA ATPase family.

324925:PPHA RS11120
gene id: 324925:PPHA_RS11120
uniprot id: B4SDS7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell inner membrane

324925:PPHA RS04230
gene id: 324925:PPHA_RS04230
uniprot id: B4SEZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm

324925:PPHA RS01635
gene id: 324925:PPHA_RS01635
uniprot id: B4SC75
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

324925:PPHA RS05765
gene id: 324925:PPHA_RS05765
uniprot id: B4SGL8
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

324925:PPHA RS05800
gene id: 324925:PPHA_RS05800
uniprot id: B4SGM5
names: Subcellular Location Annotation
messages: chloroplast

324925:PPHA RS00130
gene id: 324925:PPHA_RS00130
uniprot id: B4SAL7
names: Similarity
messages: Belongs to the geranylgeranyl reductase family. ChlP subfamily.

324925:PPHA RS09215
gene id: 324925:PPHA_RS09215
uniprot id: B4SBY6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell inner membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

324925:PPHA RS00900
gene id: 324925:PPHA_RS00900
uniprot id: B4SB93
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged L-seryl-tRNA(Thr).
messages: Cytoplasm
messages: Homodimer.

324925:PPHA RS04615
gene id: 324925:PPHA_RS04615
uniprot id: B4SF70
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

324925:PPHA RS12735
gene id: 324925:PPHA_RS12735
uniprot id: B4SFH0
names: Similarity
messages: Belongs to the phD/YefM antitoxin family.

324925:PPHA RS07825
gene id: 324925:PPHA_RS07825
uniprot id: B4SAD7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

324925:PPHA RS13890
gene id: 324925:PPHA_RS13890
uniprot id: B4SGY1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

324925:PPHA RS01440
gene id: 324925:PPHA_RS01440
uniprot id: B4SBU2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

324925:PPHA RS01270
gene id: 324925:PPHA_RS01270
uniprot id: B4SBR2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

324925:PPHA RS02875
gene id: 324925:PPHA_RS02875
uniprot id: B4SDF2
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

324925:PPHA RS01600
gene id: 324925:PPHA_RS01600
uniprot id: B4SBX3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

324925:PPHA RS10950
gene id: 324925:PPHA_RS10950
uniprot id: B4SDP2
names: Cofactor
names: Similarity
messages: Belongs to the monomeric-type IDH family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

324925:PPHA RS08125
gene id: 324925:PPHA_RS08125
uniprot id: B4SAJ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

324925:PPHA RS13960
gene id: 324925:PPHA_RS13960
uniprot id: B4SGZ3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

324925:PPHA RS13285
gene id: 324925:PPHA_RS13285
uniprot id: B4SGB7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

324925:PPHA RS06435
gene id: 324925:PPHA_RS06435
uniprot id: B4SH91
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

324925:PPHA RS01490
gene id: 324925:PPHA_RS01490
uniprot id: B4SBV2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity).

324925:PPHA RS03340
gene id: 324925:PPHA_RS03340
uniprot id: B4SDY3
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

324925:PPHA RS10790
gene id: 324925:PPHA_RS10790
uniprot id: B4SDL2
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

324925:PPHA RS11115
gene id: 324925:PPHA_RS11115
uniprot id: B4SDS6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

324925:PPHA RS00080
gene id: 324925:PPHA_RS00080
uniprot id: B4SAK7
names: Similarity
messages: Belongs to the UPF0102 family.

324925:PPHA RS01680
gene id: 324925:PPHA_RS01680
uniprot id: B4SC84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gmhB family.
messages: Cytoplasm

324925:PPHA RS02380
gene id: 324925:PPHA_RS02380
uniprot id: B4SCW7
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

324925:PPHA RS00590
gene id: 324925:PPHA_RS00590
uniprot id: B4SB43
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

324925:PPHA RS13220
gene id: 324925:PPHA_RS13220
uniprot id: B4SG17
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell inner membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

324925:PPHA RS12645
gene id: 324925:PPHA_RS12645
uniprot id: B4SFF3
names: Similarity
messages: Belongs to the arsA ATPase family.

324925:PPHA RS05570
gene id: 324925:PPHA_RS05570
uniprot id: B4SG90
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

324925:PPHA RS04945
gene id: 324925:PPHA_RS04945
uniprot id: B4SFM7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

324925:PPHA RS03435
gene id: 324925:PPHA_RS03435
uniprot id: B4SE01
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

324925:PPHA RS03550
gene id: 324925:PPHA_RS03550
uniprot id: B4SE23
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).

324925:PPHA RS06020
gene id: 324925:PPHA_RS06020
uniprot id: B4SGR6
names: Similarity
messages: Belongs to the sigma-54 factor family.

324925:PPHA RS07565
gene id: 324925:PPHA_RS07565
uniprot id: B4SA79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

324925:PPHA RS13615
gene id: 324925:PPHA_RS13615
uniprot id: B4SGH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

324925:PPHA RS00225
gene id: 324925:PPHA_RS00225
uniprot id: B4SAN6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a(1), b(1), b'(1) and c(9-12).
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

324925:PPHA RS01455
gene id: 324925:PPHA_RS01455
uniprot id: B4SBU5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

324925:PPHA RS14190
gene id: 324925:PPHA_RS14190
uniprot id: B4SH38
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell inner membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has four main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains (By similarity).

324925:PPHA RS01685
gene id: 324925:PPHA_RS01685
uniprot id: B4SC85
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

324925:PPHA RS03565
gene id: 324925:PPHA_RS03565
uniprot id: B4SE26
names: Function
names: Similarity
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

324925:PPHA RS02445
gene id: 324925:PPHA_RS02445
uniprot id: B4SCX9
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

324925:PPHA RS04610
gene id: 324925:PPHA_RS04610
uniprot id: B4SF69
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

324925:PPHA RS13140
gene id: 324925:PPHA_RS13140
uniprot id: B4SG00
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

324925:PPHA RS04025
gene id: 324925:PPHA_RS04025
uniprot id: B4SEL4
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

324925:PPHA RS03410
gene id: 324925:PPHA_RS03410
uniprot id: B4SDZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

324925:PPHA RS03115
gene id: 324925:PPHA_RS03115
uniprot id: B4SDJ0
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.

324925:PPHA RS03445
gene id: 324925:PPHA_RS03445
uniprot id: B4SE03
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

324925:PPHA RS09685
gene id: 324925:PPHA_RS09685
uniprot id: B4SC65
names: Similarity
messages: Belongs to the NifD/NifK/NifE/NifN family.

324925:PPHA RS05950
gene id: 324925:PPHA_RS05950
uniprot id: B4SGQ3
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

324925:PPHA RS04295
gene id: 324925:PPHA_RS04295
uniprot id: B4SF08
names: Similarity
messages: Belongs to the GroES chaperonin family.

324925:PPHA RS01630
gene id: 324925:PPHA_RS01630
uniprot id: B4SC74
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

324925:PPHA RS03080
gene id: 324925:PPHA_RS03080
uniprot id: B4SDI4
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

324925:PPHA RS13180
gene id: 324925:PPHA_RS13180
uniprot id: B4SG09
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

324925:PPHA RS08045
gene id: 324925:PPHA_RS08045
uniprot id: B4SAH6
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

324925:PPHA RS08675
gene id: 324925:PPHA_RS08675
uniprot id: B4SBD2
names: Cofactor
names: PTM
names: Subcellular Location Annotation
messages: Binds 2 heme groups per subunit.
messages: Binds 2 heme groups.
messages: Periplasm

324925:PPHA RS00905
gene id: 324925:PPHA_RS00905
uniprot id: B4SB94
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ChlB/BchB/BchZ family.
messages: Chlorophyllide reductase is composed of three subunits; BchX, BchY and BchZ. Forms a heterodimer of one BchY and one BchZ subunit.
messages: Converts chlorophylls (Chl) into bacteriochlorophylls (BChl) by reducing ring B of the tetrapyrrole.

324925:PPHA RS08075
gene id: 324925:PPHA_RS08075
uniprot id: B4SAI2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

324925:PPHA RS12255
gene id: 324925:PPHA_RS12255
uniprot id: B4SF88
names: Similarity
messages: Belongs to the 6-phosphogluconate dehydrogenase family.

324925:PPHA RS05030
gene id: 324925:PPHA_RS05030
uniprot id: B4SFP4
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

324925:PPHA RS01495
gene id: 324925:PPHA_RS01495
uniprot id: B4SBV3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

324925:PPHA RS10180
gene id: 324925:PPHA_RS10180
uniprot id: B4SCQ5
names: Function
names: Similarity
messages: Belongs to the HypA/HybF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.

324925:PPHA RS08585
gene id: 324925:PPHA_RS08585
uniprot id: B4SB22
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

324925:PPHA RS02490
gene id: 324925:PPHA_RS02490
uniprot id: B4SCY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

324925:PPHA RS13760
gene id: 324925:PPHA_RS13760
uniprot id: B4SGV5
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

324925:PPHA RS07530
gene id: 324925:PPHA_RS07530
uniprot id: B4SA72
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

324925:PPHA RS06755
gene id: 324925:PPHA_RS06755
uniprot id: B4S9S7
names: Similarity
messages: Belongs to the LacAB/RpiB family.

324925:PPHA RS08955
gene id: 324925:PPHA_RS08955
uniprot id: B4SBI5
names: Function
names: Subcellular Location Annotation
messages: May play a structural or regulatory role in gas vesicle synthesis.
messages: Vesicle
messages: gas vesicle

324925:PPHA RS04505
gene id: 324925:PPHA_RS04505
uniprot id: B4SF50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

324925:PPHA RS09205
gene id: 324925:PPHA_RS09205
uniprot id: B4SBY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

324925:PPHA RS09200
gene id: 324925:PPHA_RS09200
uniprot id: B4SBY3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell inner membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

324925:PPHA RS09680
gene id: 324925:PPHA_RS09680
uniprot id: B4SC64
names: Function
names: Similarity
messages: Belongs to the NifD/NifK/NifE/NifN family.
messages: This protein may play a role in the biosynthesis of the prosthetic group of nitrogenase (FeMo cofactor).

324925:PPHA RS10955
gene id: 324925:PPHA_RS10955
uniprot id: B4SDP3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

324925:PPHA RS04600
gene id: 324925:PPHA_RS04600
uniprot id: B4SF67
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

324925:PPHA RS11710
gene id: 324925:PPHA_RS11710
uniprot id: B4SEE2
names: Subcellular Location Annotation
messages: Membrane

324925:PPHA RS13840
gene id: 324925:PPHA_RS13840
uniprot id: B4SGX1
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Homotetramer.

324925:PPHA RS01115
gene id: 324925:PPHA_RS01115
uniprot id: B4SBN0
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

324925:PPHA RS12045
gene id: 324925:PPHA_RS12045
uniprot id: B4SEU9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

324925:PPHA RS04290
gene id: 324925:PPHA_RS04290
uniprot id: B4SF07
names: Similarity
messages: Belongs to the MreC family.

324925:PPHA RS06625
gene id: 324925:PPHA_RS06625
uniprot id: B4SHC8
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

324925:PPHA RS03470
gene id: 324925:PPHA_RS03470
uniprot id: B4SE08
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

324925:PPHA RS13485
gene id: 324925:PPHA_RS13485
uniprot id: B4SGF5
names: Subcellular Location Annotation
messages: Membrane

324925:PPHA RS10670
gene id: 324925:PPHA_RS10670
uniprot id: B4SD96
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

324925:PPHA RS05360
gene id: 324925:PPHA_RS05360
uniprot id: B4SG50
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.

324925:PPHA RS09020
gene id: 324925:PPHA_RS09020
uniprot id: B4SBJ5
names: Function
names: Similarity
messages: Belongs to the gas vesicle protein type A family.
messages: Gas vesicles are small, hollow, gas filled protein structures that are found in several microbial planktonic microorganisms. They allow the positioning of the organism at the favorable depth for growth.

324925:PPHA RS10900
gene id: 324925:PPHA_RS10900
uniprot id: B4SDN2
names: Subcellular Location Annotation
messages: Membrane

324925:PPHA RS01505
gene id: 324925:PPHA_RS01505
uniprot id: B4SBV5
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

324925:PPHA RS02000
gene id: 324925:PPHA_RS02000
uniprot id: B4SCE9
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

324925:PPHA RS12655
gene id: 324925:PPHA_RS12655
uniprot id: B4SFF5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BChl C/E-binding protein family.
messages: Component of the photosynthetic apparatus.
messages: chlorosome envelope

324925:PPHA RS05730
gene id: 324925:PPHA_RS05730
uniprot id: B4SGL0
names: Similarity
messages: Belongs to the peptidase S11 family.

324925:PPHA RS02495
gene id: 324925:PPHA_RS02495
uniprot id: B4SCY9
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

324925:PPHA RS14215
gene id: 324925:PPHA_RS14215
uniprot id: B4SH43
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

324925:PPHA RS11650
gene id: 324925:PPHA_RS11650
uniprot id: B4SED0
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

324925:PPHA RS06500
gene id: 324925:PPHA_RS06500
uniprot id: B4SHA4
names: Similarity
messages: Belongs to the HdrA family.

324925:PPHA RS13695
gene id: 324925:PPHA_RS13695
uniprot id: B4SGJ4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

324925:PPHA RS14230
gene id: 324925:PPHA_RS14230
uniprot id: B4SH46
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell inner membrane
messages: Self-interacts. Interacts with FtsZ.

324925:PPHA RS00265
gene id: 324925:PPHA_RS00265
uniprot id: B4SAP4
names: Subcellular Location Annotation
messages: Membrane

324925:PPHA RS14260
gene id: 324925:PPHA_RS14260
uniprot id: B4SHE7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell inner membrane

324925:PPHA RS00475
gene id: 324925:PPHA_RS00475
uniprot id: B4SAT2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein L14 (rplN).

