31033:LOC101079404
gene id: 31033:LOC101079404
uniprot id: H2S926
names: Similarity
messages: Belongs to the DSD1 family.

31033:nt5c3b
gene id: 31033:nt5c3b
uniprot id: A0A3B5KKE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrimidine 5'-nucleotidase family.
messages: Cytoplasm

31033:LOC101064999
gene id: 31033:LOC101064999
uniprot id: H2S8L2
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

31033:tmem234
gene id: 31033:tmem234
uniprot id: A0A674MGI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM234 family.
messages: Membrane

31033:adi1
gene id: 31033:adi1
uniprot id: H2SK08
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acireductone dioxygenase (ARD) family.
messages: Binds either 1 Fe or Ni cation per monomer. Iron-binding promotes an acireductone dioxygenase reaction producing 2-keto-4-methylthiobutyrate, while nickel-binding promotes an acireductone dioxygenase reaction producing 3-(methylsulfanyl)propanoate.
messages: Catalyzes 2 different reactions between oxygen and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.
messages: Nucleus

31033:LOC101061942
gene id: 31033:LOC101061942
uniprot id: H2T1L6
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

31033:LOC101063424
gene id: 31033:LOC101063424
uniprot id: H2V5J8
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

31033:med30
gene id: 31033:med30
uniprot id: H2S969
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 30 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Nucleus

31033:mrps18a
gene id: 31033:mrps18a
uniprot id: A0A674P6F3
names: Subcellular Location Annotation
messages: Mitochondrion

31033:atp6v1d
gene id: 31033:atp6v1d
uniprot id: A0A3B5K8V3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase D subunit family.
messages: clathrin-coated vesicle membrane

31033:scn1b
gene id: 31033:scn1b
uniprot id: A0A674NBA5
names: Subcellular Location Annotation
messages: Membrane

31033:ak2
gene id: 31033:ak2
uniprot id: H2RRV5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family. AK2 subfamily.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways. Plays a key role in hematopoiesis.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Mitochondrion intermembrane space
messages: Monomer.

31033:LOC101078191
gene id: 31033:LOC101078191
uniprot id: A0A674NKY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SYG1 (TC 2.A.94) family.
messages: Membrane

31033:rars2
gene id: 31033:rars2
uniprot id: H2V8R5
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

31033:LOC101077703
gene id: 31033:LOC101077703
uniprot id: A0A674N037
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gastrin/cholecystokinin family.
messages: Secreted

31033:LOC101065186
gene id: 31033:LOC101065186
uniprot id: A0A674MZB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

31033:LOC101076426
gene id: 31033:LOC101076426
uniprot id: A0A674P1G9
names: Similarity
messages: Belongs to the S-100 family.

31033:yars2
gene id: 31033:yars2
uniprot id: H2UYT1
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

31033:LOC101078850
gene id: 31033:LOC101078850
uniprot id: H2V208
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM208 family.
messages: Endoplasmic reticulum membrane
messages: May function as a negative regulator of endoplasmic reticulum-stress induced autophagy.
messages: Membrane

31033:s100z
gene id: 31033:s100z
uniprot id: A0A674PBZ5
names: Similarity
messages: Belongs to the S-100 family.

31033:ccdc167
gene id: 31033:ccdc167
uniprot id: A0A3B5KIM7
names: Subcellular Location Annotation
messages: Membrane

31033:tph1
gene id: 31033:tph1
uniprot id: Q6IWN2
names: Similarity
messages: Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.

31033:LOC100653419
gene id: 31033:LOC100653419
uniprot id: E9LZ00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prominin family.
messages: Membrane
messages: microvillus membrane

31033:c9
gene id: 31033:c9
uniprot id: P79755
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complement C6/C7/C8/C9 family.
messages: Component of the membrane attack complex (MAC). About 20 C9 chains oligomerize to give rise to a huge beta-barrel that forms a 100 Angstrom diameter pore in target membranes.
messages: Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells. C9 is the pore-forming subunit of the MAC.
messages: Secreted
messages: Target cell membrane
messages: The structure of the human polymeric form indicates the existence of an additional disulfide bond compared to the mouse monomeric form.

31033:mmp9
gene id: 31033:mmp9
uniprot id: Q4JF83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M10A family.
messages: extracellular matrix

31033:agrp1
gene id: 31033:agrp1
uniprot id: A0ZSG6
names: Subcellular Location Annotation
messages: Secreted

31033:fgc6ast2
gene id: 31033:fgc6ast2
uniprot id: Q14TH2
names: Caution
names: Cofactor
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

31033:LOC101067618
gene id: 31033:LOC101067618
uniprot id: Q1L0L3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Membrane

31033:dgat1
gene id: 31033:dgat1
uniprot id: H2U4I6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the membrane-bound acyltransferase family. Sterol o-acyltransferase subfamily.
messages: Endoplasmic reticulum membrane
messages: Homodimer or homotetramer; both forms have similar enzymatic activities.
messages: Membrane

31033:LOC101080230
gene id: 31033:LOC101080230
uniprot id: A0A3B5KIW1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

31033:fdft1
gene id: 31033:fdft1
uniprot id: H2U1X3
names: Function
names: Similarity
messages: Belongs to the phytoene/squalene synthase family.
messages: Catalyzes the condensation of 2 farnesyl pyrophosphate (FPP) moieties to form squalene.

31033:coq5
gene id: 31033:coq5
uniprot id: H2UWF2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Component of a multi-subunit COQ enzyme complex, composed of at least COQ3, COQ4, COQ5, COQ6, COQ7 and COQ9.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).
messages: Mitochondrion inner membrane

31033:dkk2
gene id: 31033:dkk2
uniprot id: A0A3B5K2Y3
names: Similarity
messages: Belongs to the dickkopf family.

31033:st7
gene id: 31033:st7
uniprot id: Q8UW40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ST7 family.
messages: Membrane

31033:gp91phox
gene id: 31033:gp91phox
uniprot id: Q7T1Q1
names: Subcellular Location Annotation
messages: Membrane

31033:LOC101073797
gene id: 31033:LOC101073797
uniprot id: H2U7H3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LAMP family.
messages: Endosome membrane

31033:med22
gene id: 31033:med22
uniprot id: A0A674NQ09
names: Function
names: Subcellular Location Annotation
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Nucleus

31033:ywhaz
gene id: 31033:ywhaz
uniprot id: H2TYG6
names: Similarity
names: Subunit
messages: Belongs to the 14-3-3 family.
messages: Homodimer, and heterodimer with other family members.

31033:vldlr
gene id: 31033:vldlr
uniprot id: H2SFQ8
uniprot id: H2SFR2
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: clathrin-coated pit

31033:naa60
gene id: 31033:naa60
uniprot id: A0A3B5KEJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetyltransferase family. NAA60 subfamily.
messages: Golgi apparatus membrane

31033:LOC101078198
gene id: 31033:LOC101078198
uniprot id: H2T2S3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELO family. ELOVL1 subfamily.
messages: Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that exhibits activity toward saturated C18 to C26 acyl-CoA substrates, with the highest activity towards C22:0 acyl-CoA. May participate to the production of both saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: The C-terminal di-lysine motif may confer endoplasmic reticulum localization.

31033:naa35
gene id: 31033:naa35
uniprot id: H2TAI2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MAK10 family.
messages: Component of the N-terminal acetyltransferase C (NatC) complex, which is composed of NAA35, NAA38 and NAA30.
messages: Cytoplasm

31033:LOC101063230
gene id: 31033:LOC101063230
uniprot id: A0A3B5KKN5
names: Similarity
messages: Belongs to the SH3BGR family.

31033:tmbim6
gene id: 31033:tmbim6
uniprot id: H2RLE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

31033:fzd8
gene id: 31033:fzd8
uniprot id: A0A3B5JW14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor Fz/Smo family.
messages: Membrane

31033:trmt6
gene id: 31033:trmt6
uniprot id: A0A674PDM5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRM6/GCD10 family.
messages: Heterotetramer.
messages: Nucleus
messages: Substrate-binding subunit of tRNA (adenine-N1-)-methyltransferase, which catalyzes the formation of N1-methyladenine at position 58 (m1A58) in initiator methionyl-tRNA.

31033:gjd2
gene id: 31033:gjd2
uniprot id: H2UIE6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

31033:cdk2ap1
gene id: 31033:cdk2ap1
uniprot id: A0A3B5KMQ5
names: Similarity
messages: Belongs to the CDK2AP family.

31033:atp1b3
gene id: 31033:atp1b3
uniprot id: A0A674PJH6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the X(+)/potassium ATPases subunit beta family.
messages: Membrane
messages: This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane.

31033:fmnl3
gene id: 31033:fmnl3
uniprot id: A0A674P3B3
uniprot id: A0A674PBJ9
uniprot id: H2TDE1
names: Similarity
messages: Belongs to the formin homology family.

31033:sord
gene id: 31033:sord
uniprot id: A0A674NDX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the zinc-containing alcohol dehydrogenase family.
messages: Mitochondrion membrane
messages: flagellum

31033:LOC101073672
gene id: 31033:LOC101073672
uniprot id: A0A3B5KLY3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ENY2 family.
messages: Component of the nuclear pore complex (NPC)-associated TREX-2 complex (transcription and export complex 2). Component of the SAGA transcription coactivator-HAT complex. Within the SAGA complex, participates to a subcomplex of SAGA called the DUB module (deubiquitination module).
messages: Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. The transcription regulatory histone acetylation (HAT) complex SAGA is a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex that specifically deubiquitinates histones. The SAGA complex is recruited to specific gene promoters by activators, where it is required for transcription. The TREX-2 complex functions in docking export-competent ribonucleoprotein particles (mRNPs) to the nuclear entrance of the nuclear pore complex (nuclear basket). TREX-2 participates in mRNA export and accurate chromatin positioning in the nucleus by tethering genes to the nuclear periphery.
messages: nucleoplasm

31033:LOC101064433
gene id: 31033:LOC101064433
uniprot id: H2UYX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
messages: Cleavage furrow
messages: Midbody
messages: cilium membrane
messages: spindle

31033:dll4
gene id: 31033:dll4
uniprot id: H2U7H0
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Putative Notch ligand involved in the mediation of Notch signaling.

31033:nus1
gene id: 31033:nus1
uniprot id: A0A674MGN0
names: Similarity
messages: Belongs to the UPP synthase family.

31033:tp53i11
gene id: 31033:tp53i11
uniprot id: A0A674P338
names: Subcellular Location Annotation
messages: Membrane

31033:arhgap26
gene id: 31033:arhgap26
uniprot id: H2SU86
names: Subcellular Location Annotation
messages: cytoskeleton
messages: focal adhesion

31033:LOC101073275
gene id: 31033:LOC101073275
uniprot id: A0A3B5K0W8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

31033:vdac1
gene id: 31033:vdac1
uniprot id: A0A674PD97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic mitochondrial porin family.
messages: Cell membrane
messages: Membrane
messages: Membrane raft

31033:dhrsx
gene id: 31033:dhrsx
uniprot id: A0A674NC98
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

31033:hoxb2
gene id: 31033:hoxb2
uniprot id: Q6IEI0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family. Proboscipedia subfamily.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

31033:LOC101079883
gene id: 31033:LOC101079883
uniprot id: A0A674NB97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxin-13 family.
messages: Membrane
messages: Peroxisome membrane

31033:hbegf
gene id: 31033:hbegf
uniprot id: A0A3B5K1I4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

31033:cenpx
gene id: 31033:cenpx
uniprot id: A0A3B5K538
names: Similarity
messages: Belongs to the CENP-X/MHF2 family.

31033:itprip
gene id: 31033:itprip
uniprot id: Q90XY5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ITPRIP family.
messages: Cell membrane
messages: Enhances Ca(2+)-mediated inhibition of inositol 1,4,5-triphosphate receptor (ITPR) Ca(2+) release.
messages: Nucleus outer membrane

31033:LOC101074292
gene id: 31033:LOC101074292
uniprot id: A0A3B5JWJ3
names: Function
messages: Promotes degradation of target mRNA species. Plays a role in the regulation of circadian mRNA stability. Binds GTP and has GTPase activity.

31033:LOC101078451
gene id: 31033:LOC101078451
uniprot id: O42504
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

31033:eif2s2
gene id: 31033:eif2s2
uniprot id: A0A3B5K6A8
names: Similarity
messages: Belongs to the eIF-2-beta/eIF-5 family.

31033:LOC101079283
gene id: 31033:LOC101079283
uniprot id: H2VDZ3
names: Domain
names: Function
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: Converts 1-acyl-sn-glycerol-3-phosphate (lysophosphatidic acid or LPA) into 1,2-diacyl-sn-glycerol-3-phosphate (phosphatidic acid or PA) by incorporating an acyl moiety at the sn-2 position of the glycerol backbone.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

31033:LOC101063572
gene id: 31033:LOC101063572
uniprot id: H2SN66
names: Subcellular Location Annotation
messages: Membrane

31033:LOC101063191
gene id: 31033:LOC101063191
uniprot id: H2UL58
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

31033:LOC101067106
gene id: 31033:LOC101067106
uniprot id: A0A674NA58
names: Subcellular Location Annotation
messages: Membrane

31033:LOC101065113
gene id: 31033:LOC101065113
uniprot id: A0A3B5KH02
names: Subcellular Location Annotation
messages: Nucleus

31033:LOC101070032
gene id: 31033:LOC101070032
uniprot id: A0A674NYF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tropomyosin family.
messages: cytoskeleton

31033:adprhl1
gene id: 31033:adprhl1
uniprot id: H2V4H9
names: Similarity
messages: Belongs to the ADP-ribosylglycohydrolase family.

31033:LOC101071626
gene id: 31033:LOC101071626
uniprot id: H2RSZ8
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

31033:LOC446095
gene id: 31033:LOC446095
uniprot id: Q6IVY6
names: Similarity
messages: Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.

31033:il-21
gene id: 31033:il-21
uniprot id: Q599U2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-15/IL-21 family.
messages: Secreted

31033:nell1
gene id: 31033:nell1
uniprot id: A0A674N9V0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

31033:LOC101068223
gene id: 31033:LOC101068223
uniprot id: A0A3B5KMT1
names: Similarity
messages: Belongs to the COX20 family.

31033:gprc5b
gene id: 31033:gprc5b
uniprot id: A0A674NYC2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

31033:nans
gene id: 31033:nans
uniprot id: H2US31
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type-III AFP family.
messages: Contributes to protect fish blood from freezing at subzero sea water temperatures. Lowers the blood freezing point. Binds to nascent ice crystals and prevents further growth.
messages: Secreted

31033:efna1
gene id: 31033:efna1
uniprot id: A0A3B5K8B1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ephrin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

31033:LOC101073138
gene id: 31033:LOC101073138
uniprot id: H2ST59
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

31033:LOC101076878
gene id: 31033:LOC101076878
uniprot id: H2TVR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Belongs to the chemokine-like receptor (CMKLR) family.
messages: Cell membrane
messages: Membrane

31033:LOC101079075
gene id: 31033:LOC101079075
uniprot id: A0A674NZR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

31033:LOC101062122
gene id: 31033:LOC101062122
uniprot id: A0A3B5K2X3
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

31033:bet1
gene id: 31033:bet1
uniprot id: H2UR03
names: Subcellular Location Annotation
messages: Membrane

31033:lhx1
gene id: 31033:lhx1
uniprot id: H2RJP6
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

31033:LOC101065902
gene id: 31033:LOC101065902
uniprot id: A0A674PN87
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the organo anion transporter (TC 2.A.60) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

31033:ppil2
gene id: 31033:ppil2
uniprot id: H2UPH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cyclophilin-type PPIase family. PPIL2 subfamily.
messages: Nucleus

31033:ncam1
gene id: 31033:ncam1
uniprot id: A0A674MQD5
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: This protein is a cell adhesion molecule involved in neuron-neuron adhesion, neurite fasciculation, outgrowth of neurites, etc.

31033:eno1
gene id: 31033:eno1
uniprot id: H2TDQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Cytoplasm

31033:LOC101066709
gene id: 31033:LOC101066709
uniprot id: H2RNT0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endosulfine family.
messages: Cytoplasm
messages: Protein phosphatase inhibitor that specifically inhibits protein phosphatase 2A (PP2A) during mitosis.

31033:eda
gene id: 31033:eda
uniprot id: A0A3B5JZP9
names: Similarity
messages: Belongs to the tumor necrosis factor family.

31033:cactin
gene id: 31033:cactin
uniprot id: H2SVY1
names: Similarity
messages: Belongs to the CACTIN family.

31033:rab3gap1
gene id: 31033:rab3gap1
uniprot id: H2SMU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Rab3-GAP catalytic subunit family.
messages: Cytoplasm

31033:nampt
gene id: 31033:nampt
uniprot id: A0A674NXI2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NAPRTase family.
messages: Cytoplasm
messages: Homodimer.
messages: Nucleus
messages: Secreted

31033:LOC497187
gene id: 31033:LOC497187
uniprot id: H2U1E3
names: Similarity
messages: Belongs to the intermediate filament family.

