317577:DFI RS07140
gene id: 317577:DFI_RS07140
uniprot id: A0A221SVZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

317577:DFI RS07370
gene id: 317577:DFI_RS07370
uniprot id: A0A221SZQ8
names: Similarity
messages: Belongs to the peptidase S41A family.

317577:DFI RS06880
gene id: 317577:DFI_RS06880
uniprot id: A0A221SVU2
names: Similarity
messages: Belongs to the antibiotic N-acetyltransferase family.

317577:DFI RS00760
gene id: 317577:DFI_RS00760
uniprot id: A0A221SSW4
names: Function
names: Similarity
messages: Belongs to the V-ATPase E subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

317577:DFI RS16350
gene id: 317577:DFI_RS16350
uniprot id: A0A221T1G9
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

317577:DFI RS10560
gene id: 317577:DFI_RS10560
uniprot id: A0A221SXL9
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

317577:DFI RS01750
gene id: 317577:DFI_RS01750
uniprot id: A0A221STC7
names: Similarity
messages: Belongs to the universal stress protein A family.

317577:DFI RS01130
gene id: 317577:DFI_RS01130
uniprot id: A0A221ST37
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

317577:DFI RS13570
gene id: 317577:DFI_RS13570
uniprot id: A0A221T021
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

317577:DFI RS10165
gene id: 317577:DFI_RS10165
uniprot id: A0A221SXF8
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Periplasm

317577:DFI RS04250
gene id: 317577:DFI_RS04250
uniprot id: A0A221SUJ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

317577:DFI RS13800
gene id: 317577:DFI_RS13800
uniprot id: A0A221T084
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

317577:DFI RS10665
gene id: 317577:DFI_RS10665
uniprot id: A0A221SXR0
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

317577:DFI RS01480
gene id: 317577:DFI_RS01480
uniprot id: A0A221ST71
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

317577:DFI RS06740
gene id: 317577:DFI_RS06740
uniprot id: A0A221SVQ6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

317577:DFI RS09710
gene id: 317577:DFI_RS09710
uniprot id: A0A221SX98
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

317577:DFI RS09015
gene id: 317577:DFI_RS09015
uniprot id: A0A221SWV5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

317577:DFI RS03155
gene id: 317577:DFI_RS03155
uniprot id: A0A221SU41
names: Subcellular Location Annotation
messages: Membrane

317577:DFI RS07560
gene id: 317577:DFI_RS07560
uniprot id: A0A221SW94
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

317577:DFI RS01000
gene id: 317577:DFI_RS01000
uniprot id: A0A221ST13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

317577:DFI RS11385
gene id: 317577:DFI_RS11385
uniprot id: A0A221SY17
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

317577:DFI RS02875
gene id: 317577:DFI_RS02875
uniprot id: A0A221STZ2
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

317577:DFI RS04505
gene id: 317577:DFI_RS04505
uniprot id: A0A221SUP0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

317577:DFI RS05760
gene id: 317577:DFI_RS05760
uniprot id: A0A221SVD5
names: Function
names: Similarity
messages: Belongs to the TrhO family.
messages: Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.

317577:DFI RS10900
gene id: 317577:DFI_RS10900
uniprot id: A0A221SXS3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

317577:DFI RS01490
gene id: 317577:DFI_RS01490
uniprot id: A0A221ST88
names: Similarity
messages: Belongs to the peptidase C56 family.

317577:DFI RS10570
gene id: 317577:DFI_RS10570
uniprot id: A0A221SXL7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

317577:DFI RS01100
gene id: 317577:DFI_RS01100
uniprot id: A0A221ST35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

317577:DFI RS07895
gene id: 317577:DFI_RS07895
uniprot id: A0A221SWB5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

317577:DFI RS08795
gene id: 317577:DFI_RS08795
uniprot id: A0A221SWS4
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.

317577:DFI RS02590
gene id: 317577:DFI_RS02590
uniprot id: A0A221STR2
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

317577:DFI RS08865
gene id: 317577:DFI_RS08865
uniprot id: A0A221SWS8
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

317577:DFI RS18475
gene id: 317577:DFI_RS18475
uniprot id: A0A221T2S1
names: Similarity
messages: Belongs to the phD/YefM antitoxin family.

317577:DFI RS06370
gene id: 317577:DFI_RS06370
uniprot id: A0A221SVJ5
names: Similarity
messages: Belongs to the ycf81 family.

317577:DFI RS13630
gene id: 317577:DFI_RS13630
uniprot id: A0A221SZ52
names: Similarity
messages: Belongs to the ParB family.

317577:DFI RS07575
gene id: 317577:DFI_RS07575
uniprot id: A0A221SW54
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

317577:DFI RS00225
gene id: 317577:DFI_RS00225
uniprot id: A0A221SSM5
names: Similarity
messages: Belongs to the DNA polymerase type-C family. DnaE2 subfamily.

317577:DFI RS15885
gene id: 317577:DFI_RS15885
uniprot id: A0A221T168
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

317577:DFI RS03795
gene id: 317577:DFI_RS03795
uniprot id: A0A221SZF9
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

317577:DFI RS09725
gene id: 317577:DFI_RS09725
uniprot id: A0A221SX81
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

317577:DFI RS02775
gene id: 317577:DFI_RS02775
uniprot id: A0A221STX8
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

317577:DFI RS09530
gene id: 317577:DFI_RS09530
uniprot id: A0A221SX61
names: Similarity
messages: Belongs to the SCO1/2 family.

317577:DFI RS18575
gene id: 317577:DFI_RS18575
uniprot id: A0A221T2R3
names: Similarity
messages: Belongs to the ParB family.

317577:DFI RS08830
gene id: 317577:DFI_RS08830
uniprot id: A0A221SWR8
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

317577:DFI RS06600
gene id: 317577:DFI_RS06600
uniprot id: A0A221SVR0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

317577:DFI RS10725
gene id: 317577:DFI_RS10725
uniprot id: A0A221SXP3
names: Function
names: Similarity
messages: Belongs to the MqnA/MqnD family. MqnD subfamily.
messages: Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).

317577:DFI RS15915
gene id: 317577:DFI_RS15915
uniprot id: A0A221T171
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

317577:DFI RS04930
gene id: 317577:DFI_RS04930
uniprot id: A0A221SV03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Membrane

317577:DFI RS07300
gene id: 317577:DFI_RS07300
uniprot id: A0A221SW07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

317577:DFI RS16635
gene id: 317577:DFI_RS16635
uniprot id: A0A221T1P9
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

317577:DFI RS05710
gene id: 317577:DFI_RS05710
uniprot id: A0A221SZG0
names: Subcellular Location Annotation
messages: Membrane

317577:DFI RS00360
gene id: 317577:DFI_RS00360
uniprot id: A0A221SSP0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

317577:DFI RS01795
gene id: 317577:DFI_RS01795
uniprot id: A0A221STD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

317577:DFI RS04370
gene id: 317577:DFI_RS04370
uniprot id: A0A221SUM2
names: Subcellular Location Annotation
messages: Membrane

317577:DFI RS04855
gene id: 317577:DFI_RS04855
uniprot id: A0A221SUV7
names: Similarity
messages: Belongs to the peptidase S13 family.

317577:DFI RS14220
gene id: 317577:DFI_RS14220
uniprot id: A0A221T0C9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpA family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds the extracellular potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

317577:DFI RS18085
gene id: 317577:DFI_RS18085
uniprot id: A0A221T2L0
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

317577:DFI RS17855
gene id: 317577:DFI_RS17855
uniprot id: A0A221T2B1
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

317577:DFI RS07205
gene id: 317577:DFI_RS07205
uniprot id: A0A221SW06
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

317577:DFI RS11280
gene id: 317577:DFI_RS11280
uniprot id: A0A221SZX3
names: Similarity
messages: Belongs to the peptidase S1C family.

317577:DFI RS09040
gene id: 317577:DFI_RS09040
uniprot id: A0A221SX13
names: Subcellular Location Annotation
messages: Membrane

317577:DFI RS11780
gene id: 317577:DFI_RS11780
uniprot id: A0A221SY61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
messages: Cell inner membrane
messages: Membrane

317577:DFI RS06525
gene id: 317577:DFI_RS06525
uniprot id: A0A221SVP1
names: Similarity
messages: Belongs to the peptidase S8 family.

317577:DFI RS06610
gene id: 317577:DFI_RS06610
uniprot id: A0A221SVR8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
messages: Homodimer.

317577:DFI RS12805
gene id: 317577:DFI_RS12805
uniprot id: A0A221SYM5
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.

317577:DFI RS16500
gene id: 317577:DFI_RS16500
uniprot id: A0A221T1H3
names: Subcellular Location Annotation
messages: Membrane

317577:DFI RS11125
gene id: 317577:DFI_RS11125
uniprot id: A0A221SXV4
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

317577:DFI RS11905
gene id: 317577:DFI_RS11905
uniprot id: A0A221SYD0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

317577:DFI RS02620
gene id: 317577:DFI_RS02620
uniprot id: A0A221STT5
names: Subcellular Location Annotation
messages: Membrane

317577:DFI RS01375
gene id: 317577:DFI_RS01375
uniprot id: A0A221ST73
names: Function
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the 2'-O methylation of guanosine at position 18 in tRNA.

317577:DFI RS07830
gene id: 317577:DFI_RS07830
uniprot id: A0A221SW96
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

317577:DFI RS16175
gene id: 317577:DFI_RS16175
uniprot id: A0A221T1B7
names: Subcellular Location Annotation
messages: Membrane

317577:DFI RS00400
gene id: 317577:DFI_RS00400
uniprot id: A0A221SSP4
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

317577:DFI RS04555
gene id: 317577:DFI_RS04555
uniprot id: A0A221SUQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0382 family.
messages: Membrane

317577:DFI RS15005
gene id: 317577:DFI_RS15005
uniprot id: A0A221T0U0
names: Similarity
messages: Belongs to the cytochrome P450 family.

317577:DFI RS01385
gene id: 317577:DFI_RS01385
uniprot id: A0A221SZ55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

317577:DFI RS06465
gene id: 317577:DFI_RS06465
uniprot id: A0A221SVL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

317577:DFI RS00055
gene id: 317577:DFI_RS00055
uniprot id: A0A221SSJ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

317577:DFI RS05550
gene id: 317577:DFI_RS05550
uniprot id: A0A221SV72
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

317577:DFI RS11530
gene id: 317577:DFI_RS11530
uniprot id: A0A221SY46
names: Similarity
messages: Belongs to the NAPRTase family.

317577:DFI RS15425
gene id: 317577:DFI_RS15425
uniprot id: A0A221T0Z0
names: Similarity
messages: Belongs to the ParB family.

317577:DFI RS07005
gene id: 317577:DFI_RS07005
uniprot id: A0A221SVY4
names: Subcellular Location Annotation
messages: Membrane

317577:DFI RS08950
gene id: 317577:DFI_RS08950
uniprot id: A0A221SWU1
names: Similarity
messages: Belongs to the radical SAM superfamily. KamA family.

317577:DFI RS02200
gene id: 317577:DFI_RS02200
uniprot id: A0A221STL4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

317577:DFI RS04075
gene id: 317577:DFI_RS04075
uniprot id: A0A221SUK8
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

317577:DFI RS13045
gene id: 317577:DFI_RS13045
uniprot id: A0A221SYW3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

317577:DFI RS02665
gene id: 317577:DFI_RS02665
uniprot id: A0A221STV4
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

317577:DFI RS04035
gene id: 317577:DFI_RS04035
uniprot id: A0A221SUG5
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

317577:DFI RS02215
gene id: 317577:DFI_RS02215
uniprot id: A0A221STL6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

317577:DFI RS16225
gene id: 317577:DFI_RS16225
uniprot id: A0A221T1E0
names: Subcellular Location Annotation
messages: Membrane

317577:DFI RS01430
gene id: 317577:DFI_RS01430
uniprot id: A0A221ST75
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

317577:DFI RS00785
gene id: 317577:DFI_RS00785
uniprot id: A0A221SSX2
names: Function
names: Similarity
messages: Belongs to the V-ATPase D subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

317577:DFI RS13215
gene id: 317577:DFI_RS13215
uniprot id: A0A221SYV1
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

317577:DFI RS11265
gene id: 317577:DFI_RS11265
uniprot id: A0A221SXX4
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

317577:DFI RS00235
gene id: 317577:DFI_RS00235
uniprot id: A0A221SSL7
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.

317577:DFI RS00880
gene id: 317577:DFI_RS00880
uniprot id: A0A221SZ82
names: Similarity
messages: Belongs to the Dps family.

317577:DFI RS07930
gene id: 317577:DFI_RS07930
uniprot id: A0A221SZL7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

317577:DFI RS00215
gene id: 317577:DFI_RS00215
uniprot id: A0A221SSM0
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Homodimer.

317577:DFI RS01825
gene id: 317577:DFI_RS01825
uniprot id: A0A221STE0
names: Subcellular Location Annotation
messages: Membrane

317577:DFI RS04965
gene id: 317577:DFI_RS04965
uniprot id: A0A221SUX9
names: Similarity
messages: Belongs to the peptidase S58 family.

317577:DFI RS06200
gene id: 317577:DFI_RS06200
uniprot id: A0A221SVJ1
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

317577:DFI RS20595
gene id: 317577:DFI_RS20595
uniprot id: A0A221SYQ3
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Periplasm

317577:DFI RS17545
gene id: 317577:DFI_RS17545
uniprot id: A0A221T2A7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.

317577:DFI RS11300
gene id: 317577:DFI_RS11300
uniprot id: A0A221SXX6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

317577:DFI RS11060
gene id: 317577:DFI_RS11060
uniprot id: A0A221SXX5
names: Similarity
messages: Belongs to the XseB family.

317577:DFI RS01700
gene id: 317577:DFI_RS01700
uniprot id: A0A221STD3
names: Similarity
messages: Belongs to the DinB family.

317577:DFI RS05410
gene id: 317577:DFI_RS05410
uniprot id: A0A221SV53
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

317577:DFI RS09160
gene id: 317577:DFI_RS09160
uniprot id: A0A221SX31
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

317577:DFI RS13460
gene id: 317577:DFI_RS13460
uniprot id: A0A221SYY4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.

317577:DFI RS13340
gene id: 317577:DFI_RS13340
uniprot id: A0A221SYV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

317577:DFI RS14745
gene id: 317577:DFI_RS14745
uniprot id: A0A221T0Q4
names: Similarity
messages: Belongs to the DapA family.

317577:DFI RS04990
gene id: 317577:DFI_RS04990
uniprot id: A0A221SV12
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

317577:DFI RS08945
gene id: 317577:DFI_RS08945
uniprot id: A0A221SWV9
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

317577:DFI RS06515
gene id: 317577:DFI_RS06515
uniprot id: A0A221SVN0
names: Subcellular Location Annotation
messages: Membrane

317577:DFI RS14655
gene id: 317577:DFI_RS14655
uniprot id: A0A221T0J0
names: Similarity
messages: Belongs to the universal stress protein A family.

317577:DFI RS09715
gene id: 317577:DFI_RS09715
uniprot id: A0A221SX77
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

317577:DFI RS09950
gene id: 317577:DFI_RS09950
uniprot id: A0A221SXC3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

317577:DFI RS09415
gene id: 317577:DFI_RS09415
uniprot id: A0A221SX17
names: Subcellular Location Annotation
messages: Membrane

317577:DFI RS19165
gene id: 317577:DFI_RS19165
uniprot id: A0A221T375
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

317577:DFI RS03350
gene id: 317577:DFI_RS03350
uniprot id: A0A221SU57
names: Similarity
messages: Belongs to the TelA family.

317577:DFI RS09295
gene id: 317577:DFI_RS09295
uniprot id: A0A221SX07
names: Cofactor
messages: Binds 1 FAD per subunit.

317577:DFI RS10260
gene id: 317577:DFI_RS10260
uniprot id: A0A221SXJ4
names: Function
names: Similarity
messages: Belongs to the KptA/TPT1 family.
messages: Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP-ribose 1''-2''-cyclic phosphate (APPR>P). May function as an ADP-ribosylase.

317577:DFI RS13575
gene id: 317577:DFI_RS13575
uniprot id: A0A221T067
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

317577:DFI RS13015
gene id: 317577:DFI_RS13015
uniprot id: A0A221SYV2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the CobB/CobQ family.
messages: Involved in acetate metabolism.
messages: The N-terminal region seems to be important for proper quaternary structure. The C-terminal region contains the substrate-binding site.

317577:DFI RS04320
gene id: 317577:DFI_RS04320
uniprot id: A0A221SUN3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

317577:DFI RS11755
gene id: 317577:DFI_RS11755
uniprot id: A0A221SY83
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

317577:DFI RS08440
gene id: 317577:DFI_RS08440
uniprot id: A0A221SWN9
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

317577:DFI RS03965
gene id: 317577:DFI_RS03965
uniprot id: A0A221SUG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmC/CycZ/HelC family.
messages: Membrane

317577:DFI RS06555
gene id: 317577:DFI_RS06555
uniprot id: A0A221SVS5
names: Subcellular Location Annotation
messages: Membrane

317577:DFI RS02785
gene id: 317577:DFI_RS02785
uniprot id: A0A221STU2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

317577:DFI RS00460
gene id: 317577:DFI_RS00460
uniprot id: A0A221SSR1
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

317577:DFI RS03530
gene id: 317577:DFI_RS03530
uniprot id: A0A221SUA8
names: Caution
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

317577:DFI RS15080
gene id: 317577:DFI_RS15080
uniprot id: A0A221T0S5
names: Similarity
messages: Belongs to the leucine-binding protein family.