324925:PPHA RS09220
gene id: 324925:PPHA_RS09220
uniprot id: B4SBY7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

324925:PPHA RS10220
gene id: 324925:PPHA_RS10220
uniprot id: B4SCR5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

324925:PPHA RS06900
gene id: 324925:PPHA_RS06900
uniprot id: B4S9V7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDT1 family.
messages: Membrane

324925:PPHA RS01015
gene id: 324925:PPHA_RS01015
uniprot id: B4SBB3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

324925:PPHA RS08240
gene id: 324925:PPHA_RS08240
uniprot id: B4SAV4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

324925:PPHA RS07490
gene id: 324925:PPHA_RS07490
uniprot id: B4SA64
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Monomer.

324925:PPHA RS10990
gene id: 324925:PPHA_RS10990
uniprot id: B4SDQ0
names: Similarity
messages: Belongs to the UPF0047 family.

324925:PPHA RS02595
gene id: 324925:PPHA_RS02595
uniprot id: B4SD09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the etk/wzc family.
messages: Cell inner membrane
messages: Membrane

324925:PPHA RS06480
gene id: 324925:PPHA_RS06480
uniprot id: B4SHA0
names: Cofactor
names: Similarity
messages: Belongs to the PyrK family.
messages: Binds 1 [2Fe-2S] cluster per subunit.

324925:PPHA RS13335
gene id: 324925:PPHA_RS13335
uniprot id: B4SGC6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

324925:PPHA RS06740
gene id: 324925:PPHA_RS06740
uniprot id: B4S9S4
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

324925:PPHA RS02020
gene id: 324925:PPHA_RS02020
uniprot id: B4SCF2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

324925:PPHA RS03850
gene id: 324925:PPHA_RS03850
uniprot id: B4SEI1
names: Similarity
messages: Belongs to the glutamate synthase family.

324925:PPHA RS07505
gene id: 324925:PPHA_RS07505
uniprot id: B4SA67
names: Subcellular Location Annotation
messages: Membrane

324925:PPHA RS04255
gene id: 324925:PPHA_RS04255
uniprot id: B4SF00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

324925:PPHA RS09015
gene id: 324925:PPHA_RS09015
uniprot id: B4SBJ5
names: Function
names: Similarity
messages: Belongs to the gas vesicle protein type A family.
messages: Gas vesicles are small, hollow, gas filled protein structures that are found in several microbial planktonic microorganisms. They allow the positioning of the organism at the favorable depth for growth.

324925:PPHA RS08995
gene id: 324925:PPHA_RS08995
uniprot id: B4SBJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CbbQ/NirQ/NorQ/GpvN family.
messages: Vesicle
messages: gas vesicle

324925:PPHA RS03495
gene id: 324925:PPHA_RS03495
uniprot id: B4SE13
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.

324925:PPHA RS01580
gene id: 324925:PPHA_RS01580
uniprot id: B4SBW9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

324925:PPHA RS14605
gene id: 324925:PPHA_RS14605
uniprot id: B4SA10
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

324925:PPHA RS14395
gene id: 324925:PPHA_RS14395
uniprot id: B4SHH2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

324925:PPHA RS00305
gene id: 324925:PPHA_RS00305
uniprot id: B4SAQ1
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

324925:PPHA RS03365
gene id: 324925:PPHA_RS03365
uniprot id: B4SDY7
names: Function
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.

324925:PPHA RS06910
gene id: 324925:PPHA_RS06910
uniprot id: B4S9V9
names: Similarity
messages: In the C-terminal section; belongs to the succinate/malate CoA ligase alpha subunit family.
messages: In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family.

324925:PPHA RS10645
gene id: 324925:PPHA_RS10645
uniprot id: B4SD91
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

324925:PPHA RS10735
gene id: 324925:PPHA_RS10735
uniprot id: B4SDK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM19 family.
messages: Membrane

324925:PPHA RS04075
gene id: 324925:PPHA_RS04075
uniprot id: B4SEM4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

324925:PPHA RS12875
gene id: 324925:PPHA_RS12875
uniprot id: B4SFU9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

324925:PPHA RS09320
gene id: 324925:PPHA_RS09320
uniprot id: B4SC05
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

324925:PPHA RS10715
gene id: 324925:PPHA_RS10715
uniprot id: B4SDA5
names: Similarity
messages: Belongs to the TolB family.

324925:PPHA RS03600
gene id: 324925:PPHA_RS03600
uniprot id: B4SE33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

324925:PPHA RS01275
gene id: 324925:PPHA_RS01275
uniprot id: B4SBR3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

324925:PPHA RS12145
gene id: 324925:PPHA_RS12145
uniprot id: B4SEW9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

324925:PPHA RS07075
gene id: 324925:PPHA_RS07075
uniprot id: B4S9Y7
names: Function
names: Similarity
messages: Belongs to the RecD family. RecD-like subfamily.
messages: DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity.

324925:PPHA RS08835
gene id: 324925:PPHA_RS08835
uniprot id: B4SBG4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell inner membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

324925:PPHA RS12850
gene id: 324925:PPHA_RS12850
uniprot id: B4SFU5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell inner membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

324925:PPHA RS14095
gene id: 324925:PPHA_RS14095
uniprot id: B4SH22
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

324925:PPHA RS03595
gene id: 324925:PPHA_RS03595
uniprot id: B4SE32
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

324925:PPHA RS07080
gene id: 324925:PPHA_RS07080
uniprot id: B4S9Y8
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

324925:PPHA RS02375
gene id: 324925:PPHA_RS02375
uniprot id: B4SCW6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

324925:PPHA RS02405
gene id: 324925:PPHA_RS02405
uniprot id: B4SCX2
names: Similarity
messages: Belongs to the leucine-binding protein family.

324925:PPHA RS03485
gene id: 324925:PPHA_RS03485
uniprot id: B4SE11
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

324925:PPHA RS11380
gene id: 324925:PPHA_RS11380
uniprot id: B4SE79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Membrane

324925:PPHA RS07585
gene id: 324925:PPHA_RS07585
uniprot id: B4SA83
names: Subcellular Location Annotation
messages: Membrane

324925:PPHA RS13165
gene id: 324925:PPHA_RS13165
uniprot id: B4SG05
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

324925:PPHA RS12250
gene id: 324925:PPHA_RS12250
uniprot id: B4SF87
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

324925:PPHA RS00390
gene id: 324925:PPHA_RS00390
uniprot id: B4SAR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

324925:PPHA RS12230
gene id: 324925:PPHA_RS12230
uniprot id: B4SF83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Membrane

324925:PPHA RS13740
gene id: 324925:PPHA_RS13740
uniprot id: B4SGK3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell inner membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.

324925:PPHA RS00220
gene id: 324925:PPHA_RS00220
uniprot id: B4SAN5
names: Similarity
messages: Belongs to the ATPase epsilon chain family.

324925:PPHA RS05550
gene id: 324925:PPHA_RS05550
uniprot id: B4SG87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

324925:PPHA RS10870
gene id: 324925:PPHA_RS10870
uniprot id: B4SDM6
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family. N(4) subfamily.

324925:PPHA RS11315
gene id: 324925:PPHA_RS11315
uniprot id: B4SE66
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

324925:PPHA RS11260
gene id: 324925:PPHA_RS11260
uniprot id: B4SE56
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

324925:PPHA RS03255
gene id: 324925:PPHA_RS03255
uniprot id: B4SDW6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RuvC family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.

324925:PPHA RS07465
gene id: 324925:PPHA_RS07465
uniprot id: B4SA59
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

324925:PPHA RS04605
gene id: 324925:PPHA_RS04605
uniprot id: B4SF68
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Cytoplasm
messages: Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.

324925:PPHA RS03250
gene id: 324925:PPHA_RS03250
uniprot id: B4SDW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

324925:PPHA RS13815
gene id: 324925:PPHA_RS13815
uniprot id: B4SGW6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

324925:PPHA RS05780
gene id: 324925:PPHA_RS05780
uniprot id: B4SGM1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

324925:PPHA RS09670
gene id: 324925:PPHA_RS09670
uniprot id: B4SC62
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NifD/NifK/NifE/NifN family.
messages: Tetramer of two alpha and two beta chains. Forms complex with the iron protein (nitrogenase component 2).
messages: This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation.

324925:PPHA RS05785
gene id: 324925:PPHA_RS05785
uniprot id: B4SGM2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-insensitive subfamily.
messages: Cell inner membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force.

324925:PPHA RS08020
gene id: 324925:PPHA_RS08020
uniprot id: B4SAH1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.

324925:PPHA RS00970
gene id: 324925:PPHA_RS00970
uniprot id: B4SBA4
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

324925:PPHA RS10925
gene id: 324925:PPHA_RS10925
uniprot id: B4SDN7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.

324925:PPHA RS07670
gene id: 324925:PPHA_RS07670
uniprot id: B4SAB1
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

324925:PPHA RS11625
gene id: 324925:PPHA_RS11625
uniprot id: B4SEC5
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by GTP. Inhibited by UTP.
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

324925:PPHA RS08150
gene id: 324925:PPHA_RS08150
uniprot id: B4SAJ7
names: Subcellular Location Annotation
messages: Membrane

324925:PPHA RS05385
gene id: 324925:PPHA_RS05385
uniprot id: B4SG55
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

324925:PPHA RS09360
gene id: 324925:PPHA_RS09360
uniprot id: B4SC13
names: Similarity
messages: Belongs to the universal stress protein A family.

324925:PPHA RS02305
gene id: 324925:PPHA_RS02305
uniprot id: B4SCV3
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

324925:PPHA RS00665
gene id: 324925:PPHA_RS00665
uniprot id: B4SB54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

324925:PPHA RS13980
gene id: 324925:PPHA_RS13980
uniprot id: B4SGZ7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

324925:PPHA RS03640
gene id: 324925:PPHA_RS03640
uniprot id: B4SE41
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

324925:PPHA RS01735
gene id: 324925:PPHA_RS01735
uniprot id: B4SC95
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

324925:PPHA RS01710
gene id: 324925:PPHA_RS01710
uniprot id: B4SC90
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

324925:PPHA RS13410
gene id: 324925:PPHA_RS13410
uniprot id: B4SGE2
names: Similarity
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.

324925:PPHA RS10760
gene id: 324925:PPHA_RS10760
uniprot id: B4SDK6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

324925:PPHA RS01870
gene id: 324925:PPHA_RS01870
uniprot id: B4SCC3
names: Subcellular Location Annotation
messages: Cytoplasm

324925:PPHA RS12025
gene id: 324925:PPHA_RS12025
uniprot id: B4SEU5
names: Caution
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
messages: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

324925:PPHA RS05855
gene id: 324925:PPHA_RS05855
uniprot id: B4SGN6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

324925:PPHA RS06070
gene id: 324925:PPHA_RS06070
uniprot id: B4SGS6
names: Similarity
messages: Belongs to the HsdR family.

324925:PPHA RS00915
gene id: 324925:PPHA_RS00915
uniprot id: B4SB96
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. C-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

324925:PPHA RS00315
gene id: 324925:PPHA_RS00315
uniprot id: B4SAQ3
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

324925:PPHA RS00085
gene id: 324925:PPHA_RS00085
uniprot id: B4SAK8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

324925:PPHA RS11535
gene id: 324925:PPHA_RS11535
uniprot id: B4SEA9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

324925:PPHA RS03190
gene id: 324925:PPHA_RS03190
uniprot id: B4SDV3
names: Function
names: Similarity
messages: Belongs to the LpxK family.
messages: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

324925:PPHA RS11935
gene id: 324925:PPHA_RS11935
uniprot id: B4SES8
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

324925:PPHA RS12590
gene id: 324925:PPHA_RS12590
uniprot id: B4SFE2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

324925:PPHA RS05600
gene id: 324925:PPHA_RS05600
uniprot id: B4SG96
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

324925:PPHA RS00075
gene id: 324925:PPHA_RS00075
uniprot id: B4SAK6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

324925:PPHA RS13245
gene id: 324925:PPHA_RS13245
uniprot id: B4SGA9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

324925:PPHA RS08160
gene id: 324925:PPHA_RS08160
uniprot id: B4SAJ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

324925:PPHA RS10340
gene id: 324925:PPHA_RS10340
uniprot id: B4SD36
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase Y family.
messages: Cell membrane
messages: Endoribonuclease that initiates mRNA decay.

324925:PPHA RS07655
gene id: 324925:PPHA_RS07655
uniprot id: B4SAA8
names: Similarity
messages: Belongs to the thioredoxin family.

324925:PPHA RS12900
gene id: 324925:PPHA_RS12900
uniprot id: B4SFV4
names: Similarity
messages: Belongs to the Fur family.

324925:PPHA RS09930
gene id: 324925:PPHA_RS09930
uniprot id: B4SCL0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

324925:PPHA RS09675
gene id: 324925:PPHA_RS09675
uniprot id: B4SC63
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NifD/NifK/NifE/NifN family.
messages: Binds 1 [8Fe-7S] cluster per heterodimer.
messages: Tetramer of two alpha and two beta chains. Forms complex with the iron protein (nitrogenase component 2).
messages: This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation.

324925:PPHA RS11785
gene id: 324925:PPHA_RS11785
uniprot id: B4SEQ0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

324925:PPHA RS09390
gene id: 324925:PPHA_RS09390
uniprot id: B4SC17
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

324925:PPHA RS10980
gene id: 324925:PPHA_RS10980
uniprot id: B4SDP8
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

324925:PPHA RS07510
gene id: 324925:PPHA_RS07510
uniprot id: B4SA68
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

324925:PPHA RS10230
gene id: 324925:PPHA_RS10230
uniprot id: B4SD14
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).

