313596:RB2501 RS06990
gene id: 313596:RB2501_RS06990
uniprot id: A4CM51
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

313596:RB2501 RS15460
gene id: 313596:RB2501_RS15460
uniprot id: A4CPQ8
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

313596:RB2501 RS05340
gene id: 313596:RB2501_RS05340
uniprot id: A4CJ72
names: Function
names: Similarity
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.

313596:RB2501 RS01310
gene id: 313596:RB2501_RS01310
uniprot id: A4CGU5
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

313596:RB2501 RS09500
gene id: 313596:RB2501_RS09500
uniprot id: A4CK60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

313596:RB2501 RS13925
gene id: 313596:RB2501_RS13925
uniprot id: A4CPX7
names: Similarity
messages: Belongs to the IlvD/Edd family.

313596:RB2501 RS09970
gene id: 313596:RB2501_RS09970
uniprot id: A4CKG0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

313596:RB2501 RS07950
gene id: 313596:RB2501_RS07950
uniprot id: A4CMP7
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

313596:RB2501 RS13590
gene id: 313596:RB2501_RS13590
uniprot id: A4CP24
names: Subcellular Location Annotation
messages: Membrane

313596:RB2501 RS15355
gene id: 313596:RB2501_RS15355
uniprot id: A4CPN7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

313596:RB2501 RS10790
gene id: 313596:RB2501_RS10790
uniprot id: A4CKY5
names: Subcellular Location Annotation
messages: Membrane

313596:RB2501 RS15050
gene id: 313596:RB2501_RS15050
uniprot id: A4CPH2
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

313596:RB2501 RS10880
gene id: 313596:RB2501_RS10880
uniprot id: A4CL03
names: Subcellular Location Annotation
messages: Membrane

313596:RB2501 RS09395
gene id: 313596:RB2501_RS09395
uniprot id: A4CK40
names: Similarity
messages: Belongs to the ClpA/ClpB family.

313596:RB2501 RS04875
gene id: 313596:RB2501_RS04875
uniprot id: A4CIX8
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

313596:RB2501 RS08605
gene id: 313596:RB2501_RS08605
uniprot id: A4CN29
names: Subcellular Location Annotation
messages: Membrane

313596:RB2501 RS01705
gene id: 313596:RB2501_RS01705
uniprot id: A4CH23
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

313596:RB2501 RS14725
gene id: 313596:RB2501_RS14725
uniprot id: A4CPA4
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain.

313596:RB2501 RS10025
gene id: 313596:RB2501_RS10025
uniprot id: A4CKH0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

313596:RB2501 RS09740
gene id: 313596:RB2501_RS09740
uniprot id: A4CKB0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inositol monophosphatase superfamily. CysQ family.
messages: Cell inner membrane
messages: Converts adenosine-3',5'-bisphosphate (PAP) to AMP.

313596:RB2501 RS06565
gene id: 313596:RB2501_RS06565
uniprot id: A4CJW9
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

313596:RB2501 RS07370
gene id: 313596:RB2501_RS07370
uniprot id: A4CMC6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

313596:RB2501 RS11910
gene id: 313596:RB2501_RS11910
uniprot id: A4CLM2
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

313596:RB2501 RS06305
gene id: 313596:RB2501_RS06305
uniprot id: A4CJR6
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

313596:RB2501 RS12910
gene id: 313596:RB2501_RS12910
uniprot id: A4CNN6
names: Cofactor
messages: Binds 1 zinc ion per subunit.

313596:RB2501 RS00215
gene id: 313596:RB2501_RS00215
uniprot id: A4CG73
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

313596:RB2501 RS05165
gene id: 313596:RB2501_RS05165
uniprot id: A4CJ37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

313596:RB2501 RS00810
gene id: 313596:RB2501_RS00810
uniprot id: A4CGJ3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urocanase family.
messages: Binds 1 NAD(+) per subunit.
messages: Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

313596:RB2501 RS08100
gene id: 313596:RB2501_RS08100
uniprot id: A4CMS6
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

313596:RB2501 RS12665
gene id: 313596:RB2501_RS12665
uniprot id: A4CNI1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

313596:RB2501 RS08215
gene id: 313596:RB2501_RS08215
uniprot id: A4CMV1
names: Similarity
messages: Belongs to the SIS family. GutQ/KpsF subfamily.

313596:RB2501 RS07935
gene id: 313596:RB2501_RS07935
uniprot id: A4CMP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YejK family.
messages: nucleoid

313596:RB2501 RS00415
gene id: 313596:RB2501_RS00415
uniprot id: A4CGB6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

313596:RB2501 RS10065
gene id: 313596:RB2501_RS10065
uniprot id: A4CKH7
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

313596:RB2501 RS06125
gene id: 313596:RB2501_RS06125
uniprot id: A4CJN1
names: Similarity
messages: Belongs to the glycosyl hydrolase 51 family.

313596:RB2501 RS08010
gene id: 313596:RB2501_RS08010
uniprot id: A4CMQ8
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

313596:RB2501 RS06900
gene id: 313596:RB2501_RS06900
uniprot id: A4CM34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

313596:RB2501 RS01220
gene id: 313596:RB2501_RS01220
uniprot id: A4CGS7
names: Similarity
messages: Belongs to the FGGY kinase family.

313596:RB2501 RS05490
gene id: 313596:RB2501_RS05490
uniprot id: A4CJA4
names: Subcellular Location Annotation
messages: Membrane

313596:RB2501 RS01225
gene id: 313596:RB2501_RS01225
uniprot id: A4CGS8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the xylose isomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.

313596:RB2501 RS12595
gene id: 313596:RB2501_RS12595
uniprot id: A4CNG7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

313596:RB2501 RS10525
gene id: 313596:RB2501_RS10525
uniprot id: A4CKS8
names: Subcellular Location Annotation
messages: Cytoplasm

313596:RB2501 RS12200
gene id: 313596:RB2501_RS12200
uniprot id: A4CLT2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

313596:RB2501 RS04710
gene id: 313596:RB2501_RS04710
uniprot id: A4CIU5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

313596:RB2501 RS06530
gene id: 313596:RB2501_RS06530
uniprot id: A4CJW1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell inner membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

313596:RB2501 RS04360
gene id: 313596:RB2501_RS04360
uniprot id: A4CIM3
names: Similarity
messages: Belongs to the ArsC family.

313596:RB2501 RS12735
gene id: 313596:RB2501_RS12735
uniprot id: A4CNJ7
names: Similarity
messages: Belongs to the CarB family.

313596:RB2501 RS04730
gene id: 313596:RB2501_RS04730
uniprot id: A4CIU9
names: Similarity
messages: Belongs to the UPF0045 family.

313596:RB2501 RS10060
gene id: 313596:RB2501_RS10060
uniprot id: A4CKH6
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

313596:RB2501 RS14625
gene id: 313596:RB2501_RS14625
uniprot id: A4CP82
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

313596:RB2501 RS05470
gene id: 313596:RB2501_RS05470
uniprot id: A4CJA0
names: Similarity
messages: Belongs to the peptidase S41A family.

313596:RB2501 RS12695
gene id: 313596:RB2501_RS12695
uniprot id: A4CNI8
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

313596:RB2501 RS14785
gene id: 313596:RB2501_RS14785
uniprot id: A4CPB7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

313596:RB2501 RS06730
gene id: 313596:RB2501_RS06730
uniprot id: A4CM00
names: Subcellular Location Annotation
messages: Membrane

313596:RB2501 RS09095
gene id: 313596:RB2501_RS09095
uniprot id: A4CND5
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

313596:RB2501 RS11035
gene id: 313596:RB2501_RS11035
uniprot id: A4CL34
names: Similarity
messages: Belongs to the SUI1 family.

313596:RB2501 RS07830
gene id: 313596:RB2501_RS07830
uniprot id: A4CMM1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M20B family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Cleaves the N-terminal amino acid of tripeptides.
messages: Cytoplasm

313596:RB2501 RS08935
gene id: 313596:RB2501_RS08935
uniprot id: A4CNA2
names: Similarity
messages: Belongs to the group II decarboxylase family.

313596:RB2501 RS12420
gene id: 313596:RB2501_RS12420
uniprot id: A4CLX7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

313596:RB2501 RS04650
gene id: 313596:RB2501_RS04650
uniprot id: A4CIT3
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

313596:RB2501 RS12390
gene id: 313596:RB2501_RS12390
uniprot id: A4CLX1
names: Function
names: Similarity
messages: Belongs to the transglycosylase MltG family.
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

313596:RB2501 RS09370
gene id: 313596:RB2501_RS09370
uniprot id: A4CK35
names: Similarity
messages: Belongs to the threonine synthase family.

313596:RB2501 RS15465
gene id: 313596:RB2501_RS15465
uniprot id: A4CPQ9
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

313596:RB2501 RS06645
gene id: 313596:RB2501_RS06645
uniprot id: A4CJY6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

313596:RB2501 RS05865
gene id: 313596:RB2501_RS05865
uniprot id: A4CJI2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

313596:RB2501 RS05430
gene id: 313596:RB2501_RS05430
uniprot id: A4CJ92
names: Similarity
messages: Belongs to the HMG-CoA reductase family.

313596:RB2501 RS09990
gene id: 313596:RB2501_RS09990
uniprot id: A4CKG4
names: Similarity
messages: Belongs to the SAM hydrolase / SAM-dependent halogenase family.

313596:RB2501 RS11205
gene id: 313596:RB2501_RS11205
uniprot id: A4CL69
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family. TreS subfamily.

313596:RB2501 RS12835
gene id: 313596:RB2501_RS12835
uniprot id: A4CNM0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: In the N-terminal section; belongs to the FGAMS family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.

313596:RB2501 RS02710
gene id: 313596:RB2501_RS02710
uniprot id: A4CHM9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

313596:RB2501 RS01540
gene id: 313596:RB2501_RS01540
uniprot id: A4CGZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

313596:RB2501 RS07010
gene id: 313596:RB2501_RS07010
uniprot id: A4CM55
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell inner membrane

313596:RB2501 RS04300
gene id: 313596:RB2501_RS04300
uniprot id: A4CIL1
names: Subcellular Location Annotation
messages: Membrane

313596:RB2501 RS15325
gene id: 313596:RB2501_RS15325
uniprot id: A4CPM9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

313596:RB2501 RS12550
gene id: 313596:RB2501_RS12550
uniprot id: A4CNF8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

313596:RB2501 RS00975
gene id: 313596:RB2501_RS00975
uniprot id: A4CGM6
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

313596:RB2501 RS08850
gene id: 313596:RB2501_RS08850
uniprot id: A4CN84
names: Similarity
messages: Belongs to the UPF0047 family.

313596:RB2501 RS06195
gene id: 313596:RB2501_RS06195
uniprot id: A4CJP4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

313596:RB2501 RS06230
gene id: 313596:RB2501_RS06230
uniprot id: A4CJQ1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

313596:RB2501 RS08055
gene id: 313596:RB2501_RS08055
uniprot id: A4CMR7
names: Subcellular Location Annotation
messages: Membrane

313596:RB2501 RS00775
gene id: 313596:RB2501_RS00775
uniprot id: A4CGI6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RuvC family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.

313596:RB2501 RS05130
gene id: 313596:RB2501_RS05130
uniprot id: A4CJ30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

313596:RB2501 RS11415
gene id: 313596:RB2501_RS11415
uniprot id: A4CLB6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

313596:RB2501 RS04900
gene id: 313596:RB2501_RS04900
uniprot id: A4CIY4
names: Similarity
messages: Belongs to the AlaDH/PNT family.

313596:RB2501 RS08255
gene id: 313596:RB2501_RS08255
uniprot id: A4CMW0
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.

313596:RB2501 RS09365
gene id: 313596:RB2501_RS09365
uniprot id: A4CK34
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

313596:RB2501 RS03295
gene id: 313596:RB2501_RS03295
uniprot id: A4CI06
names: Subcellular Location Annotation
messages: Membrane

313596:RB2501 RS10795
gene id: 313596:RB2501_RS10795
uniprot id: A4CKY6
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

313596:RB2501 RS00595
gene id: 313596:RB2501_RS00595
uniprot id: A4CGF0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

313596:RB2501 RS13005
gene id: 313596:RB2501_RS13005
uniprot id: A4CNQ5
names: Similarity
messages: Belongs to the DEAD box helicase family.

313596:RB2501 RS09930
gene id: 313596:RB2501_RS09930
uniprot id: A4CKF0
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.

313596:RB2501 RS14720
gene id: 313596:RB2501_RS14720
uniprot id: A4CPA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

313596:RB2501 RS09235
gene id: 313596:RB2501_RS09235
uniprot id: A4CK08
names: Subcellular Location Annotation
messages: Membrane

313596:RB2501 RS04550
gene id: 313596:RB2501_RS04550
uniprot id: A4CIR2
names: Subcellular Location Annotation
messages: Membrane

313596:RB2501 RS14840
gene id: 313596:RB2501_RS14840
uniprot id: A4CPC8
names: Function
names: Similarity
messages: Belongs to the aromatic-ring hydroxylase family. KMO subfamily.
messages: Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.

313596:RB2501 RS00580
gene id: 313596:RB2501_RS00580
uniprot id: A4CGE7
names: Similarity
messages: Belongs to the asparaginase 1 family.

313596:RB2501 RS15090
gene id: 313596:RB2501_RS15090
uniprot id: A4CPI0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

313596:RB2501 RS04580
gene id: 313596:RB2501_RS04580
uniprot id: A4CIR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

313596:RB2501 RS14260
gene id: 313596:RB2501_RS14260
uniprot id: A4CQ47
names: Similarity
messages: Belongs to the CinA family.

313596:RB2501 RS14960
gene id: 313596:RB2501_RS14960
uniprot id: A4CPF2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

313596:RB2501 RS08390
gene id: 313596:RB2501_RS08390
uniprot id: A4CMY6
names: Similarity
messages: Belongs to the universal stress protein A family.

313596:RB2501 RS09225
gene id: 313596:RB2501_RS09225
uniprot id: A4CK06
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

313596:RB2501 RS08480
gene id: 313596:RB2501_RS08480
uniprot id: A4CN05
names: Similarity
messages: Belongs to the peptidase S58 family.

313596:RB2501 RS02230
gene id: 313596:RB2501_RS02230
uniprot id: A4CHD0
names: Subcellular Location Annotation
messages: Membrane

313596:RB2501 RS04450
gene id: 313596:RB2501_RS04450
uniprot id: A4CIP2
names: Subcellular Location Annotation
messages: Membrane

313596:RB2501 RS09675
gene id: 313596:RB2501_RS09675
uniprot id: A4CK97
names: Similarity
messages: Belongs to the RutC family.

