323850:SHEW RS02545
gene id: 323850:SHEW_RS02545
uniprot id: A3QA70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell inner membrane
messages: Membrane

323850:SHEW RS07735
gene id: 323850:SHEW_RS07735
uniprot id: A3QD13
names: Function
names: Similarity
messages: Belongs to the N(4)-acetylcytidine amidohydrolase family.
messages: Catalyzes the hydrolysis of N(4)-acetylcytidine (ac4C).

323850:SHEW RS11140
gene id: 323850:SHEW_RS11140
uniprot id: A3QEW5
names: Similarity
messages: Belongs to the ACC deaminase/D-cysteine desulfhydrase family.

323850:SHEW RS15585
gene id: 323850:SHEW_RS15585
uniprot id: A3QHC9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

323850:SHEW RS09945
gene id: 323850:SHEW_RS09945
uniprot id: A3QE90
names: Similarity
messages: Belongs to the phosphohexose mutase family.

323850:SHEW RS07020
gene id: 323850:SHEW_RS07020
uniprot id: A3QCN8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Cell inner membrane
messages: FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

323850:SHEW RS14165
gene id: 323850:SHEW_RS14165
uniprot id: A3QGK9
names: Similarity
messages: Belongs to the glutathione peroxidase family.

323850:SHEW RS17995
gene id: 323850:SHEW_RS17995
uniprot id: A3QIN8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

323850:SHEW RS05975
gene id: 323850:SHEW_RS05975
uniprot id: A3QC33
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

323850:SHEW RS10470
gene id: 323850:SHEW_RS10470
uniprot id: A3QEJ0
names: Function
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.
messages: DNA-dependent ATPase that plays important roles in cellular responses to stalled DNA replication processes.

323850:SHEW RS12465
gene id: 323850:SHEW_RS12465
uniprot id: A3QFM5
names: Similarity
messages: Belongs to the peptidase S49 family.

323850:SHEW RS16385
gene id: 323850:SHEW_RS16385
uniprot id: A3QHT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

323850:SHEW RS11985
gene id: 323850:SHEW_RS11985
uniprot id: A3QFD4
names: Function
names: Similarity
messages: A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.
messages: Belongs to the NifU family.

323850:SHEW RS17045
gene id: 323850:SHEW_RS17045
uniprot id: A3QI62
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

323850:SHEW RS00545
gene id: 323850:SHEW_RS00545
uniprot id: A3Q933
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

323850:SHEW RS10480
gene id: 323850:SHEW_RS10480
uniprot id: A3QEJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Membrane

323850:SHEW RS01155
gene id: 323850:SHEW_RS01155
uniprot id: A3Q9E5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

323850:SHEW RS00820
gene id: 323850:SHEW_RS00820
uniprot id: A3Q980
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

323850:SHEW RS02420
gene id: 323850:SHEW_RS02420
uniprot id: A3QA45
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

323850:SHEW RS05715
gene id: 323850:SHEW_RS05715
uniprot id: A3QBY3
names: Similarity
messages: Belongs to the P(II) protein family.

323850:SHEW RS01080
gene id: 323850:SHEW_RS01080
uniprot id: A3Q9D0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

323850:SHEW RS10055
gene id: 323850:SHEW_RS10055
uniprot id: A3QEB0
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

323850:SHEW RS05230
gene id: 323850:SHEW_RS05230
uniprot id: A3QBN6
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

323850:SHEW RS08200
gene id: 323850:SHEW_RS08200
uniprot id: A3QD98
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

323850:SHEW RS08320
gene id: 323850:SHEW_RS08320
uniprot id: A3QDC3
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

323850:SHEW RS15880
gene id: 323850:SHEW_RS15880
uniprot id: A3QHI7
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

323850:SHEW RS15840
gene id: 323850:SHEW_RS15840
uniprot id: A3QHI0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

323850:SHEW RS07350
gene id: 323850:SHEW_RS07350
uniprot id: A3QCV3
names: Similarity
messages: Belongs to the UDPGP type 2 family.

323850:SHEW RS18705
gene id: 323850:SHEW_RS18705
uniprot id: A3QJ27
names: Similarity
messages: Belongs to the GSP N family.

323850:SHEW RS08925
gene id: 323850:SHEW_RS08925
uniprot id: A3QDP2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane

323850:SHEW RS11720
gene id: 323850:SHEW_RS11720
uniprot id: A3QF81
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

323850:SHEW RS10810
gene id: 323850:SHEW_RS10810
uniprot id: A3QEQ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. CmoB family.
messages: Catalyzes carboxymethyl transfer from carboxy-S-adenosyl-L-methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5-carboxymethoxyuridine (cmo5U) at position 34 in tRNAs.
messages: Homotetramer.

323850:SHEW RS19195
gene id: 323850:SHEW_RS19195
uniprot id: A3QJC4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. KdkA/RfaP family.
messages: Catalyzes the ATP-dependent phosphorylation of the 3-deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position.
messages: Cell inner membrane
messages: Membrane

323850:SHEW RS08710
gene id: 323850:SHEW_RS08710
uniprot id: A3QDK1
names: Similarity
names: Subunit
messages: Belongs to the RNase H family.
messages: Monomer.

323850:SHEW RS04080
gene id: 323850:SHEW_RS04080
uniprot id: A3QB14
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.

323850:SHEW RS01690
gene id: 323850:SHEW_RS01690
uniprot id: A3Q9P9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

323850:SHEW RS13910
gene id: 323850:SHEW_RS13910
uniprot id: A3QGF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

323850:SHEW RS03030
gene id: 323850:SHEW_RS03030
uniprot id: A3QAG3
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.

323850:SHEW RS19365
gene id: 323850:SHEW_RS19365
uniprot id: A3QJF4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

323850:SHEW RS17790
gene id: 323850:SHEW_RS17790
uniprot id: A3QIK9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

323850:SHEW RS16570
gene id: 323850:SHEW_RS16570
uniprot id: A3QHX0
names: Subcellular Location Annotation
messages: Membrane

323850:SHEW RS17920
gene id: 323850:SHEW_RS17920
uniprot id: A3QIM3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

323850:SHEW RS01235
gene id: 323850:SHEW_RS01235
uniprot id: A3Q9G1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

323850:SHEW RS15155
gene id: 323850:SHEW_RS15155
uniprot id: A3QH48
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LptE lipoprotein family.
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptD.
messages: Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane.

323850:SHEW RS15865
gene id: 323850:SHEW_RS15865
uniprot id: A3QHI4
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

323850:SHEW RS14455
gene id: 323850:SHEW_RS14455
uniprot id: A3QGR8
names: Similarity
messages: Belongs to the DEAD box helicase family.

323850:SHEW RS08460
gene id: 323850:SHEW_RS08460
uniprot id: A3QDF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

323850:SHEW RS14560
gene id: 323850:SHEW_RS14560
uniprot id: A3QGT9
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cell membrane
messages: Homodimer.
messages: May be involved in cell division.

323850:SHEW RS11685
gene id: 323850:SHEW_RS11685
uniprot id: A3QF74
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

323850:SHEW RS00780
gene id: 323850:SHEW_RS00780
uniprot id: A3Q972
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

323850:SHEW RS05485
gene id: 323850:SHEW_RS05485
uniprot id: A3QBT7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

323850:SHEW RS05785
gene id: 323850:SHEW_RS05785
uniprot id: A3QBZ5
names: Function
names: Similarity
messages: Belongs to the Fe(2+)-trafficking protein family.
messages: Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.

323850:SHEW RS11080
gene id: 323850:SHEW_RS11080
uniprot id: A3QEV2
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

323850:SHEW RS11475
gene id: 323850:SHEW_RS11475
uniprot id: A3QF32
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

323850:SHEW RS18755
gene id: 323850:SHEW_RS18755
uniprot id: A3QJ37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial secretin family. GSP D subfamily.
messages: Cell outer membrane
messages: Membrane

323850:SHEW RS09635
gene id: 323850:SHEW_RS09635
uniprot id: A3QE30
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M20A family. DapE subfamily.
messages: Binds 2 Zn(2+) or Co(2+) ions per subunit.
messages: Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
messages: Homodimer.

323850:SHEW RS15750
gene id: 323850:SHEW_RS15750
uniprot id: A3QHG2
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

323850:SHEW RS04140
gene id: 323850:SHEW_RS04140
uniprot id: A3QB26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

323850:SHEW RS16340
gene id: 323850:SHEW_RS16340
uniprot id: A3QHS4
names: Subcellular Location Annotation
messages: Periplasm

323850:SHEW RS01385
gene id: 323850:SHEW_RS01385
uniprot id: A3Q9J1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ZapB family.
messages: Cytoplasm
messages: Homodimer. The ends of the coiled-coil dimer bind to each other, forming polymers. Interacts with FtsZ.
messages: Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA.

323850:SHEW RS03445
gene id: 323850:SHEW_RS03445
uniprot id: A3QAP5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phospholipase A1 family.
messages: Binds 1 Ca(2+) ion per monomer. In the dimeric form the Ca(2+) is bound by different amino acids with binding of each Ca(2+) shared with ligands coming from each monomer. The Ca(2+) ion may have a role in catalysis.
messages: Cell outer membrane
messages: Homodimer; dimerization is reversible, and the dimeric form is the active one.
messages: Hydrolysis of phosphatidylcholine with phospholipase A2 (EC 3.1.1.4) and phospholipase A1 (EC 3.1.1.32) activities.
messages: Membrane

323850:SHEW RS00445
gene id: 323850:SHEW_RS00445
uniprot id: A3Q912
names: Function
names: Similarity
messages: Belongs to the MoaB/Mog family.
messages: May be involved in the biosynthesis of molybdopterin.

323850:SHEW RS14880
gene id: 323850:SHEW_RS14880
uniprot id: A3QH01
names: Similarity
messages: Belongs to the BolA/IbaG family.

323850:SHEW RS00090
gene id: 323850:SHEW_RS00090
uniprot id: A3Q8U1
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

323850:SHEW RS05920
gene id: 323850:SHEW_RS05920
uniprot id: A3QC22
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

323850:SHEW RS15030
gene id: 323850:SHEW_RS15030
uniprot id: A3QH31
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

323850:SHEW RS08435
gene id: 323850:SHEW_RS08435
uniprot id: A3QDE6
names: Similarity
messages: Belongs to the UPF0227 family.

323850:SHEW RS09920
gene id: 323850:SHEW_RS09920
uniprot id: A3QE85
names: Function
names: Similarity
messages: Belongs to the flavodoxin family.
messages: Low-potential electron donor to a number of redox enzymes.

323850:SHEW RS18545
gene id: 323850:SHEW_RS18545
uniprot id: A3QIZ5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.

323850:SHEW RS02145
gene id: 323850:SHEW_RS02145
uniprot id: A3Q9Z0
names: Similarity
messages: Belongs to the peptidase U62 family.

323850:SHEW RS18140
gene id: 323850:SHEW_RS18140
uniprot id: A3QIR8
names: Similarity
messages: Belongs to the RutC family.

323850:SHEW RS05220
gene id: 323850:SHEW_RS05220
uniprot id: A3QBN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaD Na(+)/H(+) (TC 2.A.62) antiporter family.
messages: Membrane

323850:SHEW RS02210
gene id: 323850:SHEW_RS02210
uniprot id: A3QA04
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

323850:SHEW RS17705
gene id: 323850:SHEW_RS17705
uniprot id: A3QIJ2
names: Cofactor
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.

323850:SHEW RS02735
gene id: 323850:SHEW_RS02735
uniprot id: A3QAA8
names: Subcellular Location Annotation
messages: Membrane

323850:SHEW RS14840
gene id: 323850:SHEW_RS14840
uniprot id: A3QGZ3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ApbE family.
messages: Cell inner membrane
messages: Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.
messages: Magnesium. Can also use manganese.

323850:SHEW RS13990
gene id: 323850:SHEW_RS13990
uniprot id: A3QGH4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Membrane
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

323850:SHEW RS06520
gene id: 323850:SHEW_RS06520
uniprot id: A3QCE0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

323850:SHEW RS18300
gene id: 323850:SHEW_RS18300
uniprot id: A3QIU9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid/polyamine transporter 2 family. Mtr/TnaB/TyrP permease subfamily.
messages: Cell inner membrane
messages: Involved in transporting aromatic amino acids across the cytoplasmic membrane.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

323850:SHEW RS00025
gene id: 323850:SHEW_RS00025
uniprot id: A3Q8S8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

323850:SHEW RS09345
gene id: 323850:SHEW_RS09345
uniprot id: A3QDX8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

323850:SHEW RS11530
gene id: 323850:SHEW_RS11530
uniprot id: A3QF43
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinylarginine dihydrolase family.
messages: Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2).
messages: Homodimer.

323850:SHEW RS08080
gene id: 323850:SHEW_RS08080
uniprot id: A3QD74
names: Function
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia.

323850:SHEW RS14955
gene id: 323850:SHEW_RS14955
uniprot id: A3QH16
names: Similarity
messages: Belongs to the UPF0438 family.

323850:SHEW RS01040
gene id: 323850:SHEW_RS01040
uniprot id: A3Q9C2
names: Similarity
messages: Belongs to the CinA family.

323850:SHEW RS09230
gene id: 323850:SHEW_RS09230
uniprot id: A3QDV5
names: Similarity
messages: Belongs to the heat shock protein 70 family.

323850:SHEW RS06660
gene id: 323850:SHEW_RS06660
uniprot id: A3QCG8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

323850:SHEW RS16330
gene id: 323850:SHEW_RS16330
uniprot id: A3QHS2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

323850:SHEW RS08310
gene id: 323850:SHEW_RS08310
uniprot id: A3QDC1
names: Similarity
messages: Belongs to the fabD family.

323850:SHEW RS01945
gene id: 323850:SHEW_RS01945
uniprot id: A3Q9U9
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

323850:SHEW RS18485
gene id: 323850:SHEW_RS18485
uniprot id: A3QIY6
names: Subcellular Location Annotation
messages: Membrane

323850:SHEW RS06685
gene id: 323850:SHEW_RS06685
uniprot id: A3QCH2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: In the C-terminal section; belongs to the transglycosylase Slt family.
messages: In the N-terminal section; belongs to the bacterial solute-binding protein 3 family.
messages: Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella.
messages: The N-terminal domain does not have lytic activity and probably modulates enzymatic activity. The C-terminal domain is the catalytic active domain.

323850:SHEW RS17940
gene id: 323850:SHEW_RS17940
uniprot id: A3QIM7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transpeptidase family. FtsI subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall at the division septum.
messages: Cell inner membrane

323850:SHEW RS14315
gene id: 323850:SHEW_RS14315
uniprot id: A3QGP0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

323850:SHEW RS03165
gene id: 323850:SHEW_RS03165
uniprot id: A3QAI9
names: Function
names: Similarity
messages: In the C-terminal section; belongs to the aldehyde dehydrogenase family.
messages: In the N-terminal section; belongs to the proline dehydrogenase family.
messages: Oxidizes proline to glutamate for use as a carbon and nitrogen source.

323850:SHEW RS09160
gene id: 323850:SHEW_RS09160
uniprot id: A3QDU1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

323850:SHEW RS03725
gene id: 323850:SHEW_RS03725
uniprot id: A3QAU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

323850:SHEW RS09500
gene id: 323850:SHEW_RS09500
uniprot id: A3QE03
names: Similarity
messages: Belongs to the glutaredoxin family. Monothiol subfamily.

323850:SHEW RS18075
gene id: 323850:SHEW_RS18075
uniprot id: A3QIQ4
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Toroid-shaped homodecamer, composed of two pentamers of five dimers.

323850:SHEW RS05025
gene id: 323850:SHEW_RS05025
uniprot id: A3QBK1
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflC subfamily.

323850:SHEW RS04065
gene id: 323850:SHEW_RS04065
uniprot id: A3QB11
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

323850:SHEW RS08040
gene id: 323850:SHEW_RS08040
uniprot id: A3QD66
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

323850:SHEW RS12620
gene id: 323850:SHEW_RS12620
uniprot id: A3QFQ7
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

323850:SHEW RS18710
gene id: 323850:SHEW_RS18710
uniprot id: A3QJ28
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP M family.
messages: Cell inner membrane
messages: Inner membrane component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.
messages: Membrane

323850:SHEW RS09895
gene id: 323850:SHEW_RS09895
uniprot id: A3QE80
names: Similarity
messages: Belongs to the dGTPase family. Type 2 subfamily.

323850:SHEW RS19190
gene id: 323850:SHEW_RS19190
uniprot id: A3QJC3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

323850:SHEW RS09075
gene id: 323850:SHEW_RS09075
uniprot id: A3QDS3
names: Function
names: Similarity
messages: Belongs to the HypA/HybF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.

323850:SHEW RS14090
gene id: 323850:SHEW_RS14090
uniprot id: A3QGJ4
names: Similarity
messages: Belongs to the UPF0178 family.

323850:SHEW RS09095
gene id: 323850:SHEW_RS09095
uniprot id: A3QDS7
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily.

323850:SHEW RS02860
gene id: 323850:SHEW_RS02860
uniprot id: A3QAD3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-to-5' exoribonuclease specific for small oligoribonucleotides.
messages: Belongs to the oligoribonuclease family.
messages: Cytoplasm

323850:SHEW RS02160
gene id: 323850:SHEW_RS02160
uniprot id: A3Q9Z3
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

323850:SHEW RS13620
gene id: 323850:SHEW_RS13620
uniprot id: A3QGA0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

323850:SHEW RS19210
gene id: 323850:SHEW_RS19210
uniprot id: A3QJC7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.
messages: Homodimer.

323850:SHEW RS17955
gene id: 323850:SHEW_RS17955
uniprot id: A3QIN0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

323850:SHEW RS15220
gene id: 323850:SHEW_RS15220
uniprot id: A3QH61
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acetylates the N-terminal alanine of ribosomal protein S18.
messages: Belongs to the acetyltransferase family. RimI subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

323850:SHEW RS13260
gene id: 323850:SHEW_RS13260
uniprot id: A3QG29
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

323850:SHEW RS03785
gene id: 323850:SHEW_RS03785
uniprot id: A3QAV9
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.

323850:SHEW RS10970
gene id: 323850:SHEW_RS10970
uniprot id: A3QET0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

323850:SHEW RS17465
gene id: 323850:SHEW_RS17465
uniprot id: A3QIE4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell inner membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

323850:SHEW RS18015
gene id: 323850:SHEW_RS18015
uniprot id: A3QIP2
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

323850:SHEW RS05710
gene id: 323850:SHEW_RS05710
uniprot id: A3QBY2
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

323850:SHEW RS04830
gene id: 323850:SHEW_RS04830
uniprot id: A3QBG2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

323850:SHEW RS07905
gene id: 323850:SHEW_RS07905
uniprot id: A3QD47
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Pal lipoprotein family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

323850:SHEW RS17695
gene id: 323850:SHEW_RS17695
uniprot id: A3QIJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.

323850:SHEW RS00925
gene id: 323850:SHEW_RS00925
uniprot id: A3Q9A2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell inner membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

323850:SHEW RS15175
gene id: 323850:SHEW_RS15175
uniprot id: A3QH52
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

323850:SHEW RS07070
gene id: 323850:SHEW_RS07070
uniprot id: A3QCP8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

323850:SHEW RS12005
gene id: 323850:SHEW_RS12005
uniprot id: A3QFD8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.
messages: Cytoplasm
messages: Homodimer.

323850:SHEW RS08000
gene id: 323850:SHEW_RS08000
uniprot id: A3QD58
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

323850:SHEW RS02720
gene id: 323850:SHEW_RS02720
uniprot id: A3QAA5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. DeaD/CsdA subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation.

323850:SHEW RS14945
gene id: 323850:SHEW_RS14945
uniprot id: A3QH14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

323850:SHEW RS05035
gene id: 323850:SHEW_RS05035
uniprot id: A3QBK3
names: Subcellular Location Annotation
messages: Cell inner membrane

323850:SHEW RS16970
gene id: 323850:SHEW_RS16970
uniprot id: A3QI47
names: Similarity
messages: Belongs to the peptidase S46 family.

323850:SHEW RS09855
gene id: 323850:SHEW_RS09855
uniprot id: A3QE72
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I fumarase family.
messages: Catalyzes the reversible hydration of fumarate to (S)-malate.
messages: Homodimer.

323850:SHEW RS04970
gene id: 323850:SHEW_RS04970
uniprot id: A3QBJ0
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

323850:SHEW RS16615
gene id: 323850:SHEW_RS16615
uniprot id: A3QHX9
names: Similarity
messages: Belongs to the GST superfamily.

323850:SHEW RS15140
gene id: 323850:SHEW_RS15140
uniprot id: A3QH45
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell inner membrane
messages: Membrane

323850:SHEW RS04505
gene id: 323850:SHEW_RS04505
uniprot id: A3QBA0
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

323850:SHEW RS07170
gene id: 323850:SHEW_RS07170
uniprot id: A3QCR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane

323850:SHEW RS16925
gene id: 323850:SHEW_RS16925
uniprot id: A3QI38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

323850:SHEW RS12380
gene id: 323850:SHEW_RS12380
uniprot id: A3QFK8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycyl radical enzyme (GRE) family. PFL subfamily.
messages: Cytoplasm
messages: Homodimer.

323850:SHEW RS16780
gene id: 323850:SHEW_RS16780
uniprot id: A3QI10
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

323850:SHEW RS17400
gene id: 323850:SHEW_RS17400
uniprot id: A3QID1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

323850:SHEW RS01240
gene id: 323850:SHEW_RS01240
uniprot id: A3Q9G2
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

323850:SHEW RS19940
gene id: 323850:SHEW_RS19940
uniprot id: A3QJR4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell inner membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.

323850:SHEW RS15035
gene id: 323850:SHEW_RS15035
uniprot id: A3QH32
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LolB family.
messages: Cell outer membrane
messages: Monomer.
messages: Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein.

323850:SHEW RS16180
gene id: 323850:SHEW_RS16180
uniprot id: A3QHP6
names: Similarity
messages: Belongs to the SfsA family.

323850:SHEW RS01265
gene id: 323850:SHEW_RS01265
uniprot id: A3Q9G7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

323850:SHEW RS15720
gene id: 323850:SHEW_RS15720
uniprot id: A3QHF6
names: Similarity
messages: Belongs to the asparagine synthetase family.

323850:SHEW RS11535
gene id: 323850:SHEW_RS11535
uniprot id: A3QF44
names: Similarity
messages: Belongs to the intimin/invasin family.

323850:SHEW RS08910
gene id: 323850:SHEW_RS08910
uniprot id: A3QDN9
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

323850:SHEW RS07290
gene id: 323850:SHEW_RS07290
uniprot id: A3QCU1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PAPS reductase family. CysD subfamily.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

323850:SHEW RS19985
gene id: 323850:SHEW_RS19985
uniprot id: A3QJS3
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
messages: O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.

323850:SHEW RS10780
gene id: 323850:SHEW_RS10780
uniprot id: A3QEP4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

323850:SHEW RS17255
gene id: 323850:SHEW_RS17255
uniprot id: A3QIA3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the multicopper oxidase family.
messages: Binds 1 Cu(+) ion.
messages: Homotrimer.
messages: Periplasm

323850:SHEW RS09650
gene id: 323850:SHEW_RS09650
uniprot id: A3QE33
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

323850:SHEW RS19710
gene id: 323850:SHEW_RS19710
uniprot id: A3QJM2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecB family.
messages: Cytoplasm
messages: Homotetramer, a dimer of dimers. One homotetramer interacts with 1 SecA dimer.
messages: One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.

323850:SHEW RS12890
gene id: 323850:SHEW_RS12890
uniprot id: A3QFW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0283 family.
messages: Cell inner membrane
messages: Membrane

323850:SHEW RS05625
gene id: 323850:SHEW_RS05625
uniprot id: A3QBW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell inner membrane
messages: Membrane

323850:SHEW RS06430
gene id: 323850:SHEW_RS06430
uniprot id: A3QCC0
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

323850:SHEW RS05895
gene id: 323850:SHEW_RS05895
uniprot id: A3QC17
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

323850:SHEW RS11270
gene id: 323850:SHEW_RS11270
uniprot id: A3QEZ1
names: Subcellular Location Annotation
messages: Membrane

323850:SHEW RS12490
gene id: 323850:SHEW_RS12490
uniprot id: A3QFN0
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.

323850:SHEW RS08500
gene id: 323850:SHEW_RS08500
uniprot id: A3QDF9
names: Similarity
messages: Belongs to the UPF0434 family.

323850:SHEW RS00735
gene id: 323850:SHEW_RS00735
uniprot id: A3Q966
names: Function
names: Similarity
messages: Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon.
messages: Belongs to the biotin--protein ligase family.

323850:SHEW RS03970
gene id: 323850:SHEW_RS03970
uniprot id: A3QAZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. tRNA (adenine-N(6)-)-methyltransferase family.
messages: Cytoplasm
messages: Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC).

323850:SHEW RS07015
gene id: 323850:SHEW_RS07015
uniprot id: A3QCN7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The M ring is integral to the inner membrane of the cell and may be connected to the flagellar rod via the S ring. The S (supramembrane ring) lies just distal to the M ring. The L and P rings lie in the outer membrane and the periplasmic space, respectively.

323850:SHEW RS16905
gene id: 323850:SHEW_RS16905
uniprot id: A3QI34
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbD subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps.

323850:SHEW RS15250
gene id: 323850:SHEW_RS15250
uniprot id: A3QH63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

323850:SHEW RS14640
gene id: 323850:SHEW_RS14640
uniprot id: A3QGV3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
messages: Cytoplasm
messages: Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.

323850:SHEW RS03600
gene id: 323850:SHEW_RS03600
uniprot id: A3QAS6
names: Subcellular Location Annotation
messages: Membrane

323850:SHEW RS09835
gene id: 323850:SHEW_RS09835
uniprot id: A3QE68
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

323850:SHEW RS05510
gene id: 323850:SHEW_RS05510
uniprot id: A3QBU2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HCP family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 hybrid [4Fe-2O-2S] cluster.
messages: Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
messages: Cytoplasm

323850:SHEW RS08410
gene id: 323850:SHEW_RS08410
uniprot id: A3QDE1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
messages: Homodimer.

323850:SHEW RS19125
gene id: 323850:SHEW_RS19125
uniprot id: A3QJB0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

323850:SHEW RS10050
gene id: 323850:SHEW_RS10050
uniprot id: A3QEA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S49 family.
messages: Cell inner membrane

323850:SHEW RS08560
gene id: 323850:SHEW_RS08560
uniprot id: A3QDH1
names: Cofactor
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cell inner membrane
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD.
messages: The heme is bound between the two transmembrane subunits.

323850:SHEW RS19255
gene id: 323850:SHEW_RS19255
uniprot id: A3QJD6
names: Function
names: Similarity
names: Subunit
messages: A GTPase-activating protein (GAP) that modifies Der/EngA GTPase function. May play a role in ribosome biogenesis.
messages: Belongs to the YihI family.
messages: Interacts with Der.

323850:SHEW RS06950
gene id: 323850:SHEW_RS06950
uniprot id: A3QCM4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Flagellum-specific muramidase which hydrolyzes the peptidoglycan layer to assemble the rod structure in the periplasmic space.
messages: In the C-terminal section; belongs to the glycosyl hydrolase 73 family.
messages: In the N-terminal section; belongs to the FlgJ family.
messages: Periplasm

323850:SHEW RS17445
gene id: 323850:SHEW_RS17445
uniprot id: A3QIE0
names: Similarity
messages: Belongs to the arginase family.

323850:SHEW RS06415
gene id: 323850:SHEW_RS06415
uniprot id: A3QCB7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

323850:SHEW RS04795
gene id: 323850:SHEW_RS04795
uniprot id: A3QBF5
names: Cofactor
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

323850:SHEW RS17090
gene id: 323850:SHEW_RS17090
uniprot id: A3QI71
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MlaE permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the ABC transporter complex MlaFEDB, which is involved in a phospholipid transport pathway that maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (MlaF), two transmembrane proteins (MlaE), two cytoplasmic solute-binding proteins (MlaB) and six periplasmic solute-binding proteins (MlaD).

323850:SHEW RS01630
gene id: 323850:SHEW_RS01630
uniprot id: A3Q9N6
names: Subcellular Location Annotation
messages: Membrane

323850:SHEW RS17065
gene id: 323850:SHEW_RS17065
uniprot id: A3QI66
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm

323850:SHEW RS10690
gene id: 323850:SHEW_RS10690
uniprot id: A3QEN0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

323850:SHEW RS17990
gene id: 323850:SHEW_RS17990
uniprot id: A3QIN7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

323850:SHEW RS08105
gene id: 323850:SHEW_RS08105
uniprot id: A3QD79
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm

323850:SHEW RS16195
gene id: 323850:SHEW_RS16195
uniprot id: A3QHP9
names: Function
names: Similarity
messages: Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

323850:SHEW RS18715
gene id: 323850:SHEW_RS18715
uniprot id: A3QJ29
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP L family.
messages: Cell inner membrane
messages: Inner membrane component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.
messages: Membrane

323850:SHEW RS17930
gene id: 323850:SHEW_RS17930
uniprot id: A3QIM5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

323850:SHEW RS14855
gene id: 323850:SHEW_RS14855
uniprot id: A3QGZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

323850:SHEW RS12930
gene id: 323850:SHEW_RS12930
uniprot id: A3QFW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

323850:SHEW RS17770
gene id: 323850:SHEW_RS17770
uniprot id: A3QIK5
names: Subcellular Location Annotation
messages: Membrane

323850:SHEW RS06485
gene id: 323850:SHEW_RS06485
uniprot id: A3QCD2
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

323850:SHEW RS18000
gene id: 323850:SHEW_RS18000
uniprot id: A3QIN9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

323850:SHEW RS16255
gene id: 323850:SHEW_RS16255
uniprot id: A3QHR0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm
messages: Purine salvage pathway enzyme which catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of hypoxanthine to yield IMP (inosine 5'-monophosphate). To a lesser extent, can also act on guanine leading to GMP, but shows a highly less efficient activity with xanthine.

323850:SHEW RS00895
gene id: 323850:SHEW_RS00895
uniprot id: A3Q995
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

323850:SHEW RS01625
gene id: 323850:SHEW_RS01625
uniprot id: A3Q9N5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
messages: Cell inner membrane

323850:SHEW RS11415
gene id: 323850:SHEW_RS11415
uniprot id: A3QF20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

323850:SHEW RS16880
gene id: 323850:SHEW_RS16880
uniprot id: A3QI29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TPMT family.
messages: Cytoplasm

323850:SHEW RS00610
gene id: 323850:SHEW_RS00610
uniprot id: A3Q946
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

323850:SHEW RS10465
gene id: 323850:SHEW_RS10465
uniprot id: A3QEI9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell inner membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.