324925:PPHA RS11930
gene id: 324925:PPHA_RS11930
uniprot id: B4SES7
names: Similarity
messages: Belongs to the UPF0235 family.

324925:PPHA RS00025
gene id: 324925:PPHA_RS00025
uniprot id: B4SA98
names: Similarity
messages: In the N-terminal section; belongs to the zinc metallo-hydrolase group 3 family.

324925:PPHA RS05170
gene id: 324925:PPHA_RS05170
uniprot id: B4SFS2
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

324925:PPHA RS02240
gene id: 324925:PPHA_RS02240
uniprot id: B4SCU0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

324925:PPHA RS05910
gene id: 324925:PPHA_RS05910
uniprot id: B4SGP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

324925:PPHA RS08035
gene id: 324925:PPHA_RS08035
uniprot id: B4SAH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0761 family.
messages: Cell inner membrane

324925:PPHA RS10815
gene id: 324925:PPHA_RS10815
uniprot id: B4SDL8
names: Similarity
messages: Belongs to the calycin superfamily. Lipocalin family.

324925:PPHA RS02210
gene id: 324925:PPHA_RS02210
uniprot id: B4SCT4
names: Similarity
messages: Belongs to the phosphohexose mutase family.

324925:PPHA RS08135
gene id: 324925:PPHA_RS08135
uniprot id: B4SAJ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

324925:PPHA RS03535
gene id: 324925:PPHA_RS03535
uniprot id: B4SE20
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

324925:PPHA RS12130
gene id: 324925:PPHA_RS12130
uniprot id: B4SEW6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

324925:PPHA RS11370
gene id: 324925:PPHA_RS11370
uniprot id: B4SE76
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

324925:PPHA RS07680
gene id: 324925:PPHA_RS07680
uniprot id: B4SAB3
names: Similarity
messages: Belongs to the glycosyl hydrolase 65 family.

324925:PPHA RS14040
gene id: 324925:PPHA_RS14040
uniprot id: B4SH09
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

324925:PPHA RS10465
gene id: 324925:PPHA_RS10465
uniprot id: B4SD56
names: Similarity
messages: Belongs to the DEAD box helicase family.

324925:PPHA RS02780
gene id: 324925:PPHA_RS02780
uniprot id: B4SDD3
names: Similarity
messages: Belongs to the archaeal-type GPI family.

324925:PPHA RS03120
gene id: 324925:PPHA_RS03120
uniprot id: B4SDJ1
names: Subcellular Location Annotation
messages: Membrane

324925:PPHA RS14170
gene id: 324925:PPHA_RS14170
uniprot id: B4SH35
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

324925:PPHA RS11310
gene id: 324925:PPHA_RS11310
uniprot id: B4SE65
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 2 family.

324925:PPHA RS09920
gene id: 324925:PPHA_RS09920
uniprot id: B4SCK8
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

324925:PPHA RS07785
gene id: 324925:PPHA_RS07785
uniprot id: B4SAD0
names: Subcellular Location Annotation
messages: Membrane

324925:PPHA RS14080
gene id: 324925:PPHA_RS14080
uniprot id: B4SH17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Cell membrane
messages: Membrane

324925:PPHA RS06010
gene id: 324925:PPHA_RS06010
uniprot id: B4SGR4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

324925:PPHA RS06870
gene id: 324925:PPHA_RS06870
uniprot id: B4S9V0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

324925:PPHA RS07975
gene id: 324925:PPHA_RS07975
uniprot id: B4SAG4
names: Similarity
messages: Belongs to the glycosyltransferase 20 family.

324925:PPHA RS13430
gene id: 324925:PPHA_RS13430
uniprot id: B4SGE6
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

324925:PPHA RS11435
gene id: 324925:PPHA_RS11435
uniprot id: B4SE89
names: Subcellular Location Annotation
messages: Membrane

324925:PPHA RS11275
gene id: 324925:PPHA_RS11275
uniprot id: B4SE59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Membrane

324925:PPHA RS08810
gene id: 324925:PPHA_RS08810
uniprot id: B4SBF9
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

324925:PPHA RS01645
gene id: 324925:PPHA_RS01645
uniprot id: B4SC77
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BchN/ChlN family.
messages: Binds 1 [4Fe-4S] cluster per heterodimer. The cluster is bound at the heterodimer interface by residues from both subunits.
messages: Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein (BchN-BchB) is the catalytic component of the complex.
messages: Protochlorophyllide reductase is composed of three subunits; BchL, BchN and BchB. Forms a heterotetramer of two BchB and two BchN subunits.

324925:PPHA RS03465
gene id: 324925:PPHA_RS03465
uniprot id: B4SE07
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain.

324925:PPHA RS11005
gene id: 324925:PPHA_RS11005
uniprot id: B4SDQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

324925:PPHA RS09880
gene id: 324925:PPHA_RS09880
uniprot id: B4SCK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

324925:PPHA RS12105
gene id: 324925:PPHA_RS12105
uniprot id: B4SEW1
names: Similarity
messages: Belongs to the CRISPR-associated Csm3 family.

324925:PPHA RS14385
gene id: 324925:PPHA_RS14385
uniprot id: B4SHH0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell inner membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

324925:PPHA RS03655
gene id: 324925:PPHA_RS03655
uniprot id: B4SE44
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Monomer.

324925:PPHA RS06550
gene id: 324925:PPHA_RS06550
uniprot id: B4SHB4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

324925:PPHA RS10210
gene id: 324925:PPHA_RS10210
uniprot id: B4SCR3
names: Subcellular Location Annotation
messages: Membrane

324925:PPHA RS13160
gene id: 324925:PPHA_RS13160
uniprot id: B4SG04
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

324925:PPHA RS01985
gene id: 324925:PPHA_RS01985
uniprot id: B4SCE6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

324925:PPHA RS12330
gene id: 324925:PPHA_RS12330
uniprot id: B4SFA3
names: Similarity
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.

324925:PPHA RS06050
gene id: 324925:PPHA_RS06050
uniprot id: B4SGS2
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

324925:PPHA RS13385
gene id: 324925:PPHA_RS13385
uniprot id: B4SGD6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.

324925:PPHA RS03440
gene id: 324925:PPHA_RS03440
uniprot id: B4SE02
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. N-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

324925:PPHA RS12600
gene id: 324925:PPHA_RS12600
uniprot id: B4SFE4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

324925:PPHA RS03240
gene id: 324925:PPHA_RS03240
uniprot id: B4SDW3
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.

324925:PPHA RS07865
gene id: 324925:PPHA_RS07865
uniprot id: B4SAE5
names: Similarity
messages: Belongs to the HepT RNase toxin family.

324925:PPHA RS01615
gene id: 324925:PPHA_RS01615
uniprot id: B4SC71
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

324925:PPHA RS11765
gene id: 324925:PPHA_RS11765
uniprot id: B4SEP6
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

324925:PPHA RS03720
gene id: 324925:PPHA_RS03720
uniprot id: B4SEF5
names: Similarity
messages: Belongs to the phD/YefM antitoxin family.

324925:PPHA RS09665
gene id: 324925:PPHA_RS09665
uniprot id: B4SC61
names: Similarity
messages: Belongs to the P(II) protein family.

324925:PPHA RS02480
gene id: 324925:PPHA_RS02480
uniprot id: B4SCY6
names: Cofactor
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.

324925:PPHA RS07800
gene id: 324925:PPHA_RS07800
uniprot id: B4SAD3
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Homotetramer.

324925:PPHA RS07535
gene id: 324925:PPHA_RS07535
uniprot id: B4SA73
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

324925:PPHA RS01030
gene id: 324925:PPHA_RS01030
uniprot id: B4SBB6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

324925:PPHA RS01855
gene id: 324925:PPHA_RS01855
uniprot id: B4SCC0
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Feedback inhibited by histidine.

324925:PPHA RS11630
gene id: 324925:PPHA_RS11630
uniprot id: B4SEC6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

324925:PPHA RS13175
gene id: 324925:PPHA_RS13175
uniprot id: B4SG08
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

324925:PPHA RS06145
gene id: 324925:PPHA_RS06145
uniprot id: B4SGU1
names: Similarity
messages: Belongs to the heat shock protein 70 family.

324925:PPHA RS09010
gene id: 324925:PPHA_RS09010
uniprot id: B4SBJ5
names: Function
names: Similarity
messages: Belongs to the gas vesicle protein type A family.
messages: Gas vesicles are small, hollow, gas filled protein structures that are found in several microbial planktonic microorganisms. They allow the positioning of the organism at the favorable depth for growth.

324925:PPHA RS11790
gene id: 324925:PPHA_RS11790
uniprot id: B4SEQ1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

324925:PPHA RS08325
gene id: 324925:PPHA_RS08325
uniprot id: B4SAX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

324925:PPHA RS14015
gene id: 324925:PPHA_RS14015
uniprot id: B4SH04
names: Subcellular Location Annotation
messages: Membrane

324925:PPHA RS01025
gene id: 324925:PPHA_RS01025
uniprot id: B4SBB5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

324925:PPHA RS14640
gene id: 324925:PPHA_RS14640
uniprot id: B4SAX5
names: Similarity
messages: Belongs to the alkaline phosphatase family.

324925:PPHA RS02115
gene id: 324925:PPHA_RS02115
uniprot id: B4SCH0
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

324925:PPHA RS01675
gene id: 324925:PPHA_RS01675
uniprot id: B4SC83
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

324925:PPHA RS13340
gene id: 324925:PPHA_RS13340
uniprot id: B4SGC7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a, b, b' and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

324925:PPHA RS01220
gene id: 324925:PPHA_RS01220
uniprot id: B4SBQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic sulfate-binding protein family.
messages: Periplasm

324925:PPHA RS10705
gene id: 324925:PPHA_RS10705
uniprot id: B4SDA3
names: Similarity
messages: Belongs to the Pal lipoprotein family.

324925:PPHA RS00450
gene id: 324925:PPHA_RS00450
uniprot id: B4SAS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

324925:PPHA RS00525
gene id: 324925:PPHA_RS00525
uniprot id: B4SAT8
names: Similarity
messages: Belongs to the Fur family.

324925:PPHA RS01045
gene id: 324925:PPHA_RS01045
uniprot id: B4SBC0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homotetramer.

324925:PPHA RS13195
gene id: 324925:PPHA_RS13195
uniprot id: B4SG12
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

324925:PPHA RS05175
gene id: 324925:PPHA_RS05175
uniprot id: B4SFS3
names: Cofactor
names: Similarity
messages: Belongs to the iron-containing alcohol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.

324925:PPHA RS11405
gene id: 324925:PPHA_RS11405
uniprot id: B4SE82
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

324925:PPHA RS05040
gene id: 324925:PPHA_RS05040
uniprot id: B4SFP6
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

324925:PPHA RS11795
gene id: 324925:PPHA_RS11795
uniprot id: B4SEQ2
names: Similarity
messages: Belongs to the BshC family.

324925:PPHA RS04560
gene id: 324925:PPHA_RS04560
uniprot id: B4SF60
names: Similarity
messages: Belongs to the acylphosphatase family.

324925:PPHA RS08605
gene id: 324925:PPHA_RS08605
uniprot id: B4SB26
names: Function
names: Similarity
messages: Belongs to the PemK/MazF family.
messages: Toxic component of a type II toxin-antitoxin (TA) system.

324925:PPHA RS04250
gene id: 324925:PPHA_RS04250
uniprot id: B4SEZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate.
messages: Cytoplasm

324925:PPHA RS02100
gene id: 324925:PPHA_RS02100
uniprot id: B4SCG7
names: Subcellular Location Annotation
messages: Membrane

324925:PPHA RS03150
gene id: 324925:PPHA_RS03150
uniprot id: B4SDJ7
names: Similarity
messages: Belongs to the glycosyltransferase 41 family. O-GlcNAc transferase subfamily.

324925:PPHA RS04335
gene id: 324925:PPHA_RS04335
uniprot id: B4SF17
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

324925:PPHA RS07965
gene id: 324925:PPHA_RS07965
uniprot id: B4SAG2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

324925:PPHA RS12610
gene id: 324925:PPHA_RS12610
uniprot id: B4SFE6
names: Similarity
messages: Belongs to the peptidase M16 family.

324925:PPHA RS06800
gene id: 324925:PPHA_RS06800
uniprot id: B4S9T6
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.

324925:PPHA RS10335
gene id: 324925:PPHA_RS10335
uniprot id: B4SD35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

324925:PPHA RS07810
gene id: 324925:PPHA_RS07810
uniprot id: B4SAD5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

324925:PPHA RS12930
gene id: 324925:PPHA_RS12930
uniprot id: B4SFW0
names: Similarity
messages: Belongs to the FGGY kinase family.

324925:PPHA RS14750
gene id: 324925:PPHA_RS14750
uniprot id: B4SEW2
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated Csm2 family.
messages: This subunit may be involved in monitoring complementarity of crRNA and target RNA.

324925:PPHA RS13005
gene id: 324925:PPHA_RS13005
uniprot id: B4SFX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

324925:PPHA RS02625
gene id: 324925:PPHA_RS02625
uniprot id: B4SDB0
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

324925:PPHA RS11255
gene id: 324925:PPHA_RS11255
uniprot id: B4SE55
names: Caution
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

324925:PPHA RS01000
gene id: 324925:PPHA_RS01000
uniprot id: B4SBB0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

324925:PPHA RS05830
gene id: 324925:PPHA_RS05830
uniprot id: B4SGN1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterotetramer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits of ACCase subunit beta/alpha.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the AccA family.
messages: In the N-terminal section; belongs to the AccD/PCCB family.