313596:RB2501 RS10940
gene id: 313596:RB2501_RS10940
uniprot id: A4CL15
names: Similarity
messages: Belongs to the phosphohexose mutase family.

313596:RB2501 RS12235
gene id: 313596:RB2501_RS12235
uniprot id: A4CLU0
names: Subcellular Location Annotation
messages: Membrane

313596:RB2501 RS03580
gene id: 313596:RB2501_RS03580
uniprot id: A4CI65
names: Similarity
messages: Belongs to the peptidase S8 family.

313596:RB2501 RS13955
gene id: 313596:RB2501_RS13955
uniprot id: A4CPY4
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A lyase-type mechanism (elimination/hydration) is suggested for the cleavage of the lactyl ether bond of MurNAc 6-phosphate, with the formation of an alpha,beta-unsaturated aldehyde intermediate with (E)-stereochemistry, followed by the syn addition of water to give product.
messages: Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
messages: Homodimer.
messages: Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate.

313596:RB2501 RS08985
gene id: 313596:RB2501_RS08985
uniprot id: A4CNB3
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

313596:RB2501 RS14465
gene id: 313596:RB2501_RS14465
uniprot id: A4CQ91
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

313596:RB2501 RS03575
gene id: 313596:RB2501_RS03575
uniprot id: A4CI64
names: Cofactor
messages: Binds 1 zinc ion per subunit.

313596:RB2501 RS15370
gene id: 313596:RB2501_RS15370
uniprot id: A4CPP0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

313596:RB2501 RS15040
gene id: 313596:RB2501_RS15040
uniprot id: A4CPH0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

313596:RB2501 RS13505
gene id: 313596:RB2501_RS13505
uniprot id: A4CP09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Cell membrane
messages: Membrane

313596:RB2501 RS04070
gene id: 313596:RB2501_RS04070
uniprot id: A4CIG4
names: Similarity
messages: Belongs to the universal stress protein A family.

313596:RB2501 RS04950
gene id: 313596:RB2501_RS04950
uniprot id: A4CIZ4
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

313596:RB2501 RS08870
gene id: 313596:RB2501_RS08870
uniprot id: A4CN88
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

313596:RB2501 RS09140
gene id: 313596:RB2501_RS09140
uniprot id: A4CNE5
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

313596:RB2501 RS07605
gene id: 313596:RB2501_RS07605
uniprot id: A4CMH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

313596:RB2501 RS07710
gene id: 313596:RB2501_RS07710
uniprot id: A4CMJ5
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

313596:RB2501 RS15300
gene id: 313596:RB2501_RS15300
uniprot id: A4CPM4
names: Function
names: Similarity
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

313596:RB2501 RS00425
gene id: 313596:RB2501_RS00425
uniprot id: A4CGB8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

313596:RB2501 RS08915
gene id: 313596:RB2501_RS08915
uniprot id: A4CN98
names: Subcellular Location Annotation
messages: Membrane

313596:RB2501 RS14035
gene id: 313596:RB2501_RS14035
uniprot id: A4CQ00
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

313596:RB2501 RS01495
gene id: 313596:RB2501_RS01495
uniprot id: A4CGY2
names: Subcellular Location Annotation
messages: Membrane

313596:RB2501 RS05565
gene id: 313596:RB2501_RS05565
uniprot id: A4CJB9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

313596:RB2501 RS14970
gene id: 313596:RB2501_RS14970
uniprot id: A4CPF4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

313596:RB2501 RS00295
gene id: 313596:RB2501_RS00295
uniprot id: A4CG90
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane
messages: Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins.

313596:RB2501 RS11460
gene id: 313596:RB2501_RS11460
uniprot id: A4CLC5
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

313596:RB2501 RS13200
gene id: 313596:RB2501_RS13200
uniprot id: A4CNU6
names: Cofactor
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.

313596:RB2501 RS00275
gene id: 313596:RB2501_RS00275
uniprot id: A4CG86
names: Subcellular Location Annotation
messages: Membrane

313596:RB2501 RS00675
gene id: 313596:RB2501_RS00675
uniprot id: A4CGG7
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family.

313596:RB2501 RS03625
gene id: 313596:RB2501_RS03625
uniprot id: A4CI75
names: Subcellular Location Annotation
messages: Membrane

313596:RB2501 RS14485
gene id: 313596:RB2501_RS14485
uniprot id: A4CQ95
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

313596:RB2501 RS07750
gene id: 313596:RB2501_RS07750
uniprot id: A4CMK3
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

313596:RB2501 RS06700
gene id: 313596:RB2501_RS06700
uniprot id: A4CLZ4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

313596:RB2501 RS14995
gene id: 313596:RB2501_RS14995
uniprot id: A4CPF9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Membrane
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

313596:RB2501 RS09890
gene id: 313596:RB2501_RS09890
uniprot id: A4CKE2
names: Similarity
messages: Belongs to the polysaccharide synthase family.

313596:RB2501 RS02685
gene id: 313596:RB2501_RS02685
uniprot id: A4CHM4
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

313596:RB2501 RS15215
gene id: 313596:RB2501_RS15215
uniprot id: A4CPK6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell inner membrane
messages: Self-interacts. Interacts with FtsZ.

313596:RB2501 RS10985
gene id: 313596:RB2501_RS10985
uniprot id: A4CL24
names: Subcellular Location Annotation
messages: Membrane

313596:RB2501 RS12080
gene id: 313596:RB2501_RS12080
uniprot id: A4CLQ8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

313596:RB2501 RS02620
gene id: 313596:RB2501_RS02620
uniprot id: A4CHL1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

313596:RB2501 RS11685
gene id: 313596:RB2501_RS11685
uniprot id: A4CLH3
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

313596:RB2501 RS14080
gene id: 313596:RB2501_RS14080
uniprot id: A4CQ09
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

313596:RB2501 RS12370
gene id: 313596:RB2501_RS12370
uniprot id: A4CLW7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

313596:RB2501 RS01610
gene id: 313596:RB2501_RS01610
uniprot id: A4CH04
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

313596:RB2501 RS15435
gene id: 313596:RB2501_RS15435
uniprot id: A4CPQ3
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

313596:RB2501 RS00790
gene id: 313596:RB2501_RS00790
uniprot id: A4CGI9
names: Cofactor
names: Similarity
messages: Belongs to the nitroreductase family.
messages: Binds 1 FMN per subunit.

313596:RB2501 RS03985
gene id: 313596:RB2501_RS03985
uniprot id: A4CIE7
names: Similarity
messages: Belongs to the peptidase S9A family.

313596:RB2501 RS01680
gene id: 313596:RB2501_RS01680
uniprot id: A4CH18
names: Subcellular Location Annotation
messages: Membrane

313596:RB2501 RS05620
gene id: 313596:RB2501_RS05620
uniprot id: A4CJD0
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

313596:RB2501 RS03970
gene id: 313596:RB2501_RS03970
uniprot id: A4CIE4
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

313596:RB2501 RS02490
gene id: 313596:RB2501_RS02490
uniprot id: A4CHI5
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

313596:RB2501 RS14610
gene id: 313596:RB2501_RS14610
uniprot id: A4CP79
names: Similarity
messages: Belongs to the TrpC family.

313596:RB2501 RS14685
gene id: 313596:RB2501_RS14685
uniprot id: A4CP96
names: Similarity
messages: Belongs to the Nudix hydrolase family.

313596:RB2501 RS01775
gene id: 313596:RB2501_RS01775
uniprot id: A4CH37
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

313596:RB2501 RS05535
gene id: 313596:RB2501_RS05535
uniprot id: A4CJB3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Membrane

313596:RB2501 RS11015
gene id: 313596:RB2501_RS11015
uniprot id: A4CL30
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

313596:RB2501 RS04375
gene id: 313596:RB2501_RS04375
uniprot id: A4CIM6
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

313596:RB2501 RS00845
gene id: 313596:RB2501_RS00845
uniprot id: A4CGK1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Binds 1 copper ion per subunit, denoted as copper B.
messages: Binds 2 heme groups per subunit, denoted as high- and low-spin.
messages: Membrane

313596:RB2501 RS13330
gene id: 313596:RB2501_RS13330
uniprot id: A4CNX3
names: Similarity
messages: Belongs to the SusD family.

313596:RB2501 RS03425
gene id: 313596:RB2501_RS03425
uniprot id: A4CI34
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

313596:RB2501 RS04045
gene id: 313596:RB2501_RS04045
uniprot id: A4CIF9
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

313596:RB2501 RS11935
gene id: 313596:RB2501_RS11935
uniprot id: A4CLM8
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

313596:RB2501 RS03930
gene id: 313596:RB2501_RS03930
uniprot id: A4CID6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

313596:RB2501 RS12575
gene id: 313596:RB2501_RS12575
uniprot id: A4CNG3
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

313596:RB2501 RS12410
gene id: 313596:RB2501_RS12410
uniprot id: A4CLX5
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

313596:RB2501 RS12215
gene id: 313596:RB2501_RS12215
uniprot id: A4CLT6
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

313596:RB2501 RS05440
gene id: 313596:RB2501_RS05440
uniprot id: A4CJ94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane

313596:RB2501 RS00285
gene id: 313596:RB2501_RS00285
uniprot id: A4CG88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

313596:RB2501 RS00625
gene id: 313596:RB2501_RS00625
uniprot id: A4CGF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

313596:RB2501 RS15635
gene id: 313596:RB2501_RS15635
uniprot id: A4CPU3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

313596:RB2501 RS01660
gene id: 313596:RB2501_RS01660
uniprot id: A4CH14
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

313596:RB2501 RS00245
gene id: 313596:RB2501_RS00245
uniprot id: A4CG79
names: Subcellular Location Annotation
messages: Membrane

313596:RB2501 RS12870
gene id: 313596:RB2501_RS12870
uniprot id: A4CNM8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

313596:RB2501 RS12645
gene id: 313596:RB2501_RS12645
uniprot id: A4CNH7
names: Function
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
messages: Catalyzes two reactions in de novo purine nucleotide biosynthesis. Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate.

313596:RB2501 RS11510
gene id: 313596:RB2501_RS11510
uniprot id: A4CLD5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

313596:RB2501 RS06535
gene id: 313596:RB2501_RS06535
uniprot id: A4CJW2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

313596:RB2501 RS14180
gene id: 313596:RB2501_RS14180
uniprot id: A4CQ31
names: Similarity
messages: Belongs to the Fur family.

313596:RB2501 RS07815
gene id: 313596:RB2501_RS07815
uniprot id: A4CML8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

313596:RB2501 RS03995
gene id: 313596:RB2501_RS03995
uniprot id: A4CIE9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell inner membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

313596:RB2501 RS15570
gene id: 313596:RB2501_RS15570
uniprot id: A4CPT0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

313596:RB2501 RS14660
gene id: 313596:RB2501_RS14660
uniprot id: A4CP91
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

313596:RB2501 RS11380
gene id: 313596:RB2501_RS11380
uniprot id: A4CLA9
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

313596:RB2501 RS15480
gene id: 313596:RB2501_RS15480
uniprot id: A4CPR2
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

313596:RB2501 RS00930
gene id: 313596:RB2501_RS00930
uniprot id: A4CGL8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

313596:RB2501 RS00885
gene id: 313596:RB2501_RS00885
uniprot id: A4CGK9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Monomer.

313596:RB2501 RS06325
gene id: 313596:RB2501_RS06325
uniprot id: A4CJS0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

313596:RB2501 RS07020
gene id: 313596:RB2501_RS07020
uniprot id: A4CM57
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

313596:RB2501 RS03640
gene id: 313596:RB2501_RS03640
uniprot id: A4CI78
names: Subcellular Location Annotation
messages: Membrane

313596:RB2501 RS11480
gene id: 313596:RB2501_RS11480
uniprot id: A4CLC9
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Feedback inhibited by histidine.

313596:RB2501 RS02235
gene id: 313596:RB2501_RS02235
uniprot id: A4CHD1
names: Similarity
messages: Belongs to the DtxR/MntR family.

313596:RB2501 RS12360
gene id: 313596:RB2501_RS12360
uniprot id: A4CLW5
names: Similarity
messages: Belongs to the IMPACT family.

313596:RB2501 RS09410
gene id: 313596:RB2501_RS09410
uniprot id: A4CK44
names: Similarity
messages: Belongs to the peptidase C40 family.

313596:RB2501 RS00060
gene id: 313596:RB2501_RS00060
uniprot id: A4CG42
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell inner membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

313596:RB2501 RS13970
gene id: 313596:RB2501_RS13970
uniprot id: A4CPY7
names: Subcellular Location Annotation
messages: Membrane

313596:RB2501 RS04460
gene id: 313596:RB2501_RS04460
uniprot id: A4CIP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

313596:RB2501 RS13260
gene id: 313596:RB2501_RS13260
uniprot id: A4CNV8
names: Similarity
messages: Belongs to the proline racemase family.

313596:RB2501 RS02935
gene id: 313596:RB2501_RS02935
uniprot id: A4CHS7
names: Subcellular Location Annotation
messages: Membrane

313596:RB2501 RS14025
gene id: 313596:RB2501_RS14025
uniprot id: A4CPZ8
names: Similarity
messages: Belongs to the ParB family.

313596:RB2501 RS01210
gene id: 313596:RB2501_RS01210
uniprot id: A4CGS6
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 67 family.
messages: Homodimer.

313596:RB2501 RS12330
gene id: 313596:RB2501_RS12330
uniprot id: A4CLV9
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

313596:RB2501 RS11440
gene id: 313596:RB2501_RS11440
uniprot id: A4CLC1
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the PRA-PH family.
messages: In the N-terminal section; belongs to the PRA-CH family.

313596:RB2501 RS06525
gene id: 313596:RB2501_RS06525
uniprot id: A4CJW0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

313596:RB2501 RS00905
gene id: 313596:RB2501_RS00905
uniprot id: A4CGL3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

313596:RB2501 RS03820
gene id: 313596:RB2501_RS03820
uniprot id: A4CIB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase Slt family.
messages: Cell outer membrane
messages: Membrane

313596:RB2501 RS02205
gene id: 313596:RB2501_RS02205
uniprot id: A4CHC4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell inner membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

313596:RB2501 RS01710
gene id: 313596:RB2501_RS01710
uniprot id: A4CH24
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

313596:RB2501 RS03515
gene id: 313596:RB2501_RS03515
uniprot id: A4CI52
names: Similarity
messages: Belongs to the LacAB/RpiB family.