317577:DFI RS02100
gene id: 317577:DFI_RS02100
uniprot id: A0A221STJ1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphopentomutase family.
messages: Binds 1 or 2 manganese ions.
messages: Cytoplasm
messages: Phosphotransfer between the C1 and C5 carbon atoms of pentose.

317577:DFI RS15760
gene id: 317577:DFI_RS15760
uniprot id: A0A221T177
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

317577:DFI RS11070
gene id: 317577:DFI_RS11070
uniprot id: A0A221SXW2
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSP33 family.
messages: Cytoplasm
messages: Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.
messages: Under oxidizing conditions two disulfide bonds are formed involving the reactive cysteines. Under reducing conditions zinc is bound to the reactive cysteines and the protein is inactive.

317577:DFI RS10125
gene id: 317577:DFI_RS10125
uniprot id: A0A221SXJ6
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

317577:DFI RS04790
gene id: 317577:DFI_RS04790
uniprot id: A0A221SUU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

317577:DFI RS02085
gene id: 317577:DFI_RS02085
uniprot id: A0A221STH3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
messages: Cytoplasm

317577:DFI RS13120
gene id: 317577:DFI_RS13120
uniprot id: A0A221SYX2
names: Function
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

317577:DFI RS10065
gene id: 317577:DFI_RS10065
uniprot id: A0A221SXD6
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

317577:DFI RS19430
gene id: 317577:DFI_RS19430
uniprot id: A0A221T3B0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

317577:DFI RS13760
gene id: 317577:DFI_RS13760
uniprot id: A0A221T042
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

317577:DFI RS04650
gene id: 317577:DFI_RS04650
uniprot id: A0A221SUS3
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

317577:DFI RS04600
gene id: 317577:DFI_RS04600
uniprot id: A0A221SUQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CitM (TC 2.A.11) transporter family.
messages: Cell membrane
messages: Membrane

317577:DFI RS16665
gene id: 317577:DFI_RS16665
uniprot id: A0A221T1P5
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

317577:DFI RS08305
gene id: 317577:DFI_RS08305
uniprot id: A0A221SWK8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

317577:DFI RS01890
gene id: 317577:DFI_RS01890
uniprot id: A0A221STG4
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily.

317577:DFI RS00445
gene id: 317577:DFI_RS00445
uniprot id: A0A221SSP6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

317577:DFI RS05140
gene id: 317577:DFI_RS05140
uniprot id: A0A221SV01
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

317577:DFI RS13830
gene id: 317577:DFI_RS13830
uniprot id: A0A221T055
names: Similarity
messages: Belongs to the selenium-binding protein family.

317577:DFI RS16950
gene id: 317577:DFI_RS16950
uniprot id: A0A221T1X3
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

317577:DFI RS07135
gene id: 317577:DFI_RS07135
uniprot id: A0A221SW23
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

317577:DFI RS06390
gene id: 317577:DFI_RS06390
uniprot id: A0A221SVN2
names: Similarity
messages: Belongs to the PHP hydrolase family. HisK subfamily.

317577:DFI RS06725
gene id: 317577:DFI_RS06725
uniprot id: A0A221SZK4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M3B family.
messages: Binds 1 zinc ion.
messages: Has oligopeptidase activity and degrades a variety of small bioactive peptides.

317577:DFI RS12970
gene id: 317577:DFI_RS12970
uniprot id: A0A221SYR0
names: Function
names: Similarity
messages: Belongs to the MqnA/MqnD family. MqnA subfamily.
messages: Catalyzes the dehydration of chorismate into 3-[(1-carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).

317577:DFI RS06055
gene id: 317577:DFI_RS06055
uniprot id: A0A221SVG2
names: Subcellular Location Annotation
messages: Membrane

317577:DFI RS07795
gene id: 317577:DFI_RS07795
uniprot id: A0A221SW90
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

317577:DFI RS14175
gene id: 317577:DFI_RS14175
uniprot id: A0A221T0B2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

317577:DFI RS16530
gene id: 317577:DFI_RS16530
uniprot id: A0A221T1M3
names: Subcellular Location Annotation
messages: Periplasm

317577:DFI RS03125
gene id: 317577:DFI_RS03125
uniprot id: A0A221SU43
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

317577:DFI RS12020
gene id: 317577:DFI_RS12020
uniprot id: A0A221SY97
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

317577:DFI RS10490
gene id: 317577:DFI_RS10490
uniprot id: A0A221SXM9
names: Similarity
messages: Belongs to the DinB family.

317577:DFI RS10280
gene id: 317577:DFI_RS10280
uniprot id: A0A221SZS8
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

317577:DFI RS06270
gene id: 317577:DFI_RS06270
uniprot id: A0A221SVH4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

317577:DFI RS01005
gene id: 317577:DFI_RS01005
uniprot id: A0A221ST10
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

317577:DFI RS13670
gene id: 317577:DFI_RS13670
uniprot id: A0A221SZ07
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

317577:DFI RS07405
gene id: 317577:DFI_RS07405
uniprot id: A0A221SW35
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

317577:DFI RS06130
gene id: 317577:DFI_RS06130
uniprot id: A0A221SVF7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

317577:DFI RS08625
gene id: 317577:DFI_RS08625
uniprot id: A0A221SWN8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds the 23S rRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the 50S ribosomal subunit.

317577:DFI RS05355
gene id: 317577:DFI_RS05355
uniprot id: A0A221SV42
names: Cofactor
messages: Can also use Mn(2+) ion.

317577:DFI RS13115
gene id: 317577:DFI_RS13115
uniprot id: A0A221SYT6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 2 lipoyl cofactors covalently.
messages: Forms a 24-polypeptide structural core with octahedral symmetry.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

317577:DFI RS17660
gene id: 317577:DFI_RS17660
uniprot id: A0A221T2C2
names: Subcellular Location Annotation
messages: Membrane

317577:DFI RS05280
gene id: 317577:DFI_RS05280
uniprot id: A0A221SV20
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

317577:DFI RS11405
gene id: 317577:DFI_RS11405
uniprot id: A0A221SXZ6
names: Subcellular Location Annotation
messages: Membrane

317577:DFI RS07035
gene id: 317577:DFI_RS07035
uniprot id: A0A221SVW7
names: Similarity
messages: Belongs to the RimK family. LysX subfamily.

317577:DFI RS18600
gene id: 317577:DFI_RS18600
uniprot id: A0A221T2U0
names: Subcellular Location Annotation
messages: Membrane

317577:DFI RS05690
gene id: 317577:DFI_RS05690
uniprot id: A0A221SVC4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

317577:DFI RS01565
gene id: 317577:DFI_RS01565
uniprot id: A0A221STA9
names: Similarity
messages: Belongs to the creatininase superfamily.

317577:DFI RS00485
gene id: 317577:DFI_RS00485
uniprot id: A0A221SSQ9
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

317577:DFI RS06050
gene id: 317577:DFI_RS06050
uniprot id: A0A221SVI9
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

317577:DFI RS17505
gene id: 317577:DFI_RS17505
uniprot id: A0A221T258
names: Similarity
messages: Belongs to the polysaccharide synthase family.

317577:DFI RS12230
gene id: 317577:DFI_RS12230
uniprot id: A0A221SYC2
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

317577:DFI RS09630
gene id: 317577:DFI_RS09630
uniprot id: A0A221SXB3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

317577:DFI RS03390
gene id: 317577:DFI_RS03390
uniprot id: A0A221SU83
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

317577:DFI RS00945
gene id: 317577:DFI_RS00945
uniprot id: A0A221SSY8
names: Similarity
messages: Belongs to the UPF0102 family.

317577:DFI RS06645
gene id: 317577:DFI_RS06645
uniprot id: A0A221SVQ2
names: Similarity
messages: Belongs to the prephenate/arogenate dehydrogenase family.

317577:DFI RS04740
gene id: 317577:DFI_RS04740
uniprot id: A0A221SUT7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

317577:DFI RS02635
gene id: 317577:DFI_RS02635
uniprot id: A0A221STU9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

317577:DFI RS02355
gene id: 317577:DFI_RS02355
uniprot id: A0A221SZB9
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

317577:DFI RS10290
gene id: 317577:DFI_RS10290
uniprot id: A0A221SXH7
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

317577:DFI RS02010
gene id: 317577:DFI_RS02010
uniprot id: A0A221STG7
names: Subcellular Location Annotation
messages: Membrane

317577:DFI RS00765
gene id: 317577:DFI_RS00765
uniprot id: A0A221SSW7
names: Function
names: Similarity
messages: Belongs to the V-ATPase V0D/AC39 subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

317577:DFI RS02230
gene id: 317577:DFI_RS02230
uniprot id: A0A221STL3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

317577:DFI RS09175
gene id: 317577:DFI_RS09175
uniprot id: A0A221SWX8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

317577:DFI RS02625
gene id: 317577:DFI_RS02625
uniprot id: A0A221STR8
names: Subcellular Location Annotation
messages: Membrane

317577:DFI RS11505
gene id: 317577:DFI_RS11505
uniprot id: A0A221SY58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm

317577:DFI RS03875
gene id: 317577:DFI_RS03875
uniprot id: A0A221SUI1
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

317577:DFI RS13020
gene id: 317577:DFI_RS13020
uniprot id: A0A221SYU5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

317577:DFI RS05645
gene id: 317577:DFI_RS05645
uniprot id: A0A221SVA3
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

317577:DFI RS00150
gene id: 317577:DFI_RS00150
uniprot id: A0A221SSK8
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

317577:DFI RS16090
gene id: 317577:DFI_RS16090
uniprot id: A0A221T1A3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

317577:DFI RS08095
gene id: 317577:DFI_RS08095
uniprot id: A0A221SWD6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. MalFG subfamily.
messages: Cell membrane
messages: Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Probably responsible for the translocation of the substrate across the membrane.

317577:DFI RS16030
gene id: 317577:DFI_RS16030
uniprot id: A0A221T1D6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

317577:DFI RS09025
gene id: 317577:DFI_RS09025
uniprot id: A0A221SWW5
names: Similarity
messages: Belongs to the asp23 family.

317577:DFI RS00105
gene id: 317577:DFI_RS00105
uniprot id: A0A221SSK1
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

317577:DFI RS04625
gene id: 317577:DFI_RS04625
uniprot id: A0A221SUT6
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

317577:DFI RS02090
gene id: 317577:DFI_RS02090
uniprot id: A0A221SZ91
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

317577:DFI RS08050
gene id: 317577:DFI_RS08050
uniprot id: A0A221SWD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

317577:DFI RS11515
gene id: 317577:DFI_RS11515
uniprot id: A0A221SY10
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

317577:DFI RS17650
gene id: 317577:DFI_RS17650
uniprot id: A0A221T2A0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

317577:DFI RS13065
gene id: 317577:DFI_RS13065
uniprot id: A0A221SYW2
names: Cofactor
names: Similarity
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.

317577:DFI RS13415
gene id: 317577:DFI_RS13415
uniprot id: A0A221SYX6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

317577:DFI RS13640
gene id: 317577:DFI_RS13640
uniprot id: A0A221SZ14
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

317577:DFI RS04490
gene id: 317577:DFI_RS04490
uniprot id: A0A221SUN9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

317577:DFI RS08200
gene id: 317577:DFI_RS08200
uniprot id: A0A221SWG9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RNase HII family.
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

317577:DFI RS00900
gene id: 317577:DFI_RS00900
uniprot id: A0A221SSX6
names: Function
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 2 subfamily.
messages: Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 2-succinylbenzoate (OSB).

317577:DFI RS06065
gene id: 317577:DFI_RS06065
uniprot id: A0A221SVE6
names: Subcellular Location Annotation
messages: Membrane

317577:DFI RS06225
gene id: 317577:DFI_RS06225
uniprot id: A0A221SVK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

317577:DFI RS17655
gene id: 317577:DFI_RS17655
uniprot id: A0A221T2C5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

317577:DFI RS03080
gene id: 317577:DFI_RS03080
uniprot id: A0A221SU13
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

317577:DFI RS11700
gene id: 317577:DFI_RS11700
uniprot id: A0A221SY75
names: Subcellular Location Annotation
messages: Membrane

317577:DFI RS16235
gene id: 317577:DFI_RS16235
uniprot id: A0A221T1C9
names: Similarity
messages: Belongs to the FGGY kinase family.

317577:DFI RS19660
gene id: 317577:DFI_RS19660
uniprot id: A0A221T3D7
names: Similarity
messages: Belongs to the peptidase S8 family.

317577:DFI RS06765
gene id: 317577:DFI_RS06765
uniprot id: A0A221SVR4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

317577:DFI RS01610
gene id: 317577:DFI_RS01610
uniprot id: A0A221STB5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

317577:DFI RS04730
gene id: 317577:DFI_RS04730
uniprot id: A0A221SUT3
names: Subcellular Location Annotation
messages: Membrane

317577:DFI RS08405
gene id: 317577:DFI_RS08405
uniprot id: A0A221SWK2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. LysJ subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the transfer of the amino group of L-glutamate to [LysW]-aminoadipate 6-semialdehyde, generating [LysW]-gamma-L-lysine.
messages: Cytoplasm
messages: Homodimer.

317577:DFI RS00705
gene id: 317577:DFI_RS00705
uniprot id: A0A221SSV2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

317577:DFI RS08480
gene id: 317577:DFI_RS08480
uniprot id: A0A221SWL2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Cyclase 1 superfamily. KynB family.
messages: Binds 2 zinc ions per subunit.
messages: Catalyzes the hydrolysis of N-formyl-L-kynurenine to L-kynurenine, the second step in the kynurenine pathway of tryptophan degradation.
messages: Homodimer.

317577:DFI RS01925
gene id: 317577:DFI_RS01925
uniprot id: A0A221STF6
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

317577:DFI RS16470
gene id: 317577:DFI_RS16470
uniprot id: A0A221T1H4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NiCoT transporter (TC 2.A.52) family.
messages: Cell membrane
messages: Membrane

317577:DFI RS01635
gene id: 317577:DFI_RS01635
uniprot id: A0A221STA8
names: Similarity
messages: Belongs to the UPF0047 family.

317577:DFI RS02440
gene id: 317577:DFI_RS02440
uniprot id: A0A221STQ5
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

317577:DFI RS03150
gene id: 317577:DFI_RS03150
uniprot id: A0A221SU45
names: Similarity
messages: Belongs to the peptidase C40 family.

317577:DFI RS11715
gene id: 317577:DFI_RS11715
uniprot id: A0A221SY47
names: Similarity
messages: Belongs to the shaker potassium channel beta subunit family.

317577:DFI RS03240
gene id: 317577:DFI_RS03240
uniprot id: A0A221SU47
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

317577:DFI RS15970
gene id: 317577:DFI_RS15970
uniprot id: A0A221T196
names: Similarity
messages: Belongs to the OsmC/Ohr family.

317577:DFI RS08685
gene id: 317577:DFI_RS08685
uniprot id: A0A221SZV3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

317577:DFI RS17875
gene id: 317577:DFI_RS17875
uniprot id: A0A221T2F3
names: Similarity
messages: Belongs to the bacterial solute-binding protein 1 family.

317577:DFI RS07850
gene id: 317577:DFI_RS07850
uniprot id: A0A221SWE3
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

317577:DFI RS09035
gene id: 317577:DFI_RS09035
uniprot id: A0A221SWV4
names: Similarity
messages: Belongs to the BMP lipoprotein family.

317577:DFI RS08860
gene id: 317577:DFI_RS08860
uniprot id: A0A221SWT4
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

317577:DFI RS10265
gene id: 317577:DFI_RS10265
uniprot id: A0A221SXJ9
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 2 residues (Tyr-66 and Arg-69) present in a large hydrophobic pocket are probably involved in substrate specificity. They are important for desuccinylation activity, but dispensable for deacetylation activity.
messages: Belongs to the sirtuin family. Class III subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form.

317577:DFI RS15305
gene id: 317577:DFI_RS15305
uniprot id: A0A221T0Z9
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

317577:DFI RS07520
gene id: 317577:DFI_RS07520
uniprot id: A0A221SW40
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. LysZ subfamily.
messages: Catalyzes the phosphorylation of LysW-gamma-alpha-aminoadipate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

317577:DFI RS07550
gene id: 317577:DFI_RS07550
uniprot id: A0A221SW57
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

317577:DFI RS09125
gene id: 317577:DFI_RS09125
uniprot id: A0A221SWX2
names: Similarity
messages: Belongs to the OMP decarboxylase family. Type 2 subfamily.

317577:DFI RS09300
gene id: 317577:DFI_RS09300
uniprot id: A0A221SX38
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

317577:DFI RS02645
gene id: 317577:DFI_RS02645
uniprot id: A0A221STS8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

317577:DFI RS08220
gene id: 317577:DFI_RS08220
uniprot id: A0A221SWG1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

317577:DFI RS09975
gene id: 317577:DFI_RS09975
uniprot id: A0A221SXE1
names: Similarity
messages: Belongs to the glutamine synthetase family.

317577:DFI RS13775
gene id: 317577:DFI_RS13775
uniprot id: A0A221T086
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. TCR/Tet family.
messages: Membrane

317577:DFI RS04595
gene id: 317577:DFI_RS04595
uniprot id: A0A221SUR6
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

317577:DFI RS00495
gene id: 317577:DFI_RS00495
uniprot id: A0A221SSQ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

317577:DFI RS17900
gene id: 317577:DFI_RS17900
uniprot id: A0A221T2G7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NlpA lipoprotein family.
messages: Membrane

317577:DFI RS08525
gene id: 317577:DFI_RS08525
uniprot id: A0A221SWP2
names: Similarity
messages: Belongs to the RelA/SpoT family.