324925:PPHA RS12695
gene id: 324925:PPHA_RS12695
uniprot id: B4SFG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

324925:PPHA RS13800
gene id: 324925:PPHA_RS13800
uniprot id: B4SGW3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell inner membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

324925:PPHA RS09170
gene id: 324925:PPHA_RS09170
uniprot id: B4SBX7
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

324925:PPHA RS11865
gene id: 324925:PPHA_RS11865
uniprot id: B4SER4
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

324925:PPHA RS01845
gene id: 324925:PPHA_RS01845
uniprot id: B4SCB8
names: Subcellular Location Annotation
messages: Membrane

324925:PPHA RS06620
gene id: 324925:PPHA_RS06620
uniprot id: B4SHC7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

324925:PPHA RS03360
gene id: 324925:PPHA_RS03360
uniprot id: B4SDY6
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

324925:PPHA RS09840
gene id: 324925:PPHA_RS09840
uniprot id: B4SCJ3
names: Similarity
messages: Belongs to the ModE family.

324925:PPHA RS08685
gene id: 324925:PPHA_RS08685
uniprot id: B4SBD4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

324925:PPHA RS11400
gene id: 324925:PPHA_RS11400
uniprot id: B4SE81
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell inner membrane

324925:PPHA RS09350
gene id: 324925:PPHA_RS09350
uniprot id: B4SC11
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

324925:PPHA RS08090
gene id: 324925:PPHA_RS08090
uniprot id: B4SAI5
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

324925:PPHA RS11010
gene id: 324925:PPHA_RS11010
uniprot id: B4SDQ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
messages: Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
messages: Homodimer.

324925:PPHA RS08060
gene id: 324925:PPHA_RS08060
uniprot id: B4SAH9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

324925:PPHA RS07390
gene id: 324925:PPHA_RS07390
uniprot id: B4SA44
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates guanosine-37 in various tRNAs.

324925:PPHA RS05990
gene id: 324925:PPHA_RS05990
uniprot id: B4SGR0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Monomer.

324925:PPHA RS13580
gene id: 324925:PPHA_RS13580
uniprot id: B4SGH2
names: Similarity
messages: Belongs to the arsA ATPase family.

324925:PPHA RS06290
gene id: 324925:PPHA_RS06290
uniprot id: B4SH62
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.

324925:PPHA RS11325
gene id: 324925:PPHA_RS11325
uniprot id: B4SE68
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

324925:PPHA RS12665
gene id: 324925:PPHA_RS12665
uniprot id: B4SFF7
names: Similarity
messages: Belongs to the arsA ATPase family.

324925:PPHA RS05405
gene id: 324925:PPHA_RS05405
uniprot id: B4SG59
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

324925:PPHA RS06790
gene id: 324925:PPHA_RS06790
uniprot id: B4S9T4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

324925:PPHA RS06610
gene id: 324925:PPHA_RS06610
uniprot id: B4SHC5
names: Subcellular Location Annotation
messages: Membrane

324925:PPHA RS02010
gene id: 324925:PPHA_RS02010
uniprot id: B4SCF0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

324925:PPHA RS13355
gene id: 324925:PPHA_RS13355
uniprot id: B4SGD0
names: Domain
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

324925:PPHA RS02450
gene id: 324925:PPHA_RS02450
uniprot id: B4SCY0
names: Similarity
messages: Belongs to the ferrochelatase family.

324925:PPHA RS10765
gene id: 324925:PPHA_RS10765
uniprot id: B4SDK7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.

324925:PPHA RS09190
gene id: 324925:PPHA_RS09190
uniprot id: B4SBY1
names: Similarity
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.

324925:PPHA RS09905
gene id: 324925:PPHA_RS09905
uniprot id: B4SCK5
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

324925:PPHA RS14145
gene id: 324925:PPHA_RS14145
uniprot id: B4SH30
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 3B subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

324925:PPHA RS06005
gene id: 324925:PPHA_RS06005
uniprot id: B4SGR3
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

324925:PPHA RS11030
gene id: 324925:PPHA_RS11030
uniprot id: B4SDQ8
names: Similarity
messages: Belongs to the HipA Ser/Thr kinase family.

324925:PPHA RS13500
gene id: 324925:PPHA_RS13500
uniprot id: B4SGF8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

324925:PPHA RS03790
gene id: 324925:PPHA_RS03790
uniprot id: B4SEH0
names: Subcellular Location Annotation
messages: Membrane

324925:PPHA RS13300
gene id: 324925:PPHA_RS13300
uniprot id: B4SGC0
names: Subcellular Location Annotation
messages: Membrane

324925:PPHA RS14325
gene id: 324925:PPHA_RS14325
uniprot id: B4SHF9
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

324925:PPHA RS01525
gene id: 324925:PPHA_RS01525
uniprot id: B4SBV8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

324925:PPHA RS02830
gene id: 324925:PPHA_RS02830
uniprot id: B4SDE3
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. Fucose synthase subfamily.
messages: Catalyzes the two-step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.

324925:PPHA RS12840
gene id: 324925:PPHA_RS12840
uniprot id: B4SFU3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
messages: Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.
messages: Cytoplasm

324925:PPHA RS13345
gene id: 324925:PPHA_RS13345
uniprot id: B4SGC8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

324925:PPHA RS03290
gene id: 324925:PPHA_RS03290
uniprot id: B4SDX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

324925:PPHA RS13795
gene id: 324925:PPHA_RS13795
uniprot id: B4SGW2
names: Similarity
messages: Belongs to the UPF0166 family.

324925:PPHA RS08680
gene id: 324925:PPHA_RS08680
uniprot id: B4SBD3
names: Cofactor
names: PTM
names: Subcellular Location Annotation
messages: Binds 2 heme groups per subunit.
messages: Binds 2 heme groups.
messages: Periplasm

324925:PPHA RS03615
gene id: 324925:PPHA_RS03615
uniprot id: B4SE36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

324925:PPHA RS14165
gene id: 324925:PPHA_RS14165
uniprot id: B4SH34
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

324925:PPHA RS02435
gene id: 324925:PPHA_RS02435
uniprot id: B4SCX7
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).

324925:PPHA RS02930
gene id: 324925:PPHA_RS02930
uniprot id: B4SDG0
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.
messages: Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

324925:PPHA RS02505
gene id: 324925:PPHA_RS02505
uniprot id: B4SCZ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.

324925:PPHA RS10910
gene id: 324925:PPHA_RS10910
uniprot id: B4SDN4
names: Subcellular Location Annotation
messages: Membrane

324925:PPHA RS01350
gene id: 324925:PPHA_RS01350
uniprot id: B4SBS7
names: Similarity
messages: Belongs to the HipA Ser/Thr kinase family.

324925:PPHA RS03605
gene id: 324925:PPHA_RS03605
uniprot id: B4SE34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

324925:PPHA RS10965
gene id: 324925:PPHA_RS10965
uniprot id: B4SDP5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

324925:PPHA RS02175
gene id: 324925:PPHA_RS02175
uniprot id: B4SCS7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

324925:PPHA RS11780
gene id: 324925:PPHA_RS11780
uniprot id: B4SEP9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

324925:PPHA RS00660
gene id: 324925:PPHA_RS00660
uniprot id: B4SB53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

324925:PPHA RS11320
gene id: 324925:PPHA_RS11320
uniprot id: B4SE67
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

324925:PPHA RS12810
gene id: 324925:PPHA_RS12810
uniprot id: B4SFT7
names: Subcellular Location Annotation
messages: Membrane

324925:PPHA RS06795
gene id: 324925:PPHA_RS06795
uniprot id: B4S9T5
names: Similarity
messages: Belongs to the peptidase S24 family.

324925:PPHA RS04890
gene id: 324925:PPHA_RS04890
uniprot id: B4SFL6
names: Similarity
messages: Belongs to the DinB family.

324925:PPHA RS07385
gene id: 324925:PPHA_RS07385
uniprot id: B4SA43
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

324925:PPHA RS00010
gene id: 324925:PPHA_RS00010
uniprot id: B4SA95
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

324925:PPHA RS05260
gene id: 324925:PPHA_RS05260
uniprot id: B4SG33
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

324925:PPHA RS12615
gene id: 324925:PPHA_RS12615
uniprot id: B4SFE7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

324925:PPHA RS04270
gene id: 324925:PPHA_RS04270
uniprot id: B4SF03
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

324925:PPHA RS00835
gene id: 324925:PPHA_RS00835
uniprot id: B4SB83
names: Similarity
messages: Belongs to the UPF0175 family.

324925:PPHA RS13200
gene id: 324925:PPHA_RS13200
uniprot id: B4SG13
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

324925:PPHA RS13325
gene id: 324925:PPHA_RS13325
uniprot id: B4SGC4
names: Similarity
messages: Belongs to the CinA family.

324925:PPHA RS03300
gene id: 324925:PPHA_RS03300
uniprot id: B4SDX5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

324925:PPHA RS08925
gene id: 324925:PPHA_RS08925
uniprot id: B4SBH9
names: Function
names: Subcellular Location Annotation
messages: May play a structural or regulatory role in gas vesicle synthesis.
messages: Vesicle
messages: gas vesicle

324925:PPHA RS03970
gene id: 324925:PPHA_RS03970
uniprot id: B4SEK3
names: Subcellular Location Annotation
messages: Membrane

324925:PPHA RS05460
gene id: 324925:PPHA_RS05460
uniprot id: B4SG70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

324925:PPHA RS02285
gene id: 324925:PPHA_RS02285
uniprot id: B4SCU9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. MrdB/RodA subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell wall elongation.

324925:PPHA RS04555
gene id: 324925:PPHA_RS04555
uniprot id: B4SF59
names: Similarity
messages: Belongs to the YjdM family.

324925:PPHA RS06440
gene id: 324925:PPHA_RS06440
uniprot id: B4SH92
names: Function
names: Similarity
messages: Belongs to the CobT family.
messages: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).

324925:PPHA RS07125
gene id: 324925:PPHA_RS07125
uniprot id: B4S9Z5
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild-type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity.
messages: Belongs to the RecC family.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding.

324925:PPHA RS13400
gene id: 324925:PPHA_RS13400
uniprot id: B4SGD9
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.

324925:PPHA RS13770
gene id: 324925:PPHA_RS13770
uniprot id: B4SGV7
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

324925:PPHA RS06720
gene id: 324925:PPHA_RS06720
uniprot id: B4S9S0
names: Similarity
messages: Belongs to the BMP lipoprotein family.

324925:PPHA RS14225
gene id: 324925:PPHA_RS14225
uniprot id: B4SH45
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

324925:PPHA RS05045
gene id: 324925:PPHA_RS05045
uniprot id: B4SFP7
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

324925:PPHA RS03650
gene id: 324925:PPHA_RS03650
uniprot id: B4SE43
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

324925:PPHA RS07570
gene id: 324925:PPHA_RS07570
uniprot id: B4SA80
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

324925:PPHA RS05075
gene id: 324925:PPHA_RS05075
uniprot id: B4SFQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MenA family. Type 1 subfamily.
messages: Cell inner membrane
messages: Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).
messages: Membrane

324925:PPHA RS08770
gene id: 324925:PPHA_RS08770
uniprot id: B4SBF1
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

324925:PPHA RS09195
gene id: 324925:PPHA_RS09195
uniprot id: B4SBY2
names: Similarity
names: Subunit
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family.
messages: Heterodimer of a large and a small subunit.

324925:PPHA RS07540
gene id: 324925:PPHA_RS07540
uniprot id: B4SA74
names: Similarity
messages: Belongs to the arsA ATPase family.

324925:PPHA RS00480
gene id: 324925:PPHA_RS00480
uniprot id: B4SAT3
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

324925:PPHA RS10660
gene id: 324925:PPHA_RS10660
uniprot id: B4SD94
names: Similarity
messages: Belongs to the AlaDH/PNT family.

324925:PPHA RS12545
gene id: 324925:PPHA_RS12545
uniprot id: B4SFD3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Monomer.

324925:PPHA RS01310
gene id: 324925:PPHA_RS01310
uniprot id: B4SBS0
names: Subcellular Location Annotation
messages: Membrane

324925:PPHA RS13955
gene id: 324925:PPHA_RS13955
uniprot id: B4SGZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.

324925:PPHA RS13205
gene id: 324925:PPHA_RS13205
uniprot id: B4SG14
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

324925:PPHA RS10730
gene id: 324925:PPHA_RS10730
uniprot id: B4SDJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

324925:PPHA RS03975
gene id: 324925:PPHA_RS03975
uniprot id: B4SEK4
names: Subcellular Location Annotation
messages: Membrane

324925:PPHA RS09210
gene id: 324925:PPHA_RS09210
uniprot id: B4SBY5
names: Subcellular Location Annotation
messages: Membrane

324925:PPHA RS02530
gene id: 324925:PPHA_RS02530
uniprot id: B4SCZ6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

324925:PPHA RS11415
gene id: 324925:PPHA_RS11415
uniprot id: B4SE85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

324925:PPHA RS11490
gene id: 324925:PPHA_RS11490
uniprot id: B4SEA0
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

324925:PPHA RS06080
gene id: 324925:PPHA_RS06080
uniprot id: B4SGS8
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

324925:PPHA RS01750
gene id: 324925:PPHA_RS01750
uniprot id: B4SC98
names: Subcellular Location Annotation
messages: Membrane

324925:PPHA RS01010
gene id: 324925:PPHA_RS01010
uniprot id: B4SBB2
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

324925:PPHA RS10270
gene id: 324925:PPHA_RS10270
uniprot id: B4SD22
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Binds 1 copper ion per subunit, denoted as copper B.
messages: Binds 2 heme groups per subunit, denoted as high- and low-spin.
messages: Membrane

324925:PPHA RS04245
gene id: 324925:PPHA_RS04245
uniprot id: B4SEZ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
messages: Homodimer.

324925:PPHA RS02260
gene id: 324925:PPHA_RS02260
uniprot id: B4SCU4
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS1 family.
messages: Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.