323850:SHEW RS11410
gene id: 323850:SHEW_RS11410
uniprot id: A3QF19
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

323850:SHEW RS08120
gene id: 323850:SHEW_RS08120
uniprot id: A3QD82
names: Cofactor
names: Similarity
messages: Belongs to the monomeric-type IDH family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

323850:SHEW RS13380
gene id: 323850:SHEW_RS13380
uniprot id: A3QG53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone-like protein H-NS family.
messages: nucleoid

323850:SHEW RS18345
gene id: 323850:SHEW_RS18345
uniprot id: A3QIV8
names: Cofactor
names: PTM
names: Similarity
messages: Belongs to the NapC/NirT/NrfH family.
messages: Binds 4 heme groups per subunit.

323850:SHEW RS19115
gene id: 323850:SHEW_RS19115
uniprot id: A3QJA8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

323850:SHEW RS14685
gene id: 323850:SHEW_RS14685
uniprot id: A3QGW2
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

323850:SHEW RS01755
gene id: 323850:SHEW_RS01755
uniprot id: A3Q9R2
names: Similarity
messages: Belongs to the thioredoxin family.

323850:SHEW RS06775
gene id: 323850:SHEW_RS06775
uniprot id: A3QCJ0
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

323850:SHEW RS19670
gene id: 323850:SHEW_RS19670
uniprot id: A3QJL5
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

323850:SHEW RS10505
gene id: 323850:SHEW_RS10505
uniprot id: A3QEJ7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

323850:SHEW RS11810
gene id: 323850:SHEW_RS11810
uniprot id: A3QF99
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.

323850:SHEW RS11755
gene id: 323850:SHEW_RS11755
uniprot id: A3QF88
names: Similarity
messages: Belongs to the peptidase S33 family.

323850:SHEW RS01915
gene id: 323850:SHEW_RS01915
uniprot id: A3Q9U3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase bacterial subunit 4 family.
messages: Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.
messages: Heterooctamer of two A chains, two B chains, two C chains and two D chains.
messages: Membrane

323850:SHEW RS18685
gene id: 323850:SHEW_RS18685
uniprot id: A3QJ23
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division. Important for assembly or stability of the septal ring.

323850:SHEW RS08295
gene id: 323850:SHEW_RS08295
uniprot id: A3QDB7
names: Function
names: Similarity
messages: Belongs to the DUF177 domain family.
messages: Plays a role in synthesis, processing and/or stability of 23S rRNA.

323850:SHEW RS13335
gene id: 323850:SHEW_RS13335
uniprot id: A3QG44
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

323850:SHEW RS03155
gene id: 323850:SHEW_RS03155
uniprot id: A3QAI7
names: Subcellular Location Annotation
messages: Membrane

323850:SHEW RS00880
gene id: 323850:SHEW_RS00880
uniprot id: A3Q992
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

323850:SHEW RS04625
gene id: 323850:SHEW_RS04625
uniprot id: A3QBC3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

323850:SHEW RS05965
gene id: 323850:SHEW_RS05965
uniprot id: A3QC31
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

323850:SHEW RS10335
gene id: 323850:SHEW_RS10335
uniprot id: A3QEG7
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

323850:SHEW RS03745
gene id: 323850:SHEW_RS03745
uniprot id: A3QAV2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Homodimer.

323850:SHEW RS00110
gene id: 323850:SHEW_RS00110
uniprot id: A3Q8U5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M24B family. Bacterial-type prolidase subfamily.
messages: Binds 2 manganese ions per subunit.
messages: Splits dipeptides with a prolyl residue in the C-terminal position.

323850:SHEW RS18560
gene id: 323850:SHEW_RS18560
uniprot id: A3QIZ8
names: Similarity
messages: Belongs to the peptidase M16 family.

323850:SHEW RS15025
gene id: 323850:SHEW_RS15025
uniprot id: A3QH30
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

323850:SHEW RS07835
gene id: 323850:SHEW_RS07835
uniprot id: A3QD33
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

323850:SHEW RS14390
gene id: 323850:SHEW_RS14390
uniprot id: A3QGQ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase U32 family. UbiU subfamily.
messages: Forms an heterodimer with UbiV.
messages: Required for O(2)-independent ubiquinone (coenzyme Q) biosynthesis. Together with UbiV, is essential for the C6-hydroxylation reaction in the oxygen-independent ubiquinone biosynthesis pathway.

323850:SHEW RS02475
gene id: 323850:SHEW_RS02475
uniprot id: A3QA56
names: Subcellular Location Annotation
messages: Cell outer membrane

323850:SHEW RS05995
gene id: 323850:SHEW_RS05995
uniprot id: A3QC37
names: Subcellular Location Annotation
messages: Cytoplasm

323850:SHEW RS01980
gene id: 323850:SHEW_RS01980
uniprot id: A3Q9V7
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

323850:SHEW RS15725
gene id: 323850:SHEW_RS15725
uniprot id: A3QHF7
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

323850:SHEW RS06150
gene id: 323850:SHEW_RS06150
uniprot id: A3QC68
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

323850:SHEW RS05740
gene id: 323850:SHEW_RS05740
uniprot id: A3QBY8
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

323850:SHEW RS16605
gene id: 323850:SHEW_RS16605
uniprot id: A3QHX7
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NapB family.
messages: Binds 2 heme C groups per subunit.
messages: Component of the periplasmic nitrate reductase NapAB complex composed of NapA and NapB.
messages: Electron transfer subunit of the periplasmic nitrate reductase complex NapAB.
messages: Periplasm

323850:SHEW RS04535
gene id: 323850:SHEW_RS04535
uniprot id: A3QBA6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptD family.
messages: Cell outer membrane
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptE and LptA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.

323850:SHEW RS13650
gene id: 323850:SHEW_RS13650
uniprot id: A3QGA6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family.
messages: Cytoplasm
messages: Homotrimer.

323850:SHEW RS03990
gene id: 323850:SHEW_RS03990
uniprot id: A3QAZ6
names: Similarity
messages: Belongs to the RecJ family.

323850:SHEW RS04480
gene id: 323850:SHEW_RS04480
uniprot id: A3QB95
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

323850:SHEW RS05630
gene id: 323850:SHEW_RS05630
uniprot id: A3QBW6
names: Similarity
messages: Belongs to the UPF0246 family.

323850:SHEW RS15500
gene id: 323850:SHEW_RS15500
uniprot id: A3QHB2
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

323850:SHEW RS07660
gene id: 323850:SHEW_RS07660
uniprot id: A3QCZ8
names: Similarity
messages: Belongs to the DNA photolyase class-1 family.
messages: Belongs to the DNA photolyase family.

323850:SHEW RS00085
gene id: 323850:SHEW_RS00085
uniprot id: A3Q8U0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfur carrier protein TusA family.
messages: Cytoplasm
messages: Sulfur carrier protein which probably makes part of a sulfur-relay system.

323850:SHEW RS06340
gene id: 323850:SHEW_RS06340
uniprot id: A3QCA2
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

323850:SHEW RS00850
gene id: 323850:SHEW_RS00850
uniprot id: A3Q986
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

323850:SHEW RS02080
gene id: 323850:SHEW_RS02080
uniprot id: A3Q9X7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

323850:SHEW RS05605
gene id: 323850:SHEW_RS05605
uniprot id: A3QBW1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

323850:SHEW RS13790
gene id: 323850:SHEW_RS13790
uniprot id: A3QGD3
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

323850:SHEW RS08385
gene id: 323850:SHEW_RS08385
uniprot id: A3QDD6
names: Similarity
messages: Belongs to the UPF0502 family.

323850:SHEW RS03880
gene id: 323850:SHEW_RS03880
uniprot id: A3QAX8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

323850:SHEW RS06095
gene id: 323850:SHEW_RS06095
uniprot id: A3QC57
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.

323850:SHEW RS00760
gene id: 323850:SHEW_RS00760
uniprot id: A3Q968
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

323850:SHEW RS04910
gene id: 323850:SHEW_RS04910
uniprot id: A3QBH8
names: Similarity
messages: Belongs to the peptidase M24B family.

323850:SHEW RS18290
gene id: 323850:SHEW_RS18290
uniprot id: A3QIU7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
messages: Belongs to the azoreductase type 1 family.
messages: Binds 1 FMN per subunit.
messages: Homodimer.
messages: Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones.

323850:SHEW RS14430
gene id: 323850:SHEW_RS14430
uniprot id: A3QGR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Membrane

323850:SHEW RS00105
gene id: 323850:SHEW_RS00105
uniprot id: A3Q8U4
names: Function
names: Similarity
names: Subunit
messages: Heterotetramer of two alpha chains (FadB) and two beta chains (FadA).
messages: In the C-terminal section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family.
messages: In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.
messages: Involved in the aerobic and anaerobic degradation of long-chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate.

323850:SHEW RS13630
gene id: 323850:SHEW_RS13630
uniprot id: A3QGA2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

323850:SHEW RS11425
gene id: 323850:SHEW_RS11425
uniprot id: A3QF22
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the PRA-PH family.
messages: In the N-terminal section; belongs to the PRA-CH family.

323850:SHEW RS17115
gene id: 323850:SHEW_RS17115
uniprot id: A3QI76
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptC family.
messages: Cell inner membrane
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptA and the LptBFG transporter complex.
messages: Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA.
messages: Required for the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.

323850:SHEW RS09655
gene id: 323850:SHEW_RS09655
uniprot id: A3QE34
names: Subcellular Location Annotation
messages: Cytoplasm

323850:SHEW RS14915
gene id: 323850:SHEW_RS14915
uniprot id: A3QH08
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

323850:SHEW RS18770
gene id: 323850:SHEW_RS18770
uniprot id: A3QJ40
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSP33 family.
messages: Cytoplasm
messages: Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.
messages: Under oxidizing conditions two disulfide bonds are formed involving the reactive cysteines. Under reducing conditions zinc is bound to the reactive cysteines and the protein is inactive.

323850:SHEW RS11900
gene id: 323850:SHEW_RS11900
uniprot id: A3QFB7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the type IA topoisomerase family.
messages: Binds two Mg(2+) per subunit.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

323850:SHEW RS11800
gene id: 323850:SHEW_RS11800
uniprot id: A3QF97
names: Subcellular Location Annotation
messages: Periplasm

323850:SHEW RS19665
gene id: 323850:SHEW_RS19665
uniprot id: A3QJL4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

323850:SHEW RS16040
gene id: 323850:SHEW_RS16040
uniprot id: A3QHL9
names: Similarity
messages: Belongs to the universal stress protein A family.

323850:SHEW RS05450
gene id: 323850:SHEW_RS05450
uniprot id: A3QBT0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.

323850:SHEW RS02675
gene id: 323850:SHEW_RS02675
uniprot id: A3QA96
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

323850:SHEW RS16495
gene id: 323850:SHEW_RS16495
uniprot id: A3QHV5
names: Function
names: Similarity
messages: Belongs to the peptidase S46 family.
messages: Catalyzes the removal of dipeptides from the N-terminus of oligopeptides.

323850:SHEW RS07265
gene id: 323850:SHEW_RS07265
uniprot id: A3QCT7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. WecA subfamily.
messages: Catalyzes the transfer of the GlcNAc-1-phosphate moiety from UDP-GlcNAc onto the carrier lipid undecaprenyl phosphate (C55-P), yielding GlcNAc-pyrophosphoryl-undecaprenyl (GlcNAc-PP-C55).
messages: Cell inner membrane
messages: Membrane

323850:SHEW RS06630
gene id: 323850:SHEW_RS06630
uniprot id: A3QCG2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

323850:SHEW RS15205
gene id: 323850:SHEW_RS15205
uniprot id: A3QH58
names: Similarity
messages: Belongs to the UPF0250 family.

323850:SHEW RS10590
gene id: 323850:SHEW_RS10590
uniprot id: A3QEL3
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

323850:SHEW RS14260
gene id: 323850:SHEW_RS14260
uniprot id: A3QGM9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily.
messages: Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA.
messages: Cytoplasm
messages: Monomer.

323850:SHEW RS17730
gene id: 323850:SHEW_RS17730
uniprot id: A3QIJ7
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

323850:SHEW RS19945
gene id: 323850:SHEW_RS19945
uniprot id: A3QJR5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase C chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.

323850:SHEW RS10775
gene id: 323850:SHEW_RS10775
uniprot id: A3QEP3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

323850:SHEW RS08300
gene id: 323850:SHEW_RS08300
uniprot id: A3QDB9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

323850:SHEW RS00775
gene id: 323850:SHEW_RS00775
uniprot id: A3Q971
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

323850:SHEW RS15900
gene id: 323850:SHEW_RS15900
uniprot id: A3QHJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

323850:SHEW RS19795
gene id: 323850:SHEW_RS19795
uniprot id: A3QJN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

323850:SHEW RS15850
gene id: 323850:SHEW_RS15850
uniprot id: A3QHI2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

323850:SHEW RS14865
gene id: 323850:SHEW_RS14865
uniprot id: A3QGZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell inner membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

323850:SHEW RS02800
gene id: 323850:SHEW_RS02800
uniprot id: A3QAC1
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase class-III family.

323850:SHEW RS18135
gene id: 323850:SHEW_RS18135
uniprot id: A3QIR7
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

323850:SHEW RS07110
gene id: 323850:SHEW_RS07110
uniprot id: A3QCQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CheZ family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P).

323850:SHEW RS09915
gene id: 323850:SHEW_RS09915
uniprot id: A3QE84
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 104 family.
messages: Protein-arginine rhamnosyltransferase that catalyzes the transfer of a single rhamnose to elongation factor P (EF-P) on 'Lys-32', a modification required for EF-P-dependent rescue of polyproline stalled ribosomes.

323850:SHEW RS06675
gene id: 323850:SHEW_RS06675
uniprot id: A3QCH1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

323850:SHEW RS05795
gene id: 323850:SHEW_RS05795
uniprot id: A3QBZ7
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

323850:SHEW RS05670
gene id: 323850:SHEW_RS05670
uniprot id: A3QBX4
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

323850:SHEW RS06250
gene id: 323850:SHEW_RS06250
uniprot id: A3QC89
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

323850:SHEW RS12995
gene id: 323850:SHEW_RS12995
uniprot id: A3QFX8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

323850:SHEW RS11975
gene id: 323850:SHEW_RS11975
uniprot id: A3QFD2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HscB family.
messages: Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA.
messages: Interacts with HscA and stimulates its ATPase activity.

323850:SHEW RS14235
gene id: 323850:SHEW_RS14235
uniprot id: A3QGM4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Xni family.
messages: Binds 1 K(+) per subunit. The potassium ion strongly increases the affinity for DNA.
messages: Binds 2 Mg(2+) per subunit. Only one magnesium ion has a direct interaction with the protein, the other interactions are indirect.
messages: Has flap endonuclease activity. During DNA replication, flap endonucleases cleave the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment.

323850:SHEW RS14520
gene id: 323850:SHEW_RS14520
uniprot id: A3QGT1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphopentomutase family.
messages: Binds 1 or 2 manganese ions.
messages: Cytoplasm
messages: Phosphotransfer between the C1 and C5 carbon atoms of pentose.

323850:SHEW RS09080
gene id: 323850:SHEW_RS09080
uniprot id: A3QDS4
names: Similarity
messages: Belongs to the HypE family.

323850:SHEW RS05635
gene id: 323850:SHEW_RS05635
uniprot id: A3QBW7
names: Subcellular Location Annotation
messages: Endoplasmic reticulum
messages: Golgi apparatus
messages: Lysosome
messages: Secreted

323850:SHEW RS01180
gene id: 323850:SHEW_RS01180
uniprot id: A3Q9F0
names: Similarity
messages: Belongs to the UPF0102 family.

323850:SHEW RS05195
gene id: 323850:SHEW_RS05195
uniprot id: A3QBM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YkuD family.
messages: Periplasm

323850:SHEW RS09950
gene id: 323850:SHEW_RS09950
uniprot id: A3QE91
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

323850:SHEW RS05365
gene id: 323850:SHEW_RS05365
uniprot id: A3QBR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

323850:SHEW RS06930
gene id: 323850:SHEW_RS06930
uniprot id: A3QCM0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of five rings (E,L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

323850:SHEW RS14785
gene id: 323850:SHEW_RS14785
uniprot id: A3QGY2
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.

323850:SHEW RS14010
gene id: 323850:SHEW_RS14010
uniprot id: A3QGH8
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

323850:SHEW RS15280
gene id: 323850:SHEW_RS15280
uniprot id: A3QH69
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamD family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

323850:SHEW RS04620
gene id: 323850:SHEW_RS04620
uniprot id: A3QBC2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

323850:SHEW RS00995
gene id: 323850:SHEW_RS00995
uniprot id: A3Q9B7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
messages: Cell inner membrane
messages: Membrane

323850:SHEW RS06055
gene id: 323850:SHEW_RS06055
uniprot id: A3QC49
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

323850:SHEW RS04460
gene id: 323850:SHEW_RS04460
uniprot id: A3QB91
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LDH/MDH superfamily. MDH type 1 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.
messages: Homodimer.

323850:SHEW RS19095
gene id: 323850:SHEW_RS19095
uniprot id: A3QJA4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: Monomer.
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

323850:SHEW RS14665
gene id: 323850:SHEW_RS14665
uniprot id: A3QGV8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

323850:SHEW RS19970
gene id: 323850:SHEW_RS19970
uniprot id: A3QJS0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.

323850:SHEW RS05205
gene id: 323850:SHEW_RS05205
uniprot id: A3QBN1
names: Cofactor
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A single active site specifically recognizes both ATP and CTP and is responsible for their addition.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 1 subfamily.
messages: Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases.
messages: Comprises two domains: an N-terminal domain containing the nucleotidyltransferase activity and a C-terminal HD domain associated with both phosphodiesterase and phosphatase activities.
messages: Magnesium is required for nucleotidyltransferase activity.
messages: Monomer. Can also form homodimers and oligomers.
messages: Nickel for phosphatase activity.

323850:SHEW RS00785
gene id: 323850:SHEW_RS00785
uniprot id: A3Q973
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

323850:SHEW RS18835
gene id: 323850:SHEW_RS18835
uniprot id: A3QJ53
names: Similarity
messages: Belongs to the TPP enzyme family.

323850:SHEW RS17780
gene id: 323850:SHEW_RS17780
uniprot id: A3QIK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell inner membrane
messages: Membrane

323850:SHEW RS17555
gene id: 323850:SHEW_RS17555
uniprot id: A3QIG2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.
messages: Membrane

323850:SHEW RS07175
gene id: 323850:SHEW_RS07175
uniprot id: A3QCR9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RfaH family.
messages: Enhances distal genes transcription elongation in a specialized subset of operons that encode extracytoplasmic components.
messages: Interacts with both the nontemplate DNA and the RNA polymerase (RNAP).

323850:SHEW RS11060
gene id: 323850:SHEW_RS11060
uniprot id: A3QEU8
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA.
messages: Belongs to the helicase family. UvrD subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding. Interacts with RecA.
messages: The C-terminal domain has nuclease activity and interacts with RecD. It interacts with RecA, facilitating its loading onto ssDNA.
messages: The N-terminal DNA-binding domain is a ssDNA-dependent ATPase and has ATP-dependent 3'-5' helicase function. This domain interacts with RecC.

323850:SHEW RS01705
gene id: 323850:SHEW_RS01705
uniprot id: A3Q9Q2
names: Subcellular Location Annotation
messages: Cytoplasm

323850:SHEW RS17645
gene id: 323850:SHEW_RS17645
uniprot id: A3QII0
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

323850:SHEW RS02155
gene id: 323850:SHEW_RS02155
uniprot id: A3Q9Z2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Cell membrane
messages: Membrane

323850:SHEW RS16185
gene id: 323850:SHEW_RS16185
uniprot id: A3QHP7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DksA family.
messages: Cytoplasm
messages: Interacts directly with the RNA polymerase.
messages: Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression.

323850:SHEW RS14985
gene id: 323850:SHEW_RS14985
uniprot id: A3QH22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

323850:SHEW RS04525
gene id: 323850:SHEW_RS04525
uniprot id: A3QBA4
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PdxA family.
messages: Binds 1 divalent metal cation per subunit. Can use ions such as Zn(2+), Mg(2+) or Co(2+).
messages: Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).
messages: Cytoplasm
messages: Homodimer.
messages: The active site is located at the dimer interface.

323850:SHEW RS01680
gene id: 323850:SHEW_RS01680
uniprot id: A3Q9P7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.

323850:SHEW RS06240
gene id: 323850:SHEW_RS06240
uniprot id: A3QC87
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

323850:SHEW RS05295
gene id: 323850:SHEW_RS05295
uniprot id: A3QBP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Membrane

323850:SHEW RS11540
gene id: 323850:SHEW_RS11540
uniprot id: A3QF45
names: Subcellular Location Annotation
messages: Membrane

323850:SHEW RS00890
gene id: 323850:SHEW_RS00890
uniprot id: A3Q994
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

323850:SHEW RS02400
gene id: 323850:SHEW_RS02400
uniprot id: A3QA41
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

323850:SHEW RS16380
gene id: 323850:SHEW_RS16380
uniprot id: A3QHT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

323850:SHEW RS06895
gene id: 323850:SHEW_RS06895
uniprot id: A3QCL3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FlgA family.
messages: Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly.
messages: Periplasm

323850:SHEW RS17110
gene id: 323850:SHEW_RS17110
uniprot id: A3QI75
names: Function
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate.
messages: Homotetramer.

323850:SHEW RS17105
gene id: 323850:SHEW_RS17105
uniprot id: A3QI74
names: Similarity
messages: Belongs to the SIS family. GutQ/KpsF subfamily.

323850:SHEW RS19680
gene id: 323850:SHEW_RS19680
uniprot id: A3QJL6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

323850:SHEW RS05370
gene id: 323850:SHEW_RS05370
uniprot id: A3QBR4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

323850:SHEW RS07630
gene id: 323850:SHEW_RS07630
uniprot id: A3QCZ2
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.

323850:SHEW RS12400
gene id: 323850:SHEW_RS12400
uniprot id: A3QFL2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Homohexamer.
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the CobB/CobQ family.
messages: Involved in acetate metabolism.
messages: The N-terminal region seems to be important for proper quaternary structure. The C-terminal region contains the substrate-binding site.

323850:SHEW RS05410
gene id: 323850:SHEW_RS05410
uniprot id: A3QBS2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E.
messages: Belongs to the RseA family.
messages: Cell inner membrane
messages: Interacts 1:1 with ECF RNA polymerase sigma-E (RpoE); this inhibits the interaction of sigma-E with the RNA polymerase catalytic core and leads to a decreased expression of sigma-E-regulated genes. Interacts with RseB.

323850:SHEW RS09980
gene id: 323850:SHEW_RS09980
uniprot id: A3QE97
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

323850:SHEW RS02170
gene id: 323850:SHEW_RS02170
uniprot id: A3Q9Z5
names: Subcellular Location Annotation
messages: Membrane

323850:SHEW RS08270
gene id: 323850:SHEW_RS08270
uniprot id: A3QDB2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase E/G family. RNase E subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per homotetramer.
messages: Cell inner membrane
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation. Within the RNA degradosome, RNase E assembles into a homotetramer formed by a dimer of dimers.
messages: Cytoplasm
messages: Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs.

323850:SHEW RS00270
gene id: 323850:SHEW_RS00270
uniprot id: A3Q8X8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.

323850:SHEW RS02460
gene id: 323850:SHEW_RS02460
uniprot id: A3QA53
names: Similarity
messages: Belongs to the HipA Ser/Thr kinase family.

323850:SHEW RS12140
gene id: 323850:SHEW_RS12140
uniprot id: A3QFG5
names: Similarity
messages: Belongs to the phosphate/phosphite/phosphonate binding protein family.

323850:SHEW RS07360
gene id: 323850:SHEW_RS07360
uniprot id: A3QCV5
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

323850:SHEW RS14205
gene id: 323850:SHEW_RS14205
uniprot id: A3QGL8
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

323850:SHEW RS14505
gene id: 323850:SHEW_RS14505
uniprot id: A3QGS8
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

323850:SHEW RS00060
gene id: 323850:SHEW_RS00060
uniprot id: A3Q8T5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

323850:SHEW RS10995
gene id: 323850:SHEW_RS10995
uniprot id: A3QET5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class II aldolase/RraA-like family.
messages: Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions.
messages: Homotrimer.

323850:SHEW RS17505
gene id: 323850:SHEW_RS17505
uniprot id: A3QIF2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family.
messages: Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
messages: Cell inner membrane

323850:SHEW RS09150
gene id: 323850:SHEW_RS09150
uniprot id: A3QDT9
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NapB family.
messages: Binds 2 heme C groups per subunit.
messages: Component of the periplasmic nitrate reductase NapAB complex composed of NapA and NapB.
messages: Electron transfer subunit of the periplasmic nitrate reductase complex NapAB.
messages: Periplasm

323850:SHEW RS10475
gene id: 323850:SHEW_RS10475
uniprot id: A3QEJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LolA family.
messages: Monomer.
messages: Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).
messages: Periplasm

323850:SHEW RS09565
gene id: 323850:SHEW_RS09565
uniprot id: A3QE16
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

323850:SHEW RS08795
gene id: 323850:SHEW_RS08795
uniprot id: A3QDL6
names: Subcellular Location Annotation
messages: Cytoplasm

323850:SHEW RS08645
gene id: 323850:SHEW_RS08645
uniprot id: A3QDI8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

323850:SHEW RS01245
gene id: 323850:SHEW_RS01245
uniprot id: A3Q9G3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the formate dehydrogenase gamma subunit family.
messages: Membrane

323850:SHEW RS13560
gene id: 323850:SHEW_RS13560
uniprot id: A3QG88
names: Subcellular Location Annotation
messages: Cytoplasm

323850:SHEW RS10750
gene id: 323850:SHEW_RS10750
uniprot id: A3QEN8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RnfG family.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

323850:SHEW RS12240
gene id: 323850:SHEW_RS12240
uniprot id: A3QFI0
names: Function
names: Similarity
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).

323850:SHEW RS01720
gene id: 323850:SHEW_RS01720
uniprot id: A3Q9Q5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

323850:SHEW RS02975
gene id: 323850:SHEW_RS02975
uniprot id: A3QAF2
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

323850:SHEW RS07055
gene id: 323850:SHEW_RS07055
uniprot id: A3QCP5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliN/MopA/SpaO family.
messages: Cell membrane
messages: FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

323850:SHEW RS13365
gene id: 323850:SHEW_RS13365
uniprot id: A3QG50
names: Subcellular Location Annotation
messages: Membrane

323850:SHEW RS01505
gene id: 323850:SHEW_RS01505
uniprot id: A3Q9L5
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

323850:SHEW RS17435
gene id: 323850:SHEW_RS17435
uniprot id: A3QID8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RraA family.
messages: Cytoplasm
messages: Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome.
messages: Homotrimer. Binds to both RNA-binding sites in the C-terminal region of Rne and to RhlB.

323850:SHEW RS19245
gene id: 323850:SHEW_RS19245
uniprot id: A3QJD4
names: PTM
messages: Binds 2 heme c groups covalently per subunit.

323850:SHEW RS16060
gene id: 323850:SHEW_RS16060
uniprot id: A3QHM3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

323850:SHEW RS04205
gene id: 323850:SHEW_RS04205
uniprot id: A3QB39
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
messages: Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
messages: Homohexamer.

323850:SHEW RS05455
gene id: 323850:SHEW_RS05455
uniprot id: A3QBT1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

323850:SHEW RS03680
gene id: 323850:SHEW_RS03680
uniprot id: A3QAT9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell inner membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

323850:SHEW RS15960
gene id: 323850:SHEW_RS15960
uniprot id: A3QHK3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the calycin superfamily. Lipocalin family.
messages: Cell outer membrane
messages: Homodimer.
messages: Involved in the storage or transport of lipids necessary for membrane maintenance under stressful conditions. Displays a binding preference for lysophospholipids.

323850:SHEW RS07555
gene id: 323850:SHEW_RS07555
uniprot id: A3QCX9
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

323850:SHEW RS18745
gene id: 323850:SHEW_RS18745
uniprot id: A3QJ35
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell inner membrane
messages: Component of the type II secretion system inner membrane complex required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.
messages: Membrane

323850:SHEW RS14355
gene id: 323850:SHEW_RS14355
uniprot id: A3QGP8
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

323850:SHEW RS06665
gene id: 323850:SHEW_RS06665
uniprot id: A3QCG9
names: Activity Regulation
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

323850:SHEW RS08245
gene id: 323850:SHEW_RS08245
uniprot id: A3QDA7
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

323850:SHEW RS04470
gene id: 323850:SHEW_RS04470
uniprot id: A3QB93
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

323850:SHEW RS10940
gene id: 323850:SHEW_RS10940
uniprot id: A3QES6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

323850:SHEW RS10430
gene id: 323850:SHEW_RS10430
uniprot id: A3QEI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

323850:SHEW RS17450
gene id: 323850:SHEW_RS17450
uniprot id: A3QIE1
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).

323850:SHEW RS15185
gene id: 323850:SHEW_RS15185
uniprot id: A3QH54
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. MrdB/RodA subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell wall elongation.

323850:SHEW RS06945
gene id: 323850:SHEW_RS06945
uniprot id: A3QCM3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgI family.
messages: Periplasm
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

323850:SHEW RS04025
gene id: 323850:SHEW_RS04025
uniprot id: A3QB03
names: Similarity
messages: Belongs to the aspartokinase family.

323850:SHEW RS07780
gene id: 323850:SHEW_RS07780
uniprot id: A3QD22
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

323850:SHEW RS08195
gene id: 323850:SHEW_RS08195
uniprot id: A3QD97
names: Function
names: Similarity
messages: Belongs to the transglycosylase MltG family.
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

323850:SHEW RS14525
gene id: 323850:SHEW_RS14525
uniprot id: A3QGT2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Homodimer.
messages: The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis.

323850:SHEW RS02730
gene id: 323850:SHEW_RS02730
uniprot id: A3QAA7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

323850:SHEW RS03545
gene id: 323850:SHEW_RS03545
uniprot id: A3QAR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

323850:SHEW RS19390
gene id: 323850:SHEW_RS19390
uniprot id: A3QJF9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. METTL16/RlmF family.
messages: Cytoplasm
messages: Specifically methylates the adenine in position 1618 of 23S rRNA.

323850:SHEW RS07375
gene id: 323850:SHEW_RS07375
uniprot id: A3QCV8
names: Similarity
messages: Belongs to the GST superfamily. Zeta family.

323850:SHEW RS06215
gene id: 323850:SHEW_RS06215
uniprot id: A3QC82
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

323850:SHEW RS08170
gene id: 323850:SHEW_RS08170
uniprot id: A3QD92
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.

323850:SHEW RS06235
gene id: 323850:SHEW_RS06235
uniprot id: A3QC86
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

323850:SHEW RS16795
gene id: 323850:SHEW_RS16795
uniprot id: A3QI13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

323850:SHEW RS09085
gene id: 323850:SHEW_RS09085
uniprot id: A3QDS5
names: Similarity
messages: Belongs to the HypD family.