31033:mfsd14a
gene id: 31033:mfsd14a
uniprot id: A0A674MDD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily.
messages: Membrane

31033:LOC101076991
gene id: 31033:LOC101076991
uniprot id: H2RMA0
names: Subcellular Location Annotation
messages: nucleoplasm

31033:slc25a3
gene id: 31033:slc25a3
uniprot id: H2TRS0
uniprot id: H2TRS1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Interacts with PPIF; the interaction is impaired by CsA.
messages: Membrane
messages: Mitochondrion inner membrane

31033:LOC101065496
gene id: 31033:LOC101065496
uniprot id: A0A674NFI3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

31033:usp39
gene id: 31033:usp39
uniprot id: H2TV64
names: Subcellular Location Annotation
messages: Nucleus

31033:LOC101072995
gene id: 31033:LOC101072995
uniprot id: A0A674P7D2
names: Similarity
messages: Belongs to the TENT family.

31033:cdc25b
gene id: 31033:cdc25b
uniprot id: H2V785
names: Function
names: Similarity
messages: Belongs to the MPI phosphatase family.
messages: Functions as a dosage-dependent inducer in mitotic control. Tyrosine protein phosphatase required for progression of the cell cycle.

31033:srd5a1
gene id: 31033:srd5a1
uniprot id: H2U0S4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the steroid 5-alpha reductase family.
messages: Converts testosterone into 5-alpha-dihydrotestosterone and progesterone or corticosterone into their corresponding 5-alpha-3-oxosteroids. It plays a central role in sexual differentiation and androgen physiology.
messages: Membrane
messages: Microsome membrane

31033:tmcc3
gene id: 31033:tmcc3
uniprot id: H2UNY3
names: Similarity
messages: Belongs to the TEX28 family.

31033:LOC101076124
gene id: 31033:LOC101076124
uniprot id: H2V277
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CELF/BRUNOL family.
messages: Cytoplasm

31033:slc39a3
gene id: 31033:slc39a3
uniprot id: Q6QQT0
names: Subcellular Location Annotation
messages: Membrane

31033:agtr1
gene id: 31033:agtr1
uniprot id: H2V8H5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for angiotensin II, a vasoconstricting peptide, which acts as a key regulator of blood pressure and sodium retention by the kidney. The activated receptor in turn couples to G-alpha proteins G(q) and thus activates phospholipase C and increases the cytosolic Ca(2+) concentrations, which in turn triggers cellular responses such as stimulation of protein kinase C.

31033:mief1
gene id: 31033:mief1
uniprot id: A0A3B5K9H0
names: Subcellular Location Annotation
messages: Membrane
messages: Mitochondrion outer membrane

31033:pga
gene id: 31033:pga
uniprot id: Q5TLU9
names: Similarity
messages: Belongs to the peptidase A1 family.

31033:mrs2
gene id: 31033:mrs2
uniprot id: H2TZ84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mitochondrion inner membrane

31033:LOC101078740
gene id: 31033:LOC101078740
uniprot id: H2V4E5
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

31033:becn1
gene id: 31033:becn1
uniprot id: Q4A1K9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beclin family.
messages: Cytoplasm
messages: Endoplasmic reticulum membrane
messages: Endosome membrane
messages: Membrane
messages: Mitochondrion membrane
messages: Plays a central role in autophagy.
messages: autophagosome
messages: trans-Golgi network membrane

31033:shroom2
gene id: 31033:shroom2
uniprot id: H2U2W2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the shroom family.
messages: cytoskeleton

31033:slc35e3
gene id: 31033:slc35e3
uniprot id: H2T358
names: Subcellular Location Annotation
messages: Membrane

31033:LOC101077641
gene id: 31033:LOC101077641
uniprot id: H2UGJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SOSS-C family.
messages: Component of the SOSS complex, a multiprotein complex that functions downstream of the MRN complex to promote DNA repair and G2/M checkpoint. The SOSS complex associates with single-stranded DNA at DNA lesions and influences diverse endpoints in the cellular DNA damage response including cell-cycle checkpoint activation, recombinational repair and maintenance of genomic stability. Required for efficient homologous recombination-dependent repair of double-strand breaks (DSBs).
messages: Component of the SOSS complex.
messages: Nucleus

31033:LOC101072236
gene id: 31033:LOC101072236
uniprot id: H2UK16
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes medium subunit family.
messages: Cytoplasmic vesicle membrane
messages: Golgi apparatus
messages: Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes.

31033:atad2b
gene id: 31033:atad2b
uniprot id: H2SMJ1
names: Similarity
messages: Belongs to the AAA ATPase family.

31033:dvl2
gene id: 31033:dvl2
uniprot id: H2UCB6
names: Similarity
messages: Belongs to the DSH family.

31033:cldn3d
gene id: 31033:cldn3d
uniprot id: Q6E5R9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

31033:LOC101072576
gene id: 31033:LOC101072576
uniprot id: H2TUP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. ADGF subfamily.
messages: Secreted

31033:ndor1
gene id: 31033:ndor1
uniprot id: H2T0C4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NADPH-dependent diflavin oxidoreductase NDOR1 family.
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: In the N-terminal section; belongs to the flavodoxin family.
messages: Interacts with CIAPIN1; as part of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NADPH-dependent reductase which is a central component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery. Transfers electrons from NADPH via its FAD and FMN prosthetic groups to the [2Fe-2S] cluster of CIAPIN1, another key component of the CIA machinery. In turn, this reduced cluster provides electrons for assembly of cytosolic iron-sulfur cluster proteins. It can also reduce the [2Fe-2S] cluster of CISD1 and activate this protein implicated in Fe/S cluster repair.
messages: perinuclear region

31033:polr2h
gene id: 31033:polr2h
uniprot id: H2T2K8
names: Function
names: Similarity
messages: Belongs to the eukaryotic RPB8 RNA polymerase subunit family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non-coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively.

31033:kri1
gene id: 31033:kri1
uniprot id: A0A674NWF7
names: Similarity
messages: Belongs to the KRI1 family.

31033:LOC101063371
gene id: 31033:LOC101063371
uniprot id: H2UMP9
names: Similarity
messages: Belongs to the ependymin family.

31033:krt222
gene id: 31033:krt222
uniprot id: H2SXM1
names: Similarity
messages: Belongs to the intermediate filament family.

31033:LOC101076680
gene id: 31033:LOC101076680
uniprot id: A0A674MV74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

31033:LOC101064422
gene id: 31033:LOC101064422
uniprot id: H2U7J4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

31033:urad
gene id: 31033:urad
uniprot id: H2SNG7
names: Function
names: Similarity
messages: Belongs to the OHCU decarboxylase family.
messages: Catalyzes the stereoselective decarboxylation of 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU) to (S)-allantoin.

31033:ormdl2
gene id: 31033:ormdl2
uniprot id: A0A3B5KAT4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ORM family.
messages: Membrane
messages: Negative regulator of sphingolipid synthesis.

31033:urm1
gene id: 31033:urm1
uniprot id: H2T9P0
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a sulfur carrier required for 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Serves as sulfur donor in tRNA 2-thiolation reaction by being thiocarboxylated (-COSH) at its C-terminus by MOCS3. The sulfur is then transferred to tRNA to form 2-thiolation of mcm(5)S(2)U. Also acts as a ubiquitin-like protein (UBL) that is covalently conjugated via an isopeptide bond to lysine residues of target proteins. The thiocarboxylated form serves as substrate for conjugation and oxidative stress specifically induces the formation of UBL-protein conjugates.
messages: Belongs to the URM1 family.
messages: C-terminal thiocarboxylation occurs in 2 steps, it is first acyl-adenylated (-COAMP) via the hesA/moeB/thiF part of MOCS3, then thiocarboxylated (-COSH) via the rhodanese domain of MOCS3.
messages: Cytoplasm

31033:LOC101074868
gene id: 31033:LOC101074868
uniprot id: A0A3B5KD16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dwarfin/SMAD family.
messages: Cytoplasm
messages: Nucleus

31033:LOC101078123
gene id: 31033:LOC101078123
uniprot id: H2SR25
names: Subcellular Location Annotation
messages: Membrane

31033:LOC101074676
gene id: 31033:LOC101074676
uniprot id: H2S2D3
names: Subcellular Location Annotation
messages: Nucleus

31033:prdm10
gene id: 31033:prdm10
uniprot id: H2TWQ1
names: Function
names: Subcellular Location Annotation
messages: May be involved in transcriptional regulation.
messages: Nucleus

31033:LOC101070087
gene id: 31033:LOC101070087
uniprot id: A0A3B5JUJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SFT2 family.
messages: May be involved in fusion of retrograde transport vesicles derived from an endocytic compartment with the Golgi complex.
messages: Membrane

31033:LOC101079925
gene id: 31033:LOC101079925
uniprot id: A0A674NWU1
names: Similarity
messages: Belongs to the GTP cyclohydrolase I family.

31033:psme3
gene id: 31033:psme3
uniprot id: A0A674NT88
names: Similarity
messages: Belongs to the PA28 family.

31033:LOC101064780
gene id: 31033:LOC101064780
uniprot id: A0A3B5KFQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAF1 family.
messages: Nucleus

31033:LOC101063891
gene id: 31033:LOC101063891
uniprot id: A0A674NMC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heparin-binding growth factors family.
messages: Cytoplasm
messages: dendrite
messages: filopodium
messages: growth cone
messages: sarcolemma

31033:srrt
gene id: 31033:srrt
uniprot id: H2UVX4
names: Similarity
messages: Belongs to the ARS2 family.

31033:fghce
gene id: 31033:fghce
uniprot id: Q2PED7
names: Caution
names: Cofactor
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

31033:LOC101080234
gene id: 31033:LOC101080234
uniprot id: A0A674NY87
names: Similarity
messages: Belongs to the DDA1 family.

31033:tfip11
gene id: 31033:tfip11
uniprot id: A1XDA3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFP11/STIP family.
messages: Involved in pre-mRNA splicing, specifically in spliceosome disassembly during late-stage splicing events.
messages: Nucleus

31033:LOC101068270
gene id: 31033:LOC101068270
uniprot id: Q8AV21
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

31033:LOC101078322
gene id: 31033:LOC101078322
uniprot id: A0A674P8F5
names: Similarity
messages: Belongs to the peptidase S8 family.

31033:apoc2
gene id: 31033:apoc2
uniprot id: Q5KSU0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the apolipoprotein C2 family.
messages: Component of chylomicrons, very low-density lipoproteins (VLDL), low-density lipoproteins (LDL), and high-density lipoproteins (HDL) in plasma. Plays an important role in lipoprotein metabolism as an activator of lipoprotein lipase.
messages: Secreted

31033:LOC101073247
gene id: 31033:LOC101073247
uniprot id: H2UPV0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family.
messages: Cytoplasmic granule membrane
messages: Membrane
messages: Monomer. Homodimer; disulfide-linked.
messages: Secreted
messages: The N- and C-terminal barrels adopt an identical fold despite having only 13% of conserved residues.
messages: The N-terminal region may be exposed to the interior of the granule, whereas the C-terminal portion may be embedded in the membrane. During phagocytosis and degranulation, proteases may be released and activated and cleave BPI at the junction of the N- and C-terminal portions of the molecule, providing controlled release of the N-terminal antibacterial fragment when bacteria are ingested.
messages: The cytotoxic action of BPI is limited to many species of Gram-negative bacteria; this specificity may be explained by a strong affinity of the very basic N-terminal half for the negatively charged lipopolysaccharides that are unique to the Gram-negative bacterial outer envelope.

31033:LOC101066261
gene id: 31033:LOC101066261
uniprot id: H2RM84
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the peptidase C1 family.
messages: Cell membrane
messages: Secreted

31033:LOC101067170
gene id: 31033:LOC101067170
uniprot id: H2SGJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HMGB family.
messages: Chromosome

31033:sptlc2
gene id: 31033:sptlc2
uniprot id: A0A674NTM7
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

31033:LOC101077902
gene id: 31033:LOC101077902
uniprot id: H2USD8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxisomal membrane protein PXMP2/4 family.
messages: Membrane

31033:sufu
gene id: 31033:sufu
uniprot id: H2TXY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUFU family.
messages: Cytoplasm
messages: Nucleus

31033:LOC101063004
gene id: 31033:LOC101063004
uniprot id: H2UAX9
names: Subcellular Location Annotation
messages: Membrane

31033:LOC101065996
gene id: 31033:LOC101065996
uniprot id: H2U8M1
names: Similarity
messages: Belongs to the G-alpha family. G(s) subfamily.

31033:LOC101077527
gene id: 31033:LOC101077527
uniprot id: H2SQ30
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Major role in the synthesis of nucleoside triphosphates other than ATP.
messages: Nucleus
messages: lamellipodium
messages: ruffle

31033:dxo
gene id: 31033:dxo
uniprot id: A0A3B5KK98
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DXO/Dom3Z family.
messages: Binds 2 magnesium ions.
messages: Decapping enzyme for NAD-capped RNAs: specifically hydrolyzes the nicotinamide adenine dinucleotide (NAD) cap from a subset of RNAs by removing the entire NAD moiety from the 5'-end of an NAD-capped RNA.
messages: Nucleus

31033:upf2
gene id: 31033:upf2
uniprot id: H2T1T5
names: Subcellular Location Annotation
messages: Cytoplasm

31033:LOC101068797
gene id: 31033:LOC101068797
uniprot id: A0A674MRV7
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

31033:tmem14a
gene id: 31033:tmem14a
uniprot id: A0A674PCQ2
names: Similarity
messages: Belongs to the TMEM14 family.

31033:rpl3
gene id: 31033:rpl3
uniprot id: A0A3B5KH25
names: Similarity
messages: Belongs to the universal ribosomal protein uL3 family.

31033:gclm
gene id: 31033:gclm
uniprot id: H2RNS3
names: Similarity
names: Subunit
messages: Belongs to the aldo/keto reductase family. Glutamate--cysteine ligase light chain subfamily.
messages: Heterodimer of a catalytic heavy chain and a regulatory light chain.

31033:rapsn
gene id: 31033:rapsn
uniprot id: H2UQA8
names: Similarity
messages: Belongs to the RAPsyn family.

31033:LOC101066156
gene id: 31033:LOC101066156
uniprot id: A0A3B5KIY9
names: Function
names: Similarity
messages: Belongs to the KCMF1 family.
messages: Has intrinsic E3 ubiquitin ligase activity and promotes ubiquitination.

31033:phf8
gene id: 31033:phf8
uniprot id: A0A674PKK8
names: Similarity
messages: Belongs to the JHDM1 histone demethylase family. JHDM1D subfamily.

31033:kin
gene id: 31033:kin
uniprot id: A0A674MZF0
names: Similarity
messages: Belongs to the KIN17 family.

31033:LOC101064546
gene id: 31033:LOC101064546
uniprot id: H2TLJ3
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

31033:LOC101061248
gene id: 31033:LOC101061248
uniprot id: H2UWB5
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

31033:ehd2
gene id: 31033:ehd2
uniprot id: H2TLF0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Endosome membrane
messages: Membrane

31033:bmpr2
gene id: 31033:bmpr2
uniprot id: A0A674MIS1
names: Similarity
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.

31033:jam2
gene id: 31033:jam2
uniprot id: A0A674MW02
uniprot id: H2TN49
names: Subcellular Location Annotation
messages: Membrane

31033:lgr6
gene id: 31033:lgr6
uniprot id: H2TVE7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

31033:grb14
gene id: 31033:grb14
uniprot id: H2RPN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GRB7/10/14 family.
messages: Cytoplasm

31033:sparc
gene id: 31033:sparc
uniprot id: Q6PVV7
names: Similarity
messages: Belongs to the SPARC family.

31033:LOC101065417
gene id: 31033:LOC101065417
uniprot id: A0A674NUH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

31033:nr2f6
gene id: 31033:nr2f6
uniprot id: H2SD73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

31033:polr2g
gene id: 31033:polr2g
uniprot id: A0A3B5K0Y3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic RPB7/RPC8 RNA polymerase subunit family.
messages: Component of the RNA polymerase II (Pol II) complex consisting of 12 subunits. RPB4 and RPB7 form a subcomplex that protrudes from the 10-subunit Pol II core complex.
messages: Nucleus

31033:LOC101062896
gene id: 31033:LOC101062896
uniprot id: H2U5I5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane

31033:mmd
gene id: 31033:mmd
uniprot id: A0A3B5KIC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

31033:LOC101074712
gene id: 31033:LOC101074712
uniprot id: H2UGM6
names: Subcellular Location Annotation
messages: Early endosome membrane
messages: Endosome membrane

31033:naa40
gene id: 31033:naa40
uniprot id: A0A674PGM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetyltransferase family. NAA40 subfamily.
messages: Cytoplasm
messages: Nucleus

31033:aipl1
gene id: 31033:aipl1
uniprot id: H2UWL4
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: May be important in protein trafficking and/or protein folding and stabilization.
messages: Nucleus

31033:atp5f1e
gene id: 31033:atp5f1e
uniprot id: A0A674P2M6
names: Function
names: Similarity
messages: Belongs to the eukaryotic ATPase epsilon family.
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(1) domain and of the central stalk which is part of the complex rotary element. Rotation of the central stalk against the surrounding alpha(3)beta(3) subunits leads to hydrolysis of ATP in three separate catalytic sites on the beta subunits.

31033:lef1
gene id: 31033:lef1
uniprot id: H2TAM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCF/LEF family.
messages: Nucleus

31033:fabp7
gene id: 31033:fabp7
uniprot id: H2TV98
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

31033:LOC101067313
gene id: 31033:LOC101067313
uniprot id: A0A674N951
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
messages: Cytoplasm

31033:LOC101065989
gene id: 31033:LOC101065989
uniprot id: H2U038
names: Similarity
messages: Belongs to the CRK family.

