319795:DGEO RS12205
gene id: 319795:DGEO_RS12205
uniprot id: Q1IX51
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

319795:DGEO RS03765
gene id: 319795:DGEO_RS03765
uniprot id: Q1J1U8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

319795:DGEO RS02935
gene id: 319795:DGEO_RS02935
uniprot id: Q1J2B1
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

319795:DGEO RS13035
gene id: 319795:DGEO_RS13035
uniprot id: Q1IWP3
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit.

319795:DGEO RS15390
gene id: 319795:DGEO_RS15390
uniprot id: A8ZR47
names: Function
messages: Involved in the transposition of the insertion sequence.

319795:DGEO RS11715
gene id: 319795:DGEO_RS11715
uniprot id: Q1IXE5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
messages: Homotetramer.

319795:DGEO RS06620
gene id: 319795:DGEO_RS06620
uniprot id: Q1J0A0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Lacks the C-terminal regulatory region which is replaced by HisZ.

319795:DGEO RS01365
gene id: 319795:DGEO_RS01365
uniprot id: Q1J2X1
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAL/histidase family.
messages: Contains an active site 4-methylidene-imidazol-5-one (MIO), which is formed autocatalytically by cyclization and dehydration of residues Ala-Ser-Gly.
messages: Cytoplasm

319795:DGEO RS03595
gene id: 319795:DGEO_RS03595
uniprot id: Q1J1Y3
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

319795:DGEO RS09040
gene id: 319795:DGEO_RS09040
uniprot id: Q1IYW5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

319795:DGEO RS06260
gene id: 319795:DGEO_RS06260
uniprot id: Q1J0H2
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

319795:DGEO RS13040
gene id: 319795:DGEO_RS13040
uniprot id: Q1IWP2
names: Similarity
messages: Belongs to the V-ATPase F subunit family.

319795:DGEO RS05800
gene id: 319795:DGEO_RS05800
uniprot id: Q1J0Q9
names: Cofactor
names: Function
messages: Binds 2 [4Fe-4S] clusters.
messages: Component of a complex that catalyzes the oxidation of glycolate to glyoxylate.

319795:DGEO RS12045
gene id: 319795:DGEO_RS12045
uniprot id: Q1IX82
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

319795:DGEO RS08715
gene id: 319795:DGEO_RS08715
uniprot id: Q1IZ31
names: Subcellular Location Annotation
messages: Membrane

319795:DGEO RS07930
gene id: 319795:DGEO_RS07930
uniprot id: Q1IZJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

319795:DGEO RS02990
gene id: 319795:DGEO_RS02990
uniprot id: Q1J2A0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.

319795:DGEO RS01460
gene id: 319795:DGEO_RS01460
uniprot id: Q1J2Z0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

319795:DGEO RS01235
gene id: 319795:DGEO_RS01235
uniprot id: Q1J2U5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

319795:DGEO RS08920
gene id: 319795:DGEO_RS08920
uniprot id: Q1IYY9
names: Function
names: Similarity
messages: Belongs to the CcmH/CycL/Ccl2/NrfF family.
messages: Possible subunit of a heme lyase.

319795:DGEO RS02290
gene id: 319795:DGEO_RS02290
uniprot id: Q1J3G1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0014 family.
messages: Membrane

319795:DGEO RS02645
gene id: 319795:DGEO_RS02645
uniprot id: Q1J2G8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

319795:DGEO RS05670
gene id: 319795:DGEO_RS05670
uniprot id: Q1J0T4
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

319795:DGEO RS00105
gene id: 319795:DGEO_RS00105
uniprot id: Q1J3P1
names: Subcellular Location Annotation
messages: Membrane

319795:DGEO RS02250
gene id: 319795:DGEO_RS02250
uniprot id: Q1J3F3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArsB family.
messages: Cell membrane
messages: Involved in arsenical resistance. Thought to form the channel of an arsenite pump.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

319795:DGEO RS13495
gene id: 319795:DGEO_RS13495
uniprot id: Q1IWF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

319795:DGEO RS01650
gene id: 319795:DGEO_RS01650
uniprot id: Q1J330
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

319795:DGEO RS06595
gene id: 319795:DGEO_RS06595
uniprot id: Q1J0A5
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

319795:DGEO RS07520
gene id: 319795:DGEO_RS07520
uniprot id: Q1IZS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CRISPR system Cmr5 family.
messages: Cytoplasm

319795:DGEO RS14040
gene id: 319795:DGEO_RS14040
uniprot id: Q1IW46
names: Subcellular Location Annotation
messages: Membrane

319795:DGEO RS00730
gene id: 319795:DGEO_RS00730
uniprot id: Q1J2J4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

319795:DGEO RS07970
gene id: 319795:DGEO_RS07970
uniprot id: Q1IZI0
names: Similarity
messages: Belongs to the ribonuclease N1/T1 family.

319795:DGEO RS07605
gene id: 319795:DGEO_RS07605
uniprot id: Q1IZQ6
names: Similarity
messages: Belongs to the peptidase S8 family.

319795:DGEO RS11415
gene id: 319795:DGEO_RS11415
uniprot id: Q1IXK4
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

319795:DGEO RS04685
gene id: 319795:DGEO_RS04685
uniprot id: Q1J1C5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane

319795:DGEO RS04830
gene id: 319795:DGEO_RS04830
uniprot id: Q1J199
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

319795:DGEO RS01305
gene id: 319795:DGEO_RS01305
uniprot id: Q1J2V9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

319795:DGEO RS06960
gene id: 319795:DGEO_RS06960
uniprot id: Q1J032
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

319795:DGEO RS13670
gene id: 319795:DGEO_RS13670
uniprot id: Q1IWB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm

319795:DGEO RS10265
gene id: 319795:DGEO_RS10265
uniprot id: Q1IY80
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-3 family.
messages: Cytoplasm
messages: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
messages: Monomer.

319795:DGEO RS13485
gene id: 319795:DGEO_RS13485
uniprot id: Q1IWF3
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

319795:DGEO RS10745
gene id: 319795:DGEO_RS10745
uniprot id: Q1IXY7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

319795:DGEO RS07955
gene id: 319795:DGEO_RS07955
uniprot id: Q1IZI4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane

319795:DGEO RS09930
gene id: 319795:DGEO_RS09930
uniprot id: Q1IYE5
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

319795:DGEO RS05505
gene id: 319795:DGEO_RS05505
uniprot id: Q1J0W6
names: Subcellular Location Annotation
messages: Membrane

319795:DGEO RS01670
gene id: 319795:DGEO_RS01670
uniprot id: Q1J334
names: Subcellular Location Annotation
messages: Membrane

319795:DGEO RS14640
gene id: 319795:DGEO_RS14640
uniprot id: A8ZR51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

319795:DGEO RS05905
gene id: 319795:DGEO_RS05905
uniprot id: Q1J0N8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

319795:DGEO RS08000
gene id: 319795:DGEO_RS08000
uniprot id: Q1IZH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

319795:DGEO RS00845
gene id: 319795:DGEO_RS00845
uniprot id: Q1J2L6
names: Subcellular Location Annotation
messages: Membrane

319795:DGEO RS13780
gene id: 319795:DGEO_RS13780
uniprot id: Q1IW96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

319795:DGEO RS07350
gene id: 319795:DGEO_RS07350
uniprot id: Q1IZV4
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

319795:DGEO RS00400
gene id: 319795:DGEO_RS00400
uniprot id: Q1J3V2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

319795:DGEO RS03775
gene id: 319795:DGEO_RS03775
uniprot id: Q1J1U6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated exonuclease Cas4 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).
messages: Mg(2+) or Mn(2+) required for ssDNA cleavage activity.

319795:DGEO RS06165
gene id: 319795:DGEO_RS06165
uniprot id: Q1J0J1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsbB family. BdbC subfamily.
messages: Membrane

319795:DGEO RS07975
gene id: 319795:DGEO_RS07975
uniprot id: Q1IZH9
names: Similarity
messages: Belongs to the barstar family.

319795:DGEO RS06820
gene id: 319795:DGEO_RS06820
uniprot id: Q1J060
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

319795:DGEO RS05910
gene id: 319795:DGEO_RS05910
uniprot id: Q1J0N7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

319795:DGEO RS05330
gene id: 319795:DGEO_RS05330
uniprot id: Q1J100
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

319795:DGEO RS05185
gene id: 319795:DGEO_RS05185
uniprot id: Q1J129
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

319795:DGEO RS08635
gene id: 319795:DGEO_RS08635
uniprot id: Q1IZ47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

319795:DGEO RS01885
gene id: 319795:DGEO_RS01885
uniprot id: Q1J379
names: Subcellular Location Annotation
messages: Cytoplasm

319795:DGEO RS05760
gene id: 319795:DGEO_RS05760
uniprot id: Q1J0R7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

319795:DGEO RS00270
gene id: 319795:DGEO_RS00270
uniprot id: Q1J3S6
names: Subcellular Location Annotation
messages: Membrane

319795:DGEO RS00450
gene id: 319795:DGEO_RS00450
uniprot id: Q1J3W0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Membrane

319795:DGEO RS14520
gene id: 319795:DGEO_RS14520
uniprot id: Q1IVV4
names: Function
names: Similarity
messages: Belongs to the BCKDHA family.
messages: The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).

319795:DGEO RS10300
gene id: 319795:DGEO_RS10300
uniprot id: Q1IY72
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

319795:DGEO RS13165
gene id: 319795:DGEO_RS13165
uniprot id: Q1IWL8
names: Caution
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

319795:DGEO RS03620
gene id: 319795:DGEO_RS03620
uniprot id: Q1J1X8
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

319795:DGEO RS08705
gene id: 319795:DGEO_RS08705
uniprot id: Q1IZ33
names: Similarity
messages: Belongs to the glutamine synthetase family.

319795:DGEO RS05425
gene id: 319795:DGEO_RS05425
uniprot id: Q1J0Y2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Cell membrane
messages: Membrane

319795:DGEO RS06515
gene id: 319795:DGEO_RS06515
uniprot id: Q1J0C2
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

319795:DGEO RS03310
gene id: 319795:DGEO_RS03310
uniprot id: Q1J238
names: Similarity
messages: Belongs to the cytochrome P450 family.

319795:DGEO RS13955
gene id: 319795:DGEO_RS13955
uniprot id: Q1IW60
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

319795:DGEO RS12745
gene id: 319795:DGEO_RS12745
uniprot id: Q1IWV0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.
messages: Cytoplasm
messages: Homodimer.

319795:DGEO RS08360
gene id: 319795:DGEO_RS08360
uniprot id: Q1IZA2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

319795:DGEO RS06045
gene id: 319795:DGEO_RS06045
uniprot id: Q1J0L4
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

319795:DGEO RS09630
gene id: 319795:DGEO_RS09630
uniprot id: Q1IYK3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm

319795:DGEO RS08605
gene id: 319795:DGEO_RS08605
uniprot id: Q1IZ53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family.
messages: Membrane

319795:DGEO RS01760
gene id: 319795:DGEO_RS01760
uniprot id: Q1J352
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

319795:DGEO RS02680
gene id: 319795:DGEO_RS02680
uniprot id: Q1J2G1
names: Similarity
messages: Belongs to the Nth/MutY family.

319795:DGEO RS10200
gene id: 319795:DGEO_RS10200
uniprot id: Q1IY90
names: Subcellular Location Annotation
messages: Membrane

319795:DGEO RS04635
gene id: 319795:DGEO_RS04635
uniprot id: Q1J1D5
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

319795:DGEO RS08420
gene id: 319795:DGEO_RS08420
uniprot id: Q1IZ90
names: Subcellular Location Annotation
messages: Membrane

319795:DGEO RS15055
gene id: 319795:DGEO_RS15055
uniprot id: A8ZRD6
names: Function
names: Similarity
messages: Belongs to the ApbE family.
messages: Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.

319795:DGEO RS00310
gene id: 319795:DGEO_RS00310
uniprot id: Q1J3T4
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

319795:DGEO RS11635
gene id: 319795:DGEO_RS11635
uniprot id: Q1IXG2
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

319795:DGEO RS10565
gene id: 319795:DGEO_RS10565
uniprot id: Q1IY21
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

319795:DGEO RS11610
gene id: 319795:DGEO_RS11610
uniprot id: Q1IXG7
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

319795:DGEO RS12395
gene id: 319795:DGEO_RS12395
uniprot id: Q1IX16
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).

319795:DGEO RS06205
gene id: 319795:DGEO_RS06205
uniprot id: Q1J0I3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

319795:DGEO RS05180
gene id: 319795:DGEO_RS05180
uniprot id: Q1J130
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

319795:DGEO RS15090
gene id: 319795:DGEO_RS15090
uniprot id: A8ZR47
names: Function
messages: Involved in the transposition of the insertion sequence.

319795:DGEO RS05420
gene id: 319795:DGEO_RS05420
uniprot id: Q1J0Y3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0073 (Hly-III) family.
messages: Membrane

319795:DGEO RS09370
gene id: 319795:DGEO_RS09370
uniprot id: Q1IYQ2
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

319795:DGEO RS11480
gene id: 319795:DGEO_RS11480
uniprot id: Q1IXJ2
names: Similarity
messages: Belongs to the UPF0111 family.

319795:DGEO RS12765
gene id: 319795:DGEO_RS12765
uniprot id: Q1IWU6
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

319795:DGEO RS06580
gene id: 319795:DGEO_RS06580
uniprot id: Q1J0A8
names: Subcellular Location Annotation
messages: Membrane

319795:DGEO RS08295
gene id: 319795:DGEO_RS08295
uniprot id: Q1IZB4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
messages: Cytoplasm
messages: Homodimer.

319795:DGEO RS12055
gene id: 319795:DGEO_RS12055
uniprot id: Q1IX80
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

319795:DGEO RS13390
gene id: 319795:DGEO_RS13390
uniprot id: Q1IWH2
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

319795:DGEO RS12125
gene id: 319795:DGEO_RS12125
uniprot id: Q1IX66
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

319795:DGEO RS00265
gene id: 319795:DGEO_RS00265
uniprot id: Q1J3S5
names: Subcellular Location Annotation
messages: Membrane

319795:DGEO RS12090
gene id: 319795:DGEO_RS12090
uniprot id: Q1IX73
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

319795:DGEO RS07170
gene id: 319795:DGEO_RS07170
uniprot id: Q1IZZ0
names: Subcellular Location Annotation
messages: Membrane

319795:DGEO RS04540
gene id: 319795:DGEO_RS04540
uniprot id: Q1J1F2
names: Similarity
messages: Belongs to the shaker potassium channel beta subunit family.

319795:DGEO RS00655
gene id: 319795:DGEO_RS00655
uniprot id: Q1J3Z5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Membrane

319795:DGEO RS10915
gene id: 319795:DGEO_RS10915
uniprot id: Q1IXV4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

319795:DGEO RS04255
gene id: 319795:DGEO_RS04255
uniprot id: Q1J1K6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

319795:DGEO RS10560
gene id: 319795:DGEO_RS10560
uniprot id: Q1IY22
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

319795:DGEO RS12495
gene id: 319795:DGEO_RS12495
uniprot id: Q1IWZ6
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

319795:DGEO RS09615
gene id: 319795:DGEO_RS09615
uniprot id: Q1IYK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetokinase family.
messages: Cytoplasm

319795:DGEO RS13045
gene id: 319795:DGEO_RS13045
uniprot id: Q1IWP1
names: Function
names: Similarity
messages: Belongs to the V-ATPase V0D/AC39 subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

319795:DGEO RS08855
gene id: 319795:DGEO_RS08855
uniprot id: Q1IZ02
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

319795:DGEO RS09910
gene id: 319795:DGEO_RS09910
uniprot id: Q1IYE9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

319795:DGEO RS03035
gene id: 319795:DGEO_RS03035
uniprot id: Q1J292
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

319795:DGEO RS10820
gene id: 319795:DGEO_RS10820
uniprot id: Q1IXX2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

319795:DGEO RS12565
gene id: 319795:DGEO_RS12565
uniprot id: Q1IWY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

319795:DGEO RS11265
gene id: 319795:DGEO_RS11265
uniprot id: Q1IXN3
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT.

319795:DGEO RS14580
gene id: 319795:DGEO_RS14580
uniprot id: A8ZR40
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

319795:DGEO RS03730
gene id: 319795:DGEO_RS03730
uniprot id: Q1J1V6
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

319795:DGEO RS11390
gene id: 319795:DGEO_RS11390
uniprot id: Q1IXK9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

319795:DGEO RS01585
gene id: 319795:DGEO_RS01585
uniprot id: Q1J317
names: Similarity
messages: Belongs to the glycosyl hydrolase 8 (cellulase D) family.