323850:SHEW RS08580
gene id: 323850:SHEW_RS08580
uniprot id: A3QDH5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

323850:SHEW RS05615
gene id: 323850:SHEW_RS05615
uniprot id: A3QBW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane OOP (TC 1.B.6) superfamily. OmpA family.
messages: Cell outer membrane
messages: Membrane

323850:SHEW RS06910
gene id: 323850:SHEW_RS06910
uniprot id: A3QCL6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

323850:SHEW RS08900
gene id: 323850:SHEW_RS08900
uniprot id: A3QDN7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.

323850:SHEW RS20160
gene id: 323850:SHEW_RS20160
uniprot id: A3QHB4
names: Similarity
messages: Belongs to the peptidase A1 family.

323850:SHEW RS16205
gene id: 323850:SHEW_RS16205
uniprot id: A3QHQ1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

323850:SHEW RS16825
gene id: 323850:SHEW_RS16825
uniprot id: A3QI18
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20B family.
messages: Binds 2 Zn(2+) ions per subunit.

323850:SHEW RS18760
gene id: 323850:SHEW_RS18760
uniprot id: A3QJ38
names: Similarity
messages: Belongs to the GSP C family.

323850:SHEW RS19240
gene id: 323850:SHEW_RS19240
uniprot id: A3QJD3
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

323850:SHEW RS01005
gene id: 323850:SHEW_RS01005
uniprot id: A3Q9B9
names: Function
names: Similarity
messages: Belongs to the CcmH/CycL/Ccl2/NrfF family.
messages: Possible subunit of a heme lyase.

323850:SHEW RS13635
gene id: 323850:SHEW_RS13635
uniprot id: A3QGA3
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

323850:SHEW RS15110
gene id: 323850:SHEW_RS15110
uniprot id: A3QH39
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

323850:SHEW RS07035
gene id: 323850:SHEW_RS07035
uniprot id: A3QCP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliJ family.
messages: Cell membrane
messages: Membrane

323850:SHEW RS05015
gene id: 323850:SHEW_RS05015
uniprot id: A3QBJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

323850:SHEW RS16875
gene id: 323850:SHEW_RS16875
uniprot id: A3QI28
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

323850:SHEW RS19185
gene id: 323850:SHEW_RS19185
uniprot id: A3QJC2
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

323850:SHEW RS10120
gene id: 323850:SHEW_RS10120
uniprot id: A3QEC3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

323850:SHEW RS17910
gene id: 323850:SHEW_RS17910
uniprot id: A3QIM1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell inner membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).

323850:SHEW RS04395
gene id: 323850:SHEW_RS04395
uniprot id: A3QB77
names: Subcellular Location Annotation
messages: Membrane

323850:SHEW RS10840
gene id: 323850:SHEW_RS10840
uniprot id: A3QEQ6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

323850:SHEW RS13625
gene id: 323850:SHEW_RS13625
uniprot id: A3QGA1
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by GTP. Inhibited by UTP.
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.

323850:SHEW RS12965
gene id: 323850:SHEW_RS12965
uniprot id: A3QFX5
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

323850:SHEW RS14620
gene id: 323850:SHEW_RS14620
uniprot id: A3QGU9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

323850:SHEW RS09910
gene id: 323850:SHEW_RS09910
uniprot id: A3QE83
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

323850:SHEW RS18035
gene id: 323850:SHEW_RS18035
uniprot id: A3QIP6
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetyltransferase family. ArgA subfamily.
messages: Cytoplasm
messages: In bacteria which possess the bifunctional enzyme ornithine acetyltransferase/N-acetylglutamate synthase (ArgJ), ArgA fulfills an anaplerotic role.

323850:SHEW RS09425
gene id: 323850:SHEW_RS09425
uniprot id: A3QDZ1
names: Similarity
messages: Belongs to the PrpF family.

323850:SHEW RS03805
gene id: 323850:SHEW_RS03805
uniprot id: A3QAW3
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

323850:SHEW RS04870
gene id: 323850:SHEW_RS04870
uniprot id: A3QBH0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M32 family.
messages: Binds 1 zinc ion per subunit.
messages: Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues.

323850:SHEW RS09395
gene id: 323850:SHEW_RS09395
uniprot id: A3QDY5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thioester dehydratase family. FabA subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length.

323850:SHEW RS01175
gene id: 323850:SHEW_RS01175
uniprot id: A3Q9E9
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIS family. GmhA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
messages: Cytoplasm
messages: Homotetramer.
messages: The reaction produces a racemic mixture of D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate.

323850:SHEW RS03810
gene id: 323850:SHEW_RS03810
uniprot id: A3QAW4
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

323850:SHEW RS14555
gene id: 323850:SHEW_RS14555
uniprot id: A3QGT8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

323850:SHEW RS08305
gene id: 323850:SHEW_RS08305
uniprot id: A3QDC0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

323850:SHEW RS16585
gene id: 323850:SHEW_RS16585
uniprot id: A3QHX3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NapD family.
messages: Chaperone for NapA, the catalytic subunit of the periplasmic nitrate reductase. It binds directly and specifically to the twin-arginine signal peptide of NapA, preventing premature interaction with the Tat translocase and premature export.
messages: Cytoplasm
messages: Interacts with the cytoplasmic NapA precursor.

323850:SHEW RS04345
gene id: 323850:SHEW_RS04345
uniprot id: A3QB67
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

323850:SHEW RS17100
gene id: 323850:SHEW_RS17100
uniprot id: A3QI73
names: Subcellular Location Annotation
messages: Membrane

323850:SHEW RS02755
gene id: 323850:SHEW_RS02755
uniprot id: A3QAB2
names: Subcellular Location Annotation
messages: Membrane

323850:SHEW RS12955
gene id: 323850:SHEW_RS12955
uniprot id: A3QFX3
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

323850:SHEW RS08135
gene id: 323850:SHEW_RS08135
uniprot id: A3QD85
names: Similarity
messages: Belongs to the ClpA/ClpB family.

323850:SHEW RS13615
gene id: 323850:SHEW_RS13615
uniprot id: A3QG99
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di-trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide.
messages: Homodimer.

323850:SHEW RS16470
gene id: 323850:SHEW_RS16470
uniprot id: A3QHV0
names: Subcellular Location Annotation
messages: Periplasm

323850:SHEW RS11225
gene id: 323850:SHEW_RS11225
uniprot id: A3QEY2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

323850:SHEW RS06650
gene id: 323850:SHEW_RS06650
uniprot id: A3QCG6
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

323850:SHEW RS15125
gene id: 323850:SHEW_RS15125
uniprot id: A3QH42
names: Similarity
messages: Belongs to the PhoH family.

323850:SHEW RS05830
gene id: 323850:SHEW_RS05830
uniprot id: A3QC04
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

323850:SHEW RS09940
gene id: 323850:SHEW_RS09940
uniprot id: A3QE89
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SeqA family.
messages: Cytoplasm
messages: Homodimer. Polymerizes to form helical filaments.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re-initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated.

323850:SHEW RS19975
gene id: 323850:SHEW_RS19975
uniprot id: A3QJS1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

323850:SHEW RS15535
gene id: 323850:SHEW_RS15535
uniprot id: A3QHB9
names: Subcellular Location Annotation
messages: Membrane

323850:SHEW RS10435
gene id: 323850:SHEW_RS10435
uniprot id: A3QEI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsrE/TusD family.
messages: Cytoplasm

323850:SHEW RS12055
gene id: 323850:SHEW_RS12055
uniprot id: A3QFE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

323850:SHEW RS09400
gene id: 323850:SHEW_RS09400
uniprot id: A3QDY6
names: Similarity
messages: Belongs to the peptidase S16 family.

323850:SHEW RS06435
gene id: 323850:SHEW_RS06435
uniprot id: A3QCC1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

323850:SHEW RS03065
gene id: 323850:SHEW_RS03065
uniprot id: A3QAH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

323850:SHEW RS03175
gene id: 323850:SHEW_RS03175
uniprot id: A3QAJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane

323850:SHEW RS06410
gene id: 323850:SHEW_RS06410
uniprot id: A3QCB6
names: Similarity
messages: Belongs to the OsmC/Ohr family.

323850:SHEW RS19230
gene id: 323850:SHEW_RS19230
uniprot id: A3QJD1
names: Function
names: Similarity
messages: Belongs to the peptidase C56 family.
messages: Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate.

323850:SHEW RS01715
gene id: 323850:SHEW_RS01715
uniprot id: A3Q9Q4
names: Function
names: Similarity
messages: Belongs to the Dus family. DusB subfamily.
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

323850:SHEW RS14190
gene id: 323850:SHEW_RS14190
uniprot id: A3QGL5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PstS family.
messages: Involved in the system for phosphate transport across the cytoplasmic membrane.
messages: Periplasm
messages: Secreted

323850:SHEW RS18025
gene id: 323850:SHEW_RS18025
uniprot id: A3QIP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EamA transporter family.
messages: Membrane

323850:SHEW RS05200
gene id: 323850:SHEW_RS05200
uniprot id: A3QBN0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A highly abundant outer membrane lipoprotein that controls the distance between the inner and outer membranes. The only protein known to be covalently linked to the peptidoglycan network (PGN). Also non-covalently binds the PGN. The link between the cell outer membrane and PGN contributes to maintenance of the structural and functional integrity of the cell envelope, and maintains the correct distance between the PGN and the outer membrane.
messages: Belongs to the Lpp family.
messages: Cell outer membrane
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: cell wall

323850:SHEW RS08035
gene id: 323850:SHEW_RS08035
uniprot id: A3QD65
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

323850:SHEW RS01115
gene id: 323850:SHEW_RS01115
uniprot id: A3Q9D7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Monomer.

323850:SHEW RS17515
gene id: 323850:SHEW_RS17515
uniprot id: A3QIF4
names: Similarity
messages: Belongs to the band 7/mec-2 family.

323850:SHEW RS12710
gene id: 323850:SHEW_RS12710
uniprot id: A3QFS5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

323850:SHEW RS05570
gene id: 323850:SHEW_RS05570
uniprot id: A3QBV4
names: Similarity
messages: Belongs to the threonine synthase family.

323850:SHEW RS07525
gene id: 323850:SHEW_RS07525
uniprot id: A3QCX3
names: Similarity
messages: Belongs to the DEAD box helicase family.

323850:SHEW RS08610
gene id: 323850:SHEW_RS08610
uniprot id: A3QDI1
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 2 residues (Tyr-54 and Arg-57) present in a large hydrophobic pocket are probably involved in substrate specificity. They are important for desuccinylation activity, but dispensable for deacetylation activity.
messages: Belongs to the sirtuin family. Class III subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form.

323850:SHEW RS05425
gene id: 323850:SHEW_RS05425
uniprot id: A3QBS5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell inner membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

323850:SHEW RS19105
gene id: 323850:SHEW_RS19105
uniprot id: A3QJA6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

323850:SHEW RS09580
gene id: 323850:SHEW_RS09580
uniprot id: A3QE19
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

323850:SHEW RS03105
gene id: 323850:SHEW_RS03105
uniprot id: A3QAH7
names: Similarity
messages: Belongs to the Gfa family.

323850:SHEW RS10860
gene id: 323850:SHEW_RS10860
uniprot id: A3QER0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

323850:SHEW RS19180
gene id: 323850:SHEW_RS19180
uniprot id: A3QJC1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

323850:SHEW RS09960
gene id: 323850:SHEW_RS09960
uniprot id: A3QE93
names: Function
names: Similarity
messages: Belongs to the BCKDHA family.
messages: The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).

323850:SHEW RS05350
gene id: 323850:SHEW_RS05350
uniprot id: A3QBR0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MutH family.
messages: Cytoplasm
messages: Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair.

323850:SHEW RS14265
gene id: 323850:SHEW_RS14265
uniprot id: A3QGN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0382 family.
messages: Membrane

323850:SHEW RS03780
gene id: 323850:SHEW_RS03780
uniprot id: A3QAV8
names: Similarity
messages: Belongs to the SufE family.

323850:SHEW RS01495
gene id: 323850:SHEW_RS01495
uniprot id: A3Q9L3
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

323850:SHEW RS11210
gene id: 323850:SHEW_RS11210
uniprot id: A3QEX9
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

323850:SHEW RS05945
gene id: 323850:SHEW_RS05945
uniprot id: A3QC27
names: Similarity
names: Subunit
messages: Belongs to the threonine aldolase family.
messages: Homotetramer.

323850:SHEW RS07090
gene id: 323850:SHEW_RS07090
uniprot id: A3QCQ2
names: Function
names: Similarity
messages: Belongs to the GTP-binding SRP family.
messages: Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum.

323850:SHEW RS06615
gene id: 323850:SHEW_RS06615
uniprot id: A3QCF9
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.

323850:SHEW RS09005
gene id: 323850:SHEW_RS09005
uniprot id: A3QDQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

323850:SHEW RS10755
gene id: 323850:SHEW_RS10755
uniprot id: A3QEN9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

323850:SHEW RS10605
gene id: 323850:SHEW_RS10605
uniprot id: A3QEL6
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

323850:SHEW RS12900
gene id: 323850:SHEW_RS12900
uniprot id: A3QFW2
names: Subcellular Location Annotation
messages: Membrane

323850:SHEW RS10460
gene id: 323850:SHEW_RS10460
uniprot id: A3QEI8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.

323850:SHEW RS12925
gene id: 323850:SHEW_RS12925
uniprot id: A3QFW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

323850:SHEW RS14930
gene id: 323850:SHEW_RS14930
uniprot id: A3QH11
names: Similarity
messages: Belongs to the UPF0234 family.

323850:SHEW RS08175
gene id: 323850:SHEW_RS08175
uniprot id: A3QD93
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.
messages: In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: In the N-terminal section; belongs to the MIP18 family.

323850:SHEW RS18240
gene id: 323850:SHEW_RS18240
uniprot id: A3QIT8
names: Subcellular Location Annotation
messages: Membrane

323850:SHEW RS12960
gene id: 323850:SHEW_RS12960
uniprot id: A3QFX4
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

323850:SHEW RS00165
gene id: 323850:SHEW_RS00165
uniprot id: A3Q8V6
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

323850:SHEW RS04810
gene id: 323850:SHEW_RS04810
uniprot id: A3QBF8
names: Similarity
messages: Belongs to the peptidase S8 family.

323850:SHEW RS01515
gene id: 323850:SHEW_RS01515
uniprot id: A3Q9L7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
messages: Homotetramer.

323850:SHEW RS08110
gene id: 323850:SHEW_RS08110
uniprot id: A3QD80
names: Similarity
names: Subunit
messages: Belongs to the Nudix hydrolase family. NudJ subfamily.
messages: Monomer.

323850:SHEW RS06770
gene id: 323850:SHEW_RS06770
uniprot id: A3QCI9
names: Similarity
messages: Belongs to the polysaccharide synthase family.

323850:SHEW RS04175
gene id: 323850:SHEW_RS04175
uniprot id: A3QB33
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
messages: In the C-terminal section; belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

323850:SHEW RS00100
gene id: 323850:SHEW_RS00100
uniprot id: A3Q8U3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. Thiolase family.
messages: Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.
messages: Cytoplasm
messages: Heterotetramer of two alpha chains (FadB) and two beta chains (FadA).

323850:SHEW RS08250
gene id: 323850:SHEW_RS08250
uniprot id: A3QDA8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
messages: Cytoplasm
messages: Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity.

323850:SHEW RS10315
gene id: 323850:SHEW_RS10315
uniprot id: A3QEG3
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TtcA family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is chelated by three Cys residues, the fourth Fe has a free coordination site that may bind a sulfur atom transferred from the persulfide of IscS.
messages: Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
messages: Cytoplasm
messages: Homodimer.
messages: The thiolation reaction likely consists of two steps: a first activation step by ATP to form an adenylated intermediate of the target base of tRNA, and a second nucleophilic substitution step of the sulfur (S) atom supplied by the hydrosulfide attached to the Fe-S cluster.

323850:SHEW RS04435
gene id: 323850:SHEW_RS04435
uniprot id: A3QB86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

323850:SHEW RS10130
gene id: 323850:SHEW_RS10130
uniprot id: A3QEC5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LapB family.
messages: Cell inner membrane
messages: Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane.

323850:SHEW RS09770
gene id: 323850:SHEW_RS09770
uniprot id: A3QE56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

323850:SHEW RS12295
gene id: 323850:SHEW_RS12295
uniprot id: A3QFJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbA subfamily.
messages: Periplasm

323850:SHEW RS16210
gene id: 323850:SHEW_RS16210
uniprot id: A3QHQ2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

323850:SHEW RS00015
gene id: 323850:SHEW_RS00015
uniprot id: A3Q8S6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

323850:SHEW RS03110
gene id: 323850:SHEW_RS03110
uniprot id: A3QAH8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. RhlE subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in ribosome assembly. Has RNA-dependent ATPase activity and unwinds double-stranded RNA.

323850:SHEW RS00875
gene id: 323850:SHEW_RS00875
uniprot id: A3Q991
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

323850:SHEW RS09200
gene id: 323850:SHEW_RS09200
uniprot id: A3QDU9
names: Function
names: Similarity
messages: Belongs to the TrhO family.
messages: Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.

323850:SHEW RS19330
gene id: 323850:SHEW_RS19330
uniprot id: A3QJE7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the aerobic coproporphyrinogen-III oxidase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.

323850:SHEW RS04095
gene id: 323850:SHEW_RS04095
uniprot id: A3QB17
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.
messages: Serves to protect the cell against DNA damage by alkyl hydroperoxides. It can use either NADH or NADPH as electron donor for direct reduction of redox dyes or of alkyl hydroperoxides when combined with the AhpC protein.

323850:SHEW RS18750
gene id: 323850:SHEW_RS18750
uniprot id: A3QJ36
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: ATPase component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm. Acts as a molecular motor to provide the energy that is required for assembly of the pseudopilus and the extrusion of substrates generated in the cytoplasm.
messages: Belongs to the GSP E family.
messages: Cell inner membrane

323850:SHEW RS12095
gene id: 323850:SHEW_RS12095
uniprot id: A3QFF6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

323850:SHEW RS06610
gene id: 323850:SHEW_RS06610
uniprot id: A3QCF8
names: Subcellular Location Annotation
messages: Membrane

323850:SHEW RS13205
gene id: 323850:SHEW_RS13205
uniprot id: A3QG19
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MetA family.
messages: Cytoplasm
messages: Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine.

323850:SHEW RS11460
gene id: 323850:SHEW_RS11460
uniprot id: A3QF29
names: Similarity
messages: Belongs to the SAICAR synthetase family.

323850:SHEW RS13845
gene id: 323850:SHEW_RS13845
uniprot id: A3QGE4
names: Subcellular Location Annotation
messages: Membrane

323850:SHEW RS02890
gene id: 323850:SHEW_RS02890
uniprot id: A3QAD5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

323850:SHEW RS04360
gene id: 323850:SHEW_RS04360
uniprot id: A3QB70
names: Similarity
messages: Belongs to the P(II) protein family.

323850:SHEW RS02940
gene id: 323850:SHEW_RS02940
uniprot id: A3QAE5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b family.
messages: Binds 2 heme groups non-covalently.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

323850:SHEW RS11445
gene id: 323850:SHEW_RS11445
uniprot id: A3QF26
names: Similarity
messages: Belongs to the peptidase S8 family.

323850:SHEW RS00885
gene id: 323850:SHEW_RS00885
uniprot id: A3Q993
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

323850:SHEW RS00870
gene id: 323850:SHEW_RS00870
uniprot id: A3Q990
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

323850:SHEW RS07045
gene id: 323850:SHEW_RS07045
uniprot id: A3QCP3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell inner membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

323850:SHEW RS02280
gene id: 323850:SHEW_RS02280
uniprot id: A3QA18
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.
messages: Membrane

323850:SHEW RS01060
gene id: 323850:SHEW_RS01060
uniprot id: A3Q9C6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

323850:SHEW RS08095
gene id: 323850:SHEW_RS08095
uniprot id: A3QD77
names: Function
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
messages: Catalyzes two reactions in de novo purine nucleotide biosynthesis. Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate.

323850:SHEW RS06115
gene id: 323850:SHEW_RS06115
uniprot id: A3QC61
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

323850:SHEW RS18980
gene id: 323850:SHEW_RS18980
uniprot id: A3QJ82
names: Cofactor
names: Similarity
messages: Belongs to the RimK family.
messages: Binds 2 magnesium or manganese ions per subunit.

323850:SHEW RS18295
gene id: 323850:SHEW_RS18295
uniprot id: A3QIU8
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPAT/DAPAT family.
messages: Cell inner membrane
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

323850:SHEW RS15435
gene id: 323850:SHEW_RS15435
uniprot id: A3QH99
names: Similarity
messages: Belongs to the metallo-beta-lactamase superfamily. Type III sulfatase family.

323850:SHEW RS00680
gene id: 323850:SHEW_RS00680
uniprot id: A3Q960
names: Subcellular Location Annotation
messages: Membrane

323850:SHEW RS05185
gene id: 323850:SHEW_RS05185
uniprot id: A3QBM7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell inner membrane

323850:SHEW RS14195
gene id: 323850:SHEW_RS14195
uniprot id: A3QGL6
names: Function
messages: Member of the two-component regulatory system PhoR/PhoB involved in the phosphate regulon genes expression. PhoR may function as a membrane-associated protein kinase that phosphorylates PhoB in response to environmental signals.

323850:SHEW RS06740
gene id: 323850:SHEW_RS06740
uniprot id: A3QCI3
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

323850:SHEW RS07340
gene id: 323850:SHEW_RS07340
uniprot id: A3QCV1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NapF family.
messages: Could be involved in the maturation of NapA, the catalytic subunit of the periplasmic nitrate reductase, before its export into the periplasm.
messages: Cytoplasm
messages: Interacts with the cytoplasmic NapA precursor.

323850:SHEW RS09495
gene id: 323850:SHEW_RS09495
uniprot id: A3QE02
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

323850:SHEW RS08220
gene id: 323850:SHEW_RS08220
uniprot id: A3QDA2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Cytoplasm
messages: Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA.

323850:SHEW RS11145
gene id: 323850:SHEW_RS11145
uniprot id: A3QEW6
names: Subcellular Location Annotation
messages: Cell inner membrane

323850:SHEW RS17285
gene id: 323850:SHEW_RS17285
uniprot id: A3QIA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

323850:SHEW RS16870
gene id: 323850:SHEW_RS16870
uniprot id: A3QI27
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Member of a two-component regulatory system.

323850:SHEW RS01570
gene id: 323850:SHEW_RS01570
uniprot id: A3Q9M8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiK family.
messages: Cytoplasm
messages: Required for efficient ubiquinone (coenzyme Q) biosynthesis. UbiK is probably an accessory factor of Ubi enzymes and facilitates ubiquinone biosynthesis by acting as an assembly factor, a targeting factor, or both.

323850:SHEW RS18065
gene id: 323850:SHEW_RS18065
uniprot id: A3QIQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nucleoid occlusion factor SlmA family.
messages: Homodimer. Interacts with FtsZ.
messages: Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions.
messages: nucleoid

323850:SHEW RS16560
gene id: 323850:SHEW_RS16560
uniprot id: A3QHW8
names: Subcellular Location Annotation
messages: Cell inner membrane

323850:SHEW RS03305
gene id: 323850:SHEW_RS03305
uniprot id: A3QAL7
names: Subcellular Location Annotation
messages: Membrane

323850:SHEW RS15775
gene id: 323850:SHEW_RS15775
uniprot id: A3QHG7
names: Subcellular Location Annotation
messages: Membrane

323850:SHEW RS12510
gene id: 323850:SHEW_RS12510
uniprot id: A3QFN4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

323850:SHEW RS14565
gene id: 323850:SHEW_RS14565
uniprot id: A3QGU0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

323850:SHEW RS13375
gene id: 323850:SHEW_RS13375
uniprot id: A3QG52
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

323850:SHEW RS15040
gene id: 323850:SHEW_RS15040
uniprot id: A3QH33
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

323850:SHEW RS06695
gene id: 323850:SHEW_RS06695
uniprot id: A3QCH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

323850:SHEW RS12750
gene id: 323850:SHEW_RS12750
uniprot id: A3QFT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

323850:SHEW RS17310
gene id: 323850:SHEW_RS17310
uniprot id: A3QIB3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the diacylglycerol/lipid kinase family. YegS lipid kinase subfamily.
messages: Binds 1 Mg(2+) ion per subunit. Ca(2+) may be able to substitute.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably phosphorylates lipids; the in vivo substrate is unknown.

323850:SHEW RS13245
gene id: 323850:SHEW_RS13245
uniprot id: A3QG26
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MenA family. Type 1 subfamily.
messages: Cell inner membrane
messages: Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

323850:SHEW RS00055
gene id: 323850:SHEW_RS00055
uniprot id: A3Q8T4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

323850:SHEW RS12945
gene id: 323850:SHEW_RS12945
uniprot id: A3QFX1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TER reductase family.
messages: Involved in the final reduction of the elongation cycle of fatty acid synthesis (FAS II). Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP).
messages: Monomer.

323850:SHEW RS01000
gene id: 323850:SHEW_RS01000
uniprot id: A3Q9B8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbE subfamily.
messages: Cell inner membrane

323850:SHEW RS11135
gene id: 323850:SHEW_RS11135
uniprot id: A3QEW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

323850:SHEW RS13580
gene id: 323850:SHEW_RS13580
uniprot id: A3QG92
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

323850:SHEW RS11280
gene id: 323850:SHEW_RS11280
uniprot id: A3QEZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaB Na(+)/H(+) (TC 2.A.34) antiporter family.
messages: Cell inner membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

323850:SHEW RS07280
gene id: 323850:SHEW_RS07280
uniprot id: A3QCT9
names: Cofactor
names: Similarity
messages: Belongs to the PHP family.
messages: Binds 3 Zn(2+) ions per subunit.

323850:SHEW RS11275
gene id: 323850:SHEW_RS11275
uniprot id: A3QEZ2
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Homodimer.
messages: Multifunctional regulator of fatty acid metabolism.

323850:SHEW RS12235
gene id: 323850:SHEW_RS12235
uniprot id: A3QFH9
names: Similarity
messages: Belongs to the proline racemase family.

323850:SHEW RS01665
gene id: 323850:SHEW_RS01665
uniprot id: A3Q9P3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-1 family.
messages: Cytoplasm

323850:SHEW RS19540
gene id: 323850:SHEW_RS19540
uniprot id: A3QJI9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family.
messages: Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).
messages: Binds 1 Mg(2+) ion per subunit.
messages: Monomer.

323850:SHEW RS17125
gene id: 323850:SHEW_RS17125
uniprot id: A3QI78
names: Function
names: Similarity
messages: Belongs to the ABC transporter superfamily. Outer membrane lipopolysaccharide export (TC 1.B.42) family.
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane. Probably responsible for energy coupling to the transport system.

323850:SHEW RS07185
gene id: 323850:SHEW_RS07185
uniprot id: A3QCS1
names: Subcellular Location Annotation
messages: Membrane

323850:SHEW RS04520
gene id: 323850:SHEW_RS04520
uniprot id: A3QBA3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

323850:SHEW RS00960
gene id: 323850:SHEW_RS00960
uniprot id: A3Q9B0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmE/CycJ family.
messages: Cell inner membrane
messages: Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.

323850:SHEW RS03870
gene id: 323850:SHEW_RS03870
uniprot id: A3QAX6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

323850:SHEW RS08145
gene id: 323850:SHEW_RS08145
uniprot id: A3QD87
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the R-transferase family. Bpt subfamily.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate.

323850:SHEW RS00675
gene id: 323850:SHEW_RS00675
uniprot id: A3Q959
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the selenophosphate synthase 1 family. Class I subfamily.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Homodimer.
messages: Synthesizes selenophosphate from selenide and ATP.

323850:SHEW RS05855
gene id: 323850:SHEW_RS05855
uniprot id: A3QC09
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

323850:SHEW RS04560
gene id: 323850:SHEW_RS04560
uniprot id: A3QBB1
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

323850:SHEW RS00530
gene id: 323850:SHEW_RS00530
uniprot id: A3Q930
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NfuA family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is presumably bound at the interface of two monomers.
messages: Homodimer.
messages: Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins.

323850:SHEW RS10075
gene id: 323850:SHEW_RS10075
uniprot id: A3QEB4
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

323850:SHEW RS13435
gene id: 323850:SHEW_RS13435
uniprot id: A3QG64
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

323850:SHEW RS13920
gene id: 323850:SHEW_RS13920
uniprot id: A3QGG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HupC/HyaC/HydC family.
messages: Membrane

323850:SHEW RS14395
gene id: 323850:SHEW_RS14395
uniprot id: A3QGQ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase U32 family. UbiV subfamily.
messages: Forms an heterodimer with UbiU.
messages: Required for O(2)-independent ubiquinone (coenzyme Q) biosynthesis. Together with UbiU, is essential for the C6-hydroxylation reaction in the oxygen-independent ubiquinone biosynthesis pathway.

323850:SHEW RS08800
gene id: 323850:SHEW_RS08800
uniprot id: A3QDL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

323850:SHEW RS01710
gene id: 323850:SHEW_RS01710
uniprot id: A3Q9Q3
names: Function
names: Similarity
names: Subunit
messages: Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters.
messages: Belongs to the transcriptional regulatory Fis family.
messages: Homodimer.

323850:SHEW RS14870
gene id: 323850:SHEW_RS14870
uniprot id: A3QGZ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NqrA family.
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

323850:SHEW RS04720
gene id: 323850:SHEW_RS04720
uniprot id: A3QBE2
names: Subcellular Location Annotation
messages: Membrane

323850:SHEW RS10655
gene id: 323850:SHEW_RS10655
uniprot id: A3QEM6
names: Similarity
messages: Belongs to the UPF0381 family.

323850:SHEW RS06125
gene id: 323850:SHEW_RS06125
uniprot id: A3QC63
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

323850:SHEW RS18720
gene id: 323850:SHEW_RS18720
uniprot id: A3QJ30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP K family.
messages: Cell inner membrane
messages: Membrane

323850:SHEW RS17740
gene id: 323850:SHEW_RS17740
uniprot id: A3QIJ9
names: Function
names: Subunit
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
messages: Homodimer. Part of the PDH complex, consisting of multiple copies of pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

323850:SHEW RS04455
gene id: 323850:SHEW_RS04455
uniprot id: A3QB90
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

323850:SHEW RS13815
gene id: 323850:SHEW_RS13815
uniprot id: A3QGD8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

323850:SHEW RS19720
gene id: 323850:SHEW_RS19720
uniprot id: A3QJM4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

323850:SHEW RS13505
gene id: 323850:SHEW_RS13505
uniprot id: A3QG77
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

323850:SHEW RS15100
gene id: 323850:SHEW_RS15100
uniprot id: A3QH37
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

323850:SHEW RS14440
gene id: 323850:SHEW_RS14440
uniprot id: A3QGR5
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TorC/TorY family.
messages: Binds 5 heme groups per subunit.
messages: Cell inner membrane
messages: Membrane

323850:SHEW RS11545
gene id: 323850:SHEW_RS11545
uniprot id: A3QF46
names: Function
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.
messages: Catalyzes the phosphorylation of guanosine and inosine to GMP and IMP, respectively.