313596:RB2501 RS12085
gene id: 313596:RB2501_RS12085
uniprot id: A4CLQ9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

313596:RB2501 RS12335
gene id: 313596:RB2501_RS12335
uniprot id: A4CLW0
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

313596:RB2501 RS00290
gene id: 313596:RB2501_RS00290
uniprot id: A4CG89
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell inner membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: Membrane

313596:RB2501 RS03955
gene id: 313596:RB2501_RS03955
uniprot id: A4CIE1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

313596:RB2501 RS15645
gene id: 313596:RB2501_RS15645
uniprot id: A4CPU5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

313596:RB2501 RS05275
gene id: 313596:RB2501_RS05275
uniprot id: A4CJ59
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

313596:RB2501 RS14245
gene id: 313596:RB2501_RS14245
uniprot id: A4CQ44
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell inner membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

313596:RB2501 RS04005
gene id: 313596:RB2501_RS04005
uniprot id: A4CIF1
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

313596:RB2501 RS00910
gene id: 313596:RB2501_RS00910
uniprot id: A4CGL4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. tRNA (adenine-N(6)-)-methyltransferase family.
messages: Cytoplasm
messages: Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC).

313596:RB2501 RS05390
gene id: 313596:RB2501_RS05390
uniprot id: A4CJ84
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

313596:RB2501 RS06075
gene id: 313596:RB2501_RS06075
uniprot id: A4CJM1
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the peroxidase family. Peroxidase/catalase subfamily.
messages: Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.
messages: Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

313596:RB2501 RS04615
gene id: 313596:RB2501_RS04615
uniprot id: A4CIS6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

313596:RB2501 RS03560
gene id: 313596:RB2501_RS03560
uniprot id: A4CI61
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

313596:RB2501 RS07130
gene id: 313596:RB2501_RS07130
uniprot id: A4CM77
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

313596:RB2501 RS14460
gene id: 313596:RB2501_RS14460
uniprot id: A4CQ90
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

313596:RB2501 RS12610
gene id: 313596:RB2501_RS12610
uniprot id: A4CNH0
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

313596:RB2501 RS02655
gene id: 313596:RB2501_RS02655
uniprot id: A4CHL8
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

313596:RB2501 RS12520
gene id: 313596:RB2501_RS12520
uniprot id: A4CQA9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

313596:RB2501 RS09980
gene id: 313596:RB2501_RS09980
uniprot id: A4CKG2
names: Subcellular Location Annotation
messages: Membrane

313596:RB2501 RS04660
gene id: 313596:RB2501_RS04660
uniprot id: A4CIT5
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

313596:RB2501 RS02285
gene id: 313596:RB2501_RS02285
uniprot id: A4CHE1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

313596:RB2501 RS14405
gene id: 313596:RB2501_RS14405
uniprot id: A4CQ77
names: Similarity
messages: Belongs to the IPP isomerase type 1 family.

313596:RB2501 RS12810
gene id: 313596:RB2501_RS12810
uniprot id: A4CNL5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

313596:RB2501 RS02335
gene id: 313596:RB2501_RS02335
uniprot id: A4CHF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane

313596:RB2501 RS04140
gene id: 313596:RB2501_RS04140
uniprot id: A4CIH8
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

313596:RB2501 RS14635
gene id: 313596:RB2501_RS14635
uniprot id: A4CP85
names: Function
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.

313596:RB2501 RS14620
gene id: 313596:RB2501_RS14620
uniprot id: A4CP81
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

313596:RB2501 RS14645
gene id: 313596:RB2501_RS14645
uniprot id: A4CP88
names: Similarity
messages: Belongs to the UPF0246 family.

313596:RB2501 RS12260
gene id: 313596:RB2501_RS12260
uniprot id: A4CLU5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

313596:RB2501 RS10850
gene id: 313596:RB2501_RS10850
uniprot id: A4CKZ7
names: Similarity
messages: Belongs to the glycosyl hydrolase 16 family.

313596:RB2501 RS10300
gene id: 313596:RB2501_RS10300
uniprot id: A4CKM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta sliding clamp family.
messages: Cytoplasm

313596:RB2501 RS07125
gene id: 313596:RB2501_RS07125
uniprot id: A4CM76
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the adenylate cyclase family. DacA/CdaA subfamily.
messages: Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably a homodimer.

313596:RB2501 RS02240
gene id: 313596:RB2501_RS02240
uniprot id: A4CHD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

313596:RB2501 RS07865
gene id: 313596:RB2501_RS07865
uniprot id: A4CMM8
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

313596:RB2501 RS13415
gene id: 313596:RB2501_RS13415
uniprot id: A4CNZ0
names: Subcellular Location Annotation
messages: Cytoplasm

313596:RB2501 RS02765
gene id: 313596:RB2501_RS02765
uniprot id: A4CHP1
names: Subcellular Location Annotation
messages: Membrane

313596:RB2501 RS01855
gene id: 313596:RB2501_RS01855
uniprot id: A4CH53
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

313596:RB2501 RS03160
gene id: 313596:RB2501_RS03160
uniprot id: A4CHX8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

313596:RB2501 RS14475
gene id: 313596:RB2501_RS14475
uniprot id: A4CQ93
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

313596:RB2501 RS15975
gene id: 313596:RB2501_RS15975
uniprot id: A4CJW3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

313596:RB2501 RS00330
gene id: 313596:RB2501_RS00330
uniprot id: A4CG98
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueG family.
messages: Binds 2 [4Fe-4S] clusters per monomer.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

313596:RB2501 RS06375
gene id: 313596:RB2501_RS06375
uniprot id: A4CJT0
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

313596:RB2501 RS12560
gene id: 313596:RB2501_RS12560
uniprot id: A4CNG0
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

313596:RB2501 RS05250
gene id: 313596:RB2501_RS05250
uniprot id: A4CJ54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

313596:RB2501 RS07240
gene id: 313596:RB2501_RS07240
uniprot id: A4CMA0
names: Subcellular Location Annotation
messages: Membrane

313596:RB2501 RS07840
gene id: 313596:RB2501_RS07840
uniprot id: A4CMM3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

313596:RB2501 RS09030
gene id: 313596:RB2501_RS09030
uniprot id: A4CNC2
names: Similarity
messages: Belongs to the peptidase M28 family. M28B subfamily.

313596:RB2501 RS07110
gene id: 313596:RB2501_RS07110
uniprot id: A4CM73
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

313596:RB2501 RS07140
gene id: 313596:RB2501_RS07140
uniprot id: A4CM79
names: Subcellular Location Annotation
messages: Membrane

313596:RB2501 RS09070
gene id: 313596:RB2501_RS09070
uniprot id: A4CND0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

313596:RB2501 RS04515
gene id: 313596:RB2501_RS04515
uniprot id: A4CIQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm
messages: Homodimer.

313596:RB2501 RS11445
gene id: 313596:RB2501_RS11445
uniprot id: A4CLC2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

313596:RB2501 RS05080
gene id: 313596:RB2501_RS05080
uniprot id: A4CJ20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

313596:RB2501 RS10980
gene id: 313596:RB2501_RS10980
uniprot id: A4CL23
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reduced FMN (FMNH(2)).

313596:RB2501 RS05805
gene id: 313596:RB2501_RS05805
uniprot id: A4CJG9
names: Similarity
messages: Belongs to the ACC deaminase/D-cysteine desulfhydrase family.

313596:RB2501 RS02110
gene id: 313596:RB2501_RS02110
uniprot id: A4CHA5
names: Cofactor
names: Similarity
messages: Belongs to the peptidase S45 family.
messages: Binds 1 Ca(2+) ion per dimer.

313596:RB2501 RS07150
gene id: 313596:RB2501_RS07150
uniprot id: A4CM81
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

313596:RB2501 RS09885
gene id: 313596:RB2501_RS09885
uniprot id: A4CKE1
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

313596:RB2501 RS15555
gene id: 313596:RB2501_RS15555
uniprot id: A4CPS7
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

313596:RB2501 RS06175
gene id: 313596:RB2501_RS06175
uniprot id: A4CJP1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the CobB/CobQ family.
messages: Involved in acetate metabolism.
messages: The N-terminal region seems to be important for proper quaternary structure. The C-terminal region contains the substrate-binding site.

313596:RB2501 RS14605
gene id: 313596:RB2501_RS14605
uniprot id: A4CP78
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

313596:RB2501 RS07085
gene id: 313596:RB2501_RS07085
uniprot id: A4CM69
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

313596:RB2501 RS01545
gene id: 313596:RB2501_RS01545
uniprot id: A4CGZ2
names: Subcellular Location Annotation
messages: Membrane

313596:RB2501 RS10650
gene id: 313596:RB2501_RS10650
uniprot id: A4CKV7
names: Subcellular Location Annotation
messages: Membrane

313596:RB2501 RS09135
gene id: 313596:RB2501_RS09135
uniprot id: A4CNE4
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

313596:RB2501 RS09710
gene id: 313596:RB2501_RS09710
uniprot id: A4CKA4
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

313596:RB2501 RS04100
gene id: 313596:RB2501_RS04100
uniprot id: A4CIG9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

313596:RB2501 RS04555
gene id: 313596:RB2501_RS04555
uniprot id: A4CIR3
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

313596:RB2501 RS03165
gene id: 313596:RB2501_RS03165
uniprot id: A4CHX9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

313596:RB2501 RS06965
gene id: 313596:RB2501_RS06965
uniprot id: A4CM47
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

313596:RB2501 RS10195
gene id: 313596:RB2501_RS10195
uniprot id: A4CKK4
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

313596:RB2501 RS04920
gene id: 313596:RB2501_RS04920
uniprot id: A4CIY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0382 family.
messages: Membrane

313596:RB2501 RS08545
gene id: 313596:RB2501_RS08545
uniprot id: A4CN18
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

313596:RB2501 RS14090
gene id: 313596:RB2501_RS14090
uniprot id: A4CQ12
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

313596:RB2501 RS02920
gene id: 313596:RB2501_RS02920
uniprot id: A4CHS4
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.

313596:RB2501 RS10610
gene id: 313596:RB2501_RS10610
uniprot id: A4CKU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

313596:RB2501 RS01870
gene id: 313596:RB2501_RS01870
uniprot id: A4CH56
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

313596:RB2501 RS08355
gene id: 313596:RB2501_RS08355
uniprot id: A4CMX9
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

313596:RB2501 RS14780
gene id: 313596:RB2501_RS14780
uniprot id: A4CPB6
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

313596:RB2501 RS03965
gene id: 313596:RB2501_RS03965
uniprot id: A4CIE3
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

313596:RB2501 RS10765
gene id: 313596:RB2501_RS10765
uniprot id: A4CKY0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

313596:RB2501 RS06160
gene id: 313596:RB2501_RS06160
uniprot id: A4CJN8
names: Similarity
messages: Belongs to the glycosyl hydrolase 32 family.

313596:RB2501 RS04420
gene id: 313596:RB2501_RS04420
uniprot id: A4CIN6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

313596:RB2501 RS07260
gene id: 313596:RB2501_RS07260
uniprot id: A4CMA4
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

313596:RB2501 RS05045
gene id: 313596:RB2501_RS05045
uniprot id: A4CJ13
names: Similarity
messages: Belongs to the DSD1 family.

313596:RB2501 RS10090
gene id: 313596:RB2501_RS10090
uniprot id: A4CKI2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

313596:RB2501 RS04160
gene id: 313596:RB2501_RS04160
uniprot id: A4CII2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

313596:RB2501 RS04895
gene id: 313596:RB2501_RS04895
uniprot id: A4CIY3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

313596:RB2501 RS06110
gene id: 313596:RB2501_RS06110
uniprot id: A4CJM8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the arabinose isomerase family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of L-arabinose to L-ribulose.

313596:RB2501 RS06905
gene id: 313596:RB2501_RS06905
uniprot id: A4CM35
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

313596:RB2501 RS11785
gene id: 313596:RB2501_RS11785
uniprot id: A4CLJ5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

313596:RB2501 RS14735
gene id: 313596:RB2501_RS14735
uniprot id: A4CPA6
names: Similarity
messages: Belongs to the creatininase superfamily.

313596:RB2501 RS04395
gene id: 313596:RB2501_RS04395
uniprot id: A4CIN0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

313596:RB2501 RS09830
gene id: 313596:RB2501_RS09830
uniprot id: A4CKC8
names: Subcellular Location Annotation
messages: Membrane

313596:RB2501 RS15015
gene id: 313596:RB2501_RS15015
uniprot id: A4CPG3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NqrA family.
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

313596:RB2501 RS01580
gene id: 313596:RB2501_RS01580
uniprot id: A4CGZ8
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

313596:RB2501 RS07985
gene id: 313596:RB2501_RS07985
uniprot id: A4CMQ3
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

313596:RB2501 RS09180
gene id: 313596:RB2501_RS09180
uniprot id: A4CJZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

313596:RB2501 RS01845
gene id: 313596:RB2501_RS01845
uniprot id: A4CH51
names: Similarity
messages: Belongs to the histone deacetylase family.

313596:RB2501 RS12320
gene id: 313596:RB2501_RS12320
uniprot id: A4CLV7
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

313596:RB2501 RS07235
gene id: 313596:RB2501_RS07235
uniprot id: A4CM99
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

313596:RB2501 RS07580
gene id: 313596:RB2501_RS07580
uniprot id: A4CMG8
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

313596:RB2501 RS05955
gene id: 313596:RB2501_RS05955
uniprot id: A4CJJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

313596:RB2501 RS03045
gene id: 313596:RB2501_RS03045
uniprot id: A4CHV3
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

313596:RB2501 RS13990
gene id: 313596:RB2501_RS13990
uniprot id: A4CPZ1
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

313596:RB2501 RS09085
gene id: 313596:RB2501_RS09085
uniprot id: A4CND3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

313596:RB2501 RS12005
gene id: 313596:RB2501_RS12005
uniprot id: A4CLP3
names: Similarity
messages: Belongs to the CvfB family.

313596:RB2501 RS01425
gene id: 313596:RB2501_RS01425
uniprot id: A4CGW7
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

313596:RB2501 RS14280
gene id: 313596:RB2501_RS14280
uniprot id: A4CQ51
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

313596:RB2501 RS12305
gene id: 313596:RB2501_RS12305
uniprot id: A4CLV4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

313596:RB2501 RS09610
gene id: 313596:RB2501_RS09610
uniprot id: A4CK84
names: Similarity
messages: Belongs to the glycosyl hydrolase 130 family.