319795:DGEO RS13690
gene id: 319795:DGEO_RS13690
uniprot id: Q1IWB3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

319795:DGEO RS00095
gene id: 319795:DGEO_RS00095
uniprot id: Q1J3N9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial solute-binding protein 2 family.
messages: Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Binds AI-2 and delivers it to the LsrC and LsrD permeases.
messages: Periplasm
messages: The complex is composed of two ATP-binding proteins (LsrA), two transmembrane proteins (LsrC and LsrD) and a solute-binding protein (LsrB).

319795:DGEO RS05480
gene id: 319795:DGEO_RS05480
uniprot id: Q1J0X1
names: Subcellular Location Annotation
messages: Membrane

319795:DGEO RS06250
gene id: 319795:DGEO_RS06250
uniprot id: Q1J0H4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

319795:DGEO RS02905
gene id: 319795:DGEO_RS02905
uniprot id: Q1J2B7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

319795:DGEO RS05440
gene id: 319795:DGEO_RS05440
uniprot id: Q1J0X9
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSP33 family.
messages: Cytoplasm
messages: Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.
messages: Under oxidizing conditions two disulfide bonds are formed involving the reactive cysteines. Under reducing conditions zinc is bound to the reactive cysteines and the protein is inactive.

319795:DGEO RS11730
gene id: 319795:DGEO_RS11730
uniprot id: Q1IXE2
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

319795:DGEO RS12245
gene id: 319795:DGEO_RS12245
uniprot id: Q1IX43
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TtcA family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is chelated by three Cys residues, the fourth Fe has a free coordination site that may bind a sulfur atom transferred from the persulfide of IscS.
messages: Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
messages: Cytoplasm
messages: Homodimer.
messages: The thiolation reaction likely consists of two steps: a first activation step by ATP to form an adenylated intermediate of the target base of tRNA, and a second nucleophilic substitution step of the sulfur (S) atom supplied by the hydrosulfide attached to the Fe-S cluster.

319795:DGEO RS05035
gene id: 319795:DGEO_RS05035
uniprot id: Q1J158
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

319795:DGEO RS01165
gene id: 319795:DGEO_RS01165
uniprot id: Q1J2T0
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

319795:DGEO RS06465
gene id: 319795:DGEO_RS06465
uniprot id: Q1J0D2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

319795:DGEO RS08910
gene id: 319795:DGEO_RS08910
uniprot id: Q1IYZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
messages: Cell inner membrane
messages: Membrane

319795:DGEO RS03810
gene id: 319795:DGEO_RS03810
uniprot id: Q1J1U0
names: Function
names: Similarity
messages: Belongs to the methylglyoxal synthase family.
messages: Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.

319795:DGEO RS13755
gene id: 319795:DGEO_RS13755
uniprot id: Q1IWA0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

319795:DGEO RS07310
gene id: 319795:DGEO_RS07310
uniprot id: Q1IZW2
names: Subcellular Location Annotation
messages: Membrane

319795:DGEO RS11400
gene id: 319795:DGEO_RS11400
uniprot id: Q1IXK7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm

319795:DGEO RS13190
gene id: 319795:DGEO_RS13190
uniprot id: Q1IWL3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

319795:DGEO RS07445
gene id: 319795:DGEO_RS07445
uniprot id: Q1IZT7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

319795:DGEO RS13565
gene id: 319795:DGEO_RS13565
uniprot id: Q1IWD7
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

319795:DGEO RS12420
gene id: 319795:DGEO_RS12420
uniprot id: Q1IX11
names: Subcellular Location Annotation
messages: Membrane

319795:DGEO RS04800
gene id: 319795:DGEO_RS04800
uniprot id: Q1J1A3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

319795:DGEO RS12990
gene id: 319795:DGEO_RS12990
uniprot id: Q1IWQ2
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Periplasm

319795:DGEO RS03470
gene id: 319795:DGEO_RS03470
uniprot id: Q1J206
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

319795:DGEO RS02040
gene id: 319795:DGEO_RS02040
uniprot id: Q1J3A8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

319795:DGEO RS11195
gene id: 319795:DGEO_RS11195
uniprot id: Q1IXP8
names: Subcellular Location Annotation
messages: Membrane

319795:DGEO RS05545
gene id: 319795:DGEO_RS05545
uniprot id: Q1J0V8
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

319795:DGEO RS12040
gene id: 319795:DGEO_RS12040
uniprot id: Q1IX83
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

319795:DGEO RS13175
gene id: 319795:DGEO_RS13175
uniprot id: Q1IWL6
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

319795:DGEO RS07305
gene id: 319795:DGEO_RS07305
uniprot id: Q1IZW3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: NDH-1 is composed of 15 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

319795:DGEO RS00560
gene id: 319795:DGEO_RS00560
uniprot id: Q1J3X6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

319795:DGEO RS11655
gene id: 319795:DGEO_RS11655
uniprot id: Q1IXF8
names: Subcellular Location Annotation
messages: Membrane

319795:DGEO RS10910
gene id: 319795:DGEO_RS10910
uniprot id: Q1IXV5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

319795:DGEO RS09620
gene id: 319795:DGEO_RS09620
uniprot id: Q1IYK5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

319795:DGEO RS11970
gene id: 319795:DGEO_RS11970
uniprot id: Q1IX97
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

319795:DGEO RS01285
gene id: 319795:DGEO_RS01285
uniprot id: Q1J2V5
names: Similarity
messages: In the C-terminal section; belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

319795:DGEO RS12025
gene id: 319795:DGEO_RS12025
uniprot id: Q1IX86
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

319795:DGEO RS02555
gene id: 319795:DGEO_RS02555
uniprot id: Q1J3L8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

319795:DGEO RS04400
gene id: 319795:DGEO_RS04400
uniprot id: Q1J1H9
names: Similarity
messages: Belongs to the phosphohexose mutase family.

319795:DGEO RS02995
gene id: 319795:DGEO_RS02995
uniprot id: Q1J299
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

319795:DGEO RS06565
gene id: 319795:DGEO_RS06565
uniprot id: Q1J0B1
names: Similarity
messages: Belongs to the AlaDH/PNT family.

319795:DGEO RS04855
gene id: 319795:DGEO_RS04855
uniprot id: Q1J194
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

319795:DGEO RS11015
gene id: 319795:DGEO_RS11015
uniprot id: Q1IXT3
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

319795:DGEO RS03185
gene id: 319795:DGEO_RS03185
uniprot id: Q1J263
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

319795:DGEO RS12300
gene id: 319795:DGEO_RS12300
uniprot id: Q1IX32
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

319795:DGEO RS13925
gene id: 319795:DGEO_RS13925
uniprot id: Q1IW66
names: Similarity
messages: Belongs to the peptidase M16 family.

319795:DGEO RS09740
gene id: 319795:DGEO_RS09740
uniprot id: Q1IYI0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
messages: Cytoplasm

319795:DGEO RS04520
gene id: 319795:DGEO_RS04520
uniprot id: Q1J1F6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
messages: Cytoplasm

319795:DGEO RS12075
gene id: 319795:DGEO_RS12075
uniprot id: Q1IX76
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

319795:DGEO RS08570
gene id: 319795:DGEO_RS08570
uniprot id: Q1IZ60
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

319795:DGEO RS02305
gene id: 319795:DGEO_RS02305
uniprot id: Q1J3G4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

319795:DGEO RS13800
gene id: 319795:DGEO_RS13800
uniprot id: Q1IW91
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

319795:DGEO RS10530
gene id: 319795:DGEO_RS10530
uniprot id: Q1IY28
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

319795:DGEO RS03790
gene id: 319795:DGEO_RS03790
uniprot id: Q1J1U3
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated protein Cas5 family. Subtype I-C/Dvulg subfamily.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).

319795:DGEO RS02970
gene id: 319795:DGEO_RS02970
uniprot id: Q1J2A4
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

319795:DGEO RS07300
gene id: 319795:DGEO_RS07300
uniprot id: Q1IZW4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

319795:DGEO RS00625
gene id: 319795:DGEO_RS00625
uniprot id: Q1J3Y9
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

319795:DGEO RS10860
gene id: 319795:DGEO_RS10860
uniprot id: Q1IXW5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

319795:DGEO RS04840
gene id: 319795:DGEO_RS04840
uniprot id: Q1J197
names: Similarity
messages: Belongs to the fabD family.

319795:DGEO RS13155
gene id: 319795:DGEO_RS13155
uniprot id: Q1IWM0
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

319795:DGEO RS02685
gene id: 319795:DGEO_RS02685
uniprot id: Q1J2G0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

319795:DGEO RS13090
gene id: 319795:DGEO_RS13090
uniprot id: Q1IWN3
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

319795:DGEO RS00555
gene id: 319795:DGEO_RS00555
uniprot id: Q1J3X5
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

319795:DGEO RS03340
gene id: 319795:DGEO_RS03340
uniprot id: Q1J232
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.

319795:DGEO RS12755
gene id: 319795:DGEO_RS12755
uniprot id: Q1IWU8
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT.

319795:DGEO RS08055
gene id: 319795:DGEO_RS08055
uniprot id: Q1IZG3
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

319795:DGEO RS07780
gene id: 319795:DGEO_RS07780
uniprot id: Q1IZM1
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the ferredoxin--NADP reductase type 2 family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

319795:DGEO RS02785
gene id: 319795:DGEO_RS02785
uniprot id: Q1J2E1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

319795:DGEO RS05320
gene id: 319795:DGEO_RS05320
uniprot id: Q1J102
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. TCR/Tet family.
messages: Membrane

319795:DGEO RS03735
gene id: 319795:DGEO_RS03735
uniprot id: Q1J1V5
names: Subcellular Location Annotation
messages: Membrane

319795:DGEO RS15450
gene id: 319795:DGEO_RS15450
uniprot id: A8ZR47
names: Function
messages: Involved in the transposition of the insertion sequence.

319795:DGEO RS03315
gene id: 319795:DGEO_RS03315
uniprot id: Q1J237
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxine kinase family. PdxY subfamily.
messages: Homodimer.
messages: Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP.

319795:DGEO RS07835
gene id: 319795:DGEO_RS07835
uniprot id: Q1IZK9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

319795:DGEO RS13360
gene id: 319795:DGEO_RS13360
uniprot id: Q1IWH9
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Periplasm

319795:DGEO RS03925
gene id: 319795:DGEO_RS03925
uniprot id: Q1J1R8
names: Similarity
messages: Belongs to the GSP E family.

319795:DGEO RS03955
gene id: 319795:DGEO_RS03955
uniprot id: Q1J1R3
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the NOS family. Bacterial NOS oxygenase subfamily.
messages: Catalyzes the production of nitric oxide.
messages: Homodimer.
messages: This protein is similar to the oxygenase domain of eukaryotic nitric oxide synthases but lacks the reductase domain which, in eukaryotes, is responsible for transfer of electrons to the ferric heme during nitric oxide synthesis.

319795:DGEO RS03890
gene id: 319795:DGEO_RS03890
uniprot id: Q1J1S5
names: Similarity
messages: Belongs to the GSP E family.

319795:DGEO RS11925
gene id: 319795:DGEO_RS11925
uniprot id: Q1IXA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

319795:DGEO RS02910
gene id: 319795:DGEO_RS02910
uniprot id: Q1J2B6
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

319795:DGEO RS06065
gene id: 319795:DGEO_RS06065
uniprot id: Q1J0L0
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

319795:DGEO RS01085
gene id: 319795:DGEO_RS01085
uniprot id: Q1J2R4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

319795:DGEO RS06460
gene id: 319795:DGEO_RS06460
uniprot id: Q1J0D3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

319795:DGEO RS01345
gene id: 319795:DGEO_RS01345
uniprot id: Q1J2W7
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

319795:DGEO RS14285
gene id: 319795:DGEO_RS14285
uniprot id: Q1IVZ9
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

319795:DGEO RS10385
gene id: 319795:DGEO_RS10385
uniprot id: Q1IY55
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the kynureninase family.
messages: Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

319795:DGEO RS14495
gene id: 319795:DGEO_RS14495
uniprot id: Q1IVV9
names: Similarity
messages: Belongs to the ParB family.

319795:DGEO RS08900
gene id: 319795:DGEO_RS08900
uniprot id: Q1IYZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmC/CycZ/HelC family.
messages: Membrane

319795:DGEO RS05000
gene id: 319795:DGEO_RS05000
uniprot id: Q1J165
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

319795:DGEO RS08115
gene id: 319795:DGEO_RS08115
uniprot id: Q1IZF1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M3B family.
messages: Binds 1 zinc ion.
messages: Has oligopeptidase activity and degrades a variety of small bioactive peptides.

319795:DGEO RS04130
gene id: 319795:DGEO_RS04130
uniprot id: Q1J1M9
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

319795:DGEO RS13905
gene id: 319795:DGEO_RS13905
uniprot id: Q1IW70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

319795:DGEO RS07125
gene id: 319795:DGEO_RS07125
uniprot id: Q1IZZ9
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family.

319795:DGEO RS12775
gene id: 319795:DGEO_RS12775
uniprot id: Q1IWU4
names: Caution
names: Function
names: Similarity
messages: Belongs to the Dus family. DusA subfamily.
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

319795:DGEO RS03145
gene id: 319795:DGEO_RS03145
uniprot id: Q1J271
names: Similarity
messages: Belongs to the Nudix hydrolase family.

319795:DGEO RS00785
gene id: 319795:DGEO_RS00785
uniprot id: Q1J2K5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpA family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds the extracellular potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

319795:DGEO RS04465
gene id: 319795:DGEO_RS04465
uniprot id: Q1J1G6
names: Similarity
messages: Belongs to the peptidase S9C family.

319795:DGEO RS08675
gene id: 319795:DGEO_RS08675
uniprot id: Q1IZ39
names: Function
names: Similarity
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

319795:DGEO RS08760
gene id: 319795:DGEO_RS08760
uniprot id: Q1IZ22
names: Similarity
messages: Belongs to the ClpA/ClpB family.

319795:DGEO RS05345
gene id: 319795:DGEO_RS05345
uniprot id: Q1J0Z7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

319795:DGEO RS14290
gene id: 319795:DGEO_RS14290
uniprot id: Q1IVZ8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

319795:DGEO RS10125
gene id: 319795:DGEO_RS10125
uniprot id: Q1IYA6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

319795:DGEO RS07060
gene id: 319795:DGEO_RS07060
uniprot id: Q1J012
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

319795:DGEO RS06870
gene id: 319795:DGEO_RS06870
uniprot id: Q1J049
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

319795:DGEO RS15035
gene id: 319795:DGEO_RS15035
uniprot id: A8ZRD2
names: Similarity
messages: Belongs to the alkaline phosphatase family.

319795:DGEO RS01985
gene id: 319795:DGEO_RS01985
uniprot id: Q1J399
names: Function
names: Similarity
messages: Belongs to the uricase family.
messages: Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin.

319795:DGEO RS06585
gene id: 319795:DGEO_RS06585
uniprot id: Q1J0A7
names: Subcellular Location Annotation
messages: Membrane

319795:DGEO RS04380
gene id: 319795:DGEO_RS04380
uniprot id: Q1J1I3
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

319795:DGEO RS03110
gene id: 319795:DGEO_RS03110
uniprot id: Q1J278
names: Similarity
messages: Belongs to the peptidase S1C family.

319795:DGEO RS08525
gene id: 319795:DGEO_RS08525
uniprot id: Q1IZ69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

319795:DGEO RS01980
gene id: 319795:DGEO_RS01980
uniprot id: Q1J398
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.
messages: Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU).
messages: Homotetramer.

319795:DGEO RS08600
gene id: 319795:DGEO_RS08600
uniprot id: Q1IZ54
names: Subcellular Location Annotation
messages: Membrane

319795:DGEO RS03400
gene id: 319795:DGEO_RS03400
uniprot id: Q1J219
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase Y family.
messages: Cell membrane
messages: Endoribonuclease that initiates mRNA decay.

319795:DGEO RS08875
gene id: 319795:DGEO_RS08875
uniprot id: Q1IYZ8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.

319795:DGEO RS09420
gene id: 319795:DGEO_RS09420
uniprot id: Q1IYP2
names: Similarity
messages: Belongs to the GARS family.

319795:DGEO RS10550
gene id: 319795:DGEO_RS10550
uniprot id: Q1IY24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OXA1/ALB3/YidC family.
messages: Membrane

319795:DGEO RS06000
gene id: 319795:DGEO_RS06000
uniprot id: Q1J0M3
names: Subcellular Location Annotation
messages: Membrane

319795:DGEO RS07270
gene id: 319795:DGEO_RS07270
uniprot id: Q1IZX0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 15 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

319795:DGEO RS11515
gene id: 319795:DGEO_RS11515
uniprot id: Q1IXI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

319795:DGEO RS14030
gene id: 319795:DGEO_RS14030
uniprot id: Q1IW48
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

319795:DGEO RS03290
gene id: 319795:DGEO_RS03290
uniprot id: Q1J242
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

319795:DGEO RS00365
gene id: 319795:DGEO_RS00365
uniprot id: Q1J3U5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

319795:DGEO RS11305
gene id: 319795:DGEO_RS11305
uniprot id: Q1IXM5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

319795:DGEO RS08105
gene id: 319795:DGEO_RS08105
uniprot id: Q1IZF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

319795:DGEO RS07985
gene id: 319795:DGEO_RS07985
uniprot id: Q1IZH7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

319795:DGEO RS05790
gene id: 319795:DGEO_RS05790
uniprot id: Q1J0R1
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

319795:DGEO RS11255
gene id: 319795:DGEO_RS11255
uniprot id: Q1IXN5
names: Similarity
messages: Belongs to the transposase 7 family.