31033:akt1
gene id: 31033:akt1
uniprot id: H2UBQ0
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. RAC subfamily.

31033:gpat4
gene id: 31033:gpat4
uniprot id: H2SA56
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

31033:tbx22
gene id: 31033:tbx22
uniprot id: H2TRG0
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

31033:vps53
gene id: 31033:vps53
uniprot id: A0A3B5K7J9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS53 family.
messages: Endosome membrane
messages: Membrane
messages: trans-Golgi network membrane

31033:LOC101070521
gene id: 31033:LOC101070521
uniprot id: H2SWR8
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MNB/DYRK subfamily.

31033:LOC101077341
gene id: 31033:LOC101077341
uniprot id: A0A3B5KEP2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ephrin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

31033:map2k2
gene id: 31033:map2k2
uniprot id: A0A674N3S8
names: Similarity
messages: Belongs to the protein kinase superfamily.

31033:dnal4
gene id: 31033:dnal4
uniprot id: A0A674MPH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dynein light chain family.
messages: cytoskeleton

31033:LOC101063387
gene id: 31033:LOC101063387
uniprot id: A0A3B5KBM2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

31033:mc1r
gene id: 31033:mc1r
uniprot id: Q7ZSY9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase.

31033:oprl1
gene id: 31033:oprl1
uniprot id: A0A674MMX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

31033:LOC101070560
gene id: 31033:LOC101070560
uniprot id: H2RPW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

31033:rnf13
gene id: 31033:rnf13
uniprot id: H2V608
names: Subcellular Location Annotation
messages: Membrane

31033:angptl4
gene id: 31033:angptl4
uniprot id: H2TF00
names: Subcellular Location Annotation
messages: Secreted

31033:LOC101077524
gene id: 31033:LOC101077524
uniprot id: H2SHF1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TFIIE beta subunit family.
messages: Nucleus
messages: Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.
messages: Tetramer of two alpha and two beta chains.

31033:dusp6
gene id: 31033:dusp6
uniprot id: Q8UW48
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.

31033:pax5
gene id: 31033:pax5
uniprot id: Q3LFR5
names: Subcellular Location Annotation
messages: Nucleus

31033:LOC101071570
gene id: 31033:LOC101071570
uniprot id: A0A674NG36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NKAIN family.
messages: Cell membrane
messages: Membrane

31033:LOC101077035
gene id: 31033:LOC101077035
uniprot id: H2RS58
names: Caution
names: Cofactor
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

31033:taf5
gene id: 31033:taf5
uniprot id: A0A674NZA1
names: Similarity
messages: Belongs to the WD repeat TAF5 family.

31033:LOC101079870
gene id: 31033:LOC101079870
uniprot id: H2RN11
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: GTP-binding protein involved in protein trafficking; modulates vesicle budding and uncoating within the Golgi apparatus.
messages: Golgi apparatus

31033:LOC101077481
gene id: 31033:LOC101077481
uniprot id: A0A674P807
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the myelin proteolipid protein family.
messages: Membrane

31033:LOC101068466
gene id: 31033:LOC101068466
uniprot id: A0A674PKJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dwarfin/SMAD family.
messages: Cytoplasm
messages: Nucleus

31033:LOC101071856
gene id: 31033:LOC101071856
uniprot id: A0A3B5K1M4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat L(2)GL family.
messages: Cell membrane
messages: Cytoplasm
messages: Membrane

31033:pygl
gene id: 31033:pygl
uniprot id: H2T3Z9
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.

31033:syndig1l
gene id: 31033:syndig1l
uniprot id: H2UQ20
names: Similarity
messages: Belongs to the CD225/Dispanin family.

31033:LOC101064331
gene id: 31033:LOC101064331
uniprot id: A0A674NJN2
names: Function
names: Similarity
messages: Belongs to the ferritin family.
messages: Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.

31033:cfap300
gene id: 31033:cfap300
uniprot id: A0A3B5K580
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CFAP300 family.
messages: Cilium- and flagellum-specific protein that plays a role in axonemal structure organization and motility. May play a role in outer and inner dynein arm assembly.
messages: Cytoplasm

31033:LOC101070322
gene id: 31033:LOC101070322
uniprot id: A0A674MZM2
names: Similarity
names: Subunit
messages: Belongs to the group II decarboxylase family.
messages: Homodimer.

31033:ppcs
gene id: 31033:ppcs
uniprot id: A0A3B5KL16
names: Similarity
messages: Belongs to the PPC synthetase family.

31033:get4
gene id: 31033:get4
uniprot id: A4GWN3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: As part of a cytosolic protein quality control complex, the bag6/bat3 complex, maintains misfolded and hydrophobic patches-containing proteins in a soluble state and participates in their proper delivery to the endoplasmic reticulum or alternatively can promote their sorting to the proteasome where they undergo degradation. The bag6/bat3 complex is involved in the post-translational delivery of tail-anchored/type II transmembrane proteins to the endoplasmic reticulum membrane. Similarly, the bag6/bat3 complex also functions as a sorting platform for proteins of the secretory pathway that are mislocalized to the cytosol either delivering them to the proteasome for degradation or to the endoplasmic reticulum. The bag6/bat3 complex also plays a role in the endoplasmic reticulum-associated degradation (ERAD), a quality control mechanism that eliminates unwanted proteins of the endoplasmic reticulum through their retrotranslocation to the cytosol and their targeting to the proteasome. It maintains these retrotranslocated proteins in an unfolded yet soluble state condition in the cytosol to ensure their proper delivery to the proteasome.
messages: Belongs to the GET4 family.
messages: Component of the bag6/bat3 complex.
messages: cytosol

31033:LOC101067191
gene id: 31033:LOC101067191
uniprot id: H2SUG3
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.

31033:pold1
gene id: 31033:pold1
uniprot id: H2SW10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-B family.
messages: Nucleus

31033:rbm48
gene id: 31033:rbm48
uniprot id: H2U2D5
names: Similarity
messages: Belongs to the RBM48 family.

31033:atg13
gene id: 31033:atg13
uniprot id: A0A674MZC9
uniprot id: H2SYP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATG13 family. Metazoan subfamily.
messages: Preautophagosomal structure

31033:LOC101068713
gene id: 31033:LOC101068713
uniprot id: H2SQY3
names: Similarity
messages: Belongs to the glycerophosphoryl diester phosphodiesterase family.

31033:slc5a8
gene id: 31033:slc5a8
uniprot id: H2SHT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

31033:LOC101066955
gene id: 31033:LOC101066955
uniprot id: A0A3B5K980
names: Similarity
messages: Belongs to the tumor necrosis factor family.

31033:me3
gene id: 31033:me3
uniprot id: H2U396
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

31033:eif2b2
gene id: 31033:eif2b2
uniprot id: Q90511
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eIF-2B alpha/beta/delta subunits family.
messages: Catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP.
messages: Complex of five different subunits; alpha, beta, gamma, delta and epsilon.

31033:b3gnt7
gene id: 31033:b3gnt7
uniprot id: A0A3B5KKS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

31033:ublcp1
gene id: 31033:ublcp1
uniprot id: A0A3B5KL27
names: Function
names: Subcellular Location Annotation
messages: Dephosphorylates 26S nuclear proteasomes, thereby decreasing their proteolytic activity. The dephosphorylation may prevent assembly of the core and regulatory particles (CP and RP) into mature 26S proteasome.
messages: Nucleus

31033:fah
gene id: 31033:fah
uniprot id: H2RNJ9
names: Similarity
messages: Belongs to the FAH family.

31033:LOC101061569
gene id: 31033:LOC101061569
uniprot id: H2T5X3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the organo anion transporter (TC 2.A.60) family.
messages: Cell membrane
messages: Membrane

31033:atp8a2
gene id: 31033:atp8a2
uniprot id: H2RUN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

31033:LOC101068470
gene id: 31033:LOC101068470
uniprot id: H2UT54
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.

31033:rsl24d1
gene id: 31033:rsl24d1
uniprot id: A0A3B5KIB9
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL24 family.

31033:LOC101074167
gene id: 31033:LOC101074167
uniprot id: H2RMQ8
names: Subcellular Location Annotation
messages: Nucleus

31033:zfp36l2
gene id: 31033:zfp36l2
uniprot id: A0A674PGX2
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Associates with the cytoplasmic CCR4-NOT deadenylase complex to trigger ARE-containing mRNA deadenylation and decay processes.
messages: Cytoplasm
messages: Nucleus
messages: Zinc-finger RNA-binding protein that destabilizes several cytoplasmic AU-rich element (ARE)-containing mRNA transcripts by promoting their poly(A) tail removal or deadenylation, and hence provide a mechanism for attenuating protein synthesis. Acts as a 3'-untranslated region (UTR) ARE mRNA-binding adapter protein to communicate signaling events to the mRNA decay machinery. Functions by recruiting the CCR4-NOT deadenylase complex and probably other components of the cytoplasmic RNA decay machinery to the bound ARE-containing mRNAs, and hence promotes ARE-mediated mRNA deadenylation and decay processes. Binds to 3'-UTR ARE of numerous mRNAs.

31033:phka1
gene id: 31033:phka1
uniprot id: H2SYZ9
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Although the final Cys may be farnesylated, the terminal tripeptide is probably not removed, and the C-terminus is not methylated.
messages: Belongs to the phosphorylase b kinase regulatory chain family.
messages: Cell membrane
messages: Membrane
messages: Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. The alpha chain may bind calmodulin.

31033:btg1
gene id: 31033:btg1
uniprot id: A0A674NQ03
names: Function
names: Similarity
messages: Anti-proliferative protein.
messages: Belongs to the BTG family.

31033:rxra
gene id: 31033:rxra
uniprot id: A0A674PLN8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nuclear hormone receptor family. NR2 subfamily.
messages: Composed of three domains: a modulating N-terminal domain, a DNA-binding domain and a C-terminal ligand-binding domain.
messages: Homodimer. Heterodimer; with a rar molecule.
messages: Nucleus
messages: Receptor for retinoic acid that acts as a transcription factor. Forms homo- or heterodimers with retinoic acid receptors (rars) and binds to target response elements in response to their ligands, all-trans or 9-cis retinoic acid, to regulate gene expression in various biological processes.

31033:stx16
gene id: 31033:stx16
uniprot id: A0A3B5K3L5
names: Similarity
messages: Belongs to the syntaxin family.

31033:LOC101067363
gene id: 31033:LOC101067363
uniprot id: H2SX67
names: Similarity
messages: Belongs to the SAPS family.

31033:tmem45a
gene id: 31033:tmem45a
uniprot id: H2TXW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM45 family.
messages: Membrane

31033:pnpt1
gene id: 31033:pnpt1
uniprot id: A0A3B5K500
names: Similarity
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.

31033:fut8
gene id: 31033:fut8
uniprot id: Q6EV74
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 23 family.
messages: Catalyzes the addition of fucose in alpha 1-6 linkage to the first GlcNAc residue, next to the peptide chains in N-glycans.
messages: Golgi stack membrane
messages: Membrane

31033:midn
gene id: 31033:midn
uniprot id: A0A3B5K4J6
names: Subcellular Location Annotation
messages: Nucleus

31033:cplx4
gene id: 31033:cplx4
uniprot id: A0A3B5K9R0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complexin/synaphin family.
messages: Synapse

31033:smoc2
gene id: 31033:smoc2
uniprot id: H2V823
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

31033:yrdc
gene id: 31033:yrdc
uniprot id: A0A674NZ18
names: Similarity
messages: Belongs to the SUA5 family.

31033:LOC101079551
gene id: 31033:LOC101079551
uniprot id: H2T1D4
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

31033:acy1
gene id: 31033:acy1
uniprot id: H2UHE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M20A family.
messages: Cytoplasm

31033:LOC101074476
gene id: 31033:LOC101074476
uniprot id: H2TWJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.
messages: dendrite

31033:cnnm4
gene id: 31033:cnnm4
uniprot id: H2UV60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ACDP family.
messages: Membrane

31033:LOC101062562
gene id: 31033:LOC101062562
uniprot id: Q5H716
names: Similarity
messages: Belongs to the Toll-like receptor family.

31033:enkd1
gene id: 31033:enkd1
uniprot id: H2UYC6
names: Subcellular Location Annotation
messages: cilium axoneme

31033:mrpl35
gene id: 31033:mrpl35
uniprot id: A0A674N792
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial ribosomal protein bL35 family.
messages: Mitochondrion

31033:LOC115246453
gene id: 31033:LOC115246453
uniprot id: H2V638
names: Function
names: Similarity
messages: Belongs to the profilin family.
messages: Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG.

31033:manbal
gene id: 31033:manbal
uniprot id: H2VCQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0239 family.
messages: Membrane

31033:kif19
gene id: 31033:kif19
uniprot id: H2VA28
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

31033:rag2
gene id: 31033:rag2
uniprot id: Q9W6A0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RAG2 family.
messages: Nucleus

31033:LOC101076296
gene id: 31033:LOC101076296
uniprot id: H2T2D0
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

31033:LOC101067992
gene id: 31033:LOC101067992
uniprot id: A0A674MTQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

31033:pfdn1
gene id: 31033:pfdn1
uniprot id: A0A674MF53
names: Similarity
messages: Belongs to the prefoldin subunit beta family.

31033:LOC101071352
gene id: 31033:LOC101071352
uniprot id: A0A3B5KN53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type I cytokine receptor family. Type 1 subfamily.
messages: Membrane

31033:LOC101074032
gene id: 31033:LOC101074032
uniprot id: H2TGT5
names: Subcellular Location Annotation
messages: Membrane

31033:pomt2
gene id: 31033:pomt2
uniprot id: A0A674MI13
uniprot id: H2UQD9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 39 family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins.

31033:LOC101079165
gene id: 31033:LOC101079165
uniprot id: H2UM08
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GnRH family.
messages: Secreted
messages: Stimulates the secretion of gonadotropins.

31033:gem
gene id: 31033:gem
uniprot id: H2TM01
names: Similarity
messages: Belongs to the small GTPase superfamily. RGK family.

31033:LOC101069580
gene id: 31033:LOC101069580
uniprot id: A0A3B5KF41
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

31033:LOC101068873
gene id: 31033:LOC101068873
uniprot id: H2RKA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptophysin/synaptobrevin family.
messages: Membrane

31033:golph3
gene id: 31033:golph3
uniprot id: A0A674PPZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GOLPH3/VPS74 family.
messages: Golgi stack membrane
messages: Membrane
messages: trans-Golgi network membrane

31033:mea1
gene id: 31033:mea1
uniprot id: H2S1U0
names: Function
messages: May play an important role in spermatogenesis and/or testis development.

31033:nlgn4a
gene id: 31033:nlgn4a
uniprot id: D2X2H1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type-B carboxylesterase/lipase family.
messages: Cell membrane
messages: Membrane

31033:LOC101070203
gene id: 31033:LOC101070203
uniprot id: A0A3B5K744
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM198 family.
messages: Membrane

31033:cdk2
gene id: 31033:cdk2
uniprot id: A0A674P2P3
names: Similarity
messages: Belongs to the protein kinase superfamily.

31033:xkr7
gene id: 31033:xkr7
uniprot id: Q5GH47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XK family.
messages: Membrane

31033:eif5
gene id: 31033:eif5
uniprot id: H2SUY2
names: Function
names: Similarity
messages: Belongs to the eIF-2-beta/eIF-5 family.
messages: Catalyzes the hydrolysis of GTP bound to the 40S ribosomal initiation complex (40S.mRNA.Met-tRNA[F].eIF-2.GTP) with the subsequent joining of a 60S ribosomal subunit resulting in the release of eIF-2 and the guanine nucleotide. The subsequent joining of a 60S ribosomal subunit results in the formation of a functional 80S initiation complex (80S.mRNA.Met-tRNA[F]).

31033:LOC101071295
gene id: 31033:LOC101071295
uniprot id: H2UJ73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane

31033:slc39a11
gene id: 31033:slc39a11
uniprot id: A0A3B5K362
names: Subcellular Location Annotation
messages: Membrane

31033:btbd10
gene id: 31033:btbd10
uniprot id: H2V6F6
names: Subcellular Location Annotation
messages: Cytoplasm

31033:dolk
gene id: 31033:dolk
uniprot id: A0A3B5KM43
names: Similarity
messages: Belongs to the polyprenol kinase family.

31033:jak1
gene id: 31033:jak1
uniprot id: A0A674NBS3
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. JAK subfamily.

31033:LOC101072167
gene id: 31033:LOC101072167
uniprot id: H2VEL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
messages: cytoskeleton

31033:pllp
gene id: 31033:pllp
uniprot id: H2T7G6
names: Subcellular Location Annotation
messages: Membrane

31033:LOC101069215
gene id: 31033:LOC101069215
uniprot id: I6L6Z9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

31033:LOC101072944
gene id: 31033:LOC101072944
uniprot id: A0A674NNM4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tweety family.
messages: Cell membrane
messages: Membrane
messages: Probable chloride channel.

31033:ndufa12
gene id: 31033:ndufa12
uniprot id: A0A3B5KAS8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA12 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

31033:LOC101069487
gene id: 31033:LOC101069487
uniprot id: H2T0I0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

31033:smim19
gene id: 31033:smim19
uniprot id: H2RQL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMIM19 family.
messages: Membrane

31033:LOC101079933
gene id: 31033:LOC101079933
uniprot id: H2SE18
names: Similarity
messages: Belongs to the complex I 23 kDa subunit family.