323850:SHEW RS03730
gene id: 323850:SHEW_RS03730
uniprot id: A3QAU9
names: Subcellular Location Annotation
messages: Membrane

323850:SHEW RS14750
gene id: 323850:SHEW_RS14750
uniprot id: A3QGX5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

323850:SHEW RS12370
gene id: 323850:SHEW_RS12370
uniprot id: A3QFK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FNT transporter (TC 2.A.44) family.
messages: Membrane

323850:SHEW RS17050
gene id: 323850:SHEW_RS17050
uniprot id: A3QI63
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AFG1 ATPase family. ZapE subfamily.
messages: Cytoplasm
messages: Interacts with FtsZ.
messages: Reduces the stability of FtsZ polymers in the presence of ATP.

323850:SHEW RS00615
gene id: 323850:SHEW_RS00615
uniprot id: A3Q947
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COX11/CtaG family.
messages: Cell inner membrane
messages: Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I.

323850:SHEW RS08150
gene id: 323850:SHEW_RS08150
uniprot id: A3QD88
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

323850:SHEW RS13525
gene id: 323850:SHEW_RS13525
uniprot id: A3QG81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

323850:SHEW RS00625
gene id: 323850:SHEW_RS00625
uniprot id: A3Q949
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Binds a copper A center.
messages: Cell membrane
messages: Membrane
messages: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).

323850:SHEW RS20020
gene id: 323850:SHEW_RS20020
uniprot id: A3QJT0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.

323850:SHEW RS04885
gene id: 323850:SHEW_RS04885
uniprot id: A3QBH3
names: Similarity
messages: Belongs to the DEAD box helicase family.

323850:SHEW RS18085
gene id: 323850:SHEW_RS18085
uniprot id: A3QIQ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

323850:SHEW RS08545
gene id: 323850:SHEW_RS08545
uniprot id: A3QDG8
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

323850:SHEW RS13305
gene id: 323850:SHEW_RS13305
uniprot id: A3QG38
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

323850:SHEW RS18920
gene id: 323850:SHEW_RS18920
uniprot id: A3QJ70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

323850:SHEW RS13780
gene id: 323850:SHEW_RS13780
uniprot id: A3QGD1
names: Function
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.

323850:SHEW RS17510
gene id: 323850:SHEW_RS17510
uniprot id: A3QIF3
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

323850:SHEW RS11865
gene id: 323850:SHEW_RS11865
uniprot id: A3QFB0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

323850:SHEW RS08465
gene id: 323850:SHEW_RS08465
uniprot id: A3QDF2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family.
messages: Cell inner membrane
messages: Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.
messages: The complex is composed of two ATP-binding proteins (LolD) and two transmembrane proteins (LolC and LolE).

323850:SHEW RS09410
gene id: 323850:SHEW_RS09410
uniprot id: A3QDY8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.
messages: Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate.
messages: Homotetramer; dimer of dimers.
messages: Involved in the catabolism of short chain fatty acids (SCFA) via the 2-methylcitrate cycle (propionate degradation route). Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate via an alpha-carboxy-carbanion intermediate.

323850:SHEW RS13605
gene id: 323850:SHEW_RS13605
uniprot id: A3QG97
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).

323850:SHEW RS11195
gene id: 323850:SHEW_RS11195
uniprot id: A3QEX6
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaved by autocatalysis into a large and a small subunit.
messages: This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide.

323850:SHEW RS04415
gene id: 323850:SHEW_RS04415
uniprot id: A3QB82
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

323850:SHEW RS16670
gene id: 323850:SHEW_RS16670
uniprot id: A3QHZ0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SprT family.
messages: Binds 1 zinc ion.
messages: Cytoplasm

323850:SHEW RS13860
gene id: 323850:SHEW_RS13860
uniprot id: A3QGE7
names: Function
names: Similarity
messages: Belongs to the ETF-QO/FixC family.
messages: Part of an electron transfer system.

323850:SHEW RS09435
gene id: 323850:SHEW_RS09435
uniprot id: A3QDZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

323850:SHEW RS12605
gene id: 323850:SHEW_RS12605
uniprot id: A3QFQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

323850:SHEW RS16320
gene id: 323850:SHEW_RS16320
uniprot id: A3QHS0
names: Similarity
messages: Belongs to the peptidase S8 family.

323850:SHEW RS16350
gene id: 323850:SHEW_RS16350
uniprot id: A3QHS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

323850:SHEW RS19480
gene id: 323850:SHEW_RS19480
uniprot id: A3QJH7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. HutI family.
messages: Binds 1 zinc or iron ion per subunit.
messages: Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate. It is the third step in the universal histidine degradation pathway.
messages: Cytoplasm

323850:SHEW RS11950
gene id: 323850:SHEW_RS11950
uniprot id: A3QFC7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. PdxB subfamily.
messages: Catalyzes the oxidation of erythronate-4-phosphate to 3-hydroxy-2-oxo-4-phosphonooxybutanoate.
messages: Cytoplasm
messages: Homodimer.

323850:SHEW RS19515
gene id: 323850:SHEW_RS19515
uniprot id: A3QJI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

323850:SHEW RS01510
gene id: 323850:SHEW_RS01510
uniprot id: A3Q9L6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.

323850:SHEW RS14340
gene id: 323850:SHEW_RS14340
uniprot id: A3QGP5
names: Similarity
messages: Belongs to the DEAD box helicase family.

323850:SHEW RS06955
gene id: 323850:SHEW_RS06955
uniprot id: A3QCM5
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

323850:SHEW RS11555
gene id: 323850:SHEW_RS11555
uniprot id: A3QF48
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Monomer.

323850:SHEW RS01805
gene id: 323850:SHEW_RS01805
uniprot id: A3Q9S2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multiheme cytochrome c family.
messages: Binds 8 heme c groups covalently per monomer.
messages: Exposure to oxygen reduces copper binding and leads to the formation of a disulfide bond between the two Cys residues that bind the copper ion.
messages: Periplasm
messages: Respiratory sulfite reductase that catalyzes the reduction of sulfite to sulfide in a single step, consuming six electrons in the process.

323850:SHEW RS14650
gene id: 323850:SHEW_RS14650
uniprot id: A3QGV5
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

323850:SHEW RS01905
gene id: 323850:SHEW_RS01905
uniprot id: A3Q9U1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Heterooctamer of two A chains, two B chains, two C chains and two D chains.
messages: Membrane

323850:SHEW RS10100
gene id: 323850:SHEW_RS10100
uniprot id: A3QEB9
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

323850:SHEW RS05250
gene id: 323850:SHEW_RS05250
uniprot id: A3QBP0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HesB/IscA family.
messages: Binds 1 iron-sulfur cluster per subunit.
messages: Homodimer.
messages: Required for insertion of 4Fe-4S clusters for at least IspG.

323850:SHEW RS07970
gene id: 323850:SHEW_RS07970
uniprot id: A3QD53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

323850:SHEW RS17275
gene id: 323850:SHEW_RS17275
uniprot id: A3QIA7
names: Similarity
messages: Belongs to the Gfa family.

323850:SHEW RS18400
gene id: 323850:SHEW_RS18400
uniprot id: A3QIW9
names: Subcellular Location Annotation
messages: Membrane

323850:SHEW RS16450
gene id: 323850:SHEW_RS16450
uniprot id: A3QHU6
names: Subcellular Location Annotation
messages: Membrane

323850:SHEW RS01725
gene id: 323850:SHEW_RS01725
uniprot id: A3Q9Q6
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: The fumarate reductase enzyme complex is required for fumarate respiration. This subunit anchors the complex in the membrane and binds a diheme cytochrome b.

323850:SHEW RS05490
gene id: 323850:SHEW_RS05490
uniprot id: A3QBT8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

323850:SHEW RS12385
gene id: 323850:SHEW_RS12385
uniprot id: A3QFK9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activation of pyruvate formate-lyase 1 under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm

323850:SHEW RS19385
gene id: 323850:SHEW_RS19385
uniprot id: A3QJF8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrkH potassium transport family.
messages: Cell inner membrane
messages: Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA.
messages: Membrane

323850:SHEW RS03020
gene id: 323850:SHEW_RS03020
uniprot id: A3QAG1
names: Similarity
messages: Belongs to the phosphoribulokinase family.

323850:SHEW RS09700
gene id: 323850:SHEW_RS09700
uniprot id: A3QE43
names: Subcellular Location Annotation
messages: Secreted

323850:SHEW RS05645
gene id: 323850:SHEW_RS05645
uniprot id: A3QBW9
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

323850:SHEW RS06135
gene id: 323850:SHEW_RS06135
uniprot id: A3QC65
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG).

323850:SHEW RS01440
gene id: 323850:SHEW_RS01440
uniprot id: A3Q9K2
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

323850:SHEW RS16980
gene id: 323850:SHEW_RS16980
uniprot id: A3QI49
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

323850:SHEW RS15290
gene id: 323850:SHEW_RS15290
uniprot id: A3QH70
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

323850:SHEW RS15425
gene id: 323850:SHEW_RS15425
uniprot id: A3QH97
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueG family.
messages: Binds 2 [4Fe-4S] clusters per monomer.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

323850:SHEW RS01065
gene id: 323850:SHEW_RS01065
uniprot id: A3Q9C7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

323850:SHEW RS09010
gene id: 323850:SHEW_RS09010
uniprot id: A3QDQ9
names: Cofactor
names: Similarity
messages: Belongs to the nitroreductase family.
messages: Binds 1 FMN per subunit.

323850:SHEW RS09545
gene id: 323850:SHEW_RS09545
uniprot id: A3QE12
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

323850:SHEW RS02355
gene id: 323850:SHEW_RS02355
uniprot id: A3QA32
names: Similarity
messages: Belongs to the PhoH family.

323850:SHEW RS17735
gene id: 323850:SHEW_RS17735
uniprot id: A3QIJ8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 3 lipoyl cofactors covalently.
messages: Forms a 24-polypeptide structural core with octahedral symmetry.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

323850:SHEW RS14535
gene id: 323850:SHEW_RS14535
uniprot id: A3QGT4
names: Similarity
messages: Belongs to the nucleoside-specific channel-forming outer membrane porin (Tsx) (TC 1.B.10) family.

323850:SHEW RS05355
gene id: 323850:SHEW_RS05355
uniprot id: A3QBR1
names: Function
names: Similarity
messages: Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
messages: Belongs to the Nudix hydrolase family. RppH subfamily.

323850:SHEW RS08565
gene id: 323850:SHEW_RS08565
uniprot id: A3QDH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Cell inner membrane
messages: Membrane

323850:SHEW RS04305
gene id: 323850:SHEW_RS04305
uniprot id: A3QB59
names: Similarity
messages: Belongs to the peptidase M1 family.

323850:SHEW RS12435
gene id: 323850:SHEW_RS12435
uniprot id: A3QFL9
names: Subcellular Location Annotation
messages: Membrane

323850:SHEW RS14480
gene id: 323850:SHEW_RS14480
uniprot id: A3QGS3
names: Similarity
messages: Belongs to the peptidase C59 family.

323850:SHEW RS10135
gene id: 323850:SHEW_RS10135
uniprot id: A3QEC6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

323850:SHEW RS08440
gene id: 323850:SHEW_RS08440
uniprot id: A3QDE7
names: Similarity
messages: Belongs to the acylphosphatase family.

323850:SHEW RS10980
gene id: 323850:SHEW_RS10980
uniprot id: A3QET2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Monomer.
messages: Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.

323850:SHEW RS16935
gene id: 323850:SHEW_RS16935
uniprot id: A3QI40
names: Similarity
messages: Belongs to the aldose epimerase family.

323850:SHEW RS18600
gene id: 323850:SHEW_RS18600
uniprot id: A3QJ06
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

323850:SHEW RS17660
gene id: 323850:SHEW_RS17660
uniprot id: A3QII3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

323850:SHEW RS00690
gene id: 323850:SHEW_RS00690
uniprot id: A3Q962
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. TrmA subfamily.
messages: Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA).

323850:SHEW RS13565
gene id: 323850:SHEW_RS13565
uniprot id: A3QG89
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

323850:SHEW RS19860
gene id: 323850:SHEW_RS19860
uniprot id: A3QJP9
names: Similarity
messages: Belongs to the metallo-beta-lactamase superfamily. Class-B beta-lactamase family.
messages: Belongs to the metallo-beta-lactamase superfamily. Type III sulfatase family.

323850:SHEW RS02525
gene id: 323850:SHEW_RS02525
uniprot id: A3QA66
names: Similarity
messages: Belongs to the hemerythrin family.

323850:SHEW RS14000
gene id: 323850:SHEW_RS14000
uniprot id: A3QGH6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell inner membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

323850:SHEW RS07670
gene id: 323850:SHEW_RS07670
uniprot id: A3QD00
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

323850:SHEW RS02820
gene id: 323850:SHEW_RS02820
uniprot id: A3QAC5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.
messages: Cell membrane
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

323850:SHEW RS17405
gene id: 323850:SHEW_RS17405
uniprot id: A3QID2
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

323850:SHEW RS14895
gene id: 323850:SHEW_RS14895
uniprot id: A3QH04
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RlmG family.
messages: Cytoplasm
messages: Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA.

323850:SHEW RS17365
gene id: 323850:SHEW_RS17365
uniprot id: A3QIC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

323850:SHEW RS06730
gene id: 323850:SHEW_RS06730
uniprot id: A3QCI1
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

323850:SHEW RS06295
gene id: 323850:SHEW_RS06295
uniprot id: A3QC93
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GcdB/MmdB/OadB family.
messages: Catalyzes the decarboxylation of oxaloacetate coupled to Na(+) translocation.
messages: Cell membrane
messages: Heterotrimer of an alpha, a beta and a gamma subunit.
messages: Membrane

323850:SHEW RS03585
gene id: 323850:SHEW_RS03585
uniprot id: A3QAS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaD Na(+)/H(+) (TC 2.A.62) antiporter family.
messages: Membrane

323850:SHEW RS11480
gene id: 323850:SHEW_RS11480
uniprot id: A3QF33
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

323850:SHEW RS18735
gene id: 323850:SHEW_RS18735
uniprot id: A3QJ33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP H family.
messages: Cell inner membrane
messages: Membrane

323850:SHEW RS01740
gene id: 323850:SHEW_RS01740
uniprot id: A3Q9Q9
names: Cofactor
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.

323850:SHEW RS08920
gene id: 323850:SHEW_RS08920
uniprot id: A3QDP1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

323850:SHEW RS01900
gene id: 323850:SHEW_RS01900
uniprot id: A3Q9U0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Cell membrane
messages: Membrane

323850:SHEW RS07965
gene id: 323850:SHEW_RS07965
uniprot id: A3QD52
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.

323850:SHEW RS01110
gene id: 323850:SHEW_RS01110
uniprot id: A3Q9D6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial secretin family. PilQ subfamily.
messages: Cell outer membrane
messages: Membrane

323850:SHEW RS14310
gene id: 323850:SHEW_RS14310
uniprot id: A3QGN9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

323850:SHEW RS16260
gene id: 323850:SHEW_RS16260
uniprot id: A3QHR1
names: Caution
names: Function
names: Similarity
messages: Belongs to the UbiX/PAD1 family.
messages: Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

323850:SHEW RS18840
gene id: 323850:SHEW_RS18840
uniprot id: A3QJ54
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family. GreB subfamily.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length.

323850:SHEW RS14285
gene id: 323850:SHEW_RS14285
uniprot id: A3QGN4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThiI family.
messages: Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
messages: Cytoplasm

323850:SHEW RS15270
gene id: 323850:SHEW_RS15270
uniprot id: A3QH67
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

323850:SHEW RS05480
gene id: 323850:SHEW_RS05480
uniprot id: A3QBT6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

323850:SHEW RS16985
gene id: 323850:SHEW_RS16985
uniprot id: A3QI50
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

323850:SHEW RS11085
gene id: 323850:SHEW_RS11085
uniprot id: A3QEV3
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

323850:SHEW RS07025
gene id: 323850:SHEW_RS07025
uniprot id: A3QCN9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliH family.
messages: Cytoplasm
messages: Needed for flagellar regrowth and assembly.

323850:SHEW RS11370
gene id: 323850:SHEW_RS11370
uniprot id: A3QF11
names: Similarity
messages: Belongs to the KAE1 / TsaD family. TsaB subfamily.

323850:SHEW RS15860
gene id: 323850:SHEW_RS15860
uniprot id: A3QHI3
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

323850:SHEW RS00825
gene id: 323850:SHEW_RS00825
uniprot id: A3Q981
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

323850:SHEW RS11055
gene id: 323850:SHEW_RS11055
uniprot id: A3QEU7
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild-type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity.
messages: Belongs to the RecC family.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding.

323850:SHEW RS01645
gene id: 323850:SHEW_RS01645
uniprot id: A3Q9N9
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Involved in a late step of protoheme IX synthesis.
messages: Membrane

323850:SHEW RS02315
gene id: 323850:SHEW_RS02315
uniprot id: A3QA25
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RraB family.
messages: Cytoplasm
messages: Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome.
messages: Interacts with the C-terminal region of Rne.

323850:SHEW RS11945
gene id: 323850:SHEW_RS11945
uniprot id: A3QFC6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

323850:SHEW RS10765
gene id: 323850:SHEW_RS10765
uniprot id: A3QEP1
names: Similarity
messages: Belongs to the glyoxalase I family.

323850:SHEW RS08215
gene id: 323850:SHEW_RS08215
uniprot id: A3QDA1
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.

323850:SHEW RS05340
gene id: 323850:SHEW_RS05340
uniprot id: A3QBQ8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

323850:SHEW RS14170
gene id: 323850:SHEW_RS14170
uniprot id: A3QGL0
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

323850:SHEW RS14210
gene id: 323850:SHEW_RS14210
uniprot id: A3QGL9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RdgC family.
messages: May be involved in recombination.
messages: nucleoid

323850:SHEW RS06020
gene id: 323850:SHEW_RS06020
uniprot id: A3QC42
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

323850:SHEW RS04330
gene id: 323850:SHEW_RS04330
uniprot id: A3QB64
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

323850:SHEW RS04915
gene id: 323850:SHEW_RS04915
uniprot id: A3QBH9
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

323850:SHEW RS06230
gene id: 323850:SHEW_RS06230
uniprot id: A3QC85
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoS subfamily.
messages: Cytoplasm
messages: Interacts with the RNA polymerase core enzyme.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the master transcriptional regulator of the stationary phase and the general stress response.

323850:SHEW RS13100
gene id: 323850:SHEW_RS13100
uniprot id: A3QFZ9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

323850:SHEW RS03995
gene id: 323850:SHEW_RS03995
uniprot id: A3QAZ7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.

323850:SHEW RS14080
gene id: 323850:SHEW_RS14080
uniprot id: A3QGJ2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pseudouridine-5'-phosphate glycosidase family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the reversible cleavage of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway.
messages: Homotrimer.

323850:SHEW RS06320
gene id: 323850:SHEW_RS06320
uniprot id: A3QC98
names: Similarity
messages: Belongs to the peptidase M16 family.

323850:SHEW RS14330
gene id: 323850:SHEW_RS14330
uniprot id: A3QGP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.
messages: Cell membrane

323850:SHEW RS03865
gene id: 323850:SHEW_RS03865
uniprot id: A3QAX5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

323850:SHEW RS04735
gene id: 323850:SHEW_RS04735
uniprot id: A3QBE5
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

323850:SHEW RS00450
gene id: 323850:SHEW_RS00450
uniprot id: A3Q913
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

323850:SHEW RS04865
gene id: 323850:SHEW_RS04865
uniprot id: A3QBG9
names: Similarity
messages: Belongs to the band 7/mec-2 family. Flotillin subfamily.

323850:SHEW RS04170
gene id: 323850:SHEW_RS04170
uniprot id: A3QB32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

323850:SHEW RS08390
gene id: 323850:SHEW_RS08390
uniprot id: A3QDD7
names: Similarity
messages: Belongs to the CvfB family.

323850:SHEW RS05890
gene id: 323850:SHEW_RS05890
uniprot id: A3QC16
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

323850:SHEW RS12910
gene id: 323850:SHEW_RS12910
uniprot id: A3QFW4
names: Similarity
messages: Belongs to the PspA/IM30 family.

323850:SHEW RS05985
gene id: 323850:SHEW_RS05985
uniprot id: A3QC35
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

323850:SHEW RS18800
gene id: 323850:SHEW_RS18800
uniprot id: A3QJ46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Cell inner membrane
messages: Membrane

323850:SHEW RS01675
gene id: 323850:SHEW_RS01675
uniprot id: A3Q9P6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

323850:SHEW RS12020
gene id: 323850:SHEW_RS12020
uniprot id: A3QFE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PsiE family.
messages: Cell inner membrane
messages: Membrane

323850:SHEW RS16220
gene id: 323850:SHEW_RS16220
uniprot id: A3QHQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lactate permease family.
messages: Cell inner membrane
messages: Membrane
messages: Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate.

323850:SHEW RS09125
gene id: 323850:SHEW_RS09125
uniprot id: A3QDT3
names: Similarity
names: Subunit
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family.
messages: Heterodimer of a large and a small subunit.

323850:SHEW RS07050
gene id: 323850:SHEW_RS07050
uniprot id: A3QCP4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Cell inner membrane
messages: FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

323850:SHEW RS17895
gene id: 323850:SHEW_RS17895
uniprot id: A3QIL8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell inner membrane
messages: Self-interacts. Interacts with FtsZ.

323850:SHEW RS10785
gene id: 323850:SHEW_RS10785
uniprot id: A3QEP5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RuvC family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.

323850:SHEW RS06360
gene id: 323850:SHEW_RS06360
uniprot id: A3QCA6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S41B family.
messages: Cytoplasm
messages: Degrades oligopeptides.

323850:SHEW RS02790
gene id: 323850:SHEW_RS02790
uniprot id: A3QAB9
names: Function
names: Similarity
messages: Acts on ADP-mannose and ADP-glucose as well as ADP-ribose. Prevents glycogen biosynthesis. The reaction catalyzed by this enzyme is a limiting step of the gluconeogenic process.
messages: Belongs to the Nudix hydrolase family. NudF subfamily.

323850:SHEW RS13085
gene id: 323850:SHEW_RS13085
uniprot id: A3QFZ6
names: Similarity
messages: Belongs to the CdaR family.

323850:SHEW RS10490
gene id: 323850:SHEW_RS10490
uniprot id: A3QEJ4
names: Similarity
messages: Belongs to the AlaDH/PNT family.

323850:SHEW RS10425
gene id: 323850:SHEW_RS10425
uniprot id: A3QEI1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

323850:SHEW RS01360
gene id: 323850:SHEW_RS01360
uniprot id: A3Q9I6
names: Function
names: Similarity
messages: Belongs to the SELO family.
messages: Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).

323850:SHEW RS17620
gene id: 323850:SHEW_RS17620
uniprot id: A3QIH5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

323850:SHEW RS17585
gene id: 323850:SHEW_RS17585
uniprot id: A3QIG8
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NosZ family.
messages: Binds 2 calcium ions per subunit.
messages: Binds 6 Cu cations per subunit. Each subunit contains 2 copper centers; Cu(A) (binuclear) and Cu(Z) (tetranuclear). Cu(Z) is thought to be the site of nitrous oxide reduction.
messages: Homodimer.
messages: In the C-terminal section; belongs to the cytochrome c oxidase subunit 2 family.
messages: Nitrous-oxide reductase is part of a bacterial respiratory system which is activated under anaerobic conditions in the presence of nitrate or nitrous oxide.
messages: Periplasm
messages: Predicted to be exported by the Tat system. The position of the signal peptide cleavage has not been experimentally proven.

323850:SHEW RS11065
gene id: 323850:SHEW_RS11065
uniprot id: A3QEU9
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD.
messages: Belongs to the RecD family.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding.

323850:SHEW RS03885
gene id: 323850:SHEW_RS03885
uniprot id: A3QAX9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.
messages: One is catalytic and the other provides a structural contribution.

323850:SHEW RS02025
gene id: 323850:SHEW_RS02025
uniprot id: A3Q9W6
names: Similarity
messages: Belongs to the GSP E family.

323850:SHEW RS04530
gene id: 323850:SHEW_RS04530
uniprot id: A3QBA5
names: Domain
names: Function
names: Subcellular Location Annotation
messages: Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation.
messages: Periplasm
messages: The PPIase activity resides only in the second parvulin domain. The N-terminal region and the C-terminal tail are necessary and sufficient for the chaperone activity of SurA. The PPIase activity is dispensable for SurA to function as a chaperone. The N-terminal region and the C-terminal tail are also required for porin recognition.

323850:SHEW RS16930
gene id: 323850:SHEW_RS16930
uniprot id: A3QI39
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. GalK subfamily.
messages: Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P).
messages: Cytoplasm

323850:SHEW RS07955
gene id: 323850:SHEW_RS07955
uniprot id: A3QD50
names: Subunit
messages: Monomer.

323850:SHEW RS17040
gene id: 323850:SHEW_RS17040
uniprot id: A3QI61
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

323850:SHEW RS13325
gene id: 323850:SHEW_RS13325
uniprot id: A3QG42
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

323850:SHEW RS00765
gene id: 323850:SHEW_RS00765
uniprot id: A3Q969
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

323850:SHEW RS03025
gene id: 323850:SHEW_RS03025
uniprot id: A3QAG2
names: Similarity
messages: Belongs to the UPF0270 family.

323850:SHEW RS08665
gene id: 323850:SHEW_RS08665
uniprot id: A3QDJ2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

323850:SHEW RS03685
gene id: 323850:SHEW_RS03685
uniprot id: A3QAU0
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

323850:SHEW RS08895
gene id: 323850:SHEW_RS08895
uniprot id: A3QDN6
names: Similarity
messages: Belongs to the globin family.

323850:SHEW RS01160
gene id: 323850:SHEW_RS01160
uniprot id: A3Q9E6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

323850:SHEW RS17020
gene id: 323850:SHEW_RS17020
uniprot id: A3QI57
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

323850:SHEW RS02810
gene id: 323850:SHEW_RS02810
uniprot id: A3QAC3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family. ParE type 1 subfamily.
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

323850:SHEW RS14615
gene id: 323850:SHEW_RS14615
uniprot id: A3QGU8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

323850:SHEW RS04550
gene id: 323850:SHEW_RS04550
uniprot id: A3QBA9
names: Domain
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cell inner membrane
messages: Homodimer.
messages: Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB/RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host.
messages: The transmembrane domain is a dimerization domain.

323850:SHEW RS12245
gene id: 323850:SHEW_RS12245
uniprot id: A3QFI1
names: Function
names: Similarity
messages: Belongs to the proline racemase family.
messages: Catalyzes the epimerization of trans-4-hydroxy-L-proline (t4LHyp) to cis-4-hydroxy-D-proline (c4DHyp). Is likely involved in a degradation pathway that converts t4LHyp to alpha-ketoglutarate. Displays no proline racemase activity.

323850:SHEW RS07910
gene id: 323850:SHEW_RS07910
uniprot id: A3QD48
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpoB family.
messages: Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division.
messages: Periplasm

323850:SHEW RS08010
gene id: 323850:SHEW_RS08010
uniprot id: A3QD60
names: Function
names: Similarity
messages: Belongs to the esterase D family.
messages: Serine hydrolase involved in the detoxification of formaldehyde.

323850:SHEW RS08255
gene id: 323850:SHEW_RS08255
uniprot id: A3QDA9
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

323850:SHEW RS00695
gene id: 323850:SHEW_RS00695
uniprot id: A3Q963
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

323850:SHEW RS00815
gene id: 323850:SHEW_RS00815
uniprot id: A3Q979
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

323850:SHEW RS14275
gene id: 323850:SHEW_RS14275
uniprot id: A3QGN2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

323850:SHEW RS11820
gene id: 323850:SHEW_RS11820
uniprot id: A3QFA1
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

323850:SHEW RS02740
gene id: 323850:SHEW_RS02740
uniprot id: A3QAA9
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

323850:SHEW RS13170
gene id: 323850:SHEW_RS13170
uniprot id: A3QG12
names: Similarity
messages: Belongs to the phosphohexose mutase family.

323850:SHEW RS19900
gene id: 323850:SHEW_RS19900
uniprot id: A3QJQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

323850:SHEW RS00435
gene id: 323850:SHEW_RS00435
uniprot id: A3Q910
names: Cofactor
names: Function
messages: Accepts electrons from ETF and reduces ubiquinone.
messages: Binds 1 [4Fe-4S] cluster.

323850:SHEW RS10420
gene id: 323850:SHEW_RS10420
uniprot id: A3QEI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell inner membrane
messages: Membrane

323850:SHEW RS02570
gene id: 323850:SHEW_RS02570
uniprot id: A3QA75
names: Similarity
messages: Belongs to the UPF0251 family.

323850:SHEW RS12860
gene id: 323850:SHEW_RS12860
uniprot id: A3QFV4
names: Similarity
messages: Belongs to the UPF0319 family.

323850:SHEW RS12800
gene id: 323850:SHEW_RS12800
uniprot id: A3QFU2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane
messages: Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins.

323850:SHEW RS12170
gene id: 323850:SHEW_RS12170
uniprot id: A3QFH1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

323850:SHEW RS04845
gene id: 323850:SHEW_RS04845
uniprot id: A3QBG5
names: Subcellular Location Annotation
messages: Membrane

323850:SHEW RS15340
gene id: 323850:SHEW_RS15340
uniprot id: A3QH80
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.
messages: Homotetramer.

323850:SHEW RS07840
gene id: 323850:SHEW_RS07840
uniprot id: A3QD34
names: Subcellular Location Annotation
messages: Membrane

323850:SHEW RS13980
gene id: 323850:SHEW_RS13980
uniprot id: A3QGH2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrF family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Cell inner membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Membrane
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway.

323850:SHEW RS10790
gene id: 323850:SHEW_RS10790
uniprot id: A3QEP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

323850:SHEW RS13095
gene id: 323850:SHEW_RS13095
uniprot id: A3QFZ8
names: Subcellular Location Annotation
messages: Membrane

323850:SHEW RS13125
gene id: 323850:SHEW_RS13125
uniprot id: A3QG03
names: Similarity
messages: Belongs to the group II decarboxylase family.

323850:SHEW RS12830
gene id: 323850:SHEW_RS12830
uniprot id: A3QFU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

323850:SHEW RS13545
gene id: 323850:SHEW_RS13545
uniprot id: A3QG85
names: Similarity
messages: Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.

323850:SHEW RS18305
gene id: 323850:SHEW_RS18305
uniprot id: A3QIV0
names: Caution
names: Similarity
messages: Belongs to the globin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

323850:SHEW RS09220
gene id: 323850:SHEW_RS09220
uniprot id: A3QDV3
names: Similarity
messages: Belongs to the band 7/mec-2 family.

323850:SHEW RS03315
gene id: 323850:SHEW_RS03315
uniprot id: A3QAL9
names: Similarity
messages: Belongs to the bacterial secretin family.

323850:SHEW RS01655
gene id: 323850:SHEW_RS01655
uniprot id: A3Q9P1
names: Function
names: Similarity
messages: Belongs to the uroporphyrinogen-III synthase family.
messages: Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.