319795:DGEO RS04930
gene id: 319795:DGEO_RS04930
uniprot id: Q1J180
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

319795:DGEO RS06345
gene id: 319795:DGEO_RS06345
uniprot id: Q1J0F6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

319795:DGEO RS13070
gene id: 319795:DGEO_RS13070
uniprot id: Q1IWN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

319795:DGEO RS01300
gene id: 319795:DGEO_RS01300
uniprot id: Q1J2V8
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

319795:DGEO RS02790
gene id: 319795:DGEO_RS02790
uniprot id: Q1J2E0
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

319795:DGEO RS01355
gene id: 319795:DGEO_RS01355
uniprot id: Q1J2W9
names: Similarity
messages: Belongs to the arginase family.

319795:DGEO RS10380
gene id: 319795:DGEO_RS10380
uniprot id: Q1IY56
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Cyclase 1 superfamily. KynB family.
messages: Binds 2 zinc ions per subunit.
messages: Catalyzes the hydrolysis of N-formyl-L-kynurenine to L-kynurenine, the second step in the kynurenine pathway of tryptophan degradation.
messages: Homodimer.

319795:DGEO RS03720
gene id: 319795:DGEO_RS03720
uniprot id: Q1J1V8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

319795:DGEO RS12735
gene id: 319795:DGEO_RS12735
uniprot id: Q1IWV2
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

319795:DGEO RS01615
gene id: 319795:DGEO_RS01615
uniprot id: Q1J323
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0394 family.
messages: Membrane

319795:DGEO RS04960
gene id: 319795:DGEO_RS04960
uniprot id: Q1J173
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

319795:DGEO RS08640
gene id: 319795:DGEO_RS08640
uniprot id: Q1IZ46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

319795:DGEO RS03910
gene id: 319795:DGEO_RS03910
uniprot id: Q1J1S1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

319795:DGEO RS07630
gene id: 319795:DGEO_RS07630
uniprot id: Q1IZQ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

319795:DGEO RS14095
gene id: 319795:DGEO_RS14095
uniprot id: Q1IW38
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

319795:DGEO RS08720
gene id: 319795:DGEO_RS08720
uniprot id: Q1IZ30
names: Subcellular Location Annotation
messages: Membrane

319795:DGEO RS10410
gene id: 319795:DGEO_RS10410
uniprot id: Q1IY50
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Monomer.

319795:DGEO RS05775
gene id: 319795:DGEO_RS05775
uniprot id: Q1J0R4
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

319795:DGEO RS08350
gene id: 319795:DGEO_RS08350
uniprot id: Q1IZA4
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

319795:DGEO RS05240
gene id: 319795:DGEO_RS05240
uniprot id: Q1J118
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

319795:DGEO RS06850
gene id: 319795:DGEO_RS06850
uniprot id: Q1J053
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BBS4 family.
messages: Membrane
messages: centrosome
messages: cilium membrane

319795:DGEO RS06055
gene id: 319795:DGEO_RS06055
uniprot id: Q1J0L2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

319795:DGEO RS05030
gene id: 319795:DGEO_RS05030
uniprot id: Q1J159
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

319795:DGEO RS05125
gene id: 319795:DGEO_RS05125
uniprot id: Q1J141
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. Xpt subfamily.
messages: Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.
messages: Cytoplasm
messages: Homodimer.

319795:DGEO RS09850
gene id: 319795:DGEO_RS09850
uniprot id: Q1IYF9
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

319795:DGEO RS06520
gene id: 319795:DGEO_RS06520
uniprot id: Q1J0C1
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

319795:DGEO RS12270
gene id: 319795:DGEO_RS12270
uniprot id: Q1IX38
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the PRA-PH family.
messages: In the N-terminal section; belongs to the PRA-CH family.

319795:DGEO RS14170
gene id: 319795:DGEO_RS14170
uniprot id: Q1IW22
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DtxR/MntR family.
messages: Cytoplasm
messages: Homodimer.

319795:DGEO RS03865
gene id: 319795:DGEO_RS03865
uniprot id: Q1J1T0
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

319795:DGEO RS00025
gene id: 319795:DGEO_RS00025
uniprot id: Q1J3M8
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily.

319795:DGEO RS01560
gene id: 319795:DGEO_RS01560
uniprot id: Q1J309
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the xylose isomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.

319795:DGEO RS01765
gene id: 319795:DGEO_RS01765
uniprot id: Q1J353
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. Fucose synthase subfamily.

319795:DGEO RS14405
gene id: 319795:DGEO_RS14405
uniprot id: Q1IVX6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

319795:DGEO RS09680
gene id: 319795:DGEO_RS09680
uniprot id: Q1IYJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

319795:DGEO RS12135
gene id: 319795:DGEO_RS12135
uniprot id: Q1IX64
names: Similarity
messages: Belongs to the phosphohexose mutase family.

319795:DGEO RS14160
gene id: 319795:DGEO_RS14160
uniprot id: Q1IW24
names: Similarity
messages: Belongs to the TrpF family.

319795:DGEO RS12605
gene id: 319795:DGEO_RS12605
uniprot id: Q1IWX4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

319795:DGEO RS00735
gene id: 319795:DGEO_RS00735
uniprot id: Q1J2J5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

319795:DGEO RS03405
gene id: 319795:DGEO_RS03405
uniprot id: Q1J218
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

319795:DGEO RS11985
gene id: 319795:DGEO_RS11985
uniprot id: Q1IX94
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

319795:DGEO RS13130
gene id: 319795:DGEO_RS13130
uniprot id: Q1IWM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

319795:DGEO RS05900
gene id: 319795:DGEO_RS05900
uniprot id: Q1J0N9
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

319795:DGEO RS01490
gene id: 319795:DGEO_RS01490
uniprot id: Q1J2Z6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Membrane

319795:DGEO RS05055
gene id: 319795:DGEO_RS05055
uniprot id: Q1J154
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.

319795:DGEO RS01610
gene id: 319795:DGEO_RS01610
uniprot id: Q1J322
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

319795:DGEO RS12560
gene id: 319795:DGEO_RS12560
uniprot id: Q1IWY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

319795:DGEO RS10140
gene id: 319795:DGEO_RS10140
uniprot id: Q1IYA3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

319795:DGEO RS13295
gene id: 319795:DGEO_RS13295
uniprot id: Q1IWJ1
names: Function
names: Similarity
messages: Belongs to the MqnA/MqnD family. MqnA subfamily.
messages: Catalyzes the dehydration of chorismate into 3-[(1-carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).

319795:DGEO RS01395
gene id: 319795:DGEO_RS01395
uniprot id: Q1J2X7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

319795:DGEO RS08320
gene id: 319795:DGEO_RS08320
uniprot id: Q1IZB0
names: Similarity
messages: Belongs to the aspartokinase family.

319795:DGEO RS07905
gene id: 319795:DGEO_RS07905
uniprot id: Q1IZJ5
names: Similarity
messages: Belongs to the prephenate/arogenate dehydrogenase family.

319795:DGEO RS07730
gene id: 319795:DGEO_RS07730
uniprot id: Q1IZN1
names: Similarity
messages: Belongs to the flavin oxidoreductase frp family.

319795:DGEO RS04660
gene id: 319795:DGEO_RS04660
uniprot id: Q1J1D0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

319795:DGEO RS13840
gene id: 319795:DGEO_RS13840
uniprot id: Q1IW83
names: Similarity
messages: Belongs to the SufE family.

319795:DGEO RS06855
gene id: 319795:DGEO_RS06855
uniprot id: Q1J052
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

319795:DGEO RS07660
gene id: 319795:DGEO_RS07660
uniprot id: Q1IZP5
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

319795:DGEO RS06035
gene id: 319795:DGEO_RS06035
uniprot id: Q1J0L6
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

319795:DGEO RS09655
gene id: 319795:DGEO_RS09655
uniprot id: Q1IYJ8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M20A family. LysK subfamily.
messages: Binds 2 Zn(2+) or Co(2+) ions per subunit.
messages: Catalyzes the release of L-lysine from [LysW]-gamma-L-lysine.
messages: Cytoplasm

319795:DGEO RS10725
gene id: 319795:DGEO_RS10725
uniprot id: Q1IXZ0
names: Similarity
messages: Belongs to the RecJ family.

319795:DGEO RS05045
gene id: 319795:DGEO_RS05045
uniprot id: Q1J156
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

319795:DGEO RS00595
gene id: 319795:DGEO_RS00595
uniprot id: Q1J3Y3
names: Similarity
messages: Belongs to the CobH/CbiC family.

319795:DGEO RS11685
gene id: 319795:DGEO_RS11685
uniprot id: Q1IXF1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Probably interacts with PlsX.

319795:DGEO RS06720
gene id: 319795:DGEO_RS06720
uniprot id: Q1J080
names: Subcellular Location Annotation
messages: Membrane

319795:DGEO RS03500
gene id: 319795:DGEO_RS03500
uniprot id: Q1J200
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

319795:DGEO RS10875
gene id: 319795:DGEO_RS10875
uniprot id: Q1IXW2
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

319795:DGEO RS07225
gene id: 319795:DGEO_RS07225
uniprot id: Q1IZX9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

319795:DGEO RS10330
gene id: 319795:DGEO_RS10330
uniprot id: Q1IY66
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

319795:DGEO RS11780
gene id: 319795:DGEO_RS11780
uniprot id: Q1IXD5
names: Similarity
messages: Belongs to the dGTPase family. Type 2 subfamily.

319795:DGEO RS13615
gene id: 319795:DGEO_RS13615
uniprot id: Q1IWC8
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

319795:DGEO RS02220
gene id: 319795:DGEO_RS02220
uniprot id: Q1J3E7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

319795:DGEO RS05585
gene id: 319795:DGEO_RS05585
uniprot id: Q1J0V0
names: Similarity
messages: Belongs to the SCO1/2 family.

319795:DGEO RS10605
gene id: 319795:DGEO_RS10605
uniprot id: Q1IY13
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

319795:DGEO RS00840
gene id: 319795:DGEO_RS00840
uniprot id: Q1J2L5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

319795:DGEO RS06690
gene id: 319795:DGEO_RS06690
uniprot id: Q1J086
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 2 subfamily.
messages: Cytoplasm
messages: Homodimer.

319795:DGEO RS01260
gene id: 319795:DGEO_RS01260
uniprot id: Q1J2V0
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

319795:DGEO RS11965
gene id: 319795:DGEO_RS11965
uniprot id: Q1IX98
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

319795:DGEO RS05885
gene id: 319795:DGEO_RS05885
uniprot id: Q1J0P2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

319795:DGEO RS15065
gene id: 319795:DGEO_RS15065
uniprot id: A8ZRD8
names: Subcellular Location Annotation
messages: Membrane

319795:DGEO RS12065
gene id: 319795:DGEO_RS12065
uniprot id: Q1IX78
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

319795:DGEO RS12600
gene id: 319795:DGEO_RS12600
uniprot id: Q1IWX5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Forms a complex with TatA.
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.

319795:DGEO RS15530
gene id: 319795:DGEO_RS15530
uniprot id: A8ZRN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

319795:DGEO RS06980
gene id: 319795:DGEO_RS06980
uniprot id: Q1J027
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

319795:DGEO RS13215
gene id: 319795:DGEO_RS13215
uniprot id: Q1IWK7
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

319795:DGEO RS01390
gene id: 319795:DGEO_RS01390
uniprot id: Q1J2X6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

319795:DGEO RS01470
gene id: 319795:DGEO_RS01470
uniprot id: Q1J2Z2
names: Subcellular Location Annotation
messages: Membrane

319795:DGEO RS02365
gene id: 319795:DGEO_RS02365
uniprot id: Q1J3H9
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

319795:DGEO RS02415
gene id: 319795:DGEO_RS02415
uniprot id: Q1J3I9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

319795:DGEO RS06185
gene id: 319795:DGEO_RS06185
uniprot id: Q1J0I7
names: Similarity
messages: Belongs to the BMP lipoprotein family.

319795:DGEO RS10215
gene id: 319795:DGEO_RS10215
uniprot id: Q1IY87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

319795:DGEO RS12215
gene id: 319795:DGEO_RS12215
uniprot id: Q1IX49
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

319795:DGEO RS05195
gene id: 319795:DGEO_RS05195
uniprot id: Q1J127
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

319795:DGEO RS07870
gene id: 319795:DGEO_RS07870
uniprot id: Q1IZK2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

319795:DGEO RS07290
gene id: 319795:DGEO_RS07290
uniprot id: Q1IZW6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: NDH-1 is composed of 15 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

319795:DGEO RS12115
gene id: 319795:DGEO_RS12115
uniprot id: Q1IX68
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

319795:DGEO RS09865
gene id: 319795:DGEO_RS09865
uniprot id: Q1IYF6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

319795:DGEO RS13060
gene id: 319795:DGEO_RS13060
uniprot id: Q1IWN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Membrane

319795:DGEO RS13585
gene id: 319795:DGEO_RS13585
uniprot id: Q1IWD3
names: Subcellular Location Annotation
messages: Membrane

319795:DGEO RS03635
gene id: 319795:DGEO_RS03635
uniprot id: Q1J1X5
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

319795:DGEO RS08200
gene id: 319795:DGEO_RS08200
uniprot id: Q1IZD3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

319795:DGEO RS10890
gene id: 319795:DGEO_RS10890
uniprot id: Q1IXV9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).

319795:DGEO RS13890
gene id: 319795:DGEO_RS13890
uniprot id: Q1IW73
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

319795:DGEO RS07155
gene id: 319795:DGEO_RS07155
uniprot id: Q1IZZ3
names: Cofactor
messages: The heme is bound between the two transmembrane subunits.

319795:DGEO RS16830
gene id: 319795:DGEO_RS16830
uniprot id: A8ZRD7
names: Subcellular Location Annotation
messages: Membrane

319795:DGEO RS05265
gene id: 319795:DGEO_RS05265
uniprot id: Q1J113
names: Similarity
messages: Belongs to the Fur family.

319795:DGEO RS09530
gene id: 319795:DGEO_RS09530
uniprot id: Q1IYM0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

319795:DGEO RS05540
gene id: 319795:DGEO_RS05540
uniprot id: Q1J0V9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

319795:DGEO RS08440
gene id: 319795:DGEO_RS08440
uniprot id: Q1IZ86
names: Similarity
messages: Belongs to the RimK family. LysX subfamily.

319795:DGEO RS09345
gene id: 319795:DGEO_RS09345
uniprot id: Q1IYQ6
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

319795:DGEO RS09395
gene id: 319795:DGEO_RS09395
uniprot id: Q1IYP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

319795:DGEO RS11555
gene id: 319795:DGEO_RS11555
uniprot id: Q1IXH7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

319795:DGEO RS05560
gene id: 319795:DGEO_RS05560
uniprot id: Q1J0V5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

319795:DGEO RS08135
gene id: 319795:DGEO_RS08135
uniprot id: Q1IZE7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

319795:DGEO RS01400
gene id: 319795:DGEO_RS01400
uniprot id: Q1J2X8
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

319795:DGEO RS12800
gene id: 319795:DGEO_RS12800
uniprot id: Q1IWT9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

319795:DGEO RS05820
gene id: 319795:DGEO_RS05820
uniprot id: Q1J0Q5
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

319795:DGEO RS09150
gene id: 319795:DGEO_RS09150
uniprot id: Q1IYU4
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

319795:DGEO RS05255
gene id: 319795:DGEO_RS05255
uniprot id: Q1J115
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

319795:DGEO RS03930
gene id: 319795:DGEO_RS03930
uniprot id: Q1J1R7
names: Similarity
messages: Belongs to the GSP E family.

319795:DGEO RS00575
gene id: 319795:DGEO_RS00575
uniprot id: Q1J3X9
names: Similarity
messages: Belongs to the alkaline phosphatase family.

319795:DGEO RS15115
gene id: 319795:DGEO_RS15115
uniprot id: A8ZR47
names: Function
messages: Involved in the transposition of the insertion sequence.

319795:DGEO RS05815
gene id: 319795:DGEO_RS05815
uniprot id: Q1J0Q6
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

319795:DGEO RS06805
gene id: 319795:DGEO_RS06805
uniprot id: Q1J063
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

319795:DGEO RS05675
gene id: 319795:DGEO_RS05675
uniprot id: Q1J0T3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homotetramer.