324925:PPHA RS08970
gene id: 324925:PPHA_RS08970
uniprot id: B4SBI8
names: Similarity
messages: Belongs to the AAA ATPase family.

324925:PPHA RS00135
gene id: 324925:PPHA_RS00135
uniprot id: B4SAL8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm
messages: Homodimer.

324925:PPHA RS08100
gene id: 324925:PPHA_RS08100
uniprot id: B4SAI7
names: Subcellular Location Annotation
messages: Membrane

324925:PPHA RS10400
gene id: 324925:PPHA_RS10400
uniprot id: B4SD43
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

324925:PPHA RS05810
gene id: 324925:PPHA_RS05810
uniprot id: B4SGM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

324925:PPHA RS05965
gene id: 324925:PPHA_RS05965
uniprot id: B4SGQ6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.

324925:PPHA RS03265
gene id: 324925:PPHA_RS03265
uniprot id: B4SDW8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxC family.
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

324925:PPHA RS00895
gene id: 324925:PPHA_RS00895
uniprot id: B4SB92
names: Similarity
messages: Belongs to the IF-3 family.

324925:PPHA RS13395
gene id: 324925:PPHA_RS13395
uniprot id: B4SGD8
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

324925:PPHA RS12730
gene id: 324925:PPHA_RS12730
uniprot id: B4SFG9
names: Similarity
messages: Belongs to the YoeB family.

324925:PPHA RS14370
gene id: 324925:PPHA_RS14370
uniprot id: B4SHG7
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

324925:PPHA RS02320
gene id: 324925:PPHA_RS02320
uniprot id: B4SCV6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Monomer.

324925:PPHA RS07830
gene id: 324925:PPHA_RS07830
uniprot id: B4SAD8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

324925:PPHA RS08575
gene id: 324925:PPHA_RS08575
uniprot id: B4SB20
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

324925:PPHA RS04265
gene id: 324925:PPHA_RS04265
uniprot id: B4SF02
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

324925:PPHA RS04900
gene id: 324925:PPHA_RS04900
uniprot id: B4SFL8
names: Function
names: Similarity
messages: Belongs to the RecD family. RecD-like subfamily.
messages: DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity.

324925:PPHA RS07550
gene id: 324925:PPHA_RS07550
uniprot id: B4SA76
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.

324925:PPHA RS00595
gene id: 324925:PPHA_RS00595
uniprot id: B4SB44
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

324925:PPHA RS04730
gene id: 324925:PPHA_RS04730
uniprot id: B4SFI6
names: Similarity
messages: Belongs to the glutamate synthase family.

324925:PPHA RS02190
gene id: 324925:PPHA_RS02190
uniprot id: B4SCT0
names: Subcellular Location Annotation
messages: Membrane

324925:PPHA RS00520
gene id: 324925:PPHA_RS00520
uniprot id: B4SAT7
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the peroxidase family. Peroxidase/catalase subfamily.
messages: Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.
messages: Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.
messages: Homodimer or homotetramer.

324925:PPHA RS11920
gene id: 324925:PPHA_RS11920
uniprot id: B4SES5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

324925:PPHA RS00385
gene id: 324925:PPHA_RS00385
uniprot id: B4SAR5
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

324925:PPHA RS10685
gene id: 324925:PPHA_RS10685
uniprot id: B4SD99
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

324925:PPHA RS04190
gene id: 324925:PPHA_RS04190
uniprot id: B4SEZ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

324925:PPHA RS06905
gene id: 324925:PPHA_RS06905
uniprot id: B4S9V8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell inner membrane

324925:PPHA RS06045
gene id: 324925:PPHA_RS06045
uniprot id: B4SGS1
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

324925:PPHA RS05495
gene id: 324925:PPHA_RS05495
uniprot id: B4SG76
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

324925:PPHA RS05530
gene id: 324925:PPHA_RS05530
uniprot id: B4SG83
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

324925:PPHA RS13265
gene id: 324925:PPHA_RS13265
uniprot id: B4SGB3
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.

324925:PPHA RS04725
gene id: 324925:PPHA_RS04725
uniprot id: B4SFI5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

324925:PPHA RS04995
gene id: 324925:PPHA_RS04995
uniprot id: B4SFN7
names: Subcellular Location Annotation
messages: Membrane

324925:PPHA RS03780
gene id: 324925:PPHA_RS03780
uniprot id: B4SEG8
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

324925:PPHA RS06930
gene id: 324925:PPHA_RS06930
uniprot id: B4S9W3
names: Similarity
messages: Belongs to the HepT RNase toxin family.

324925:PPHA RS09720
gene id: 324925:PPHA_RS09720
uniprot id: B4SCH3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane

324925:PPHA RS03560
gene id: 324925:PPHA_RS03560
uniprot id: B4SE25
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate.
messages: Cytoplasm

324925:PPHA RS07170
gene id: 324925:PPHA_RS07170
uniprot id: B4SA04
names: Similarity
messages: Belongs to the phD/YefM antitoxin family.

324925:PPHA RS06680
gene id: 324925:PPHA_RS06680
uniprot id: B4SHE0
names: Similarity
messages: Belongs to the UPF0251 family.

324925:PPHA RS09690
gene id: 324925:PPHA_RS09690
uniprot id: B4SC66
names: Similarity
messages: Belongs to the radical SAM superfamily. NifB family.

324925:PPHA RS12715
gene id: 324925:PPHA_RS12715
uniprot id: B4SFG6
names: Similarity
messages: Belongs to the Mg-chelatase subunit H family.

324925:PPHA RS02575
gene id: 324925:PPHA_RS02575
uniprot id: B4SD05
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

324925:PPHA RS14290
gene id: 324925:PPHA_RS14290
uniprot id: B4SHF2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

324925:PPHA RS05835
gene id: 324925:PPHA_RS05835
uniprot id: B4SGN2
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

324925:PPHA RS01650
gene id: 324925:PPHA_RS01650
uniprot id: B4SC78
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ChlB/BchB/BchZ family.
messages: Binds 1 [4Fe-4S] cluster per heterodimer. The cluster is bound at the heterodimer interface by residues from both subunits.
messages: Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein (BchN-BchB) is the catalytic component of the complex.
messages: Protochlorophyllide reductase is composed of three subunits; BchL, BchN and BchB. Forms a heterotetramer of two BchB and two BchN subunits.

324925:PPHA RS00065
gene id: 324925:PPHA_RS00065
uniprot id: B4SAK4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

324925:PPHA RS01605
gene id: 324925:PPHA_RS01605
uniprot id: B4SBX4
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

324925:PPHA RS00035
gene id: 324925:PPHA_RS00035
uniprot id: B4SAA0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

324925:PPHA RS03215
gene id: 324925:PPHA_RS03215
uniprot id: B4SDV8
names: Similarity
messages: Belongs to the TrpC family.

324925:PPHA RS01205
gene id: 324925:PPHA_RS01205
uniprot id: B4SBP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the kinesin light chain family.
messages: cytoskeleton

324925:PPHA RS12085
gene id: 324925:PPHA_RS12085
uniprot id: B4SEV7
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated protein Cas6/Cse3/CasE family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).

324925:PPHA RS13660
gene id: 324925:PPHA_RS13660
uniprot id: B4SGI8
names: Function
names: Similarity
messages: Belongs to the RlpA family.
messages: Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.

324925:PPHA RS09475
gene id: 324925:PPHA_RS09475
uniprot id: B4SC30
names: Similarity
messages: Belongs to the XFP family.

324925:PPHA RS02250
gene id: 324925:PPHA_RS02250
uniprot id: B4SCU2
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

324925:PPHA RS14185
gene id: 324925:PPHA_RS14185
uniprot id: B4SH37
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase delta chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

324925:PPHA RS01265
gene id: 324925:PPHA_RS01265
uniprot id: B4SBR1
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

324925:PPHA RS12620
gene id: 324925:PPHA_RS12620
uniprot id: B4SFE8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

324925:PPHA RS09345
gene id: 324925:PPHA_RS09345
uniprot id: B4SC10
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

324925:PPHA RS01720
gene id: 324925:PPHA_RS01720
uniprot id: B4SC92
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

324925:PPHA RS10360
gene id: 324925:PPHA_RS10360
uniprot id: B4SD39
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

324925:PPHA RS11520
gene id: 324925:PPHA_RS11520
uniprot id: B4SEA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

324925:PPHA RS11655
gene id: 324925:PPHA_RS11655
uniprot id: B4SED1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

324925:PPHA RS13350
gene id: 324925:PPHA_RS13350
uniprot id: B4SGC9
names: Similarity
messages: Belongs to the threonine synthase family.

324925:PPHA RS09250
gene id: 324925:PPHA_RS09250
uniprot id: B4SBZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

324925:PPHA RS02440
gene id: 324925:PPHA_RS02440
uniprot id: B4SCX8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

324925:PPHA RS02560
gene id: 324925:PPHA_RS02560
uniprot id: B4SD02
names: Subcellular Location Annotation
messages: Membrane

324925:PPHA RS13185
gene id: 324925:PPHA_RS13185
uniprot id: B4SG10
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

324925:PPHA RS05420
gene id: 324925:PPHA_RS05420
uniprot id: B4SG62
names: Subcellular Location Annotation
messages: Membrane

324925:PPHA RS01595
gene id: 324925:PPHA_RS01595
uniprot id: B4SBX2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

324925:PPHA RS07960
gene id: 324925:PPHA_RS07960
uniprot id: B4SAG1
names: Subcellular Location Annotation
messages: Membrane

324925:PPHA RS05980
gene id: 324925:PPHA_RS05980
uniprot id: B4SGQ8
names: Similarity
messages: Belongs to the CFA/CMAS family.

324925:PPHA RS08820
gene id: 324925:PPHA_RS08820
uniprot id: B4SBG1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

324925:PPHA RS01535
gene id: 324925:PPHA_RS01535
uniprot id: B4SBW0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

324925:PPHA RS13655
gene id: 324925:PPHA_RS13655
uniprot id: B4SGI7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
messages: Cell inner membrane
messages: Membrane
messages: Transport of potassium into the cell.

324925:PPHA RS09970
gene id: 324925:PPHA_RS09970
uniprot id: B4SCL8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

324925:PPHA RS02850
gene id: 324925:PPHA_RS02850
uniprot id: B4SDE7
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

324925:PPHA RS06745
gene id: 324925:PPHA_RS06745
uniprot id: B4S9S5
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

324925:PPHA RS13170
gene id: 324925:PPHA_RS13170
uniprot id: B4SG07
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

324925:PPHA RS09160
gene id: 324925:PPHA_RS09160
uniprot id: B4SBM6
names: Similarity
messages: Belongs to the thioredoxin family.

324925:PPHA RS01590
gene id: 324925:PPHA_RS01590
uniprot id: B4SBX1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

324925:PPHA RS02300
gene id: 324925:PPHA_RS02300
uniprot id: B4SCV2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

324925:PPHA RS09335
gene id: 324925:PPHA_RS09335
uniprot id: B4SC08
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the peroxiredoxin family. Tpx subfamily.
messages: Homodimer.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this atypical 2-Cys peroxiredoxin, C(R) is present in the same subunit to form an intramolecular disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

324925:PPHA RS06555
gene id: 324925:PPHA_RS06555
uniprot id: B4SHB5
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

324925:PPHA RS02485
gene id: 324925:PPHA_RS02485
uniprot id: B4SCY7
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

324925:PPHA RS02040
gene id: 324925:PPHA_RS02040
uniprot id: B4SCF6
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

324925:PPHA RS01545
gene id: 324925:PPHA_RS01545
uniprot id: B4SBW2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

324925:PPHA RS01285
gene id: 324925:PPHA_RS01285
uniprot id: B4SBR5
names: Subcellular Location Annotation
messages: Cytoplasm

324925:PPHA RS01795
gene id: 324925:PPHA_RS01795
uniprot id: B4SCA7
names: Subcellular Location Annotation
messages: Membrane

324925:PPHA RS07305
gene id: 324925:PPHA_RS07305
uniprot id: B4SA29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

324925:PPHA RS07970
gene id: 324925:PPHA_RS07970
uniprot id: B4SAG3
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

324925:PPHA RS06300
gene id: 324925:PPHA_RS06300
uniprot id: B4SH64
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

324925:PPHA RS13210
gene id: 324925:PPHA_RS13210
uniprot id: B4SG15
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

324925:PPHA RS07450
gene id: 324925:PPHA_RS07450
uniprot id: B4SA56
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

324925:PPHA RS03295
gene id: 324925:PPHA_RS03295
uniprot id: B4SDX4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

324925:PPHA RS12825
gene id: 324925:PPHA_RS12825
uniprot id: B4SFU0
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

324925:PPHA RS09480
gene id: 324925:PPHA_RS09480
uniprot id: B4SC31
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mg(2+). Can also accept Mn(2+).

324925:PPHA RS02885
gene id: 324925:PPHA_RS02885
uniprot id: B4SDF4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

324925:PPHA RS13995
gene id: 324925:PPHA_RS13995
uniprot id: B4SH00
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

324925:PPHA RS11270
gene id: 324925:PPHA_RS11270
uniprot id: B4SE58
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AP endonuclease 2 family.
messages: Binds 3 Zn(2+) ions.
messages: Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.

324925:PPHA RS10170
gene id: 324925:PPHA_RS10170
uniprot id: B4SCQ3
names: Similarity
messages: Belongs to the carbamoyltransferase HypF family.

324925:PPHA RS01150
gene id: 324925:PPHA_RS01150
uniprot id: B4SBN7
names: Similarity
messages: Belongs to the Pal lipoprotein family.

324925:PPHA RS08830
gene id: 324925:PPHA_RS08830
uniprot id: B4SBG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

324925:PPHA RS01955
gene id: 324925:PPHA_RS01955
uniprot id: B4SCE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

324925:PPHA RS06445
gene id: 324925:PPHA_RS06445
uniprot id: B4SH93
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell inner membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.