317577:DFI RS06310
gene id: 317577:DFI_RS06310
uniprot id: A0A221SVJ6
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

317577:DFI RS04820
gene id: 317577:DFI_RS04820
uniprot id: A0A221SUV0
names: Similarity
messages: Belongs to the AlaDH/PNT family.

317577:DFI RS01425
gene id: 317577:DFI_RS01425
uniprot id: A0A221ST82
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

317577:DFI RS07305
gene id: 317577:DFI_RS07305
uniprot id: A0A221SW37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

317577:DFI RS07400
gene id: 317577:DFI_RS07400
uniprot id: A0A221SW65
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

317577:DFI RS04260
gene id: 317577:DFI_RS04260
uniprot id: A0A221SUP1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

317577:DFI RS18605
gene id: 317577:DFI_RS18605
uniprot id: A0A221T2T8
names: Subcellular Location Annotation
messages: Membrane

317577:DFI RS11985
gene id: 317577:DFI_RS11985
uniprot id: A0A221SY94
names: Subcellular Location Annotation
messages: Membrane

317577:DFI RS02650
gene id: 317577:DFI_RS02650
uniprot id: A0A221STU7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

317577:DFI RS12010
gene id: 317577:DFI_RS12010
uniprot id: A0A221SYA2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the complex I 75 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

317577:DFI RS03865
gene id: 317577:DFI_RS03865
uniprot id: A0A221SUD3
names: Similarity
messages: Belongs to the GSP E family.

317577:DFI RS13710
gene id: 317577:DFI_RS13710
uniprot id: A0A221T029
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M32 family.
messages: Binds 1 zinc ion per subunit.
messages: Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues.

317577:DFI RS12145
gene id: 317577:DFI_RS12145
uniprot id: A0A221SYH0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

317577:DFI RS09190
gene id: 317577:DFI_RS09190
uniprot id: A0A221SX18
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

317577:DFI RS04385
gene id: 317577:DFI_RS04385
uniprot id: A0A221SUL9
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

317577:DFI RS04620
gene id: 317577:DFI_RS04620
uniprot id: A0A221SUR0
names: Similarity
messages: Belongs to the Fur family.

317577:DFI RS14910
gene id: 317577:DFI_RS14910
uniprot id: A0A221T0P6
names: Subcellular Location Annotation
messages: Membrane

317577:DFI RS12945
gene id: 317577:DFI_RS12945
uniprot id: A0A221SYQ0
names: Similarity
messages: Belongs to the peptidase S58 family.

317577:DFI RS16610
gene id: 317577:DFI_RS16610
uniprot id: A0A221T1N4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

317577:DFI RS03740
gene id: 317577:DFI_RS03740
uniprot id: A0A221SUB8
names: Function
names: Similarity
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

317577:DFI RS01980
gene id: 317577:DFI_RS01980
uniprot id: A0A221SZB0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxine kinase family. PdxY subfamily.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP.

317577:DFI RS12660
gene id: 317577:DFI_RS12660
uniprot id: A0A221SYP3
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

317577:DFI RS04585
gene id: 317577:DFI_RS04585
uniprot id: A0A221SUT5
names: Subcellular Location Annotation
messages: Membrane

317577:DFI RS09835
gene id: 317577:DFI_RS09835
uniprot id: A0A221SXA0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

317577:DFI RS04135
gene id: 317577:DFI_RS04135
uniprot id: A0A221SZB2
names: Similarity
messages: Belongs to the fabD family.

317577:DFI RS03160
gene id: 317577:DFI_RS03160
uniprot id: A0A221SU11
names: Subcellular Location Annotation
messages: Membrane

317577:DFI RS06520
gene id: 317577:DFI_RS06520
uniprot id: A0A221SVM8
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

317577:DFI RS14950
gene id: 317577:DFI_RS14950
uniprot id: A0A221T0S7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

317577:DFI RS12390
gene id: 317577:DFI_RS12390
uniprot id: A0A221SYF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Membrane

317577:DFI RS07485
gene id: 317577:DFI_RS07485
uniprot id: A0A221SW41
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

317577:DFI RS13265
gene id: 317577:DFI_RS13265
uniprot id: A0A221SYW8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
messages: Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
messages: Homodimer.

317577:DFI RS02670
gene id: 317577:DFI_RS02670
uniprot id: A0A221STU6
names: Similarity
messages: Belongs to the AHA1 family.

317577:DFI RS00660
gene id: 317577:DFI_RS00660
uniprot id: A0A221SST9
names: Similarity
messages: Belongs to the P(II) protein family.

317577:DFI RS06150
gene id: 317577:DFI_RS06150
uniprot id: A0A221SVF4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

317577:DFI RS06475
gene id: 317577:DFI_RS06475
uniprot id: A0A221SVN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

317577:DFI RS14180
gene id: 317577:DFI_RS14180
uniprot id: A0A221T0F5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

317577:DFI RS03905
gene id: 317577:DFI_RS03905
uniprot id: A0A221SUE5
names: Similarity
messages: Belongs to the Nudix hydrolase family.

317577:DFI RS17345
gene id: 317577:DFI_RS17345
uniprot id: A0A221T220
names: Subcellular Location Annotation
messages: Membrane

317577:DFI RS17690
gene id: 317577:DFI_RS17690
uniprot id: A0A221T296
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

317577:DFI RS17865
gene id: 317577:DFI_RS17865
uniprot id: A0A221T2P2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

317577:DFI RS12675
gene id: 317577:DFI_RS12675
uniprot id: A0A221SYK9
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

317577:DFI RS13565
gene id: 317577:DFI_RS13565
uniprot id: A0A221SZ04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XseA family.
messages: Cytoplasm

317577:DFI RS00830
gene id: 317577:DFI_RS00830
uniprot id: A0A221SSY0
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

317577:DFI RS06480
gene id: 317577:DFI_RS06480
uniprot id: A0A221SVL6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

317577:DFI RS10890
gene id: 317577:DFI_RS10890
uniprot id: A0A221SXS2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

317577:DFI RS13895
gene id: 317577:DFI_RS13895
uniprot id: A0A221T062
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

317577:DFI RS14490
gene id: 317577:DFI_RS14490
uniprot id: A0A221T0L3
names: Similarity
messages: Belongs to the peptidase M29 family.

317577:DFI RS17610
gene id: 317577:DFI_RS17610
uniprot id: A0A221T278
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A lyase-type mechanism (elimination/hydration) is suggested for the cleavage of the lactyl ether bond of MurNAc 6-phosphate, with the formation of an alpha,beta-unsaturated aldehyde intermediate with (E)-stereochemistry, followed by the syn addition of water to give product.
messages: Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
messages: Homodimer.
messages: Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate.

317577:DFI RS08785
gene id: 317577:DFI_RS08785
uniprot id: A0A221SWT0
names: Cofactor
messages: The heme is bound between the two transmembrane subunits.

317577:DFI RS07870
gene id: 317577:DFI_RS07870
uniprot id: A0A221SW99
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

317577:DFI RS07430
gene id: 317577:DFI_RS07430
uniprot id: A0A221SW33
names: Caution
names: Cofactor
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

317577:DFI RS02745
gene id: 317577:DFI_RS02745
uniprot id: A0A221STX3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

317577:DFI RS06070
gene id: 317577:DFI_RS06070
uniprot id: A0A221SZH5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

317577:DFI RS06785
gene id: 317577:DFI_RS06785
uniprot id: A0A221SVU0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PdxS/SNZ family.
messages: Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
messages: In the presence of PdxT, forms a dodecamer of heterodimers.

317577:DFI RS08110
gene id: 317577:DFI_RS08110
uniprot id: A0A221SWE9
names: Similarity
messages: Belongs to the PspA/IM30 family.

317577:DFI RS00780
gene id: 317577:DFI_RS00780
uniprot id: A0A221SSX1
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit.

317577:DFI RS09935
gene id: 317577:DFI_RS09935
uniprot id: A0A221SXD7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

317577:DFI RS02605
gene id: 317577:DFI_RS02605
uniprot id: A0A221STS9
names: Function
names: Similarity
messages: Belongs to the transglycosylase MltG family.
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

317577:DFI RS05010
gene id: 317577:DFI_RS05010
uniprot id: A0A221SUY1
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

317577:DFI RS14360
gene id: 317577:DFI_RS14360
uniprot id: A0A221T0H5
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

317577:DFI RS09955
gene id: 317577:DFI_RS09955
uniprot id: A0A221SXB9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-3 family.
messages: Cytoplasm
messages: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
messages: Monomer.

317577:DFI RS05880
gene id: 317577:DFI_RS05880
uniprot id: A0A221SVE2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

317577:DFI RS06810
gene id: 317577:DFI_RS06810
uniprot id: A0A221SVT9
names: Cofactor
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.

317577:DFI RS07215
gene id: 317577:DFI_RS07215
uniprot id: A0A221SVZ9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

317577:DFI RS15765
gene id: 317577:DFI_RS15765
uniprot id: A0A221T150
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

317577:DFI RS07480
gene id: 317577:DFI_RS07480
uniprot id: A0A221SW56
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

317577:DFI RS05150
gene id: 317577:DFI_RS05150
uniprot id: A0A221SV06
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

317577:DFI RS08545
gene id: 317577:DFI_RS08545
uniprot id: A0A221SWL5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

317577:DFI RS15750
gene id: 317577:DFI_RS15750
uniprot id: A0A221T154
names: Similarity
messages: Belongs to the universal stress protein A family.

317577:DFI RS13395
gene id: 317577:DFI_RS13395
uniprot id: A0A221T056
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

317577:DFI RS16660
gene id: 317577:DFI_RS16660
uniprot id: A0A221T1P4
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.

317577:DFI RS06460
gene id: 317577:DFI_RS06460
uniprot id: A0A221SVM0
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

317577:DFI RS11225
gene id: 317577:DFI_RS11225
uniprot id: A0A221SXX8
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

317577:DFI RS06325
gene id: 317577:DFI_RS06325
uniprot id: A0A221SVL4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
messages: Homodimer.

317577:DFI RS06040
gene id: 317577:DFI_RS06040
uniprot id: A0A221SVD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

317577:DFI RS07245
gene id: 317577:DFI_RS07245
uniprot id: A0A221SW27
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

317577:DFI RS15205
gene id: 317577:DFI_RS15205
uniprot id: A0A221T0V4
names: Subcellular Location Annotation
messages: Membrane

317577:DFI RS09250
gene id: 317577:DFI_RS09250
uniprot id: A0A221SWZ4
names: Similarity
messages: Belongs to the flavin oxidoreductase frp family.

317577:DFI RS09695
gene id: 317577:DFI_RS09695
uniprot id: A0A221SZX1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NucS endonuclease family.
messages: Cleaves both 3' and 5' ssDNA extremities of branched DNA structures.
messages: Cytoplasm

317577:DFI RS02765
gene id: 317577:DFI_RS02765
uniprot id: A0A221STW0
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

317577:DFI RS17740
gene id: 317577:DFI_RS17740
uniprot id: A0A221T299
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

317577:DFI RS04815
gene id: 317577:DFI_RS04815
uniprot id: A0A221SUY5
names: Function
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

317577:DFI RS00330
gene id: 317577:DFI_RS00330
uniprot id: A0A221SZ37
names: Similarity
messages: Belongs to the carotenoid/retinoid oxidoreductase family.

317577:DFI RS01850
gene id: 317577:DFI_RS01850
uniprot id: A0A221STF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

317577:DFI RS04225
gene id: 317577:DFI_RS04225
uniprot id: A0A221SUK7
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

317577:DFI RS01120
gene id: 317577:DFI_RS01120
uniprot id: A0A221ST29
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

317577:DFI RS17095
gene id: 317577:DFI_RS17095
uniprot id: A0A221T1X1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
messages: Cytoplasm

317577:DFI RS09730
gene id: 317577:DFI_RS09730
uniprot id: A0A221SX79
names: Function
names: Similarity
messages: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
messages: Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines.

317577:DFI RS18115
gene id: 317577:DFI_RS18115
uniprot id: A0A221T2K3
names: Subcellular Location Annotation
messages: Membrane

317577:DFI RS05480
gene id: 317577:DFI_RS05480
uniprot id: A0A221SV64
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

317577:DFI RS08535
gene id: 317577:DFI_RS08535
uniprot id: A0A221SWM3
names: Subcellular Location Annotation
messages: Membrane

317577:DFI RS07920
gene id: 317577:DFI_RS07920
uniprot id: A0A221SWC1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

317577:DFI RS05445
gene id: 317577:DFI_RS05445
uniprot id: A0A221SV77
names: Similarity
messages: Belongs to the acylphosphatase family.

317577:DFI RS05375
gene id: 317577:DFI_RS05375
uniprot id: A0A221SV68
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

317577:DFI RS06930
gene id: 317577:DFI_RS06930
uniprot id: A0A221SVU8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

317577:DFI RS06870
gene id: 317577:DFI_RS06870
uniprot id: A0A221SVV1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

317577:DFI RS12935
gene id: 317577:DFI_RS12935
uniprot id: A0A221SYP7
names: Similarity
messages: Belongs to the DinB family.

317577:DFI RS00665
gene id: 317577:DFI_RS00665
uniprot id: A0A221SST6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

317577:DFI RS02350
gene id: 317577:DFI_RS02350
uniprot id: A0A221STM0
names: Similarity
messages: Belongs to the UPF0111 family.

317577:DFI RS17580
gene id: 317577:DFI_RS17580
uniprot id: A0A221T2B0
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

317577:DFI RS04865
gene id: 317577:DFI_RS04865
uniprot id: A0A221SUV4
names: Similarity
messages: Belongs to the SufE family.

317577:DFI RS12830
gene id: 317577:DFI_RS12830
uniprot id: A0A221SYM4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

317577:DFI RS13540
gene id: 317577:DFI_RS13540
uniprot id: A0A221SYZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

317577:DFI RS09945
gene id: 317577:DFI_RS09945
uniprot id: A0A221SXD1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

317577:DFI RS02280
gene id: 317577:DFI_RS02280
uniprot id: A0A221STN7
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

317577:DFI RS06975
gene id: 317577:DFI_RS06975
uniprot id: A0A221SVW6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

317577:DFI RS07805
gene id: 317577:DFI_RS07805
uniprot id: A0A221SWA4
names: Similarity
messages: Belongs to the GARS family.

317577:DFI RS00015
gene id: 317577:DFI_RS00015
uniprot id: A0A221SSI2
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

317577:DFI RS00640
gene id: 317577:DFI_RS00640
uniprot id: A0A221SSU3
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

317577:DFI RS13230
gene id: 317577:DFI_RS13230
uniprot id: A0A221SYV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

317577:DFI RS17125
gene id: 317577:DFI_RS17125
uniprot id: A0A221T1Y7
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

317577:DFI RS06250
gene id: 317577:DFI_RS06250
uniprot id: A0A221SZM2
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruD family.
messages: Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.

317577:DFI RS09665
gene id: 317577:DFI_RS09665
uniprot id: A0A221SX83
names: Similarity
messages: Belongs to the phosphohexose mutase family.

317577:DFI RS09820
gene id: 317577:DFI_RS09820
uniprot id: A0A221SX96
names: Similarity
messages: Belongs to the peptidase M29 family.

317577:DFI RS07780
gene id: 317577:DFI_RS07780
uniprot id: A0A221SW91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

317577:DFI RS02885
gene id: 317577:DFI_RS02885
uniprot id: A0A221STY5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

317577:DFI RS06155
gene id: 317577:DFI_RS06155
uniprot id: A0A221SVI8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Forms a complex with TatA.
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.

317577:DFI RS09980
gene id: 317577:DFI_RS09980
uniprot id: A0A221SXC1
names: Similarity
messages: Belongs to the glutamine synthetase family.

317577:DFI RS07220
gene id: 317577:DFI_RS07220
uniprot id: A0A221SW04
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

317577:DFI RS03625
gene id: 317577:DFI_RS03625
uniprot id: A0A221SUB2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

317577:DFI RS01640
gene id: 317577:DFI_RS01640
uniprot id: A0A221STC3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

317577:DFI RS05095
gene id: 317577:DFI_RS05095
uniprot id: A0A221SZF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

317577:DFI RS09855
gene id: 317577:DFI_RS09855
uniprot id: A0A221SX97
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

317577:DFI RS17200
gene id: 317577:DFI_RS17200
uniprot id: A0A221T204
names: Subcellular Location Annotation
messages: Membrane

317577:DFI RS02530
gene id: 317577:DFI_RS02530
uniprot id: A0A221STS3
names: Similarity
messages: Belongs to the DEAD box helicase family.

317577:DFI RS01920
gene id: 317577:DFI_RS01920
uniprot id: A0A221STF8
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

317577:DFI RS02070
gene id: 317577:DFI_RS02070
uniprot id: A0A221STH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Membrane

317577:DFI RS11940
gene id: 317577:DFI_RS11940
uniprot id: A0A221SYB7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm

317577:DFI RS14160
gene id: 317577:DFI_RS14160
uniprot id: A0A221T097
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

317577:DFI RS03515
gene id: 317577:DFI_RS03515
uniprot id: A0A221SU99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

317577:DFI RS17375
gene id: 317577:DFI_RS17375
uniprot id: A0A221T223
names: Subcellular Location Annotation
messages: Membrane

317577:DFI RS00070
gene id: 317577:DFI_RS00070
uniprot id: A0A221SSJ7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

317577:DFI RS16945
gene id: 317577:DFI_RS16945
uniprot id: A0A221T1U6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

317577:DFI RS08040
gene id: 317577:DFI_RS08040
uniprot id: A0A221SWD0
names: Similarity
messages: Belongs to the peptidase S8 family.