319795:DGEO RS05005
gene id: 319795:DGEO_RS05005
uniprot id: Q1J164
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

319795:DGEO RS13965
gene id: 319795:DGEO_RS13965
uniprot id: Q1IW58
names: Function
names: Similarity
messages: Belongs to the BPG-independent phosphoglycerate mutase family. A-PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

319795:DGEO RS02265
gene id: 319795:DGEO_RS02265
uniprot id: Q1J3F6
names: Similarity
messages: Belongs to the UPF0166 family.

319795:DGEO RS08240
gene id: 319795:DGEO_RS08240
uniprot id: Q1IZC5
names: Similarity
messages: Belongs to the peptidase C40 family.

319795:DGEO RS00665
gene id: 319795:DGEO_RS00665
uniprot id: Q1J2I1
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.

319795:DGEO RS03450
gene id: 319795:DGEO_RS03450
uniprot id: Q1J210
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

319795:DGEO RS13405
gene id: 319795:DGEO_RS13405
uniprot id: Q1IWG9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

319795:DGEO RS13935
gene id: 319795:DGEO_RS13935
uniprot id: Q1IW64
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

319795:DGEO RS06405
gene id: 319795:DGEO_RS06405
uniprot id: Q1J0E4
names: Subcellular Location Annotation
messages: Membrane

319795:DGEO RS06830
gene id: 319795:DGEO_RS06830
uniprot id: Q1J058
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

319795:DGEO RS06335
gene id: 319795:DGEO_RS06335
uniprot id: Q1J0F8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

319795:DGEO RS07315
gene id: 319795:DGEO_RS07315
uniprot id: Q1IZW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

319795:DGEO RS01675
gene id: 319795:DGEO_RS01675
uniprot id: Q1J335
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

319795:DGEO RS07795
gene id: 319795:DGEO_RS07795
uniprot id: Q1IZL8
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

319795:DGEO RS08400
gene id: 319795:DGEO_RS08400
uniprot id: Q1IZ94
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

319795:DGEO RS03270
gene id: 319795:DGEO_RS03270
uniprot id: Q1J246
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the adenylate cyclase family. DacA/CdaA subfamily.
messages: Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably a homodimer.

319795:DGEO RS09055
gene id: 319795:DGEO_RS09055
uniprot id: Q1IYW2
names: Similarity
messages: Belongs to the BshC family.

319795:DGEO RS09045
gene id: 319795:DGEO_RS09045
uniprot id: Q1IYW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Membrane

319795:DGEO RS03570
gene id: 319795:DGEO_RS03570
uniprot id: Q1J1Y8
names: Similarity
messages: Belongs to the peptidase S33 family.

319795:DGEO RS11145
gene id: 319795:DGEO_RS11145
uniprot id: Q1IXQ8
names: Similarity
messages: Belongs to the peptidase S8 family.

319795:DGEO RS04925
gene id: 319795:DGEO_RS04925
uniprot id: Q1J181
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

319795:DGEO RS04885
gene id: 319795:DGEO_RS04885
uniprot id: Q1J188
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
messages: Homodimer.

319795:DGEO RS08955
gene id: 319795:DGEO_RS08955
uniprot id: Q1IYY1
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. Homocitrate synthase LYS20/LYS21 subfamily.

319795:DGEO RS06330
gene id: 319795:DGEO_RS06330
uniprot id: Q1J0F9
names: Function
names: Similarity
messages: Belongs to the RapZ-like family.
messages: Displays ATPase and GTPase activities.

319795:DGEO RS12960
gene id: 319795:DGEO_RS12960
uniprot id: Q1IWQ8
names: Subcellular Location Annotation
messages: Membrane

319795:DGEO RS06900
gene id: 319795:DGEO_RS06900
uniprot id: Q1J043
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

319795:DGEO RS08840
gene id: 319795:DGEO_RS08840
uniprot id: Q1IZ06
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

319795:DGEO RS08255
gene id: 319795:DGEO_RS08255
uniprot id: Q1IZC2
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

319795:DGEO RS01860
gene id: 319795:DGEO_RS01860
uniprot id: Q1J374
names: Similarity
messages: Belongs to the glutamate synthase family.

319795:DGEO RS12645
gene id: 319795:DGEO_RS12645
uniprot id: Q1IWW6
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

319795:DGEO RS13420
gene id: 319795:DGEO_RS13420
uniprot id: Q1IWG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

319795:DGEO RS03710
gene id: 319795:DGEO_RS03710
uniprot id: Q1J1W0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.

319795:DGEO RS07245
gene id: 319795:DGEO_RS07245
uniprot id: Q1IZX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

319795:DGEO RS12875
gene id: 319795:DGEO_RS12875
uniprot id: Q1IWS4
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

319795:DGEO RS09975
gene id: 319795:DGEO_RS09975
uniprot id: Q1IYD6
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.

319795:DGEO RS11070
gene id: 319795:DGEO_RS11070
uniprot id: Q1IXS3
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.

319795:DGEO RS00650
gene id: 319795:DGEO_RS00650
uniprot id: Q1J3Z4
names: Domain
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the CobB/CbiA family.
messages: Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source.
messages: Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP and cobyrinate and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.
messages: The a and c carboxylates of cobyrinate are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CbiA catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate.

319795:DGEO RS12935
gene id: 319795:DGEO_RS12935
uniprot id: Q1IWR3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidylate synthase ThyX family.
messages: Binds 4 FAD per tetramer. Each FAD binding site is formed by three monomers.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
messages: Homotetramer.

319795:DGEO RS06150
gene id: 319795:DGEO_RS06150
uniprot id: Q1J0J4
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

319795:DGEO RS02495
gene id: 319795:DGEO_RS02495
uniprot id: Q1J3K6
names: Similarity
messages: Belongs to the ParB family.

319795:DGEO RS03195
gene id: 319795:DGEO_RS03195
uniprot id: Q1J261
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

319795:DGEO RS08290
gene id: 319795:DGEO_RS08290
uniprot id: Q1IZB5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

319795:DGEO RS12965
gene id: 319795:DGEO_RS12965
uniprot id: Q1IWQ7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

319795:DGEO RS11430
gene id: 319795:DGEO_RS11430
uniprot id: Q1IXK1
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

319795:DGEO RS11945
gene id: 319795:DGEO_RS11945
uniprot id: Q1IXA2
names: Similarity
messages: Belongs to the thioredoxin family.

319795:DGEO RS12000
gene id: 319795:DGEO_RS12000
uniprot id: Q1IX91
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

319795:DGEO RS02955
gene id: 319795:DGEO_RS02955
uniprot id: Q1J2A7
names: Similarity
messages: Belongs to the IMPACT family.

319795:DGEO RS03090
gene id: 319795:DGEO_RS03090
uniprot id: Q1J282
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

319795:DGEO RS04880
gene id: 319795:DGEO_RS04880
uniprot id: Q1J189
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

319795:DGEO RS06880
gene id: 319795:DGEO_RS06880
uniprot id: Q1J047
names: Subcellular Location Annotation
messages: Cytoplasm

319795:DGEO RS06280
gene id: 319795:DGEO_RS06280
uniprot id: Q1J0G9
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

319795:DGEO RS13680
gene id: 319795:DGEO_RS13680
uniprot id: Q1IWB5
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

319795:DGEO RS04265
gene id: 319795:DGEO_RS04265
uniprot id: Q1J1K4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RuvC family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.

319795:DGEO RS07215
gene id: 319795:DGEO_RS07215
uniprot id: Q1IZY1
names: Subcellular Location Annotation
messages: Membrane

319795:DGEO RS09105
gene id: 319795:DGEO_RS09105
uniprot id: Q1IYV3
names: Subcellular Location Annotation
messages: Membrane

319795:DGEO RS12165
gene id: 319795:DGEO_RS12165
uniprot id: Q1IX59
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Catalyzes the deamination of dCTP to dUTP.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

319795:DGEO RS02850
gene id: 319795:DGEO_RS02850
uniprot id: Q1J2C8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

319795:DGEO RS12120
gene id: 319795:DGEO_RS12120
uniprot id: Q1IX67
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

319795:DGEO RS12535
gene id: 319795:DGEO_RS12535
uniprot id: Q1IWY8
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.

319795:DGEO RS13140
gene id: 319795:DGEO_RS13140
uniprot id: Q1IWM3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.

319795:DGEO RS10150
gene id: 319795:DGEO_RS10150
uniprot id: Q1IYA1
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

319795:DGEO RS07670
gene id: 319795:DGEO_RS07670
uniprot id: Q1IZP3
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Cytoplasm
messages: Homodimer.
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

319795:DGEO RS15245
gene id: 319795:DGEO_RS15245
uniprot id: A8ZRH5
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

319795:DGEO RS07275
gene id: 319795:DGEO_RS07275
uniprot id: Q1IZW9
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

319795:DGEO RS06200
gene id: 319795:DGEO_RS06200
uniprot id: Q1J0I4
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

319795:DGEO RS07380
gene id: 319795:DGEO_RS07380
uniprot id: Q1IZV0
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

319795:DGEO RS13025
gene id: 319795:DGEO_RS13025
uniprot id: Q1IWP5
names: Function
names: Similarity
messages: Belongs to the V-ATPase D subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

319795:DGEO RS02965
gene id: 319795:DGEO_RS02965
uniprot id: Q1J2A5
names: Similarity
messages: Belongs to the DinB family.

319795:DGEO RS06490
gene id: 319795:DGEO_RS06490
uniprot id: Q1J0C7
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

319795:DGEO RS05015
gene id: 319795:DGEO_RS05015
uniprot id: Q1J162
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

319795:DGEO RS06385
gene id: 319795:DGEO_RS06385
uniprot id: Q1J0E8
names: Subcellular Location Annotation
messages: Membrane

319795:DGEO RS00460
gene id: 319795:DGEO_RS00460
uniprot id: Q1J3Z6
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

319795:DGEO RS14145
gene id: 319795:DGEO_RS14145
uniprot id: Q1IW27
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

319795:DGEO RS13160
gene id: 319795:DGEO_RS13160
uniprot id: Q1IWL9
names: Subcellular Location Annotation
messages: Membrane

319795:DGEO RS03150
gene id: 319795:DGEO_RS03150
uniprot id: Q1J270
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

319795:DGEO RS14645
gene id: 319795:DGEO_RS14645
uniprot id: A8ZR52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

319795:DGEO RS11805
gene id: 319795:DGEO_RS11805
uniprot id: Q1IXD0
names: Similarity
messages: Belongs to the ribF family.

319795:DGEO RS05590
gene id: 319795:DGEO_RS05590
uniprot id: Q1J0U9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

319795:DGEO RS05625
gene id: 319795:DGEO_RS05625
uniprot id: Q1J0U2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

319795:DGEO RS10085
gene id: 319795:DGEO_RS10085
uniprot id: Q1IYB4
names: Similarity
messages: Belongs to the ClpA/ClpB family.

319795:DGEO RS12315
gene id: 319795:DGEO_RS12315
uniprot id: Q1IX29
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

319795:DGEO RS06635
gene id: 319795:DGEO_RS06635
uniprot id: Q1J097
names: Similarity
messages: Belongs to the Nth/MutY family.

319795:DGEO RS13180
gene id: 319795:DGEO_RS13180
uniprot id: Q1IWL5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

319795:DGEO RS11035
gene id: 319795:DGEO_RS11035
uniprot id: Q1IXS9
names: Similarity
messages: Belongs to the DNA glycosylase MPG family.

319795:DGEO RS05355
gene id: 319795:DGEO_RS05355
uniprot id: Q1J0Z5
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family. TreS subfamily.

319795:DGEO RS14395
gene id: 319795:DGEO_RS14395
uniprot id: Q1IVX8
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

319795:DGEO RS01590
gene id: 319795:DGEO_RS01590
uniprot id: Q1J318
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

319795:DGEO RS11995
gene id: 319795:DGEO_RS11995
uniprot id: Q1IX92
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

319795:DGEO RS07920
gene id: 319795:DGEO_RS07920
uniprot id: Q1IZJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

319795:DGEO RS03770
gene id: 319795:DGEO_RS03770
uniprot id: Q1J1U7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

319795:DGEO RS09920
gene id: 319795:DGEO_RS09920
uniprot id: Q1IYE7
names: Similarity
messages: Belongs to the YciI family.

319795:DGEO RS04640
gene id: 319795:DGEO_RS04640
uniprot id: Q1J1D4
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

319795:DGEO RS13095
gene id: 319795:DGEO_RS13095
uniprot id: Q1IWN2
names: Similarity
messages: Belongs to the type IB topoisomerase family.

319795:DGEO RS06395
gene id: 319795:DGEO_RS06395
uniprot id: Q1J0E6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

319795:DGEO RS08995
gene id: 319795:DGEO_RS08995
uniprot id: Q1IYX3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
messages: Homodimer.

319795:DGEO RS12980
gene id: 319795:DGEO_RS12980
uniprot id: Q1IWQ4
names: Similarity
messages: Belongs to the Nudix hydrolase family.

319795:DGEO RS14100
gene id: 319795:DGEO_RS14100
uniprot id: Q1IW37
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

319795:DGEO RS00100
gene id: 319795:DGEO_RS00100
uniprot id: Q1J3P0
names: Subcellular Location Annotation
messages: Membrane

319795:DGEO RS02765
gene id: 319795:DGEO_RS02765
uniprot id: Q1J2E5
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily.

319795:DGEO RS00605
gene id: 319795:DGEO_RS00605
uniprot id: Q1J3Y5
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

319795:DGEO RS02655
gene id: 319795:DGEO_RS02655
uniprot id: Q1J2G6
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

319795:DGEO RS03050
gene id: 319795:DGEO_RS03050
uniprot id: Q1J289
names: Subcellular Location Annotation
messages: Membrane

319795:DGEO RS14620
gene id: 319795:DGEO_RS14620
uniprot id: A8ZR47
names: Function
messages: Involved in the transposition of the insertion sequence.

319795:DGEO RS04700
gene id: 319795:DGEO_RS04700
uniprot id: Q1J1C2
names: Subcellular Location Annotation
messages: Membrane

319795:DGEO RS11215
gene id: 319795:DGEO_RS11215
uniprot id: Q1IXP4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

319795:DGEO RS10360
gene id: 319795:DGEO_RS10360
uniprot id: Q1IY60
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

319795:DGEO RS14505
gene id: 319795:DGEO_RS14505
uniprot id: Q1IVV7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

319795:DGEO RS09735
gene id: 319795:DGEO_RS09735
uniprot id: Q1IYI1
names: Function
names: Similarity
messages: Belongs to the APS kinase family.
messages: Catalyzes the synthesis of activated sulfate.

319795:DGEO RS12350
gene id: 319795:DGEO_RS12350
uniprot id: Q1IX25
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

319795:DGEO RS13075
gene id: 319795:DGEO_RS13075
uniprot id: Q1IWN5
names: Similarity
messages: Belongs to the P(II) protein family.

319795:DGEO RS07655
gene id: 319795:DGEO_RS07655
uniprot id: Q1IZP6
names: Similarity
messages: Belongs to the radical SAM superfamily. KamA family.

319795:DGEO RS03415
gene id: 319795:DGEO_RS03415
uniprot id: Q1J216
names: Caution
names: Function
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

319795:DGEO RS08365
gene id: 319795:DGEO_RS08365
uniprot id: Q1IZA1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

319795:DGEO RS11540
gene id: 319795:DGEO_RS11540
uniprot id: Q1IXI0
names: Caution
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

319795:DGEO RS12070
gene id: 319795:DGEO_RS12070
uniprot id: Q1IX77
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity).

319795:DGEO RS13375
gene id: 319795:DGEO_RS13375
uniprot id: Q1IWH5
names: Subcellular Location Annotation
messages: Membrane

319795:DGEO RS11980
gene id: 319795:DGEO_RS11980
uniprot id: Q1IX95
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

319795:DGEO RS03870
gene id: 319795:DGEO_RS03870
uniprot id: Q1J1S9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

319795:DGEO RS12400
gene id: 319795:DGEO_RS12400
uniprot id: Q1IX15
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

319795:DGEO RS08310
gene id: 319795:DGEO_RS08310
uniprot id: Q1IZB2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

319795:DGEO RS00690
gene id: 319795:DGEO_RS00690
uniprot id: Q1J2I6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

319795:DGEO RS04295
gene id: 319795:DGEO_RS04295
uniprot id: Q1J1K1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

319795:DGEO RS14085
gene id: 319795:DGEO_RS14085
uniprot id: Q1IW40
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

319795:DGEO RS12610
gene id: 319795:DGEO_RS12610
uniprot id: Q1IWX3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.

319795:DGEO RS05890
gene id: 319795:DGEO_RS05890
uniprot id: Q1J0P1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

319795:DGEO RS01685
gene id: 319795:DGEO_RS01685
uniprot id: Q1J337
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: The complex is composed of two ATP-binding proteins (UgpC), two transmembrane proteins (UgpA and UgpE) and a solute-binding protein (UgpB).