324925:PPHA RS08895
gene id: 324925:PPHA_RS08895
uniprot id: B4SBH3
names: Function
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family.
messages: Involved in bacteriochlorophyll biosynthesis; introduces a magnesium ion into protoporphyrin IX to yield Mg-protoporphyrin IX.

324925:PPHA RS09355
gene id: 324925:PPHA_RS09355
uniprot id: B4SC12
names: Function
names: Similarity
names: Subunit
messages: Associates with stalled 50S ribosomal subunits.
messages: Belongs to the NEMF family.
messages: Part of the ribosome quality control system (RQC). Recruits Ala-charged tRNA and directs the elongation of stalled nascent chains on 50S ribosomal subunits, leading to non-templated C-terminal Ala extensions (Ala tail). The Ala tail promotes nascent chain degradation. May add between 1 and at least 8 Ala residues. Binds to stalled 50S ribosomal subunits.

324925:PPHA RS10235
gene id: 324925:PPHA_RS10235
uniprot id: B4SD15
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell inner membrane
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

324925:PPHA RS06850
gene id: 324925:PPHA_RS06850
uniprot id: B4S9U6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

324925:PPHA RS11635
gene id: 324925:PPHA_RS11635
uniprot id: B4SEC7
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

324925:PPHA RS13735
gene id: 324925:PPHA_RS13735
uniprot id: B4SGK2
names: Similarity
messages: Belongs to the DNA/RNA non-specific endonuclease family.

324925:PPHA RS09025
gene id: 324925:PPHA_RS09025
uniprot id: B4SBJ5
names: Function
names: Similarity
messages: Belongs to the gas vesicle protein type A family.
messages: Gas vesicles are small, hollow, gas filled protein structures that are found in several microbial planktonic microorganisms. They allow the positioning of the organism at the favorable depth for growth.

324925:PPHA RS02280
gene id: 324925:PPHA_RS02280
uniprot id: B4SCU8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell inner membrane
messages: Cytoplasm
messages: Monomer.

324925:PPHA RS08155
gene id: 324925:PPHA_RS08155
uniprot id: B4SAJ8
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

324925:PPHA RS01715
gene id: 324925:PPHA_RS01715
uniprot id: B4SC91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

324925:PPHA RS12500
gene id: 324925:PPHA_RS12500
uniprot id: B4SFC5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BChl C/E-binding protein family.
messages: Component of the photosynthetic apparatus.
messages: chlorosome envelope

324925:PPHA RS03455
gene id: 324925:PPHA_RS03455
uniprot id: B4SE05
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

324925:PPHA RS03270
gene id: 324925:PPHA_RS03270
uniprot id: B4SDW9
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

324925:PPHA RS07400
gene id: 324925:PPHA_RS07400
uniprot id: B4SA46
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

324925:PPHA RS08730
gene id: 324925:PPHA_RS08730
uniprot id: B4SBE3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

324925:PPHA RS11290
gene id: 324925:PPHA_RS11290
uniprot id: B4SE61
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

324925:PPHA RS11665
gene id: 324925:PPHA_RS11665
uniprot id: B4SED3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Homohexamer. Forms a ring that surrounds DNA.
messages: Membrane

324925:PPHA RS01655
gene id: 324925:PPHA_RS01655
uniprot id: B4SC79
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NifH/BchL/ChlL family.
messages: Binds 1 [4Fe-4S] cluster per dimer.
messages: Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The L component serves as a unique electron donor to the NB-component of the complex, and binds Mg-ATP.
messages: Homodimer. Protochlorophyllide reductase is composed of three subunits; BchL, BchN and BchB.

324925:PPHA RS10260
gene id: 324925:PPHA_RS10260
uniprot id: B4SD20
names: Function
names: Similarity
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.

324925:PPHA RS08960
gene id: 324925:PPHA_RS08960
uniprot id: B4SBI6
names: Function
names: Subcellular Location Annotation
messages: May play a structural or regulatory role in gas vesicle synthesis.
messages: Vesicle
messages: gas vesicle

324925:PPHA RS07815
gene id: 324925:PPHA_RS07815
uniprot id: B4SAD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

324925:PPHA RS00120
gene id: 324925:PPHA_RS00120
uniprot id: B4SAL5
names: Similarity
messages: Belongs to the peptidase S41A family.

324925:PPHA RS08105
gene id: 324925:PPHA_RS08105
uniprot id: B4SAI8
names: Subcellular Location Annotation
messages: Membrane

324925:PPHA RS01640
gene id: 324925:PPHA_RS01640
uniprot id: B4SC76
names: Similarity
messages: Belongs to the UPF0045 family.

324925:PPHA RS12820
gene id: 324925:PPHA_RS12820
uniprot id: B4SFT9
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.

324925:PPHA RS00485
gene id: 324925:PPHA_RS00485
uniprot id: B4SAT4
names: Activity Regulation
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.

324925:PPHA RS06775
gene id: 324925:PPHA_RS06775
uniprot id: B4S9T1
names: Similarity
messages: Belongs to the peptidase S41A family.

324925:PPHA RS02535
gene id: 324925:PPHA_RS02535
uniprot id: B4SCZ7
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

324925:PPHA RS03865
gene id: 324925:PPHA_RS03865
uniprot id: B4SEI4
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

324925:PPHA RS13830
gene id: 324925:PPHA_RS13830
uniprot id: B4SGW9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.

324925:PPHA RS02150
gene id: 324925:PPHA_RS02150
uniprot id: B4SCS2
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

324925:PPHA RS07600
gene id: 324925:PPHA_RS07600
uniprot id: B4SA87
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

324925:PPHA RS12060
gene id: 324925:PPHA_RS12060
uniprot id: B4SEV2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

324925:PPHA RS12340
gene id: 324925:PPHA_RS12340
uniprot id: B4SFA5
names: Similarity
messages: Belongs to the RelB/DinJ antitoxin family.

324925:PPHA RS05705
gene id: 324925:PPHA_RS05705
uniprot id: B4SGA7
names: Similarity
messages: Belongs to the LOG family.

324925:PPHA RS13365
gene id: 324925:PPHA_RS13365
uniprot id: B4SGD2
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SIS family. GmhA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
messages: Cytoplasm
messages: The reaction produces a racemic mixture of D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate.

324925:PPHA RS06655
gene id: 324925:PPHA_RS06655
uniprot id: B4SHD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

324925:PPHA RS11975
gene id: 324925:PPHA_RS11975
uniprot id: B4SET5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TPP enzyme family. MenD subfamily.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
messages: Homodimer.

324925:PPHA RS10265
gene id: 324925:PPHA_RS10265
uniprot id: B4SD21
names: Function
names: Similarity
messages: Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).

324925:PPHA RS12700
gene id: 324925:PPHA_RS12700
uniprot id: B4SFG4
names: Similarity
messages: Belongs to the Mg-chelatase subunit H family.

324925:PPHA RS04170
gene id: 324925:PPHA_RS04170
uniprot id: B4SEY7
names: Subcellular Location Annotation
messages: Membrane

324925:PPHA RS14310
gene id: 324925:PPHA_RS14310
uniprot id: B4SHF6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

324925:PPHA RS03500
gene id: 324925:PPHA_RS03500
uniprot id: B4SE14
names: Similarity
messages: Belongs to the peptidase M24B family.

324925:PPHA RS08725
gene id: 324925:PPHA_RS08725
uniprot id: B4SBE2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

324925:PPHA RS12940
gene id: 324925:PPHA_RS12940
uniprot id: B4SFW2
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

324925:PPHA RS00585
gene id: 324925:PPHA_RS00585
uniprot id: B4SB42
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

324925:PPHA RS02070
gene id: 324925:PPHA_RS02070
uniprot id: B4SCG2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IPP isomerase type 2 family.
messages: Cytoplasm
messages: Homooctamer. Dimer of tetramers.
messages: Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).

324925:PPHA RS09395
gene id: 324925:PPHA_RS09395
uniprot id: B4SC18
names: Subcellular Location Annotation
messages: Membrane

324925:PPHA RS09185
gene id: 324925:PPHA_RS09185
uniprot id: B4SBY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HupC/HyaC/HydC family.
messages: Membrane

324925:PPHA RS12480
gene id: 324925:PPHA_RS12480
uniprot id: B4SFC1
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

324925:PPHA RS11390
gene id: 324925:PPHA_RS11390
uniprot id: B4SE80
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

324925:PPHA RS07480
gene id: 324925:PPHA_RS07480
uniprot id: B4SA62
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

324925:PPHA RS05100
gene id: 324925:PPHA_RS05100
uniprot id: B4SFQ9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

324925:PPHA RS10395
gene id: 324925:PPHA_RS10395
uniprot id: B4SD42
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

324925:PPHA RS03625
gene id: 324925:PPHA_RS03625
uniprot id: B4SE38
names: Caution
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

324925:PPHA RS03305
gene id: 324925:PPHA_RS03305
uniprot id: B4SDX6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

324925:PPHA RS01500
gene id: 324925:PPHA_RS01500
uniprot id: B4SBV4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

324925:PPHA RS12670
gene id: 324925:PPHA_RS12670
uniprot id: B4SFF8
names: Cofactor
names: Similarity
messages: Belongs to the PyrK family.
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.

324925:PPHA RS13680
gene id: 324925:PPHA_RS13680
uniprot id: B4SGJ1
names: Subcellular Location Annotation
messages: Membrane

324925:PPHA RS07130
gene id: 324925:PPHA_RS07130
uniprot id: B4S9Z6
names: Similarity
messages: Belongs to the DprA/Smf family.

324925:PPHA RS04570
gene id: 324925:PPHA_RS04570
uniprot id: B4SF62
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Cell membrane
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.

324925:PPHA RS06035
gene id: 324925:PPHA_RS06035
uniprot id: B4SGR9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

324925:PPHA RS08215
gene id: 324925:PPHA_RS08215
uniprot id: B4SAU9
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated protein Cas5 family. Subtype I-C/Dvulg subfamily.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).

324925:PPHA RS07375
gene id: 324925:PPHA_RS07375
uniprot id: B4SA42
names: Similarity
messages: Belongs to the Nth/MutY family.

324925:PPHA RS08165
gene id: 324925:PPHA_RS08165
uniprot id: B4SAK0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

324925:PPHA RS04705
gene id: 324925:PPHA_RS04705
uniprot id: B4SFI1
names: Function
names: Similarity
messages: Belongs to the uroporphyrinogen-III synthase family.
messages: Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.

324925:PPHA RS01450
gene id: 324925:PPHA_RS01450
uniprot id: B4SBU4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

324925:PPHA RS08300
gene id: 324925:PPHA_RS08300
uniprot id: B4SAW6
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

324925:PPHA RS05845
gene id: 324925:PPHA_RS05845
uniprot id: B4SGN4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

324925:PPHA RS03670
gene id: 324925:PPHA_RS03670
uniprot id: B4SEE5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

324925:PPHA RS10175
gene id: 324925:PPHA_RS10175
uniprot id: B4SCQ4
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily.

324925:PPHA RS01965
gene id: 324925:PPHA_RS01965
uniprot id: B4SCE2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

324925:PPHA RS04715
gene id: 324925:PPHA_RS04715
uniprot id: B4SFI3
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

324925:PPHA RS03220
gene id: 324925:PPHA_RS03220
uniprot id: B4SDV9
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

324925:PPHA RS10165
gene id: 324925:PPHA_RS10165
uniprot id: B4SCQ2
names: Similarity
messages: Belongs to the HupF/HypC family.

324925:PPHA RS08930
gene id: 324925:PPHA_RS08930
uniprot id: B4SBI0
names: Function
names: Subcellular Location Annotation
messages: May play a structural or regulatory role in gas vesicle synthesis.
messages: Vesicle
messages: gas vesicle

324925:PPHA RS00620
gene id: 324925:PPHA_RS00620
uniprot id: B4SB49
names: Similarity
messages: Belongs to the UPF0047 family.

324925:PPHA RS09735
gene id: 324925:PPHA_RS09735
uniprot id: B4SCH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HupC/HyaC/HydC family.
messages: Membrane

324925:PPHA RS10745
gene id: 324925:PPHA_RS10745
uniprot id: B4SDK2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.

324925:PPHA RS02470
gene id: 324925:PPHA_RS02470
uniprot id: B4SCY4
names: Subcellular Location Annotation
messages: Membrane

324925:PPHA RS04630
gene id: 324925:PPHA_RS04630
uniprot id: B4SF73
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

324925:PPHA RS10250
gene id: 324925:PPHA_RS10250
uniprot id: B4SD18
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

324925:PPHA RS13820
gene id: 324925:PPHA_RS13820
uniprot id: B4SGW7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

324925:PPHA RS02255
gene id: 324925:PPHA_RS02255
uniprot id: B4SCU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

324925:PPHA RS02835
gene id: 324925:PPHA_RS02835
uniprot id: B4SDE4
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.
messages: Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

324925:PPHA RS09505
gene id: 324925:PPHA_RS09505
uniprot id: B4SC34
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

324925:PPHA RS08130
gene id: 324925:PPHA_RS08130
uniprot id: B4SAJ3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

324925:PPHA RS04300
gene id: 324925:PPHA_RS04300
uniprot id: B4SF09
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

324925:PPHA RS07115
gene id: 324925:PPHA_RS07115
uniprot id: B4S9Z3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD.
messages: Belongs to the RecD family.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

324925:PPHA RS05115
gene id: 324925:PPHA_RS05115
uniprot id: B4SFR2
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

324925:PPHA RS08230
gene id: 324925:PPHA_RS08230
uniprot id: B4SAV2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated exonuclease Cas4 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).
messages: Mg(2+) or Mn(2+) required for ssDNA cleavage activity.