31033:ncaph
gene id: 31033:ncaph
uniprot id: H2TGH5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CND2 (condensin subunit 2) family.
messages: Chromosome
messages: Cytoplasm
messages: Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes.

31033:LOC101075770
gene id: 31033:LOC101075770
uniprot id: A0A6D2X4V5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for the neuromedin-U and neuromedin-S neuropeptides.

31033:mapkap1
gene id: 31033:mapkap1
uniprot id: H2RTX7
names: Similarity
messages: Belongs to the SIN1 family.

31033:stag1
gene id: 31033:stag1
uniprot id: H2UCF5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SCC3 family.
messages: Chromosome
messages: Component of cohesin complex, a complex required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate.
messages: Nucleus
messages: Part of the cohesin complex which is composed of a heterodimer between a SMC1 protein (SMC1A or SMC1B) and SMC3, which are attached via their hinge domain, and RAD21 which link them at their heads, and one STAG protein.
messages: centromere

31033:LOC446040
gene id: 31033:LOC446040
uniprot id: Q6SYV4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts specifically as a negative regulator of skeletal muscle growth.
messages: Belongs to the TGF-beta family.
messages: Homodimer; disulfide-linked.
messages: Secreted

31033:csnk2a2
gene id: 31033:csnk2a2
uniprot id: H2T3W7
names: Similarity
messages: Belongs to the protein kinase superfamily.

31033:vps4a
gene id: 31033:vps4a
uniprot id: H2S5W7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Membrane

31033:nfu1
gene id: 31033:nfu1
uniprot id: H2RSB5
names: Similarity
messages: Belongs to the NifU family.

31033:cert1
gene id: 31033:cert1
uniprot id: H2T1Y0
names: Subcellular Location Annotation
messages: Endoplasmic reticulum
messages: Golgi apparatus

31033:il-6
gene id: 31033:il-6
uniprot id: Q6L6X6
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
names: Tissue Specificity
messages: After induction, highly expressed in spleen. Can also be expressed in kidney after incubation with PHA.
messages: Belongs to the IL-6 superfamily.
messages: By LPS and PBS.
messages: Component of a hexamer of two molecules each of IL6, IL6R and IL6ST; first binds to IL6R to associate with the signaling subunit IL6ST.
messages: Cytokine with a wide variety of biological functions in immunity, tissue regeneration, and metabolism. Binds to IL6R, then the complex associates to the signaling subunit IL6ST/gp130 to trigger the intracellular IL6-signaling pathway. The interaction with the membrane-bound IL6R and IL6ST stimulates 'classic signaling', whereas the binding of IL6 and soluble IL6R to IL6ST stimulates 'trans-signaling'. Alternatively, 'cluster signaling' occurs when membrane-bound IL6:IL6R complexes on transmitter cells activate IL6ST receptors on neighboring receiver cells.
messages: Secreted

31033:LOC101078479
gene id: 31033:LOC101078479
uniprot id: H2UPN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Endoplasmic reticulum membrane
messages: Membrane

31033:calcr
gene id: 31033:calcr
uniprot id: A7Z0B8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 2 family.
messages: Cell membrane
messages: Interacts with GPRASP2.
messages: Membrane

31033:leprotl1
gene id: 31033:leprotl1
uniprot id: B3Y065
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OB-RGRP/VPS55 family.
messages: Membrane

31033:rab18
gene id: 31033:rab18
uniprot id: A0A674N6R6
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Cell membrane
messages: Lipid droplet

31033:ano7
gene id: 31033:ano7
uniprot id: H2SG05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anoctamin family.
messages: Membrane

31033:LOC101071462
gene id: 31033:LOC101071462
uniprot id: H2U8H0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transcription factor STAT family.
messages: Cytoplasm
messages: Nucleus

31033:gdpd2
gene id: 31033:gdpd2
uniprot id: H2TH64
names: Similarity
messages: Belongs to the glycerophosphoryl diester phosphodiesterase family.

31033:LOC101062993
gene id: 31033:LOC101062993
uniprot id: A0A3B5KMJ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Membrane
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. A homomeric c-ring of probably 10 subunits is part of the complex rotary element.
messages: Mitochondrion membrane

31033:msrb2
gene id: 31033:msrb2
uniprot id: H2RVH9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Binds 1 zinc ion per subunit.
messages: Methionine-sulfoxide reductase that specifically reduces methionine (R)-sulfoxide back to methionine. While in many cases methionine oxidation is the result of random oxidation following oxidative stress, methionine oxidation is also a post-translational modification that takes place on specific residues.

31033:brix1
gene id: 31033:brix1
uniprot id: H2TVU4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BRX1 family.
messages: Required for biogenesis of the 60S ribosomal subunit.
messages: nucleolus

31033:mrto4
gene id: 31033:mrto4
uniprot id: A0A674NAQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with the pre-60S ribosomal particle.
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes.
messages: Cytoplasm
messages: nucleolus

31033:mrpl4
gene id: 31033:mrpl4
uniprot id: H2T9P2
names: Similarity
messages: Belongs to the universal ribosomal protein uL4 family.

31033:stk17b
gene id: 31033:stk17b
uniprot id: A0A3B5K3N9
names: Similarity
messages: Belongs to the protein kinase superfamily.

31033:tlcd2
gene id: 31033:tlcd2
uniprot id: A0A3B5K592
names: Subcellular Location Annotation
messages: Membrane

31033:mok
gene id: 31033:mok
uniprot id: A0A674PA87
names: Similarity
messages: Belongs to the protein kinase superfamily.

31033:mgrn1
gene id: 31033:mgrn1
uniprot id: H2TY57
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: E3 ubiquitin ligase.

31033:elovl5
gene id: 31033:elovl5
uniprot id: H2UNL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELO family.
messages: Membrane

31033:tmem231
gene id: 31033:tmem231
uniprot id: A0A3B5KIZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM231 family.
messages: Membrane
messages: Transmembrane component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes. Required for ciliogenesis and sonic hedgehog/SHH signaling.
messages: cilium membrane

31033:tomm5
gene id: 31033:tomm5
uniprot id: A0A3B5K9E8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tom5 family.
messages: Membrane
messages: Mitochondrion outer membrane

31033:arid5b
gene id: 31033:arid5b
uniprot id: H2TQH7
names: Similarity
messages: Belongs to the ARID5B family.

31033:stat1
gene id: 31033:stat1
uniprot id: H2RJB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transcription factor STAT family.
messages: Cytoplasm
messages: Nucleus

31033:LOC101073369
gene id: 31033:LOC101073369
uniprot id: H2RUG3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Binds 2 magnesium ions per subunit. Is also active with manganese (in vitro).
messages: Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.
messages: Membrane

31033:atp5if1
gene id: 31033:atp5if1
uniprot id: H2TBT1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase inhibitor family.
messages: Endogenous F(1)F(o)-ATPase inhibitor limiting ATP depletion when the mitochondrial membrane potential falls below a threshold and the F(1)F(o)-ATP synthase starts hydrolyzing ATP to pump protons out of the mitochondrial matrix. Required to avoid the consumption of cellular ATP when the F(1)F(o)-ATP synthase enzyme acts as an ATP hydrolase.
messages: Forms an alpha-helical dimer with monomers associated via an antiparallel alpha-helical coiled coil, leaving each N-terminal inhibitory region accessible for interaction with an F1 catalytic domain. The inhibitory N-terminal region binds the alpha(ADP-bound)-beta(ADP-bound) (ATP5F1A-ATP5F1B) interface of F1-ATPase, and also contact the central gamma subunit (ATP5F1C). This dimeric state is favored by pH values below 7.0, and at higher values the dimers associate to form inactive homotetramer, where the inhibitory region is occluded, masking its inhibitory activity.
messages: Homodimer; represents the active form and is present at a pH value below 6.5. Homotetramer; represents the inactive form and is present at a pH value above 7.0.
messages: Indirectly acts as a regulator of heme synthesis in erythroid tissues: regulates heme synthesis by modulating the mitochondrial pH and redox potential, allowing fech to efficiently catalyze the incorporation of iron into protoporphyrin IX to produce heme.
messages: Mitochondrion

31033:LOC101068554
gene id: 31033:LOC101068554
uniprot id: H2RWI6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase M24 family. SPT16 subfamily.
messages: Chromosome
messages: Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of the nucleosome following the passage of RNA polymerase II.
messages: Component of the FACT complex.
messages: Nucleus

31033:LOC101077904
gene id: 31033:LOC101077904
uniprot id: A0A674NYM0
names: Subcellular Location Annotation
messages: Membrane

31033:LOC101070377
gene id: 31033:LOC101070377
uniprot id: Q6J5K2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
messages: Membrane
messages: Visual pigments are the light-absorbing molecules that mediate vision. They consist of an apoprotein, opsin, covalently linked to cis-retinal.

31033:LOC101072399
gene id: 31033:LOC101072399
uniprot id: H2RV36
names: Similarity
messages: Belongs to the carnitine/choline acetyltransferase family.

31033:LOC101078646
gene id: 31033:LOC101078646
uniprot id: H2SBL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calycin superfamily. Lipocalin family.
messages: Secreted

31033:pde6g
gene id: 31033:pde6g
uniprot id: A0A674PJW3
names: Function
names: Similarity
messages: Belongs to the rod/cone cGMP-PDE gamma subunit family.
messages: Participates in processes of transmission and amplification of the visual signal. cGMP-PDEs are the effector molecules in G-protein-mediated phototransduction in vertebrate rods and cones.

31033:LOC101070944
gene id: 31033:LOC101070944
uniprot id: A0A674PD63
names: Function
names: Similarity
messages: Belongs to the parvalbumin family.
messages: In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions.

31033:LOC101074060
gene id: 31033:LOC101074060
uniprot id: H2V488
names: Similarity
messages: Belongs to the cytochrome P450 family.

31033:hoxa10
gene id: 31033:hoxa10
uniprot id: Q1KKZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

31033:ccdc43
gene id: 31033:ccdc43
uniprot id: A0A3B5JZ64
names: Similarity
messages: Belongs to the CCDC43 family.

31033:oip5
gene id: 31033:oip5
uniprot id: A0A3B5KA07
names: Function
names: Subcellular Location Annotation
messages: Required for recruitment of CENPA to centromeres and normal chromosome segregation during mitosis.
messages: centromere

31033:ndufa5
gene id: 31033:ndufa5
uniprot id: H2TMC3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA5 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

31033:LOC101075987
gene id: 31033:LOC101075987
uniprot id: H2UFU9
names: Subcellular Location Annotation
messages: Nucleus

31033:scamp3
gene id: 31033:scamp3
uniprot id: H2TY00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCAMP family.
messages: Membrane

31033:trf3
gene id: 31033:trf3
uniprot id: Q6SJ94
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TBP family.
messages: Nucleus
messages: TATA box-binding transcription factor. Members of the TBP family are differentially required to regulate transcription and development during early embryogenesis (By similarity).

31033:LOC101076886
gene id: 31033:LOC101076886
uniprot id: A0A3B5KSL1
names: Subcellular Location Annotation
messages: Nucleus

31033:drd5
gene id: 31033:drd5
uniprot id: A0A3B5K8K4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

31033:LOC101077775
gene id: 31033:LOC101077775
uniprot id: H2SC36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

31033:tppp
gene id: 31033:tppp
uniprot id: A0A674MS92
names: Similarity
messages: Belongs to the TPPP family.

31033:c17h19orf53
gene id: 31033:c17h19orf53
uniprot id: A0A674NED8
names: Similarity
messages: Belongs to the UPF0390 family.

31033:avpr1a
gene id: 31033:avpr1a
uniprot id: Q5MZ02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.
messages: Cell membrane
messages: Membrane

31033:LOC101062925
gene id: 31033:LOC101062925
uniprot id: H2UJZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

31033:zdhhc24
gene id: 31033:zdhhc24
uniprot id: A0A3B5KGM7
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

31033:LOC101073860
gene id: 31033:LOC101073860
uniprot id: A0A674N2C7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit. The potassium ion interacts primarily with the substrate.
messages: Binds 2 magnesium ions per subunit. The magnesium ions interact primarily with the substrate.
messages: Catalyzes the formation of S-adenosylmethionine from methionine and ATP.

31033:slc5a3
gene id: 31033:slc5a3
uniprot id: H2TVI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

31033:LOC101077798
gene id: 31033:LOC101077798
uniprot id: A0A674PH28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

31033:LOC101069611
gene id: 31033:LOC101069611
uniprot id: Q1KL22
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

31033:LOC101077815
gene id: 31033:LOC101077815
uniprot id: A0A674PP22
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

31033:dmrta1
gene id: 31033:dmrta1
uniprot id: Q4AE29
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DMRT family.
messages: May be involved in sexual development.
messages: Nucleus

31033:LOC446087
gene id: 31033:LOC446087
uniprot id: A0A674PQS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

31033:LOC101072814
gene id: 31033:LOC101072814
uniprot id: A0A674PA35
names: Similarity
messages: Belongs to the protein kinase superfamily.

31033:selenbp1
gene id: 31033:selenbp1
uniprot id: H2T2U7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the selenium-binding protein family.
messages: Catalyzes the oxidation of methanethiol, an organosulfur compound known to be produced in substantial amounts by gut bacteria. Selenium-binding protein which may be involved in the sensing of reactive xenobiotics in the cytoplasm. May be involved in intra-Golgi protein transport.
messages: Membrane
messages: Nucleus
messages: cytosol

31033:LOC101079676
gene id: 31033:LOC101079676
uniprot id: A0A674NUF6
names: Function
names: Similarity
names: Subunit
messages: Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins.
messages: Belongs to the glycosyl hydrolase 29 family.
messages: Homotetramer.

31033:nrg2
gene id: 31033:nrg2
uniprot id: H2V2Z6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neuregulin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Secreted

31033:LOC101064659
gene id: 31033:LOC101064659
uniprot id: H2RJJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA2/NAM7 helicase family.
messages: Cytoplasm

31033:vkorc1
gene id: 31033:vkorc1
uniprot id: Q6TEK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VKOR family.
messages: Endoplasmic reticulum membrane
messages: Membrane

31033:LOC101064734
gene id: 31033:LOC101064734
uniprot id: H2T3T2
names: Similarity
messages: Belongs to the phosphatase 2A regulatory subunit B family.

31033:vamp7
gene id: 31033:vamp7
uniprot id: A0A3B5KHW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Membrane

31033:asah1
gene id: 31033:asah1
uniprot id: Q8JG45
names: Similarity
messages: Belongs to the acid ceramidase family.

31033:LOC101072989
gene id: 31033:LOC101072989
uniprot id: Q1KKX9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

31033:LOC101079064
gene id: 31033:LOC101079064
uniprot id: H2TAN6
names: Similarity
names: Subunit
messages: Belongs to the ENDOU family.
messages: Monomer.

31033:ppp2cb
gene id: 31033:ppp2cb
uniprot id: H2TU36
names: Similarity
messages: Belongs to the PPP phosphatase family.

31033:LOC101073356
gene id: 31033:LOC101073356
uniprot id: A0A3B5K6U0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BORCS7 family.
messages: Membrane

31033:LOC101077456
gene id: 31033:LOC101077456
uniprot id: H2SC53
names: Similarity
messages: Belongs to the multicopper oxidase family.

31033:eif3h
gene id: 31033:eif3h
uniprot id: H2T115
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit H family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
messages: Cytoplasm

31033:LOC101062906
gene id: 31033:LOC101062906
uniprot id: H2SQ95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the argonaute family.
messages: P-body

31033:katna1
gene id: 31033:katna1
uniprot id: H2SWN0
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATPase activity is stimulated by microtubules, which promote homooligomerization. ATP-dependent microtubule severing is stimulated by interaction with KATNB1.
messages: Belongs to the AAA ATPase family. Katanin p60 subunit A1 subfamily.
messages: Can homooligomerize into hexameric rings, which may be promoted by interaction with microtubules. Interacts with KATNB1, which may serve as a targeting subunit.
messages: Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation.
messages: Cytoplasm
messages: centrosome
messages: spindle
messages: spindle pole

31033:LOC101075850
gene id: 31033:LOC101075850
uniprot id: A0A674PJS1
names: Function
messages: Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds to G(i)-alpha and G(o)-alpha, but not to G(s)-alpha.

31033:wars2
gene id: 31033:wars2
uniprot id: H2UVY7
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

31033:sntg1
gene id: 31033:sntg1
uniprot id: A0A674ML37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the syntrophin family.
messages: cytoskeleton

31033:hm13
gene id: 31033:hm13
uniprot id: H2SSI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A22B family.
messages: Membrane

31033:fam20c1
gene id: 31033:fam20c1
uniprot id: I7LRF4
names: Similarity
messages: Belongs to the FAM20 family.

31033:ap2s1
gene id: 31033:ap2s1
uniprot id: A0A674N9K9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Adaptor protein complex 2 (AP-2) is a heterotetramer composed of two large adaptins (alpha-type subunit AP2A1 or AP2A2 and beta-type subunit AP2B1), a medium adaptin (mu-type subunit AP2M1) and a small adaptin (sigma-type subunit AP2S1).
messages: Belongs to the adaptor complexes small subunit family.
messages: Cell membrane
messages: coated pit

31033:acp5
gene id: 31033:acp5
uniprot id: H2T6X7
names: Cofactor
messages: Binds 2 iron ions per subunit.