313596:RB2501 RS14040
gene id: 313596:RB2501_RS14040
uniprot id: A4CQ01
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

313596:RB2501 RS00525
gene id: 313596:RB2501_RS00525
uniprot id: A4CGD7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

313596:RB2501 RS07025
gene id: 313596:RB2501_RS07025
uniprot id: A4CM58
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

313596:RB2501 RS11835
gene id: 313596:RB2501_RS11835
uniprot id: A4CLK6
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

313596:RB2501 RS12555
gene id: 313596:RB2501_RS12555
uniprot id: A4CNF9
names: Subcellular Location Annotation
messages: Membrane

313596:RB2501 RS03025
gene id: 313596:RB2501_RS03025
uniprot id: A4CHU7
names: Similarity
messages: Belongs to the peptidase C56 family.

313596:RB2501 RS00315
gene id: 313596:RB2501_RS00315
uniprot id: A4CG94
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

313596:RB2501 RS03330
gene id: 313596:RB2501_RS03330
uniprot id: A4CI13
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.
messages: Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

313596:RB2501 RS10055
gene id: 313596:RB2501_RS10055
uniprot id: A4CKH5
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

313596:RB2501 RS00770
gene id: 313596:RB2501_RS00770
uniprot id: A4CGI5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

313596:RB2501 RS04455
gene id: 313596:RB2501_RS04455
uniprot id: A4CIP3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

313596:RB2501 RS14255
gene id: 313596:RB2501_RS14255
uniprot id: A4CQ46
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

313596:RB2501 RS03020
gene id: 313596:RB2501_RS03020
uniprot id: A4CHU5
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

313596:RB2501 RS02545
gene id: 313596:RB2501_RS02545
uniprot id: A4CHJ6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HemJ family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Catalyzes the oxidation of protoporphyrinogen IX to protoporphyrin IX.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

313596:RB2501 RS05635
gene id: 313596:RB2501_RS05635
uniprot id: A4CJD3
names: Subcellular Location Annotation
messages: Membrane

313596:RB2501 RS00350
gene id: 313596:RB2501_RS00350
uniprot id: A4CGA2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

313596:RB2501 RS15235
gene id: 313596:RB2501_RS15235
uniprot id: A4CPL0
names: Subcellular Location Annotation
messages: Membrane

313596:RB2501 RS13270
gene id: 313596:RB2501_RS13270
uniprot id: A4CNW0
names: Similarity
messages: Belongs to the DapA family.

313596:RB2501 RS14000
gene id: 313596:RB2501_RS14000
uniprot id: A4CPZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uridine kinase family.
messages: Cytoplasm

313596:RB2501 RS02310
gene id: 313596:RB2501_RS02310
uniprot id: A4CHE6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

313596:RB2501 RS03145
gene id: 313596:RB2501_RS03145
uniprot id: A4CHX5
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

313596:RB2501 RS04560
gene id: 313596:RB2501_RS04560
uniprot id: A4CIR4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

313596:RB2501 RS15600
gene id: 313596:RB2501_RS15600
uniprot id: A4CPT6
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

313596:RB2501 RS06605
gene id: 313596:RB2501_RS06605
uniprot id: A4CJX8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

313596:RB2501 RS14860
gene id: 313596:RB2501_RS14860
uniprot id: A4CPD2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

313596:RB2501 RS06420
gene id: 313596:RB2501_RS06420
uniprot id: A4CJT9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

313596:RB2501 RS15350
gene id: 313596:RB2501_RS15350
uniprot id: A4CPN6
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

313596:RB2501 RS05010
gene id: 313596:RB2501_RS05010
uniprot id: A4CJ06
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.
messages: In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: In the N-terminal section; belongs to the MIP18 family.

313596:RB2501 RS12280
gene id: 313596:RB2501_RS12280
uniprot id: A4CLU9
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

313596:RB2501 RS07685
gene id: 313596:RB2501_RS07685
uniprot id: A4CMJ0
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

313596:RB2501 RS14250
gene id: 313596:RB2501_RS14250
uniprot id: A4CQ45
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

313596:RB2501 RS14470
gene id: 313596:RB2501_RS14470
uniprot id: A4CQ92
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

313596:RB2501 RS10175
gene id: 313596:RB2501_RS10175
uniprot id: A4CKK0
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Homotetramer.

313596:RB2501 RS02640
gene id: 313596:RB2501_RS02640
uniprot id: A4CHL5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

313596:RB2501 RS01945
gene id: 313596:RB2501_RS01945
uniprot id: A4CH72
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

313596:RB2501 RS10770
gene id: 313596:RB2501_RS10770
uniprot id: A4CKY1
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

313596:RB2501 RS09725
gene id: 313596:RB2501_RS09725
uniprot id: A4CKA7
names: Similarity
messages: Belongs to the PAPS reductase family. CysD subfamily.

313596:RB2501 RS14300
gene id: 313596:RB2501_RS14300
uniprot id: A4CQ55
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

313596:RB2501 RS12565
gene id: 313596:RB2501_RS12565
uniprot id: A4CNG1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

313596:RB2501 RS15270
gene id: 313596:RB2501_RS15270
uniprot id: A4CPL7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

313596:RB2501 RS08080
gene id: 313596:RB2501_RS08080
uniprot id: A4CMS2
names: Similarity
messages: Belongs to the aldose epimerase family.

313596:RB2501 RS00555
gene id: 313596:RB2501_RS00555
uniprot id: A4CGE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

313596:RB2501 RS14535
gene id: 313596:RB2501_RS14535
uniprot id: A4CQA0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

313596:RB2501 RS12240
gene id: 313596:RB2501_RS12240
uniprot id: A4CLU1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

313596:RB2501 RS02485
gene id: 313596:RB2501_RS02485
uniprot id: A4CHI4
names: Similarity
messages: Belongs to the peptidase S41A family.

313596:RB2501 RS11375
gene id: 313596:RB2501_RS11375
uniprot id: A4CLA8
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

313596:RB2501 RS03265
gene id: 313596:RB2501_RS03265
uniprot id: A4CI00
names: Similarity
messages: Belongs to the GARS family.

313596:RB2501 RS01010
gene id: 313596:RB2501_RS01010
uniprot id: A4CGN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

313596:RB2501 RS08930
gene id: 313596:RB2501_RS08930
uniprot id: A4CNA1
names: Similarity
messages: Belongs to the BshC family.

313596:RB2501 RS05455
gene id: 313596:RB2501_RS05455
uniprot id: A4CJ97
names: Function
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

313596:RB2501 RS00050
gene id: 313596:RB2501_RS00050
uniprot id: A4CG40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Membrane

313596:RB2501 RS06450
gene id: 313596:RB2501_RS06450
uniprot id: A4CJU5
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

313596:RB2501 RS10170
gene id: 313596:RB2501_RS10170
uniprot id: A4CKJ9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

313596:RB2501 RS14585
gene id: 313596:RB2501_RS14585
uniprot id: A4CP74
names: Similarity
messages: Belongs to the nitroreductase family.

313596:RB2501 RS10540
gene id: 313596:RB2501_RS10540
uniprot id: A4CKT1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

313596:RB2501 RS11470
gene id: 313596:RB2501_RS11470
uniprot id: A4CLC7
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

313596:RB2501 RS00320
gene id: 313596:RB2501_RS00320
uniprot id: A4CG95
names: Similarity
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the malic enzymes family.

313596:RB2501 RS14155
gene id: 313596:RB2501_RS14155
uniprot id: A4CQ26
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

313596:RB2501 RS14810
gene id: 313596:RB2501_RS14810
uniprot id: A4CPC2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

313596:RB2501 RS07585
gene id: 313596:RB2501_RS07585
uniprot id: A4CMG9
names: Similarity
messages: Belongs to the OMP decarboxylase family. Type 2 subfamily.

313596:RB2501 RS15410
gene id: 313596:RB2501_RS15410
uniprot id: A4CPP8
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

313596:RB2501 RS00140
gene id: 313596:RB2501_RS00140
uniprot id: A4CG56
names: Similarity
messages: Belongs to the fabD family.

313596:RB2501 RS07875
gene id: 313596:RB2501_RS07875
uniprot id: A4CMN0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

313596:RB2501 RS06540
gene id: 313596:RB2501_RS06540
uniprot id: A4CJW4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

313596:RB2501 RS03960
gene id: 313596:RB2501_RS03960
uniprot id: A4CIE2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

313596:RB2501 RS11260
gene id: 313596:RB2501_RS11260
uniprot id: A4CL82
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

313596:RB2501 RS02290
gene id: 313596:RB2501_RS02290
uniprot id: A4CHE2
names: Subcellular Location Annotation
messages: Membrane

313596:RB2501 RS11395
gene id: 313596:RB2501_RS11395
uniprot id: A4CLB2
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

313596:RB2501 RS07315
gene id: 313596:RB2501_RS07315
uniprot id: A4CMB5
names: Subcellular Location Annotation
messages: Cytoplasm

313596:RB2501 RS03170
gene id: 313596:RB2501_RS03170
uniprot id: A4CHY0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase delta chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

313596:RB2501 RS06545
gene id: 313596:RB2501_RS06545
uniprot id: A4CJW5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

313596:RB2501 RS03395
gene id: 313596:RB2501_RS03395
uniprot id: A4CI28
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

313596:RB2501 RS12400
gene id: 313596:RB2501_RS12400
uniprot id: A4CLX3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

313596:RB2501 RS13360
gene id: 313596:RB2501_RS13360
uniprot id: A4CNX9
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

313596:RB2501 RS12290
gene id: 313596:RB2501_RS12290
uniprot id: A4CLV1
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

313596:RB2501 RS00085
gene id: 313596:RB2501_RS00085
uniprot id: A4CG47
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaved by autocatalysis into a large and a small subunit.
messages: This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide.

313596:RB2501 RS06295
gene id: 313596:RB2501_RS06295
uniprot id: A4CJR4
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

313596:RB2501 RS04135
gene id: 313596:RB2501_RS04135
uniprot id: A4CIH7
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

313596:RB2501 RS14285
gene id: 313596:RB2501_RS14285
uniprot id: A4CQ52
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

313596:RB2501 RS05830
gene id: 313596:RB2501_RS05830
uniprot id: A4CJH5
names: Subcellular Location Annotation
messages: Membrane

313596:RB2501 RS08385
gene id: 313596:RB2501_RS08385
uniprot id: A4CMY5
names: Similarity
messages: Belongs to the thioredoxin family.

313596:RB2501 RS02225
gene id: 313596:RB2501_RS02225
uniprot id: A4CHC9
names: Similarity
messages: Belongs to the DinB family.

313596:RB2501 RS05505
gene id: 313596:RB2501_RS05505
uniprot id: A4CJA7
names: Similarity
messages: Belongs to the MreC family.

313596:RB2501 RS04315
gene id: 313596:RB2501_RS04315
uniprot id: A4CIL4
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

313596:RB2501 RS06460
gene id: 313596:RB2501_RS06460
uniprot id: A4CJU7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

313596:RB2501 RS06120
gene id: 313596:RB2501_RS06120
uniprot id: A4CJN0
names: Similarity
messages: Belongs to the ribulokinase family.

313596:RB2501 RS04855
gene id: 313596:RB2501_RS04855
uniprot id: A4CIX4
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

313596:RB2501 RS09400
gene id: 313596:RB2501_RS09400
uniprot id: A4CK42
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

313596:RB2501 RS12780
gene id: 313596:RB2501_RS12780
uniprot id: A4CNK9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL31 family.

313596:RB2501 RS07995
gene id: 313596:RB2501_RS07995
uniprot id: A4CMQ5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

313596:RB2501 RS11790
gene id: 313596:RB2501_RS11790
uniprot id: A4CLJ7
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

313596:RB2501 RS13245
gene id: 313596:RB2501_RS13245
uniprot id: A4CNV5
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

313596:RB2501 RS09640
gene id: 313596:RB2501_RS09640
uniprot id: A4CK90
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

313596:RB2501 RS07885
gene id: 313596:RB2501_RS07885
uniprot id: A4CMN2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

313596:RB2501 RS07705
gene id: 313596:RB2501_RS07705
uniprot id: A4CMJ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

313596:RB2501 RS07490
gene id: 313596:RB2501_RS07490
uniprot id: A4CMF0
names: Subcellular Location Annotation
messages: Membrane

313596:RB2501 RS03335
gene id: 313596:RB2501_RS03335
uniprot id: A4CI14
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

313596:RB2501 RS02645
gene id: 313596:RB2501_RS02645
uniprot id: A4CHL6
names: Subcellular Location Annotation
messages: Membrane

313596:RB2501 RS01940
gene id: 313596:RB2501_RS01940
uniprot id: A4CH71
names: Similarity
messages: Belongs to the deoxyhypusine synthase family.

313596:RB2501 RS03600
gene id: 313596:RB2501_RS03600
uniprot id: A4CI69
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell inner membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

313596:RB2501 RS07905
gene id: 313596:RB2501_RS07905
uniprot id: A4CMN7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

313596:RB2501 RS14765
gene id: 313596:RB2501_RS14765
uniprot id: A4CPB3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

313596:RB2501 RS14815
gene id: 313596:RB2501_RS14815
uniprot id: A4CPC3
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

313596:RB2501 RS03150
gene id: 313596:RB2501_RS03150
uniprot id: A4CHX6
names: Subcellular Location Annotation
messages: Membrane

313596:RB2501 RS12115
gene id: 313596:RB2501_RS12115
uniprot id: A4CLR5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

313596:RB2501 RS00605
gene id: 313596:RB2501_RS00605
uniprot id: A4CGF2
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

313596:RB2501 RS00500
gene id: 313596:RB2501_RS00500
uniprot id: A4CGD2
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

313596:RB2501 RS12425
gene id: 313596:RB2501_RS12425
uniprot id: A4CLX8
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

313596:RB2501 RS12205
gene id: 313596:RB2501_RS12205
uniprot id: A4CLT3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
messages: Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.
messages: Cytoplasm

313596:RB2501 RS06490
gene id: 313596:RB2501_RS06490
uniprot id: A4CJV3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

313596:RB2501 RS08825
gene id: 313596:RB2501_RS08825
uniprot id: A4CN79
names: Subcellular Location Annotation
messages: Membrane

313596:RB2501 RS00875
gene id: 313596:RB2501_RS00875
uniprot id: A4CGK7
names: Similarity
messages: Belongs to the Gfo/Idh/MocA family. Glycosyl hydrolase 109 subfamily.