319795:DGEO RS10595
gene id: 319795:DGEO_RS10595
uniprot id: Q1IY15
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

319795:DGEO RS07045
gene id: 319795:DGEO_RS07045
uniprot id: Q1J015
names: Subcellular Location Annotation
messages: Membrane

319795:DGEO RS07255
gene id: 319795:DGEO_RS07255
uniprot id: Q1IZX3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

319795:DGEO RS10255
gene id: 319795:DGEO_RS10255
uniprot id: Q1IY82
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged L-seryl-tRNA(Thr).
messages: Cytoplasm
messages: Homodimer.

319795:DGEO RS12985
gene id: 319795:DGEO_RS12985
uniprot id: Q1IWQ3
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

319795:DGEO RS12825
gene id: 319795:DGEO_RS12825
uniprot id: Q1IWT4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

319795:DGEO RS07745
gene id: 319795:DGEO_RS07745
uniprot id: Q1IZM8
names: Subcellular Location Annotation
messages: Cytoplasm

319795:DGEO RS10195
gene id: 319795:DGEO_RS10195
uniprot id: Q1IY91
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

319795:DGEO RS07855
gene id: 319795:DGEO_RS07855
uniprot id: Q1IZK5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

319795:DGEO RS04020
gene id: 319795:DGEO_RS04020
uniprot id: Q1J1Q0
names: Similarity
messages: Belongs to the Dps family.

319795:DGEO RS05865
gene id: 319795:DGEO_RS05865
uniprot id: Q1J0P6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

319795:DGEO RS10490
gene id: 319795:DGEO_RS10490
uniprot id: Q1IY35
names: Similarity
messages: Belongs to the peptidase C40 family.

319795:DGEO RS05290
gene id: 319795:DGEO_RS05290
uniprot id: Q1J108
names: Similarity
messages: Belongs to the carotenoid/retinoid oxidoreductase family.

319795:DGEO RS14555
gene id: 319795:DGEO_RS14555
uniprot id: Q1IVU7
names: Similarity
messages: Belongs to the DprA/Smf family.

319795:DGEO RS10210
gene id: 319795:DGEO_RS10210
uniprot id: Q1IY88
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. MalFG subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Probably responsible for the translocation of the substrate across the membrane.

319795:DGEO RS11120
gene id: 319795:DGEO_RS11120
uniprot id: Q1IXR3
names: Subcellular Location Annotation
messages: Membrane

319795:DGEO RS07435
gene id: 319795:DGEO_RS07435
uniprot id: Q1IZT9
names: Similarity
messages: Belongs to the cytochrome P450 family.

319795:DGEO RS13885
gene id: 319795:DGEO_RS13885
uniprot id: Q1IW74
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

319795:DGEO RS07295
gene id: 319795:DGEO_RS07295
uniprot id: Q1IZW5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: NDH-1 is composed of 15 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

319795:DGEO RS04135
gene id: 319795:DGEO_RS04135
uniprot id: Q1J1M8
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

319795:DGEO RS07645
gene id: 319795:DGEO_RS07645
uniprot id: Q1IZP8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.

319795:DGEO RS12485
gene id: 319795:DGEO_RS12485
uniprot id: Q1IWZ8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

319795:DGEO RS02825
gene id: 319795:DGEO_RS02825
uniprot id: Q1J2D3
names: Subcellular Location Annotation
messages: Membrane

319795:DGEO RS08665
gene id: 319795:DGEO_RS08665
uniprot id: Q1IZ41
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Cytoplasm
messages: Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.

319795:DGEO RS01375
gene id: 319795:DGEO_RS01375
uniprot id: Q1J2X3
names: Similarity
messages: Belongs to the catalase family.

319795:DGEO RS10925
gene id: 319795:DGEO_RS10925
uniprot id: Q1IXV2
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

319795:DGEO RS05740
gene id: 319795:DGEO_RS05740
uniprot id: Q1J0S0
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

319795:DGEO RS04525
gene id: 319795:DGEO_RS04525
uniprot id: Q1J1F5
names: Function
names: Similarity
messages: ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.
messages: Belongs to the ParA family. MinD subfamily.

319795:DGEO RS12430
gene id: 319795:DGEO_RS12430
uniprot id: Q1IX09
names: Similarity
messages: Belongs to the Nudix hydrolase family.

319795:DGEO RS04425
gene id: 319795:DGEO_RS04425
uniprot id: Q1J1H4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pseudouridine-5'-phosphate glycosidase family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the reversible cleavage of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway.
messages: Homotrimer.

319795:DGEO RS02720
gene id: 319795:DGEO_RS02720
uniprot id: Q1J2F3
names: Similarity
messages: Belongs to the XseB family.

319795:DGEO RS04410
gene id: 319795:DGEO_RS04410
uniprot id: Q1J1H7
names: Subcellular Location Annotation
messages: Cytoplasm

319795:DGEO RS12235
gene id: 319795:DGEO_RS12235
uniprot id: Q1IX45
names: Similarity
messages: Belongs to the UPF0102 family.

319795:DGEO RS00955
gene id: 319795:DGEO_RS00955
uniprot id: Q1J2N7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

319795:DGEO RS00885
gene id: 319795:DGEO_RS00885
uniprot id: Q1J2M4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

319795:DGEO RS09270
gene id: 319795:DGEO_RS09270
uniprot id: Q1IYS1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. NspC subfamily.
messages: Cytoplasm
messages: Homodimer.

319795:DGEO RS10815
gene id: 319795:DGEO_RS10815
uniprot id: Q1IXX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

319795:DGEO RS10005
gene id: 319795:DGEO_RS10005
uniprot id: Q1IYD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

319795:DGEO RS03520
gene id: 319795:DGEO_RS03520
uniprot id: Q1J1Z6
names: Subcellular Location Annotation
messages: Membrane

319795:DGEO RS03065
gene id: 319795:DGEO_RS03065
uniprot id: Q1J287
names: Similarity
messages: Belongs to the asparaginase 1 family.

319795:DGEO RS07950
gene id: 319795:DGEO_RS07950
uniprot id: Q1IZI6
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

319795:DGEO RS03220
gene id: 319795:DGEO_RS03220
uniprot id: Q1J256
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

319795:DGEO RS03250
gene id: 319795:DGEO_RS03250
uniprot id: Q1J250
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein L14 (rplN).

319795:DGEO RS06540
gene id: 319795:DGEO_RS06540
uniprot id: Q1J0B7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

319795:DGEO RS09405
gene id: 319795:DGEO_RS09405
uniprot id: Q1IYP4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

319795:DGEO RS06800
gene id: 319795:DGEO_RS06800
uniprot id: Q1J064
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

319795:DGEO RS03950
gene id: 319795:DGEO_RS03950
uniprot id: Q1J1R4
names: Similarity
messages: Belongs to the UPF0047 family.

319795:DGEO RS03235
gene id: 319795:DGEO_RS03235
uniprot id: Q1J253
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

319795:DGEO RS00720
gene id: 319795:DGEO_RS00720
uniprot id: Q1J2J2
names: Similarity
messages: Belongs to the FGGY kinase family.

319795:DGEO RS02080
gene id: 319795:DGEO_RS02080
uniprot id: Q1J3B7
names: Similarity
messages: Belongs to the ArsC family.

319795:DGEO RS02920
gene id: 319795:DGEO_RS02920
uniprot id: Q1J2B4
names: Similarity
messages: Belongs to the SAICAR synthetase family.

319795:DGEO RS12155
gene id: 319795:DGEO_RS12155
uniprot id: Q1IX61
names: Similarity
messages: Belongs to the WrbA family.

319795:DGEO RS10785
gene id: 319795:DGEO_RS10785
uniprot id: Q1IXX9
names: Subcellular Location Annotation
messages: Membrane

319795:DGEO RS05510
gene id: 319795:DGEO_RS05510
uniprot id: Q1J0W5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

319795:DGEO RS11385
gene id: 319795:DGEO_RS11385
uniprot id: Q1IXL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial secretin family.
messages: Cell outer membrane

319795:DGEO RS13055
gene id: 319795:DGEO_RS13055
uniprot id: Q1IWN9
names: Subcellular Location Annotation
messages: Membrane

319795:DGEO RS08495
gene id: 319795:DGEO_RS08495
uniprot id: Q1IZ75
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate.
messages: Cytoplasm

319795:DGEO RS01350
gene id: 319795:DGEO_RS01350
uniprot id: Q1J2W8
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

319795:DGEO RS07005
gene id: 319795:DGEO_RS07005
uniprot id: Q1J022
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Monomer.

319795:DGEO RS13560
gene id: 319795:DGEO_RS13560
uniprot id: Q1IWD8
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

319795:DGEO RS11660
gene id: 319795:DGEO_RS11660
uniprot id: Q1IXF7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

319795:DGEO RS12520
gene id: 319795:DGEO_RS12520
uniprot id: Q1IWZ1
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

319795:DGEO RS00415
gene id: 319795:DGEO_RS00415
uniprot id: Q1J3V5
names: Function
names: Similarity
messages: Belongs to the NanE family.
messages: Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P).

319795:DGEO RS13745
gene id: 319795:DGEO_RS13745
uniprot id: Q1IWA2
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

319795:DGEO RS11020
gene id: 319795:DGEO_RS11020
uniprot id: Q1IXT2
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

319795:DGEO RS04420
gene id: 319795:DGEO_RS04420
uniprot id: Q1J1H5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Cell membrane
messages: Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate across the membrane.

319795:DGEO RS12100
gene id: 319795:DGEO_RS12100
uniprot id: Q1IX71
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

319795:DGEO RS06380
gene id: 319795:DGEO_RS06380
uniprot id: Q1J0E9
names: Subcellular Location Annotation
messages: Membrane

319795:DGEO RS04850
gene id: 319795:DGEO_RS04850
uniprot id: Q1J195
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

319795:DGEO RS12500
gene id: 319795:DGEO_RS12500
uniprot id: Q1IWZ5
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

319795:DGEO RS03680
gene id: 319795:DGEO_RS03680
uniprot id: Q1J1W6
names: Subcellular Location Annotation
messages: Membrane

319795:DGEO RS05340
gene id: 319795:DGEO_RS05340
uniprot id: Q1J0Z8
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

319795:DGEO RS02980
gene id: 319795:DGEO_RS02980
uniprot id: Q1J2A2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

319795:DGEO RS00295
gene id: 319795:DGEO_RS00295
uniprot id: Q1J3T1
names: Similarity
messages: Belongs to the extradiol ring-cleavage dioxygenase family.

319795:DGEO RS06295
gene id: 319795:DGEO_RS06295
uniprot id: Q1J0G6
names: Similarity
messages: Belongs to the Skp family.

319795:DGEO RS08850
gene id: 319795:DGEO_RS08850
uniprot id: Q1IZ04
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

319795:DGEO RS15550
gene id: 319795:DGEO_RS15550
uniprot id: A8ZRN9
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

319795:DGEO RS05360
gene id: 319795:DGEO_RS05360
uniprot id: Q1J0Z4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

319795:DGEO RS01995
gene id: 319795:DGEO_RS01995
uniprot id: Q1J3A1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

319795:DGEO RS12095
gene id: 319795:DGEO_RS12095
uniprot id: Q1IX72
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

319795:DGEO RS06315
gene id: 319795:DGEO_RS06315
uniprot id: Q1J0G2
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

319795:DGEO RS14250
gene id: 319795:DGEO_RS14250
uniprot id: Q1IW07
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

319795:DGEO RS13105
gene id: 319795:DGEO_RS13105
uniprot id: Q1IWN0
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

319795:DGEO RS01890
gene id: 319795:DGEO_RS01890
uniprot id: Q1J380
names: Subcellular Location Annotation
messages: Membrane

319795:DGEO RS07935
gene id: 319795:DGEO_RS07935
uniprot id: Q1IZI9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

319795:DGEO RS02870
gene id: 319795:DGEO_RS02870
uniprot id: Q1J2C4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
messages: Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
messages: Homodimer.

319795:DGEO RS10335
gene id: 319795:DGEO_RS10335
uniprot id: Q1IY65
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

319795:DGEO RS02600
gene id: 319795:DGEO_RS02600
uniprot id: Q1J2H7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

319795:DGEO RS12835
gene id: 319795:DGEO_RS12835
uniprot id: Q1IWT2
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

319795:DGEO RS13185
gene id: 319795:DGEO_RS13185
uniprot id: Q1IWL4
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

319795:DGEO RS05950
gene id: 319795:DGEO_RS05950
uniprot id: Q1J0N3
names: Similarity
messages: Belongs to the PstS family.

319795:DGEO RS11190
gene id: 319795:DGEO_RS11190
uniprot id: Q1IXP9
names: Subcellular Location Annotation
messages: Membrane

319795:DGEO RS08655
gene id: 319795:DGEO_RS08655
uniprot id: Q1IZ43
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

319795:DGEO RS02915
gene id: 319795:DGEO_RS02915
uniprot id: Q1J2B5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

319795:DGEO RS04090
gene id: 319795:DGEO_RS04090
uniprot id: Q1J1N6
names: Domain
names: Function
names: Induction
names: Subunit
messages: Contains a novel ssDNA-binding fold, which is structurally and topologically distinct from the OB-fold universally found in standard SSB proteins. The disordered C-terminus of DdrB may mediate interactions with other proteins important for DNA damage recovery.
messages: Homopentamer; arranged in a ring-structure.
messages: Induced to high levels following extreme ionizing radiation exposure. Also highly induced in response to desiccation stress (By similarity).
messages: ssDNA-binding protein that probably contributes to the ionizing radiation resistance of D.geothermalis. Plays a role in DNA repair and genome reconstitution, in a RecA-independent process, and is necessary for recovery from severe genomic fragmentation as a result of exposure to severe levels of ionizing radiation (Probable). Binds single-stranded DNA but not duplex DNA.

319795:DGEO RS04075
gene id: 319795:DGEO_RS04075
uniprot id: Q1J1N9
names: Cofactor
names: Similarity
messages: Belongs to the arginase family.
messages: Binds 2 manganese ions per subunit.

319795:DGEO RS10500
gene id: 319795:DGEO_RS10500
uniprot id: Q1IY33
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.

319795:DGEO RS05705
gene id: 319795:DGEO_RS05705
uniprot id: Q1J0S7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

319795:DGEO RS11955
gene id: 319795:DGEO_RS11955
uniprot id: Q1IXA0
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

319795:DGEO RS05395
gene id: 319795:DGEO_RS05395
uniprot id: Q1J0Y7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

319795:DGEO RS07180
gene id: 319795:DGEO_RS07180
uniprot id: Q1IZY8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

319795:DGEO RS03275
gene id: 319795:DGEO_RS03275
uniprot id: Q1J245
names: Similarity
messages: Belongs to the UPF0173 family.

319795:DGEO RS05895
gene id: 319795:DGEO_RS05895
uniprot id: Q1J0P0
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

319795:DGEO RS10405
gene id: 319795:DGEO_RS10405
uniprot id: Q1IY51
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

319795:DGEO RS05430
gene id: 319795:DGEO_RS05430
uniprot id: Q1J0Y1
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

319795:DGEO RS06040
gene id: 319795:DGEO_RS06040
uniprot id: Q1J0L5
names: Similarity
messages: Belongs to the disproportionating enzyme family.

319795:DGEO RS06575
gene id: 319795:DGEO_RS06575
uniprot id: Q1J0A9
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

319795:DGEO RS14020
gene id: 319795:DGEO_RS14020
uniprot id: Q1IW50
names: Similarity
messages: Belongs to the UbiD family.

319795:DGEO RS08140
gene id: 319795:DGEO_RS08140
uniprot id: Q1IZE6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

319795:DGEO RS09860
gene id: 319795:DGEO_RS09860
uniprot id: Q1IYF7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

319795:DGEO RS06545
gene id: 319795:DGEO_RS06545
uniprot id: Q1J0B6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

319795:DGEO RS07785
gene id: 319795:DGEO_RS07785
uniprot id: Q1IZM0
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

319795:DGEO RS02255
gene id: 319795:DGEO_RS02255
uniprot id: Q1J3F4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.

319795:DGEO RS09070
gene id: 319795:DGEO_RS09070
uniprot id: Q1IYV9
names: Similarity
messages: Belongs to the universal stress protein A family.

319795:DGEO RS14515
gene id: 319795:DGEO_RS14515
uniprot id: Q1IVV5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

319795:DGEO RS04310
gene id: 319795:DGEO_RS04310
uniprot id: Q1J1J8
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

319795:DGEO RS06770
gene id: 319795:DGEO_RS06770
uniprot id: Q1J070
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

319795:DGEO RS08870
gene id: 319795:DGEO_RS08870
uniprot id: Q1IYZ9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

319795:DGEO RS12855
gene id: 319795:DGEO_RS12855
uniprot id: Q1IWS8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

319795:DGEO RS07230
gene id: 319795:DGEO_RS07230
uniprot id: Q1IZX8
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

319795:DGEO RS15555
gene id: 319795:DGEO_RS15555
uniprot id: A8ZRP0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

319795:DGEO RS11625
gene id: 319795:DGEO_RS11625
uniprot id: Q1IXG4
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.