324925:PPHA RS02825
gene id: 324925:PPHA_RS02825
uniprot id: B4SDE2
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

324925:PPHA RS03370
gene id: 324925:PPHA_RS03370
uniprot id: B4SDY8
names: PTM
messages: Binds 1 heme group per subunit.

324925:PPHA RS12100
gene id: 324925:PPHA_RS12100
uniprot id: B4SEW0
names: Similarity
messages: Belongs to the CRISPR-associated Csm4 family.

324925:PPHA RS06845
gene id: 324925:PPHA_RS06845
uniprot id: B4S9U5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.

324925:PPHA RS08210
gene id: 324925:PPHA_RS08210
uniprot id: B4SAU8
names: Similarity
messages: In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.
messages: In the central section; belongs to the CRISPR-associated helicase Cas3 family.

324925:PPHA RS14025
gene id: 324925:PPHA_RS14025
uniprot id: B4SH06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

324925:PPHA RS05505
gene id: 324925:PPHA_RS05505
uniprot id: B4SG78
names: Similarity
messages: Belongs to the phD/YefM antitoxin family.

324925:PPHA RS01060
gene id: 324925:PPHA_RS01060
uniprot id: B4SBC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

324925:PPHA RS11195
gene id: 324925:PPHA_RS11195
uniprot id: B4SDU2
names: Similarity
messages: Belongs to the arylamine N-acetyltransferase family.

324925:PPHA RS13785
gene id: 324925:PPHA_RS13785
uniprot id: B4SGW0
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

324925:PPHA RS11940
gene id: 324925:PPHA_RS11940
uniprot id: B4SES9
names: Similarity
messages: Belongs to the citrate synthase family.

324925:PPHA RS11875
gene id: 324925:PPHA_RS11875
uniprot id: B4SER6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

324925:PPHA RS10440
gene id: 324925:PPHA_RS10440
uniprot id: B4SD51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

324925:PPHA RS11620
gene id: 324925:PPHA_RS11620
uniprot id: B4SEC4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

324925:PPHA RS00910
gene id: 324925:PPHA_RS00910
uniprot id: B4SB95
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

324925:PPHA RS00170
gene id: 324925:PPHA_RS00170
uniprot id: B4SAM5
names: Similarity
messages: Belongs to the HdrA family.

324925:PPHA RS10750
gene id: 324925:PPHA_RS10750
uniprot id: B4SDK3
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

324925:PPHA RS05450
gene id: 324925:PPHA_RS05450
uniprot id: B4SG68
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

324925:PPHA RS01570
gene id: 324925:PPHA_RS01570
uniprot id: B4SBW7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell inner membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

324925:PPHA RS04365
gene id: 324925:PPHA_RS04365
uniprot id: B4SF22
names: Similarity
messages: Belongs to the UPF0251 family.

324925:PPHA RS11480
gene id: 324925:PPHA_RS11480
uniprot id: B4SE98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsrC/TusE family.
messages: Cytoplasm

324925:PPHA RS09245
gene id: 324925:PPHA_RS09245
uniprot id: B4SBZ2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

324925:PPHA RS11540
gene id: 324925:PPHA_RS11540
uniprot id: B4SEB0
names: Similarity
messages: Belongs to the RuBisCO large chain family.

324925:PPHA RS09340
gene id: 324925:PPHA_RS09340
uniprot id: B4SC09
names: Subcellular Location Annotation
messages: Membrane

324925:PPHA RS00430
gene id: 324925:PPHA_RS00430
uniprot id: B4SAS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

324925:PPHA RS01625
gene id: 324925:PPHA_RS01625
uniprot id: B4SC73
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

324925:PPHA RS04260
gene id: 324925:PPHA_RS04260
uniprot id: B4SF01
names: Cofactor
names: Similarity
messages: Belongs to the PdaD family.
messages: Belongs to the pyruvoyl-dependent arginine decarboxylase family.
messages: Binds 1 pyruvoyl group covalently per subunit.

324925:PPHA RS04015
gene id: 324925:PPHA_RS04015
uniprot id: B4SEL2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SoxA family.
messages: Binds 1 heme group per subunit.
messages: Binds 2 heme groups per subunit.
messages: C-type monoheme cytochrome, which is part of the SoxAX cytochrome complex involved in sulfur oxidation. The SoxAX complex catalyzes the formation of a heterodisulfide bond between the conserved cysteine residue on a sulfur carrier SoxYZ complex subunit SoxY and thiosulfate or other inorganic sulfur substrates. This leads to the liberation of two electrons, which may be transferred from the SoxAX complex to another cytochrome c and which then may be used for reductive CO(2) fixation.
messages: Heterodimer of SoxA and SoxX.
messages: Periplasm

324925:PPHA RS03815
gene id: 324925:PPHA_RS03815
uniprot id: B4SEH4
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

324925:PPHA RS08980
gene id: 324925:PPHA_RS08980
uniprot id: B4SBI9
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

324925:PPHA RS05070
gene id: 324925:PPHA_RS05070
uniprot id: B4SFQ3
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the ferredoxin--NADP reductase type 2 family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

324925:PPHA RS14150
gene id: 324925:PPHA_RS14150
uniprot id: B4SH31
names: Similarity
messages: Belongs to the deoxyhypusine synthase family.

324925:PPHA RS01515
gene id: 324925:PPHA_RS01515
uniprot id: B4SBV7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

324925:PPHA RS14240
gene id: 324925:PPHA_RS14240
uniprot id: B4SH48
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

324925:PPHA RS04655
gene id: 324925:PPHA_RS04655
uniprot id: B4SF79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TPS (TC 1.B.20) family.
messages: Cell outer membrane
messages: Membrane

324925:PPHA RS07990
gene id: 324925:PPHA_RS07990
uniprot id: B4SAG7
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

324925:PPHA RS12245
gene id: 324925:PPHA_RS12245
uniprot id: B4SF86
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

324925:PPHA RS03400
gene id: 324925:PPHA_RS03400
uniprot id: B4SDZ4
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HPrK/P family.
messages: Both phosphorylation and phosphorolysis are carried out by the same active site and suggest a common mechanism for both reactions.
messages: Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr).
messages: Homohexamer.
messages: The Walker A ATP-binding motif also binds Pi and PPi.

324925:PPHA RS05925
gene id: 324925:PPHA_RS05925
uniprot id: B4SGP8
names: Similarity
messages: Belongs to the SAICAR synthetase family.

324925:PPHA RS11715
gene id: 324925:PPHA_RS11715
uniprot id: B4SEE3
names: Similarity
messages: Belongs to the SAM hydrolase / SAM-dependent halogenase family.

324925:PPHA RS10300
gene id: 324925:PPHA_RS10300
uniprot id: B4SD29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

324925:PPHA RS12065
gene id: 324925:PPHA_RS12065
uniprot id: B4SEV3
names: Cofactor
names: Function
messages: Accepts electrons from ETF and reduces ubiquinone.
messages: Binds 1 [4Fe-4S] cluster.

324925:PPHA RS03275
gene id: 324925:PPHA_RS03275
uniprot id: B4SDX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TspO/BZRP family.
messages: Membrane

324925:PPHA RS06295
gene id: 324925:PPHA_RS06295
uniprot id: B4SH63
names: Function
messages: Decarboxylates L-threonine-O-3-phosphate to yield (R)-1-amino-2-propanol O-2-phosphate, the precursor for the linkage between the nucleotide loop and the corrin ring in cobalamin.

324925:PPHA RS02110
gene id: 324925:PPHA_RS02110
uniprot id: B4SCG9
names: Similarity
messages: Belongs to the phosphohexose mutase family.

324925:PPHA RS13965
gene id: 324925:PPHA_RS13965
uniprot id: B4SGZ4
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily.
messages: Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway.

324925:PPHA RS10205
gene id: 324925:PPHA_RS10205
uniprot id: B4SCR2
names: Similarity
messages: Belongs to the universal stress protein A family.

324925:PPHA RS07605
gene id: 324925:PPHA_RS07605
uniprot id: B4SA88
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell inner membrane
messages: Forms a complex with TatA.
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.

324925:PPHA RS08940
gene id: 324925:PPHA_RS08940
uniprot id: B4SBI2
names: Function
names: Subcellular Location Annotation
messages: May play a structural or regulatory role in gas vesicle synthesis.
messages: Vesicle
messages: gas vesicle

324925:PPHA RS11870
gene id: 324925:PPHA_RS11870
uniprot id: B4SER5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

324925:PPHA RS12675
gene id: 324925:PPHA_RS12675
uniprot id: B4SFF9
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

324925:PPHA RS08690
gene id: 324925:PPHA_RS08690
uniprot id: B4SBD5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
messages: Cytoplasm

324925:PPHA RS10880
gene id: 324925:PPHA_RS10880
uniprot id: B4SDM8
names: Subcellular Location Annotation
messages: Membrane

324925:PPHA RS05105
gene id: 324925:PPHA_RS05105
uniprot id: B4SFR0
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: This protein binds to 23S rRNA in the presence of protein L20.

324925:PPHA RS00340
gene id: 324925:PPHA_RS00340
uniprot id: B4SAQ7
names: Caution
names: Cofactor
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

324925:PPHA RS10325
gene id: 324925:PPHA_RS10325
uniprot id: B4SD33
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

324925:PPHA RS05245
gene id: 324925:PPHA_RS05245
uniprot id: B4SG30
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell inner membrane
messages: Membrane

324925:PPHA RS08910
gene id: 324925:PPHA_RS08910
uniprot id: B4SBH6
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

324925:PPHA RS04640
gene id: 324925:PPHA_RS04640
uniprot id: B4SF75
names: Similarity
messages: Belongs to the UPF0758 family.

324925:PPHA RS03260
gene id: 324925:PPHA_RS03260
uniprot id: B4SDW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

324925:PPHA RS00540
gene id: 324925:PPHA_RS00540
uniprot id: B4SAU0
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

324925:PPHA RS06525
gene id: 324925:PPHA_RS06525
uniprot id: B4SHA9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell inner membrane
messages: Cytoplasm
messages: May bind 1 zinc ion per subunit.
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

324925:PPHA RS11165
gene id: 324925:PPHA_RS11165
uniprot id: B4SDT6
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

324925:PPHA RS11645
gene id: 324925:PPHA_RS11645
uniprot id: B4SEC9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

324925:PPHA RS02425
gene id: 324925:PPHA_RS02425
uniprot id: B4SCX5
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

324925:PPHA RS09975
gene id: 324925:PPHA_RS09975
uniprot id: B4SCL9
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

324925:PPHA RS12020
gene id: 324925:PPHA_RS12020
uniprot id: B4SEU4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MenH family.
messages: Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC).
messages: Monomer.

324925:PPHA RS12030
gene id: 324925:PPHA_RS12030
uniprot id: B4SEU6
names: Function
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 1 subfamily.
messages: Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 2-succinylbenzoate (OSB).

324925:PPHA RS11695
gene id: 324925:PPHA_RS11695
uniprot id: B4SED8
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

324925:PPHA RS08710
gene id: 324925:PPHA_RS08710
uniprot id: B4SBD9
names: Domain
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the CobB/CbiA family.
messages: Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source.
messages: Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP and cobyrinate and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.
messages: The a and c carboxylates of cobyrinate are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CbiA catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate.

324925:PPHA RS07625
gene id: 324925:PPHA_RS07625
uniprot id: B4SA92
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

324925:PPHA RS11860
gene id: 324925:PPHA_RS11860
uniprot id: B4SER3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

324925:PPHA RS05380
gene id: 324925:PPHA_RS05380
uniprot id: B4SG54
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

324925:PPHA RS14315
gene id: 324925:PPHA_RS14315
uniprot id: B4SHF7
names: Subcellular Location Annotation
messages: Membrane

324925:PPHA RS03680
gene id: 324925:PPHA_RS03680
uniprot id: B4SEE7
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

324925:PPHA RS13880
gene id: 324925:PPHA_RS13880
uniprot id: B4SGX9
names: Similarity
messages: Belongs to the aspartokinase family.

324925:PPHA RS11670
gene id: 324925:PPHA_RS11670
uniprot id: B4SED4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

324925:PPHA RS00365
gene id: 324925:PPHA_RS00365
uniprot id: B4SAR2
names: Cofactor
names: Function
messages: Binds 2 [4Fe-4S] clusters. In this family the first cluster has a non-standard and varying [4Fe-4S] binding motif CX(2)CX(2)CX(4-5)CP.
messages: Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.

324925:PPHA RS10450
gene id: 324925:PPHA_RS10450
uniprot id: B4SD53
names: Similarity
messages: Belongs to the ArsC family.

324925:PPHA RS05095
gene id: 324925:PPHA_RS05095
uniprot id: B4SFQ8
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 3 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

324925:PPHA RS02660
gene id: 324925:PPHA_RS02660
uniprot id: B4SDB7
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

324925:PPHA RS01575
gene id: 324925:PPHA_RS01575
uniprot id: B4SBW8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

324925:PPHA RS06370
gene id: 324925:PPHA_RS06370
uniprot id: B4SH78
names: Subcellular Location Annotation
messages: Membrane

324925:PPHA RS13865
gene id: 324925:PPHA_RS13865
uniprot id: B4SGX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

324925:PPHA RS01990
gene id: 324925:PPHA_RS01990
uniprot id: B4SCE7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

324925:PPHA RS02775
gene id: 324925:PPHA_RS02775
uniprot id: B4SDD2
names: Similarity
messages: Belongs to the polysaccharide synthase family.

324925:PPHA RS07790
gene id: 324925:PPHA_RS07790
uniprot id: B4SAD1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Molecular chaperone. Has ATPase activity.

324925:PPHA RS08985
gene id: 324925:PPHA_RS08985
uniprot id: B4SBJ0
names: Function
names: Similarity
messages: Belongs to the gas vesicle protein type A family.
messages: Gas vesicles are small, hollow, gas filled protein structures that are found in several microbial planktonic microorganisms. They allow the positioning of the organism at the favorable depth for growth.