317577:DFI RS10295
gene id: 317577:DFI_RS10295
uniprot id: A0A221SXM5
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

317577:DFI RS04120
gene id: 317577:DFI_RS04120
uniprot id: A0A221SUH8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

317577:DFI RS08275
gene id: 317577:DFI_RS08275
uniprot id: A0A221SZN0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

317577:DFI RS13735
gene id: 317577:DFI_RS13735
uniprot id: A0A221T019
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

317577:DFI RS02300
gene id: 317577:DFI_RS02300
uniprot id: A0A221STN5
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

317577:DFI RS04155
gene id: 317577:DFI_RS04155
uniprot id: A0A221SUL6
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

317577:DFI RS12025
gene id: 317577:DFI_RS12025
uniprot id: A0A221SZZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 15 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

317577:DFI RS09360
gene id: 317577:DFI_RS09360
uniprot id: A0A221SX22
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transcriptional regulatory Rex family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.

317577:DFI RS06985
gene id: 317577:DFI_RS06985
uniprot id: A0A221SVV6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.

317577:DFI RS04205
gene id: 317577:DFI_RS04205
uniprot id: A0A221SUL5
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

317577:DFI RS05965
gene id: 317577:DFI_RS05965
uniprot id: A0A221SVE0
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

317577:DFI RS13330
gene id: 317577:DFI_RS13330
uniprot id: A0A221SZ13
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

317577:DFI RS12135
gene id: 317577:DFI_RS12135
uniprot id: A0A221SYC1
names: Similarity
messages: Belongs to the CutA family.

317577:DFI RS01080
gene id: 317577:DFI_RS01080
uniprot id: A0A221ST23
names: Subcellular Location Annotation
messages: Membrane

317577:DFI RS16755
gene id: 317577:DFI_RS16755
uniprot id: A0A221T1S4
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

317577:DFI RS12975
gene id: 317577:DFI_RS12975
uniprot id: A0A221SYQ8
names: Similarity
messages: Belongs to the peptidase M16 family.

317577:DFI RS00825
gene id: 317577:DFI_RS00825
uniprot id: A0A221SSW8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

317577:DFI RS02205
gene id: 317577:DFI_RS02205
uniprot id: A0A221STJ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

317577:DFI RS18125
gene id: 317577:DFI_RS18125
uniprot id: A0A221T2G4
names: Subcellular Location Annotation
messages: Membrane

317577:DFI RS05855
gene id: 317577:DFI_RS05855
uniprot id: A0A221SVA7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. MqnC family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2).

317577:DFI RS14755
gene id: 317577:DFI_RS14755
uniprot id: A0A221T0L9
names: Subcellular Location Annotation
messages: Membrane

317577:DFI RS09485
gene id: 317577:DFI_RS09485
uniprot id: A0A221SX43
names: Similarity
messages: Belongs to the ComB family.

317577:DFI RS02965
gene id: 317577:DFI_RS02965
uniprot id: A0A221STX5
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

317577:DFI RS05485
gene id: 317577:DFI_RS05485
uniprot id: A0A221SV73
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

317577:DFI RS07510
gene id: 317577:DFI_RS07510
uniprot id: A0A221SW52
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

317577:DFI RS08065
gene id: 317577:DFI_RS08065
uniprot id: A0A221SWD9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

317577:DFI RS05405
gene id: 317577:DFI_RS05405
uniprot id: A0A221SV35
names: Subcellular Location Annotation
messages: Cytoplasm

317577:DFI RS12960
gene id: 317577:DFI_RS12960
uniprot id: A0A221SYU2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. MqnE family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3-[(1-carboxyvinyl)oxy]benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate.

317577:DFI RS11900
gene id: 317577:DFI_RS11900
uniprot id: A0A221SY77
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

317577:DFI RS17205
gene id: 317577:DFI_RS17205
uniprot id: A0A221T231
names: Subcellular Location Annotation
messages: Membrane

317577:DFI RS12925
gene id: 317577:DFI_RS12925
uniprot id: A0A221SYR2
names: Similarity
messages: Belongs to the DinB family.

317577:DFI RS02185
gene id: 317577:DFI_RS02185
uniprot id: A0A221STJ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

317577:DFI RS13040
gene id: 317577:DFI_RS13040
uniprot id: A0A221SYS2
names: Subcellular Location Annotation
messages: Membrane

317577:DFI RS12075
gene id: 317577:DFI_RS12075
uniprot id: A0A221SYB0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

317577:DFI RS11440
gene id: 317577:DFI_RS11440
uniprot id: A0A221SZW8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RuvC family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.

317577:DFI RS02950
gene id: 317577:DFI_RS02950
uniprot id: A0A221SU09
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

317577:DFI RS02245
gene id: 317577:DFI_RS02245
uniprot id: A0A221STM5
names: Similarity
messages: Belongs to the cytochrome c-552 family.

317577:DFI RS18020
gene id: 317577:DFI_RS18020
uniprot id: A0A221T2E9
names: Similarity
messages: Belongs to the PstS family.

317577:DFI RS09535
gene id: 317577:DFI_RS09535
uniprot id: A0A221SX37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane

317577:DFI RS11895
gene id: 317577:DFI_RS11895
uniprot id: A0A221SY76
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

317577:DFI RS04215
gene id: 317577:DFI_RS04215
uniprot id: A0A221SUK3
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

317577:DFI RS00280
gene id: 317577:DFI_RS00280
uniprot id: A0A221SSM8
names: Subcellular Location Annotation
messages: Membrane

317577:DFI RS14505
gene id: 317577:DFI_RS14505
uniprot id: A0A221T0I9
names: Subcellular Location Annotation
messages: Membrane

317577:DFI RS09765
gene id: 317577:DFI_RS09765
uniprot id: A0A221SX89
names: Similarity
messages: Belongs to the Nudix hydrolase family.

317577:DFI RS02305
gene id: 317577:DFI_RS02305
uniprot id: A0A221STN0
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

317577:DFI RS12265
gene id: 317577:DFI_RS12265
uniprot id: A0A221SYD3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

317577:DFI RS07675
gene id: 317577:DFI_RS07675
uniprot id: A0A221SW72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

317577:DFI RS17485
gene id: 317577:DFI_RS17485
uniprot id: A0A221T244
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

317577:DFI RS07375
gene id: 317577:DFI_RS07375
uniprot id: A0A221SZP6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division.

317577:DFI RS02455
gene id: 317577:DFI_RS02455
uniprot id: A0A221STQ2
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

317577:DFI RS18120
gene id: 317577:DFI_RS18120
uniprot id: A0A221T2G5
names: Subcellular Location Annotation
messages: Membrane

317577:DFI RS08465
gene id: 317577:DFI_RS08465
uniprot id: A0A221SWN4
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA.

317577:DFI RS11760
gene id: 317577:DFI_RS11760
uniprot id: A0A221SY55
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

317577:DFI RS07940
gene id: 317577:DFI_RS07940
uniprot id: A0A221SWC2
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

317577:DFI RS17905
gene id: 317577:DFI_RS17905
uniprot id: A0A221T2C9
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

317577:DFI RS17665
gene id: 317577:DFI_RS17665
uniprot id: A0A221T288
names: Subcellular Location Annotation
messages: Membrane

317577:DFI RS00610
gene id: 317577:DFI_RS00610
uniprot id: A0A221SST1
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.

317577:DFI RS08620
gene id: 317577:DFI_RS08620
uniprot id: A0A221SWQ7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.

317577:DFI RS03025
gene id: 317577:DFI_RS03025
uniprot id: A0A221SU05
names: Similarity
messages: Belongs to the citrate synthase family.

317577:DFI RS15975
gene id: 317577:DFI_RS15975
uniprot id: A0A221T188
names: Similarity
messages: Belongs to the leucine-binding protein family.

317577:DFI RS03380
gene id: 317577:DFI_RS03380
uniprot id: A0A221SU80
names: Subcellular Location Annotation
messages: Membrane

317577:DFI RS05145
gene id: 317577:DFI_RS05145
uniprot id: A0A221SUZ9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

317577:DFI RS07885
gene id: 317577:DFI_RS07885
uniprot id: A0A221SWA6
names: Similarity
messages: Belongs to the BshC family.

317577:DFI RS16135
gene id: 317577:DFI_RS16135
uniprot id: A0A221T1F6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM175 family.
messages: Membrane

317577:DFI RS03420
gene id: 317577:DFI_RS03420
uniprot id: A0A221SU48
names: Function
names: Similarity
messages: Belongs to the uroporphyrinogen-III synthase family.
messages: Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.

317577:DFI RS12335
gene id: 317577:DFI_RS12335
uniprot id: A0A221SYF1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

317577:DFI RS08260
gene id: 317577:DFI_RS08260
uniprot id: A0A221SWG5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

317577:DFI RS13280
gene id: 317577:DFI_RS13280
uniprot id: A0A221SYW0
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

317577:DFI RS10820
gene id: 317577:DFI_RS10820
uniprot id: A0A221SXQ8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Lacks the C-terminal regulatory region which is replaced by HisZ.

317577:DFI RS01510
gene id: 317577:DFI_RS01510
uniprot id: A0A221ST87
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

317577:DFI RS02905
gene id: 317577:DFI_RS02905
uniprot id: A0A221STY4
names: Similarity
messages: Belongs to the GSP E family.

317577:DFI RS15260
gene id: 317577:DFI_RS15260
uniprot id: A0A221T0W3
names: Subcellular Location Annotation
messages: Membrane

317577:DFI RS02770
gene id: 317577:DFI_RS02770
uniprot id: A0A221STW1
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

317577:DFI RS02805
gene id: 317577:DFI_RS02805
uniprot id: A0A221STV2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein L14 (rplN).

317577:DFI RS05350
gene id: 317577:DFI_RS05350
uniprot id: A0A221SV25
names: Similarity
messages: Belongs to the malate synthase family.

317577:DFI RS05380
gene id: 317577:DFI_RS05380
uniprot id: A0A221SV48
names: Subcellular Location Annotation
messages: Membrane

317577:DFI RS01860
gene id: 317577:DFI_RS01860
uniprot id: A0A221STF5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

317577:DFI RS04295
gene id: 317577:DFI_RS04295
uniprot id: A0A221SZG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Membrane

317577:DFI RS01505
gene id: 317577:DFI_RS01505
uniprot id: A0A221STA2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

317577:DFI RS14325
gene id: 317577:DFI_RS14325
uniprot id: A0A221T0E7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Set transporter family.
messages: Membrane

317577:DFI RS02335
gene id: 317577:DFI_RS02335
uniprot id: A0A221STN9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

317577:DFI RS09895
gene id: 317577:DFI_RS09895
uniprot id: A0A221SXA9
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

317577:DFI RS13225
gene id: 317577:DFI_RS13225
uniprot id: A0A221T011
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

317577:DFI RS06485
gene id: 317577:DFI_RS06485
uniprot id: A0A221SVP7
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

317577:DFI RS12580
gene id: 317577:DFI_RS12580
uniprot id: A0A221SYI7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pseudouridine-5'-phosphate glycosidase family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the reversible cleavage of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway.
messages: Homotrimer.

317577:DFI RS04080
gene id: 317577:DFI_RS04080
uniprot id: A0A221SUJ0
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

317577:DFI RS06550
gene id: 317577:DFI_RS06550
uniprot id: A0A221SVQ7
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

317577:DFI RS06710
gene id: 317577:DFI_RS06710
uniprot id: A0A221SVR1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

317577:DFI RS07090
gene id: 317577:DFI_RS07090
uniprot id: A0A221SVZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

317577:DFI RS01955
gene id: 317577:DFI_RS01955
uniprot id: A0A221STE8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

317577:DFI RS06925
gene id: 317577:DFI_RS06925
uniprot id: A0A221SVW2
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

317577:DFI RS11740
gene id: 317577:DFI_RS11740
uniprot id: A0A221SY53
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

317577:DFI RS02015
gene id: 317577:DFI_RS02015
uniprot id: A0A221STI4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

317577:DFI RS17170
gene id: 317577:DFI_RS17170
uniprot id: A0A221T214
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

317577:DFI RS16925
gene id: 317577:DFI_RS16925
uniprot id: A0A221T1U8
names: Similarity
messages: Belongs to the WrbA family.

317577:DFI RS04805
gene id: 317577:DFI_RS04805
uniprot id: A0A221SUU5
names: Function
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.

317577:DFI RS00490
gene id: 317577:DFI_RS00490
uniprot id: A0A221SSR3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

317577:DFI RS09285
gene id: 317577:DFI_RS09285
uniprot id: A0A221SX21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Membrane

317577:DFI RS03395
gene id: 317577:DFI_RS03395
uniprot id: A0A221SU66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

317577:DFI RS00920
gene id: 317577:DFI_RS00920
uniprot id: A0A221SSY9
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

317577:DFI RS06745
gene id: 317577:DFI_RS06745
uniprot id: A0A221SVT7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

317577:DFI RS00685
gene id: 317577:DFI_RS00685
uniprot id: A0A221SST8
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

317577:DFI RS09145
gene id: 317577:DFI_RS09145
uniprot id: A0A221SWY7
names: Similarity
messages: Belongs to the universal stress protein A family.

317577:DFI RS03355
gene id: 317577:DFI_RS03355
uniprot id: A0A221SU84
names: Subcellular Location Annotation
messages: Membrane

317577:DFI RS02170
gene id: 317577:DFI_RS02170
uniprot id: A0A221STK6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

317577:DFI RS08920
gene id: 317577:DFI_RS08920
uniprot id: A0A221SWU3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. HutI family.
messages: Binds 1 zinc or iron ion per subunit.
messages: Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate. It is the third step in the universal histidine degradation pathway.
messages: Cytoplasm

317577:DFI RS03690
gene id: 317577:DFI_RS03690
uniprot id: A0A221SUB7
names: Similarity
messages: Belongs to the ClpA/ClpB family.

317577:DFI RS07685
gene id: 317577:DFI_RS07685
uniprot id: A0A221SW69
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

317577:DFI RS19385
gene id: 317577:DFI_RS19385
uniprot id: A0A221T3N9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

317577:DFI RS03665
gene id: 317577:DFI_RS03665
uniprot id: A0A221SUD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsbB family. BdbC subfamily.
messages: Membrane

317577:DFI RS06865
gene id: 317577:DFI_RS06865
uniprot id: A0A221SVU9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

317577:DFI RS13130
gene id: 317577:DFI_RS13130
uniprot id: A0A221SYT8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

317577:DFI RS17300
gene id: 317577:DFI_RS17300
uniprot id: A0A221T224
names: Subcellular Location Annotation
messages: Membrane

317577:DFI RS08985
gene id: 317577:DFI_RS08985
uniprot id: A0A221SWZ8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

317577:DFI RS08450
gene id: 317577:DFI_RS08450
uniprot id: A0A221SWL7
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

317577:DFI RS08705
gene id: 317577:DFI_RS08705
uniprot id: A0A221SWQ1
names: Subcellular Location Annotation
messages: Membrane

317577:DFI RS04660
gene id: 317577:DFI_RS04660
uniprot id: A0A221SUR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

317577:DFI RS06840
gene id: 317577:DFI_RS06840
uniprot id: A0A221SVT4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell membrane
messages: Membrane

317577:DFI RS10625
gene id: 317577:DFI_RS10625
uniprot id: A0A221SXM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

317577:DFI RS12005
gene id: 317577:DFI_RS12005
uniprot id: A0A221SYA1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 15 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

317577:DFI RS10130
gene id: 317577:DFI_RS10130
uniprot id: A0A221SXE4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

317577:DFI RS07455
gene id: 317577:DFI_RS07455
uniprot id: A0A221SW50
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

317577:DFI RS02320
gene id: 317577:DFI_RS02320
uniprot id: A0A221STN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

317577:DFI RS03800
gene id: 317577:DFI_RS03800
uniprot id: A0A221SUC2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

317577:DFI RS05850
gene id: 317577:DFI_RS05850
uniprot id: A0A221SZM1
names: Similarity
messages: Belongs to the 6-phosphogluconate dehydrogenase family.

317577:DFI RS01560
gene id: 317577:DFI_RS01560
uniprot id: A0A221SZ48
names: Similarity
messages: Belongs to the ComB family.

317577:DFI RS10035
gene id: 317577:DFI_RS10035
uniprot id: A0A221SXC8
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

317577:DFI RS00970
gene id: 317577:DFI_RS00970
uniprot id: A0A221ST01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TspO/BZRP family.
messages: Membrane

317577:DFI RS02545
gene id: 317577:DFI_RS02545
uniprot id: A0A221STS4
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

317577:DFI RS06560
gene id: 317577:DFI_RS06560
uniprot id: A0A221SVP6
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

317577:DFI RS07595
gene id: 317577:DFI_RS07595
uniprot id: A0A221SW74
names: Similarity
messages: Belongs to the barstar family.

317577:DFI RS17800
gene id: 317577:DFI_RS17800
uniprot id: A0A221T2E4
names: Subcellular Location Annotation
messages: Membrane

317577:DFI RS12255
gene id: 317577:DFI_RS12255
uniprot id: A0A221SYE5
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

317577:DFI RS01350
gene id: 317577:DFI_RS01350
uniprot id: A0A221ST74
names: Function
names: Similarity
messages: Belongs to the BPG-independent phosphoglycerate mutase family. A-PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

317577:DFI RS06660
gene id: 317577:DFI_RS06660
uniprot id: A0A221SVS0
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

317577:DFI RS15065
gene id: 317577:DFI_RS15065
uniprot id: A0A221T0S6
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

317577:DFI RS02055
gene id: 317577:DFI_RS02055
uniprot id: A0A221STI9
names: Domain
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the CobB/CbiA family.
messages: Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source.
messages: Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP and cobyrinate and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.
messages: The a and c carboxylates of cobyrinate are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CbiA catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate.