31033:c20h19orf25
gene id: 31033:c20h19orf25
uniprot id: A0A3B5K8X1
names: Similarity
messages: Belongs to the UPF0449 family.

31033:LOC101073205
gene id: 31033:LOC101073205
uniprot id: A0A6D2XZ98
names: Similarity
messages: In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family.
messages: In the N-terminal section; belongs to the glutamate 5-kinase family.

31033:LOC101063742
gene id: 31033:LOC101063742
uniprot id: H2SSZ7
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

31033:LOC101063632
gene id: 31033:LOC101063632
uniprot id: H2TED2
names: Subcellular Location Annotation
messages: cytoskeleton

31033:tmem170a
gene id: 31033:tmem170a
uniprot id: A0A3B5K6M4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM170 family.
messages: Membrane

31033:pex10
gene id: 31033:pex10
uniprot id: A0A674NUB1
names: Function
names: Similarity
messages: Belongs to the pex2/pex10/pex12 family.
messages: Somewhat implicated in the biogenesis of peroxisomes.

31033:LOC101065673
gene id: 31033:LOC101065673
uniprot id: H2UWU3
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

31033:slc25a32
gene id: 31033:slc25a32
uniprot id: A0A3B5KBI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

31033:tm4sf4
gene id: 31033:tm4sf4
uniprot id: H2VCA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L6 tetraspanin family.
messages: Membrane

31033:nup58
gene id: 31033:nup58
uniprot id: H2RTC0
uniprot id: H2RTC3
names: Subcellular Location Annotation
messages: nuclear pore complex

31033:rora
gene id: 31033:rora
uniprot id: A0A674NZT1
uniprot id: H2TPM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

31033:sirt4
gene id: 31033:sirt4
uniprot id: H2UPJ5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sirtuin family. Class II subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Mitochondrion matrix
messages: NAD-dependent protein deacylase. Catalyzes the NAD-dependent hydrolysis of acyl groups from lysine residues.

31033:LOC101072250
gene id: 31033:LOC101072250
uniprot id: H2TWC4
names: Similarity
messages: Belongs to the inositol 3,4-bisphosphate 4-phosphatase family.

31033:LOC101068809
gene id: 31033:LOC101068809
uniprot id: H2VAQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: Cell membrane
messages: Cleavage furrow
messages: Endosome membrane
messages: Midbody ring
messages: Recycling endosome membrane
messages: filopodium membrane
messages: ruffle

31033:LOC101078768
gene id: 31033:LOC101078768
uniprot id: A0A3B5KEC8
names: Similarity
messages: Belongs to the universal ribosomal protein uL23 family.

31033:LOC101061594
gene id: 31033:LOC101061594
uniprot id: A0A674NLH7
names: Subcellular Location Annotation
messages: Membrane

31033:zic5
gene id: 31033:zic5
uniprot id: H2TYM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GLI C2H2-type zinc-finger protein family.
messages: Nucleus

31033:mgmt
gene id: 31033:mgmt
uniprot id: A0A674PQ38
names: Similarity
messages: Belongs to the MGMT family.

31033:rpl7l1
gene id: 31033:rpl7l1
uniprot id: A0A3B5KIU2
names: Similarity
messages: Belongs to the universal ribosomal protein uL30 family.

31033:eif3i
gene id: 31033:eif3i
uniprot id: H2TPH7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit I family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
messages: Cytoplasm

31033:patl1
gene id: 31033:patl1
uniprot id: H2RNJ3
uniprot id: H2RNJ4
names: Similarity
messages: Belongs to the PAT1 family.

31033:ciapin1
gene id: 31033:ciapin1
uniprot id: H2SIK2
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the anamorsin family.
messages: Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex NUBP1-NUBP2. Electrons are transferred to CIAPIN1 from NADPH via the FAD- and FMN-containing protein NDOR1. NDOR1-CIAPIN1 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by providing electrons for reduction during radical cofactor maturation in the catalytic small subunit. Has anti-apoptotic effects in the cell. Involved in negative control of cell death upon cytokine withdrawal. Promotes development of hematopoietic cells.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mitochondrion intermembrane space
messages: Monomer. Interacts with NDOR1. Interacts with CHCHD4.
messages: Nucleus
messages: The C-terminal domain binds 2 Fe-S clusters but is otherwise mostly in an intrinsically disordered conformation.
messages: The N-terminal domain has structural similarity with S-adenosyl-L-methionine-dependent methyltransferases, but does not bind S-adenosyl-L-methionine. It is required for correct assembly of the 2 Fe-S clusters.
messages: The twin Cx2C motifs are involved in the recognition by the mitochondrial CHCHD4/MIA40-GFER/ERV1 disulfide relay system. The formation of 2 disulfide bonds in the Cx2C motifs through dithiol/disulfide exchange reactions effectively traps the protein in the mitochondrial intermembrane space.

31033:gucy1b1
gene id: 31033:gucy1b1
uniprot id: Q90VY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Cytoplasm

31033:LOC101072935
gene id: 31033:LOC101072935
uniprot id: A0A3B5KPW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCR4/nocturin family.
messages: Cytoplasm
messages: Nucleus

31033:supt6h
gene id: 31033:supt6h
uniprot id: A0A3B5KBU6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPT6 family.
messages: Nucleus
messages: Transcription elongation factor that enhances transcription elongation by RNA polymerase II (RNAPII).

31033:myb
gene id: 31033:myb
uniprot id: A0A674NRY4
names: Subcellular Location Annotation
messages: Nucleus

31033:LOC101070821
gene id: 31033:LOC101070821
uniprot id: H2SPZ0
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.

31033:LOC101074463
gene id: 31033:LOC101074463
uniprot id: H2V406
names: Similarity
messages: Belongs to the TGF-beta family.

31033:cdk5
gene id: 31033:cdk5
uniprot id: H2SAY8
names: Similarity
messages: Belongs to the protein kinase superfamily.

31033:mrpl18
gene id: 31033:mrpl18
uniprot id: A0A3B5KJM9
names: Similarity
messages: Belongs to the universal ribosomal protein uL18 family.

31033:LOC101074725
gene id: 31033:LOC101074725
uniprot id: A0A674PPS8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: High affinity receptor for melatonin. The activity of this receptor is mediated by pertussis toxin sensitive G proteins that inhibits adenylate cyclase activity.
messages: Membrane

31033:irak4
gene id: 31033:irak4
uniprot id: A0A3B5K2L4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with MYD88 and IRAK2 to form a ternary complex called the Myddosome.
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. Pelle subfamily.
messages: Cytoplasm
messages: Serine/threonine-protein kinase that plays a critical role in initiating innate immune response against foreign pathogens.

31033:LOC101066436
gene id: 31033:LOC101066436
uniprot id: A0A3B5K9F7
names: Similarity
messages: Belongs to the UPF0046 family.

31033:LOC101062786
gene id: 31033:LOC101062786
uniprot id: H2UQZ6
uniprot id: H2UQZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Cell membrane
messages: Membrane
messages: extracellular exosome

31033:cope
gene id: 31033:cope
uniprot id: H2TXY5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COPE family.
messages: Cytoplasm
messages: Membrane
messages: Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. The coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.

31033:LOC101067225
gene id: 31033:LOC101067225
uniprot id: A0A3B5KE37
names: Similarity
messages: Belongs to the FAM167 (SEC) family.

31033:sox4
gene id: 31033:sox4
uniprot id: Q6WNT3
names: Subcellular Location Annotation
messages: Nucleus

31033:hapln2
gene id: 31033:hapln2
uniprot id: H2SQ78
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

31033:rock1
gene id: 31033:rock1
uniprot id: H2UA39
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by RHOA binding. Inhibited by Y-27632.
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.
messages: Cytoplasm
messages: Homodimer.
messages: Membrane
messages: Protein kinase which is a key regulator of actin cytoskeleton and cell polarity.

31033:ca12
gene id: 31033:ca12
uniprot id: A0A6D2XSH9
names: Function
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

31033:LOC101067994
gene id: 31033:LOC101067994
uniprot id: A0A674N6C4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the band 7/mec-2 family.
messages: Membrane

31033:cnot9
gene id: 31033:cnot9
uniprot id: H2SYI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CNOT9 family.
messages: P-body

31033:cldn7
gene id: 31033:cldn7
uniprot id: A0A3B5KDQ0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

31033:LOC101067966
gene id: 31033:LOC101067966
uniprot id: A0A674PEX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. NADC subfamily.
messages: Membrane

31033:snap25
gene id: 31033:snap25
uniprot id: H2T813
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNAP-25 family.
messages: Cell membrane
messages: Plays an important role in the synaptic function of specific neuronal systems. Associates with proteins involved in vesicle docking and membrane fusion.
messages: synaptosome

31033:tmem267
gene id: 31033:tmem267
uniprot id: A0A3B5K3X5
names: Subcellular Location Annotation
messages: Membrane

31033:LOC101069469
gene id: 31033:LOC101069469
uniprot id: H2SGS8
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: May interact with TSPO.
messages: Mitochondrion
messages: Plays a key role in steroid hormone synthesis by enhancing the metabolism of cholesterol into pregnenolone. Mediates the transfer of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane where it is cleaved to pregnenolone.

31033:LOC101069051
gene id: 31033:LOC101069051
uniprot id: H2TLF6
names: Similarity
messages: Belongs to the WD repeat G protein beta family.

31033:LOC101078604
gene id: 31033:LOC101078604
uniprot id: H2UJB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the reduced folate carrier (RFC) transporter (TC 2.A.48) family.
messages: Membrane

31033:LOC101074127
gene id: 31033:LOC101074127
uniprot id: Q6E5Q9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: tight junction

31033:LOC101063426
gene id: 31033:LOC101063426
uniprot id: H2TNC7
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

31033:LOC101079122
gene id: 31033:LOC101079122
uniprot id: A0A674PB23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

31033:tspan17
gene id: 31033:tspan17
uniprot id: A0A674MP29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

31033:xkr9
gene id: 31033:xkr9
uniprot id: Q5GH45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XK family.
messages: Membrane

31033:adgrl4
gene id: 31033:adgrl4
uniprot id: A0A674NR19
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

31033:thoc7
gene id: 31033:thoc7
uniprot id: A0A674PN97
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the THOC7 family.
messages: Nucleus
messages: Required for efficient export of polyadenylated RNA. Acts as component of the THO subcomplex of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and which specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export to the cytoplasm via the TAP/NFX1 pathway.

31033:wtap
gene id: 31033:wtap
uniprot id: H2SKQ0
names: Similarity
messages: Belongs to the fl(2)d family.

31033:cul5
gene id: 31033:cul5
uniprot id: A0A6D2Y487
names: Similarity
messages: Belongs to the cullin family.

31033:LOC101070473
gene id: 31033:LOC101070473
uniprot id: H2UHI6
names: Subcellular Location Annotation
messages: Membrane

31033:fyn
gene id: 31033:fyn
uniprot id: A0A6D2X158
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

31033:LOC445899
gene id: 31033:LOC445899
uniprot id: Q8QGU8
names: Similarity
messages: Belongs to the pyruvate kinase family.

31033:mrps17
gene id: 31033:mrps17
uniprot id: A0A3B5JYB6
names: Similarity
messages: Belongs to the universal ribosomal protein uS17 family.

31033:LOC101067614
gene id: 31033:LOC101067614
uniprot id: H2SH38
names: Function
names: Similarity
names: Subunit
messages: Acts as a defensive agent. Recognizes blood group fucosylated oligosaccharides including A, B, H and Lewis B-type antigens. Does not recognize Lewis A antigen and has low affinity for monovalent haptens.
messages: Belongs to the fucolectin family.
messages: Homotrimer.

31033:LOC101064581
gene id: 31033:LOC101064581
uniprot id: H2TVT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Golgi apparatus membrane
messages: Recycling endosome
messages: phagosome
messages: trans-Golgi network membrane

31033:nr3c2
gene id: 31033:nr3c2
uniprot id: H2UM26
names: Subcellular Location Annotation
messages: Nucleus

31033:fbxo9
gene id: 31033:fbxo9
uniprot id: H2UN75
names: Subcellular Location Annotation
messages: Cytoplasm

31033:dlx2
gene id: 31033:dlx2
uniprot id: H2V8C6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the distal-less homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

31033:rps11
gene id: 31033:rps11
uniprot id: H2UH24
names: Similarity
messages: Belongs to the universal ribosomal protein uS17 family.

31033:LOC101069964
gene id: 31033:LOC101069964
uniprot id: A0A674PNC2
names: Similarity
messages: Belongs to the Bcl-2 family.

31033:igf2
gene id: 31033:igf2
uniprot id: A0JGX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the insulin family.
messages: Secreted

31033:rbm8a
gene id: 31033:rbm8a
uniprot id: H2U993
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RBM8A family.
messages: Core component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junctions on mRNAs.
messages: Cytoplasm
messages: Heterodimer with MAGOH. Part of the mRNA splicing-dependent exon junction complex (EJC) complex; the core complex contains CASC3, EIF4A3, MAGOH and RBM8A.
messages: Nucleus
messages: Nucleus speckle

31033:e2f1
gene id: 31033:e2f1
uniprot id: H2TU84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the E2F/DP family.
messages: Nucleus

31033:LOC101065545
gene id: 31033:LOC101065545
uniprot id: H2V7M4
names: Similarity
messages: Belongs to the NAC-beta family.

31033:LOC101078401
gene id: 31033:LOC101078401
uniprot id: H2TQY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Endoplasmic reticulum membrane
messages: Membrane

31033:LOC101075840
gene id: 31033:LOC101075840
uniprot id: H2USI4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Cytoplasm
messages: Membrane
messages: Nucleus

31033:LOC101077487
gene id: 31033:LOC101077487
uniprot id: A0A3B5K954
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIB subfamily.
messages: Catalyzes the hydrolysis of ATP coupled with the transport of calcium.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

31033:tspan9
gene id: 31033:tspan9
uniprot id: H2UM51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

31033:rfx2
gene id: 31033:rfx2
uniprot id: H2TBN7
names: Subcellular Location Annotation
messages: Nucleus

31033:LOC101076880
gene id: 31033:LOC101076880
uniprot id: A0A3B5JZ13
names: Similarity
messages: Belongs to the ATG8 family.

31033:LOC101072328
gene id: 31033:LOC101072328
uniprot id: A0A674N168
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

31033:ca6
gene id: 31033:ca6
uniprot id: H2TB98
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reversible hydration of carbon dioxide. Its role in saliva is unknown.
messages: Secreted

31033:igfbp2
gene id: 31033:igfbp2
uniprot id: H2UDH6
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

31033:atp5mc1
gene id: 31033:atp5mc1
uniprot id: Q1KKY5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Membrane
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. A homomeric c-ring of probably 10 subunits is part of the complex rotary element.
messages: Mitochondrion membrane

31033:maf1
gene id: 31033:maf1
uniprot id: A0A3B5KMV2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAF1 family.
messages: Element of the TORC1 signaling pathway that acts as a mediator of diverse signals and that represses RNA polymerase III transcription. Inhibits the de novo assembly of TFIIIB onto DNA.
messages: Nucleus

31033:LOC101078981
gene id: 31033:LOC101078981
uniprot id: A0A3B5KK66
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM134/TMEM230 family.
messages: Early endosome
messages: Endosome
messages: Involved in trafficking and recycling of synaptic vesicles.
messages: Late endosome
messages: Membrane
messages: Recycling endosome
messages: Vesicle
messages: autophagosome
messages: synaptic vesicle
messages: trans-Golgi network

31033:pcnp
gene id: 31033:pcnp
uniprot id: H2V3U7
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Interacts with UHRF2/NIRF.
messages: May be involved in cell cycle regulation.
messages: Nucleus

31033:LOC101074129
gene id: 31033:LOC101074129
uniprot id: A0A3B5KB46
names: Subcellular Location Annotation
messages: Membrane

31033:slc25a40
gene id: 31033:slc25a40
uniprot id: H2SID0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

31033:mc5r
gene id: 31033:mc5r
uniprot id: Q7ZT40
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. This receptor is a possible mediator of the immunomodulation properties of melanocortins.

31033:kcnk3
gene id: 31033:kcnk3
uniprot id: H2V863
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

31033:LOC101076610
gene id: 31033:LOC101076610
uniprot id: H2UBN8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Cell membrane
messages: Protein transport. Probably involved in vesicular traffic.

31033:rpl28
gene id: 31033:rpl28
uniprot id: A0A674MSW0
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL28 family.

31033:LOC101070913
gene id: 31033:LOC101070913
uniprot id: H2V3T0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. LISCH7 family.
messages: Membrane
messages: tight junction

31033:LOC101062674
gene id: 31033:LOC101062674
uniprot id: H2UL13
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

31033:LOC101072667
gene id: 31033:LOC101072667
uniprot id: A0A674MYX7
names: Similarity
messages: Belongs to the Gfo/Idh/MocA family.

31033:LOC101075419
gene id: 31033:LOC101075419
uniprot id: H2SXX9
names: Subcellular Location Annotation
messages: Nucleus

31033:tp53rk
gene id: 31033:tp53rk
uniprot id: A0A674NJ29
names: Similarity
messages: Belongs to the protein kinase superfamily. BUD32 family.

31033:ptar1
gene id: 31033:ptar1
uniprot id: A0A674NHW1
names: Similarity
messages: Belongs to the protein prenyltransferase subunit alpha family.