313596:RB2501 RS00220
gene id: 313596:RB2501_RS00220
uniprot id: A4CG74
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

313596:RB2501 RS15280
gene id: 313596:RB2501_RS15280
uniprot id: A4CPM0
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

313596:RB2501 RS02560
gene id: 313596:RB2501_RS02560
uniprot id: A4CHJ9
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

313596:RB2501 RS12750
gene id: 313596:RB2501_RS12750
uniprot id: A4CNK2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase D family. Cardiolipin synthase subfamily.
messages: Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
messages: Cell inner membrane
messages: Membrane

313596:RB2501 RS13215
gene id: 313596:RB2501_RS13215
uniprot id: A4CNU9
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

313596:RB2501 RS01765
gene id: 313596:RB2501_RS01765
uniprot id: A4CH35
names: Similarity
messages: Belongs to the aspartokinase family.

313596:RB2501 RS00535
gene id: 313596:RB2501_RS00535
uniprot id: A4CGD9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

313596:RB2501 RS12685
gene id: 313596:RB2501_RS12685
uniprot id: A4CNI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

313596:RB2501 RS04145
gene id: 313596:RB2501_RS04145
uniprot id: A4CIH9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

313596:RB2501 RS07665
gene id: 313596:RB2501_RS07665
uniprot id: A4CMI6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell inner membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

313596:RB2501 RS15055
gene id: 313596:RB2501_RS15055
uniprot id: A4CPH3
names: Subcellular Location Annotation
messages: Membrane

313596:RB2501 RS15385
gene id: 313596:RB2501_RS15385
uniprot id: A4CPP3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

313596:RB2501 RS08315
gene id: 313596:RB2501_RS08315
uniprot id: A4CMX2
names: Subcellular Location Annotation
messages: Mitochondrion

313596:RB2501 RS14480
gene id: 313596:RB2501_RS14480
uniprot id: A4CQ94
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

313596:RB2501 RS02410
gene id: 313596:RB2501_RS02410
uniprot id: A4CHG7
names: Similarity
messages: Belongs to the DinB family.

313596:RB2501 RS15470
gene id: 313596:RB2501_RS15470
uniprot id: A4CPR0
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the ferredoxin--NADP reductase type 2 family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

313596:RB2501 RS00440
gene id: 313596:RB2501_RS00440
uniprot id: A4CGC1
names: Subcellular Location Annotation
messages: Membrane

313596:RB2501 RS00520
gene id: 313596:RB2501_RS00520
uniprot id: A4CGD6
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

313596:RB2501 RS07220
gene id: 313596:RB2501_RS07220
uniprot id: A4CM96
names: Similarity
messages: Belongs to the AHA1 family.

313596:RB2501 RS04290
gene id: 313596:RB2501_RS04290
uniprot id: A4CIK9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 3-HAO family.
messages: Binds 2 Fe(2+) ions per subunit.
messages: Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.

313596:RB2501 RS04925
gene id: 313596:RB2501_RS04925
uniprot id: A4CIY9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Cytoplasm
messages: Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

313596:RB2501 RS11860
gene id: 313596:RB2501_RS11860
uniprot id: A4CLL1
names: Similarity
messages: Belongs to the threonine aldolase family.

313596:RB2501 RS12130
gene id: 313596:RB2501_RS12130
uniprot id: A4CLR8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

313596:RB2501 RS00800
gene id: 313596:RB2501_RS00800
uniprot id: A4CGJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAL/histidase family.
messages: Cytoplasm

313596:RB2501 RS11315
gene id: 313596:RB2501_RS11315
uniprot id: A4CL94
names: Caution
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
messages: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

313596:RB2501 RS03275
gene id: 313596:RB2501_RS03275
uniprot id: A4CI02
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

313596:RB2501 RS03390
gene id: 313596:RB2501_RS03390
uniprot id: A4CI27
names: Similarity
messages: Belongs to the transglycosylase Slt family.

313596:RB2501 RS07540
gene id: 313596:RB2501_RS07540
uniprot id: A4CMG0
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

313596:RB2501 RS03435
gene id: 313596:RB2501_RS03435
uniprot id: A4CI36
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

313596:RB2501 RS12530
gene id: 313596:RB2501_RS12530
uniprot id: A4CNF4
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

313596:RB2501 RS03180
gene id: 313596:RB2501_RS03180
uniprot id: A4CHY2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase C chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

313596:RB2501 RS07340
gene id: 313596:RB2501_RS07340
uniprot id: A4CMC0
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

313596:RB2501 RS04890
gene id: 313596:RB2501_RS04890
uniprot id: A4CIY1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Required for cell division and gliding motility.

313596:RB2501 RS00250
gene id: 313596:RB2501_RS00250
uniprot id: A4CG80
names: Subcellular Location Annotation
messages: Membrane

313596:RB2501 RS00820
gene id: 313596:RB2501_RS00820
uniprot id: A4CGJ5
names: Similarity
messages: Belongs to the homogentisate dioxygenase family.

313596:RB2501 RS10645
gene id: 313596:RB2501_RS10645
uniprot id: A4CKV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Membrane

313596:RB2501 RS07065
gene id: 313596:RB2501_RS07065
uniprot id: A4CM65
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

313596:RB2501 RS02730
gene id: 313596:RB2501_RS02730
uniprot id: A4CHN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

313596:RB2501 RS07520
gene id: 313596:RB2501_RS07520
uniprot id: A4CMF5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

313596:RB2501 RS15290
gene id: 313596:RB2501_RS15290
uniprot id: A4CPM2
names: Similarity
messages: Belongs to the pirin family.

313596:RB2501 RS12540
gene id: 313596:RB2501_RS12540
uniprot id: A4CNF6
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

313596:RB2501 RS14790
gene id: 313596:RB2501_RS14790
uniprot id: A4CPB8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

313596:RB2501 RS00280
gene id: 313596:RB2501_RS00280
uniprot id: A4CG87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Membrane

313596:RB2501 RS15345
gene id: 313596:RB2501_RS15345
uniprot id: A4CPN4
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

313596:RB2501 RS04000
gene id: 313596:RB2501_RS04000
uniprot id: A4CIF0
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

313596:RB2501 RS09145
gene id: 313596:RB2501_RS09145
uniprot id: A4CNE6
names: Subcellular Location Annotation
messages: Membrane

313596:RB2501 RS10700
gene id: 313596:RB2501_RS10700
uniprot id: A4CKW7
names: Cofactor
names: Similarity
messages: Belongs to the peptidase S45 family.
messages: Binds 1 Ca(2+) ion per dimer.

313596:RB2501 RS14530
gene id: 313596:RB2501_RS14530
uniprot id: A4CQ99
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

313596:RB2501 RS07215
gene id: 313596:RB2501_RS07215
uniprot id: A4CM95
names: Similarity
messages: Belongs to the peptidase S15 family.

313596:RB2501 RS04015
gene id: 313596:RB2501_RS04015
uniprot id: A4CIF3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

313596:RB2501 RS05480
gene id: 313596:RB2501_RS05480
uniprot id: A4CJA2
names: Cofactor
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Binds 1 zinc ion per subunit. The zinc ion is important for the structural integrity of the protein.

313596:RB2501 RS12630
gene id: 313596:RB2501_RS12630
uniprot id: A4CNH4
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 2 residues (Tyr-53 and Arg-56) present in a large hydrophobic pocket are probably involved in substrate specificity. They are important for desuccinylation activity, but dispensable for deacetylation activity.
messages: Belongs to the sirtuin family. Class III subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form.

313596:RB2501 RS07795
gene id: 313596:RB2501_RS07795
uniprot id: A4CML4
names: Subcellular Location Annotation
messages: Nucleus

313596:RB2501 RS02300
gene id: 313596:RB2501_RS02300
uniprot id: A4CHE4
names: Subcellular Location Annotation
messages: Cytoplasm

313596:RB2501 RS13435
gene id: 313596:RB2501_RS13435
uniprot id: A4CNZ4
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

313596:RB2501 RS02190
gene id: 313596:RB2501_RS02190
uniprot id: A4CHC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

313596:RB2501 RS08955
gene id: 313596:RB2501_RS08955
uniprot id: A4CNA7
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

313596:RB2501 RS14175
gene id: 313596:RB2501_RS14175
uniprot id: A4CQ30
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

313596:RB2501 RS12975
gene id: 313596:RB2501_RS12975
uniprot id: A4CNP9
names: Subcellular Location Annotation
messages: Membrane

313596:RB2501 RS03110
gene id: 313596:RB2501_RS03110
uniprot id: A4CHW7
names: Similarity
messages: Belongs to the DprA/Smf family.

313596:RB2501 RS14150
gene id: 313596:RB2501_RS14150
uniprot id: A4CQ25
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

313596:RB2501 RS14060
gene id: 313596:RB2501_RS14060
uniprot id: A4CQ05
names: Subcellular Location Annotation
messages: Membrane

313596:RB2501 RS01370
gene id: 313596:RB2501_RS01370
uniprot id: A4CGV6
names: Similarity
messages: Belongs to the glutamate synthase family.

313596:RB2501 RS01325
gene id: 313596:RB2501_RS01325
uniprot id: A4CGU8
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

313596:RB2501 RS05215
gene id: 313596:RB2501_RS05215
uniprot id: A4CJ47
names: Activity Regulation
names: Caution
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

313596:RB2501 RS10805
gene id: 313596:RB2501_RS10805
uniprot id: A4CKY8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

313596:RB2501 RS14225
gene id: 313596:RB2501_RS14225
uniprot id: A4CQ40
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
messages: Cytoplasm

313596:RB2501 RS15250
gene id: 313596:RB2501_RS15250
uniprot id: A4CPL3
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

313596:RB2501 RS04125
gene id: 313596:RB2501_RS04125
uniprot id: A4CIH5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase H family.
messages: Binds 2 metal ions per subunit. Manganese or magnesium.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.

313596:RB2501 RS10125
gene id: 313596:RB2501_RS10125
uniprot id: A4CKI9
names: Similarity
messages: Belongs to the DNA photolyase family.

313596:RB2501 RS09120
gene id: 313596:RB2501_RS09120
uniprot id: A4CNE1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgE subfamily.
messages: Homodimer.
messages: Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1->4)-glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB.

313596:RB2501 RS04590
gene id: 313596:RB2501_RS04590
uniprot id: A4CIS1
names: Similarity
messages: Belongs to the ATPase epsilon chain family.

313596:RB2501 RS14185
gene id: 313596:RB2501_RS14185
uniprot id: A4CQ32
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

313596:RB2501 RS09250
gene id: 313596:RB2501_RS09250
uniprot id: A4CK11
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily.

313596:RB2501 RS08880
gene id: 313596:RB2501_RS08880
uniprot id: A4CN91
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

313596:RB2501 RS08375
gene id: 313596:RB2501_RS08375
uniprot id: A4CMY3
names: Subcellular Location Annotation
messages: Membrane

313596:RB2501 RS04705
gene id: 313596:RB2501_RS04705
uniprot id: A4CIU4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

313596:RB2501 RS09035
gene id: 313596:RB2501_RS09035
uniprot id: A4CNC3
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20 family.
messages: Binds 2 Zn(2+) ions per subunit.

313596:RB2501 RS14500
gene id: 313596:RB2501_RS14500
uniprot id: A4CQ97
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

313596:RB2501 RS00725
gene id: 313596:RB2501_RS00725
uniprot id: A4CGH6
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

313596:RB2501 RS05280
gene id: 313596:RB2501_RS05280
uniprot id: A4CJ60
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

313596:RB2501 RS06005
gene id: 313596:RB2501_RS06005
uniprot id: A4CJK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

313596:RB2501 RS14705
gene id: 313596:RB2501_RS14705
uniprot id: A4CPA0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein L14 (rplN).

313596:RB2501 RS05815
gene id: 313596:RB2501_RS05815
uniprot id: A4CJH1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

313596:RB2501 RS00325
gene id: 313596:RB2501_RS00325
uniprot id: A4CG97
names: Subcellular Location Annotation
messages: Membrane

313596:RB2501 RS05845
gene id: 313596:RB2501_RS05845
uniprot id: A4CJH8
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

313596:RB2501 RS03700
gene id: 313596:RB2501_RS03700
uniprot id: A4CI89
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

313596:RB2501 RS09955
gene id: 313596:RB2501_RS09955
uniprot id: A4CKF7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

313596:RB2501 RS05555
gene id: 313596:RB2501_RS05555
uniprot id: A4CJB7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

313596:RB2501 RS08780
gene id: 313596:RB2501_RS08780
uniprot id: A4CN70
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

313596:RB2501 RS14650
gene id: 313596:RB2501_RS14650
uniprot id: A4CP89
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

313596:RB2501 RS10000
gene id: 313596:RB2501_RS10000
uniprot id: A4CKG6
names: Similarity
messages: Belongs to the SAICAR synthetase family.

313596:RB2501 RS15315
gene id: 313596:RB2501_RS15315
uniprot id: A4CPM7
names: Similarity
messages: Belongs to the NAD synthetase family.

313596:RB2501 RS15060
gene id: 313596:RB2501_RS15060
uniprot id: A4CPH4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

313596:RB2501 RS10950
gene id: 313596:RB2501_RS10950
uniprot id: A4CL17
names: Subcellular Location Annotation
messages: Membrane

313596:RB2501 RS05210
gene id: 313596:RB2501_RS05210
uniprot id: A4CJ46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

313596:RB2501 RS12710
gene id: 313596:RB2501_RS12710
uniprot id: A4CNJ1
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

313596:RB2501 RS00610
gene id: 313596:RB2501_RS00610
uniprot id: A4CGF3
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

313596:RB2501 RS04190
gene id: 313596:RB2501_RS04190
uniprot id: A4CII8
names: Subcellular Location Annotation
messages: Membrane

313596:RB2501 RS05265
gene id: 313596:RB2501_RS05265
uniprot id: A4CJ57
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. SOTCase family.
messages: Catalyzes the transfer of the carbamoyl group from carbamoyl phosphate to the delta-amino group of N(2)-succinyl-L-ornithine to produce N(2)-succinyl-L-citrulline. Is essential for arginine biosynthesis.
messages: Homotrimer.

313596:RB2501 RS00420
gene id: 313596:RB2501_RS00420
uniprot id: A4CGB7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

313596:RB2501 RS11560
gene id: 313596:RB2501_RS11560
uniprot id: A4CLE7
names: Similarity
messages: Belongs to the AlaDH/PNT family.