317577:DFI RS06770
gene id: 317577:DFI_RS06770
uniprot id: A0A221SVS1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 3B subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

317577:DFI RS11830
gene id: 317577:DFI_RS11830
uniprot id: A0A221SZY4
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

317577:DFI RS02435
gene id: 317577:DFI_RS02435
uniprot id: A0A221STQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

317577:DFI RS10605
gene id: 317577:DFI_RS10605
uniprot id: A0A221SXQ0
names: Similarity
messages: Belongs to the AHA1 family.

317577:DFI RS02220
gene id: 317577:DFI_RS02220
uniprot id: A0A221STL1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

317577:DFI RS14970
gene id: 317577:DFI_RS14970
uniprot id: A0A221T0R1
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

317577:DFI RS11120
gene id: 317577:DFI_RS11120
uniprot id: A0A221SXV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0073 (Hly-III) family.
messages: Membrane

317577:DFI RS12015
gene id: 317577:DFI_RS12015
uniprot id: A0A221SYA0
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

317577:DFI RS16710
gene id: 317577:DFI_RS16710
uniprot id: A0A221T1Q4
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

317577:DFI RS14465
gene id: 317577:DFI_RS14465
uniprot id: A0A221T0J8
names: Similarity
messages: Belongs to the ketopantoate reductase family.

317577:DFI RS00840
gene id: 317577:DFI_RS00840
uniprot id: A0A221SSW6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

317577:DFI RS01935
gene id: 317577:DFI_RS01935
uniprot id: A0A221STH6
names: Subcellular Location Annotation
messages: Membrane

317577:DFI RS09605
gene id: 317577:DFI_RS09605
uniprot id: A0A221SX57
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

317577:DFI RS13245
gene id: 317577:DFI_RS13245
uniprot id: A0A221SYV9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

317577:DFI RS05660
gene id: 317577:DFI_RS05660
uniprot id: A0A221SV79
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

317577:DFI RS03940
gene id: 317577:DFI_RS03940
uniprot id: A0A221SUH4
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

317577:DFI RS11730
gene id: 317577:DFI_RS11730
uniprot id: A0A221SY44
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

317577:DFI RS12220
gene id: 317577:DFI_RS12220
uniprot id: A0A221SYH9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

317577:DFI RS00045
gene id: 317577:DFI_RS00045
uniprot id: A0A221SSJ3
names: Function
names: Similarity
messages: Belongs to the RNase Y family.
messages: Endoribonuclease that initiates mRNA decay.

317577:DFI RS06835
gene id: 317577:DFI_RS06835
uniprot id: A0A221SVT2
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

317577:DFI RS02910
gene id: 317577:DFI_RS02910
uniprot id: A0A221STV9
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

317577:DFI RS16615
gene id: 317577:DFI_RS16615
uniprot id: A0A221T1N8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

317577:DFI RS11065
gene id: 317577:DFI_RS11065
uniprot id: A0A221SXU5
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

317577:DFI RS06375
gene id: 317577:DFI_RS06375
uniprot id: A0A221SVM4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

317577:DFI RS07950
gene id: 317577:DFI_RS07950
uniprot id: A0A221SWB7
names: Similarity
messages: Belongs to the peptidase S8 family.

317577:DFI RS10860
gene id: 317577:DFI_RS10860
uniprot id: A0A221SXR9
names: Similarity
messages: Belongs to the peptidase S49 family.

317577:DFI RS11990
gene id: 317577:DFI_RS11990
uniprot id: A0A221SYC5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 15 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

317577:DFI RS02175
gene id: 317577:DFI_RS02175
uniprot id: A0A221STK8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

317577:DFI RS13150
gene id: 317577:DFI_RS13150
uniprot id: A0A221SYY5
names: Similarity
messages: Belongs to the universal stress protein A family.

317577:DFI RS08100
gene id: 317577:DFI_RS08100
uniprot id: A0A221SWI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

317577:DFI RS08360
gene id: 317577:DFI_RS08360
uniprot id: A0A221SWI9
names: Similarity
messages: Belongs to the DEAD box helicase family. DDX21/DDX50 subfamily.

317577:DFI RS09940
gene id: 317577:DFI_RS09940
uniprot id: A0A221SXB8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Monomer.

317577:DFI RS08500
gene id: 317577:DFI_RS08500
uniprot id: A0A221SWQ0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

317577:DFI RS17745
gene id: 317577:DFI_RS17745
uniprot id: A0A221T2A6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

317577:DFI RS02180
gene id: 317577:DFI_RS02180
uniprot id: A0A221STJ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

317577:DFI RS09575
gene id: 317577:DFI_RS09575
uniprot id: A0A221SXA3
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.

317577:DFI RS09345
gene id: 317577:DFI_RS09345
uniprot id: A0A221SX27
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

317577:DFI RS09970
gene id: 317577:DFI_RS09970
uniprot id: A0A221SZX2
names: Similarity
messages: Belongs to the antibiotic N-acetyltransferase family.

317577:DFI RS01695
gene id: 317577:DFI_RS01695
uniprot id: A0A221STC1
names: Cofactor
names: Similarity
messages: Belongs to the arginase family.
messages: Binds 2 manganese ions per subunit.

317577:DFI RS02050
gene id: 317577:DFI_RS02050
uniprot id: A0A221STI6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Membrane

317577:DFI RS09385
gene id: 317577:DFI_RS09385
uniprot id: A0A221SX15
names: Cofactor
names: Function
messages: Binds 2 [4Fe-4S] clusters.
messages: Component of a complex that catalyzes the oxidation of glycolate to glyoxylate.

317577:DFI RS03675
gene id: 317577:DFI_RS03675
uniprot id: A0A221SZA7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the zinc-containing alcohol dehydrogenase family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate.
messages: Cytoplasm
messages: Homotetramer.

317577:DFI RS08715
gene id: 317577:DFI_RS08715
uniprot id: A0A221SWP6
names: Subcellular Location Annotation
messages: Membrane

317577:DFI RS06415
gene id: 317577:DFI_RS06415
uniprot id: A0A221SVL9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 2 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

317577:DFI RS02160
gene id: 317577:DFI_RS02160
uniprot id: A0A221STK0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

317577:DFI RS06470
gene id: 317577:DFI_RS06470
uniprot id: A0A221SVM9
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

317577:DFI RS09155
gene id: 317577:DFI_RS09155
uniprot id: A0A221SWX3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PEPCase type 1 family.
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
messages: Homotetramer.

317577:DFI RS06495
gene id: 317577:DFI_RS06495
uniprot id: A0A221SVN8
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

317577:DFI RS17100
gene id: 317577:DFI_RS17100
uniprot id: A0A221T2N8
names: Similarity
messages: Belongs to the sulfate adenylyltransferase family.

317577:DFI RS06490
gene id: 317577:DFI_RS06490
uniprot id: A0A221SVR6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

317577:DFI RS08925
gene id: 317577:DFI_RS08925
uniprot id: A0A221SWT7
names: Similarity
messages: Belongs to the arginase family.

317577:DFI RS13655
gene id: 317577:DFI_RS13655
uniprot id: A0A221SZ16
names: Function
names: Similarity
messages: Belongs to the BCKDHA family.
messages: The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).

317577:DFI RS09565
gene id: 317577:DFI_RS09565
uniprot id: A0A221SX50
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

317577:DFI RS17050
gene id: 317577:DFI_RS17050
uniprot id: A0A221T1W5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

317577:DFI RS10870
gene id: 317577:DFI_RS10870
uniprot id: A0A221SXS6
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

317577:DFI RS09080
gene id: 317577:DFI_RS09080
uniprot id: A0A221SWW4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

317577:DFI RS09540
gene id: 317577:DFI_RS09540
uniprot id: A0A221SX55
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Binds a copper A center.
messages: Cell membrane
messages: Membrane
messages: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).

317577:DFI RS13190
gene id: 317577:DFI_RS13190
uniprot id: A0A221SYU8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

317577:DFI RS19835
gene id: 317577:DFI_RS19835
uniprot id: A0A221T3I4
names: Similarity
messages: Belongs to the BMP lipoprotein family.

317577:DFI RS03565
gene id: 317577:DFI_RS03565
uniprot id: A0A221SUB4
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

317577:DFI RS05005
gene id: 317577:DFI_RS05005
uniprot id: A0A221SUY3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

317577:DFI RS04925
gene id: 317577:DFI_RS04925
uniprot id: A0A221SUY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

317577:DFI RS10920
gene id: 317577:DFI_RS10920
uniprot id: A0A221SXU9
names: Similarity
messages: Belongs to the peptidase C40 family.

317577:DFI RS01365
gene id: 317577:DFI_RS01365
uniprot id: A0A221ST67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

317577:DFI RS15135
gene id: 317577:DFI_RS15135
uniprot id: A0A221T0T5
names: Subcellular Location Annotation
messages: Membrane

317577:DFI RS16780
gene id: 317577:DFI_RS16780
uniprot id: A0A221T1U2
names: Function
names: Similarity
messages: Belongs to the peptidase S51 family.
messages: Exopeptidase that catalyzes the hydrolytic cleavage of multi-L-arginyl-poly-L-aspartic acid (cyanophycin; a water-insoluble reserve polymer) into aspartate-arginine dipeptides.

317577:DFI RS01880
gene id: 317577:DFI_RS01880
uniprot id: A0A221STE9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

317577:DFI RS09100
gene id: 317577:DFI_RS09100
uniprot id: A0A221SZQ1
names: Similarity
messages: Belongs to the disproportionating enzyme family.

317577:DFI RS05795
gene id: 317577:DFI_RS05795
uniprot id: A0A221SVC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 13 family.
messages: Cytoplasm

317577:DFI RS08470
gene id: 317577:DFI_RS08470
uniprot id: A0A221SWK9
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

317577:DFI RS00385
gene id: 317577:DFI_RS00385
uniprot id: A0A221SSP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

317577:DFI RS06940
gene id: 317577:DFI_RS06940
uniprot id: A0A221SVV0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

317577:DFI RS13335
gene id: 317577:DFI_RS13335
uniprot id: A0A221SYW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

317577:DFI RS07985
gene id: 317577:DFI_RS07985
uniprot id: A0A221SWC3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

317577:DFI RS10205
gene id: 317577:DFI_RS10205
uniprot id: A0A221SXH2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OadG family.
messages: Catalyzes the decarboxylation of oxaloacetate coupled to Na(+) translocation.
messages: Cell membrane

317577:DFI RS06950
gene id: 317577:DFI_RS06950
uniprot id: A0A221SVX4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

317577:DFI RS03200
gene id: 317577:DFI_RS03200
uniprot id: A0A221SZ95
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TtcA family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is chelated by three Cys residues, the fourth Fe has a free coordination site that may bind a sulfur atom transferred from the persulfide of IscS.
messages: Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
messages: Cytoplasm
messages: Homodimer.
messages: The thiolation reaction likely consists of two steps: a first activation step by ATP to form an adenylated intermediate of the target base of tRNA, and a second nucleophilic substitution step of the sulfur (S) atom supplied by the hydrosulfide attached to the Fe-S cluster.

317577:DFI RS09395
gene id: 317577:DFI_RS09395
uniprot id: A0A221SZS2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably interacts with PlsX.

317577:DFI RS10020
gene id: 317577:DFI_RS10020
uniprot id: A0A221SXH9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

317577:DFI RS02890
gene id: 317577:DFI_RS02890
uniprot id: A0A221STX9
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

317577:DFI RS03260
gene id: 317577:DFI_RS03260
uniprot id: A0A221SZE7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

317577:DFI RS08735
gene id: 317577:DFI_RS08735
uniprot id: A0A221SWQ4
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

317577:DFI RS11850
gene id: 317577:DFI_RS11850
uniprot id: A0A221SYB6
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

317577:DFI RS00275
gene id: 317577:DFI_RS00275
uniprot id: A0A221SSM7
names: Cofactor
names: Similarity
messages: Belongs to the nitroreductase family.
messages: Binds 1 FMN per subunit.

317577:DFI RS12085
gene id: 317577:DFI_RS12085
uniprot id: A0A221SYF9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

317577:DFI RS06440
gene id: 317577:DFI_RS06440
uniprot id: A0A221SVM5
names: Subcellular Location Annotation
messages: Membrane

317577:DFI RS13765
gene id: 317577:DFI_RS13765
uniprot id: A0A221T045
names: Subcellular Location Annotation
messages: Membrane

317577:DFI RS09410
gene id: 317577:DFI_RS09410
uniprot id: A0A221SX42
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

317577:DFI RS03220
gene id: 317577:DFI_RS03220
uniprot id: A0A221SZB3
names: Subcellular Location Annotation
messages: Membrane

317577:DFI RS05960
gene id: 317577:DFI_RS05960
uniprot id: A0A221SVC3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

317577:DFI RS01810
gene id: 317577:DFI_RS01810
uniprot id: A0A221STF2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

317577:DFI RS13650
gene id: 317577:DFI_RS13650
uniprot id: A0A221SZ27
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MnmG family.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

317577:DFI RS01245
gene id: 317577:DFI_RS01245
uniprot id: A0A221ST50
names: Similarity
messages: Belongs to the GSP E family.

317577:DFI RS11880
gene id: 317577:DFI_RS11880
uniprot id: A0A221SYA4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

317577:DFI RS16245
gene id: 317577:DFI_RS16245
uniprot id: A0A221T1P7
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

317577:DFI RS02730
gene id: 317577:DFI_RS02730
uniprot id: A0A221STV6
names: Similarity
messages: Belongs to the Nudix hydrolase family.

317577:DFI RS11380
gene id: 317577:DFI_RS11380
uniprot id: A0A221SXZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

317577:DFI RS17870
gene id: 317577:DFI_RS17870
uniprot id: A0A221T2C1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

317577:DFI RS05625
gene id: 317577:DFI_RS05625
uniprot id: A0A221SV95
names: Similarity
messages: Belongs to the PGI/PMI family.

317577:DFI RS06980
gene id: 317577:DFI_RS06980
uniprot id: A0A221SVX1
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

317577:DFI RS05460
gene id: 317577:DFI_RS05460
uniprot id: A0A221SV55
names: Similarity
messages: Belongs to the band 7/mec-2 family.

317577:DFI RS01805
gene id: 317577:DFI_RS01805
uniprot id: A0A221STE5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

317577:DFI RS04690
gene id: 317577:DFI_RS04690
uniprot id: A0A221SZD5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

317577:DFI RS07945
gene id: 317577:DFI_RS07945
uniprot id: A0A221SWE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

317577:DFI RS09610
gene id: 317577:DFI_RS09610
uniprot id: A0A221SX71
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

317577:DFI RS10215
gene id: 317577:DFI_RS10215
uniprot id: A0A221SXH1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

317577:DFI RS04810
gene id: 317577:DFI_RS04810
uniprot id: A0A221SUW0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PNT beta subunit family.
messages: Cell inner membrane
messages: Membrane
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

317577:DFI RS16715
gene id: 317577:DFI_RS16715
uniprot id: A0A221T1Q5
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

317577:DFI RS19620
gene id: 317577:DFI_RS19620
uniprot id: A0A221T3G5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

317577:DFI RS00820
gene id: 317577:DFI_RS00820
uniprot id: A0A221SSW5
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

317577:DFI RS09205
gene id: 317577:DFI_RS09205
uniprot id: A0A221SWY8
names: Similarity
messages: Belongs to the Nudix hydrolase family.

317577:DFI RS05995
gene id: 317577:DFI_RS05995
uniprot id: A0A221SVE8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

317577:DFI RS02235
gene id: 317577:DFI_RS02235
uniprot id: A0A221STK2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

317577:DFI RS06730
gene id: 317577:DFI_RS06730
uniprot id: A0A221SVR9
names: Function
names: Similarity
messages: Belongs to the RlpA family.
messages: Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.

317577:DFI RS00020
gene id: 317577:DFI_RS00020
uniprot id: A0A221SSI1
names: Similarity
messages: Belongs to the pyruvate kinase family.

317577:DFI RS18040
gene id: 317577:DFI_RS18040
uniprot id: A0A221T2J5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

317577:DFI RS13100
gene id: 317577:DFI_RS13100
uniprot id: A0A221SYX7
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

317577:DFI RS17925
gene id: 317577:DFI_RS17925
uniprot id: A0A221T2D1
names: Similarity
messages: In the N-terminal section; belongs to the phytochrome family.

317577:DFI RS00525
gene id: 317577:DFI_RS00525
uniprot id: A0A221SSR8
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

317577:DFI RS07690
gene id: 317577:DFI_RS07690
uniprot id: A0A221SW84
names: Subcellular Location Annotation
messages: Cytoplasm

317577:DFI RS18595
gene id: 317577:DFI_RS18595
uniprot id: A0A221T2X0
names: Similarity
messages: Belongs to the leucine-binding protein family.

317577:DFI RS09095
gene id: 317577:DFI_RS09095
uniprot id: A0A221SWW3
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

317577:DFI RS06995
gene id: 317577:DFI_RS06995
uniprot id: A0A221SVW0
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

317577:DFI RS17895
gene id: 317577:DFI_RS17895
uniprot id: A0A221T2H1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

317577:DFI RS11980
gene id: 317577:DFI_RS11980
uniprot id: A0A221SY84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

317577:DFI RS05720
gene id: 317577:DFI_RS05720
uniprot id: A0A221SV89
names: Similarity
messages: Belongs to the threonine aldolase family.

317577:DFI RS02535
gene id: 317577:DFI_RS02535
uniprot id: A0A221STQ1
names: Function
names: Similarity
messages: ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.
messages: Belongs to the ParA family. MinD subfamily.