323850:SHEW RS00900
gene id: 323850:SHEW_RS00900
uniprot id: A3Q996
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

323850:SHEW RS18175
gene id: 323850:SHEW_RS18175
uniprot id: A3QIS5
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

323850:SHEW RS14675
gene id: 323850:SHEW_RS14675
uniprot id: A3QGW0
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

323850:SHEW RS17495
gene id: 323850:SHEW_RS17495
uniprot id: A3QIF0
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

323850:SHEW RS17030
gene id: 323850:SHEW_RS17030
uniprot id: A3QI59
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

323850:SHEW RS19370
gene id: 323850:SHEW_RS19370
uniprot id: A3QJF5
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

323850:SHEW RS16680
gene id: 323850:SHEW_RS16680
uniprot id: A3QHZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

323850:SHEW RS12315
gene id: 323850:SHEW_RS12315
uniprot id: A3QFJ5
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

323850:SHEW RS07080
gene id: 323850:SHEW_RS07080
uniprot id: A3QCQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type III secretion exporter family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

323850:SHEW RS04135
gene id: 323850:SHEW_RS04135
uniprot id: A3QB25
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmC subfamily.
messages: Catalyzes the formation of 5-methyl-uridine at position 747 (m5U747) in 23S rRNA.

323850:SHEW RS00790
gene id: 323850:SHEW_RS00790
uniprot id: A3Q974
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

323850:SHEW RS00950
gene id: 323850:SHEW_RS00950
uniprot id: A3Q9A8
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

323850:SHEW RS07625
gene id: 323850:SHEW_RS07625
uniprot id: A3QCZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YejK family.
messages: nucleoid

323850:SHEW RS02620
gene id: 323850:SHEW_RS02620
uniprot id: A3QA85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
messages: Cell inner membrane

323850:SHEW RS18605
gene id: 323850:SHEW_RS18605
uniprot id: A3QJ07
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

323850:SHEW RS19350
gene id: 323850:SHEW_RS19350
uniprot id: A3QJF1
names: Similarity
messages: Belongs to the Smg family.

323850:SHEW RS12975
gene id: 323850:SHEW_RS12975
uniprot id: A3QFX7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

323850:SHEW RS05265
gene id: 323850:SHEW_RS05265
uniprot id: A3QBP3
names: Function
names: Similarity
messages: Belongs to the anhydro-N-acetylmuramic acid kinase family.
messages: Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.

323850:SHEW RS09170
gene id: 323850:SHEW_RS09170
uniprot id: A3QDU3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

323850:SHEW RS18455
gene id: 323850:SHEW_RS18455
uniprot id: A3QIY0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

323850:SHEW RS01620
gene id: 323850:SHEW_RS01620
uniprot id: A3Q9N4
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

323850:SHEW RS17395
gene id: 323850:SHEW_RS17395
uniprot id: A3QID0
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

323850:SHEW RS15370
gene id: 323850:SHEW_RS15370
uniprot id: A3QH86
names: Similarity
messages: Belongs to the GST superfamily.

323850:SHEW RS00030
gene id: 323850:SHEW_RS00030
uniprot id: A3Q8S9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

323850:SHEW RS05275
gene id: 323850:SHEW_RS05275
uniprot id: A3QBP5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

323850:SHEW RS03590
gene id: 323850:SHEW_RS03590
uniprot id: A3QAS4
names: Similarity
messages: Belongs to the pirin family.

323850:SHEW RS14155
gene id: 323850:SHEW_RS14155
uniprot id: A3QGK7
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

323850:SHEW RS04835
gene id: 323850:SHEW_RS04835
uniprot id: A3QBG3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptF/LptG family.
messages: Cell inner membrane
messages: Component of the lipopolysaccharide transport and assembly complex. The LptBFG transporter is composed of two ATP-binding proteins (LptB) and two transmembrane proteins (LptF and LptG).
messages: Membrane
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.

323850:SHEW RS18145
gene id: 323850:SHEW_RS18145
uniprot id: A3QIR9
names: Caution
names: Function
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the 2'-O methylation of guanosine at position 18 in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

323850:SHEW RS03205
gene id: 323850:SHEW_RS03205
uniprot id: A3QAJ7
names: Similarity
messages: Belongs to the PspA/IM30 family.

323850:SHEW RS04645
gene id: 323850:SHEW_RS04645
uniprot id: A3QBC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetate uptake transporter (AceTr) (TC 2.A.96) family.
messages: Membrane

323850:SHEW RS13810
gene id: 323850:SHEW_RS13810
uniprot id: A3QGD7
names: Cofactor
names: Similarity
messages: Belongs to the peptidase S45 family.
messages: Binds 1 Ca(2+) ion per dimer.

323850:SHEW RS02350
gene id: 323850:SHEW_RS02350
uniprot id: A3QA31
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SNF2/RAD54 helicase family. RapA subfamily.
messages: Interacts with the RNAP. Has a higher affinity for the core RNAP than for the holoenzyme. Its ATPase activity is stimulated by binding to RNAP.
messages: Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair.

323850:SHEW RS17525
gene id: 323850:SHEW_RS17525
uniprot id: A3QIF6
names: Subcellular Location Annotation
messages: Membrane

323850:SHEW RS03215
gene id: 323850:SHEW_RS03215
uniprot id: A3QAJ9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Cell membrane
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

323850:SHEW RS19415
gene id: 323850:SHEW_RS19415
uniprot id: A3QJG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell inner membrane
messages: Membrane

323850:SHEW RS00800
gene id: 323850:SHEW_RS00800
uniprot id: A3Q976
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

323850:SHEW RS16995
gene id: 323850:SHEW_RS16995
uniprot id: A3QI52
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

323850:SHEW RS06140
gene id: 323850:SHEW_RS06140
uniprot id: A3QC66
names: Similarity
messages: Belongs to the Gfa family.

323850:SHEW RS05360
gene id: 323850:SHEW_RS05360
uniprot id: A3QBR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm

323850:SHEW RS18045
gene id: 323850:SHEW_RS18045
uniprot id: A3QIP8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

323850:SHEW RS15120
gene id: 323850:SHEW_RS15120
uniprot id: A3QH41
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

323850:SHEW RS11710
gene id: 323850:SHEW_RS11710
uniprot id: A3QF79
names: Similarity
messages: Belongs to the YciI family.

323850:SHEW RS04385
gene id: 323850:SHEW_RS04385
uniprot id: A3QB75
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

323850:SHEW RS19915
gene id: 323850:SHEW_RS19915
uniprot id: A3QJQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

323850:SHEW RS00835
gene id: 323850:SHEW_RS00835
uniprot id: A3Q983
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

323850:SHEW RS00465
gene id: 323850:SHEW_RS00465
uniprot id: A3Q916
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

323850:SHEW RS01830
gene id: 323850:SHEW_RS01830
uniprot id: A3Q9S7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

323850:SHEW RS07810
gene id: 323850:SHEW_RS07810
uniprot id: A3QD28
names: Similarity
messages: Belongs to the asparagine synthetase family.

323850:SHEW RS00905
gene id: 323850:SHEW_RS00905
uniprot id: A3Q997
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

323850:SHEW RS05860
gene id: 323850:SHEW_RS05860
uniprot id: A3QC10
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

323850:SHEW RS12010
gene id: 323850:SHEW_RS12010
uniprot id: A3QFD9
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

323850:SHEW RS06670
gene id: 323850:SHEW_RS06670
uniprot id: A3QCH0
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

323850:SHEW RS19355
gene id: 323850:SHEW_RS19355
uniprot id: A3QJF2
names: Similarity
messages: Belongs to the DprA/Smf family.

323850:SHEW RS01530
gene id: 323850:SHEW_RS01530
uniprot id: A3Q9M0
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

323850:SHEW RS11965
gene id: 323850:SHEW_RS11965
uniprot id: A3QFD0
names: Similarity
messages: Belongs to the adrenodoxin/putidaredoxin family.

323850:SHEW RS03570
gene id: 323850:SHEW_RS03570
uniprot id: A3QAS0
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

323850:SHEW RS05010
gene id: 323850:SHEW_RS05010
uniprot id: A3QBJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

323850:SHEW RS19375
gene id: 323850:SHEW_RS19375
uniprot id: A3QJF6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Cytoplasm
messages: Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.

323850:SHEW RS18775
gene id: 323850:SHEW_RS18775
uniprot id: A3QJ41
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Cytoplasm
messages: Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
messages: Monomer.

323850:SHEW RS04790
gene id: 323850:SHEW_RS04790
uniprot id: A3QBF4
names: Similarity
messages: Belongs to the MEMO1 family.

323850:SHEW RS16175
gene id: 323850:SHEW_RS16175
uniprot id: A3QHP5
names: Similarity
messages: Belongs to the peptidase M17 family.

323850:SHEW RS11845
gene id: 323850:SHEW_RS11845
uniprot id: A3QFA6
names: Cofactor
names: Similarity
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.
messages: Binds 1 zinc ion per subunit.

323850:SHEW RS03300
gene id: 323850:SHEW_RS03300
uniprot id: A3QAL6
names: Subcellular Location Annotation
messages: Membrane

323850:SHEW RS02185
gene id: 323850:SHEW_RS02185
uniprot id: A3Q9Z8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell inner membrane
messages: Membrane

323850:SHEW RS07260
gene id: 323850:SHEW_RS07260
uniprot id: A3QCT6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. WecA subfamily.
messages: Catalyzes the transfer of the GlcNAc-1-phosphate moiety from UDP-GlcNAc onto the carrier lipid undecaprenyl phosphate (C55-P), yielding GlcNAc-pyrophosphoryl-undecaprenyl (GlcNAc-PP-C55).
messages: Cell inner membrane
messages: Membrane

323850:SHEW RS00970
gene id: 323850:SHEW_RS00970
uniprot id: A3Q9B2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmC/CycZ/HelC family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

323850:SHEW RS09440
gene id: 323850:SHEW_RS09440
uniprot id: A3QDZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

323850:SHEW RS02425
gene id: 323850:SHEW_RS02425
uniprot id: A3QA46
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

323850:SHEW RS17245
gene id: 323850:SHEW_RS17245
uniprot id: A3QIA1
names: Similarity
messages: Belongs to the SCO1/2 family.

323850:SHEW RS04840
gene id: 323850:SHEW_RS04840
uniprot id: A3QBG4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptF/LptG family.
messages: Component of the lipopolysaccharide transport and assembly complex. The LptBFG transporter is composed of two ATP-binding proteins (LptB) and two transmembrane proteins (LptF and LptG).
messages: Membrane
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.

323850:SHEW RS01430
gene id: 323850:SHEW_RS01430
uniprot id: A3Q9K0
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.

323850:SHEW RS15330
gene id: 323850:SHEW_RS15330
uniprot id: A3QH78
names: Similarity
messages: Belongs to the peptidase S8 family.

323850:SHEW RS00635
gene id: 323850:SHEW_RS00635
uniprot id: A3Q951
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

323850:SHEW RS07845
gene id: 323850:SHEW_RS07845
uniprot id: A3QD35
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.

323850:SHEW RS09615
gene id: 323850:SHEW_RS09615
uniprot id: A3QE26
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

323850:SHEW RS08550
gene id: 323850:SHEW_RS08550
uniprot id: A3QDG9
names: Similarity
messages: Belongs to the citrate synthase family.

323850:SHEW RS11625
gene id: 323850:SHEW_RS11625
uniprot id: A3QF62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

323850:SHEW RS06925
gene id: 323850:SHEW_RS06925
uniprot id: A3QCL9
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

323850:SHEW RS17120
gene id: 323850:SHEW_RS17120
uniprot id: A3QI77
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptA family.
messages: Component of the lipopolysaccharide transport and assembly complex.
messages: Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm.
messages: Periplasm

323850:SHEW RS02655
gene id: 323850:SHEW_RS02655
uniprot id: A3QA92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

323850:SHEW RS00585
gene id: 323850:SHEW_RS00585
uniprot id: A3Q941
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell inner membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.

323850:SHEW RS05580
gene id: 323850:SHEW_RS05580
uniprot id: A3QBV6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AP endonuclease 2 family.
messages: Binds 3 Zn(2+) ions.
messages: Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.

323850:SHEW RS11325
gene id: 323850:SHEW_RS11325
uniprot id: A3QF02
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MinC family.
messages: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.
messages: Interacts with MinD and FtsZ.

323850:SHEW RS00355
gene id: 323850:SHEW_RS00355
uniprot id: A3Q8Z5
names: Similarity
messages: Belongs to the iron-containing alcohol dehydrogenase family.

323850:SHEW RS13020
gene id: 323850:SHEW_RS13020
uniprot id: A3QFY3
names: Subcellular Location Annotation
messages: Membrane

323850:SHEW RS08045
gene id: 323850:SHEW_RS08045
uniprot id: A3QD67
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PSRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.

323850:SHEW RS12555
gene id: 323850:SHEW_RS12555
uniprot id: A3QFP4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. Thiolase family.
messages: Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.
messages: Cytoplasm
messages: Heterotetramer of two alpha chains (FadJ) and two beta chains (FadI).

323850:SHEW RS14580
gene id: 323850:SHEW_RS14580
uniprot id: A3QGU3
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

323850:SHEW RS07900
gene id: 323850:SHEW_RS07900
uniprot id: A3QD46
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TolB family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: Periplasm
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

323850:SHEW RS19925
gene id: 323850:SHEW_RS19925
uniprot id: A3QJR1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

323850:SHEW RS12715
gene id: 323850:SHEW_RS12715
uniprot id: A3QFS6
names: Similarity
messages: Belongs to the GST superfamily.

323850:SHEW RS13370
gene id: 323850:SHEW_RS13370
uniprot id: A3QG51
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

323850:SHEW RS11695
gene id: 323850:SHEW_RS11695
uniprot id: A3QF76
names: Similarity
messages: Belongs to the CIA30 family.

323850:SHEW RS10500
gene id: 323850:SHEW_RS10500
uniprot id: A3QEJ6
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

323850:SHEW RS18995
gene id: 323850:SHEW_RS18995
uniprot id: A3QJ85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC41A transporter family.
messages: Membrane

323850:SHEW RS05165
gene id: 323850:SHEW_RS05165
uniprot id: A3QBM3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

323850:SHEW RS06605
gene id: 323850:SHEW_RS06605
uniprot id: A3QCF7
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

323850:SHEW RS08555
gene id: 323850:SHEW_RS08555
uniprot id: A3QDH0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b560 family.
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD. The complex can form homotrimers.
messages: The heme is bound between the two transmembrane subunits.

323850:SHEW RS15150
gene id: 323850:SHEW_RS15150
uniprot id: A3QH47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

323850:SHEW RS05620
gene id: 323850:SHEW_RS05620
uniprot id: A3QBW4
names: Similarity
messages: Belongs to the XFP family.

323850:SHEW RS00330
gene id: 323850:SHEW_RS00330
uniprot id: A3Q8Z0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the formate dehydrogenase gamma subunit family.
messages: Membrane

323850:SHEW RS03220
gene id: 323850:SHEW_RS03220
uniprot id: A3QAK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0719 family.
messages: Membrane

323850:SHEW RS01070
gene id: 323850:SHEW_RS01070
uniprot id: A3Q9C8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

323850:SHEW RS05955
gene id: 323850:SHEW_RS05955
uniprot id: A3QC29
names: Similarity
messages: Belongs to the alkaline phosphatase family.

323850:SHEW RS10965
gene id: 323850:SHEW_RS10965
uniprot id: A3QES9
names: Function
names: Subunit
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease.

323850:SHEW RS14590
gene id: 323850:SHEW_RS14590
uniprot id: A3QGU5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

323850:SHEW RS09385
gene id: 323850:SHEW_RS09385
uniprot id: A3QDY2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCF family. Uup subfamily.
messages: Cytoplasm
messages: Probably plays a role in ribosome assembly or function. May be involved in resolution of branched DNA intermediates that result from template switching in postreplication gaps. Binds DNA and has ATPase activity.

323850:SHEW RS19885
gene id: 323850:SHEW_RS19885
uniprot id: A3QJQ3
names: Function
names: Similarity
messages: Belongs to the transposase 11 family.
messages: Involved in the transposition of the insertion sequence IS5.

323850:SHEW RS07545
gene id: 323850:SHEW_RS07545
uniprot id: A3QCX7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Cell inner membrane
messages: Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system).

323850:SHEW RS16005
gene id: 323850:SHEW_RS16005
uniprot id: A3QHL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

323850:SHEW RS09350
gene id: 323850:SHEW_RS09350
uniprot id: A3QDX9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ZapC family.
messages: Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ.
messages: Cytoplasm
messages: Interacts directly with FtsZ.

323850:SHEW RS13275
gene id: 323850:SHEW_RS13275
uniprot id: A3QG32
names: Similarity
messages: Belongs to the MipA/OmpV family.

323850:SHEW RS17905
gene id: 323850:SHEW_RS17905
uniprot id: A3QIM0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

323850:SHEW RS17600
gene id: 323850:SHEW_RS17600
uniprot id: A3QIH1
names: Subcellular Location Annotation
messages: Membrane

323850:SHEW RS18415
gene id: 323850:SHEW_RS18415
uniprot id: A3QIX2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Cytoplasm
messages: Oligomer of 12 subunits arranged in the form of two hexagons.

323850:SHEW RS11170
gene id: 323850:SHEW_RS11170
uniprot id: A3QEX1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

323850:SHEW RS16900
gene id: 323850:SHEW_RS16900
uniprot id: A3QI33
names: Similarity
messages: Belongs to the CutA family.

323850:SHEW RS13315
gene id: 323850:SHEW_RS13315
uniprot id: A3QG40
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

323850:SHEW RS09120
gene id: 323850:SHEW_RS09120
uniprot id: A3QDT2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.
messages: Cell membrane
messages: Heterodimer of a large and a small subunit.

323850:SHEW RS00250
gene id: 323850:SHEW_RS00250
uniprot id: A3Q8X4
names: Subcellular Location Annotation
messages: Membrane

323850:SHEW RS04075
gene id: 323850:SHEW_RS04075
uniprot id: A3QB13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

323850:SHEW RS10105
gene id: 323850:SHEW_RS10105
uniprot id: A3QEC0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Monomer.

323850:SHEW RS00845
gene id: 323850:SHEW_RS00845
uniprot id: A3Q985
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

323850:SHEW RS11910
gene id: 323850:SHEW_RS11910
uniprot id: A3QFB9
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

323850:SHEW RS08815
gene id: 323850:SHEW_RS08815
uniprot id: A3QDM0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

323850:SHEW RS14950
gene id: 323850:SHEW_RS14950
uniprot id: A3QH15
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

323850:SHEW RS07405
gene id: 323850:SHEW_RS07405
uniprot id: A3QCW4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

323850:SHEW RS18235
gene id: 323850:SHEW_RS18235
uniprot id: A3QIT7
names: Subunit
messages: Monomer.

323850:SHEW RS08315
gene id: 323850:SHEW_RS08315
uniprot id: A3QDC2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

323850:SHEW RS17925
gene id: 323850:SHEW_RS17925
uniprot id: A3QIM4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell inner membrane

323850:SHEW RS18855
gene id: 323850:SHEW_RS18855
uniprot id: A3QJ57
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

323850:SHEW RS18450
gene id: 323850:SHEW_RS18450
uniprot id: A3QIX9
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes.

323850:SHEW RS14320
gene id: 323850:SHEW_RS14320
uniprot id: A3QGP1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.

323850:SHEW RS18080
gene id: 323850:SHEW_RS18080
uniprot id: A3QIQ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.

323850:SHEW RS06960
gene id: 323850:SHEW_RS06960
uniprot id: A3QCM6
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Secreted

323850:SHEW RS12330
gene id: 323850:SHEW_RS12330
uniprot id: A3QFJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CysZ family.
messages: Cell inner membrane
messages: High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway.

323850:SHEW RS11840
gene id: 323850:SHEW_RS11840
uniprot id: A3QFA5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. GalK subfamily.
messages: Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

323850:SHEW RS08590
gene id: 323850:SHEW_RS08590
uniprot id: A3QDH7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

323850:SHEW RS02665
gene id: 323850:SHEW_RS02665
uniprot id: A3QA94
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

323850:SHEW RS09175
gene id: 323850:SHEW_RS09175
uniprot id: A3QDU4
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

323850:SHEW RS09110
gene id: 323850:SHEW_RS09110
uniprot id: A3QDT0
names: Similarity
messages: Belongs to the peptidase A31 family.

323850:SHEW RS00430
gene id: 323850:SHEW_RS00430
uniprot id: A3Q909
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

323850:SHEW RS11230
gene id: 323850:SHEW_RS11230
uniprot id: A3QEY3
names: Similarity
messages: Belongs to the glucose-6-phosphate 1-epimerase family.

323850:SHEW RS17145
gene id: 323850:SHEW_RS17145
uniprot id: A3QI82
names: Function
names: Similarity
messages: Belongs to the RapZ-like family.
messages: Displays ATPase and GTPase activities.

323850:SHEW RS03405
gene id: 323850:SHEW_RS03405
uniprot id: A3QAN7
names: Function
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

323850:SHEW RS17305
gene id: 323850:SHEW_RS17305
uniprot id: A3QIB2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

323850:SHEW RS01150
gene id: 323850:SHEW_RS01150
uniprot id: A3Q9E4
names: Function
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.
messages: Specifically catalyzes the dephosphorylation of 2-phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress.

323850:SHEW RS02920
gene id: 323850:SHEW_RS02920
uniprot id: A3QAE1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

323850:SHEW RS02275
gene id: 323850:SHEW_RS02275
uniprot id: A3QA17
names: Similarity
messages: Belongs to the formate--tetrahydrofolate ligase family.

323850:SHEW RS00915
gene id: 323850:SHEW_RS00915
uniprot id: A3Q999
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

323850:SHEW RS15480
gene id: 323850:SHEW_RS15480
uniprot id: A3QHA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

323850:SHEW RS15630
gene id: 323850:SHEW_RS15630
uniprot id: A3QHD8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PagL family.
messages: Cell outer membrane
messages: Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety.
messages: Homodimer.

323850:SHEW RS09975
gene id: 323850:SHEW_RS09975
uniprot id: A3QE96
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

323850:SHEW RS08050
gene id: 323850:SHEW_RS08050
uniprot id: A3QD68
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

323850:SHEW RS15180
gene id: 323850:SHEW_RS15180
uniprot id: A3QH53
names: Function
names: Similarity
messages: Belongs to the transpeptidase family. MrdA subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall.

323850:SHEW RS02840
gene id: 323850:SHEW_RS02840
uniprot id: A3QAC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

323850:SHEW RS09640
gene id: 323850:SHEW_RS09640
uniprot id: A3QE31
names: Similarity
messages: Belongs to the ArsC family.

323850:SHEW RS08685
gene id: 323850:SHEW_RS08685
uniprot id: A3QDJ6
names: Similarity
messages: Belongs to the peptidase M17 family.

323850:SHEW RS14290
gene id: 323850:SHEW_RS14290
uniprot id: A3QGN5
names: Similarity
messages: Belongs to the MotB family.

323850:SHEW RS18410
gene id: 323850:SHEW_RS18410
uniprot id: A3QIX1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

323850:SHEW RS14515
gene id: 323850:SHEW_RS14515
uniprot id: A3QGT0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/UDP phosphorylase family.
messages: Catalyzes the reversible phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
messages: Homohexamer; trimer of homodimers.

323850:SHEW RS13400
gene id: 323850:SHEW_RS13400
uniprot id: A3QG57
names: Similarity
messages: Belongs to the tRNA methyltransferase O family.

323850:SHEW RS14300
gene id: 323850:SHEW_RS14300
uniprot id: A3QGN7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

323850:SHEW RS04465
gene id: 323850:SHEW_RS04465
uniprot id: A3QB92
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

323850:SHEW RS09310
gene id: 323850:SHEW_RS09310
uniprot id: A3QDX1
names: Similarity
messages: Belongs to the peptidase M1 family.

323850:SHEW RS06220
gene id: 323850:SHEW_RS06220
uniprot id: A3QC83
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
messages: Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.
messages: Cytoplasm

323850:SHEW RS12340
gene id: 323850:SHEW_RS12340
uniprot id: A3QFK0
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

323850:SHEW RS06100
gene id: 323850:SHEW_RS06100
uniprot id: A3QC58
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

323850:SHEW RS16050
gene id: 323850:SHEW_RS16050
uniprot id: A3QHM1
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

323850:SHEW RS11935
gene id: 323850:SHEW_RS11935
uniprot id: A3QFC4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.

323850:SHEW RS07890
gene id: 323850:SHEW_RS07890
uniprot id: A3QD44
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbD/TolR family.
messages: Cell inner membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

323850:SHEW RS15215
gene id: 323850:SHEW_RS15215
uniprot id: A3QH60
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

323850:SHEW RS01950
gene id: 323850:SHEW_RS01950
uniprot id: A3Q9V0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CsgA/CsgB family.
messages: Fimbrium

323850:SHEW RS13995
gene id: 323850:SHEW_RS13995
uniprot id: A3QGH5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrC family.
messages: Cell inner membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

323850:SHEW RS05465
gene id: 323850:SHEW_RS05465
uniprot id: A3QBT3
names: Subcellular Location Annotation
messages: Membrane

323850:SHEW RS13590
gene id: 323850:SHEW_RS13590
uniprot id: A3QG94
names: Similarity
messages: Belongs to the skp family.

323850:SHEW RS00860
gene id: 323850:SHEW_RS00860
uniprot id: A3Q988
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

323850:SHEW RS02090
gene id: 323850:SHEW_RS02090
uniprot id: A3Q9X9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Cell inner membrane
messages: Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins.
messages: Membrane

323850:SHEW RS13600
gene id: 323850:SHEW_RS13600
uniprot id: A3QG96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

323850:SHEW RS03180
gene id: 323850:SHEW_RS03180
uniprot id: A3QAJ2
names: Similarity
messages: Belongs to the UPF0111 family.

323850:SHEW RS19470
gene id: 323850:SHEW_RS19470
uniprot id: A3QJH5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urocanase family.
messages: Binds 1 NAD(+) per subunit.
messages: Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
messages: Cytoplasm

323850:SHEW RS17785
gene id: 323850:SHEW_RS17785
uniprot id: A3QIK8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Plays an essential role in type IV pili and type II pseudopili formation by proteolytically removing the leader sequence from substrate proteins and subsequently monomethylating the alpha-amino group of the newly exposed N-terminal phenylalanine.

323850:SHEW RS16200
gene id: 323850:SHEW_RS16200
uniprot id: A3QHQ0
names: Function
names: Similarity
messages: Belongs to the HPPK family.
messages: Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.

323850:SHEW RS19950
gene id: 323850:SHEW_RS19950
uniprot id: A3QJR6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase A chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.

323850:SHEW RS10330
gene id: 323850:SHEW_RS10330
uniprot id: A3QEG6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gluconeogenesis factor family.
messages: Cytoplasm
messages: Required for morphogenesis under gluconeogenic growth conditions.

323850:SHEW RS12480
gene id: 323850:SHEW_RS12480
uniprot id: A3QFM8
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

323850:SHEW RS07195
gene id: 323850:SHEW_RS07195
uniprot id: A3QCS3
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

323850:SHEW RS18515
gene id: 323850:SHEW_RS18515
uniprot id: A3QIZ2
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

323850:SHEW RS04190
gene id: 323850:SHEW_RS04190
uniprot id: A3QB36
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

323850:SHEW RS09535
gene id: 323850:SHEW_RS09535
uniprot id: A3QE10
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

323850:SHEW RS01965
gene id: 323850:SHEW_RS01965
uniprot id: A3Q9V3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

323850:SHEW RS05445
gene id: 323850:SHEW_RS05445
uniprot id: A3QBS9
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

323850:SHEW RS11660
gene id: 323850:SHEW_RS11660
uniprot id: A3QF69
names: Cofactor
names: Similarity
messages: Belongs to the anthranilate synthase component I family.
messages: Binds 1 Mg(2+) ion per subunit.

323850:SHEW RS08575
gene id: 323850:SHEW_RS08575
uniprot id: A3QDH4
names: Function
names: Similarity
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.
messages: E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

323850:SHEW RS11465
gene id: 323850:SHEW_RS11465
uniprot id: A3QF30
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

323850:SHEW RS14625
gene id: 323850:SHEW_RS14625
uniprot id: A3QGV0
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

323850:SHEW RS18810
gene id: 323850:SHEW_RS18810
uniprot id: A3QJ48
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. Carboxylesterase BioH family.
messages: Cytoplasm
messages: Monomer.
messages: The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters.

323850:SHEW RS00515
gene id: 323850:SHEW_RS00515
uniprot id: A3Q927
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate:Na(+) symporter (ESS) (TC 2.A.27) family.
messages: Catalyzes the sodium-dependent transport of glutamate.
messages: Cell inner membrane

323850:SHEW RS11340
gene id: 323850:SHEW_RS11340
uniprot id: A3QF05
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase D family.
messages: Cytoplasm
messages: Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides.

323850:SHEW RS02085
gene id: 323850:SHEW_RS02085
uniprot id: A3Q9X8
names: Function
names: Similarity
messages: Belongs to the MreC family.
messages: Involved in formation and maintenance of cell shape.

323850:SHEW RS05225
gene id: 323850:SHEW_RS05225
uniprot id: A3QBN5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

323850:SHEW RS19955
gene id: 323850:SHEW_RS19955
uniprot id: A3QJR7
names: Subcellular Location Annotation
messages: Membrane

323850:SHEW RS06010
gene id: 323850:SHEW_RS06010
uniprot id: A3QC40
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

323850:SHEW RS11005
gene id: 323850:SHEW_RS11005
uniprot id: A3QET7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

323850:SHEW RS00865
gene id: 323850:SHEW_RS00865
uniprot id: A3Q989
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

323850:SHEW RS18680
gene id: 323850:SHEW_RS18680
uniprot id: A3QJ22
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell inner membrane
messages: Forms a membrane-associated complex with FtsE.
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in cellular division.

323850:SHEW RS15770
gene id: 323850:SHEW_RS15770
uniprot id: A3QHG6
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

323850:SHEW RS05990
gene id: 323850:SHEW_RS05990
uniprot id: A3QC36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

323850:SHEW RS11990
gene id: 323850:SHEW_RS11990
uniprot id: A3QFD5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
messages: Cytoplasm
messages: Homodimer. Forms a heterotetramer with IscU, interacts with other sulfur acceptors.
messages: Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.

323850:SHEW RS02300
gene id: 323850:SHEW_RS02300
uniprot id: A3QA22
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

323850:SHEW RS18940
gene id: 323850:SHEW_RS18940
uniprot id: A3QJ75
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

323850:SHEW RS04270
gene id: 323850:SHEW_RS04270
uniprot id: A3QB52
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

323850:SHEW RS16590
gene id: 323850:SHEW_RS16590
uniprot id: A3QHX4
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.
messages: Binds 1 [4Fe-4S] cluster.
messages: Binds 1 molybdenum-bis(molybdopterin guanine dinucleotide) (Mo-bis-MGD) cofactor per subunit.
messages: Catalytic subunit of the periplasmic nitrate reductase complex NapAB. Receives electrons from NapB and catalyzes the reduction of nitrate to nitrite.
messages: Component of the periplasmic nitrate reductase NapAB complex composed of NapA and NapB.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Periplasm
messages: Predicted to be exported by the Tat system. The position of the signal peptide cleavage has not been experimentally proven.