31033:slc26a5
gene id: 31033:slc26a5
uniprot id: A0A674MFI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

31033:LOC101072768
gene id: 31033:LOC101072768
uniprot id: Q1KKY0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

31033:LOC101071876
gene id: 31033:LOC101071876
uniprot id: H2TW85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-alpha family. G(12) subfamily.
messages: Membrane

31033:tas2r1
gene id: 31033:tas2r1
uniprot id: Q2MHJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor T2R family.
messages: Membrane

31033:trpv6
gene id: 31033:trpv6
uniprot id: Q7T2Z4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

31033:dpyd
gene id: 31033:dpyd
uniprot id: A0A674NX04
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the dihydropyrimidine dehydrogenase family.
messages: Binds 4 [4Fe-4S] clusters. Contains approximately 16 iron atoms per subunit.
messages: Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine.

31033:alx3
gene id: 31033:alx3
uniprot id: H2S3V9
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

31033:shh
gene id: 31033:shh
uniprot id: Q8AXT0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the hedgehog family.
messages: Cell membrane
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Membrane
messages: Multimer.
messages: The C-terminal part of the hedgehog protein precursor displays an autoproteolysis activity that results in the cleavage of the full-length protein into two parts (N-product and C-product). In addition, the C-terminal part displays a cholesterol transferase activity that results by the covalent attachment of a cholesterol moiety to the C-terminal of the newly generated N-product.
messages: The dually lipidated hedgehog protein N-product is a morphogen which is essential for a variety of patterning events during development.

31033:borcs8
gene id: 31033:borcs8
uniprot id: A0A3B5K6L9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BORCS8 family.
messages: Lysosome membrane
messages: Membrane

31033:LOC101074489
gene id: 31033:LOC101074489
uniprot id: H2T3W8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

31033:LOC101074686
gene id: 31033:LOC101074686
uniprot id: Q5H719
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Toll-like receptor family.
messages: Membrane

31033:dok7
gene id: 31033:dok7
uniprot id: Q18PD9
names: Domain
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Probable muscle-intrinsic activator of MUSK that plays an essential role in neuromuscular synaptogenesis. Acts in aneural activation of MUSK and subsequent acetylcholine receptor (AchR) clustering in myotubes (By similarity).
messages: Synapse
messages: The PH domain mediated binding to phospholipids with phosphoinositol headgroups. Affinity is highest for phosphatidyl 3,4,5-trisphosphate, followed by phosphatidylinositol 3,4-bisphosphate and phosphatidylinositol 4,5-bisphosphate (By similarity).

31033:gdpd1
gene id: 31033:gdpd1
uniprot id: H2SZF7
names: Similarity
messages: Belongs to the glycerophosphoryl diester phosphodiesterase family.

31033:LOC445956
gene id: 31033:LOC445956
uniprot id: H2U643
names: Similarity
messages: Belongs to the NRAMP family.

31033:camk2n2
gene id: 31033:camk2n2
uniprot id: A0A3B5KFL5
names: Similarity
messages: Belongs to the CAMK2N family.

31033:LOC101076568
gene id: 31033:LOC101076568
uniprot id: H2UXT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Cell membrane
messages: Cytoplasmic vesicle
messages: Endosome
messages: Membrane
messages: Perikaryon
messages: Recycling endosome
messages: Synaptic cell membrane
messages: Vesicle
messages: dendrite

31033:LOC101071993
gene id: 31033:LOC101071993
uniprot id: H2SMW3
names: Similarity
messages: Belongs to the phosphatase 2A regulatory subunit B56 family.

31033:sgms2
gene id: 31033:sgms2
uniprot id: H2T7F5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sphingomyelin synthase family.
messages: Membrane

31033:LOC101062630
gene id: 31033:LOC101062630
uniprot id: H2V4M9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: cilium membrane

31033:camsap1
gene id: 31033:camsap1
uniprot id: H2UZN3
names: Domain
names: Similarity
messages: Belongs to the CAMSAP1 family.
messages: The CKK domain binds microtubules.

31033:gchfr
gene id: 31033:gchfr
uniprot id: A0A3B5KIQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GFRP family.
messages: Membrane
messages: Nucleus membrane
messages: cytosol

31033:suz12
gene id: 31033:suz12
uniprot id: H2U1A3
names: Similarity
messages: Belongs to the VEFS (VRN2-EMF2-FIS2-SU(Z)12) family.

31033:LOC101069829
gene id: 31033:LOC101069829
uniprot id: A0A3B5K8T5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tumor necrosis factor family.
messages: Membrane
messages: Secreted

31033:aspa
gene id: 31033:aspa
uniprot id: H2RVG4
names: Cofactor
names: Similarity
messages: Belongs to the AspA/AstE family. Aspartoacylase subfamily.
messages: Binds 1 zinc ion per subunit.

31033:kit
gene id: 31033:kit
uniprot id: A0A674MR93
uniprot id: Q8AXC6
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Autophosphorylated on tyrosine residues. Phosphorylated tyrosine residues are important for interaction with specific binding partners (By similarity).
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
messages: Cell membrane
messages: Membrane
messages: Tyrosine-protein kinase that acts as cell-surface receptor for the cytokine kitlg/scf and plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis.
messages: Ubiquitinated. Rapidly ubiquitinated after autophosphorylation induced by kitlg/scf binding, leading to internalization and degradation.

31033:LOC101070245
gene id: 31033:LOC101070245
uniprot id: H2S0M9
names: Similarity
messages: Belongs to the RAPGEF2 family.

31033:rbm15
gene id: 31033:rbm15
uniprot id: H2S341
names: Similarity
messages: Belongs to the RRM Spen family.

31033:tlx1
gene id: 31033:tlx1
uniprot id: H2RLJ9
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

31033:slain1
gene id: 31033:slain1
uniprot id: A0A3B5KHY8
names: Similarity
messages: Belongs to the SLAIN motif-containing family.

31033:bloc1s1
gene id: 31033:bloc1s1
uniprot id: A0A3B5KDZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BLOC1S1 family.
messages: Mitochondrion intermembrane space

31033:efnb1
gene id: 31033:efnb1
uniprot id: A0A674MRV3
names: Caution
names: Similarity
messages: Belongs to the ephrin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

31033:pigl
gene id: 31033:pigl
uniprot id: H2RNB7
names: Function
names: Similarity
messages: Belongs to the PIGL family.
messages: Involved in the second step of GPI biosynthesis. De-N-acetylation of N-acetylglucosaminyl-phosphatidylinositol.

31033:LOC101075961
gene id: 31033:LOC101075961
uniprot id: A0A3B5K1P7
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.

31033:ddx6
gene id: 31033:ddx6
uniprot id: A0A3B5KEL6
names: Similarity
messages: Belongs to the DEAD box helicase family.

31033:prdm13
gene id: 31033:prdm13
uniprot id: H2RKU8
names: Subcellular Location Annotation
messages: Nucleus

31033:LOC101075265
gene id: 31033:LOC101075265
uniprot id: A0A674NZA7
names: Subcellular Location Annotation
messages: Membrane

31033:LOC101066598
gene id: 31033:LOC101066598
uniprot id: H2UK77
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

31033:tmco1
gene id: 31033:tmco1
uniprot id: A0A674MH78
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMCO1 family.
messages: Calcium-selective channel required to prevent calcium stores from overfilling.
messages: Endoplasmic reticulum membrane
messages: Membrane

31033:svop
gene id: 31033:svop
uniprot id: H2UJ37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily.
messages: Membrane

31033:sbno1
gene id: 31033:sbno1
uniprot id: A0A3B5KA72
names: Similarity
messages: Belongs to the SBNO family.

31033:six1
gene id: 31033:six1
uniprot id: H2TQH5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SIX/Sine oculis homeobox family.
messages: Cytoplasm
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

31033:paics
gene id: 31033:paics
uniprot id: A0A674MC30
names: Similarity
names: Subunit
messages: Homooctamer.
messages: In the C-terminal section; belongs to the AIR carboxylase family. Class II subfamily.
messages: In the N-terminal section; belongs to the SAICAR synthetase family.

31033:qtrt1
gene id: 31033:qtrt1
uniprot id: H2UB86
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Catalytic subunit of the queuine tRNA-ribosyltransferase (TGT) that catalyzes the base-exchange of a guanine (G) residue with queuine (Q) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming queuine, allowing a nucleophilic attack on the C1' of the ribose to form the product.
messages: Cytoplasm
messages: Heterodimer of a catalytic subunit QTRT1 and an accessory subunit QTRT2.
messages: Mitochondrion outer membrane

31033:LOC101068543
gene id: 31033:LOC101068543
uniprot id: H2SK65
names: Subcellular Location Annotation
messages: Nucleus

31033:ndufb10
gene id: 31033:ndufb10
uniprot id: A0A674MYJ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit that is involved in the functional assembly of the mitochondrial respiratory chain complex I. Complex I has an NADH dehydrogenase activity with ubiquinone as an immediate electron acceptor and mediates the transfer of electrons from NADH to the respiratory chain.
messages: Belongs to the complex I NDUFB10 subunit family.
messages: Mitochondrion inner membrane

31033:pik3ca
gene id: 31033:pik3ca
uniprot id: H2SAV2
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.

31033:LOC101079934
gene id: 31033:LOC101079934
uniprot id: A0A674NYW8
names: Similarity
messages: Belongs to the DNA photolyase class-1 family.

31033:tspan15
gene id: 31033:tspan15
uniprot id: A0A3B5K392
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

31033:cand1
gene id: 31033:cand1
uniprot id: H2SPV9
names: Similarity
messages: Belongs to the CAND family.

31033:LOC101062439
gene id: 31033:LOC101062439
uniprot id: A0A674N7E2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

31033:LOC101075515
gene id: 31033:LOC101075515
uniprot id: A0A674NB52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptogyrin family.
messages: Membrane

31033:slc50a1
gene id: 31033:slc50a1
uniprot id: H2SYZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SWEET sugar transporter family.
messages: Membrane

31033:ttc39a
gene id: 31033:ttc39a
uniprot id: A0A674MUT4
names: Similarity
messages: Belongs to the TTC39 family.

31033:lcor
gene id: 31033:lcor
uniprot id: H2SRP1
names: Subcellular Location Annotation
messages: Nucleus

31033:LOC101066411
gene id: 31033:LOC101066411
uniprot id: A0A674MCF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the akirin family.
messages: Nucleus

31033:LOC101066824
gene id: 31033:LOC101066824
uniprot id: A0A674P714
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

31033:tmem70
gene id: 31033:tmem70
uniprot id: A0A674NTK9
names: Similarity
messages: Belongs to the TMEM70 family.

31033:myf5
gene id: 31033:myf5
uniprot id: Q6SYV6
names: Subcellular Location Annotation
names: Subunit
messages: Efficient DNA binding requires dimerization with another bHLH protein.
messages: Nucleus

31033:rnft2
gene id: 31033:rnft2
uniprot id: H2UYB3
names: Subcellular Location Annotation
messages: Membrane

31033:LOC101067317
gene id: 31033:LOC101067317
uniprot id: H2T857
names: Similarity
messages: Belongs to the Luc7 family.

31033:cnr1
gene id: 31033:cnr1
uniprot id: Q98894
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: G-protein coupled receptor for cannabinoids (By similarity). Mediates many cannabinoid-induced effects in the central nervous system (CNS), as well as in peripheral tissues (By similarity). Regulates cellular respiration and energy production in response to cannabinoids (By similarity). Signaling typically involves reduction in cyclic AMP (By similarity).
messages: Mitochondrion outer membrane
messages: Palmitoylation at Cys-414 is important for recruitment at both plasma membrane and lipid rafts and association with G protein alpha subunits.
messages: Presynapse
messages: axon

31033:LOC101065968
gene id: 31033:LOC101065968
uniprot id: A0A674P0L2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFIIF alpha subunit family.
messages: Nucleus
messages: TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation.

31033:selenoi
gene id: 31033:selenoi
uniprot id: A0A3B5KE84
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

31033:LOC101065671
gene id: 31033:LOC101065671
uniprot id: H2TSQ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cyclin family. Cyclin AB subfamily.
messages: Essential for the control of the cell cycle at the G2/M (mitosis) transition.
messages: Interacts with the CDK1 protein kinase to form a serine/threonine kinase holoenzyme complex also known as maturation promoting factor (MPF). The cyclin subunit imparts substrate specificity to the complex.

31033:drd2
gene id: 31033:drd2
uniprot id: P53453
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Receptor for dopamine.

31033:LOC101070710
gene id: 31033:LOC101070710
uniprot id: H2RLZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel CLIC family.
messages: Membrane

31033:LOC101063462
gene id: 31033:LOC101063462
uniprot id: H2TA80
names: Similarity
messages: Belongs to the adenosylhomocysteinase family.

31033:folh1b
gene id: 31033:folh1b
uniprot id: H2T9B8
uniprot id: H2T9B9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M28 family. M28B subfamily.
messages: Cell membrane
messages: Membrane

31033:LOC101071843
gene id: 31033:LOC101071843
uniprot id: H2SDA8
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

31033:otop1
gene id: 31033:otop1
uniprot id: Q7M555
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the otopetrin family.
messages: Cell membrane
messages: Membrane

31033:neurod2
gene id: 31033:neurod2
uniprot id: H2UX28
names: Subcellular Location Annotation
messages: Nucleus

31033:LOC101075639
gene id: 31033:LOC101075639
uniprot id: H2T101
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

31033:LOC101068976
gene id: 31033:LOC101068976
uniprot id: H2TCL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

31033:c8h4orf48
gene id: 31033:c8h4orf48
uniprot id: H2SIK4
names: Subcellular Location Annotation
messages: Secreted

31033:cdv3
gene id: 31033:cdv3
uniprot id: H2STJ3
names: Similarity
messages: Belongs to the CDV3 family.

31033:LOC101063161
gene id: 31033:LOC101063161
uniprot id: H2SUR8
names: Similarity
messages: Belongs to the DNase II family.

31033:LOC446072
gene id: 31033:LOC446072
uniprot id: Q804X2
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular space

31033:tns4
gene id: 31033:tns4
uniprot id: A0A674P595
names: Similarity
messages: Belongs to the PTEN phosphatase protein family.

31033:vipr1
gene id: 31033:vipr1
uniprot id: A0A674MA68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family.
messages: Cell membrane
messages: Membrane

31033:LOC101066693
gene id: 31033:LOC101066693
uniprot id: Q802A3
names: Similarity
messages: Belongs to the globin family.

31033:cacfd1
gene id: 31033:cacfd1
uniprot id: A0A674PL65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calcium channel flower family.
messages: Membrane

31033:LOC101071466
gene id: 31033:LOC101071466
uniprot id: A0A674N8K8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Orai family.
messages: Membrane

31033:LOC101074651
gene id: 31033:LOC101074651
uniprot id: H2SK97
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

31033:rap2c
gene id: 31033:rap2c
uniprot id: A0A674N6S9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Ras family.
messages: Endosome membrane
messages: Recycling endosome membrane

31033:rab9b
gene id: 31033:rab9b
uniprot id: H2TED5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: phagosome membrane

31033:uchl3
gene id: 31033:uchl3
uniprot id: H2TQ79
names: Similarity
messages: Belongs to the peptidase C12 family.

31033:ebp
gene id: 31033:ebp
uniprot id: H2U6T9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EBP family.
messages: Endoplasmic reticulum membrane
messages: Membrane

31033:LOC101073638
gene id: 31033:LOC101073638
uniprot id: A0A674PH27
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

31033:cnp-3
gene id: 31033:cnp-3
uniprot id: Q805D4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the natriuretic peptide family.
messages: Exhibits natriuretic and vasodepressant activity. Has cGMP-stimulating activity. May help to regulate body fluid homeostasis in a variety of aquatic environments.
messages: Secreted

31033:LOC101064922
gene id: 31033:LOC101064922
uniprot id: H2V4X7
names: Similarity
messages: Belongs to the TMEM178 family.

31033:rbbp4
gene id: 31033:rbbp4
uniprot id: A0A674N6J1
names: Subcellular Location Annotation
messages: Nucleus

31033:LOC101063537
gene id: 31033:LOC101063537
uniprot id: H2TQ33
names: Subcellular Location Annotation
messages: Membrane

31033:anp32a
gene id: 31033:anp32a
uniprot id: A0A674P2H4
names: Similarity
messages: Belongs to the ANP32 family.

31033:LOC101074187
gene id: 31033:LOC101074187
uniprot id: H2UPM1
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

31033:LOC101073879
gene id: 31033:LOC101073879
uniprot id: A0A674PKE0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SIX/Sine oculis homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

31033:LOC101065176
gene id: 31033:LOC101065176
uniprot id: A0A674MWG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERD2 family.
messages: COPI-coated vesicle membrane
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Membrane

31033:LOC101071476
gene id: 31033:LOC101071476
uniprot id: H2S7A9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Endosome
messages: Late endosome
messages: Membrane

31033:LOC101062737
gene id: 31033:LOC101062737
uniprot id: A0A674MP83
names: Subcellular Location Annotation
messages: cytosol

31033:LOC101063855
gene id: 31033:LOC101063855
uniprot id: H2TFV9
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

31033:LOC101077129
gene id: 31033:LOC101077129
uniprot id: H2U005
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Bcl-2 family.
messages: Membrane

31033:LOC101073971
gene id: 31033:LOC101073971
uniprot id: H2RL21
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

31033:irf2
gene id: 31033:irf2
uniprot id: H2RVT3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IRF family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

31033:kpna6
gene id: 31033:kpna6
uniprot id: H2TLL4
names: Similarity
messages: Belongs to the importin alpha family.