317577:DFI RS02410
gene id: 317577:DFI_RS02410
uniprot id: A0A221STM8
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

317577:DFI RS01500
gene id: 317577:DFI_RS01500
uniprot id: A0A221ST99
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

317577:DFI RS02515
gene id: 317577:DFI_RS02515
uniprot id: A0A221STQ4
names: Subcellular Location Annotation
messages: Membrane

317577:DFI RS03590
gene id: 317577:DFI_RS03590
uniprot id: A0A221SUD0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

317577:DFI RS10925
gene id: 317577:DFI_RS10925
uniprot id: A0A221SXS8
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

317577:DFI RS12710
gene id: 317577:DFI_RS12710
uniprot id: A0A221SYK8
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Periplasm

317577:DFI RS12210
gene id: 317577:DFI_RS12210
uniprot id: A0A221SYD1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LuxS family.
messages: Binds 1 Fe cation per subunit.
messages: Homodimer.
messages: Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).

317577:DFI RS06400
gene id: 317577:DFI_RS06400
uniprot id: A0A221SVK8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

317577:DFI RS05665
gene id: 317577:DFI_RS05665
uniprot id: A0A221SV74
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

317577:DFI RS00845
gene id: 317577:DFI_RS00845
uniprot id: A0A221SSY4
names: Similarity
messages: Belongs to the SAICAR synthetase family.

317577:DFI RS15125
gene id: 317577:DFI_RS15125
uniprot id: A0A221T0U1
names: Subcellular Location Annotation
messages: Membrane

317577:DFI RS06775
gene id: 317577:DFI_RS06775
uniprot id: A0A221SVS2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

317577:DFI RS11725
gene id: 317577:DFI_RS11725
uniprot id: A0A221SY98
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

317577:DFI RS09865
gene id: 317577:DFI_RS09865
uniprot id: A0A221SX94
names: Similarity
messages: Belongs to the asp23 family.

317577:DFI RS09060
gene id: 317577:DFI_RS09060
uniprot id: A0A221SWV8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Cytoplasm
messages: Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

317577:DFI RS00605
gene id: 317577:DFI_RS00605
uniprot id: A0A221SST2
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

317577:DFI RS00700
gene id: 317577:DFI_RS00700
uniprot id: A0A221SSV4
names: Similarity
messages: Belongs to the Nth/MutY family.

317577:DFI RS02660
gene id: 317577:DFI_RS02660
uniprot id: A0A221STU3
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

317577:DFI RS08755
gene id: 317577:DFI_RS08755
uniprot id: A0A221SWQ6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

317577:DFI RS03190
gene id: 317577:DFI_RS03190
uniprot id: A0A221SU34
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

317577:DFI RS04645
gene id: 317577:DFI_RS04645
uniprot id: A0A221SUU7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

317577:DFI RS08825
gene id: 317577:DFI_RS08825
uniprot id: A0A221SWX4
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family.

317577:DFI RS02270
gene id: 317577:DFI_RS02270
uniprot id: A0A221STM6
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

317577:DFI RS02540
gene id: 317577:DFI_RS02540
uniprot id: A0A221STS2
names: Function
names: Similarity
messages: Belongs to the MinE family.
messages: Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.

317577:DFI RS05395
gene id: 317577:DFI_RS05395
uniprot id: A0A221SV45
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

317577:DFI RS17150
gene id: 317577:DFI_RS17150
uniprot id: A0A221T1Y0
names: Function
names: Similarity
messages: Belongs to the phenylacetyl-CoA ligase family.
messages: Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).

317577:DFI RS07165
gene id: 317577:DFI_RS07165
uniprot id: A0A221SVY7
names: Similarity
messages: Belongs to the UPF0225 family.

317577:DFI RS12325
gene id: 317577:DFI_RS12325
uniprot id: A0A221SYE3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

317577:DFI RS06425
gene id: 317577:DFI_RS06425
uniprot id: A0A221SVK5
names: Similarity
messages: Belongs to the FtsK/SpoIIIE/SftA family.

317577:DFI RS06360
gene id: 317577:DFI_RS06360
uniprot id: A0A221SVK7
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PSRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.

317577:DFI RS04000
gene id: 317577:DFI_RS04000
uniprot id: A0A221SUH2
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

317577:DFI RS16825
gene id: 317577:DFI_RS16825
uniprot id: A0A221T2I8
names: Similarity
messages: Belongs to the UDP-galactopyranose/dTDP-fucopyranose mutase family.

317577:DFI RS17620
gene id: 317577:DFI_RS17620
uniprot id: A0A221T273
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

317577:DFI RS19900
gene id: 317577:DFI_RS19900
uniprot id: A0A221T3M3
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

317577:DFI RS10545
gene id: 317577:DFI_RS10545
uniprot id: A0A221SXL5
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit A family.

317577:DFI RS10610
gene id: 317577:DFI_RS10610
uniprot id: A0A221SXN0
names: Similarity
names: Subunit
messages: Belongs to the beta-eliminating lyase family.
messages: Homotetramer.

317577:DFI RS04920
gene id: 317577:DFI_RS04920
uniprot id: A0A221SUW4
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

317577:DFI RS08555
gene id: 317577:DFI_RS08555
uniprot id: A0A221SWM0
names: Similarity
messages: Belongs to the CinA family.

317577:DFI RS09260
gene id: 317577:DFI_RS09260
uniprot id: A0A221SX05
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

317577:DFI RS14725
gene id: 317577:DFI_RS14725
uniprot id: A0A221T0K2
names: Similarity
messages: Belongs to the proline racemase family.

317577:DFI RS11995
gene id: 317577:DFI_RS11995
uniprot id: A0A221SZW9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

317577:DFI RS03490
gene id: 317577:DFI_RS03490
uniprot id: A0A221SU70
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

317577:DFI RS11635
gene id: 317577:DFI_RS11635
uniprot id: A0A221T023
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

317577:DFI RS18015
gene id: 317577:DFI_RS18015
uniprot id: A0A221T2I6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

317577:DFI RS12170
gene id: 317577:DFI_RS12170
uniprot id: A0A221SYG0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M32 family.
messages: Binds 1 zinc ion per subunit.
messages: Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues.

317577:DFI RS12260
gene id: 317577:DFI_RS12260
uniprot id: A0A221SYE1
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

317577:DFI RS11735
gene id: 317577:DFI_RS11735
uniprot id: A0A221SY49
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

317577:DFI RS03650
gene id: 317577:DFI_RS03650
uniprot id: A0A221SUD1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

317577:DFI RS05185
gene id: 317577:DFI_RS05185
uniprot id: A0A221SV37
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

317577:DFI RS07415
gene id: 317577:DFI_RS07415
uniprot id: A0A221SW46
names: Similarity
messages: Belongs to the FemABX family.

317577:DFI RS17940
gene id: 317577:DFI_RS17940
uniprot id: A0A221T2C0
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

317577:DFI RS10705
gene id: 317577:DFI_RS10705
uniprot id: A0A221SXT5
names: Similarity
messages: Belongs to the dGTPase family. Type 2 subfamily.

317577:DFI RS01815
gene id: 317577:DFI_RS01815
uniprot id: A0A221STE4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

317577:DFI RS02035
gene id: 317577:DFI_RS02035
uniprot id: A0A221STH8
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

317577:DFI RS06595
gene id: 317577:DFI_RS06595
uniprot id: A0A221SVQ0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

317577:DFI RS09440
gene id: 317577:DFI_RS09440
uniprot id: A0A221SX39
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.

317577:DFI RS06160
gene id: 317577:DFI_RS06160
uniprot id: A0A221SVK9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

317577:DFI RS01035
gene id: 317577:DFI_RS01035
uniprot id: A0A221ST16
names: Similarity
messages: Belongs to the UbiD family.

317577:DFI RS16180
gene id: 317577:DFI_RS16180
uniprot id: A0A221T1D4
names: Similarity
messages: Belongs to the manganese catalase family.

317577:DFI RS06145
gene id: 317577:DFI_RS06145
uniprot id: A0A221SVI1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

317577:DFI RS04305
gene id: 317577:DFI_RS04305
uniprot id: A0A221SUL2
names: Similarity
messages: Belongs to the Fur family.

317577:DFI RS16965
gene id: 317577:DFI_RS16965
uniprot id: A0A221T1V9
names: Similarity
messages: Belongs to the peptidase S8 family.

317577:DFI RS01520
gene id: 317577:DFI_RS01520
uniprot id: A0A221STA3
names: Similarity
messages: Belongs to the flavin oxidoreductase frp family.

317577:DFI RS17585
gene id: 317577:DFI_RS17585
uniprot id: A0A221T257
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

317577:DFI RS08385
gene id: 317577:DFI_RS08385
uniprot id: A0A221SWJ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homotetramer.

317577:DFI RS15280
gene id: 317577:DFI_RS15280
uniprot id: A0A221T1P8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

317577:DFI RS06195
gene id: 317577:DFI_RS06195
uniprot id: A0A221SVH5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

317577:DFI RS08125
gene id: 317577:DFI_RS08125
uniprot id: A0A221SWH3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

317577:DFI RS16260
gene id: 317577:DFI_RS16260
uniprot id: A0A221T1H6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

317577:DFI RS15190
gene id: 317577:DFI_RS15190
uniprot id: A0A221T0U9
names: Subcellular Location Annotation
messages: Membrane

317577:DFI RS16520
gene id: 317577:DFI_RS16520
uniprot id: A0A221T1M7
names: Subcellular Location Annotation
messages: Cytoplasm

317577:DFI RS10075
gene id: 317577:DFI_RS10075
uniprot id: A0A221SXI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell membrane
messages: Membrane

317577:DFI RS01800
gene id: 317577:DFI_RS01800
uniprot id: A0A221STD9
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

317577:DFI RS09985
gene id: 317577:DFI_RS09985
uniprot id: A0A221SXE2
names: Similarity
messages: Belongs to the leucine-binding protein family.

317577:DFI RS01615
gene id: 317577:DFI_RS01615
uniprot id: A0A221STB6
names: Similarity
messages: Belongs to the IMPACT family.

317577:DFI RS05205
gene id: 317577:DFI_RS05205
uniprot id: A0A221SV16
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

317577:DFI RS13160
gene id: 317577:DFI_RS13160
uniprot id: A0A221SYT0
names: Subcellular Location Annotation
messages: Membrane

317577:DFI RS01060
gene id: 317577:DFI_RS01060
uniprot id: A0A221ST05
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 2 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

317577:DFI RS12040
gene id: 317577:DFI_RS12040
uniprot id: A0A221SY95
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

317577:DFI RS08680
gene id: 317577:DFI_RS08680
uniprot id: A0A221SWP5
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

317577:DFI RS12235
gene id: 317577:DFI_RS12235
uniprot id: A0A221SYD5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

317577:DFI RS17705
gene id: 317577:DFI_RS17705
uniprot id: A0A221T282
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tryptophan 2,3-dioxygenase family.
messages: Binds 1 heme group per subunit.
messages: Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L-tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

317577:DFI RS10715
gene id: 317577:DFI_RS10715
uniprot id: A0A221SZU5
names: Similarity
messages: Belongs to the ribF family.

317577:DFI RS07355
gene id: 317577:DFI_RS07355
uniprot id: A0A221SW22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Membrane

317577:DFI RS02960
gene id: 317577:DFI_RS02960
uniprot id: A0A221STX0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

317577:DFI RS09545
gene id: 317577:DFI_RS09545
uniprot id: A0A221SZS7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: Membrane

317577:DFI RS05805
gene id: 317577:DFI_RS05805
uniprot id: A0A221SVC7
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

317577:DFI RS01865
gene id: 317577:DFI_RS01865
uniprot id: A0A221STG1
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

317577:DFI RS11155
gene id: 317577:DFI_RS11155
uniprot id: A0A221SXX1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

317577:DFI RS17445
gene id: 317577:DFI_RS17445
uniprot id: A0A221T281
names: Similarity
messages: Belongs to the extradiol ring-cleavage dioxygenase family.

317577:DFI RS06650
gene id: 317577:DFI_RS06650
uniprot id: A0A221SVQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

317577:DFI RS04195
gene id: 317577:DFI_RS04195
uniprot id: A0A221SUJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

317577:DFI RS00060
gene id: 317577:DFI_RS00060
uniprot id: A0A221SSJ5
names: Caution
names: Function
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

317577:DFI RS00350
gene id: 317577:DFI_RS00350
uniprot id: A0A221SSN9
names: Subcellular Location Annotation
messages: Membrane

317577:DFI RS00220
gene id: 317577:DFI_RS00220
uniprot id: A0A221SSL9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.
messages: Ca(+)/H(+) antiporter that extrudes calcium in exchange for external protons.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

317577:DFI RS12610
gene id: 317577:DFI_RS12610
uniprot id: A0A221SYI2
names: Similarity
messages: Belongs to the RutC family.

317577:DFI RS05825
gene id: 317577:DFI_RS05825
uniprot id: A0A221SVA8
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

317577:DFI RS18000
gene id: 317577:DFI_RS18000
uniprot id: A0A221T2F5
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

317577:DFI RS05290
gene id: 317577:DFI_RS05290
uniprot id: A0A221SV31
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

317577:DFI RS06900
gene id: 317577:DFI_RS06900
uniprot id: A0A221SVT5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

317577:DFI RS17670
gene id: 317577:DFI_RS17670
uniprot id: A0A221T283
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

317577:DFI RS08355
gene id: 317577:DFI_RS08355
uniprot id: A0A221SWL8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

317577:DFI RS17460
gene id: 317577:DFI_RS17460
uniprot id: A0A221T240
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

317577:DFI RS17105
gene id: 317577:DFI_RS17105
uniprot id: A0A221T1X5
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

317577:DFI RS10095
gene id: 317577:DFI_RS10095
uniprot id: A0A221SXG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

317577:DFI RS03505
gene id: 317577:DFI_RS03505
uniprot id: A0A221SU82
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

317577:DFI RS07925
gene id: 317577:DFI_RS07925
uniprot id: A0A221SZL9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

317577:DFI RS03400
gene id: 317577:DFI_RS03400
uniprot id: A0A221SU67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

317577:DFI RS08010
gene id: 317577:DFI_RS08010
uniprot id: A0A221SWC7
names: Similarity
messages: Belongs to the DNA glycosylase MPG family.

317577:DFI RS15150
gene id: 317577:DFI_RS15150
uniprot id: A0A221T0T8
names: Subcellular Location Annotation
messages: Membrane

317577:DFI RS10520
gene id: 317577:DFI_RS10520
uniprot id: A0A221SXL0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

317577:DFI RS07130
gene id: 317577:DFI_RS07130
uniprot id: A0A221SW09
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

317577:DFI RS13105
gene id: 317577:DFI_RS13105
uniprot id: A0A221SYS6
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

317577:DFI RS03055
gene id: 317577:DFI_RS03055
uniprot id: A0A221STZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

317577:DFI RS09030
gene id: 317577:DFI_RS09030
uniprot id: A0A221SZU8
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

317577:DFI RS01220
gene id: 317577:DFI_RS01220
uniprot id: A0A221SZ96
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

317577:DFI RS07620
gene id: 317577:DFI_RS07620
uniprot id: A0A221SW60
names: Subcellular Location Annotation
messages: Membrane

317577:DFI RS01525
gene id: 317577:DFI_RS01525
uniprot id: A0A221STA0
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

317577:DFI RS08930
gene id: 317577:DFI_RS08930
uniprot id: A0A221SWT6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urocanase family.
messages: Binds 1 NAD(+) per subunit.
messages: Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
messages: Cytoplasm

317577:DFI RS03780
gene id: 317577:DFI_RS03780
uniprot id: A0A221SUF6
names: Subcellular Location Annotation
messages: Membrane

317577:DFI RS17695
gene id: 317577:DFI_RS17695
uniprot id: A0A221T2C4
names: Subcellular Location Annotation
messages: Membrane

317577:DFI RS04495
gene id: 317577:DFI_RS04495
uniprot id: A0A221SUP7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

317577:DFI RS10765
gene id: 317577:DFI_RS10765
uniprot id: A0A221SXU6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

317577:DFI RS00255
gene id: 317577:DFI_RS00255
uniprot id: A0A221SSM6
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.

317577:DFI RS05785
gene id: 317577:DFI_RS05785
uniprot id: A0A221SV93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

317577:DFI RS03695
gene id: 317577:DFI_RS03695
uniprot id: A0A221SUB1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

317577:DFI RS10595
gene id: 317577:DFI_RS10595
uniprot id: A0A221SXM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

317577:DFI RS08850
gene id: 317577:DFI_RS08850
uniprot id: A0A221SWV7
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

317577:DFI RS05885
gene id: 317577:DFI_RS05885
uniprot id: A0A221SVB9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

317577:DFI RS17070
gene id: 317577:DFI_RS17070
uniprot id: A0A221T1X8
names: Similarity
messages: Belongs to the cytochrome P450 family.

317577:DFI RS07530
gene id: 317577:DFI_RS07530
uniprot id: A0A221SW81
names: Similarity
messages: Belongs to the peptidase S1C family.

317577:DFI RS19120
gene id: 317577:DFI_RS19120
uniprot id: A0A221T340
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

317577:DFI RS16920
gene id: 317577:DFI_RS16920
uniprot id: A0A221T1V2
names: Subcellular Location Annotation
messages: Membrane

317577:DFI RS13905
gene id: 317577:DFI_RS13905
uniprot id: A0A221T051
names: Function
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 2 subfamily.
messages: Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 2-succinylbenzoate (OSB).

317577:DFI RS11215
gene id: 317577:DFI_RS11215
uniprot id: A0A221SXZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

317577:DFI RS13175
gene id: 317577:DFI_RS13175
uniprot id: A0A221SYY2
names: Similarity
messages: Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family.