319795:DGEO RS04270
gene id: 319795:DGEO_RS04270
uniprot id: Q1J1K3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protease PrsW family.
messages: Cell membrane
messages: Membrane

319795:DGEO RS09755
gene id: 319795:DGEO_RS09755
uniprot id: Q1IYH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

319795:DGEO RS10945
gene id: 319795:DGEO_RS10945
uniprot id: Q1IXU8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

319795:DGEO RS14535
gene id: 319795:DGEO_RS14535
uniprot id: Q1IVV1
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

319795:DGEO RS07385
gene id: 319795:DGEO_RS07385
uniprot id: Q1IZU9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.

319795:DGEO RS02360
gene id: 319795:DGEO_RS02360
uniprot id: Q1J3H8
names: Activity Regulation
names: Caution
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

319795:DGEO RS03725
gene id: 319795:DGEO_RS03725
uniprot id: Q1J1V7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

319795:DGEO RS07145
gene id: 319795:DGEO_RS07145
uniprot id: Q1IZZ5
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.

319795:DGEO RS05955
gene id: 319795:DGEO_RS05955
uniprot id: Q1J0N2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

319795:DGEO RS02565
gene id: 319795:DGEO_RS02565
uniprot id: Q1J3M0
names: Similarity
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.

319795:DGEO RS11990
gene id: 319795:DGEO_RS11990
uniprot id: Q1IX93
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Monomer.

319795:DGEO RS13960
gene id: 319795:DGEO_RS13960
uniprot id: Q1IW59
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

319795:DGEO RS05880
gene id: 319795:DGEO_RS05880
uniprot id: Q1J0P3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

319795:DGEO RS02090
gene id: 319795:DGEO_RS02090
uniprot id: Q1J3B9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

319795:DGEO RS04225
gene id: 319795:DGEO_RS04225
uniprot id: Q1J1L2
names: Subcellular Location Annotation
messages: Membrane

319795:DGEO RS02875
gene id: 319795:DGEO_RS02875
uniprot id: Q1J2C3
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).

319795:DGEO RS05965
gene id: 319795:DGEO_RS05965
uniprot id: Q1J0N0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.
messages: Cell membrane
messages: Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

319795:DGEO RS12180
gene id: 319795:DGEO_RS12180
uniprot id: Q1IX56
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

319795:DGEO RS05605
gene id: 319795:DGEO_RS05605
uniprot id: Q1J0U6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphopentomutase family.
messages: Binds 1 or 2 manganese ions.
messages: Cytoplasm
messages: Phosphotransfer between the C1 and C5 carbon atoms of pentose.

319795:DGEO RS07120
gene id: 319795:DGEO_RS07120
uniprot id: Q1J000
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

319795:DGEO RS13860
gene id: 319795:DGEO_RS13860
uniprot id: Q1IW79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

319795:DGEO RS12660
gene id: 319795:DGEO_RS12660
uniprot id: Q1IWW3
names: Similarity
messages: Belongs to the peptidase M16 family.

319795:DGEO RS14110
gene id: 319795:DGEO_RS14110
uniprot id: Q1IW34
names: Similarity
messages: Belongs to the aminoglycoside phosphotransferase family.

319795:DGEO RS12530
gene id: 319795:DGEO_RS12530
uniprot id: Q1IWY9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

319795:DGEO RS06365
gene id: 319795:DGEO_RS06365
uniprot id: Q1J0F2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

319795:DGEO RS07025
gene id: 319795:DGEO_RS07025
uniprot id: Q1J018
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

319795:DGEO RS11575
gene id: 319795:DGEO_RS11575
uniprot id: Q1IXH3
names: Similarity
messages: Belongs to the ETF-QO/FixC family.

319795:DGEO RS13285
gene id: 319795:DGEO_RS13285
uniprot id: Q1IWJ3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. MqnE family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3-[(1-carboxyvinyl)oxy]benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate.

319795:DGEO RS02835
gene id: 319795:DGEO_RS02835
uniprot id: Q1J2D1
names: Similarity
messages: Belongs to the CFA/CMAS family.

319795:DGEO RS04045
gene id: 319795:DGEO_RS04045
uniprot id: Q1J1P5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

319795:DGEO RS07675
gene id: 319795:DGEO_RS07675
uniprot id: Q1IZP2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

319795:DGEO RS03255
gene id: 319795:DGEO_RS03255
uniprot id: Q1J249
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

319795:DGEO RS00780
gene id: 319795:DGEO_RS00780
uniprot id: Q1J2K4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpC family.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

319795:DGEO RS05685
gene id: 319795:DGEO_RS05685
uniprot id: Q1J0T1
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Dimer of large and small chains.

319795:DGEO RS05370
gene id: 319795:DGEO_RS05370
uniprot id: Q1J0Z2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 13 family.
messages: Cytoplasm

319795:DGEO RS02950
gene id: 319795:DGEO_RS02950
uniprot id: Q1J2A8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

319795:DGEO RS06845
gene id: 319795:DGEO_RS06845
uniprot id: Q1J054
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

319795:DGEO RS09320
gene id: 319795:DGEO_RS09320
uniprot id: Q1IYR1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
messages: Homodimer.

319795:DGEO RS01955
gene id: 319795:DGEO_RS01955
uniprot id: Q1J393
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

319795:DGEO RS13465
gene id: 319795:DGEO_RS13465
uniprot id: Q1IWF7
names: Similarity
messages: Belongs to the peptidase S58 family.

319795:DGEO RS04515
gene id: 319795:DGEO_RS04515
uniprot id: Q1J1F7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Plays an essential role in type IV pili and type II pseudopili formation by proteolytically removing the leader sequence from substrate proteins and subsequently monomethylating the alpha-amino group of the newly exposed N-terminal phenylalanine.

319795:DGEO RS06530
gene id: 319795:DGEO_RS06530
uniprot id: Q1J0B9
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

319795:DGEO RS11055
gene id: 319795:DGEO_RS11055
uniprot id: Q1IXS5
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

319795:DGEO RS01550
gene id: 319795:DGEO_RS01550
uniprot id: Q1J307
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

319795:DGEO RS04145
gene id: 319795:DGEO_RS04145
uniprot id: Q1J1M6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

319795:DGEO RS08220
gene id: 319795:DGEO_RS08220
uniprot id: Q1IZC9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glutaminase PdxT/SNO family.
messages: Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
messages: In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer.

319795:DGEO RS06500
gene id: 319795:DGEO_RS06500
uniprot id: Q1J0C5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell membrane
messages: Membrane

319795:DGEO RS05725
gene id: 319795:DGEO_RS05725
uniprot id: Q1J0S3
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

319795:DGEO RS04895
gene id: 319795:DGEO_RS04895
uniprot id: Q1J186
names: Similarity
messages: Belongs to the band 7/mec-2 family. Flotillin subfamily.

319795:DGEO RS08700
gene id: 319795:DGEO_RS08700
uniprot id: Q1IZ34
names: Similarity
messages: Belongs to the glutamine synthetase family.

319795:DGEO RS11485
gene id: 319795:DGEO_RS11485
uniprot id: Q1IXJ1
names: Subcellular Location Annotation
messages: Membrane

319795:DGEO RS06535
gene id: 319795:DGEO_RS06535
uniprot id: Q1J0B8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0382 family.
messages: Membrane

319795:DGEO RS08380
gene id: 319795:DGEO_RS08380
uniprot id: Q1IZ98
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

319795:DGEO RS07980
gene id: 319795:DGEO_RS07980
uniprot id: Q1IZH8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

319795:DGEO RS04755
gene id: 319795:DGEO_RS04755
uniprot id: Q1J1B1
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.

319795:DGEO RS11410
gene id: 319795:DGEO_RS11410
uniprot id: Q1IXK5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

319795:DGEO RS11320
gene id: 319795:DGEO_RS11320
uniprot id: Q1IXM3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm
messages: Homodimer.

319795:DGEO RS10800
gene id: 319795:DGEO_RS10800
uniprot id: Q1IXX6
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

319795:DGEO RS10135
gene id: 319795:DGEO_RS10135
uniprot id: Q1IYA4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

319795:DGEO RS10155
gene id: 319795:DGEO_RS10155
uniprot id: Q1IYA0
names: Similarity
messages: Belongs to the peptidase M29 family.

319795:DGEO RS05680
gene id: 319795:DGEO_RS05680
uniprot id: Q1J0T2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.

319795:DGEO RS02355
gene id: 319795:DGEO_RS02355
uniprot id: Q1J3H7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

319795:DGEO RS06750
gene id: 319795:DGEO_RS06750
uniprot id: Q1J074
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit A family.

319795:DGEO RS08195
gene id: 319795:DGEO_RS08195
uniprot id: Q1IZD4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 3B subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

319795:DGEO RS14680
gene id: 319795:DGEO_RS14680
uniprot id: A8ZR58
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

319795:DGEO RS06965
gene id: 319795:DGEO_RS06965
uniprot id: Q1J031
names: Cofactor
messages: Binds 1 FAD per subunit.

319795:DGEO RS15535
gene id: 319795:DGEO_RS15535
uniprot id: A8ZRN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

319795:DGEO RS07750
gene id: 319795:DGEO_RS07750
uniprot id: Q1IZM7
names: Similarity
messages: Belongs to the Nudix hydrolase family.

319795:DGEO RS12020
gene id: 319795:DGEO_RS12020
uniprot id: Q1IX87
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

319795:DGEO RS10900
gene id: 319795:DGEO_RS10900
uniprot id: Q1IXV7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

319795:DGEO RS04875
gene id: 319795:DGEO_RS04875
uniprot id: Q1J190
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C15 family.
messages: Cytoplasm
messages: Removes 5-oxoproline from various penultimate amino acid residues except L-proline.

319795:DGEO RS15725
gene id: 319795:DGEO_RS15725
uniprot id: Q1IYG2
names: Subcellular Location Annotation
messages: Cytoplasm

319795:DGEO RS01930
gene id: 319795:DGEO_RS01930
uniprot id: Q1J388
names: Similarity
messages: Belongs to the TPP enzyme family.

319795:DGEO RS02650
gene id: 319795:DGEO_RS02650
uniprot id: Q1J2G7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

319795:DGEO RS06840
gene id: 319795:DGEO_RS06840
uniprot id: Q1J055
names: Activity Regulation
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.

319795:DGEO RS13230
gene id: 319795:DGEO_RS13230
uniprot id: Q1IWK4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

319795:DGEO RS05620
gene id: 319795:DGEO_RS05620
uniprot id: Q1J0U3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

319795:DGEO RS13635
gene id: 319795:DGEO_RS13635
uniprot id: Q1IWC4
names: Subcellular Location Annotation
messages: Membrane

319795:DGEO RS13610
gene id: 319795:DGEO_RS13610
uniprot id: Q1IWC9
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 2 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

319795:DGEO RS11450
gene id: 319795:DGEO_RS11450
uniprot id: Q1IXJ7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

319795:DGEO RS08190
gene id: 319795:DGEO_RS08190
uniprot id: Q1IZD5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

319795:DGEO RS03615
gene id: 319795:DGEO_RS03615
uniprot id: Q1J1X9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uridine kinase family.
messages: Cytoplasm

319795:DGEO RS05350
gene id: 319795:DGEO_RS05350
uniprot id: Q1J0Z6
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

319795:DGEO RS10920
gene id: 319795:DGEO_RS10920
uniprot id: Q1IXV3
names: Similarity
messages: Belongs to the leucine-binding protein family.

319795:DGEO RS10280
gene id: 319795:DGEO_RS10280
uniprot id: Q1IY76
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

319795:DGEO RS02615
gene id: 319795:DGEO_RS02615
uniprot id: Q1J2H4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

319795:DGEO RS04905
gene id: 319795:DGEO_RS04905
uniprot id: Q1J184
names: Function
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family. Futalosine hydrolase subfamily.
messages: Catalyzes the hydrolysis of futalosine (FL) to dehypoxanthine futalosine (DHFL) and hypoxanthine, a step in the biosynthesis of menaquinone (MK, vitamin K2).

319795:DGEO RS12015
gene id: 319795:DGEO_RS12015
uniprot id: Q1IX88
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

319795:DGEO RS07455
gene id: 319795:DGEO_RS07455
uniprot id: Q1IZT5
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

319795:DGEO RS07925
gene id: 319795:DGEO_RS07925
uniprot id: Q1IZJ1
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

319795:DGEO RS09340
gene id: 319795:DGEO_RS09340
uniprot id: Q1IYQ7
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

319795:DGEO RS08595
gene id: 319795:DGEO_RS08595
uniprot id: Q1IZ55
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

319795:DGEO RS14125
gene id: 319795:DGEO_RS14125
uniprot id: Q1IW31
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

319795:DGEO RS03370
gene id: 319795:DGEO_RS03370
uniprot id: Q1J226
names: Similarity
messages: Belongs to the universal stress protein A family.

319795:DGEO RS05650
gene id: 319795:DGEO_RS05650
uniprot id: Q1J0T8
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruD family.
messages: Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.

319795:DGEO RS04710
gene id: 319795:DGEO_RS04710
uniprot id: Q1J1C0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

319795:DGEO RS04795
gene id: 319795:DGEO_RS04795
uniprot id: Q1J1A4
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

319795:DGEO RS05215
gene id: 319795:DGEO_RS05215
uniprot id: Q1J123
names: Similarity
messages: Belongs to the acylphosphatase family.

319795:DGEO RS09010
gene id: 319795:DGEO_RS09010
uniprot id: Q1IYX1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

319795:DGEO RS11230
gene id: 319795:DGEO_RS11230
uniprot id: Q1IXP1
names: Similarity
messages: Belongs to the peptidase M1 family.

319795:DGEO RS08465
gene id: 319795:DGEO_RS08465
uniprot id: Q1IZ81
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

319795:DGEO RS09830
gene id: 319795:DGEO_RS09830
uniprot id: Q1IYG3
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.

319795:DGEO RS02885
gene id: 319795:DGEO_RS02885
uniprot id: Q1J2C1
names: Function
names: Similarity
messages: Belongs to the trehalose phosphatase family.
messages: Removes the phosphate from trehalose 6-phosphate to produce free trehalose.

319795:DGEO RS13865
gene id: 319795:DGEO_RS13865
uniprot id: Q1IW78
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

319795:DGEO RS02840
gene id: 319795:DGEO_RS02840
uniprot id: Q1J2D0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the CobB/CobQ family.
messages: Involved in acetate metabolism.
messages: The N-terminal region seems to be important for proper quaternary structure. The C-terminal region contains the substrate-binding site (By similarity).

319795:DGEO RS10730
gene id: 319795:DGEO_RS10730
uniprot id: Q1IXY9
names: Similarity
messages: Belongs to the PGI/PMI family.

319795:DGEO RS05010
gene id: 319795:DGEO_RS05010
uniprot id: Q1J163
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

319795:DGEO RS13900
gene id: 319795:DGEO_RS13900
uniprot id: Q1IW71
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

319795:DGEO RS02455
gene id: 319795:DGEO_RS02455
uniprot id: Q1J3J7
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

319795:DGEO RS05025
gene id: 319795:DGEO_RS05025
uniprot id: Q1J160
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

319795:DGEO RS13475
gene id: 319795:DGEO_RS13475
uniprot id: Q1IWF5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

319795:DGEO RS01925
gene id: 319795:DGEO_RS01925
uniprot id: Q1J387
names: Similarity
messages: Belongs to the hyi family.

319795:DGEO RS07370
gene id: 319795:DGEO_RS07370
uniprot id: Q1IZV2
names: Similarity
messages: Belongs to the TelA family.

319795:DGEO RS13050
gene id: 319795:DGEO_RS13050
uniprot id: Q1IWP0
names: Function
names: Similarity
messages: Belongs to the V-ATPase E subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

319795:DGEO RS11355
gene id: 319795:DGEO_RS11355
uniprot id: Q1IXL6
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

319795:DGEO RS02605
gene id: 319795:DGEO_RS02605
uniprot id: Q1J2H6
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

319795:DGEO RS01385
gene id: 319795:DGEO_RS01385
uniprot id: Q1J2X5
names: Similarity
messages: Belongs to the bacterial solute-binding protein 1 family.