313596:RB2501 RS08795
gene id: 313596:RB2501_RS08795
uniprot id: A4CN73
names: Similarity
messages: Belongs to the HSP15 family.

313596:RB2501 RS04540
gene id: 313596:RB2501_RS04540
uniprot id: A4CIR0
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

313596:RB2501 RS05790
gene id: 313596:RB2501_RS05790
uniprot id: A4CJG5
names: Similarity
messages: Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.

313596:RB2501 RS02355
gene id: 313596:RB2501_RS02355
uniprot id: A4CHF5
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

313596:RB2501 RS15800
gene id: 313596:RB2501_RS15800
uniprot id: A4CMW6
names: Similarity
messages: Belongs to the AHA1 family.

313596:RB2501 RS05355
gene id: 313596:RB2501_RS05355
uniprot id: A4CJ77
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

313596:RB2501 RS15525
gene id: 313596:RB2501_RS15525
uniprot id: A4CPS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Membrane

313596:RB2501 RS06515
gene id: 313596:RB2501_RS06515
uniprot id: A4CJV8
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

313596:RB2501 RS13375
gene id: 313596:RB2501_RS13375
uniprot id: A4CNY2
names: PTM
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

313596:RB2501 RS10905
gene id: 313596:RB2501_RS10905
uniprot id: A4CL08
names: Similarity
messages: Belongs to the LOG family.

313596:RB2501 RS01735
gene id: 313596:RB2501_RS01735
uniprot id: A4CH29
names: Subcellular Location Annotation
messages: Membrane

313596:RB2501 RS07620
gene id: 313596:RB2501_RS07620
uniprot id: A4CMH6
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

313596:RB2501 RS01000
gene id: 313596:RB2501_RS01000
uniprot id: A4CGN2
names: Similarity
messages: Belongs to the HypD family.

313596:RB2501 RS09415
gene id: 313596:RB2501_RS09415
uniprot id: A4CK45
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

313596:RB2501 RS11615
gene id: 313596:RB2501_RS11615
uniprot id: A4CLF8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell inner membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

313596:RB2501 RS00530
gene id: 313596:RB2501_RS00530
uniprot id: A4CGD8
names: Subcellular Location Annotation
messages: Membrane

313596:RB2501 RS09655
gene id: 313596:RB2501_RS09655
uniprot id: A4CK93
names: Subcellular Location Annotation
messages: Membrane

313596:RB2501 RS01525
gene id: 313596:RB2501_RS01525
uniprot id: A4CGY8
names: Similarity
messages: Belongs to the ribose-phosphate pyrophosphokinase family.

313596:RB2501 RS04380
gene id: 313596:RB2501_RS04380
uniprot id: A4CIM7
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

313596:RB2501 RS03345
gene id: 313596:RB2501_RS03345
uniprot id: A4CI16
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

313596:RB2501 RS02535
gene id: 313596:RB2501_RS02535
uniprot id: A4CHJ4
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

313596:RB2501 RS07180
gene id: 313596:RB2501_RS07180
uniprot id: A4CM87
names: Subcellular Location Annotation
messages: Membrane

313596:RB2501 RS05945
gene id: 313596:RB2501_RS05945
uniprot id: A4CJJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaD Na(+)/H(+) (TC 2.A.62) antiporter family.
messages: Membrane

313596:RB2501 RS08860
gene id: 313596:RB2501_RS08860
uniprot id: A4CN86
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

313596:RB2501 RS04085
gene id: 313596:RB2501_RS04085
uniprot id: A4CIG6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

313596:RB2501 RS07270
gene id: 313596:RB2501_RS07270
uniprot id: A4CMA6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

313596:RB2501 RS10620
gene id: 313596:RB2501_RS10620
uniprot id: A4CKV1
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

313596:RB2501 RS06410
gene id: 313596:RB2501_RS06410
uniprot id: A4CJT7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

313596:RB2501 RS08070
gene id: 313596:RB2501_RS08070
uniprot id: A4CMS0
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

313596:RB2501 RS03875
gene id: 313596:RB2501_RS03875
uniprot id: A4CIC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0394 family.
messages: Membrane

313596:RB2501 RS04995
gene id: 313596:RB2501_RS04995
uniprot id: A4CJ03
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

313596:RB2501 RS08835
gene id: 313596:RB2501_RS08835
uniprot id: A4CN81
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

313596:RB2501 RS03105
gene id: 313596:RB2501_RS03105
uniprot id: A4CHW6
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

313596:RB2501 RS10815
gene id: 313596:RB2501_RS10815
uniprot id: A4CKZ0
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

313596:RB2501 RS06570
gene id: 313596:RB2501_RS06570
uniprot id: A4CJX1
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

313596:RB2501 RS11410
gene id: 313596:RB2501_RS11410
uniprot id: A4CLB5
names: Similarity
messages: Belongs to the Dps family.

313596:RB2501 RS07285
gene id: 313596:RB2501_RS07285
uniprot id: A4CMA9
names: Similarity
messages: Belongs to the SusD family.

313596:RB2501 RS10435
gene id: 313596:RB2501_RS10435
uniprot id: A4CKQ8
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

313596:RB2501 RS14115
gene id: 313596:RB2501_RS14115
uniprot id: A4CQ18
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

313596:RB2501 RS11185
gene id: 313596:RB2501_RS11185
uniprot id: A4CL64
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
messages: Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.
messages: Cytoplasm

313596:RB2501 RS02670
gene id: 313596:RB2501_RS02670
uniprot id: A4CHM1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.

313596:RB2501 RS12970
gene id: 313596:RB2501_RS12970
uniprot id: A4CNP8
names: Subcellular Location Annotation
messages: Membrane

313596:RB2501 RS06580
gene id: 313596:RB2501_RS06580
uniprot id: A4CJX3
names: Similarity
messages: Belongs to the citrate synthase family.

313596:RB2501 RS02580
gene id: 313596:RB2501_RS02580
uniprot id: A4CHK3
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

313596:RB2501 RS06985
gene id: 313596:RB2501_RS06985
uniprot id: A4CM50
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 3 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

313596:RB2501 RS01840
gene id: 313596:RB2501_RS01840
uniprot id: A4CH50
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.

313596:RB2501 RS09900
gene id: 313596:RB2501_RS09900
uniprot id: A4CKE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the etk/wzc family.
messages: Cell inner membrane
messages: Membrane

313596:RB2501 RS12960
gene id: 313596:RB2501_RS12960
uniprot id: A4CNP6
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

313596:RB2501 RS05710
gene id: 313596:RB2501_RS05710
uniprot id: A4CJF0
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.

313596:RB2501 RS03520
gene id: 313596:RB2501_RS03520
uniprot id: A4CI53
names: Subcellular Location Annotation
messages: Membrane

313596:RB2501 RS01810
gene id: 313596:RB2501_RS01810
uniprot id: A4CH44
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

313596:RB2501 RS05465
gene id: 313596:RB2501_RS05465
uniprot id: A4CJ99
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

313596:RB2501 RS01035
gene id: 313596:RB2501_RS01035
uniprot id: A4CGN9
names: Similarity
messages: Belongs to the peptidase A31 family.

313596:RB2501 RS12535
gene id: 313596:RB2501_RS12535
uniprot id: A4CNF5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

313596:RB2501 RS12590
gene id: 313596:RB2501_RS12590
uniprot id: A4CNG6
names: Subcellular Location Annotation
messages: Membrane

313596:RB2501 RS00265
gene id: 313596:RB2501_RS00265
uniprot id: A4CG83
names: Similarity
messages: Belongs to the SCO1/2 family.

313596:RB2501 RS11890
gene id: 313596:RB2501_RS11890
uniprot id: A4CLL8
names: Similarity
messages: Belongs to the ArsC family.

313596:RB2501 RS04880
gene id: 313596:RB2501_RS04880
uniprot id: A4CIX9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell inner membrane
messages: Membrane

313596:RB2501 RS00305
gene id: 313596:RB2501_RS00305
uniprot id: A4CG92
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

313596:RB2501 RS14990
gene id: 313596:RB2501_RS14990
uniprot id: A4CPF8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrF family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Cell inner membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway.

313596:RB2501 RS06435
gene id: 313596:RB2501_RS06435
uniprot id: A4CJU2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

313596:RB2501 RS04720
gene id: 313596:RB2501_RS04720
uniprot id: A4CIU7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

313596:RB2501 RS09730
gene id: 313596:RB2501_RS09730
uniprot id: A4CKA8
names: Caution
names: Function
names: Similarity
messages: Belongs to the APS kinase family.
messages: Catalyzes the synthesis of activated sulfate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

313596:RB2501 RS08855
gene id: 313596:RB2501_RS08855
uniprot id: A4CN85
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

313596:RB2501 RS15095
gene id: 313596:RB2501_RS15095
uniprot id: A4CPI1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

313596:RB2501 RS09345
gene id: 313596:RB2501_RS09345
uniprot id: A4CK30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

313596:RB2501 RS10665
gene id: 313596:RB2501_RS10665
uniprot id: A4CKW0
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

313596:RB2501 RS15240
gene id: 313596:RB2501_RS15240
uniprot id: A4CPL1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

313596:RB2501 RS05515
gene id: 313596:RB2501_RS05515
uniprot id: A4CJA9
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

313596:RB2501 RS04185
gene id: 313596:RB2501_RS04185
uniprot id: A4CII7
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.

313596:RB2501 RS12430
gene id: 313596:RB2501_RS12430
uniprot id: A4CLX9
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

313596:RB2501 RS15510
gene id: 313596:RB2501_RS15510
uniprot id: A4CPR8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

313596:RB2501 RS03410
gene id: 313596:RB2501_RS03410
uniprot id: A4CI31
names: Similarity
messages: Belongs to the Skp family.

313596:RB2501 RS11400
gene id: 313596:RB2501_RS11400
uniprot id: A4CLB3
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

313596:RB2501 RS15085
gene id: 313596:RB2501_RS15085
uniprot id: A4CPH9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.

313596:RB2501 RS07625
gene id: 313596:RB2501_RS07625
uniprot id: A4CMH7
names: Caution
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IcmF family.
messages: Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly.
messages: Homodimer.
messages: Is composed of four functional domains: the N-terminal 5'-deoxyadenosylcobalamin binding region that is homologous to the small subunit of ICM (IcmB), a middle P-loop GTPase domain (MeaI) that likely acts as a chaperone for ICM, a structured linker region involved in dimer formation, and a C-terminal part that is homologous to the large substrate-binding subunit of ICM (IcmA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

313596:RB2501 RS02430
gene id: 313596:RB2501_RS02430
uniprot id: A4CHH1
names: Similarity
messages: Belongs to the hyi family.

313596:RB2501 RS07660
gene id: 313596:RB2501_RS07660
uniprot id: A4CMI4
names: Similarity
messages: Belongs to the P(II) protein family.

313596:RB2501 RS11780
gene id: 313596:RB2501_RS11780
uniprot id: A4CLJ3
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

313596:RB2501 RS11495
gene id: 313596:RB2501_RS11495
uniprot id: A4CLD2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

313596:RB2501 RS02255
gene id: 313596:RB2501_RS02255
uniprot id: A4CHD5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

313596:RB2501 RS09215
gene id: 313596:RB2501_RS09215
uniprot id: A4CK04
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

313596:RB2501 RS07105
gene id: 313596:RB2501_RS07105
uniprot id: A4CM72
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

313596:RB2501 RS04180
gene id: 313596:RB2501_RS04180
uniprot id: A4CII6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

313596:RB2501 RS10690
gene id: 313596:RB2501_RS10690
uniprot id: A4CKW5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

313596:RB2501 RS10480
gene id: 313596:RB2501_RS10480
uniprot id: A4CKR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Membrane

313596:RB2501 RS02270
gene id: 313596:RB2501_RS02270
uniprot id: A4CHD8
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

313596:RB2501 RS06315
gene id: 313596:RB2501_RS06315
uniprot id: A4CJR8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

313596:RB2501 RS13525
gene id: 313596:RB2501_RS13525
uniprot id: A4CP12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

313596:RB2501 RS14875
gene id: 313596:RB2501_RS14875
uniprot id: A4CPD5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the kynureninase family.
messages: Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

313596:RB2501 RS02680
gene id: 313596:RB2501_RS02680
uniprot id: A4CHM3
names: Function
names: Similarity
messages: Belongs to the HMBS family.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.

313596:RB2501 RS00475
gene id: 313596:RB2501_RS00475
uniprot id: A4CGC7
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.

313596:RB2501 RS12900
gene id: 313596:RB2501_RS12900
uniprot id: A4CNN4
names: Subcellular Location Annotation
messages: Secreted

313596:RB2501 RS09080
gene id: 313596:RB2501_RS09080
uniprot id: A4CND2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

313596:RB2501 RS01245
gene id: 313596:RB2501_RS01245
uniprot id: A4CGT2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

313596:RB2501 RS12275
gene id: 313596:RB2501_RS12275
uniprot id: A4CLU8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

313596:RB2501 RS00665
gene id: 313596:RB2501_RS00665
uniprot id: A4CGG5
names: Subcellular Location Annotation
messages: Membrane

313596:RB2501 RS05775
gene id: 313596:RB2501_RS05775
uniprot id: A4CJG2
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

313596:RB2501 RS09800
gene id: 313596:RB2501_RS09800
uniprot id: A4CKC2
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

313596:RB2501 RS03705
gene id: 313596:RB2501_RS03705
uniprot id: A4CI90
names: Similarity
messages: Belongs to the Nudix hydrolase family.

313596:RB2501 RS15530
gene id: 313596:RB2501_RS15530
uniprot id: A4CPS2
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-stimulated subfamily.
messages: Cell inner membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Requires K(+) for maximal activity.
messages: Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na(+) movement across the membrane.

313596:RB2501 RS09590
gene id: 313596:RB2501_RS09590
uniprot id: A4CK77
names: Similarity
messages: Belongs to the SusD family.

313596:RB2501 RS12715
gene id: 313596:RB2501_RS12715
uniprot id: A4CNJ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

313596:RB2501 RS04865
gene id: 313596:RB2501_RS04865
uniprot id: A4CIX6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

313596:RB2501 RS04655
gene id: 313596:RB2501_RS04655
uniprot id: A4CIT4
names: Cofactor
names: Function
names: Similarity
messages: Adenine glycosylase active on G-A mispairs.
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.