323850:SHEW RS14325
gene id: 323850:SHEW_RS14325
uniprot id: A3QGP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

323850:SHEW RS06165
gene id: 323850:SHEW_RS06165
uniprot id: A3QC72
names: Subcellular Location Annotation
messages: Cell inner membrane

323850:SHEW RS05935
gene id: 323850:SHEW_RS05935
uniprot id: A3QC25
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.
messages: Membrane

323850:SHEW RS07830
gene id: 323850:SHEW_RS07830
uniprot id: A3QD32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

323850:SHEW RS19085
gene id: 323850:SHEW_RS19085
uniprot id: A3QJA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

323850:SHEW RS00535
gene id: 323850:SHEW_RS00535
uniprot id: A3Q931
names: Subcellular Location Annotation
messages: Membrane

323850:SHEW RS03580
gene id: 323850:SHEW_RS03580
uniprot id: A3QAS2
names: Subcellular Location Annotation
messages: Membrane

323850:SHEW RS12885
gene id: 323850:SHEW_RS12885
uniprot id: A3QFV9
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family. L-methionine gamma-lyase subfamily.

323850:SHEW RS05660
gene id: 323850:SHEW_RS05660
uniprot id: A3QBX2
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

323850:SHEW RS03415
gene id: 323850:SHEW_RS03415
uniprot id: A3QAN9
names: Cofactor
names: Function
names: Subunit
messages: Alpha(8)-beta(8). The alpha component is a flavoprotein, the beta component is a hemoprotein.
messages: Binds 1 FAD per subunit.
messages: Binds 1 FMN per subunit.
messages: Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component.

323850:SHEW RS14450
gene id: 323850:SHEW_RS14450
uniprot id: A3QGR7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TorD/DmsD family. TorD subfamily.
messages: Cytoplasm
messages: Involved in the biogenesis of TorA. Acts on TorA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor.

323850:SHEW RS08405
gene id: 323850:SHEW_RS08405
uniprot id: A3QDE0
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

323850:SHEW RS18055
gene id: 323850:SHEW_RS18055
uniprot id: A3QIQ0
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.

323850:SHEW RS00230
gene id: 323850:SHEW_RS00230
uniprot id: A3Q8X0
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

323850:SHEW RS17190
gene id: 323850:SHEW_RS17190
uniprot id: A3QI90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EamA transporter family.
messages: Membrane

323850:SHEW RS06175
gene id: 323850:SHEW_RS06175
uniprot id: A3QC74
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

323850:SHEW RS03120
gene id: 323850:SHEW_RS03120
uniprot id: A3QAI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

323850:SHEW RS17520
gene id: 323850:SHEW_RS17520
uniprot id: A3QIF5
names: Similarity
messages: Belongs to the band 7/mec-2 family.

323850:SHEW RS14940
gene id: 323850:SHEW_RS14940
uniprot id: A3QH13
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

323850:SHEW RS00770
gene id: 323850:SHEW_RS00770
uniprot id: A3Q970
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

323850:SHEW RS15325
gene id: 323850:SHEW_RS15325
uniprot id: A3QH77
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

323850:SHEW RS04495
gene id: 323850:SHEW_RS04495
uniprot id: A3QB98
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

323850:SHEW RS12000
gene id: 323850:SHEW_RS12000
uniprot id: A3QFD7
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

323850:SHEW RS18270
gene id: 323850:SHEW_RS18270
uniprot id: A3QIU4
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

323850:SHEW RS18040
gene id: 323850:SHEW_RS18040
uniprot id: A3QIP7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

323850:SHEW RS15395
gene id: 323850:SHEW_RS15395
uniprot id: A3QH91
names: Similarity
messages: Belongs to the peptidase M13 family.

323850:SHEW RS11565
gene id: 323850:SHEW_RS11565
uniprot id: A3QF50
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Molecular chaperone. Has ATPase activity.

323850:SHEW RS14885
gene id: 323850:SHEW_RS14885
uniprot id: A3QH02
names: Subcellular Location Annotation
messages: Cytoplasm

323850:SHEW RS09180
gene id: 323850:SHEW_RS09180
uniprot id: A3QDU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell inner membrane
messages: Membrane

323850:SHEW RS14145
gene id: 323850:SHEW_RS14145
uniprot id: A3QGK5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

323850:SHEW RS13360
gene id: 323850:SHEW_RS13360
uniprot id: A3QG49
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

323850:SHEW RS17885
gene id: 323850:SHEW_RS17885
uniprot id: A3QIL6
names: Function
names: Similarity
messages: Belongs to the LpxC family.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

323850:SHEW RS07315
gene id: 323850:SHEW_RS07315
uniprot id: A3QCU6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inositol monophosphatase superfamily. CysQ family.
messages: Cell inner membrane
messages: Converts adenosine-3',5'-bisphosphate (PAP) to AMP.

323850:SHEW RS09475
gene id: 323850:SHEW_RS09475
uniprot id: A3QDZ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

323850:SHEW RS16170
gene id: 323850:SHEW_RS16170
uniprot id: A3QHP4
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

323850:SHEW RS16390
gene id: 323850:SHEW_RS16390
uniprot id: A3QHT4
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

323850:SHEW RS06170
gene id: 323850:SHEW_RS06170
uniprot id: A3QC73
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily.
messages: Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA.

323850:SHEW RS14995
gene id: 323850:SHEW_RS14995
uniprot id: A3QH24
names: Similarity
messages: Belongs to the UPF0162 family.

323850:SHEW RS00125
gene id: 323850:SHEW_RS00125
uniprot id: A3Q8U8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HemG family.
messages: Binds 1 FMN non-covalently per subunit.
messages: Catalyzes the 6-electron oxidation of protoporphyrinogen IX to form protoporphyrin IX; under anaerobic conditions uses menaquinone as an electron acceptor, under aerobic conditions uses ubiquinone as an electron acceptor.
messages: Cell inner membrane

323850:SHEW RS04090
gene id: 323850:SHEW_RS04090
uniprot id: A3QB16
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

323850:SHEW RS17455
gene id: 323850:SHEW_RS17455
uniprot id: A3QIE2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiJ family.
messages: Cytoplasm
messages: Required for ubiquinone (coenzyme Q) biosynthesis. Binds hydrophobic ubiquinone biosynthetic intermediates via its SCP2 domain and is essential for the stability of the Ubi complex. May constitute a docking platform where Ubi enzymes assemble and access their SCP2-bound polyprenyl substrates.

323850:SHEW RS20295
gene id: 323850:SHEW_RS20295
uniprot id: A3Q9V5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

323850:SHEW RS16655
gene id: 323850:SHEW_RS16655
uniprot id: A3QHY7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

323850:SHEW RS07645
gene id: 323850:SHEW_RS07645
uniprot id: A3QCZ5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

323850:SHEW RS19100
gene id: 323850:SHEW_RS19100
uniprot id: A3QJA5
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

323850:SHEW RS01520
gene id: 323850:SHEW_RS01520
uniprot id: A3Q9L8
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

323850:SHEW RS17410
gene id: 323850:SHEW_RS17410
uniprot id: A3QID3
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

323850:SHEW RS04045
gene id: 323850:SHEW_RS04045
uniprot id: A3QB07
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

323850:SHEW RS07300
gene id: 323850:SHEW_RS07300
uniprot id: A3QCU3
names: Subcellular Location Annotation
messages: Membrane

323850:SHEW RS10600
gene id: 323850:SHEW_RS10600
uniprot id: A3QEL5
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

323850:SHEW RS03985
gene id: 323850:SHEW_RS03985
uniprot id: A3QAZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbC subfamily.
messages: Periplasm
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process.

323850:SHEW RS15405
gene id: 323850:SHEW_RS15405
uniprot id: A3QH93
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

323850:SHEW RS00345
gene id: 323850:SHEW_RS00345
uniprot id: A3Q8Z3
names: Similarity
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.

323850:SHEW RS12665
gene id: 323850:SHEW_RS12665
uniprot id: A3QFR6
names: Function
names: Similarity
messages: Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.

323850:SHEW RS09505
gene id: 323850:SHEW_RS09505
uniprot id: A3QE04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

323850:SHEW RS15275
gene id: 323850:SHEW_RS15275
uniprot id: A3QH68
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

323850:SHEW RS17635
gene id: 323850:SHEW_RS17635
uniprot id: A3QIH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

323850:SHEW RS05560
gene id: 323850:SHEW_RS05560
uniprot id: A3QBV2
names: Similarity
names: Subunit
messages: Homotetramer.
messages: In the C-terminal section; belongs to the homoserine dehydrogenase family.
messages: In the N-terminal section; belongs to the aspartokinase family.

323850:SHEW RS10045
gene id: 323850:SHEW_RS10045
uniprot id: A3QEA8
names: Similarity
messages: Belongs to the asparaginase 1 family.

323850:SHEW RS00975
gene id: 323850:SHEW_RS00975
uniprot id: A3Q9B3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmB/CycW/HelB family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

323850:SHEW RS20025
gene id: 323850:SHEW_RS20025
uniprot id: A3QJT1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell inner membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

323850:SHEW RS10265
gene id: 323850:SHEW_RS10265
uniprot id: A3QEF3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Binds 1 copper ion per subunit, denoted as copper B.
messages: Binds 2 heme groups per subunit, denoted as high- and low-spin.
messages: Membrane

323850:SHEW RS05610
gene id: 323850:SHEW_RS05610
uniprot id: A3QBW2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transaldolase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

323850:SHEW RS17950
gene id: 323850:SHEW_RS17950
uniprot id: A3QIM9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

323850:SHEW RS19815
gene id: 323850:SHEW_RS19815
uniprot id: A3QJP0
names: Similarity
messages: Belongs to the AAA ATPase family.

323850:SHEW RS01865
gene id: 323850:SHEW_RS01865
uniprot id: A3Q9T4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UbiD family.
messages: Binds 1 prenylated FMN (prenyl-FMN) per subunit.
messages: Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis.
messages: Cell membrane
messages: Homohexamer.

323850:SHEW RS04035
gene id: 323850:SHEW_RS04035
uniprot id: A3QB05
names: Similarity
messages: Belongs to the peptidase S8 family.

323850:SHEW RS04995
gene id: 323850:SHEW_RS04995
uniprot id: A3QBJ5
names: Similarity
messages: Belongs to the glutamine synthetase family.

323850:SHEW RS05240
gene id: 323850:SHEW_RS05240
uniprot id: A3QBN8
names: Subcellular Location Annotation
messages: Membrane

323850:SHEW RS06015
gene id: 323850:SHEW_RS06015
uniprot id: A3QC41
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

323850:SHEW RS07400
gene id: 323850:SHEW_RS07400
uniprot id: A3QCW3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

323850:SHEW RS10115
gene id: 323850:SHEW_RS10115
uniprot id: A3QEC2
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS1 family.
messages: Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.

323850:SHEW RS14540
gene id: 323850:SHEW_RS14540
uniprot id: A3QGT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
messages: Membrane

323850:SHEW RS11715
gene id: 323850:SHEW_RS11715
uniprot id: A3QF80
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

323850:SHEW RS17155
gene id: 323850:SHEW_RS17155
uniprot id: A3QI84
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

323850:SHEW RS05005
gene id: 323850:SHEW_RS05005
uniprot id: A3QBJ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
messages: Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD).

323850:SHEW RS08185
gene id: 323850:SHEW_RS08185
uniprot id: A3QD95
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Catalyzes the deamination of dCTP to dUTP.
messages: Homotrimer.

323850:SHEW RS05650
gene id: 323850:SHEW_RS05650
uniprot id: A3QBX0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell inner membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

323850:SHEW RS11020
gene id: 323850:SHEW_RS11020
uniprot id: A3QEU0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MsrQ family.
messages: Binds 1 FMN per subunit.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Cell inner membrane
messages: Heterodimer of a catalytic subunit (MsrP) and a heme-binding subunit (MsrQ).
messages: Membrane
messages: Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain.

323850:SHEW RS12430
gene id: 323850:SHEW_RS12430
uniprot id: A3QFL8
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

323850:SHEW RS10290
gene id: 323850:SHEW_RS10290
uniprot id: A3QEF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

323850:SHEW RS00810
gene id: 323850:SHEW_RS00810
uniprot id: A3Q978
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

323850:SHEW RS17070
gene id: 323850:SHEW_RS17070
uniprot id: A3QI67
names: Similarity
messages: Belongs to the BolA/IbaG family.

323850:SHEW RS11075
gene id: 323850:SHEW_RS11075
uniprot id: A3QEV1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

323850:SHEW RS08985
gene id: 323850:SHEW_RS08985
uniprot id: A3QDQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

323850:SHEW RS18655
gene id: 323850:SHEW_RS18655
uniprot id: A3QJ17
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TPP enzyme family. MenD subfamily.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
messages: Homodimer.

323850:SHEW RS06640
gene id: 323850:SHEW_RS06640
uniprot id: A3QCG4
names: Similarity
messages: Belongs to the YfgM family.

323850:SHEW RS05805
gene id: 323850:SHEW_RS05805
uniprot id: A3QBZ9
names: Similarity
names: Subunit
messages: Belongs to the glutaminase family.
messages: Homotetramer.

323850:SHEW RS08165
gene id: 323850:SHEW_RS08165
uniprot id: A3QD91
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

323850:SHEW RS03450
gene id: 323850:SHEW_RS03450
uniprot id: A3QAP6
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

323850:SHEW RS15465
gene id: 323850:SHEW_RS15465
uniprot id: A3QHA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LysR transcriptional regulatory family.
messages: Cytoplasm

323850:SHEW RS14060
gene id: 323850:SHEW_RS14060
uniprot id: A3QGI8
names: Similarity
messages: Belongs to the peptidase S8 family.

323850:SHEW RS15300
gene id: 323850:SHEW_RS15300
uniprot id: A3QH72
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

323850:SHEW RS11105
gene id: 323850:SHEW_RS11105
uniprot id: A3QEV7
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

323850:SHEW RS05325
gene id: 323850:SHEW_RS05325
uniprot id: A3QBQ5
names: Similarity
messages: Belongs to the glutamate synthase family.

323850:SHEW RS05115
gene id: 323850:SHEW_RS05115
uniprot id: A3QBL4
names: Similarity
messages: Belongs to the site-specific recombinase resolvase family.

323850:SHEW RS14595
gene id: 323850:SHEW_RS14595
uniprot id: A3QGU6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

323850:SHEW RS03530
gene id: 323850:SHEW_RS03530
uniprot id: A3QAR2
names: Similarity
messages: Belongs to the nitroreductase family.

323850:SHEW RS12655
gene id: 323850:SHEW_RS12655
uniprot id: A3QFR4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase II family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.

323850:SHEW RS12045
gene id: 323850:SHEW_RS12045
uniprot id: A3QFE6
names: Subcellular Location Annotation
messages: Membrane

323850:SHEW RS17775
gene id: 323850:SHEW_RS17775
uniprot id: A3QIK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP E family.
messages: Cytoplasm

323850:SHEW RS00150
gene id: 323850:SHEW_RS00150
uniprot id: A3Q8V3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

323850:SHEW RS12285
gene id: 323850:SHEW_RS12285
uniprot id: A3QFI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

323850:SHEW RS19400
gene id: 323850:SHEW_RS19400
uniprot id: A3QJG1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiC family.
messages: Cytoplasm
messages: Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway.

323850:SHEW RS08930
gene id: 323850:SHEW_RS08930
uniprot id: A3QDP3
names: Subcellular Location Annotation
messages: Periplasm

323850:SHEW RS12515
gene id: 323850:SHEW_RS12515
uniprot id: A3QFN5
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmB subfamily.
messages: Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue.

323850:SHEW RS04895
gene id: 323850:SHEW_RS04895
uniprot id: A3QBH5
names: Similarity
messages: Belongs to the peptidase M24B family.

323850:SHEW RS01425
gene id: 323850:SHEW_RS01425
uniprot id: A3Q9J9
names: Subcellular Location Annotation
messages: Periplasm

323850:SHEW RS06990
gene id: 323850:SHEW_RS06990
uniprot id: A3QCN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

323850:SHEW RS01335
gene id: 323850:SHEW_RS01335
uniprot id: A3Q9I1
names: Similarity
messages: Belongs to the peptidase S9C family.

323850:SHEW RS01470
gene id: 323850:SHEW_RS01470
uniprot id: A3Q9K8
names: Subcellular Location Annotation
messages: Membrane

323850:SHEW RS10900
gene id: 323850:SHEW_RS10900
uniprot id: A3QER8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. DnaE2 subfamily.
messages: Cytoplasm
messages: DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase.

323850:SHEW RS02310
gene id: 323850:SHEW_RS02310
uniprot id: A3QA24
names: Domain
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

323850:SHEW RS10070
gene id: 323850:SHEW_RS10070
uniprot id: A3QEB3
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.

323850:SHEW RS03400
gene id: 323850:SHEW_RS03400
uniprot id: A3QAN6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNT beta subunit family.
messages: Cell inner membrane
messages: Heterodimer of an alpha and a beta chain.
messages: Membrane
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

323850:SHEW RS18335
gene id: 323850:SHEW_RS18335
uniprot id: A3QIV6
names: Similarity
messages: Belongs to the UPF0319 family.

323850:SHEW RS17890
gene id: 323850:SHEW_RS17890
uniprot id: A3QIL7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

323850:SHEW RS09970
gene id: 323850:SHEW_RS09970
uniprot id: A3QE95
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

323850:SHEW RS10700
gene id: 323850:SHEW_RS10700
uniprot id: A3QEN2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

323850:SHEW RS01745
gene id: 323850:SHEW_RS01745
uniprot id: A3Q9R0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

323850:SHEW RS18730
gene id: 323850:SHEW_RS18730
uniprot id: A3QJ32
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GSP I family.
messages: Cell inner membrane
messages: Cleaved by prepilin peptidase.
messages: Component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.
messages: Membrane
messages: Type II secretion is composed of four main components: the outer membrane complex, the inner membrane complex, the cytoplasmic secretion ATPase and the periplasm-spanning pseudopilus.

323850:SHEW RS04740
gene id: 323850:SHEW_RS04740
uniprot id: A3QBE6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

323850:SHEW RS08450
gene id: 323850:SHEW_RS08450
uniprot id: A3QDE9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

323850:SHEW RS03310
gene id: 323850:SHEW_RS03310
uniprot id: A3QAL8
names: Similarity
messages: Belongs to the GSP E family.

323850:SHEW RS09885
gene id: 323850:SHEW_RS09885
uniprot id: A3QE78
names: Similarity
messages: In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
messages: In the N-terminal section; belongs to the aldehyde dehydrogenase family.

323850:SHEW RS08605
gene id: 323850:SHEW_RS08605
uniprot id: A3QDI0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Cytoplasm
messages: Homodimer.

323850:SHEW RS15020
gene id: 323850:SHEW_RS15020
uniprot id: A3QH29
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

323850:SHEW RS05665
gene id: 323850:SHEW_RS05665
uniprot id: A3QBX3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell inner membrane
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

323850:SHEW RS13660
gene id: 323850:SHEW_RS13660
uniprot id: A3QGA8
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

323850:SHEW RS07380
gene id: 323850:SHEW_RS07380
uniprot id: A3QCV9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

323850:SHEW RS14820
gene id: 323850:SHEW_RS14820
uniprot id: A3QGY9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

323850:SHEW RS09415
gene id: 323850:SHEW_RS09415
uniprot id: A3QDY9
names: Similarity
messages: Belongs to the citrate synthase family.

323850:SHEW RS18315
gene id: 323850:SHEW_RS18315
uniprot id: A3QIV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

323850:SHEW RS18725
gene id: 323850:SHEW_RS18725
uniprot id: A3QJ31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP J family.
messages: Cell inner membrane
messages: Membrane

323850:SHEW RS00600
gene id: 323850:SHEW_RS00600
uniprot id: A3Q944
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF1 family.
messages: Cell membrane

323850:SHEW RS11885
gene id: 323850:SHEW_RS11885
uniprot id: A3QFB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

323850:SHEW RS14850
gene id: 323850:SHEW_RS14850
uniprot id: A3QGZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Membrane
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

323850:SHEW RS03075
gene id: 323850:SHEW_RS03075
uniprot id: A3QAH2
names: Similarity
messages: Belongs to the DEAD box helicase family.

323850:SHEW RS01260
gene id: 323850:SHEW_RS01260
uniprot id: A3Q9G6
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

323850:SHEW RS00210
gene id: 323850:SHEW_RS00210
uniprot id: A3Q8W5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.

323850:SHEW RS07345
gene id: 323850:SHEW_RS07345
uniprot id: A3QCV2
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

323850:SHEW RS11550
gene id: 323850:SHEW_RS11550
uniprot id: A3QF47
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

323850:SHEW RS01960
gene id: 323850:SHEW_RS01960
uniprot id: A3Q9V2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

323850:SHEW RS07705
gene id: 323850:SHEW_RS07705
uniprot id: A3QD07
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

323850:SHEW RS14845
gene id: 323850:SHEW_RS14845
uniprot id: A3QGZ4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrF family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Cell inner membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Membrane
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway.

323850:SHEW RS14305
gene id: 323850:SHEW_RS14305
uniprot id: A3QGN8
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

323850:SHEW RS06195
gene id: 323850:SHEW_RS06195
uniprot id: A3QC78
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsB family.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

323850:SHEW RS20005
gene id: 323850:SHEW_RS20005
uniprot id: A3QJS7
names: Similarity
messages: Belongs to the site-specific recombinase resolvase family.

323850:SHEW RS08490
gene id: 323850:SHEW_RS08490
uniprot id: A3QDF7
names: Subcellular Location Annotation
messages: Membrane

323850:SHEW RS08650
gene id: 323850:SHEW_RS08650
uniprot id: A3QDI9
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

323850:SHEW RS11570
gene id: 323850:SHEW_RS11570
uniprot id: A3QF51
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

323850:SHEW RS12550
gene id: 323850:SHEW_RS12550
uniprot id: A3QFP3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the formation of a hydroxyacyl-CoA by addition of water on enoyl-CoA. Also exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities.
messages: Cytoplasm
messages: Heterotetramer of two alpha chains (FadJ) and two beta chains (FadI).
messages: In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.
messages: In the central section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

323850:SHEW RS03490
gene id: 323850:SHEW_RS03490
uniprot id: A3QAQ4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

323850:SHEW RS10220
gene id: 323850:SHEW_RS10220
uniprot id: A3QEE4
names: Similarity
messages: Belongs to the peptidase S16 family.

323850:SHEW RS19200
gene id: 323850:SHEW_RS19200
uniprot id: A3QJC5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Cell inner membrane
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.

323850:SHEW RS01050
gene id: 323850:SHEW_RS01050
uniprot id: A3Q9C4
names: Function
names: Similarity
messages: Belongs to the PEPCase type 1 family.
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.

323850:SHEW RS01735
gene id: 323850:SHEW_RS01735
uniprot id: A3Q9Q8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Cell inner membrane
messages: Membrane

323850:SHEW RS01215
gene id: 323850:SHEW_RS01215
uniprot id: A3Q9F7
names: Cofactor
names: Similarity
messages: Belongs to the UPF0313 family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

323850:SHEW RS14385
gene id: 323850:SHEW_RS14385
uniprot id: A3QGQ4
names: Function
names: Similarity
messages: Belongs to the UbiT family.
messages: Required for O(2)-independent ubiquinone (coenzyme Q) biosynthesis. Likely functions as an accessory factor.

323850:SHEW RS20415
gene id: 323850:SHEW_RS20415
uniprot id: A3QEJ8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

323850:SHEW RS14530
gene id: 323850:SHEW_RS14530
uniprot id: A3QGT3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 2 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

323850:SHEW RS11330
gene id: 323850:SHEW_RS11330
uniprot id: A3QF03
names: Function
names: Similarity
names: Subunit
messages: ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.
messages: Belongs to the ParA family. MinD subfamily.
messages: Interacts with MinC and FtsZ.

323850:SHEW RS02925
gene id: 323850:SHEW_RS02925
uniprot id: A3QAE2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. HflK subfamily.
messages: HflC and HflK could encode or regulate a protease.
messages: HflC and HflK may interact to form a multimeric complex.
messages: Membrane

323850:SHEW RS02515
gene id: 323850:SHEW_RS02515
uniprot id: A3QA64
names: Function
names: Similarity
messages: Belongs to the peptidase S9C family.
messages: This enzyme catalyzes the hydrolysis of the N-terminal peptide bond of an N-acetylated peptide to generate an N-acetylated amino acid and a peptide with a free N-terminus. It preferentially cleaves off Ac-Ala, Ac-Met and Ac-Ser.

323850:SHEW RS19935
gene id: 323850:SHEW_RS19935
uniprot id: A3QJR3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase delta chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

323850:SHEW RS02850
gene id: 323850:SHEW_RS02850
uniprot id: A3QAD1
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The autoendoproteolytic cleavage occurs by a canonical serine protease mechanism, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. During this reaction, the Ser that is part of the protease active site of the proenzyme becomes the pyruvoyl prosthetic group, which constitutes an essential element of the active site of the mature decarboxylase.

323850:SHEW RS06885
gene id: 323850:SHEW_RS06885
uniprot id: A3QCL1
names: Function
names: Similarity
messages: Belongs to the FlgN family.
messages: Required for the efficient initiation of filament assembly.

323850:SHEW RS06920
gene id: 323850:SHEW_RS06920
uniprot id: A3QCL8
names: Function
names: Similarity
messages: Belongs to the FlgD family.
messages: Required for flagellar hook formation. May act as a scaffolding protein.

323850:SHEW RS16020
gene id: 323850:SHEW_RS16020
uniprot id: A3QHL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

323850:SHEW RS13585
gene id: 323850:SHEW_RS13585
uniprot id: A3QG93
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

323850:SHEW RS00935
gene id: 323850:SHEW_RS00935
uniprot id: A3Q9A5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

323850:SHEW RS03480
gene id: 323850:SHEW_RS03480
uniprot id: A3QAQ2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HemG family.
messages: Binds 1 FMN non-covalently per subunit.
messages: Catalyzes the 6-electron oxidation of protoporphyrinogen IX to form protoporphyrin IX; under anaerobic conditions uses menaquinone as an electron acceptor, under aerobic conditions uses ubiquinone as an electron acceptor.
messages: Cell inner membrane

323850:SHEW RS04490
gene id: 323850:SHEW_RS04490
uniprot id: A3QB97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThrE exporter (TC 2.A.79) family.
messages: Membrane

323850:SHEW RS16460
gene id: 323850:SHEW_RS16460
uniprot id: A3QHU8
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

323850:SHEW RS18765
gene id: 323850:SHEW_RS18765
uniprot id: A3QJ39
names: Similarity
messages: Belongs to the HSP15 family.

323850:SHEW RS14295
gene id: 323850:SHEW_RS14295
uniprot id: A3QGN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

323850:SHEW RS18125
gene id: 323850:SHEW_RS18125
uniprot id: A3QIR5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

323850:SHEW RS05180
gene id: 323850:SHEW_RS05180
uniprot id: A3QBM6
names: Function
names: Similarity
messages: Belongs to the HPPK family.
messages: Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.

323850:SHEW RS19070
gene id: 323850:SHEW_RS19070
uniprot id: A3QJ99
names: Subcellular Location Annotation
messages: Membrane

323850:SHEW RS10735
gene id: 323850:SHEW_RS10735
uniprot id: A3QEN5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.
messages: Binds 3 [4Fe-4S] clusters.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

323850:SHEW RS13645
gene id: 323850:SHEW_RS13645
uniprot id: A3QGA5
names: Activity Regulation
names: Caution
names: Domain
names: Function
names: Similarity
messages: Belongs to the GlnD family.
messages: Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism.
messages: Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity.

323850:SHEW RS01485
gene id: 323850:SHEW_RS01485
uniprot id: A3Q9L1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

323850:SHEW RS14670
gene id: 323850:SHEW_RS14670
uniprot id: A3QGV9
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

323850:SHEW RS15600
gene id: 323850:SHEW_RS15600
uniprot id: A3QHD2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

323850:SHEW RS12090
gene id: 323850:SHEW_RS12090
uniprot id: A3QFF5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

323850:SHEW RS14715
gene id: 323850:SHEW_RS14715
uniprot id: A3QGW9
names: Similarity
messages: Belongs to the peptidase M17 family.

323850:SHEW RS15165
gene id: 323850:SHEW_RS15165
uniprot id: A3QH50
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

323850:SHEW RS04245
gene id: 323850:SHEW_RS04245
uniprot id: A3QB47
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

323850:SHEW RS20315
gene id: 323850:SHEW_RS20315
uniprot id: A3QBM2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

323850:SHEW RS00840
gene id: 323850:SHEW_RS00840
uniprot id: A3Q984
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

323850:SHEW RS18645
gene id: 323850:SHEW_RS18645
uniprot id: A3QJ15
names: Subcellular Location Annotation
messages: Membrane

323850:SHEW RS16685
gene id: 323850:SHEW_RS16685
uniprot id: A3QHZ3
names: Similarity
messages: Belongs to the prokaryotic GSH synthase family.

323850:SHEW RS15595
gene id: 323850:SHEW_RS15595
uniprot id: A3QHD1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Catalyzes the sodium-dependent uptake of extracellular L-proline.
messages: Cell inner membrane
messages: Membrane

323850:SHEW RS05845
gene id: 323850:SHEW_RS05845
uniprot id: A3QC07
names: Similarity
messages: Belongs to the UPF0235 family.

323850:SHEW RS00730
gene id: 323850:SHEW_RS00730
uniprot id: A3Q965
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

323850:SHEW RS05900
gene id: 323850:SHEW_RS05900
uniprot id: A3QC18
names: Similarity
messages: Belongs to the SUI1 family.

323850:SHEW RS02495
gene id: 323850:SHEW_RS02495
uniprot id: A3QA60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

323850:SHEW RS08130
gene id: 323850:SHEW_RS08130
uniprot id: A3QD84
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

323850:SHEW RS08905
gene id: 323850:SHEW_RS08905
uniprot id: A3QDN8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

323850:SHEW RS15105
gene id: 323850:SHEW_RS15105
uniprot id: A3QH38
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

323850:SHEW RS06085
gene id: 323850:SHEW_RS06085
uniprot id: A3QC55
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

323850:SHEW RS11835
gene id: 323850:SHEW_RS11835
uniprot id: A3QFA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

323850:SHEW RS15590
gene id: 323850:SHEW_RS15590
uniprot id: A3QHD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

323850:SHEW RS11390
gene id: 323850:SHEW_RS11390
uniprot id: A3QF15
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Feedback inhibited by histidine.