317577:DFI RS10100
gene id: 317577:DFI_RS10100
uniprot id: A0A221SXG6
names: Similarity
messages: Belongs to the glycosyl hydrolase 32 family.

317577:DFI RS07115
gene id: 317577:DFI_RS07115
uniprot id: A0A221SW02
names: Similarity
messages: Belongs to the Skp family.

317577:DFI RS11870
gene id: 317577:DFI_RS11870
uniprot id: A0A221SYA6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

317577:DFI RS17010
gene id: 317577:DFI_RS17010
uniprot id: A0A221T205
names: Subcellular Location Annotation
messages: Membrane

317577:DFI RS06190
gene id: 317577:DFI_RS06190
uniprot id: A0A221SVG3
names: Function
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family. Futalosine hydrolase subfamily.
messages: Catalyzes the hydrolysis of futalosine (FL) to dehypoxanthine futalosine (DHFL) and hypoxanthine, a step in the biosynthesis of menaquinone (MK, vitamin K2).

317577:DFI RS08250
gene id: 317577:DFI_RS08250
uniprot id: A0A221SWH9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

317577:DFI RS03825
gene id: 317577:DFI_RS03825
uniprot id: A0A221SUH0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.
messages: In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: In the N-terminal section; belongs to the MIP18 family.

317577:DFI RS06355
gene id: 317577:DFI_RS06355
uniprot id: A0A221SVJ4
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

317577:DFI RS00175
gene id: 317577:DFI_RS00175
uniprot id: A0A221SSK6
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

317577:DFI RS09795
gene id: 317577:DFI_RS09795
uniprot id: A0A221SX86
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

317577:DFI RS01140
gene id: 317577:DFI_RS01140
uniprot id: A0A221ST26
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

317577:DFI RS05955
gene id: 317577:DFI_RS05955
uniprot id: A0A221SVC9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C15 family.
messages: Cytoplasm
messages: Removes 5-oxoproline from various penultimate amino acid residues except L-proline.

317577:DFI RS11975
gene id: 317577:DFI_RS11975
uniprot id: A0A221SY85
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 15 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

317577:DFI RS00870
gene id: 317577:DFI_RS00870
uniprot id: A0A221SSX5
names: Subcellular Location Annotation
messages: Membrane

317577:DFI RS07450
gene id: 317577:DFI_RS07450
uniprot id: A0A221SW30
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

317577:DFI RS12620
gene id: 317577:DFI_RS12620
uniprot id: A0A221SYK0
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

317577:DFI RS01055
gene id: 317577:DFI_RS01055
uniprot id: A0A221ST20
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

317577:DFI RS04700
gene id: 317577:DFI_RS04700
uniprot id: A0A221SUV5
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

317577:DFI RS09690
gene id: 317577:DFI_RS09690
uniprot id: A0A221SX88
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

317577:DFI RS05700
gene id: 317577:DFI_RS05700
uniprot id: A0A221SZL1
names: Function
names: Similarity
messages: Belongs to the RecD family. RecD-like subfamily.
messages: DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity.

317577:DFI RS02975
gene id: 317577:DFI_RS02975
uniprot id: A0A221SU12
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

317577:DFI RS03495
gene id: 317577:DFI_RS03495
uniprot id: A0A221SUA1
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

317577:DFI RS03100
gene id: 317577:DFI_RS03100
uniprot id: A0A221SU32
names: Similarity
messages: Belongs to the AlaDH/PNT family.

317577:DFI RS07545
gene id: 317577:DFI_RS07545
uniprot id: A0A221SW61
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

317577:DFI RS10115
gene id: 317577:DFI_RS10115
uniprot id: A0A221SXF0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
messages: Homotetramer.

317577:DFI RS01910
gene id: 317577:DFI_RS01910
uniprot id: A0A221STG2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

317577:DFI RS08900
gene id: 317577:DFI_RS08900
uniprot id: A0A221SWS9
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

317577:DFI RS10540
gene id: 317577:DFI_RS10540
uniprot id: A0A221SXL6
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

317577:DFI RS02985
gene id: 317577:DFI_RS02985
uniprot id: A0A221STK0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

317577:DFI RS13690
gene id: 317577:DFI_RS13690
uniprot id: A0A221SZ60
names: Similarity
messages: Belongs to the DprA/Smf family.

317577:DFI RS01070
gene id: 317577:DFI_RS01070
uniprot id: A0A221ST19
names: Similarity
messages: Belongs to the aminoglycoside phosphotransferase family.

317577:DFI RS04655
gene id: 317577:DFI_RS04655
uniprot id: A0A221SUS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

317577:DFI RS15245
gene id: 317577:DFI_RS15245
uniprot id: A0A221T0V5
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

317577:DFI RS16370
gene id: 317577:DFI_RS16370
uniprot id: A0A221T1G1
names: Similarity
messages: Belongs to the DinB family.

317577:DFI RS10255
gene id: 317577:DFI_RS10255
uniprot id: A0A221SXG5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M32 family.
messages: Binds 1 zinc ion per subunit.
messages: Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues.

317577:DFI RS04145
gene id: 317577:DFI_RS04145
uniprot id: A0A221SUM1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

317577:DFI RS07225
gene id: 317577:DFI_RS07225
uniprot id: A0A221SVZ7
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

317577:DFI RS05500
gene id: 317577:DFI_RS05500
uniprot id: A0A221SV75
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

317577:DFI RS07935
gene id: 317577:DFI_RS07935
uniprot id: A0A221SWA9
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

317577:DFI RS17180
gene id: 317577:DFI_RS17180
uniprot id: A0A221T236
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

317577:DFI RS12245
gene id: 317577:DFI_RS12245
uniprot id: A0A221SYG8
names: Similarity
messages: Belongs to the asparaginase 1 family.

317577:DFI RS02295
gene id: 317577:DFI_RS02295
uniprot id: A0A221STL7
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

317577:DFI RS05875
gene id: 317577:DFI_RS05875
uniprot id: A0A221SVC6
names: Subcellular Location Annotation
messages: Membrane

317577:DFI RS00480
gene id: 317577:DFI_RS00480
uniprot id: A0A221SSR5
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

317577:DFI RS08375
gene id: 317577:DFI_RS08375
uniprot id: A0A221SWI5
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

317577:DFI RS03385
gene id: 317577:DFI_RS03385
uniprot id: A0A221SU52
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

317577:DFI RS10325
gene id: 317577:DFI_RS10325
uniprot id: A0A221SXK6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.
messages: Cytoplasm
messages: Homodimer.

317577:DFI RS00690
gene id: 317577:DFI_RS00690
uniprot id: A0A221SSV1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

317577:DFI RS00050
gene id: 317577:DFI_RS00050
uniprot id: A0A221SSJ0
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

317577:DFI RS09600
gene id: 317577:DFI_RS09600
uniprot id: A0A221SX80
names: Similarity
messages: Belongs to the YciI family.

317577:DFI RS10485
gene id: 317577:DFI_RS10485
uniprot id: A0A221SXK2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm
messages: Homodimer.

317577:DFI RS08165
gene id: 317577:DFI_RS08165
uniprot id: A0A221SWJ8
names: Subcellular Location Annotation
messages: Membrane

317577:DFI RS13075
gene id: 317577:DFI_RS13075
uniprot id: A0A221SYV7
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

317577:DFI RS01595
gene id: 317577:DFI_RS01595
uniprot id: A0A221ST90
names: Similarity
messages: Belongs to the peptidase M29 family.

317577:DFI RS12425
gene id: 317577:DFI_RS12425
uniprot id: A0A221SYJ9
names: Similarity
messages: Belongs to the myoviridae tail sheath protein family.

317577:DFI RS11115
gene id: 317577:DFI_RS11115
uniprot id: A0A221SXV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Cell membrane
messages: Membrane

317577:DFI RS15580
gene id: 317577:DFI_RS15580
uniprot id: A0A221T147
names: Similarity
messages: Belongs to the peptidase S51 family.

317577:DFI RS12080
gene id: 317577:DFI_RS12080
uniprot id: A0A221SYA3
names: Similarity
messages: Belongs to the Nudix hydrolase family.

317577:DFI RS12225
gene id: 317577:DFI_RS12225
uniprot id: A0A221SYC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

317577:DFI RS19055
gene id: 317577:DFI_RS19055
uniprot id: A0A221T362
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

317577:DFI RS12150
gene id: 317577:DFI_RS12150
uniprot id: A0A221SYB9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

317577:DFI RS02655
gene id: 317577:DFI_RS02655
uniprot id: A0A221STU1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

317577:DFI RS06025
gene id: 317577:DFI_RS06025
uniprot id: A0A221SVE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

317577:DFI RS02345
gene id: 317577:DFI_RS02345
uniprot id: A0A221STL8
names: Subcellular Location Annotation
messages: Membrane

317577:DFI RS17755
gene id: 317577:DFI_RS17755
uniprot id: A0A221T287
names: Similarity
messages: Belongs to the BMP lipoprotein family.

317577:DFI RS04530
gene id: 317577:DFI_RS04530
uniprot id: A0A221SUQ5
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

317577:DFI RS06010
gene id: 317577:DFI_RS06010
uniprot id: A0A221SVD8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

317577:DFI RS02705
gene id: 317577:DFI_RS02705
uniprot id: A0A221STV0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

317577:DFI RS09930
gene id: 317577:DFI_RS09930
uniprot id: A0A221SXD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial secretin family.
messages: Cell outer membrane

317577:DFI RS12370
gene id: 317577:DFI_RS12370
uniprot id: A0A221SYJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Membrane

317577:DFI RS10045
gene id: 317577:DFI_RS10045
uniprot id: A0A221SXF3
names: Similarity
messages: Belongs to the ClpA/ClpB family.

317577:DFI RS11355
gene id: 317577:DFI_RS11355
uniprot id: A0A221SXY6
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the MsrP family.
messages: Binds 1 Mo-molybdopterin (Mo-MPT) cofactor per subunit.
messages: Heterodimer of a catalytic subunit (MsrP) and a heme-binding subunit (MsrQ).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the MsrPQ system that repairs oxidized cell envelope proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated cell envelope proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide.
messages: Predicted to be exported by the Tat system. The position of the signal peptide cleavage has not been experimentally proven.

317577:DFI RS05465
gene id: 317577:DFI_RS05465
uniprot id: A0A221SV49
names: Subcellular Location Annotation
messages: Membrane

317577:DFI RS01580
gene id: 317577:DFI_RS01580
uniprot id: A0A221ST96
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

317577:DFI RS13875
gene id: 317577:DFI_RS13875
uniprot id: A0A221T050
names: Similarity
messages: Belongs to the iron-containing alcohol dehydrogenase family.

317577:DFI RS08320
gene id: 317577:DFI_RS08320
uniprot id: A0A221SWI0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

317577:DFI RS08420
gene id: 317577:DFI_RS08420
uniprot id: A0A221SWK4
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

317577:DFI RS00415
gene id: 317577:DFI_RS00415
uniprot id: A0A221SSP8
names: Cofactor
names: Similarity
messages: Belongs to the peptidase S45 family.
messages: Binds 1 Ca(2+) ion per dimer.

317577:DFI RS16020
gene id: 317577:DFI_RS16020
uniprot id: A0A221T1C1
names: Similarity
messages: Belongs to the DapA family.

317577:DFI RS03790
gene id: 317577:DFI_RS03790
uniprot id: A0A221SUD2
names: Similarity
messages: Belongs to the cytochrome P450 family.

317577:DFI RS02510
gene id: 317577:DFI_RS02510
uniprot id: A0A221STP8
names: Similarity
messages: Belongs to the Nudix hydrolase family.

317577:DFI RS02970
gene id: 317577:DFI_RS02970
uniprot id: A0A221SU15
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

317577:DFI RS08915
gene id: 317577:DFI_RS08915
uniprot id: A0A221SWT3
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAL/histidase family.
messages: Contains an active site 4-methylidene-imidazol-5-one (MIO), which is formed autocatalytically by cyclization and dehydration of residues Ala-Ser-Gly.
messages: Cytoplasm

317577:DFI RS01485
gene id: 317577:DFI_RS01485
uniprot id: A0A221ST86
names: Similarity
messages: Belongs to the AAE transporter (TC 2.A.81) family.

317577:DFI RS04070
gene id: 317577:DFI_RS04070
uniprot id: A0A221SZC7
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

317577:DFI RS03065
gene id: 317577:DFI_RS03065
uniprot id: A0A221SU10
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

317577:DFI RS10495
gene id: 317577:DFI_RS10495
uniprot id: A0A221SZY2
names: Similarity
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.

317577:DFI RS15640
gene id: 317577:DFI_RS15640
uniprot id: A0A221T130
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArsB family.
messages: Cell membrane
messages: Involved in arsenical resistance. Thought to form the channel of an arsenite pump.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

317577:DFI RS09650
gene id: 317577:DFI_RS09650
uniprot id: A0A221SX75
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

317577:DFI RS02830
gene id: 317577:DFI_RS02830
uniprot id: A0A221STX6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the adenylate cyclase family. DacA/CdaA subfamily.
messages: Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably a homodimer.

317577:DFI RS09085
gene id: 317577:DFI_RS09085
uniprot id: A0A221SWX1
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

317577:DFI RS01605
gene id: 317577:DFI_RS01605
uniprot id: A0A221STA5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Could methylate the ribose at the nucleotide 34 wobble position in tRNA.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

317577:DFI RS03060
gene id: 317577:DFI_RS03060
uniprot id: A0A221SU16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

317577:DFI RS11000
gene id: 317577:DFI_RS11000
uniprot id: A0A221SXV8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

317577:DFI RS05270
gene id: 317577:DFI_RS05270
uniprot id: A0A221SV47
names: Similarity
messages: Belongs to the cytochrome P450 family.

317577:DFI RS13745
gene id: 317577:DFI_RS13745
uniprot id: A0A221T075
names: Similarity
messages: Belongs to the lysine N(6)-hydroxylase/L-ornithine N(5)-oxygenase family.

317577:DFI RS05535
gene id: 317577:DFI_RS05535
uniprot id: A0A221SV62
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.

317577:DFI RS11805
gene id: 317577:DFI_RS11805
uniprot id: A0A221SY92
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

317577:DFI RS01600
gene id: 317577:DFI_RS01600
uniprot id: A0A221STA7
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.
messages: Monomer.

317577:DFI RS11460
gene id: 317577:DFI_RS11460
uniprot id: A0A221SY03
names: Subcellular Location Annotation
messages: Membrane

317577:DFI RS07110
gene id: 317577:DFI_RS07110
uniprot id: A0A221SVX7
names: Similarity
messages: Belongs to the Skp family.

317577:DFI RS14155
gene id: 317577:DFI_RS14155
uniprot id: A0A221T0D6
names: Activity Regulation
names: Caution
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

317577:DFI RS04545
gene id: 317577:DFI_RS04545
uniprot id: A0A221SUQ6
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

317577:DFI RS16215
gene id: 317577:DFI_RS16215
uniprot id: A0A221T1C8
names: Similarity
messages: Belongs to the AHA1 family.

317577:DFI RS09405
gene id: 317577:DFI_RS09405
uniprot id: A0A221SX16
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

317577:DFI RS03960
gene id: 317577:DFI_RS03960
uniprot id: A0A221SUI7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmE/CycJ family.
messages: Cell membrane
messages: Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.

317577:DFI RS03815
gene id: 317577:DFI_RS03815
uniprot id: A0A221SUC5
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

317577:DFI RS12880
gene id: 317577:DFI_RS12880
uniprot id: A0A221SYT3
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.

317577:DFI RS10815
gene id: 317577:DFI_RS10815
uniprot id: A0A221SXQ6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
messages: This function is generally fulfilled by the C-terminal part of HisG, which is missing in some bacteria such as this one.

317577:DFI RS04565
gene id: 317577:DFI_RS04565
uniprot id: A0A221SUS4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

317577:DFI RS15170
gene id: 317577:DFI_RS15170
uniprot id: A0A221T1M5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

317577:DFI RS00100
gene id: 317577:DFI_RS00100
uniprot id: A0A221SZ36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uridine kinase family.
messages: Cytoplasm

317577:DFI RS14185
gene id: 317577:DFI_RS14185
uniprot id: A0A221T0A0
names: Similarity
messages: Belongs to the glycosyl hydrolase 42 family.

317577:DFI RS09990
gene id: 317577:DFI_RS09990
uniprot id: A0A221SXE7
names: Subcellular Location Annotation
messages: Membrane

317577:DFI RS00645
gene id: 317577:DFI_RS00645
uniprot id: A0A221SSU6
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

317577:DFI RS02190
gene id: 317577:DFI_RS02190
uniprot id: A0A221STJ7
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

317577:DFI RS00010
gene id: 317577:DFI_RS00010
uniprot id: A0A221SSI5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

317577:DFI RS05985
gene id: 317577:DFI_RS05985
uniprot id: A0A221SVF6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IPP isomerase type 2 family.
messages: Cytoplasm
messages: Homooctamer. Dimer of tetramers.
messages: Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

317577:DFI RS02165
gene id: 317577:DFI_RS02165
uniprot id: A0A221STK4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

317577:DFI RS04475
gene id: 317577:DFI_RS04475
uniprot id: A0A221SUR8
names: Function
names: Similarity
messages: Belongs to the catalase family. HPII subfamily.
messages: Serves to protect cells from the toxic effects of hydrogen peroxide.

317577:DFI RS06815
gene id: 317577:DFI_RS06815
uniprot id: A0A221SVU3
names: Similarity
messages: Belongs to the peptidase C40 family.

317577:DFI RS17510
gene id: 317577:DFI_RS17510
uniprot id: A0A221T250
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.