31033:idnk
gene id: 31033:idnk
uniprot id: A0A674MYG4
names: Similarity
messages: Belongs to the gluconokinase GntK/GntV family.

31033:flot1
gene id: 31033:flot1
uniprot id: A0A674NGH2
uniprot id: A1KZS6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. Flotillin subfamily.
messages: Endosome
messages: Heterooligomeric complex.
messages: Membrane

31033:ptpn2
gene id: 31033:ptpn2
uniprot id: H2U2M3
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class 1 subfamily.

31033:lrp3
gene id: 31033:lrp3
uniprot id: H2TG01
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

31033:pitx1
gene id: 31033:pitx1
uniprot id: A0A674PJ71
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family. Bicoid subfamily.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

31033:tor3a
gene id: 31033:tor3a
uniprot id: H2SHJ6
names: Similarity
messages: Belongs to the ClpA/ClpB family. Torsin subfamily.

31033:LOC101065572
gene id: 31033:LOC101065572
uniprot id: H2URW4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

31033:LOC101070482
gene id: 31033:LOC101070482
uniprot id: A0A674NQZ0
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

31033:itgb6
gene id: 31033:itgb6
uniprot id: H2V421
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin beta chain family.
messages: Membrane

31033:fgfr2
gene id: 31033:fgfr2
uniprot id: H2V7F6
uniprot id: H2V7F7
uniprot id: H2V7F8
uniprot id: H2V7F9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. Fibroblast growth factor receptor subfamily.
messages: Cell membrane
messages: Membrane

31033:srsf1
gene id: 31033:srsf1
uniprot id: H2S8C5
names: Similarity
messages: Belongs to the splicing factor SR family.

31033:ndel1
gene id: 31033:ndel1
uniprot id: H2TPJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nudE family.
messages: centrosome
messages: spindle

31033:sf3a1
gene id: 31033:sf3a1
uniprot id: H2SR29
names: Subcellular Location Annotation
messages: Nucleus

31033:LOC101064679
gene id: 31033:LOC101064679
uniprot id: H2UUX5
names: Similarity
messages: Belongs to the G-alpha family. G(q) subfamily.

31033:hal
gene id: 31033:hal
uniprot id: H2V2G0
names: Similarity
messages: Belongs to the PAL/histidase family.

31033:LOC101062380
gene id: 31033:LOC101062380
uniprot id: A0A674NR87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: Cytoplasm

31033:hspb1
gene id: 31033:hspb1
uniprot id: A0A674PKS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small heat shock protein (HSP20) family.
messages: spindle

31033:LOC101076518
gene id: 31033:LOC101076518
uniprot id: A0A3B5KTB6
names: Similarity
messages: Belongs to the SH3BGR family.

31033:LOC101065354
gene id: 31033:LOC101065354
uniprot id: Q7SZG2
names: Subcellular Location Annotation
messages: Secreted

31033:ggt1
gene id: 31033:ggt1
uniprot id: H2UXU8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaves the gamma-glutamyl peptide bond of glutathione and glutathione conjugates.
messages: Membrane

31033:snrpd2
gene id: 31033:snrpd2
uniprot id: A0A3B5KI36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP core protein family.
messages: Nucleus
messages: cytosol

31033:kpna3
gene id: 31033:kpna3
uniprot id: H2UN31
names: Similarity
messages: Belongs to the importin alpha family.

31033:alcam
gene id: 31033:alcam
uniprot id: A0S0K9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: axon
messages: dendrite

31033:slc25a5
gene id: 31033:slc25a5
uniprot id: Q5KSP2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Catalyzes the exchange of ADP and ATP across the membrane.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Monomer.

31033:LOC101071510
gene id: 31033:LOC101071510
uniprot id: H2TUN8
names: Similarity
messages: Belongs to the bZIP family. Maf subfamily.

31033:sox14
gene id: 31033:sox14
uniprot id: Q6WNT8
names: Subcellular Location Annotation
messages: Nucleus

31033:LOC101061350
gene id: 31033:LOC101061350
uniprot id: A0A674MPG4
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Belongs to the annexin family.
messages: Membrane
messages: basement membrane

31033:LOC101080153
gene id: 31033:LOC101080153
uniprot id: H2SQ99
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase.

31033:npffr2
gene id: 31033:npffr2
uniprot id: Q05KN3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for NPAF (A-18-F-amide) and NPFF (F-8-F-amide) neuropeptides, also known as morphine-modulating peptides. Can also be activated by a variety of naturally occurring or synthetic FMRF-amide like ligands. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.

31033:LOC101067200
gene id: 31033:LOC101067200
uniprot id: A0A674NJ85
names: Similarity
messages: Belongs to the yippee family.

31033:LOC101074178
gene id: 31033:LOC101074178
uniprot id: A0A3B5KJW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BUD31 (G10) family.
messages: Nucleus

31033:LOC101064057
gene id: 31033:LOC101064057
uniprot id: A0A674NIL6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neuropilin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

31033:copg2
gene id: 31033:copg2
uniprot id: H2UTW1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COPG family.
messages: COPI-coated vesicle membrane
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Membrane
messages: Oligomeric complex.
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.

31033:papss1
gene id: 31033:papss1
uniprot id: H2T595
names: Similarity
messages: In the C-terminal section; belongs to the sulfate adenylyltransferase family.
messages: In the N-terminal section; belongs to the APS kinase family.

31033:LOC101075762
gene id: 31033:LOC101075762
uniprot id: A0A674NXT9
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

31033:LOC101079259
gene id: 31033:LOC101079259
uniprot id: A0A674NSP6
names: Similarity
messages: Belongs to the PPDPF family.

31033:txnrd2
gene id: 31033:txnrd2
uniprot id: H2UF24
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

31033:LOC101076691
gene id: 31033:LOC101076691
uniprot id: A0A3B5K6B9
names: Similarity
messages: Belongs to the Bcl-2 family.

31033:fut9c
gene id: 31033:fut9c
uniprot id: Q70AG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 10 family.
messages: Golgi stack membrane

31033:znf711
gene id: 31033:znf711
uniprot id: A0A3B5KK06
names: Subcellular Location Annotation
messages: Nucleus

31033:LOC101066863
gene id: 31033:LOC101066863
uniprot id: H2UT22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

31033:strn
gene id: 31033:strn
uniprot id: H2SKF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat striatin family.
messages: Membrane

31033:LOC101064464
gene id: 31033:LOC101064464
uniprot id: H2TWW8
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

31033:LOC101073955
gene id: 31033:LOC101073955
uniprot id: H2SE86
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

31033:st8sia3
gene id: 31033:st8sia3
uniprot id: Q6KC07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

31033:LOC101063134
gene id: 31033:LOC101063134
uniprot id: A0A674PPC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CLPTM1 family.
messages: Membrane

31033:LOC101074872
gene id: 31033:LOC101074872
uniprot id: H2UCM8
names: Similarity
messages: Belongs to the GDNFR family.

31033:gpn2
gene id: 31033:gpn2
uniprot id: H2UA84
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GPN-loop GTPase family.
messages: Binds to RNA polymerase II (RNAPII).
messages: Small GTPase required for proper localization of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import.

31033:LOC101073618
gene id: 31033:LOC101073618
uniprot id: A0A3B5KGF8
names: Subcellular Location Annotation
messages: Membrane
messages: cytoskeleton

31033:apip
gene id: 31033:apip
uniprot id: H2UX72
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aldolase class II family. Adducin subfamily.
messages: Belongs to the aldolase class II family. MtnB subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Functions in the methionine salvage pathway. May play a role in apoptosis.
messages: Cytoplasm

31033:dennd6a
gene id: 31033:dennd6a
uniprot id: A0A3B5JZ83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DENND6 family.
messages: Endosome
messages: Recycling endosome

31033:galnt9
gene id: 31033:galnt9
uniprot id: A0A674M8N8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

31033:mettl1
gene id: 31033:mettl1
uniprot id: H2VDV7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Forms a complex with WDR4.
messages: Nucleus

31033:LOC101062076
gene id: 31033:LOC101062076
uniprot id: P53480
names: Function
names: Miscellaneous
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
names: Tissue Specificity
messages: Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.
messages: Belongs to the actin family.
messages: In vertebrates 3 main groups of actin isoforms, alpha, beta and gamma have been identified. The alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. The beta and gamma actins coexist in most cell types as components of the cytoskeleton and as mediators of internal cell motility.
messages: Monomethylation at Lys-86 (K86me1) regulates actin-myosin interaction and actomyosin-dependent processes. Demethylation by ALKBH4 is required for maintaining actomyosin dynamics supporting normal cleavage furrow ingression during cytokinesis and cell migration.
messages: Oxidation of Met-46 and Met-49 by MICALs (MICAL1, MICAL2 or MICAL3) to form methionine sulfoxide promotes actin filament depolymerization. MICAL1 and MICAL2 produce the (R)-S-oxide form. The (R)-S-oxide form is reverted by MSRB1 and MSRB2, which promotes actin repolymerization.
messages: Polymerization of globular actin (G-actin) leads to a structural filament (F-actin) in the form of a two-stranded helix. Each actin can bind to 4 others.
messages: Predominantly expressed in heart. Lower levels in skeletal muscle and skin.
messages: There are three genes coding for cardiac actin in Fugu.
messages: cytoskeleton

31033:LOC101072897
gene id: 31033:LOC101072897
uniprot id: H2V3T7
names: Similarity
messages: Belongs to the TGF-beta family.

31033:LOC101080185
gene id: 31033:LOC101080185
uniprot id: H2TKX0
names: Similarity
messages: Belongs to the peptidase M24 family.

31033:ugp2
gene id: 31033:ugp2
uniprot id: A0A674PDB3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UDPGP type 1 family.
messages: Homooctamer.
messages: UTP--glucose-1-phosphate uridylyltransferase catalyzing the conversion of glucose-1-phosphate into UDP-glucose, a crucial precursor for the production of glycogen.

31033:pcmt1
gene id: 31033:pcmt1
uniprot id: H2RSL9
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

31033:atp8a1
gene id: 31033:atp8a1
uniprot id: A0A674N6L3
uniprot id: H2UEP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

31033:mrpl51
gene id: 31033:mrpl51
uniprot id: A0A3B5KGF6
names: Similarity
messages: Belongs to the mitochondrion-specific ribosomal protein mL51 family.

31033:chst10
gene id: 31033:chst10
uniprot id: H2SZP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 2 family.
messages: Golgi apparatus membrane
messages: Membrane

31033:kif1bp
gene id: 31033:kif1bp
uniprot id: H2RTB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KIF-binding protein family.
messages: cytoskeleton

31033:LOC101065022
gene id: 31033:LOC101065022
uniprot id: H2T241
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Bcl-2 family.
messages: Membrane

31033:ndrg2
gene id: 31033:ndrg2
uniprot id: H2S287
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NDRG family.
messages: Contributes to the regulation of the Wnt signaling pathway. Down-regulates CTNNB1-mediated transcriptional activation of target genes. May be involved in neuron differentiation.
messages: Cytoplasm

31033:LOC101078546
gene id: 31033:LOC101078546
uniprot id: H2V4K9
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

31033:LOC101074205
gene id: 31033:LOC101074205
uniprot id: H2TEA4
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

31033:LOC101071288
gene id: 31033:LOC101071288
uniprot id: A0A3B5K7Q8
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family.

31033:naxe
gene id: 31033:naxe
uniprot id: H2U9Q0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NnrE/AIBP family.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mitochondrion
messages: Secreted

31033:LOC101068534
gene id: 31033:LOC101068534
uniprot id: H2UIK1
names: Similarity
messages: Belongs to the thioesterase PaaI family.

31033:tp63
gene id: 31033:tp63
uniprot id: H2S6K4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes.
messages: Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression.
messages: Belongs to the p53 family.
messages: Binds 1 zinc ion per subunit.
messages: Binds DNA as a homotetramer. Isoform composition of the tetramer may determine transactivation activity.
messages: Cytoplasm
messages: Nucleus

31033:tmem170b
gene id: 31033:tmem170b
uniprot id: A0A3B5KR21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM170 family.
messages: Membrane

31033:LOC101075767
gene id: 31033:LOC101075767
uniprot id: A0A674PJM8
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

31033:LOC101072739
gene id: 31033:LOC101072739
uniprot id: Q2PR14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

31033:traf4
gene id: 31033:traf4
uniprot id: A0A3B5KJY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TNF receptor-associated factor family.
messages: Cytoplasm

31033:LOC101073277
gene id: 31033:LOC101073277
uniprot id: A0A674PE33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ubiquitin family. SUMO subfamily.
messages: Nucleus

31033:pacap1a
gene id: 31033:pacap1a
uniprot id: Q5WML1
names: Subcellular Location Annotation
messages: Membrane

31033:LOC101071471
gene id: 31033:LOC101071471
uniprot id: A0A3B5JWB8
uniprot id: A0A3B5KG23
names: Similarity
messages: Belongs to the EF-1-beta/EF-1-delta family.

31033:ctnnbl1
gene id: 31033:ctnnbl1
uniprot id: A0A674NZC3
names: Subcellular Location Annotation
messages: Nucleus

31033:LOC101076407
gene id: 31033:LOC101076407
uniprot id: A0A674NGP5
names: Similarity
messages: Belongs to the peptidase S1C family.

31033:pdyn
gene id: 31033:pdyn
uniprot id: H2U1J9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the opioid neuropeptide precursor family.
messages: Dynorphin peptides differentially regulate the kappa opioid receptor. Dynorphin A(1-13) has a typical opiod activity, it is 700 times more potent than Leu-enkephalin.
messages: Leu-enkephalins compete with and mimic the effects of opiate drugs. They play a role in a number of physiologic functions, including pain perception and responses to stress.
messages: Leumorphin has a typical opiod activity and may have anti-apoptotic effect.
messages: Secreted

31033:LOC101078155
gene id: 31033:LOC101078155
uniprot id: A0A674P329
names: Similarity
messages: Belongs to the intermediate filament family.

31033:LOC101073198
gene id: 31033:LOC101073198
uniprot id: A0A674NZL5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

31033:pln
gene id: 31033:pln
uniprot id: A0A3B5KC38
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phospholamban family.
messages: Endoplasmic reticulum membrane
messages: Homopentamer.
messages: Membrane
messages: Mitochondrion membrane
messages: Reversibly inhibits the activity of ATP2A2 in cardiac sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca(2+). Modulates the contractility of the heart muscle in response to physiological stimuli via its effects on ATP2A2. Modulates calcium re-uptake during muscle relaxation and plays an important role in calcium homeostasis in the heart muscle. The degree of ATP2A2 inhibition depends on the oligomeric state of PLN.
messages: Sarcoplasmic reticulum membrane

31033:aff4
gene id: 31033:aff4
uniprot id: A0A674NTE1
uniprot id: H2T674
names: Similarity
messages: Belongs to the AF4 family.

31033:phyhipl
gene id: 31033:phyhipl
uniprot id: H2TBP2
names: Similarity
messages: Belongs to the PHYHIP family.

31033:ncbp2
gene id: 31033:ncbp2
uniprot id: A0A674N766
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RRM NCBP2 family.
messages: Component of the cap-binding complex (CBC), which binds co-transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense-mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U snRNA and intronless mRNAs export from the nucleus. The CBC complex is essential for a pioneer round of mRNA translation, before steady state translation when the CBC complex is replaced by cytoplasmic cap-binding protein eIF4E. The pioneer round of mRNA translation mediated by the CBC complex plays a central role in nonsense-mediated mRNA decay (NMD), NMD only taking place in mRNAs bound to the CBC complex, but not on eIF4E-bound mRNAs. The CBC complex enhances NMD in mRNAs containing at least one exon-junction complex (EJC), promoting the interaction between upf1 and upf2. The CBC complex is also involved in 'failsafe' NMD, which is independent of the EJC complex, while it does not participate in Staufen-mediated mRNA decay (SMD). During cell proliferation, the CBC complex is also involved in microRNAs (miRNAs) biogenesis via its interaction with srrt/ars2, thereby being required for miRNA-mediated RNA interference. The CBC complex also acts as a negative regulator of parn, thereby acting as an inhibitor of mRNA deadenylation. In the CBC complex, ncbp2/cbp20 recognizes and binds capped RNAs (m7GpppG-capped RNA) but requires ncbp1/cbp80 to stabilize the movement of its N-terminal loop and lock the CBC into a high affinity cap-binding state with the cap structure. The conventional cap-binding complex with NCBP2 binds both small nuclear RNA (snRNA) and messenger (mRNA) and is involved in their export from the nucleus.
messages: Component of the nuclear cap-binding complex (CBC), a heterodimer composed of ncbp1/cbp80 and ncbp2/cbp20 that interacts with m7GpppG-capped RNA.
messages: Nucleus

31033:LOC101070467
gene id: 31033:LOC101070467
uniprot id: A0A3B5KNF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

31033:psat1
gene id: 31033:psat1
uniprot id: H2RNU2
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.

31033:hsp90b1
gene id: 31033:hsp90b1
uniprot id: H2V2R8
names: Similarity
messages: Belongs to the heat shock protein 90 family.

31033:nkx2-1
gene id: 31033:nkx2-1
uniprot id: H2TZH3
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

31033:atp5f1d
gene id: 31033:atp5f1d
uniprot id: H2VAT0
names: Similarity
messages: Belongs to the ATPase epsilon chain family.