313596:RB2501 RS11500
gene id: 313596:RB2501_RS11500
uniprot id: A4CLD3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

313596:RB2501 RS04370
gene id: 313596:RB2501_RS04370
uniprot id: A4CIM5
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

313596:RB2501 RS12705
gene id: 313596:RB2501_RS12705
uniprot id: A4CNJ0
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

313596:RB2501 RS06550
gene id: 313596:RB2501_RS06550
uniprot id: A4CJW6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

313596:RB2501 RS14335
gene id: 313596:RB2501_RS14335
uniprot id: A4CQ62
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

313596:RB2501 RS05180
gene id: 313596:RB2501_RS05180
uniprot id: A4CJ40
names: Similarity
messages: Belongs to the glycosyl hydrolase 65 family.

313596:RB2501 RS02595
gene id: 313596:RB2501_RS02595
uniprot id: A4CHK6
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.

313596:RB2501 RS07600
gene id: 313596:RB2501_RS07600
uniprot id: A4CMH2
names: Similarity
messages: Belongs to the SusD family.

313596:RB2501 RS11805
gene id: 313596:RB2501_RS11805
uniprot id: A4CLK0
names: Subcellular Location Annotation
messages: Membrane

313596:RB2501 RS00065
gene id: 313596:RB2501_RS00065
uniprot id: A4CG43
names: Similarity
messages: Belongs to the peptidase S49 family.

313596:RB2501 RS12875
gene id: 313596:RB2501_RS12875
uniprot id: A4CNM9
names: Similarity
messages: Belongs to the group II decarboxylase family.

313596:RB2501 RS04965
gene id: 313596:RB2501_RS04965
uniprot id: A4CIZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

313596:RB2501 RS07015
gene id: 313596:RB2501_RS07015
uniprot id: A4CM56
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell inner membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

313596:RB2501 RS09310
gene id: 313596:RB2501_RS09310
uniprot id: A4CK23
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

313596:RB2501 RS02475
gene id: 313596:RB2501_RS02475
uniprot id: A4CHI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell inner membrane
messages: Membrane

313596:RB2501 RS07470
gene id: 313596:RB2501_RS07470
uniprot id: A4CME6
names: Subcellular Location Annotation
messages: Membrane

313596:RB2501 RS09210
gene id: 313596:RB2501_RS09210
uniprot id: A4CK03
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase Z family.
messages: Binds 2 Zn(2+) ions.
messages: Homodimer.
messages: Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.

313596:RB2501 RS11265
gene id: 313596:RB2501_RS11265
uniprot id: A4CL83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

313596:RB2501 RS00020
gene id: 313596:RB2501_RS00020
uniprot id: A4CG34
names: Caution
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

313596:RB2501 RS15245
gene id: 313596:RB2501_RS15245
uniprot id: A4CPL2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell inner membrane
messages: Membrane

313596:RB2501 RS00660
gene id: 313596:RB2501_RS00660
uniprot id: A4CGG4
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

313596:RB2501 RS10780
gene id: 313596:RB2501_RS10780
uniprot id: A4CKY3
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

313596:RB2501 RS05260
gene id: 313596:RB2501_RS05260
uniprot id: A4CJ56
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

313596:RB2501 RS05735
gene id: 313596:RB2501_RS05735
uniprot id: A4CJF4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell inner membrane
messages: Cytoplasm
messages: Monomer.

313596:RB2501 RS03075
gene id: 313596:RB2501_RS03075
uniprot id: A4CHV9
names: Function
names: Similarity
messages: Belongs to the TrhO family.
messages: Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.

313596:RB2501 RS04520
gene id: 313596:RB2501_RS04520
uniprot id: A4CIQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

313596:RB2501 RS11085
gene id: 313596:RB2501_RS11085
uniprot id: A4CL44
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

313596:RB2501 RS00360
gene id: 313596:RB2501_RS00360
uniprot id: A4CGA5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.
messages: Belongs to the acyl-CoA oxidase family.

313596:RB2501 RS06960
gene id: 313596:RB2501_RS06960
uniprot id: A4CM46
names: Similarity
messages: Belongs to the asparagine synthetase family.

313596:RB2501 RS10720
gene id: 313596:RB2501_RS10720
uniprot id: A4CKX1
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

313596:RB2501 RS12465
gene id: 313596:RB2501_RS12465
uniprot id: A4CLY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0073 (Hly-III) family.
messages: Membrane

313596:RB2501 RS09485
gene id: 313596:RB2501_RS09485
uniprot id: A4CK57
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

313596:RB2501 RS05525
gene id: 313596:RB2501_RS05525
uniprot id: A4CJB1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

313596:RB2501 RS15065
gene id: 313596:RB2501_RS15065
uniprot id: A4CPH5
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).

313596:RB2501 RS15100
gene id: 313596:RB2501_RS15100
uniprot id: A4CPI2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

313596:RB2501 RS04285
gene id: 313596:RB2501_RS04285
uniprot id: A4CIK8
names: Similarity
names: Subunit
messages: Belongs to the aldehyde dehydrogenase family.
messages: Homotetramer.

313596:RB2501 RS14980
gene id: 313596:RB2501_RS14980
uniprot id: A4CPF6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ApbE family.
messages: Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.
messages: Magnesium. Can also use manganese.

313596:RB2501 RS13510
gene id: 313596:RB2501_RS13510
uniprot id: A4CP10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

313596:RB2501 RS13190
gene id: 313596:RB2501_RS13190
uniprot id: A4CNU4
names: Subcellular Location Annotation
messages: Membrane

313596:RB2501 RS12510
gene id: 313596:RB2501_RS12510
uniprot id: A4CQA7
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

313596:RB2501 RS15340
gene id: 313596:RB2501_RS15340
uniprot id: A4CPN3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

313596:RB2501 RS00825
gene id: 313596:RB2501_RS00825
uniprot id: A4CGJ7
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

313596:RB2501 RS08165
gene id: 313596:RB2501_RS08165
uniprot id: A4CMU0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell inner membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

313596:RB2501 RS14070
gene id: 313596:RB2501_RS14070
uniprot id: A4CQ07
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

313596:RB2501 RS05485
gene id: 313596:RB2501_RS05485
uniprot id: A4CJA3
names: Similarity
messages: Belongs to the DNA/RNA non-specific endonuclease family.

313596:RB2501 RS04415
gene id: 313596:RB2501_RS04415
uniprot id: A4CIN4
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

313596:RB2501 RS14065
gene id: 313596:RB2501_RS14065
uniprot id: A4CQ06
names: Subcellular Location Annotation
messages: Membrane

313596:RB2501 RS14615
gene id: 313596:RB2501_RS14615
uniprot id: A4CP80
names: Similarity
messages: Belongs to the TrpF family.

313596:RB2501 RS13230
gene id: 313596:RB2501_RS13230
uniprot id: A4CNV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

313596:RB2501 RS14455
gene id: 313596:RB2501_RS14455
uniprot id: A4CQ89
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

313596:RB2501 RS11995
gene id: 313596:RB2501_RS11995
uniprot id: A4CLP1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MenA family. Type 1 subfamily.
messages: Cell inner membrane
messages: Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

313596:RB2501 RS15175
gene id: 313596:RB2501_RS15175
uniprot id: A4CPJ8
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

313596:RB2501 RS04130
gene id: 313596:RB2501_RS04130
uniprot id: A4CIH6
names: Caution
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

313596:RB2501 RS01020
gene id: 313596:RB2501_RS01020
uniprot id: A4CGN6
names: Similarity
messages: Belongs to the HupF/HypC family.

313596:RB2501 RS04625
gene id: 313596:RB2501_RS04625
uniprot id: A4CIS8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

313596:RB2501 RS10185
gene id: 313596:RB2501_RS10185
uniprot id: A4CKK2
names: Subcellular Location Annotation
messages: Membrane

313596:RB2501 RS01115
gene id: 313596:RB2501_RS01115
uniprot id: A4CGQ7
names: Function
names: Similarity
messages: Belongs to the peptidase S9C family.
messages: This enzyme catalyzes the hydrolysis of the N-terminal peptide bond of an N-acetylated peptide to generate an N-acetylated amino acid and a peptide with a free N-terminus. It preferentially cleaves off Ac-Ala, Ac-Met and Ac-Ser.

313596:RB2501 RS05175
gene id: 313596:RB2501_RS05175
uniprot id: A4CJ39
names: Cofactor
messages: Binds 2 magnesium ions per subunit.

313596:RB2501 RS14665
gene id: 313596:RB2501_RS14665
uniprot id: A4CP92
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

313596:RB2501 RS04340
gene id: 313596:RB2501_RS04340
uniprot id: A4CIL9
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.

313596:RB2501 RS06220
gene id: 313596:RB2501_RS06220
uniprot id: A4CJP9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 2 lipoyl cofactors covalently.
messages: Forms a 24-polypeptide structural core with octahedral symmetry.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

313596:RB2501 RS03725
gene id: 313596:RB2501_RS03725
uniprot id: A4CI94
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

313596:RB2501 RS03840
gene id: 313596:RB2501_RS03840
uniprot id: A4CIB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

313596:RB2501 RS15380
gene id: 313596:RB2501_RS15380
uniprot id: A4CPP2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

313596:RB2501 RS12895
gene id: 313596:RB2501_RS12895
uniprot id: A4CNN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM175 family.
messages: Membrane

313596:RB2501 RS15005
gene id: 313596:RB2501_RS15005
uniprot id: A4CPG1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrC family.
messages: Cell inner membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

313596:RB2501 RS00465
gene id: 313596:RB2501_RS00465
uniprot id: A4CGC5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CutC family.
messages: Cytoplasm
messages: Once thought to be involved in copper homeostasis, experiments in E.coli have shown this is not the case.

313596:RB2501 RS00510
gene id: 313596:RB2501_RS00510
uniprot id: A4CGD4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

313596:RB2501 RS11525
gene id: 313596:RB2501_RS11525
uniprot id: A4CLD8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

313596:RB2501 RS08220
gene id: 313596:RB2501_RS08220
uniprot id: A4CMV2
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

313596:RB2501 RS03505
gene id: 313596:RB2501_RS03505
uniprot id: A4CI49
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

313596:RB2501 RS05020
gene id: 313596:RB2501_RS05020
uniprot id: A4CJ08
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the ferredoxin--NADP reductase type 2 family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

313596:RB2501 RS03315
gene id: 313596:RB2501_RS03315
uniprot id: A4CI10
names: Subcellular Location Annotation
messages: Membrane

313596:RB2501 RS06280
gene id: 313596:RB2501_RS06280
uniprot id: A4CJR1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

313596:RB2501 RS13625
gene id: 313596:RB2501_RS13625
uniprot id: A4CP31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the etk/wzc family.
messages: Cell inner membrane
messages: Membrane

313596:RB2501 RS04635
gene id: 313596:RB2501_RS04635
uniprot id: A4CIT0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

313596:RB2501 RS10705
gene id: 313596:RB2501_RS10705
uniprot id: A4CKW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

313596:RB2501 RS07415
gene id: 313596:RB2501_RS07415
uniprot id: A4CMD5
names: Similarity
messages: Belongs to the nitroreductase family.

313596:RB2501 RS04430
gene id: 313596:RB2501_RS04430
uniprot id: A4CIN8
names: Cofactor
names: Similarity
messages: Belongs to the 4HPPD family.
messages: Binds 1 Fe cation per subunit.

313596:RB2501 RS02665
gene id: 313596:RB2501_RS02665
uniprot id: A4CHM0
names: Subunit
messages: Homodimer.

313596:RB2501 RS03990
gene id: 313596:RB2501_RS03990
uniprot id: A4CIE8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

313596:RB2501 RS14830
gene id: 313596:RB2501_RS14830
uniprot id: A4CPC6
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

313596:RB2501 RS04575
gene id: 313596:RB2501_RS04575
uniprot id: A4CIR7
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

313596:RB2501 RS05510
gene id: 313596:RB2501_RS05510
uniprot id: A4CJA8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

313596:RB2501 RS03055
gene id: 313596:RB2501_RS03055
uniprot id: A4CHV5
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit A family.

313596:RB2501 RS08325
gene id: 313596:RB2501_RS08325
uniprot id: A4CMX4
names: Similarity
messages: Belongs to the sterol desaturase family.

313596:RB2501 RS11420
gene id: 313596:RB2501_RS11420
uniprot id: A4CLB7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

313596:RB2501 RS05835
gene id: 313596:RB2501_RS05835
uniprot id: A4CJH6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

313596:RB2501 RS12625
gene id: 313596:RB2501_RS12625
uniprot id: A4CNH3
names: Caution
names: Function
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the 2'-O methylation of guanosine at position 18 in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

313596:RB2501 RS15625
gene id: 313596:RB2501_RS15625
uniprot id: A4CPU1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

313596:RB2501 RS04860
gene id: 313596:RB2501_RS04860
uniprot id: A4CIX5
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

313596:RB2501 RS13135
gene id: 313596:RB2501_RS13135
uniprot id: A4CNT3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

313596:RB2501 RS04410
gene id: 313596:RB2501_RS04410
uniprot id: A4CIN3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

313596:RB2501 RS06445
gene id: 313596:RB2501_RS06445
uniprot id: A4CJU4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

313596:RB2501 RS05530
gene id: 313596:RB2501_RS05530
uniprot id: A4CJB2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

313596:RB2501 RS08415
gene id: 313596:RB2501_RS08415
uniprot id: A4CMZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

313596:RB2501 RS12015
gene id: 313596:RB2501_RS12015
uniprot id: A4CLP5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TPP enzyme family. MenD subfamily.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
messages: Homodimer.

313596:RB2501 RS09130
gene id: 313596:RB2501_RS09130
uniprot id: A4CNE3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

313596:RB2501 RS04775
gene id: 313596:RB2501_RS04775
uniprot id: A4CIV8
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

313596:RB2501 RS01605
gene id: 313596:RB2501_RS01605
uniprot id: A4CH03
names: Subcellular Location Annotation
messages: Endosome membrane
messages: Membrane

313596:RB2501 RS06170
gene id: 313596:RB2501_RS06170
uniprot id: A4CJP0
names: Similarity
messages: Belongs to the universal stress protein A family.

313596:RB2501 RS01595
gene id: 313596:RB2501_RS01595
uniprot id: A4CH01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

313596:RB2501 RS14400
gene id: 313596:RB2501_RS14400
uniprot id: A4CQ76
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

313596:RB2501 RS05270
gene id: 313596:RB2501_RS05270
uniprot id: A4CJ58
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

313596:RB2501 RS14950
gene id: 313596:RB2501_RS14950
uniprot id: A4CPE9
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

313596:RB2501 RS03090
gene id: 313596:RB2501_RS03090
uniprot id: A4CHW3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

313596:RB2501 RS12885
gene id: 313596:RB2501_RS12885
uniprot id: A4CNN1
names: Similarity
names: Subunit
messages: Belongs to the glycosyltransferase 20 family.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the trehalose phosphatase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 20 family.