323850:SHEW RS00920
gene id: 323850:SHEW_RS00920
uniprot id: A3Q9A1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

323850:SHEW RS03695
gene id: 323850:SHEW_RS03695
uniprot id: A3QAU2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Cob(I)alamin adenosyltransferase family.
messages: Cytoplasm
messages: Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids.

323850:SHEW RS16420
gene id: 323850:SHEW_RS16420
uniprot id: A3QHU0
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

323850:SHEW RS20205
gene id: 323850:SHEW_RS20205
uniprot id: A3Q924
names: Similarity
messages: Belongs to the UPF0057 (PMP3) family.

323850:SHEW RS09540
gene id: 323850:SHEW_RS09540
uniprot id: A3QE11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

323850:SHEW RS14345
gene id: 323850:SHEW_RS14345
uniprot id: A3QGP6
names: Subcellular Location Annotation
messages: Membrane

323850:SHEW RS17760
gene id: 323850:SHEW_RS17760
uniprot id: A3QIK3
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

323850:SHEW RS01575
gene id: 323850:SHEW_RS01575
uniprot id: A3Q9M9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. UvrD subfamily.
messages: Homodimer.
messages: Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replication; it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction.

323850:SHEW RS04965
gene id: 323850:SHEW_RS04965
uniprot id: A3QBI9
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

323850:SHEW RS05475
gene id: 323850:SHEW_RS05475
uniprot id: A3QBT5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

323850:SHEW RS05865
gene id: 323850:SHEW_RS05865
uniprot id: A3QC11
names: Similarity
messages: Belongs to the GSP E family.

323850:SHEW RS05495
gene id: 323850:SHEW_RS05495
uniprot id: A3QBT9
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

323850:SHEW RS16100
gene id: 323850:SHEW_RS16100
uniprot id: A3QHN0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Binds 1 FAD per subunit.
messages: Periplasm

323850:SHEW RS00170
gene id: 323850:SHEW_RS00170
uniprot id: A3Q8V7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

323850:SHEW RS08635
gene id: 323850:SHEW_RS08635
uniprot id: A3QDI6
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

323850:SHEW RS13825
gene id: 323850:SHEW_RS13825
uniprot id: A3QGE0
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

323850:SHEW RS06690
gene id: 323850:SHEW_RS06690
uniprot id: A3QCH3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: In the N-terminal section; belongs to the FGAMS family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.

323850:SHEW RS11615
gene id: 323850:SHEW_RS11615
uniprot id: A3QF60
names: Caution
names: Function
names: Similarity
messages: Belongs to the Dus family. DusC subfamily.
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U16 in tRNAs.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

323850:SHEW RS12260
gene id: 323850:SHEW_RS12260
uniprot id: A3QFI4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

323850:SHEW RS13025
gene id: 323850:SHEW_RS13025
uniprot id: A3QFY4
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

323850:SHEW RS17130
gene id: 323850:SHEW_RS17130
uniprot id: A3QI79
names: Function
names: Similarity
messages: Belongs to the sigma-54 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

323850:SHEW RS16325
gene id: 323850:SHEW_RS16325
uniprot id: A3QHS1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

323850:SHEW RS05435
gene id: 323850:SHEW_RS05435
uniprot id: A3QBS7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

323850:SHEW RS19225
gene id: 323850:SHEW_RS19225
uniprot id: A3QJD0
names: Subcellular Location Annotation
messages: Membrane

323850:SHEW RS06185
gene id: 323850:SHEW_RS06185
uniprot id: A3QC76
names: Activity Regulation
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.

323850:SHEW RS02745
gene id: 323850:SHEW_RS02745
uniprot id: A3QAB0
names: Function
names: Similarity
messages: Belongs to the Dus family. DusA subfamily.
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs.

323850:SHEW RS13570
gene id: 323850:SHEW_RS13570
uniprot id: A3QG90
names: Function
names: Similarity
messages: Belongs to the LpxB family.
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

323850:SHEW RS05655
gene id: 323850:SHEW_RS05655
uniprot id: A3QBX1
names: Function
names: Similarity
messages: Belongs to the ribF family.
messages: Catalyzes the phosphorylation of riboflavin to FMN followed by the adenylation of FMN to FAD.

323850:SHEW RS00135
gene id: 323850:SHEW_RS00135
uniprot id: A3Q8V0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HemG family.
messages: Binds 1 FMN non-covalently per subunit.
messages: Catalyzes the 6-electron oxidation of protoporphyrinogen IX to form protoporphyrin IX; under anaerobic conditions uses menaquinone as an electron acceptor, under aerobic conditions uses ubiquinone as an electron acceptor.
messages: Cell inner membrane

323850:SHEW RS03190
gene id: 323850:SHEW_RS03190
uniprot id: A3QAJ4
names: Subcellular Location Annotation
messages: Membrane

323850:SHEW RS11285
gene id: 323850:SHEW_RS11285
uniprot id: A3QEZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsbB family.
messages: Cell inner membrane
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein.

323850:SHEW RS00795
gene id: 323850:SHEW_RS00795
uniprot id: A3Q975
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

323850:SHEW RS00220
gene id: 323850:SHEW_RS00220
uniprot id: A3Q8W7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

323850:SHEW RS10915
gene id: 323850:SHEW_RS10915
uniprot id: A3QES1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

323850:SHEW RS02670
gene id: 323850:SHEW_RS02670
uniprot id: A3QA95
names: Similarity
names: Subunit
messages: Homotetramer.
messages: In the C-terminal section; belongs to the homoserine dehydrogenase family.
messages: In the N-terminal section; belongs to the aspartokinase family.

323850:SHEW RS12395
gene id: 323850:SHEW_RS12395
uniprot id: A3QFL1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

323850:SHEW RS05170
gene id: 323850:SHEW_RS05170
uniprot id: A3QBM4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell inner membrane
messages: Probably interacts with PlsX.

323850:SHEW RS00965
gene id: 323850:SHEW_RS00965
uniprot id: A3Q9B1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmD/CycX/HelD family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

323850:SHEW RS15635
gene id: 323850:SHEW_RS15635
uniprot id: A3QHD9
names: Similarity
messages: Belongs to the EndA/NucM nuclease family.

323850:SHEW RS05555
gene id: 323850:SHEW_RS05555
uniprot id: A3QBV1
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

323850:SHEW RS18955
gene id: 323850:SHEW_RS18955
uniprot id: A3QJ78
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

323850:SHEW RS10805
gene id: 323850:SHEW_RS10805
uniprot id: A3QEP9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cx-SAM synthase family.
messages: Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM).
messages: Homodimer.

323850:SHEW RS19060
gene id: 323850:SHEW_RS19060
uniprot id: A3QJ97
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell inner membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

323850:SHEW RS03385
gene id: 323850:SHEW_RS03385
uniprot id: A3QAN3
names: Function
names: Similarity
names: Subunit
messages: Catalyzes the ADP transfer from ATP to D-glycero-beta-D-manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.
messages: Catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate at the C-1 position to selectively form D-glycero-beta-D-manno-heptose-1,7-bisphosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the cytidylyltransferase family.
messages: In the N-terminal section; belongs to the carbohydrate kinase PfkB family.

323850:SHEW RS02030
gene id: 323850:SHEW_RS02030
uniprot id: A3Q9W7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell inner membrane
messages: Membrane

323850:SHEW RS05870
gene id: 323850:SHEW_RS05870
uniprot id: A3QC12
names: Similarity
messages: Belongs to the GSP E family.

323850:SHEW RS14825
gene id: 323850:SHEW_RS14825
uniprot id: A3QGZ0
names: Function
names: Similarity
messages: Belongs to the bacterioferritin family.
messages: Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.

323850:SHEW RS04725
gene id: 323850:SHEW_RS04725
uniprot id: A3QBE3
names: Subcellular Location Annotation
messages: Membrane

323850:SHEW RS17205
gene id: 323850:SHEW_RS17205
uniprot id: A3QI93
names: Subcellular Location Annotation
messages: Membrane

323850:SHEW RS04275
gene id: 323850:SHEW_RS04275
uniprot id: A3QB53
names: Subcellular Location Annotation
messages: Membrane

323850:SHEW RS19135
gene id: 323850:SHEW_RS19135
uniprot id: A3QJB2
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily.
messages: Binds 1 NADP(+) per subunit.
messages: Catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose.
messages: Contains a large N-terminal NADP-binding domain, and a smaller C-terminal substrate-binding domain.
messages: Homopentamer.

323850:SHEW RS14655
gene id: 323850:SHEW_RS14655
uniprot id: A3QGV6
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

323850:SHEW RS12390
gene id: 323850:SHEW_RS12390
uniprot id: A3QFL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0208 family.
messages: Cell inner membrane
messages: Membrane

323850:SHEW RS11470
gene id: 323850:SHEW_RS11470
uniprot id: A3QF31
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxL/LpxM/LpxP family. LpxM subfamily.
messages: Catalyzes the transfer of myristate from myristoyl-acyl carrier protein (ACP) to Kdo(2)-(lauroyl)-lipid IV(A) to form Kdo(2)-lipid A.
messages: Cell inner membrane

323850:SHEW RS11970
gene id: 323850:SHEW_RS11970
uniprot id: A3QFD1
names: Function
names: Similarity
messages: Belongs to the heat shock protein 70 family.
messages: Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB.

323850:SHEW RS13855
gene id: 323850:SHEW_RS13855
uniprot id: A3QGE6
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

323850:SHEW RS09710
gene id: 323850:SHEW_RS09710
uniprot id: A3QE45
names: Similarity
messages: Belongs to the Gfa family.

323850:SHEW RS14875
gene id: 323850:SHEW_RS14875
uniprot id: A3QH00
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LuxS family.
messages: Binds 1 Fe cation per subunit.
messages: Homodimer.
messages: Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).

323850:SHEW RS11490
gene id: 323850:SHEW_RS11490
uniprot id: A3QF35
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

323850:SHEW RS09225
gene id: 323850:SHEW_RS09225
uniprot id: A3QDV4
names: Subcellular Location Annotation
messages: Membrane

323850:SHEW RS15450
gene id: 323850:SHEW_RS15450
uniprot id: A3QHA2
names: Similarity
messages: Belongs to the glutamate synthase family.

323850:SHEW RS10760
gene id: 323850:SHEW_RS10760
uniprot id: A3QEP0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

323850:SHEW RS15365
gene id: 323850:SHEW_RS15365
uniprot id: A3QH85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

323850:SHEW RS00020
gene id: 323850:SHEW_RS00020
uniprot id: A3Q8S7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

323850:SHEW RS05500
gene id: 323850:SHEW_RS05500
uniprot id: A3QBU0
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

323850:SHEW RS18200
gene id: 323850:SHEW_RS18200
uniprot id: A3QIT0
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

323850:SHEW RS00855
gene id: 323850:SHEW_RS00855
uniprot id: A3Q987
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity).

323850:SHEW RS10110
gene id: 323850:SHEW_RS10110
uniprot id: A3QEC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

323850:SHEW RS17945
gene id: 323850:SHEW_RS17945
uniprot id: A3QIM8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsL family.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
messages: Membrane
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

323850:SHEW RS16960
gene id: 323850:SHEW_RS16960
uniprot id: A3QI45
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

323850:SHEW RS13030
gene id: 323850:SHEW_RS13030
uniprot id: A3QFY5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell inner membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

323850:SHEW RS04320
gene id: 323850:SHEW_RS04320
uniprot id: A3QB62
names: Similarity
messages: Belongs to the SlyX family.

323850:SHEW RS11450
gene id: 323850:SHEW_RS11450
uniprot id: A3QF27
names: Similarity
messages: Belongs to the peptidase S8 family.

323850:SHEW RS02915
gene id: 323850:SHEW_RS02915
uniprot id: A3QAE0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

323850:SHEW RS01465
gene id: 323850:SHEW_RS01465
uniprot id: A3Q9K7
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

323850:SHEW RS08180
gene id: 323850:SHEW_RS08180
uniprot id: A3QD94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uridine kinase family.
messages: Cytoplasm

323850:SHEW RS11790
gene id: 323850:SHEW_RS11790
uniprot id: A3QF95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

323850:SHEW RS19960
gene id: 323850:SHEW_RS19960
uniprot id: A3QJR8
names: Function
names: Similarity
messages: Belongs to the ParB family.
messages: Involved in chromosome partition. Localize to both poles of the predivisional cell following completion of DNA replication. Binds to the DNA origin of replication.

323850:SHEW RS18695
gene id: 323850:SHEW_RS18695
uniprot id: A3QJ25
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. RsmD family.
messages: Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle.

323850:SHEW RS00460
gene id: 323850:SHEW_RS00460
uniprot id: A3Q915
names: Similarity
names: Subunit
messages: Belongs to the MoaE family.
messages: Heterotetramer of 2 MoaD subunits and 2 MoaE subunits. Also stable as homodimer. The enzyme changes between these two forms during catalysis.

323850:SHEW RS15265
gene id: 323850:SHEW_RS15265
uniprot id: A3QH66
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

323850:SHEW RS05750
gene id: 323850:SHEW_RS05750
uniprot id: A3QBZ0
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

323850:SHEW RS07575
gene id: 323850:SHEW_RS07575
uniprot id: A3QCY3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
messages: Homodimer.

323850:SHEW RS07120
gene id: 323850:SHEW_RS07120
uniprot id: A3QCQ8
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

323850:SHEW RS09745
gene id: 323850:SHEW_RS09745
uniprot id: A3QE52
names: Similarity
messages: Belongs to the DEAD box helicase family.

323850:SHEW RS10000
gene id: 323850:SHEW_RS10000
uniprot id: A3QE99
names: Similarity
messages: Belongs to the YjdM family.

323850:SHEW RS06525
gene id: 323850:SHEW_RS06525
uniprot id: A3QCE1
names: Similarity
messages: Belongs to the ribosome association toxin RatA family.

323850:SHEW RS18155
gene id: 323850:SHEW_RS18155
uniprot id: A3QIS1
names: Subcellular Location Annotation
messages: Membrane

323850:SHEW RS02590
gene id: 323850:SHEW_RS02590
uniprot id: A3QA79
names: Similarity
messages: Belongs to the cytochrome c-552 family.

323850:SHEW RS13595
gene id: 323850:SHEW_RS13595
uniprot id: A3QG95
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamA family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

323850:SHEW RS10920
gene id: 323850:SHEW_RS10920
uniprot id: A3QES2
names: Subcellular Location Annotation
messages: Membrane

323850:SHEW RS04510
gene id: 323850:SHEW_RS04510
uniprot id: A3QBA1
names: Function
names: Similarity
messages: Belongs to the Ap4A hydrolase family.
messages: Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.

323850:SHEW RS01770
gene id: 323850:SHEW_RS01770
uniprot id: A3Q9R5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

323850:SHEW RS02190
gene id: 323850:SHEW_RS02190
uniprot id: A3Q9Z9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

323850:SHEW RS18005
gene id: 323850:SHEW_RS18005
uniprot id: A3QIP0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homotetramer.

323850:SHEW RS14960
gene id: 323850:SHEW_RS14960
uniprot id: A3QH17
names: Similarity
messages: Belongs to the prokaryotic GSH synthase family.

323850:SHEW RS18105
gene id: 323850:SHEW_RS18105
uniprot id: A3QIR1
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

323850:SHEW RS05940
gene id: 323850:SHEW_RS05940
uniprot id: A3QC26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

323850:SHEW RS06500
gene id: 323850:SHEW_RS06500
uniprot id: A3QCD6
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

323850:SHEW RS05400
gene id: 323850:SHEW_RS05400
uniprot id: A3QBS0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate.
messages: Cytoplasm

323850:SHEW RS02305
gene id: 323850:SHEW_RS02305
uniprot id: A3QA23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

323850:SHEW RS00805
gene id: 323850:SHEW_RS00805
uniprot id: A3Q977
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

323850:SHEW RS14575
gene id: 323850:SHEW_RS14575
uniprot id: A3QGU2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

323850:SHEW RS05565
gene id: 323850:SHEW_RS05565
uniprot id: A3QBV3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

323850:SHEW RS11035
gene id: 323850:SHEW_RS11035
uniprot id: A3QEU3
names: Similarity
messages: Belongs to the transglycosylase Slt family.

323850:SHEW RS15200
gene id: 323850:SHEW_RS15200
uniprot id: A3QH57
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

323850:SHEW RS10620
gene id: 323850:SHEW_RS10620
uniprot id: A3QEL9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

323850:SHEW RS17470
gene id: 323850:SHEW_RS17470
uniprot id: A3QIE5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatB family.
messages: Cell inner membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

323850:SHEW RS08995
gene id: 323850:SHEW_RS08995
uniprot id: A3QDQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.
messages: Membrane
messages: Required for nicotinamide riboside transport across the inner membrane.

323850:SHEW RS08140
gene id: 323850:SHEW_RS08140
uniprot id: A3QD86
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

323850:SHEW RS18050
gene id: 323850:SHEW_RS18050
uniprot id: A3QIP9
names: Similarity
messages: Belongs to the UPF0758 family.

323850:SHEW RS16710
gene id: 323850:SHEW_RS16710
uniprot id: A3QHZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methyltransferase superfamily. RsmC family.
messages: Cytoplasm
messages: Monomer.
messages: Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle.

323850:SHEW RS06155
gene id: 323850:SHEW_RS06155
uniprot id: A3QC69
names: Subcellular Location Annotation
messages: Membrane

323850:SHEW RS00930
gene id: 323850:SHEW_RS00930
uniprot id: A3Q9A4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

323850:SHEW RS19730
gene id: 323850:SHEW_RS19730
uniprot id: A3QJM6
names: Similarity
messages: Belongs to the peptidase S41A family.

323850:SHEW RS11955
gene id: 323850:SHEW_RS11955
uniprot id: A3QFC8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

323850:SHEW RS08805
gene id: 323850:SHEW_RS08805
uniprot id: A3QDL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Membrane

323850:SHEW RS11920
gene id: 323850:SHEW_RS11920
uniprot id: A3QFC1
names: Subcellular Location Annotation
messages: Membrane

323850:SHEW RS01190
gene id: 323850:SHEW_RS01190
uniprot id: A3Q9F2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

323850:SHEW RS16425
gene id: 323850:SHEW_RS16425
uniprot id: A3QHU1
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

323850:SHEW RS17870
gene id: 323850:SHEW_RS17870
uniprot id: A3QIL3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell inner membrane
messages: Cytoplasm
messages: May bind 1 zinc ion per subunit.
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

323850:SHEW RS06210
gene id: 323850:SHEW_RS06210
uniprot id: A3QC81
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruD family.
messages: Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.

323850:SHEW RS02935
gene id: 323850:SHEW_RS02935
uniprot id: A3QAE4
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The Rieske protein is a high potential 2Fe-2S protein.
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

323850:SHEW RS10770
gene id: 323850:SHEW_RS10770
uniprot id: A3QEP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

323850:SHEW RS18740
gene id: 323850:SHEW_RS18740
uniprot id: A3QJ34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP G family.
messages: Cell inner membrane
messages: Membrane

323850:SHEW RS15460
gene id: 323850:SHEW_RS15460
uniprot id: A3QHA4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 independent methionine synthase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.

323850:SHEW RS06645
gene id: 323850:SHEW_RS06645
uniprot id: A3QCG5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamB family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

323850:SHEW RS09335
gene id: 323850:SHEW_RS09335
uniprot id: A3QDX6
names: Subcellular Location Annotation
messages: Membrane

323850:SHEW RS17545
gene id: 323850:SHEW_RS17545
uniprot id: A3QIG0
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

323850:SHEW RS16505
gene id: 323850:SHEW_RS16505
uniprot id: A3QHV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDT1 family.
messages: Membrane

323850:SHEW RS12865
gene id: 323850:SHEW_RS12865
uniprot id: A3QFV5
names: Similarity
messages: Belongs to the histone deacetylase family.

323850:SHEW RS05300
gene id: 323850:SHEW_RS05300
uniprot id: A3QBQ0
names: Function
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.
messages: Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively. Also cleaves 5'-deoxyadenosine, a toxic by-product of radical S-adenosylmethionine (SAM) enzymes, into 5-deoxyribose and adenine.

323850:SHEW RS10515
gene id: 323850:SHEW_RS10515
uniprot id: A3QEK0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged L-seryl-tRNA(Thr).
messages: Cytoplasm
messages: Homodimer.

323850:SHEW RS11600
gene id: 323850:SHEW_RS11600
uniprot id: A3QF58
names: Similarity
messages: Belongs to the UPF0276 family.

323850:SHEW RS11420
gene id: 323850:SHEW_RS11420
uniprot id: A3QF21
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

323850:SHEW RS04475
gene id: 323850:SHEW_RS04475
uniprot id: A3QB94
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

323850:SHEW RS02895
gene id: 323850:SHEW_RS02895
uniprot id: A3QAD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

323850:SHEW RS13865
gene id: 323850:SHEW_RS13865
uniprot id: A3QGE8
names: Function
messages: Could be a 3Fe-4S cluster-containing protein.

323850:SHEW RS07305
gene id: 323850:SHEW_RS07305
uniprot id: A3QCU4
names: Function
names: Similarity
messages: Belongs to the APS kinase family.
messages: Catalyzes the synthesis of activated sulfate.

323850:SHEW RS19215
gene id: 323850:SHEW_RS19215
uniprot id: A3QJC8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the zinc-containing alcohol dehydrogenase family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate.
messages: Cytoplasm
messages: Homotetramer.

323850:SHEW RS01750
gene id: 323850:SHEW_RS01750
uniprot id: A3Q9R1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.

323850:SHEW RS09155
gene id: 323850:SHEW_RS09155
uniprot id: A3QDU0
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NapC/NirT/NrfH family.
messages: Binds 4 heme groups per subunit.
messages: Membrane

323850:SHEW RS01490
gene id: 323850:SHEW_RS01490
uniprot id: A3Q9L2
names: Caution
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

323850:SHEW RS00945
gene id: 323850:SHEW_RS00945
uniprot id: A3Q9A7
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

323850:SHEW RS06190
gene id: 323850:SHEW_RS06190
uniprot id: A3QC77
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

323850:SHEW RS14805
gene id: 323850:SHEW_RS14805
uniprot id: A3QGY6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

323850:SHEW RS09560
gene id: 323850:SHEW_RS09560
uniprot id: A3QE15
names: Subcellular Location Annotation
messages: Cytoplasm

323850:SHEW RS08395
gene id: 323850:SHEW_RS08395
uniprot id: A3QDD8
names: Function
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.
messages: Catalyzes the biosynthesis of agmatine from arginine.

323850:SHEW RS03420
gene id: 323850:SHEW_RS03420
uniprot id: A3QAP0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Alpha(8)-beta(8). The alpha component is a flavoprotein, the beta component is a hemoprotein.
messages: Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Binds 1 siroheme per subunit.
messages: Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate.

323850:SHEW RS11930
gene id: 323850:SHEW_RS11930
uniprot id: A3QFC3
names: Function
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.
messages: Functions in two distinct reactions of the de novo folate biosynthetic pathway. Catalyzes the addition of a glutamate residue to dihydropteroate (7,8-dihydropteroate or H2Pte) to form dihydrofolate (7,8-dihydrofolate monoglutamate or H2Pte-Glu). Also catalyzes successive additions of L-glutamate to tetrahydrofolate or 10-formyltetrahydrofolate or 5,10-methylenetetrahydrofolate, leading to folylpolyglutamate derivatives.

323850:SHEW RS05725
gene id: 323850:SHEW_RS05725
uniprot id: A3QBY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

323850:SHEW RS14600
gene id: 323850:SHEW_RS14600
uniprot id: A3QGU7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

323850:SHEW RS19775
gene id: 323850:SHEW_RS19775
uniprot id: A3QJN2
names: Caution
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
messages: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

323850:SHEW RS07385
gene id: 323850:SHEW_RS07385
uniprot id: A3QCW0
names: Subcellular Location Annotation
messages: Membrane

323850:SHEW RS07085
gene id: 323850:SHEW_RS07085
uniprot id: A3QCQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

323850:SHEW RS06120
gene id: 323850:SHEW_RS06120
uniprot id: A3QC62
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
messages: Forms an icosahedral capsid composed of 60 subunits, arranged as a dodecamer of pentamers.

323850:SHEW RS11400
gene id: 323850:SHEW_RS11400
uniprot id: A3QF17
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

323850:SHEW RS10595
gene id: 323850:SHEW_RS10595
uniprot id: A3QEL4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Catalyzes the dehydration of 6-phospho-D-gluconate to 2-dehydro-3-deoxy-6-phospho-D-gluconate.

323850:SHEW RS06025
gene id: 323850:SHEW_RS06025
uniprot id: A3QC43
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.

323850:SHEW RS09870
gene id: 323850:SHEW_RS09870
uniprot id: A3QE75
names: Similarity
messages: Belongs to the Gfa family.

323850:SHEW RS08290
gene id: 323850:SHEW_RS08290
uniprot id: A3QDB6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YceF subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes 7-methyl-GTP (m(7)GTP). May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

323850:SHEW RS18660
gene id: 323850:SHEW_RS18660
uniprot id: A3QJ18
names: Function
names: Similarity
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MenH family.
messages: Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC).
messages: Monomer.

323850:SHEW RS06005
gene id: 323850:SHEW_RS06005
uniprot id: A3QC39
names: Similarity
messages: Belongs to the disproportionating enzyme family.

323850:SHEW RS11590
gene id: 323850:SHEW_RS11590
uniprot id: A3QF55
names: Subcellular Location Annotation
messages: Cell inner membrane

323850:SHEW RS18930
gene id: 323850:SHEW_RS18930
uniprot id: A3QJ73
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

323850:SHEW RS07100
gene id: 323850:SHEW_RS07100
uniprot id: A3QCQ4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sigma-70 factor family. FliA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes.

323850:SHEW RS13330
gene id: 323850:SHEW_RS13330
uniprot id: A3QG43
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit A family.

323850:SHEW RS11705
gene id: 323850:SHEW_RS11705
uniprot id: A3QF78
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YciB family.
messages: Cell inner membrane
messages: Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.

323850:SHEW RS09305
gene id: 323850:SHEW_RS09305
uniprot id: A3QDX0
names: Similarity
messages: Belongs to the peptidase S41A family.

323850:SHEW RS05850
gene id: 323850:SHEW_RS05850
uniprot id: A3QC08
names: Similarity
messages: Belongs to the YggT family.

323850:SHEW RS07010
gene id: 323850:SHEW_RS07010
uniprot id: A3QCN6
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

323850:SHEW RS04705
gene id: 323850:SHEW_RS04705
uniprot id: A3QBD9
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

323850:SHEW RS05515
gene id: 323850:SHEW_RS05515
uniprot id: A3QBU3
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

323850:SHEW RS12325
gene id: 323850:SHEW_RS12325
uniprot id: A3QFJ7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

323850:SHEW RS06965
gene id: 323850:SHEW_RS06965
uniprot id: A3QCM7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

323850:SHEW RS14710
gene id: 323850:SHEW_RS14710
uniprot id: A3QGW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

323850:SHEW RS19920
gene id: 323850:SHEW_RS19920
uniprot id: A3QJR0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

323850:SHEW RS14755
gene id: 323850:SHEW_RS14755
uniprot id: A3QGX6
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

323850:SHEW RS14075
gene id: 323850:SHEW_RS14075
uniprot id: A3QGJ1
names: Similarity
messages: Belongs to the Nudix hydrolase family.

323850:SHEW RS08570
gene id: 323850:SHEW_RS08570
uniprot id: A3QDH3
names: Cofactor
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.

323850:SHEW RS15805
gene id: 323850:SHEW_RS15805
uniprot id: A3QHH3
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

323850:SHEW RS10395
gene id: 323850:SHEW_RS10395
uniprot id: A3QEH6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

323850:SHEW RS05815
gene id: 323850:SHEW_RS05815
uniprot id: A3QC01
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

323850:SHEW RS07205
gene id: 323850:SHEW_RS07205
uniprot id: A3QCS5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

323850:SHEW RS12845
gene id: 323850:SHEW_RS12845
uniprot id: A3QFV1
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the helicase family. DinG subfamily. Type 1 sub-subfamily.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA-dependent ATPase and 5'-3' DNA helicase.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

323850:SHEW RS05430
gene id: 323850:SHEW_RS05430
uniprot id: A3QBS6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

323850:SHEW RS02950
gene id: 323850:SHEW_RS02950
uniprot id: A3QAE7
names: Similarity
messages: Belongs to the GST superfamily. HSP26 family.

323850:SHEW RS13535
gene id: 323850:SHEW_RS13535
uniprot id: A3QG83
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

323850:SHEW RS19705
gene id: 323850:SHEW_RS19705
uniprot id: A3QJM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

323850:SHEW RS18365
gene id: 323850:SHEW_RS18365
uniprot id: A3QIW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S33 family.
messages: Cytoplasm

323850:SHEW RS08260
gene id: 323850:SHEW_RS08260
uniprot id: A3QDB0
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

323850:SHEW RS10090
gene id: 323850:SHEW_RS10090
uniprot id: A3QEB7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

323850:SHEW RS15565
gene id: 323850:SHEW_RS15565
uniprot id: A3QHC5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

323850:SHEW RS04265
gene id: 323850:SHEW_RS04265
uniprot id: A3QB51
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

323850:SHEW RS04485
gene id: 323850:SHEW_RS04485
uniprot id: A3QB96
names: Similarity
messages: Belongs to the ThrE exporter (TC 2.A.79) family.

323850:SHEW RS13010
gene id: 323850:SHEW_RS13010
uniprot id: A3QFY1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxH family.
messages: Binds 2 Mn(2+) ions per subunit in a binuclear metal center.
messages: Cell inner membrane
messages: Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

323850:SHEW RS11675
gene id: 323850:SHEW_RS11675
uniprot id: A3QF72
names: Function
names: Similarity
messages: Belongs to the TrpC family.
messages: Belongs to the TrpF family.
messages: Bifunctional enzyme that catalyzes two sequential steps of tryptophan biosynthetic pathway. The first reaction is catalyzed by the isomerase, coded by the TrpF domain; the second reaction is catalyzed by the synthase, coded by the TrpC domain.
messages: In the C-terminal section; belongs to the TrpF family.
messages: In the N-terminal section; belongs to the TrpC family.

323850:SHEW RS19465
gene id: 323850:SHEW_RS19465
uniprot id: A3QJH4
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAL/histidase family.
messages: Contains an active site 4-methylidene-imidazol-5-one (MIO), which is formed autocatalytically by cyclization and dehydration of residues Ala-Ser-Gly.
messages: Cytoplasm

323850:SHEW RS08470
gene id: 323850:SHEW_RS08470
uniprot id: A3QDF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

323850:SHEW RS10795
gene id: 323850:SHEW_RS10795
uniprot id: A3QEP7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
messages: Cytoplasm
messages: Homodimer.