324925:PPHA RS00600
gene id: 324925:PPHA_RS00600
uniprot id: B4SB45
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

324925:PPHA RS08795
gene id: 324925:PPHA_RS08795
uniprot id: B4SBF6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

324925:PPHA RS00420
gene id: 324925:PPHA_RS00420
uniprot id: B4SAS1
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

324925:PPHA RS01445
gene id: 324925:PPHA_RS01445
uniprot id: B4SBU3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

324925:PPHA RS03285
gene id: 324925:PPHA_RS03285
uniprot id: B4SDX2
names: Caution
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

324925:PPHA RS14195
gene id: 324925:PPHA_RS14195
uniprot id: B4SH39
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase C chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has four main subunits: a(1), b(1), b'(1) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta, b and b' chains.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

324925:PPHA RS04195
gene id: 324925:PPHA_RS04195
uniprot id: B4SEZ2
names: Cofactor
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.

324925:PPHA RS04135
gene id: 324925:PPHA_RS04135
uniprot id: B4SEN7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

324925:PPHA RS09060
gene id: 324925:PPHA_RS09060
uniprot id: B4SBK5
names: Subcellular Location Annotation
messages: Membrane

324925:PPHA RS01460
gene id: 324925:PPHA_RS01460
uniprot id: B4SBU6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

324925:PPHA RS12095
gene id: 324925:PPHA_RS12095
uniprot id: B4SEV9
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated Csm5 family.
messages: This subunit might be involved in maturation of a crRNA intermediate to its mature form.

324925:PPHA RS04110
gene id: 324925:PPHA_RS04110
uniprot id: B4SEN1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

324925:PPHA RS03590
gene id: 324925:PPHA_RS03590
uniprot id: B4SE31
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.

324925:PPHA RS13305
gene id: 324925:PPHA_RS13305
uniprot id: B4SGC1
names: Cofactor
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.

324925:PPHA RS01005
gene id: 324925:PPHA_RS01005
uniprot id: B4SBB1
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

324925:PPHA RS06605
gene id: 324925:PPHA_RS06605
uniprot id: B4SHC4
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

324925:PPHA RS03375
gene id: 324925:PPHA_RS03375
uniprot id: B4SDY9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm

324925:PPHA RS08840
gene id: 324925:PPHA_RS08840
uniprot id: B4SBG5
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

324925:PPHA RS05155
gene id: 324925:PPHA_RS05155
uniprot id: B4SFR9
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

324925:PPHA RS04620
gene id: 324925:PPHA_RS04620
uniprot id: B4SF71
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.

324925:PPHA RS00355
gene id: 324925:PPHA_RS00355
uniprot id: B4SAR0
names: Function
names: Similarity
messages: Belongs to the phenylacetyl-CoA ligase family.
messages: Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).

324925:PPHA RS14475
gene id: 324925:PPHA_RS14475
uniprot id: B4SDU9
names: Similarity
messages: Belongs to the glycosyltransferase 41 family. O-GlcNAc transferase subfamily.

324925:PPHA RS14255
gene id: 324925:PPHA_RS14255
uniprot id: B4SHE6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

324925:PPHA RS05715
gene id: 324925:PPHA_RS05715
uniprot id: B4SGK7
names: Subcellular Location Annotation
messages: Membrane

324925:PPHA RS00310
gene id: 324925:PPHA_RS00310
uniprot id: B4SAQ2
names: Similarity
messages: Belongs to the universal stress protein A family.

324925:PPHA RS00670
gene id: 324925:PPHA_RS00670
uniprot id: B4SB55
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

324925:PPHA RS08250
gene id: 324925:PPHA_RS08250
uniprot id: B4SAV6
names: Function
names: Similarity
messages: Belongs to the transposase 11 family.
messages: Involved in the transposition of the insertion sequence IS5.

324925:PPHA RS05860
gene id: 324925:PPHA_RS05860
uniprot id: B4SGN7
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

324925:PPHA RS09995
gene id: 324925:PPHA_RS09995
uniprot id: B4SCM1
names: Subcellular Location Annotation
messages: Membrane

324925:PPHA RS11970
gene id: 324925:PPHA_RS11970
uniprot id: B4SET4
names: Function
names: Similarity
messages: Belongs to the isochorismate synthase family.
messages: Catalyzes the conversion of chorismate to isochorismate.

324925:PPHA RS05365
gene id: 324925:PPHA_RS05365
uniprot id: B4SG51
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.
messages: Cytoplasm
messages: Homodimer.

324925:PPHA RS11110
gene id: 324925:PPHA_RS11110
uniprot id: B4SDS5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.

324925:PPHA RS01125
gene id: 324925:PPHA_RS01125
uniprot id: B4SBN2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

324925:PPHA RS03390
gene id: 324925:PPHA_RS03390
uniprot id: B4SDZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

324925:PPHA RS06040
gene id: 324925:PPHA_RS06040
uniprot id: B4SGS0
names: Subcellular Location Annotation
messages: Membrane

324925:PPHA RS13310
gene id: 324925:PPHA_RS13310
uniprot id: B4SGC2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 51 family.
messages: Cell inner membrane
messages: Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors.

324925:PPHA RS04710
gene id: 324925:PPHA_RS04710
uniprot id: B4SFI2
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

324925:PPHA RS13215
gene id: 324925:PPHA_RS13215
uniprot id: B4SG16
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

324925:PPHA RS07405
gene id: 324925:PPHA_RS07405
uniprot id: B4SA47
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

324925:PPHA RS06860
gene id: 324925:PPHA_RS06860
uniprot id: B4S9U8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

324925:PPHA RS00185
gene id: 324925:PPHA_RS00185
uniprot id: B4SAM9
names: Similarity
messages: Belongs to the sulfate adenylyltransferase family.

324925:PPHA RS01020
gene id: 324925:PPHA_RS01020
uniprot id: B4SBB4
names: Similarity
messages: Belongs to the fabD family.

324925:PPHA RS13120
gene id: 324925:PPHA_RS13120
uniprot id: B4SFZ6
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

324925:PPHA RS14000
gene id: 324925:PPHA_RS14000
uniprot id: B4SH01
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

324925:PPHA RS06280
gene id: 324925:PPHA_RS06280
uniprot id: B4SH60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

324925:PPHA RS06565
gene id: 324925:PPHA_RS06565
uniprot id: B4SHB6
names: Subcellular Location Annotation
messages: Membrane

324925:PPHA RS03585
gene id: 324925:PPHA_RS03585
uniprot id: B4SE30
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

324925:PPHA RS12595
gene id: 324925:PPHA_RS12595
uniprot id: B4SFE3
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

324925:PPHA RS04670
gene id: 324925:PPHA_RS04670
uniprot id: B4SFH4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

324925:PPHA RS01835
gene id: 324925:PPHA_RS01835
uniprot id: B4SCB6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

324925:PPHA RS06030
gene id: 324925:PPHA_RS06030
uniprot id: B4SGR8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

324925:PPHA RS08310
gene id: 324925:PPHA_RS08310
uniprot id: B4SAW8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

324925:PPHA RS07440
gene id: 324925:PPHA_RS07440
uniprot id: B4SA54
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).

324925:PPHA RS02165
gene id: 324925:PPHA_RS02165
uniprot id: B4SCS5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

324925:PPHA RS00415
gene id: 324925:PPHA_RS00415
uniprot id: B4SAS0
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

324925:PPHA RS02125
gene id: 324925:PPHA_RS02125
uniprot id: B4SCR8
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

324925:PPHA RS08845
gene id: 324925:PPHA_RS08845
uniprot id: B4SBG6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

324925:PPHA RS07980
gene id: 324925:PPHA_RS07980
uniprot id: B4SAG5
names: Cofactor
messages: Binds 2 magnesium ions per subunit.

324925:PPHA RS13870
gene id: 324925:PPHA_RS13870
uniprot id: B4SGX7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell inner membrane
messages: Probably interacts with PlsX.

324925:PPHA RS10690
gene id: 324925:PPHA_RS10690
uniprot id: B4SDA0
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

324925:PPHA RS09235
gene id: 324925:PPHA_RS09235
uniprot id: B4SBZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

324925:PPHA RS06885
gene id: 324925:PPHA_RS06885
uniprot id: B4S9V4
names: Subcellular Location Annotation
messages: Membrane

324925:PPHA RS07425
gene id: 324925:PPHA_RS07425
uniprot id: B4SA51
names: Similarity
messages: Belongs to the peptidase S41A family.

324925:PPHA RS06855
gene id: 324925:PPHA_RS06855
uniprot id: B4S9U7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

324925:PPHA RS11925
gene id: 324925:PPHA_RS11925
uniprot id: B4SES6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

324925:PPHA RS09815
gene id: 324925:PPHA_RS09815
uniprot id: B4SCI7
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

324925:PPHA RS05085
gene id: 324925:PPHA_RS05085
uniprot id: B4SFQ6
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

324925:PPHA RS04675
gene id: 324925:PPHA_RS04675
uniprot id: B4SFH5
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

324925:PPHA RS07345
gene id: 324925:PPHA_RS07345
uniprot id: B4SA36
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

324925:PPHA RS01905
gene id: 324925:PPHA_RS01905
uniprot id: B4SCD0
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

324925:PPHA RS05945
gene id: 324925:PPHA_RS05945
uniprot id: B4SGQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

324925:PPHA RS04105
gene id: 324925:PPHA_RS04105
uniprot id: B4SEN0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

324925:PPHA RS12280
gene id: 324925:PPHA_RS12280
uniprot id: B4SF93
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

324925:PPHA RS13715
gene id: 324925:PPHA_RS13715
uniprot id: B4SGJ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgE subfamily.
messages: Homodimer.
messages: Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1->4)-glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB.

324925:PPHA RS11455
gene id: 324925:PPHA_RS11455
uniprot id: B4SE93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsrE/TusD family.
messages: Cytoplasm

324925:PPHA RS14155
gene id: 324925:PPHA_RS14155
uniprot id: B4SH32
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

324925:PPHA RS01540
gene id: 324925:PPHA_RS01540
uniprot id: B4SBW1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

324925:PPHA RS06890
gene id: 324925:PPHA_RS06890
uniprot id: B4S9V5
names: Subcellular Location Annotation
messages: Membrane

324925:PPHA RS08030
gene id: 324925:PPHA_RS08030
uniprot id: B4SAH3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

324925:PPHA RS09230
gene id: 324925:PPHA_RS09230
uniprot id: B4SBY9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

324925:PPHA RS10835
gene id: 324925:PPHA_RS10835
uniprot id: B4SDM0
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

324925:PPHA RS08890
gene id: 324925:PPHA_RS08890
uniprot id: B4SBH2
names: Similarity
messages: Belongs to the Mg-chelatase subunit H family.

324925:PPHA RS13915
gene id: 324925:PPHA_RS13915
uniprot id: B4SGY6
names: Similarity
messages: Belongs to the UPF0175 family.

324925:PPHA RS03545
gene id: 324925:PPHA_RS03545
uniprot id: B4SE22
names: Subcellular Location Annotation
messages: Membrane

324925:PPHA RS09240
gene id: 324925:PPHA_RS09240
uniprot id: B4SBZ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 30 kDa subunit family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

324925:PPHA RS04565
gene id: 324925:PPHA_RS04565
uniprot id: B4SF61
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

324925:PPHA RS10860
gene id: 324925:PPHA_RS10860
uniprot id: B4SDM5
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

324925:PPHA RS10155
gene id: 324925:PPHA_RS10155
uniprot id: B4SCQ0
names: Similarity
messages: Belongs to the HypE family.

324925:PPHA RS05750
gene id: 324925:PPHA_RS05750
uniprot id: B4SGL5
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily.
messages: Binds 1 NADP(+) per subunit.
messages: Catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose.
messages: Contains a large N-terminal NADP-binding domain, and a smaller C-terminal substrate-binding domain.
messages: Homopentamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

324925:PPHA RS09915
gene id: 324925:PPHA_RS09915
uniprot id: B4SCK7
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

324925:PPHA RS13985
gene id: 324925:PPHA_RS13985
uniprot id: B4SGZ8
names: Function
names: Similarity
messages: Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor.
messages: Belongs to the biotin--protein ligase family.

324925:PPHA RS11300
gene id: 324925:PPHA_RS11300
uniprot id: B4SE63
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

324925:PPHA RS02215
gene id: 324925:PPHA_RS02215
uniprot id: B4SCT5
names: Function
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

324925:PPHA RS02315
gene id: 324925:PPHA_RS02315
uniprot id: B4SCV5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

324925:PPHA RS06375
gene id: 324925:PPHA_RS06375
uniprot id: B4SH79
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

324925:PPHA RS02340
gene id: 324925:PPHA_RS02340
uniprot id: B4SCV9
names: Subcellular Location Annotation
messages: Membrane

324925:PPHA RS07985
gene id: 324925:PPHA_RS07985
uniprot id: B4SAG6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

324925:PPHA RS05700
gene id: 324925:PPHA_RS05700
uniprot id: B4SGA6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Belongs to the peroxiredoxin family. Prx6 subfamily.
messages: Cytoplasm
messages: Homodecamer. Pentamer of dimers that assemble into a ring structure.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. Although the primary sequence of this enzyme is similar to those of the 1-Cys Prx6 enzymes, its catalytic properties resemble those of the typical 2-Cys Prxs and C(R) is provided by the other dimeric subunit to form an intersubunit disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

324925:PPHA RS01725
gene id: 324925:PPHA_RS01725
uniprot id: B4SC93
names: Function
names: Similarity
messages: Belongs to the transposase 11 family.
messages: Involved in the transposition of the insertion sequence IS5.