319795:DGEO RS13655
gene id: 319795:DGEO_RS13655
uniprot id: Q1IWC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

319795:DGEO RS15615
gene id: 319795:DGEO_RS15615
uniprot id: Q1J2Y4
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

319795:DGEO RS09915
gene id: 319795:DGEO_RS09915
uniprot id: Q1IYE8
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

319795:DGEO RS08690
gene id: 319795:DGEO_RS08690
uniprot id: Q1IZ36
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

319795:DGEO RS02435
gene id: 319795:DGEO_RS02435
uniprot id: Q1J3J3
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A lyase-type mechanism (elimination/hydration) is suggested for the cleavage of the lactyl ether bond of MurNAc 6-phosphate, with the formation of an alpha,beta-unsaturated aldehyde intermediate with (E)-stereochemistry, followed by the syn addition of water to give product.
messages: Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
messages: Homodimer.
messages: Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate.

319795:DGEO RS11490
gene id: 319795:DGEO_RS11490
uniprot id: Q1IXJ0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

319795:DGEO RS09745
gene id: 319795:DGEO_RS09745
uniprot id: Q1IYH9
names: Similarity
messages: Belongs to the sulfate adenylyltransferase family.

319795:DGEO RS06910
gene id: 319795:DGEO_RS06910
uniprot id: Q1J041
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

319795:DGEO RS05660
gene id: 319795:DGEO_RS05660
uniprot id: Q1J0T6
names: Function
names: Similarity
messages: Belongs to the MoaB/Mog family.
messages: May be involved in the biosynthesis of molybdopterin.

319795:DGEO RS06425
gene id: 319795:DGEO_RS06425
uniprot id: Q1J0E0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

319795:DGEO RS11960
gene id: 319795:DGEO_RS11960
uniprot id: Q1IX99
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

319795:DGEO RS13705
gene id: 319795:DGEO_RS13705
uniprot id: Q1IWB0
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Homodimer.

319795:DGEO RS09650
gene id: 319795:DGEO_RS09650
uniprot id: Q1IYJ9
names: Subcellular Location Annotation
messages: Membrane

319795:DGEO RS03975
gene id: 319795:DGEO_RS03975
uniprot id: Q1J1Q9
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

319795:DGEO RS00895
gene id: 319795:DGEO_RS00895
uniprot id: Q1J2M6
names: Similarity
messages: Belongs to the glycosyl hydrolase 42 family.

319795:DGEO RS13575
gene id: 319795:DGEO_RS13575
uniprot id: Q1IWD5
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

319795:DGEO RS12690
gene id: 319795:DGEO_RS12690
uniprot id: Q1IWV7
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

319795:DGEO RS09640
gene id: 319795:DGEO_RS09640
uniprot id: Q1IYK1
names: Similarity
messages: Belongs to the peptidase C40 family.

319795:DGEO RS13410
gene id: 319795:DGEO_RS13410
uniprot id: Q1IWG8
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

319795:DGEO RS13300
gene id: 319795:DGEO_RS13300
uniprot id: Q1IWJ0
names: Similarity
messages: Belongs to the DinB family.

319795:DGEO RS12195
gene id: 319795:DGEO_RS12195
uniprot id: Q1IX53
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 2 lipoyl cofactors covalently.
messages: Forms a 24-polypeptide structural core with octahedral symmetry.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

319795:DGEO RS13480
gene id: 319795:DGEO_RS13480
uniprot id: Q1IWF4
names: Similarity
messages: Belongs to the CinA family.

319795:DGEO RS10835
gene id: 319795:DGEO_RS10835
uniprot id: Q1IXW9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

319795:DGEO RS14270
gene id: 319795:DGEO_RS14270
uniprot id: Q1IW03
names: Similarity
messages: Belongs to the Ahb/Nir family.

319795:DGEO RS13320
gene id: 319795:DGEO_RS13320
uniprot id: Q1IWI6
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

319795:DGEO RS04555
gene id: 319795:DGEO_RS04555
uniprot id: Q1J1E9
names: Subcellular Location Annotation
messages: Membrane

319795:DGEO RS12030
gene id: 319795:DGEO_RS12030
uniprot id: Q1IX85
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

319795:DGEO RS05085
gene id: 319795:DGEO_RS05085
uniprot id: Q1J148
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmG family. TrmFO subfamily.
messages: Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
messages: Cytoplasm

319795:DGEO RS09600
gene id: 319795:DGEO_RS09600
uniprot id: Q1IYK8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IPP isomerase type 2 family.
messages: Cytoplasm
messages: Homooctamer. Dimer of tetramers.
messages: Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

319795:DGEO RS07020
gene id: 319795:DGEO_RS07020
uniprot id: Q1J019
names: Similarity
messages: Belongs to the peptidase C56 family.

319795:DGEO RS07320
gene id: 319795:DGEO_RS07320
uniprot id: Q1IZW0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 15 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

319795:DGEO RS01565
gene id: 319795:DGEO_RS01565
uniprot id: Q1J310
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Catalyzes the phosphorylation of D-xylulose to D-xylulose 5-phosphate.

319795:DGEO RS09645
gene id: 319795:DGEO_RS09645
uniprot id: Q1IYK0
names: Subcellular Location Annotation
messages: Membrane

319795:DGEO RS07765
gene id: 319795:DGEO_RS07765
uniprot id: Q1IZM4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

319795:DGEO RS06755
gene id: 319795:DGEO_RS06755
uniprot id: Q1J073
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

319795:DGEO RS12035
gene id: 319795:DGEO_RS12035
uniprot id: Q1IX84
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

319795:DGEO RS00600
gene id: 319795:DGEO_RS00600
uniprot id: Q1J3Y4
names: Function
names: Similarity
messages: Belongs to the CbiD family.
messages: Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.

319795:DGEO RS00940
gene id: 319795:DGEO_RS00940
uniprot id: Q1J2N5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

319795:DGEO RS08905
gene id: 319795:DGEO_RS08905
uniprot id: Q1IYZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmE/CycJ family.
messages: Cell membrane
messages: Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.

319795:DGEO RS04790
gene id: 319795:DGEO_RS04790
uniprot id: Q1J1A5
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

319795:DGEO RS09110
gene id: 319795:DGEO_RS09110
uniprot id: Q1IYV2
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

319795:DGEO RS05850
gene id: 319795:DGEO_RS05850
uniprot id: Q1J0P9
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

319795:DGEO RS00725
gene id: 319795:DGEO_RS00725
uniprot id: Q1J2J3
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

319795:DGEO RS07720
gene id: 319795:DGEO_RS07720
uniprot id: Q1IZN3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Monomer.

319795:DGEO RS14770
gene id: 319795:DGEO_RS14770
uniprot id: A8ZR47
names: Function
messages: Involved in the transposition of the insertion sequence.

319795:DGEO RS13505
gene id: 319795:DGEO_RS13505
uniprot id: Q1IWE9
names: Similarity
messages: Belongs to the Fur family.

319795:DGEO RS06660
gene id: 319795:DGEO_RS06660
uniprot id: Q1J092
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

319795:DGEO RS05860
gene id: 319795:DGEO_RS05860
uniprot id: Q1J0P7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

319795:DGEO RS01880
gene id: 319795:DGEO_RS01880
uniprot id: Q1J378
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

319795:DGEO RS05375
gene id: 319795:DGEO_RS05375
uniprot id: Q1J0Z1
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

319795:DGEO RS07685
gene id: 319795:DGEO_RS07685
uniprot id: Q1IZP0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

319795:DGEO RS03915
gene id: 319795:DGEO_RS03915
uniprot id: Q1J1S0
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

319795:DGEO RS13685
gene id: 319795:DGEO_RS13685
uniprot id: Q1IWB4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

319795:DGEO RS14090
gene id: 319795:DGEO_RS14090
uniprot id: Q1IW39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

319795:DGEO RS02830
gene id: 319795:DGEO_RS02830
uniprot id: Q1J2D2
names: Subcellular Location Annotation
messages: Membrane

319795:DGEO RS12140
gene id: 319795:DGEO_RS12140
uniprot id: Q1IX63
names: Similarity
messages: Belongs to the FBPase class 2 family.

319795:DGEO RS00860
gene id: 319795:DGEO_RS00860
uniprot id: Q1J2L9
names: Similarity
messages: Belongs to the peptidase S8 family.

319795:DGEO RS01635
gene id: 319795:DGEO_RS01635
uniprot id: Q1J327
names: Subcellular Location Annotation
messages: Membrane

319795:DGEO RS10775
gene id: 319795:DGEO_RS10775
uniprot id: Q1IXY1
names: Similarity
messages: Belongs to the PHP hydrolase family. HisK subfamily.

319795:DGEO RS06325
gene id: 319795:DGEO_RS06325
uniprot id: Q1J0G0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gluconeogenesis factor family.
messages: Cytoplasm
messages: Required for morphogenesis under gluconeogenic growth conditions.

319795:DGEO RS08500
gene id: 319795:DGEO_RS08500
uniprot id: Q1IZ74
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

319795:DGEO RS03960
gene id: 319795:DGEO_RS03960
uniprot id: Q1J1R2
names: Cofactor
names: Similarity
messages: Belongs to the peptidase S45 family.
messages: Binds 1 Ca(2+) ion per dimer.

319795:DGEO RS02845
gene id: 319795:DGEO_RS02845
uniprot id: Q1J2C9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

319795:DGEO RS02545
gene id: 319795:DGEO_RS02545
uniprot id: Q1J3L6
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

319795:DGEO RS09115
gene id: 319795:DGEO_RS09115
uniprot id: Q1IYV1
names: Cofactor
messages: Can also use Mn(2+) ion.

319795:DGEO RS12280
gene id: 319795:DGEO_RS12280
uniprot id: Q1IX36
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

319795:DGEO RS11885
gene id: 319795:DGEO_RS11885
uniprot id: Q1IXB4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

319795:DGEO RS10895
gene id: 319795:DGEO_RS10895
uniprot id: Q1IXV8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

319795:DGEO RS06010
gene id: 319795:DGEO_RS06010
uniprot id: Q1J0M1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PEPCase type 1 family.
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
messages: Homotetramer.

319795:DGEO RS12105
gene id: 319795:DGEO_RS12105
uniprot id: Q1IX70
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

319795:DGEO RS07140
gene id: 319795:DGEO_RS07140
uniprot id: Q1IZZ6
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

319795:DGEO RS13235
gene id: 319795:DGEO_RS13235
uniprot id: Q1IWK3
names: Subcellular Location Annotation
messages: Membrane

319795:DGEO RS13990
gene id: 319795:DGEO_RS13990
uniprot id: Q1IW56
names: Function
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the 2'-O methylation of guanosine at position 18 in tRNA.

319795:DGEO RS11810
gene id: 319795:DGEO_RS11810
uniprot id: Q1IXC9
names: Function
names: Similarity
messages: Belongs to the MqnA/MqnD family. MqnD subfamily.
messages: Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).

319795:DGEO RS02610
gene id: 319795:DGEO_RS02610
uniprot id: Q1J2H5
names: Similarity
messages: Belongs to the pyruvate kinase family.

319795:DGEO RS09780
gene id: 319795:DGEO_RS09780
uniprot id: Q1IYH3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. LysJ subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the transfer of the amino group of L-glutamate to [LysW]-aminoadipate 6-semialdehyde, generating [LysW]-gamma-L-lysine.
messages: Cytoplasm
messages: Homodimer.

319795:DGEO RS00675
gene id: 319795:DGEO_RS00675
uniprot id: Q1J2I3
names: Function
names: Similarity
messages: Belongs to the CobT family.
messages: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).

319795:DGEO RS13250
gene id: 319795:DGEO_RS13250
uniprot id: Q1IWK0
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.

319795:DGEO RS06390
gene id: 319795:DGEO_RS06390
uniprot id: Q1J0E7
names: Similarity
messages: Belongs to the leucine-binding protein family.

319795:DGEO RS07240
gene id: 319795:DGEO_RS07240
uniprot id: Q1IZX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

319795:DGEO RS04105
gene id: 319795:DGEO_RS04105
uniprot id: Q1J1N3
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

319795:DGEO RS00345
gene id: 319795:DGEO_RS00345
uniprot id: Q1J3U1
names: Function
names: Similarity
messages: Belongs to the phenylacetyl-CoA ligase family.
messages: Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).

319795:DGEO RS09800
gene id: 319795:DGEO_RS09800
uniprot id: Q1IYG9
names: Similarity
messages: Belongs to the histone deacetylase family.

319795:DGEO RS07680
gene id: 319795:DGEO_RS07680
uniprot id: Q1IZP1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

319795:DGEO RS13630
gene id: 319795:DGEO_RS13630
uniprot id: Q1IWC5
names: Similarity
messages: Belongs to the leucine-binding protein family.

319795:DGEO RS06140
gene id: 319795:DGEO_RS06140
uniprot id: Q1J0J6
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

319795:DGEO RS11475
gene id: 319795:DGEO_RS11475
uniprot id: Q1IXJ3
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

319795:DGEO RS01405
gene id: 319795:DGEO_RS01405
uniprot id: Q1J2X9
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

319795:DGEO RS04260
gene id: 319795:DGEO_RS04260
uniprot id: Q1J1K5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

319795:DGEO RS07825
gene id: 319795:DGEO_RS07825
uniprot id: Q1IZL1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon.

319795:DGEO RS02940
gene id: 319795:DGEO_RS02940
uniprot id: Q1J2B0
names: Similarity
messages: Belongs to the peptidase M29 family.

319795:DGEO RS09885
gene id: 319795:DGEO_RS09885
uniprot id: Q1IYF3
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

319795:DGEO RS05710
gene id: 319795:DGEO_RS05710
uniprot id: Q1J0S6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

319795:DGEO RS09200
gene id: 319795:DGEO_RS09200
uniprot id: Q1IYT4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

319795:DGEO RS04530
gene id: 319795:DGEO_RS04530
uniprot id: Q1J1F4
names: Function
names: Similarity
messages: Belongs to the MinE family.
messages: Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.

319795:DGEO RS00610
gene id: 319795:DGEO_RS00610
uniprot id: Q1J3Y6
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

319795:DGEO RS14075
gene id: 319795:DGEO_RS14075
uniprot id: Q1IW42
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LuxS family.
messages: Binds 1 Fe cation per subunit.
messages: Homodimer.
messages: Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).

319795:DGEO RS14190
gene id: 319795:DGEO_RS14190
uniprot id: Q1IW18
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

319795:DGEO RS03335
gene id: 319795:DGEO_RS03335
uniprot id: Q1J233
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XseA family.
messages: Cytoplasm

319795:DGEO RS05795
gene id: 319795:DGEO_RS05795
uniprot id: Q1J0R0
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PSRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.

319795:DGEO RS15335
gene id: 319795:DGEO_RS15335
uniprot id: A8ZRJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta sliding clamp family.
messages: Cytoplasm

319795:DGEO RS12555
gene id: 319795:DGEO_RS12555
uniprot id: Q1IWY4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell inner membrane
messages: Cell membrane
messages: Forms a complex with MdtI.
messages: Membrane

319795:DGEO RS09310
gene id: 319795:DGEO_RS09310
uniprot id: Q1IYR3
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

319795:DGEO RS11545
gene id: 319795:DGEO_RS11545
uniprot id: Q1IXH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

319795:DGEO RS08395
gene id: 319795:DGEO_RS08395
uniprot id: Q1IZ95
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

319795:DGEO RS00965
gene id: 319795:DGEO_RS00965
uniprot id: Q1J2N9
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

319795:DGEO RS11920
gene id: 319795:DGEO_RS11920
uniprot id: Q1IXA7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

319795:DGEO RS02635
gene id: 319795:DGEO_RS02635
uniprot id: Q1J2H0
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

319795:DGEO RS07940
gene id: 319795:DGEO_RS07940
uniprot id: Q1IZI8
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by GTP. Inhibited by UTP.
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.

319795:DGEO RS00395
gene id: 319795:DGEO_RS00395
uniprot id: Q1J3V1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

319795:DGEO RS07500
gene id: 319795:DGEO_RS07500
uniprot id: Q1IZS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

319795:DGEO RS12640
gene id: 319795:DGEO_RS12640
uniprot id: Q1IWW7
names: Similarity
messages: Belongs to the 6-phosphogluconate dehydrogenase family.

319795:DGEO RS08355
gene id: 319795:DGEO_RS08355
uniprot id: Q1IZA3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

319795:DGEO RS05435
gene id: 319795:DGEO_RS05435
uniprot id: Q1J0Y0
names: Similarity
messages: Belongs to the peptidase S1C family.