323850:SHEW RS06700
gene id: 323850:SHEW_RS06700
uniprot id: A3QCH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

323850:SHEW RS14475
gene id: 323850:SHEW_RS14475
uniprot id: A3QGS2
names: Function
names: Subunit
messages: Binds the second messenger bis-(3'-5') cyclic dimeric guanosine monophosphate (c-di-GMP). Can bind two c-di-GMP molecules per monomer. May play a role in bacterial second-messenger regulated processes. Binding to c-di-GMP induces a conformational change of the C- and N-termini resulting in the exposure of a highly negative surface on one side of the protein to a possible effector protein.
messages: Monomer in both c-di-GMP-bound and free forms.

323850:SHEW RS08420
gene id: 323850:SHEW_RS08420
uniprot id: A3QDE3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

323850:SHEW RS07720
gene id: 323850:SHEW_RS07720
uniprot id: A3QD10
names: Subcellular Location Annotation
messages: Membrane

323850:SHEW RS20995
gene id: 323850:SHEW_RS20995
uniprot id: A3QBL2
names: Similarity
messages: Belongs to the MobA/MobL family.

323850:SHEW RS12600
gene id: 323850:SHEW_RS12600
uniprot id: A3QFQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Catalyzes the sodium-dependent uptake of extracellular L-proline.
messages: Cell inner membrane
messages: Membrane

323850:SHEW RS17055
gene id: 323850:SHEW_RS17055
uniprot id: A3QI64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Periplasm

323850:SHEW RS08950
gene id: 323850:SHEW_RS08950
uniprot id: A3QDP7
names: Function
messages: May be involved in the biogenesis of curli organelles.

323850:SHEW RS08585
gene id: 323850:SHEW_RS08585
uniprot id: A3QDH6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

323850:SHEW RS19890
gene id: 323850:SHEW_RS19890
uniprot id: A3QJQ4
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

323850:SHEW RS10405
gene id: 323850:SHEW_RS10405
uniprot id: A3QEH8
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

323850:SHEW RS12835
gene id: 323850:SHEW_RS12835
uniprot id: A3QFU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Gram-negative porin family.
messages: Cell outer membrane
messages: Membrane

323850:SHEW RS18130
gene id: 323850:SHEW_RS18130
uniprot id: A3QIR6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

323850:SHEW RS00310
gene id: 323850:SHEW_RS00310
uniprot id: A3Q8Y6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the formate dehydrogenase gamma subunit family.
messages: Membrane

323850:SHEW RS06200
gene id: 323850:SHEW_RS06200
uniprot id: A3QC79
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

323850:SHEW RS11980
gene id: 323850:SHEW_RS11980
uniprot id: A3QFD3
names: Similarity
messages: Belongs to the HesB/IscA family.

323850:SHEW RS06530
gene id: 323850:SHEW_RS06530
uniprot id: A3QCE2
names: Similarity
messages: Belongs to the UPF0125 (RnfH) family.

323850:SHEW RS01220
gene id: 323850:SHEW_RS01220
uniprot id: A3Q9F8
names: Subcellular Location Annotation
messages: Membrane

323850:SHEW RS01910
gene id: 323850:SHEW_RS01910
uniprot id: A3Q9U2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.
messages: Heterooctamer of two A chains, two B chains, two C chains and two D chains.
messages: Membrane

323850:SHEW RS17625
gene id: 323850:SHEW_RS17625
uniprot id: A3QIH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

323850:SHEW RS07150
gene id: 323850:SHEW_RS07150
uniprot id: A3QCR4
names: Similarity
messages: Belongs to the type III secretion exporter family.

323850:SHEW RS13575
gene id: 323850:SHEW_RS13575
uniprot id: A3QG91
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
messages: Cytoplasm
messages: Homotrimer.
messages: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

323850:SHEW RS02405
gene id: 323850:SHEW_RS02405
uniprot id: A3QA42
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

323850:SHEW RS01760
gene id: 323850:SHEW_RS01760
uniprot id: A3Q9R3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DEAD box helicase family. RhlB subfamily.
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA.

323850:SHEW RS16965
gene id: 323850:SHEW_RS16965
uniprot id: A3QI46
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins.

323850:SHEW RS14975
gene id: 323850:SHEW_RS14975
uniprot id: A3QH20
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

323850:SHEW RS09090
gene id: 323850:SHEW_RS09090
uniprot id: A3QDS6
names: Similarity
messages: Belongs to the HupF/HypC family.

323850:SHEW RS13035
gene id: 323850:SHEW_RS13035
uniprot id: A3QFY6
names: Similarity
messages: Belongs to the FeoA family.

323850:SHEW RS00120
gene id: 323850:SHEW_RS00120
uniprot id: A3Q8U7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrkH potassium transport family.
messages: Cell inner membrane
messages: Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA.
messages: Membrane

323850:SHEW RS02120
gene id: 323850:SHEW_RS02120
uniprot id: A3Q9Y5
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

323850:SHEW RS10740
gene id: 323850:SHEW_RS10740
uniprot id: A3QEN6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

323850:SHEW RS03410
gene id: 323850:SHEW_RS03410
uniprot id: A3QAN8
names: Similarity
messages: Belongs to the AlaDH/PNT family.

323850:SHEW RS08100
gene id: 323850:SHEW_RS08100
uniprot id: A3QD78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HflD family.
messages: Cell inner membrane
messages: Cytoplasm

323850:SHEW RS10165
gene id: 323850:SHEW_RS10165
uniprot id: A3QED3
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-II family.

323850:SHEW RS10685
gene id: 323850:SHEW_RS10685
uniprot id: A3QEM9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

323850:SHEW RS17715
gene id: 323850:SHEW_RS17715
uniprot id: A3QIJ4
names: Similarity
messages: Belongs to the peptidase M13 family.

323850:SHEW RS12590
gene id: 323850:SHEW_RS12590
uniprot id: A3QFQ1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

323850:SHEW RS09900
gene id: 323850:SHEW_RS09900
uniprot id: A3QE81
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 5DNU family.
messages: Catalyzes the strictly specific dephosphorylation of 2'-deoxyribonucleoside 5'-monophosphates.
messages: Cytoplasm
messages: Homodimer.

323850:SHEW RS10745
gene id: 323850:SHEW_RS10745
uniprot id: A3QEN7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

323850:SHEW RS00910
gene id: 323850:SHEW_RS00910
uniprot id: A3Q998
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

323850:SHEW RS16920
gene id: 323850:SHEW_RS16920
uniprot id: A3QI37
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

323850:SHEW RS17475
gene id: 323850:SHEW_RS17475
uniprot id: A3QIE6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

323850:SHEW RS07520
gene id: 323850:SHEW_RS07520
uniprot id: A3QCX2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

323850:SHEW RS09240
gene id: 323850:SHEW_RS09240
uniprot id: A3QDV7
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

323850:SHEW RS20215
gene id: 323850:SHEW_RS20215
uniprot id: A3Q9A0
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

323850:SHEW RS05285
gene id: 323850:SHEW_RS05285
uniprot id: A3QBP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

323850:SHEW RS06105
gene id: 323850:SHEW_RS06105
uniprot id: A3QC59
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

323850:SHEW RS10155
gene id: 323850:SHEW_RS10155
uniprot id: A3QED0
names: Similarity
messages: Belongs to the peptidase S13 family.

323850:SHEW RS12420
gene id: 323850:SHEW_RS12420
uniprot id: A3QFL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

323850:SHEW RS19335
gene id: 323850:SHEW_RS19335
uniprot id: A3QJE8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family. TsaC subfamily.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate.

323850:SHEW RS17060
gene id: 323850:SHEW_RS17060
uniprot id: A3QI65
names: Similarity
messages: Belongs to the peptidase S1C family.

323850:SHEW RS18320
gene id: 323850:SHEW_RS18320
uniprot id: A3QIV3
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

323850:SHEW RS18255
gene id: 323850:SHEW_RS18255
uniprot id: A3QIU1
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

323850:SHEW RS00650
gene id: 323850:SHEW_RS00650
uniprot id: A3Q954
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inositol monophosphatase superfamily. CysQ family.
messages: Cell inner membrane
messages: Converts adenosine-3',5'-bisphosphate (PAP) to AMP.

323850:SHEW RS12080
gene id: 323850:SHEW_RS12080
uniprot id: A3QFF3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

323850:SHEW RS09375
gene id: 323850:SHEW_RS09375
uniprot id: A3QDY0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RlmKL family.
messages: Cytoplasm
messages: Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA.

323850:SHEW RS08660
gene id: 323850:SHEW_RS08660
uniprot id: A3QDJ1
names: Similarity
messages: Belongs to the HIBADH-related family.

323850:SHEW RS11380
gene id: 323850:SHEW_RS11380
uniprot id: A3QF13
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

323850:SHEW RS10695
gene id: 323850:SHEW_RS10695
uniprot id: A3QEN1
names: Subcellular Location Annotation
messages: Membrane

323850:SHEW RS15545
gene id: 323850:SHEW_RS15545
uniprot id: A3QHC1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

323850:SHEW RS20505
gene id: 323850:SHEW_RS20505
uniprot id: A3QJT4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

323850:SHEW RS07510
gene id: 323850:SHEW_RS07510
uniprot id: A3QCX0
names: Subcellular Location Annotation
messages: Membrane

323850:SHEW RS12970
gene id: 323850:SHEW_RS12970
uniprot id: A3QFX6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

323850:SHEW RS12320
gene id: 323850:SHEW_RS12320
uniprot id: A3QFJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ZipA family.
messages: Cell inner membrane
messages: Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins.
messages: Interacts with FtsZ via their C-terminal domains.

323850:SHEW RS10730
gene id: 323850:SHEW_RS10730
uniprot id: A3QEN4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

323850:SHEW RS16835
gene id: 323850:SHEW_RS16835
uniprot id: A3QI20
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

323850:SHEW RS15640
gene id: 323850:SHEW_RS15640
uniprot id: A3QHE0
names: Subcellular Location Annotation
messages: Membrane

323850:SHEW RS07075
gene id: 323850:SHEW_RS07075
uniprot id: A3QCP9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

323850:SHEW RS11335
gene id: 323850:SHEW_RS11335
uniprot id: A3QF04
names: Function
names: Similarity
messages: Belongs to the MinE family.
messages: Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.

323850:SHEW RS05440
gene id: 323850:SHEW_RS05440
uniprot id: A3QBS8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell inner membrane
messages: Cytoplasm
messages: Monomer.

323850:SHEW RS06310
gene id: 323850:SHEW_RS06310
uniprot id: A3QC96
names: Subcellular Location Annotation
messages: Membrane

323850:SHEW RS05175
gene id: 323850:SHEW_RS05175
uniprot id: A3QBM5
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

323850:SHEW RS11180
gene id: 323850:SHEW_RS11180
uniprot id: A3QEX3
names: Cofactor
names: Similarity
messages: Belongs to the 4HPPD family.
messages: Binds 1 Fe cation per subunit.

323850:SHEW RS17650
gene id: 323850:SHEW_RS17650
uniprot id: A3QII1
names: Similarity
messages: Belongs to the GARS family.

323850:SHEW RS14680
gene id: 323850:SHEW_RS14680
uniprot id: A3QGW1
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

323850:SHEW RS08350
gene id: 323850:SHEW_RS08350
uniprot id: A3QDC9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion.
messages: Homodimer.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

323850:SHEW RS07825
gene id: 323850:SHEW_RS07825
uniprot id: A3QD31
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

323850:SHEW RS09685
gene id: 323850:SHEW_RS09685
uniprot id: A3QE40
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

323850:SHEW RS07190
gene id: 323850:SHEW_RS07190
uniprot id: A3QCS2
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

323850:SHEW RS17915
gene id: 323850:SHEW_RS17915
uniprot id: A3QIM2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. FtsW subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell division.

323850:SHEW RS05270
gene id: 323850:SHEW_RS05270
uniprot id: A3QBP4
names: Subcellular Location Annotation
messages: Membrane

323850:SHEW RS03980
gene id: 323850:SHEW_RS03980
uniprot id: A3QAZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

323850:SHEW RS03875
gene id: 323850:SHEW_RS03875
uniprot id: A3QAX7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. Epd subfamily.
messages: Catalyzes the NAD-dependent conversion of D-erythrose 4-phosphate to 4-phosphoerythronate.
messages: Cytoplasm
messages: Homotetramer.

323850:SHEW RS20220
gene id: 323850:SHEW_RS20220
uniprot id: A3Q9A3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

323850:SHEW RS17015
gene id: 323850:SHEW_RS17015
uniprot id: A3QI56
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. RlmB subfamily.
messages: Cytoplasm
messages: Specifically methylates the ribose of guanosine 2251 in 23S rRNA.

323850:SHEW RS10570
gene id: 323850:SHEW_RS10570
uniprot id: A3QEK9
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

323850:SHEW RS10615
gene id: 323850:SHEW_RS10615
uniprot id: A3QEL8
names: Similarity
messages: Belongs to the pyruvate kinase family.

323850:SHEW RS13350
gene id: 323850:SHEW_RS13350
uniprot id: A3QG47
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.

323850:SHEW RS18690
gene id: 323850:SHEW_RS18690
uniprot id: A3QJ24
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell inner membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

323850:SHEW RS17535
gene id: 323850:SHEW_RS17535
uniprot id: A3QIF8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PNP/UDP phosphorylase family.
messages: Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis.
messages: Cytoplasm

323850:SHEW RS01375
gene id: 323850:SHEW_RS01375
uniprot id: A3Q9I9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbA subfamily.
messages: Periplasm

323850:SHEW RS06890
gene id: 323850:SHEW_RS06890
uniprot id: A3QCL2
names: Function
names: Similarity
messages: Belongs to the FlgM family.
messages: Responsible for the coupling of flagellin expression to flagellar assembly by preventing expression of the flagellin genes when a component of the middle class of proteins is defective. It negatively regulates flagellar genes by inhibiting the activity of FliA by directly binding to FliA.

323850:SHEW RS01550
gene id: 323850:SHEW_RS01550
uniprot id: A3Q9M4
names: Subcellular Location Annotation
messages: Membrane

323850:SHEW RS11030
gene id: 323850:SHEW_RS11030
uniprot id: A3QEU2
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

323850:SHEW RS00455
gene id: 323850:SHEW_RS00455
uniprot id: A3Q914
names: Similarity
messages: Belongs to the MoaD family.

323850:SHEW RS13985
gene id: 323850:SHEW_RS13985
uniprot id: A3QGH3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Membrane
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

323850:SHEW RS05375
gene id: 323850:SHEW_RS05375
uniprot id: A3QBR5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

323850:SHEW RS02595
gene id: 323850:SHEW_RS02595
uniprot id: A3QA80
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

323850:SHEW RS14830
gene id: 323850:SHEW_RS14830
uniprot id: A3QGZ1
names: Function
names: Similarity
messages: Belongs to the bacterioferritin family.
messages: Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.

323850:SHEW RS14860
gene id: 323850:SHEW_RS14860
uniprot id: A3QGZ7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrC family.
messages: Cell inner membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

323850:SHEW RS15505
gene id: 323850:SHEW_RS15505
uniprot id: A3QHB3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane
messages: Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

323850:SHEW RS11580
gene id: 323850:SHEW_RS11580
uniprot id: A3QF53
names: Similarity
messages: Belongs to the DnaX/STICHEL family.

323850:SHEW RS06970
gene id: 323850:SHEW_RS06970
uniprot id: A3QCM8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

323850:SHEW RS14445
gene id: 323850:SHEW_RS14445
uniprot id: A3QGR6
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
messages: Binds 1 molybdenum-bis(molybdopterin guanine dinucleotide) (Mo-bis-MGD) cofactor per subunit.
messages: Exported by the Tat system.
messages: Periplasm
messages: Reduces trimethylamine-N-oxide (TMAO) into trimethylamine; an anaerobic reaction coupled to energy-yielding reactions.

323850:SHEW RS00115
gene id: 323850:SHEW_RS00115
uniprot id: A3Q8U6
names: Similarity
messages: Belongs to the IMPACT family.

323850:SHEW RS13730
gene id: 323850:SHEW_RS13730
uniprot id: A3QGC1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Syd family.
messages: Cell inner membrane
messages: Interacts with the SecY protein in vivo. May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function.

323850:SHEW RS13800
gene id: 323850:SHEW_RS13800
uniprot id: A3QGD5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thioester dehydratase family. FabA subfamily.
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Cytoplasm
messages: Homodimer.

323850:SHEW RS06980
gene id: 323850:SHEW_RS06980
uniprot id: A3QCN0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum
messages: Belongs to the FliD family.
messages: Homopentamer.
messages: Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Secreted

323850:SHEW RS15875
gene id: 323850:SHEW_RS15875
uniprot id: A3QHI6
names: Function
names: Similarity
names: Subunit
messages: Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division.
messages: Belongs to the ZapA family. Type 1 subfamily.
messages: Homodimer. Interacts with FtsZ.

323850:SHEW RS09605
gene id: 323850:SHEW_RS09605
uniprot id: A3QE24
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO8N (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in the Shewanella genus.
messages: Belongs to the KdsB family.
messages: Cytoplasm

323850:SHEW RS19395
gene id: 323850:SHEW_RS19395
uniprot id: A3QJG0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell inner membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

323850:SHEW RS06635
gene id: 323850:SHEW_RS06635
uniprot id: A3QCG3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

323850:SHEW RS19050
gene id: 323850:SHEW_RS19050
uniprot id: A3QJ95
names: Function
names: Similarity
messages: Belongs to the isochorismate synthase family.
messages: Catalyzes the conversion of chorismate to isochorismate.

323850:SHEW RS08595
gene id: 323850:SHEW_RS08595
uniprot id: A3QDH8
names: Similarity
messages: Belongs to the glutamate synthase family.

323850:SHEW RS07880
gene id: 323850:SHEW_RS07880
uniprot id: A3QD42
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

323850:SHEW RS04365
gene id: 323850:SHEW_RS04365
uniprot id: A3QB71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Membrane

323850:SHEW RS05415
gene id: 323850:SHEW_RS05415
uniprot id: A3QBS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RseB family.
messages: Periplasm

323850:SHEW RS08125
gene id: 323850:SHEW_RS08125
uniprot id: A3QD83
names: Subcellular Location Annotation
messages: Cytoplasm

323850:SHEW RS19270
gene id: 323850:SHEW_RS19270
uniprot id: A3QJD9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine.

323850:SHEW RS01920
gene id: 323850:SHEW_RS01920
uniprot id: A3Q9U4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell inner membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.

323850:SHEW RS05405
gene id: 323850:SHEW_RS05405
uniprot id: A3QBS1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

323850:SHEW RS12815
gene id: 323850:SHEW_RS12815
uniprot id: A3QFU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

323850:SHEW RS01850
gene id: 323850:SHEW_RS01850
uniprot id: A3Q9T1
names: Subcellular Location Annotation
messages: Membrane

323850:SHEW RS17975
gene id: 323850:SHEW_RS17975
uniprot id: A3QIN4
names: Activity Regulation
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.

323850:SHEW RS07060
gene id: 323850:SHEW_RS07060
uniprot id: A3QCP6
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliO/MopB family.
messages: Cell membrane

323850:SHEW RS13765
gene id: 323850:SHEW_RS13765
uniprot id: A3QGC8
names: Subcellular Location Annotation
messages: Membrane

323850:SHEW RS13840
gene id: 323850:SHEW_RS13840
uniprot id: A3QGE3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

323850:SHEW RS15845
gene id: 323850:SHEW_RS15845
uniprot id: A3QHI1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

323850:SHEW RS16510
gene id: 323850:SHEW_RS16510
uniprot id: A3QHV8
names: Similarity
messages: Belongs to the catalase family.

323850:SHEW RS08495
gene id: 323850:SHEW_RS08495
uniprot id: A3QDF8
names: Function
names: Similarity
messages: Belongs to the LpxK family.
messages: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

323850:SHEW RS07200
gene id: 323850:SHEW_RS07200
uniprot id: A3QCS4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

323850:SHEW RS03675
gene id: 323850:SHEW_RS03675
uniprot id: A3QAT8
names: Function
names: Similarity
messages: Belongs to the CobT family.
messages: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).

323850:SHEW RS02115
gene id: 323850:SHEW_RS02115
uniprot id: A3Q9Y4
names: Similarity
messages: Belongs to the peptidase U62 family.

323850:SHEW RS08235
gene id: 323850:SHEW_RS08235
uniprot id: A3QDA5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of sn-l,2-diacylglycerol (DAG) to phosphatidic acid. Involved in the recycling of diacylglycerol produced as a by-product during membrane-derived oligosaccharide (MDO) biosynthesis.
messages: Cell inner membrane
messages: Membrane

323850:SHEW RS11175
gene id: 323850:SHEW_RS11175
uniprot id: A3QEX2
names: Similarity
messages: Belongs to the homogentisate dioxygenase family.

323850:SHEW RS06935
gene id: 323850:SHEW_RS06935
uniprot id: A3QCM1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

323850:SHEW RS10985
gene id: 323850:SHEW_RS10985
uniprot id: A3QET3
names: Similarity
messages: Belongs to the transglycosylase Slt family.

323850:SHEW RS02630
gene id: 323850:SHEW_RS02630
uniprot id: A3QA87
names: Subcellular Location Annotation
messages: Membrane

323850:SHEW RS13000
gene id: 323850:SHEW_RS13000
uniprot id: A3QFX9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

323850:SHEW RS13235
gene id: 323850:SHEW_RS13235
uniprot id: A3QG24
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

323850:SHEW RS02660
gene id: 323850:SHEW_RS02660
uniprot id: A3QA93
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MetJ family.
messages: Cytoplasm
messages: Homodimer.

323850:SHEW RS10365
gene id: 323850:SHEW_RS10365
uniprot id: A3QEH0
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

323850:SHEW RS19930
gene id: 323850:SHEW_RS19930
uniprot id: A3QJR2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

323850:SHEW RS04335
gene id: 323850:SHEW_RS04335
uniprot id: A3QB65
names: Similarity
messages: Belongs to the UPF0231 family.

323850:SHEW RS04255
gene id: 323850:SHEW_RS04255
uniprot id: A3QB49
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
messages: Homodimer.

323850:SHEW RS01130
gene id: 323850:SHEW_RS01130
uniprot id: A3Q9E0
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

323850:SHEW RS18900
gene id: 323850:SHEW_RS18900
uniprot id: A3QJ66
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RlmJ family.
messages: Monomer.
messages: Specifically methylates the adenine in position 2030 of 23S rRNA.

323850:SHEW RS17460
gene id: 323850:SHEW_RS17460
uniprot id: A3QIE3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC1 family. UbiB subfamily.
messages: Cell inner membrane
messages: Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis.

323850:SHEW RS09665
gene id: 323850:SHEW_RS09665
uniprot id: A3QE36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

323850:SHEW RS16540
gene id: 323850:SHEW_RS16540
uniprot id: A3QHW4
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

323850:SHEW RS09465
gene id: 323850:SHEW_RS09465
uniprot id: A3QDZ6
names: Similarity
messages: Belongs to the YkuD family.

323850:SHEW RS01145
gene id: 323850:SHEW_RS01145
uniprot id: A3Q9E3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

323850:SHEW RS08955
gene id: 323850:SHEW_RS08955
uniprot id: A3QDP8
names: Function
names: Similarity
messages: Belongs to the CsgG family.
messages: May be involved in the biogenesis of curli organelles.

323850:SHEW RS04350
gene id: 323850:SHEW_RS04350
uniprot id: A3QB68
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c-552 family.
messages: Binds 1 Ca(2+) ion per monomer.
messages: Binds 5 heme c groups covalently per monomer.
messages: Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process.
messages: Periplasm

323850:SHEW RS08370
gene id: 323850:SHEW_RS08370
uniprot id: A3QDD3
names: Subcellular Location Annotation
messages: Cytoplasm

323850:SHEW RS10580
gene id: 323850:SHEW_RS10580
uniprot id: A3QEL1
names: Subcellular Location Annotation
messages: Membrane

323850:SHEW RS07885
gene id: 323850:SHEW_RS07885
uniprot id: A3QD43
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbB/TolQ family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

323850:SHEW RS00590
gene id: 323850:SHEW_RS00590
uniprot id: A3Q942
names: Subcellular Location Annotation
messages: Membrane

323850:SHEW RS10585
gene id: 323850:SHEW_RS10585
uniprot id: A3QEL2
names: Similarity
messages: Belongs to the protease inhibitor I11 (ecotin) family.

323850:SHEW RS14050
gene id: 323850:SHEW_RS14050
uniprot id: A3QGI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

323850:SHEW RS03130
gene id: 323850:SHEW_RS03130
uniprot id: A3QAI2
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

323850:SHEW RS12360
gene id: 323850:SHEW_RS12360
uniprot id: A3QFK4
names: Subcellular Location Annotation
messages: Membrane

323850:SHEW RS16035
gene id: 323850:SHEW_RS16035
uniprot id: A3QHL8
names: Similarity
messages: Belongs to the universal stress protein A family.

323850:SHEW RS00580
gene id: 323850:SHEW_RS00580
uniprot id: A3Q940
names: Similarity
messages: Belongs to the SCO1/2 family.

323850:SHEW RS08325
gene id: 323850:SHEW_RS08325
uniprot id: A3QDC4
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

323850:SHEW RS00235
gene id: 323850:SHEW_RS00235
uniprot id: A3Q8X1
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

323850:SHEW RS01940
gene id: 323850:SHEW_RS01940
uniprot id: A3Q9U8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

323850:SHEW RS08425
gene id: 323850:SHEW_RS08425
uniprot id: A3QDE4
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

323850:SHEW RS11575
gene id: 323850:SHEW_RS11575
uniprot id: A3QF52
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

323850:SHEW RS11915
gene id: 323850:SHEW_RS11915
uniprot id: A3QFC0
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

323850:SHEW RS00470
gene id: 323850:SHEW_RS00470
uniprot id: A3Q917
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

323850:SHEW RS04630
gene id: 323850:SHEW_RS04630
uniprot id: A3QBC4
names: Function
messages: E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

323850:SHEW RS09485
gene id: 323850:SHEW_RS09485
uniprot id: A3QE00
names: Similarity
messages: Belongs to the UPF0229 family.

323850:SHEW RS03655
gene id: 323850:SHEW_RS03655
uniprot id: A3QAT4
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

323850:SHEW RS07030
gene id: 323850:SHEW_RS07030
uniprot id: A3QCP0
names: Subcellular Location Annotation
messages: Cytoplasm

323850:SHEW RS01075
gene id: 323850:SHEW_RS01075
uniprot id: A3Q9C9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.

323850:SHEW RS18060
gene id: 323850:SHEW_RS18060
uniprot id: A3QIQ1
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

323850:SHEW RS16430
gene id: 323850:SHEW_RS16430
uniprot id: A3QHU2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

323850:SHEW RS06915
gene id: 323850:SHEW_RS06915
uniprot id: A3QCL7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

323850:SHEW RS17795
gene id: 323850:SHEW_RS17795
uniprot id: A3QIL0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ZapD family.
messages: Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity.
messages: Cytoplasm
messages: Interacts with FtsZ.

323850:SHEW RS19905
gene id: 323850:SHEW_RS19905
uniprot id: A3QJQ7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.

323850:SHEW RS15605
gene id: 323850:SHEW_RS15605
uniprot id: A3QHD3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

323850:SHEW RS01730
gene id: 323850:SHEW_RS01730
uniprot id: A3Q9Q7
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: The fumarate reductase enzyme complex is required for fumarate respiration. This subunit anchors the complex in the membrane and binds a diheme cytochrome b.

323850:SHEW RS07455
gene id: 323850:SHEW_RS07455
uniprot id: A3QCW8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Monomer.

323850:SHEW RS09570
gene id: 323850:SHEW_RS09570
uniprot id: A3QE17
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamC family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

323850:SHEW RS10310
gene id: 323850:SHEW_RS10310
uniprot id: A3QEG2
names: Similarity
messages: Belongs to the universal stress protein A family.

323850:SHEW RS14585
gene id: 323850:SHEW_RS14585
uniprot id: A3QGU4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

323850:SHEW RS01120
gene id: 323850:SHEW_RS01120
uniprot id: A3Q9D8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm

323850:SHEW RS09115
gene id: 323850:SHEW_RS09115
uniprot id: A3QDT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HupC/HyaC/HydC family.
messages: Membrane

323850:SHEW RS02930
gene id: 323850:SHEW_RS02930
uniprot id: A3QAE3
names: Function
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflC subfamily.
messages: HflC and HflK could regulate a protease.

323850:SHEW RS09795
gene id: 323850:SHEW_RS09795
uniprot id: A3QE61
names: Similarity
messages: Belongs to the UPF0047 family.

323850:SHEW RS12850
gene id: 323850:SHEW_RS12850
uniprot id: A3QFV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

323850:SHEW RS00940
gene id: 323850:SHEW_RS00940
uniprot id: A3Q9A6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

323850:SHEW RS03365
gene id: 323850:SHEW_RS03365
uniprot id: A3QAM9
names: Similarity
messages: Belongs to the peptidase M16 family.

323850:SHEW RS13850
gene id: 323850:SHEW_RS13850
uniprot id: A3QGE5
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

323850:SHEW RS09620
gene id: 323850:SHEW_RS09620
uniprot id: A3QE27
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

323850:SHEW RS12805
gene id: 323850:SHEW_RS12805
uniprot id: A3QFU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

323850:SHEW RS02905
gene id: 323850:SHEW_RS02905
uniprot id: A3QAD8
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

323850:SHEW RS13120
gene id: 323850:SHEW_RS13120
uniprot id: A3QG02
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

323850:SHEW RS18675
gene id: 323850:SHEW_RS18675
uniprot id: A3QJ21
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoH subfamily.
messages: Cytoplasm
messages: Interacts with the RNA polymerase core enzyme.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.

323850:SHEW RS12365
gene id: 323850:SHEW_RS12365
uniprot id: A3QFK5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

323850:SHEW RS01085
gene id: 323850:SHEW_RS01085
uniprot id: A3Q9D1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.
messages: Membrane

323850:SHEW RS03495
gene id: 323850:SHEW_RS03495
uniprot id: A3QAQ5
names: Similarity
messages: Belongs to the peptidase C59 family.

323850:SHEW RS18355
gene id: 323850:SHEW_RS18355
uniprot id: A3QIW0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

323850:SHEW RS13500
gene id: 323850:SHEW_RS13500
uniprot id: A3QG76
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

323850:SHEW RS00830
gene id: 323850:SHEW_RS00830
uniprot id: A3Q982
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: Methylated by PrmB.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

323850:SHEW RS10355
gene id: 323850:SHEW_RS10355
uniprot id: A3QEG8
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

323850:SHEW RS17375
gene id: 323850:SHEW_RS17375
uniprot id: A3QIC6
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

323850:SHEW RS06205
gene id: 323850:SHEW_RS06205
uniprot id: A3QC80
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).

323850:SHEW RS00740
gene id: 323850:SHEW_RS00740
uniprot id: A3Q967
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic pantothenate kinase family.
messages: Cytoplasm

323850:SHEW RS20330
gene id: 323850:SHEW_RS20330
uniprot id: A3QC90
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s).
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

323850:SHEW RS10150
gene id: 323850:SHEW_RS10150
uniprot id: A3QEC9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

323850:SHEW RS12075
gene id: 323850:SHEW_RS12075
uniprot id: A3QFF2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.