313596:RB2501 RS02105
gene id: 313596:RB2501_RS02105
uniprot id: A4CHA4
names: Cofactor
names: Similarity
messages: Belongs to the peptidase S45 family.
messages: Binds 1 Ca(2+) ion per dimer.

313596:RB2501 RS00355
gene id: 313596:RB2501_RS00355
uniprot id: A4CGA4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Cytoplasm
messages: Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.

313596:RB2501 RS03545
gene id: 313596:RB2501_RS03545
uniprot id: A4CI58
names: Similarity
messages: Belongs to the fructosamine kinase family.

313596:RB2501 RS10800
gene id: 313596:RB2501_RS10800
uniprot id: A4CKY7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

313596:RB2501 RS12110
gene id: 313596:RB2501_RS12110
uniprot id: A4CLR4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 3B subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

313596:RB2501 RS14825
gene id: 313596:RB2501_RS14825
uniprot id: A4CPC5
names: Function
names: Similarity
messages: Belongs to the LpxK family.
messages: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

313596:RB2501 RS14195
gene id: 313596:RB2501_RS14195
uniprot id: A4CQ34
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

313596:RB2501 RS08900
gene id: 313596:RB2501_RS08900
uniprot id: A4CN95
names: Cofactor
names: Similarity
messages: Belongs to the monomeric-type IDH family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

313596:RB2501 RS03350
gene id: 313596:RB2501_RS03350
uniprot id: A4CI17
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

313596:RB2501 RS02400
gene id: 313596:RB2501_RS02400
uniprot id: A4CHG5
names: Subcellular Location Annotation
messages: Membrane

313596:RB2501 RS02095
gene id: 313596:RB2501_RS02095
uniprot id: A4CHA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

313596:RB2501 RS00540
gene id: 313596:RB2501_RS00540
uniprot id: A4CGE0
names: Similarity
messages: Belongs to the sigma-54 factor family.

313596:RB2501 RS03635
gene id: 313596:RB2501_RS03635
uniprot id: A4CI77
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

313596:RB2501 RS02715
gene id: 313596:RB2501_RS02715
uniprot id: A4CHN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.
messages: Cell membrane

313596:RB2501 RS06885
gene id: 313596:RB2501_RS06885
uniprot id: A4CM31
names: Subunit
messages: Monomer.

313596:RB2501 RS09380
gene id: 313596:RB2501_RS09380
uniprot id: A4CK37
names: Similarity
names: Subunit
messages: Homotetramer.
messages: In the C-terminal section; belongs to the homoserine dehydrogenase family.
messages: In the N-terminal section; belongs to the aspartokinase family.

313596:RB2501 RS00495
gene id: 313596:RB2501_RS00495
uniprot id: A4CGD1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

313596:RB2501 RS09920
gene id: 313596:RB2501_RS09920
uniprot id: A4CKE8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

313596:RB2501 RS13045
gene id: 313596:RB2501_RS13045
uniprot id: A4CNR3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

313596:RB2501 RS02585
gene id: 313596:RB2501_RS02585
uniprot id: A4CHK4
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

313596:RB2501 RS03555
gene id: 313596:RB2501_RS03555
uniprot id: A4CI60
names: Similarity
messages: Belongs to the peptidase S41A family.

313596:RB2501 RS04605
gene id: 313596:RB2501_RS04605
uniprot id: A4CIS4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

313596:RB2501 RS02305
gene id: 313596:RB2501_RS02305
uniprot id: A4CHE5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

313596:RB2501 RS08895
gene id: 313596:RB2501_RS08895
uniprot id: A4CN94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

313596:RB2501 RS05240
gene id: 313596:RB2501_RS05240
uniprot id: A4CJ52
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

313596:RB2501 RS08280
gene id: 313596:RB2501_RS08280
uniprot id: A4CMW5
names: Function
names: Similarity
messages: Belongs to the RNase Y family.
messages: Endoribonuclease that initiates mRNA decay.

313596:RB2501 RS15535
gene id: 313596:RB2501_RS15535
uniprot id: A4CPS3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

313596:RB2501 RS03100
gene id: 313596:RB2501_RS03100
uniprot id: A4CHW5
names: Domain
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

313596:RB2501 RS05475
gene id: 313596:RB2501_RS05475
uniprot id: A4CJA1
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

313596:RB2501 RS04175
gene id: 313596:RB2501_RS04175
uniprot id: A4CII5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

313596:RB2501 RS08990
gene id: 313596:RB2501_RS08990
uniprot id: A4CNB4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell inner membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

313596:RB2501 RS02550
gene id: 313596:RB2501_RS02550
uniprot id: A4CHJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the branched chain amino acid transporter family.
messages: Membrane

313596:RB2501 RS09050
gene id: 313596:RB2501_RS09050
uniprot id: A4CNC6
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

313596:RB2501 RS00200
gene id: 313596:RB2501_RS00200
uniprot id: A4CG70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

313596:RB2501 RS14445
gene id: 313596:RB2501_RS14445
uniprot id: A4CQ87
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

313596:RB2501 RS10775
gene id: 313596:RB2501_RS10775
uniprot id: A4CKY2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

313596:RB2501 RS03620
gene id: 313596:RB2501_RS03620
uniprot id: A4CI74
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

313596:RB2501 RS10640
gene id: 313596:RB2501_RS10640
uniprot id: A4CKV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Membrane

313596:RB2501 RS07555
gene id: 313596:RB2501_RS07555
uniprot id: A4CMG3
names: Similarity
messages: Belongs to the glutamine synthetase family.

313596:RB2501 RS13575
gene id: 313596:RB2501_RS13575
uniprot id: A4CP21
names: Subcellular Location Annotation
messages: Membrane

313596:RB2501 RS14690
gene id: 313596:RB2501_RS14690
uniprot id: A4CP97
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

313596:RB2501 RS10625
gene id: 313596:RB2501_RS10625
uniprot id: A4CKV2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.
messages: In the N-terminal section; belongs to the DHBP synthase family.

313596:RB2501 RS07860
gene id: 313596:RB2501_RS07860
uniprot id: A4CMM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

313596:RB2501 RS04870
gene id: 313596:RB2501_RS04870
uniprot id: A4CIX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

313596:RB2501 RS01415
gene id: 313596:RB2501_RS01415
uniprot id: A4CGW5
names: Subcellular Location Annotation
messages: Membrane

313596:RB2501 RS06480
gene id: 313596:RB2501_RS06480
uniprot id: A4CJV1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

313596:RB2501 RS03175
gene id: 313596:RB2501_RS03175
uniprot id: A4CHY1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell inner membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

313596:RB2501 RS15210
gene id: 313596:RB2501_RS15210
uniprot id: A4CPK5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

313596:RB2501 RS15125
gene id: 313596:RB2501_RS15125
uniprot id: A4CPI8
names: Similarity
messages: Belongs to the UPF0057 (PMP3) family.

313596:RB2501 RS05160
gene id: 313596:RB2501_RS05160
uniprot id: A4CJ36
names: Similarity
messages: Belongs to the SusD family.

313596:RB2501 RS01295
gene id: 313596:RB2501_RS01295
uniprot id: A4CGU2
names: Subcellular Location Annotation
messages: Membrane

313596:RB2501 RS04585
gene id: 313596:RB2501_RS04585
uniprot id: A4CIS0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

313596:RB2501 RS06035
gene id: 313596:RB2501_RS06035
uniprot id: A4CJL3
names: Similarity
messages: Belongs to the peptidase U62 family.

313596:RB2501 RS06485
gene id: 313596:RB2501_RS06485
uniprot id: A4CJV2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

313596:RB2501 RS15010
gene id: 313596:RB2501_RS15010
uniprot id: A4CPG2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell inner membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

313596:RB2501 RS07040
gene id: 313596:RB2501_RS07040
uniprot id: A4CM61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

313596:RB2501 RS12245
gene id: 313596:RB2501_RS12245
uniprot id: A4CLU2
names: Similarity
messages: Belongs to the gluconokinase GntK/GntV family.

313596:RB2501 RS05935
gene id: 313596:RB2501_RS05935
uniprot id: A4CJJ3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

313596:RB2501 RS04620
gene id: 313596:RB2501_RS04620
uniprot id: A4CIS7
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

313596:RB2501 RS01615
gene id: 313596:RB2501_RS01615
uniprot id: A4CH05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

313596:RB2501 RS06310
gene id: 313596:RB2501_RS06310
uniprot id: A4CJR7
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

313596:RB2501 RS09045
gene id: 313596:RB2501_RS09045
uniprot id: A4CNC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

313596:RB2501 RS03375
gene id: 313596:RB2501_RS03375
uniprot id: A4CI22
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell inner membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

313596:RB2501 RS03080
gene id: 313596:RB2501_RS03080
uniprot id: A4CHW1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

313596:RB2501 RS12455
gene id: 313596:RB2501_RS12455
uniprot id: A4CLY4
names: Subcellular Location Annotation
messages: Membrane

313596:RB2501 RS07920
gene id: 313596:RB2501_RS07920
uniprot id: A4CMP1
names: Subcellular Location Annotation
messages: Membrane

313596:RB2501 RS07050
gene id: 313596:RB2501_RS07050
uniprot id: A4CM63
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.
messages: Cytoplasm
messages: Homodimer.

313596:RB2501 RS06425
gene id: 313596:RB2501_RS06425
uniprot id: A4CJU0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

313596:RB2501 RS05930
gene id: 313596:RB2501_RS05930
uniprot id: A4CJJ2
names: Similarity
messages: Belongs to the glutamate synthase family.

313596:RB2501 RS05450
gene id: 313596:RB2501_RS05450
uniprot id: A4CJ96
names: Similarity
messages: Belongs to the peptidase C40 family.

313596:RB2501 RS12060
gene id: 313596:RB2501_RS12060
uniprot id: A4CLQ4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

313596:RB2501 RS11455
gene id: 313596:RB2501_RS11455
uniprot id: A4CLC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

313596:RB2501 RS15615
gene id: 313596:RB2501_RS15615
uniprot id: A4CPT9
names: Similarity
messages: Belongs to the Skp family.

313596:RB2501 RS15110
gene id: 313596:RB2501_RS15110
uniprot id: A4CPI5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

313596:RB2501 RS00815
gene id: 313596:RB2501_RS00815
uniprot id: A4CGJ4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the arginase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide.

313596:RB2501 RS06630
gene id: 313596:RB2501_RS06630
uniprot id: A4CJY3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

313596:RB2501 RS12365
gene id: 313596:RB2501_RS12365
uniprot id: A4CLW6
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

313596:RB2501 RS03925
gene id: 313596:RB2501_RS03925
uniprot id: A4CID5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

313596:RB2501 RS14550
gene id: 313596:RB2501_RS14550
uniprot id: A4CP67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

313596:RB2501 RS15000
gene id: 313596:RB2501_RS15000
uniprot id: A4CPG0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Membrane
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

313596:RB2501 RS09385
gene id: 313596:RB2501_RS09385
uniprot id: A4CK38
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

313596:RB2501 RS14555
gene id: 313596:RB2501_RS14555
uniprot id: A4CP68
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

313596:RB2501 RS08765
gene id: 313596:RB2501_RS08765
uniprot id: A4CN68
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

313596:RB2501 RS09360
gene id: 313596:RB2501_RS09360
uniprot id: A4CK33
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

313596:RB2501 RS12800
gene id: 313596:RB2501_RS12800
uniprot id: A4CNL3
names: Similarity
messages: Belongs to the phosphohexose mutase family.

313596:RB2501 RS08335
gene id: 313596:RB2501_RS08335
uniprot id: A4CMX6
names: Similarity
messages: Belongs to the carotenoid/retinoid oxidoreductase family.

313596:RB2501 RS02600
gene id: 313596:RB2501_RS02600
uniprot id: A4CHK7
names: Similarity
messages: Belongs to the SufE family.

313596:RB2501 RS00230
gene id: 313596:RB2501_RS00230
uniprot id: A4CG76
names: Subcellular Location Annotation
messages: Membrane

313596:RB2501 RS06520
gene id: 313596:RB2501_RS06520
uniprot id: A4CJV9
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

313596:RB2501 RS09455
gene id: 313596:RB2501_RS09455
uniprot id: A4CK51
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Atypical ATP-dependent clade 'X' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homodimer.

313596:RB2501 RS02440
gene id: 313596:RB2501_RS02440
uniprot id: A4CHH5
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.

313596:RB2501 RS00240
gene id: 313596:RB2501_RS00240
uniprot id: A4CG78
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

313596:RB2501 RS12375
gene id: 313596:RB2501_RS12375
uniprot id: A4CLW8
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

313596:RB2501 RS08210
gene id: 313596:RB2501_RS08210
uniprot id: A4CMV0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell inner membrane
messages: Forms a complex with TatA.
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.

313596:RB2501 RS08175
gene id: 313596:RB2501_RS08175
uniprot id: A4CMU2
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

313596:RB2501 RS08130
gene id: 313596:RB2501_RS08130
uniprot id: A4CMT2
names: Subcellular Location Annotation
messages: Membrane

313596:RB2501 RS05760
gene id: 313596:RB2501_RS05760
uniprot id: A4CJF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

313596:RB2501 RS11070
gene id: 313596:RB2501_RS11070
uniprot id: A4CL41
names: Similarity
messages: Belongs to the thiolase-like superfamily. Chalcone/stilbene synthases family.

313596:RB2501 RS08060
gene id: 313596:RB2501_RS08060
uniprot id: A4CMR8
names: Subcellular Location Annotation
messages: Membrane

313596:RB2501 RS12175
gene id: 313596:RB2501_RS12175
uniprot id: A4CLS7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

313596:RB2501 RS04060
gene id: 313596:RB2501_RS04060
uniprot id: A4CIG2
names: Subcellular Location Annotation
messages: Membrane

313596:RB2501 RS07290
gene id: 313596:RB2501_RS07290
uniprot id: A4CMB0
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

313596:RB2501 RS09630
gene id: 313596:RB2501_RS09630
uniprot id: A4CK88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

313596:RB2501 RS09005
gene id: 313596:RB2501_RS09005
uniprot id: A4CNB7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.