319795:DGEO RS02770
gene id: 319795:DGEO_RS02770
uniprot id: Q1J2E4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

319795:DGEO RS13225
gene id: 319795:DGEO_RS13225
uniprot id: Q1IWK5
names: Caution
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

319795:DGEO RS13850
gene id: 319795:DGEO_RS13850
uniprot id: Q1IW81
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

319795:DGEO RS11185
gene id: 319795:DGEO_RS11185
uniprot id: Q1IXQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

319795:DGEO RS02475
gene id: 319795:DGEO_RS02475
uniprot id: Q1J3K1
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

319795:DGEO RS02085
gene id: 319795:DGEO_RS02085
uniprot id: Q1J3B8
names: Subcellular Location Annotation
messages: Membrane

319795:DGEO RS06895
gene id: 319795:DGEO_RS06895
uniprot id: Q1J044
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

319795:DGEO RS12080
gene id: 319795:DGEO_RS12080
uniprot id: Q1IX75
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

319795:DGEO RS07735
gene id: 319795:DGEO_RS07735
uniprot id: Q1IZN0
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

319795:DGEO RS08745
gene id: 319795:DGEO_RS08745
uniprot id: Q1IZ25
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

319795:DGEO RS12050
gene id: 319795:DGEO_RS12050
uniprot id: Q1IX81
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

319795:DGEO RS08695
gene id: 319795:DGEO_RS08695
uniprot id: Q1IZ35
names: Similarity
messages: Belongs to the antibiotic N-acetyltransferase family.

319795:DGEO RS04675
gene id: 319795:DGEO_RS04675
uniprot id: Q1J1C7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

319795:DGEO RS11345
gene id: 319795:DGEO_RS11345
uniprot id: Q1IXL8
names: Similarity
messages: Belongs to the asp23 family.

319795:DGEO RS00790
gene id: 319795:DGEO_RS00790
uniprot id: Q1J2K6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system and for the release of the potassium ions to the cytoplasm.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

319795:DGEO RS05915
gene id: 319795:DGEO_RS05915
uniprot id: Q1IX70
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

319795:DGEO RS10755
gene id: 319795:DGEO_RS10755
uniprot id: Q1IXY5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 2 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

319795:DGEO RS05445
gene id: 319795:DGEO_RS05445
uniprot id: Q1J0X8
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

319795:DGEO RS14480
gene id: 319795:DGEO_RS14480
uniprot id: Q1IVW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. TCR/Tet family.
messages: Membrane

319795:DGEO RS13570
gene id: 319795:DGEO_RS13570
uniprot id: Q1IWD6
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

319795:DGEO RS12265
gene id: 319795:DGEO_RS12265
uniprot id: Q1IX39
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

319795:DGEO RS08530
gene id: 319795:DGEO_RS08530
uniprot id: Q1IZ68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

319795:DGEO RS11865
gene id: 319795:DGEO_RS11865
uniprot id: Q1IXB8
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

319795:DGEO RS12385
gene id: 319795:DGEO_RS12385
uniprot id: Q1IX18
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

319795:DGEO RS06075
gene id: 319795:DGEO_RS06075
uniprot id: Q1J0K9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MinC family.
messages: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.
messages: Interacts with MinD and FtsZ.

319795:DGEO RS03420
gene id: 319795:DGEO_RS03420
uniprot id: Q1J215
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

319795:DGEO RS03120
gene id: 319795:DGEO_RS03120
uniprot id: Q1J276
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

319795:DGEO RS03200
gene id: 319795:DGEO_RS03200
uniprot id: Q1J260
names: Similarity
messages: Belongs to the fatty acid desaturase type 2 family.

319795:DGEO RS12595
gene id: 319795:DGEO_RS12595
uniprot id: Q1IWX6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

319795:DGEO RS03805
gene id: 319795:DGEO_RS03805
uniprot id: Q1J1U1
names: Similarity
messages: Belongs to the peptidase M29 family.

319795:DGEO RS13895
gene id: 319795:DGEO_RS13895
uniprot id: Q1IW72
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

319795:DGEO RS14945
gene id: 319795:DGEO_RS14945
uniprot id: A8ZRB4
names: Similarity
messages: Belongs to the ParB family.

319795:DGEO RS06670
gene id: 319795:DGEO_RS06670
uniprot id: Q1J090
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm

319795:DGEO RS12655
gene id: 319795:DGEO_RS12655
uniprot id: Q1IWW4
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

319795:DGEO RS13590
gene id: 319795:DGEO_RS13590
uniprot id: Q1IWD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

319795:DGEO RS01380
gene id: 319795:DGEO_RS01380
uniprot id: Q1J2X4
names: Similarity
messages: Belongs to the Fur family.

319795:DGEO RS13080
gene id: 319795:DGEO_RS13080
uniprot id: Q1IWN4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

319795:DGEO RS12715
gene id: 319795:DGEO_RS12715
uniprot id: Q1IWV4
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

319795:DGEO RS01555
gene id: 319795:DGEO_RS01555
uniprot id: Q1J308
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

319795:DGEO RS11310
gene id: 319795:DGEO_RS11310
uniprot id: Q1IXM4
names: Subcellular Location Annotation
messages: Membrane

319795:DGEO RS07095
gene id: 319795:DGEO_RS07095
uniprot id: Q1J005
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MsrP family.
messages: Binds 1 Mo-molybdopterin (Mo-MPT) cofactor per subunit.
messages: Heterodimer of a catalytic subunit (MsrP) and a heme-binding subunit (MsrQ).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the MsrPQ system that repairs oxidized cell envelope proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated cell envelope proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide.

319795:DGEO RS12295
gene id: 319795:DGEO_RS12295
uniprot id: Q1IX33
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

319795:DGEO RS15025
gene id: 319795:DGEO_RS15025
uniprot id: A8ZR47
names: Function
messages: Involved in the transposition of the insertion sequence.

319795:DGEO RS11740
gene id: 319795:DGEO_RS11740
uniprot id: Q1IXE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

319795:DGEO RS05145
gene id: 319795:DGEO_RS05145
uniprot id: Q1J137
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

319795:DGEO RS12085
gene id: 319795:DGEO_RS12085
uniprot id: Q1IX74
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

319795:DGEO RS04615
gene id: 319795:DGEO_RS04615
uniprot id: Q1J1D8
names: Function
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 2 subfamily.
messages: Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 2-succinylbenzoate (OSB).

319795:DGEO RS03410
gene id: 319795:DGEO_RS03410
uniprot id: Q1J217
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

319795:DGEO RS01755
gene id: 319795:DGEO_RS01755
uniprot id: Q1J351
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.

319795:DGEO RS09955
gene id: 319795:DGEO_RS09955
uniprot id: Q1IYE0
names: Subcellular Location Annotation
messages: Membrane

319795:DGEO RS02900
gene id: 319795:DGEO_RS02900
uniprot id: Q1J2B8
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

319795:DGEO RS00980
gene id: 319795:DGEO_RS00980
uniprot id: Q1J2P1
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

319795:DGEO RS09160
gene id: 319795:DGEO_RS09160
uniprot id: Q1IYU2
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

319795:DGEO RS04390
gene id: 319795:DGEO_RS04390
uniprot id: Q1J1I0
names: Subcellular Location Annotation
messages: Membrane

319795:DGEO RS10710
gene id: 319795:DGEO_RS10710
uniprot id: Q1IXZ3
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family.

319795:DGEO RS01160
gene id: 319795:DGEO_RS01160
uniprot id: Q1J2S9
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

319795:DGEO RS12060
gene id: 319795:DGEO_RS12060
uniprot id: Q1IX79
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

319795:DGEO RS08845
gene id: 319795:DGEO_RS08845
uniprot id: Q1IZ05
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

319795:DGEO RS00465
gene id: 319795:DGEO_RS00465
uniprot id: Q1J3Z7
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

319795:DGEO RS01445
gene id: 319795:DGEO_RS01445
uniprot id: Q1J2Y8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

319795:DGEO RS07615
gene id: 319795:DGEO_RS07615
uniprot id: Q1IZQ4
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

319795:DGEO RS04680
gene id: 319795:DGEO_RS04680
uniprot id: Q1J1C6
names: Similarity
messages: Belongs to the SCO1/2 family.

319795:DGEO RS11975
gene id: 319795:DGEO_RS11975
uniprot id: Q1IX96
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

319795:DGEO RS05175
gene id: 319795:DGEO_RS05175
uniprot id: Q1J132
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

319795:DGEO RS14445
gene id: 319795:DGEO_RS14445
uniprot id: Q1IVW9
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

319795:DGEO RS09670
gene id: 319795:DGEO_RS09670
uniprot id: Q1IYJ5
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

319795:DGEO RS09965
gene id: 319795:DGEO_RS09965
uniprot id: Q1IYD8
names: Similarity
messages: Belongs to the threonine aldolase family.

319795:DGEO RS10555
gene id: 319795:DGEO_RS10555
uniprot id: Q1IY23
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

319795:DGEO RS06775
gene id: 319795:DGEO_RS06775
uniprot id: Q1J069
names: Subcellular Location Annotation
messages: Membrane

319795:DGEO RS10825
gene id: 319795:DGEO_RS10825
uniprot id: Q1IXX1
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

319795:DGEO RS14255
gene id: 319795:DGEO_RS14255
uniprot id: Q1IW06
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

319795:DGEO RS04405
gene id: 319795:DGEO_RS04405
uniprot id: Q1J1H8
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

319795:DGEO RS01940
gene id: 319795:DGEO_RS01940
uniprot id: Q1J390
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20 family.
messages: Binds 2 Zn(2+) ions per subunit.

319795:DGEO RS06180
gene id: 319795:DGEO_RS06180
uniprot id: Q1J0I8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

319795:DGEO RS04845
gene id: 319795:DGEO_RS04845
uniprot id: Q1J196
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

319795:DGEO RS04835
gene id: 319795:DGEO_RS04835
uniprot id: Q1J198
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

319795:DGEO RS07830
gene id: 319795:DGEO_RS07830
uniprot id: Q1IZL0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

319795:DGEO RS05835
gene id: 319795:DGEO_RS05835
uniprot id: Q1J0Q2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transcriptional regulatory Rex family.
messages: Cytoplasm
messages: Homodimer.
messages: Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.

319795:DGEO RS14280
gene id: 319795:DGEO_RS14280
uniprot id: Q1IW00
names: Similarity
messages: Belongs to the Nth/MutY family.

319795:DGEO RS10675
gene id: 319795:DGEO_RS10675
uniprot id: Q1IY01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

319795:DGEO RS02550
gene id: 319795:DGEO_RS02550
uniprot id: Q1J3L7
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

319795:DGEO RS01945
gene id: 319795:DGEO_RS01945
uniprot id: Q1J391
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Allantoinase family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Carboxylation allows a single lysine to coordinate two zinc ions.
messages: Catalyzes the conversion of allantoin (5-ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring.
messages: Homotetramer.

319795:DGEO RS13415
gene id: 319795:DGEO_RS13415
uniprot id: Q1IWG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

319795:DGEO RS05095
gene id: 319795:DGEO_RS05095
uniprot id: Q1J146
names: Subcellular Location Annotation
messages: Membrane

319795:DGEO RS13675
gene id: 319795:DGEO_RS13675
uniprot id: Q1IWB6
names: Function
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.
messages: Catalyzes the ATP-dependent phosphorylation of fructose-l-phosphate to fructose-l,6-bisphosphate.

319795:DGEO RS04050
gene id: 319795:DGEO_RS04050
uniprot id: Q1J1P4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

319795:DGEO RS12785
gene id: 319795:DGEO_RS12785
uniprot id: Q1IWU2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. MqnC family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2).

319795:DGEO RS05695
gene id: 319795:DGEO_RS05695
uniprot id: Q1J0S9
names: Similarity
messages: Belongs to the DEAD box helicase family. DDX21/DDX50 subfamily.

319795:DGEO RS01960
gene id: 319795:DGEO_RS01960
uniprot id: Q1J394
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia.

319795:DGEO RS08075
gene id: 319795:DGEO_RS08075
uniprot id: Q1IZF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

319795:DGEO RS07565
gene id: 319795:DGEO_RS07565
uniprot id: Q1IZR4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

319795:DGEO RS10570
gene id: 319795:DGEO_RS10570
uniprot id: Q1IY20
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.
messages: In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: In the N-terminal section; belongs to the MIP18 family.

319795:DGEO RS01690
gene id: 319795:DGEO_RS01690
uniprot id: Q1J338
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

319795:DGEO RS01340
gene id: 319795:DGEO_RS01340
uniprot id: Q1J2W6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urocanase family.
messages: Binds 1 NAD(+) per subunit.
messages: Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
messages: Cytoplasm

319795:DGEO RS11200
gene id: 319795:DGEO_RS11200
uniprot id: Q1IXP7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

319795:DGEO RS03630
gene id: 319795:DGEO_RS03630
uniprot id: Q1J1X6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

319795:DGEO RS00180
gene id: 319795:DGEO_RS00180
uniprot id: Q1J3Q7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family.
messages: Membrane

319795:DGEO RS02925
gene id: 319795:DGEO_RS02925
uniprot id: Q1J2B3
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

319795:DGEO RS06655
gene id: 319795:DGEO_RS06655
uniprot id: Q1J093
names: Subcellular Location Annotation
messages: Membrane

319795:DGEO RS05875
gene id: 319795:DGEO_RS05875
uniprot id: Q1J0P4
names: Subcellular Location Annotation
messages: Cytoplasm

319795:DGEO RS08410
gene id: 319795:DGEO_RS08410
uniprot id: Q1IZ92
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

319795:DGEO RS00890
gene id: 319795:DGEO_RS00890
uniprot id: Q1J2M5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

319795:DGEO RS03055
gene id: 319795:DGEO_RS03055
uniprot id: Q1J288
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

319795:DGEO RS02260
gene id: 319795:DGEO_RS02260
uniprot id: Q1J3F5
names: Similarity
messages: Belongs to the UPF0166 family.

319795:DGEO RS00670
gene id: 319795:DGEO_RS00670
uniprot id: Q1J2I2
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

319795:DGEO RS07010
gene id: 319795:DGEO_RS07010
uniprot id: Q1J021
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.

319795:DGEO RS00695
gene id: 319795:DGEO_RS00695
uniprot id: Q1J2I7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

319795:DGEO RS07280
gene id: 319795:DGEO_RS07280
uniprot id: Q1IZW8
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

319795:DGEO RS08555
gene id: 319795:DGEO_RS08555
uniprot id: Q1IZ63
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

319795:DGEO RS05720
gene id: 319795:DGEO_RS05720
uniprot id: Q1J0S4
names: Similarity
messages: Belongs to the Nudix hydrolase family.

319795:DGEO RS02945
gene id: 319795:DGEO_RS02945
uniprot id: Q1J2A9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Could methylate the ribose at the nucleotide 34 wobble position in tRNA.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

319795:DGEO RS14400
gene id: 319795:DGEO_RS14400
uniprot id: Q1IVX7
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

319795:DGEO RS08835
gene id: 319795:DGEO_RS08835
uniprot id: Q1IZ07
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

319795:DGEO RS14105
gene id: 319795:DGEO_RS14105
uniprot id: Q1IW35
names: Subcellular Location Annotation
messages: Membrane

319795:DGEO RS13490
gene id: 319795:DGEO_RS13490
uniprot id: Q1IWF2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

319795:DGEO RS02705
gene id: 319795:DGEO_RS02705
uniprot id: Q1J2F6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

319795:DGEO RS08455
gene id: 319795:DGEO_RS08455
uniprot id: Q1IZ83
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 2 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

319795:DGEO RS10930
gene id: 319795:DGEO_RS10930
uniprot id: Q1IXV1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

319795:DGEO RS13315
gene id: 319795:DGEO_RS13315
uniprot id: Q1IWI7
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

319795:DGEO RS04315
gene id: 319795:DGEO_RS04315
uniprot id: Q1J1J7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M32 family.
messages: Binds 1 zinc ion per subunit.
messages: Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues.

319795:DGEO RS07865
gene id: 319795:DGEO_RS07865
uniprot id: Q1IZK3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 2 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

319795:DGEO RS05235
gene id: 319795:DGEO_RS05235
uniprot id: Q1J119
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

319795:DGEO RS01360
gene id: 319795:DGEO_RS01360
uniprot id: Q1J2X0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. HutI family.
messages: Binds 1 zinc or iron ion per subunit.
messages: Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate. It is the third step in the universal histidine degradation pathway.
messages: Cytoplasm

319795:DGEO RS09575
gene id: 319795:DGEO_RS09575
uniprot id: Q1IYL3
names: Subcellular Location Annotation
messages: Membrane

319795:DGEO RS09275
gene id: 319795:DGEO_RS09275
uniprot id: Q1IYS0
names: Similarity
messages: Belongs to the ComB family.

319795:DGEO RS13640
gene id: 319795:DGEO_RS13640
uniprot id: Q1IWC3
names: Subcellular Location Annotation
messages: Membrane

319795:DGEO RS07260
gene id: 319795:DGEO_RS07260
uniprot id: Q1IZX2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 15 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

319795:DGEO RS07945
gene id: 319795:DGEO_RS07945
uniprot id: Q1IZI7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

319795:DGEO RS05140
gene id: 319795:DGEO_RS05140
uniprot id: Q1J138
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

319795:DGEO RS12160
gene id: 319795:DGEO_RS12160
uniprot id: Q1IX60
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

319795:DGEO RS07285
gene id: 319795:DGEO_RS07285
uniprot id: Q1IZW7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the complex I 75 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.