317577:DFI RS08170
gene id: 317577:DFI_RS08170
uniprot id: A0A221SWF1
names: Subcellular Location Annotation
messages: Membrane

317577:DFI RS09220
gene id: 317577:DFI_RS09220
uniprot id: A0A221SX41
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

317577:DFI RS10710
gene id: 317577:DFI_RS10710
uniprot id: A0A221SXP2
names: Similarity
messages: Belongs to the Nudix hydrolase family.

317577:DFI RS17400
gene id: 317577:DFI_RS17400
uniprot id: A0A221T230
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

317577:DFI RS01555
gene id: 317577:DFI_RS01555
uniprot id: A0A221STB2
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

317577:DFI RS11625
gene id: 317577:DFI_RS11625
uniprot id: A0A221SY30
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

317577:DFI RS09815
gene id: 317577:DFI_RS09815
uniprot id: A0A221SXC2
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

317577:DFI RS16070
gene id: 317577:DFI_RS16070
uniprot id: A0A221T1B9
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20 family.
messages: Binds 2 Zn(2+) ions per subunit.

317577:DFI RS09020
gene id: 317577:DFI_RS09020
uniprot id: A0A221SWW1
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

317577:DFI RS10450
gene id: 317577:DFI_RS10450
uniprot id: A0A221SXJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ro 60 kDa family.
messages: Cytoplasm

317577:DFI RS11875
gene id: 317577:DFI_RS11875
uniprot id: A0A221T026
names: Function
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

317577:DFI RS12670
gene id: 317577:DFI_RS12670
uniprot id: A0A221SYJ2
names: Similarity
messages: Belongs to the YciI family.

317577:DFI RS02955
gene id: 317577:DFI_RS02955
uniprot id: A0A221STZ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

317577:DFI RS10270
gene id: 317577:DFI_RS10270
uniprot id: A0A221SXI5
names: Similarity
messages: Belongs to the Nudix hydrolase family.

317577:DFI RS07195
gene id: 317577:DFI_RS07195
uniprot id: A0A221SZK0
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

317577:DFI RS11510
gene id: 317577:DFI_RS11510
uniprot id: A0A221SY08
names: Function
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.
messages: Catalyzes the ATP-dependent phosphorylation of fructose-l-phosphate to fructose-l,6-bisphosphate.

317577:DFI RS07505
gene id: 317577:DFI_RS07505
uniprot id: A0A221SW44
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably interacts with PlsX.

317577:DFI RS05155
gene id: 317577:DFI_RS05155
uniprot id: A0A221SV05
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

317577:DFI RS18760
gene id: 317577:DFI_RS18760
uniprot id: A0A221T2W9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

317577:DFI RS02150
gene id: 317577:DFI_RS02150
uniprot id: A0A221STK1
names: Subcellular Location Annotation
messages: Membrane

317577:DFI RS03310
gene id: 317577:DFI_RS03310
uniprot id: A0A221SU75
names: Similarity
messages: Belongs to the peptidase S9C family.

317577:DFI RS02210
gene id: 317577:DFI_RS02210
uniprot id: A0A221STL2
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

317577:DFI RS18075
gene id: 317577:DFI_RS18075
uniprot id: A0A221T2F4
names: Similarity
messages: Belongs to the asparagine synthetase family.

317577:DFI RS05190
gene id: 317577:DFI_RS05190
uniprot id: A0A221SV14
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.
messages: Cytoplasm
messages: Homodimer.

317577:DFI RS06335
gene id: 317577:DFI_RS06335
uniprot id: A0A221SVK2
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

317577:DFI RS03775
gene id: 317577:DFI_RS03775
uniprot id: A0A221SUD9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

317577:DFI RS18130
gene id: 317577:DFI_RS18130
uniprot id: A0A221T2G8
names: Subcellular Location Annotation
messages: Membrane

317577:DFI RS17495
gene id: 317577:DFI_RS17495
uniprot id: A0A221T291
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

317577:DFI RS09330
gene id: 317577:DFI_RS09330
uniprot id: A0A221SX02
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. Homocitrate synthase LYS20/LYS21 subfamily.

317577:DFI RS12000
gene id: 317577:DFI_RS12000
uniprot id: A0A221SYC9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: NDH-1 is composed of 15 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

317577:DFI RS08365
gene id: 317577:DFI_RS08365
uniprot id: A0A221SWJ7
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

317577:DFI RS01020
gene id: 317577:DFI_RS01020
uniprot id: A0A221ST11
names: Subcellular Location Annotation
messages: Membrane

317577:DFI RS15395
gene id: 317577:DFI_RS15395
uniprot id: A0A221T122
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

317577:DFI RS02575
gene id: 317577:DFI_RS02575
uniprot id: A0A221STR1
names: Caution
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

317577:DFI RS09675
gene id: 317577:DFI_RS09675
uniprot id: A0A221SX69
names: Similarity
messages: Belongs to the FBPase class 2 family.

317577:DFI RS06220
gene id: 317577:DFI_RS06220
uniprot id: A0A221SVI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

317577:DFI RS15235
gene id: 317577:DFI_RS15235
uniprot id: A0A221T0V9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

317577:DFI RS07015
gene id: 317577:DFI_RS07015
uniprot id: A0A221SVZ3
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

317577:DFI RS04975
gene id: 317577:DFI_RS04975
uniprot id: A0A221SUX7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

317577:DFI RS13440
gene id: 317577:DFI_RS13440
uniprot id: A0A221SZ21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

317577:DFI RS01405
gene id: 317577:DFI_RS01405
uniprot id: A0A221SZ68
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

317577:DFI RS17945
gene id: 317577:DFI_RS17945
uniprot id: A0A221T2C7
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

317577:DFI RS01550
gene id: 317577:DFI_RS01550
uniprot id: A0A221STA4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.

317577:DFI RS00755
gene id: 317577:DFI_RS00755
uniprot id: A0A221SSW1
names: Subcellular Location Annotation
messages: Membrane

317577:DFI RS00130
gene id: 317577:DFI_RS00130
uniprot id: A0A221SSL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

317577:DFI RS02710
gene id: 317577:DFI_RS02710
uniprot id: A0A221STV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

317577:DFI RS10515
gene id: 317577:DFI_RS10515
uniprot id: A0A221SXL3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Cu-Zn superoxide dismutase family.
messages: Binds 1 copper ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

317577:DFI RS02310
gene id: 317577:DFI_RS02310
uniprot id: A0A221STK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DcuA/DcuB transporter (TC 2.A.13.1) family.
messages: Cell inner membrane
messages: Membrane

317577:DFI RS02915
gene id: 317577:DFI_RS02915
uniprot id: A0A221STW4
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

317577:DFI RS12855
gene id: 317577:DFI_RS12855
uniprot id: A0A221SYR4
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

317577:DFI RS08760
gene id: 317577:DFI_RS08760
uniprot id: A0A221SWR2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 2 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

317577:DFI RS09305
gene id: 317577:DFI_RS09305
uniprot id: A0A221SWZ9
names: Similarity
messages: Belongs to the peptidase S8 family.

317577:DFI RS07785
gene id: 317577:DFI_RS07785
uniprot id: A0A221SWD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

317577:DFI RS07610
gene id: 317577:DFI_RS07610
uniprot id: A0A221SW63
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

317577:DFI RS17640
gene id: 317577:DFI_RS17640
uniprot id: A0A221T267
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

317577:DFI RS00365
gene id: 317577:DFI_RS00365
uniprot id: A0A221SSP1
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

317577:DFI RS14615
gene id: 317577:DFI_RS14615
uniprot id: A0A221T0L1
names: Similarity
messages: Belongs to the peptidase M29 family.

317577:DFI RS03585
gene id: 317577:DFI_RS03585
uniprot id: A0A221SUB9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

317577:DFI RS08370
gene id: 317577:DFI_RS08370
uniprot id: A0A221SWJ1
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Dimer of large and small chains.

317577:DFI RS10840
gene id: 317577:DFI_RS10840
uniprot id: A0A221SXR3
names: Subcellular Location Annotation
messages: Membrane

317577:DFI RS02690
gene id: 317577:DFI_RS02690
uniprot id: A0A221STW2
names: Similarity
messages: Belongs to the thioredoxin family.

317577:DFI RS01410
gene id: 317577:DFI_RS01410
uniprot id: A0A221ST85
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

317577:DFI RS05820
gene id: 317577:DFI_RS05820
uniprot id: A0A221SVD1
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

317577:DFI RS08770
gene id: 317577:DFI_RS08770
uniprot id: A0A221SWQ3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

317577:DFI RS03770
gene id: 317577:DFI_RS03770
uniprot id: A0A221SUG0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmG family. TrmFO subfamily.
messages: Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
messages: Cytoplasm

317577:DFI RS00775
gene id: 317577:DFI_RS00775
uniprot id: A0A221SSV6
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit.

317577:DFI RS12060
gene id: 317577:DFI_RS12060
uniprot id: A0A221SYD9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

317577:DFI RS04150
gene id: 317577:DFI_RS04150
uniprot id: A0A221SUJ6
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

317577:DFI RS09740
gene id: 317577:DFI_RS09740
uniprot id: A0A221SX74
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

317577:DFI RS09995
gene id: 317577:DFI_RS09995
uniprot id: A0A221SXD0
names: Subcellular Location Annotation
messages: Membrane

317577:DFI RS12950
gene id: 317577:DFI_RS12950
uniprot id: A0A221SYP2
names: Similarity
messages: Belongs to the peptidase U62 family.

317577:DFI RS03280
gene id: 317577:DFI_RS03280
uniprot id: A0A221SU65
names: Similarity
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.

317577:DFI RS13420
gene id: 317577:DFI_RS13420
uniprot id: A0A221SZ23
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

317577:DFI RS05910
gene id: 317577:DFI_RS05910
uniprot id: A0A221SZH7
names: Caution
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

317577:DFI RS16390
gene id: 317577:DFI_RS16390
uniprot id: A0A221T1G2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. TCR/Tet family.
messages: Membrane

317577:DFI RS17230
gene id: 317577:DFI_RS17230
uniprot id: A0A221T246
names: Similarity
messages: Belongs to the ParB family.

317577:DFI RS13490
gene id: 317577:DFI_RS13490
uniprot id: A0A221SYZ8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DtxR/MntR family.
messages: Cytoplasm
messages: Homodimer.

317577:DFI RS03910
gene id: 317577:DFI_RS03910
uniprot id: A0A221SUF9
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

317577:DFI RS00555
gene id: 317577:DFI_RS00555
uniprot id: A0A221SSS1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

317577:DFI RS17090
gene id: 317577:DFI_RS17090
uniprot id: A0A221T213
names: Function
names: Similarity
messages: Belongs to the APS kinase family.
messages: Catalyzes the synthesis of activated sulfate.

317577:DFI RS09235
gene id: 317577:DFI_RS09235
uniprot id: A0A221SWY9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

317577:DFI RS13915
gene id: 317577:DFI_RS13915
uniprot id: A0A221T071
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

317577:DFI RS11650
gene id: 317577:DFI_RS11650
uniprot id: A0A221SY65
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

317577:DFI RS04425
gene id: 317577:DFI_RS04425
uniprot id: A0A221SUN6
names: Similarity
messages: Belongs to the manganese catalase family.

317577:DFI RS08270
gene id: 317577:DFI_RS08270
uniprot id: A0A221SWL6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

317577:DFI RS12955
gene id: 317577:DFI_RS12955
uniprot id: A0A221SYR1
names: Similarity
messages: Belongs to the peptidase U62 family.

317577:DFI RS01390
gene id: 317577:DFI_RS01390
uniprot id: A0A221ST76
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

317577:DFI RS02980
gene id: 317577:DFI_RS02980
uniprot id: A0A221STY1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

317577:DFI RS12190
gene id: 317577:DFI_RS12190
uniprot id: A0A221SYD6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

317577:DFI RS10635
gene id: 317577:DFI_RS10635
uniprot id: A0A221SXN2
names: Function
names: Similarity
messages: Belongs to the SELO family.
messages: Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).

317577:DFI RS01155
gene id: 317577:DFI_RS01155
uniprot id: A0A221ST39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

317577:DFI RS13000
gene id: 317577:DFI_RS13000
uniprot id: A0A221SYQ2
names: Subcellular Location Annotation
messages: Membrane

317577:DFI RS15230
gene id: 317577:DFI_RS15230
uniprot id: A0A221T0V8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

317577:DFI RS06280
gene id: 317577:DFI_RS06280
uniprot id: A0A221SVM6
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

317577:DFI RS06140
gene id: 317577:DFI_RS06140
uniprot id: A0A221SVG6
names: Subcellular Location Annotation
messages: Membrane

317577:DFI RS00110
gene id: 317577:DFI_RS00110
uniprot id: A0A221SSK0
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

317577:DFI RS19440
gene id: 317577:DFI_RS19440
uniprot id: A0A221T3A4
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

317577:DFI RS09505
gene id: 317577:DFI_RS09505
uniprot id: A0A221SX51
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

317577:DFI RS13615
gene id: 317577:DFI_RS13615
uniprot id: A0A221SZ08
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

317577:DFI RS09445
gene id: 317577:DFI_RS09445
uniprot id: A0A221SX33
names: Subcellular Location Annotation
messages: Cytoplasm

317577:DFI RS11180
gene id: 317577:DFI_RS11180
uniprot id: A0A221SXW0
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

317577:DFI RS00925
gene id: 317577:DFI_RS00925
uniprot id: A0A221SSZ1
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

317577:DFI RS07350
gene id: 317577:DFI_RS07350
uniprot id: A0A221SW18
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

317577:DFI RS11750
gene id: 317577:DFI_RS11750
uniprot id: A0A221SY81
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

317577:DFI RS02315
gene id: 317577:DFI_RS02315
uniprot id: A0A221STN6
names: Similarity
messages: Belongs to the class-II fumarase/aspartase family. Aspartase subfamily.

317577:DFI RS13590
gene id: 317577:DFI_RS13590
uniprot id: A0A221SZ18
names: Similarity
messages: Belongs to the TrpF family.

317577:DFI RS01845
gene id: 317577:DFI_RS01845
uniprot id: A0A221STD0
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

317577:DFI RS11105
gene id: 317577:DFI_RS11105
uniprot id: A0A221SY02
names: Similarity
messages: Belongs to the peptidase S1C family.

317577:DFI RS12895
gene id: 317577:DFI_RS12895
uniprot id: A0A221SYP9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

317577:DFI RS02030
gene id: 317577:DFI_RS02030
uniprot id: A0A221STF9
names: Function
names: Similarity
messages: Belongs to the CobT family.
messages: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).

317577:DFI RS06365
gene id: 317577:DFI_RS06365
uniprot id: A0A221SVM1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

317577:DFI RS08665
gene id: 317577:DFI_RS08665
uniprot id: A0A221SWU6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

317577:DFI RS05610
gene id: 317577:DFI_RS05610
uniprot id: A0A221SV91
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

317577:DFI RS18355
gene id: 317577:DFI_RS18355
uniprot id: A0A221T2N9
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

317577:DFI RS00025
gene id: 317577:DFI_RS00025
uniprot id: A0A221SSI9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

317577:DFI RS05545
gene id: 317577:DFI_RS05545
uniprot id: A0A221SV54
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protoporphyrinogen/coproporphyrinogen oxidase family. Coproporphyrinogen III oxidase subfamily.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the oxidation of coproporphyrinogen III to coproporphyrin III.

317577:DFI RS09625
gene id: 317577:DFI_RS09625
uniprot id: A0A221SX59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetokinase family.
messages: Cytoplasm

317577:DFI RS08965
gene id: 317577:DFI_RS08965
uniprot id: A0A221SWU5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

317577:DFI RS02000
gene id: 317577:DFI_RS02000
uniprot id: A0A221STG9
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

317577:DFI RS09570
gene id: 317577:DFI_RS09570
uniprot id: A0A221SX45
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

317577:DFI RS07460
gene id: 317577:DFI_RS07460
uniprot id: A0A221SW73
names: Subcellular Location Annotation
messages: Membrane

317577:DFI RS07425
gene id: 317577:DFI_RS07425
uniprot id: A0A221SW31
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

317577:DFI RS05165
gene id: 317577:DFI_RS05165
uniprot id: A0A221SV15
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

317577:DFI RS17860
gene id: 317577:DFI_RS17860
uniprot id: A0A221T2B3
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

317577:DFI RS03185
gene id: 317577:DFI_RS03185
uniprot id: A0A221SU53
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

317577:DFI RS04685
gene id: 317577:DFI_RS04685
uniprot id: A0A221SUW5
names: Subcellular Location Annotation
messages: Membrane

317577:DFI RS16015
gene id: 317577:DFI_RS16015
uniprot id: A0A221T1B0
names: Function
names: Similarity
messages: Belongs to the NanE family.
messages: Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P).

317577:DFI RS11365
gene id: 317577:DFI_RS11365
uniprot id: A0A221SY41
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

317577:DFI RS06920
gene id: 317577:DFI_RS06920
uniprot id: A0A221SZI8
names: Similarity
messages: Belongs to the aspartokinase family.

317577:DFI RS17590
gene id: 317577:DFI_RS17590
uniprot id: A0A221T261
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

317577:DFI RS12700
gene id: 317577:DFI_RS12700
uniprot id: A0A221SYK3
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Periplasm

317577:DFI RS08280
gene id: 317577:DFI_RS08280
uniprot id: A0A221SWH7
names: Similarity
messages: Belongs to the leucine-binding protein family.

317577:DFI RS09135
gene id: 317577:DFI_RS09135
uniprot id: A0A221SX06
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

317577:DFI RS02400
gene id: 317577:DFI_RS02400
uniprot id: A0A221STP9
names: Function
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.
messages: Catalyzes the biosynthesis of agmatine from arginine.