31033:nkx2-8
gene id: 31033:nkx2-8
uniprot id: Q9DDW2
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

31033:gpsm1
gene id: 31033:gpsm1
uniprot id: H2SXN9
names: Similarity
messages: Belongs to the GPSM family.

31033:LOC101078102
gene id: 31033:LOC101078102
uniprot id: A0A674MKD7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

31033:ing1
gene id: 31033:ing1
uniprot id: A0A3B5KBY9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ING family.
messages: Component of an histone acetyltransferase complex.
messages: Component of an histone acetyltransferase complex. Interacts with H3K4me3 and to a lesser extent with H3K4me2.
messages: Nucleus
messages: The PHD-type zinc finger mediates the binding to H3K4me3.

31033:LOC101072887
gene id: 31033:LOC101072887
uniprot id: H2TRU5
names: Subcellular Location Annotation
messages: Membrane

31033:chmp2b
gene id: 31033:chmp2b
uniprot id: H2SAE2
names: Similarity
messages: Belongs to the SNF7 family.

31033:b4galt7
gene id: 31033:b4galt7
uniprot id: Q2HPN2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 7 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids.

31033:LOC101067604
gene id: 31033:LOC101067604
uniprot id: H2SQS0
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.

31033:LOC101069249
gene id: 31033:LOC101069249
uniprot id: A0A3B5K6I0
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. PHOSPHO family.

31033:LOC101071975
gene id: 31033:LOC101071975
uniprot id: A0A674PRS7
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. RAC subfamily.

31033:hlf
gene id: 31033:hlf
uniprot id: H2S8P0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. PAR subfamily.
messages: Nucleus

31033:LOC101076896
gene id: 31033:LOC101076896
uniprot id: H2TN23
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

31033:LOC101079428
gene id: 31033:LOC101079428
uniprot id: H2SHR7
names: Subcellular Location Annotation
messages: Mitochondrion matrix

31033:dstn
gene id: 31033:dstn
uniprot id: A0A3B5KBU5
names: Similarity
messages: Belongs to the actin-binding proteins ADF family.

31033:LOC101079855
gene id: 31033:LOC101079855
uniprot id: A0A674MQR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

31033:slc16a1
gene id: 31033:slc16a1
uniprot id: H2VBY9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.
messages: Cell membrane
messages: Membrane
messages: Proton-coupled monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate. Depending on the tissue and on cicumstances, mediates the import or export of lactic acid and ketone bodies. Required for normal nutrient assimilation, increase of white adipose tissue and body weight gain when on a high-fat diet. Plays a role in cellular responses to a high-fat diet by modulating the cellular levels of lactate and pyruvate, small molecules that contribute to the regulation of central metabolic pathways and insulin secretion, with concomitant effects on plasma insulin levels and blood glucose homeostasis.

31033:srsf5
gene id: 31033:srsf5
uniprot id: H2TQY8
names: Similarity
messages: Belongs to the splicing factor SR family.

31033:LOC101066451
gene id: 31033:LOC101066451
uniprot id: H2U5U9
names: Subunit
messages: Homodimer.

31033:cct5
gene id: 31033:cct5
uniprot id: H2TF92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm

31033:prlr
gene id: 31033:prlr
uniprot id: Q1HAY8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type I cytokine receptor family. Type 1 subfamily.
messages: Membrane
messages: The WSXWS motif appears to be necessary for proper protein folding and thereby efficient intracellular transport and cell-surface receptor binding.
messages: The box 1 motif is required for JAK interaction and/or activation.
messages: This is a receptor for the anterior pituitary hormone prolactin.

31033:lep
gene id: 31033:lep
uniprot id: Q588G0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Tissue Specificity
messages: Belongs to the leptin family.
messages: Expressed mostly in the liver.
messages: May function as part of a signaling pathway that acts to regulate the size of the body fat depot.
messages: Secreted

31033:c1qbp
gene id: 31033:c1qbp
uniprot id: A0A674PBX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAM33 family.
messages: Cell membrane

31033:dct
gene id: 31033:dct
uniprot id: Q8QGN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tyrosinase family.
messages: Melanosome membrane

31033:il10
gene id: 31033:il10
uniprot id: Q802T4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-10 family.
messages: Immune regulatory cytokine.
messages: Secreted

31033:fgf7
gene id: 31033:fgf7
uniprot id: A0A3B5KVZ3
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

31033:LOC105417749
gene id: 31033:LOC105417749
uniprot id: H2UD64
names: Similarity
messages: Belongs to the ARTD/PARP family.

31033:hoxa1
gene id: 31033:hoxa1
uniprot id: Q1KL10
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family. Labial subfamily.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

31033:septin6
gene id: 31033:septin6
uniprot id: A0A674MNT4
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.

31033:LOC101072140
gene id: 31033:LOC101072140
uniprot id: A0A674PH95
names: Similarity
messages: Belongs to the protein kinase superfamily.

31033:LOC101075744
gene id: 31033:LOC101075744
uniprot id: H2SNG9
names: Similarity
messages: Belongs to the TMEM14 family.

31033:hebp1
gene id: 31033:hebp1
uniprot id: H2SQV5
names: Similarity
messages: Belongs to the HEBP family.

31033:ormdl1
gene id: 31033:ormdl1
uniprot id: A0A674PJL5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ORM family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Negative regulator of sphingolipid synthesis.

31033:LOC101078425
gene id: 31033:LOC101078425
uniprot id: A0A3B5K976
names: Subcellular Location Annotation
messages: Membrane

31033:rtel1
gene id: 31033:rtel1
uniprot id: H2TJI5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: ATP-dependent DNA helicase implicated in telomere-length regulation, DNA repair and the maintenance of genomic stability. Acts as an anti-recombinase to counteract toxic recombination and limit crossover during meiosis. Regulates meiotic recombination and crossover homeostasis by physically dissociating strand invasion events and thereby promotes noncrossover repair by meiotic synthesis dependent strand annealing (SDSA) as well as disassembly of D loop recombination intermediates. Also disassembles T loops and prevents telomere fragility by counteracting telomeric G4-DNA structures, which together ensure the dynamics and stability of the telomere.
messages: Belongs to the helicase family. RAD3/XPD subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

31033:hoxc12
gene id: 31033:hoxc12
uniprot id: Q1KKV3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

31033:ssr3
gene id: 31033:ssr3
uniprot id: A0A674P9Q8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP-gamma family.
messages: Endoplasmic reticulum membrane
messages: Heterotetramer of TRAP-alpha, TRAP-beta, TRAP-delta and TRAP-gamma.
messages: Membrane
messages: TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins.

31033:homer1
gene id: 31033:homer1
uniprot id: A0A674MCP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Homer family.
messages: Cytoplasm
messages: Postsynaptic density
messages: Synapse

31033:LOC101066792
gene id: 31033:LOC101066792
uniprot id: H2TNW0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the APP family.
messages: Cell membrane
messages: Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

31033:bet1l
gene id: 31033:bet1l
uniprot id: A0A674PLV0
names: Subcellular Location Annotation
messages: Membrane

31033:dipk1a
gene id: 31033:dipk1a
uniprot id: H2SIQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DIPK family.
messages: Endoplasmic reticulum membrane

31033:LOC101073900
gene id: 31033:LOC101073900
uniprot id: H2UKM6
names: Subcellular Location Annotation
messages: Membrane

31033:mrps33
gene id: 31033:mrps33
uniprot id: A0A674PK58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mS33 family.
messages: Mitochondrion

31033:atp5po
gene id: 31033:atp5po
uniprot id: A0A674N7X8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements.
messages: Mitochondrion inner membrane

31033:LOC101073004
gene id: 31033:LOC101073004
uniprot id: A0A674P7V5
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

31033:fam20c4
gene id: 31033:fam20c4
uniprot id: H2S6R4
names: Similarity
messages: Belongs to the FAM20 family.

31033:mindy2
gene id: 31033:mindy2
uniprot id: H2V8P1
names: Function
names: Similarity
messages: Belongs to the MINDY deubiquitinase family. FAM63 subfamily.
messages: Hydrolase that can specifically remove 'Lys-48'-linked conjugated ubiquitin from proteins. Has exodeubiquitinase activity and has a preference for long polyubiquitin chains. May play a regulatory role at the level of protein turnover.

31033:LOC101073552
gene id: 31033:LOC101073552
uniprot id: A0A674MUE7
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

31033:slc35b2
gene id: 31033:slc35b2
uniprot id: A0A674NI59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide-sugar transporter family. SLC35B subfamily.
messages: Membrane

31033:LOC101072793
gene id: 31033:LOC101072793
uniprot id: H2U140
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

31033:LOC101062326
gene id: 31033:LOC101062326
uniprot id: H2TKG0
names: Similarity
messages: Belongs to the KHDRBS family.

31033:elp4
gene id: 31033:elp4
uniprot id: H2SZ22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELP4 family.
messages: Cytoplasm
messages: Nucleus

31033:LOC101072362
gene id: 31033:LOC101072362
uniprot id: H2UM37
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

31033:kars
gene id: 31033:kars
uniprot id: H2V6Z7
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

31033:LOC101068811
gene id: 31033:LOC101068811
uniprot id: A0A3B5K7W8
names: Similarity
messages: Belongs to the nanos family.

31033:crabp1
gene id: 31033:crabp1
uniprot id: A0A674NA52
names: Function
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
messages: Cytosolic CRABPs may regulate the access of retinoic acid to the nuclear retinoic acid receptors.

31033:LOC101079880
gene id: 31033:LOC101079880
uniprot id: A0A3B5KMF9
names: Caution
names: Similarity
messages: Belongs to the LDLR family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

31033:LOC101079677
gene id: 31033:LOC101079677
uniprot id: H2TWA3
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.

31033:LOC101063840
gene id: 31033:LOC101063840
uniprot id: A0A3B5KH35
names: Similarity
messages: Belongs to the MS4A family.

31033:dnm3
gene id: 31033:dnm3
uniprot id: H2UYQ5
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.

31033:LOC101069359
gene id: 31033:LOC101069359
uniprot id: H2UL75
names: Function
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
messages: Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues within the same substrate, with a preference for phosphotyrosine as a substrate (By similarity). Involved in the modulation of AMPK and MAPK1/2 signaling pathways.
messages: Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate.

31033:capn15
gene id: 31033:capn15
uniprot id: A0A3B5KLM3
uniprot id: H2UHV7
names: Similarity
messages: Belongs to the peptidase C2 family.

31033:LOC101077937
gene id: 31033:LOC101077937
uniprot id: H2V2P9
names: Subcellular Location Annotation
messages: Membrane
messages: dendrite

31033:elf3
gene id: 31033:elf3
uniprot id: A0A3B5KA01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

31033:LOC101064814
gene id: 31033:LOC101064814
uniprot id: A0A674MS57
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.
messages: Membrane

31033:LOC101073846
gene id: 31033:LOC101073846
uniprot id: A0A3B5KN95
names: Similarity
messages: Belongs to the yippee family.

31033:pusl1
gene id: 31033:pusl1
uniprot id: H2TL91
names: Similarity
messages: Belongs to the tRNA pseudouridine synthase TruA family.

31033:LOC101076743
gene id: 31033:LOC101076743
uniprot id: H2TMA8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family.
messages: Catalyzes the synthesis of phosphoribosylpyrophosphate (PRPP) that is essential for nucleotide synthesis.
messages: Homodimer. The active form is probably a hexamer composed of 3 homodimers.

31033:vps18
gene id: 31033:vps18
uniprot id: H2U883
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS18 family.
messages: Membrane

31033:LOC101075392
gene id: 31033:LOC101075392
uniprot id: A0A3B5K5Y2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

31033:inpp5d
gene id: 31033:inpp5d
uniprot id: H2RSB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inositol 1,4,5-trisphosphate 5-phosphatase family.
messages: Membrane

31033:LOC101064065
gene id: 31033:LOC101064065
uniprot id: H2SQL1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS37 family.
messages: Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in cell growth and differentiation.
messages: Endosome membrane
messages: Late endosome membrane

31033:LOC101071192
gene id: 31033:LOC101071192
uniprot id: H2TMK3
names: Subcellular Location Annotation
messages: Nucleus

31033:sumo1
gene id: 31033:sumo1
uniprot id: A0A674MKB3
uniprot id: A0A674MY12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ubiquitin family. SUMO subfamily.
messages: Nucleus

31033:LOC101061775
gene id: 31033:LOC101061775
uniprot id: A0A3B5K482
names: Function
names: Similarity
messages: Belongs to the vestigial family.
messages: May act as a specific coactivator for the mammalian TEFs.

31033:rhbg
gene id: 31033:rhbg
uniprot id: Q18PF6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Tissue Specificity
messages: Apicolateral cell membrane
messages: Belongs to the ammonium transporter (TC 2.A.49) family. Rh subfamily.
messages: Cytoplasmic vesicle membrane
messages: Functions as an ammonia transporter. May play a role in the elimination of ammonia in the gill.
messages: Specifically expressed in the gill by pavement cells (at protein level).

31033:LOC101065425
gene id: 31033:LOC101065425
uniprot id: A0A3B5K588
names: Similarity
messages: Belongs to the small GTPase superfamily. Ras family.

31033:tpm1-2
gene id: 31033:tpm1-2
uniprot id: Q805C9
uniprot id: Q805D0
uniprot id: Q8JIM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tropomyosin family.
messages: cytoskeleton

31033:LOC101071886
gene id: 31033:LOC101071886
uniprot id: H2UXD9
names: Similarity
messages: Belongs to the glycosyl hydrolase 56 family.

31033:ctbs
gene id: 31033:ctbs
uniprot id: H2V6F7
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family.

31033:serinc5
gene id: 31033:serinc5
uniprot id: H2TJX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TDE1 family.
messages: Cell membrane
messages: Membrane

31033:nbl1
gene id: 31033:nbl1
uniprot id: H2TK82
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DAN family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

31033:LOC101080028
gene id: 31033:LOC101080028
uniprot id: A0A3B5K8T7
names: Similarity
messages: Belongs to the MAGUK family.

31033:plcb4
gene id: 31033:plcb4
uniprot id: H2TF26
names: Function
messages: The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.

31033:LOC105416774
gene id: 31033:LOC105416774
uniprot id: H2TUI7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

31033:sox8
gene id: 31033:sox8
uniprot id: Q5BM60
names: Subcellular Location Annotation
messages: Nucleus

31033:vps51
gene id: 31033:vps51
uniprot id: A0A674MM01
uniprot id: H2RQV0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the VPS51 family.
messages: Component of the Golgi-associated retrograde protein (GARP) complex. Component of the endosome-associated retrograde protein (EARP) complex.
messages: Endosome
messages: Involved in retrograde transport from early and late endosomes to the late Golgi. The GARP complex is required for the maintenance of protein retrieval from endosomes to the TGN, acid hydrolase sorting, lysosome function, endosomal cholesterol traffic and autophagy. Acts as component of the EARP complex that is involved in endocytic recycling.
messages: Recycling endosome
messages: trans-Golgi network

31033:rell1
gene id: 31033:rell1
uniprot id: A0A3B5KLL4
names: Similarity
messages: Belongs to the RELT family.

31033:mapk10
gene id: 31033:mapk10
uniprot id: A0A674MHI0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.
messages: Cytoplasm
messages: Responds to activation by environmental stress and pro-inflammatory cytokines by phosphorylating a number of transcription factors, and thus regulates transcriptional activity.

31033:LOC101061990
gene id: 31033:LOC101061990
uniprot id: A0A3B5KH47
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.

31033:tpst1
gene id: 31033:tpst1
uniprot id: H2U9A8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein sulfotransferase family.
messages: Catalyzes the O-sulfation of tyrosine residues within acidic motifs of polypeptides, using 3'-phosphoadenylyl sulfate (PAPS) as cosubstrate.
messages: Golgi apparatus membrane

31033:LOC105417801
gene id: 31033:LOC105417801
uniprot id: A0A3B5KAC2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

31033:tsnax
gene id: 31033:tsnax
uniprot id: Q8AUM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the translin family.
messages: Nucleus

31033:gcg
gene id: 31033:gcg
uniprot id: H2SF28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glucagon family.
messages: Secreted

31033:opn3
gene id: 31033:opn3
uniprot id: H2TX79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
messages: Membrane

31033:LOC101063381
gene id: 31033:LOC101063381
uniprot id: H2TX50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Cytoplasm
messages: Nucleus

31033:LOC101077988
gene id: 31033:LOC101077988
uniprot id: H2S845
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. This subunit is involved in antigen processing to generate class I binding peptides.

31033:lrrn3
gene id: 31033:lrrn3
uniprot id: H2SKI5
names: Subcellular Location Annotation
messages: Membrane

31033:LOC101072587
gene id: 31033:LOC101072587
uniprot id: H2V162
names: Similarity
messages: Belongs to the cyclin family. Cyclin AB subfamily.

31033:KEF89 p03
gene id: 31033:KEF89_p03
uniprot id: Q8HCV5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 5 family.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.
messages: Membrane
messages: Mitochondrion inner membrane

31033:serpine2
gene id: 31033:serpine2
uniprot id: H2TQ93
names: Similarity
messages: Belongs to the serpin family.

31033:dbnl
gene id: 31033:dbnl
uniprot id: A0A674M8V7
uniprot id: A0A674P8N3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABP1 family.
messages: Cell membrane
messages: Early endosome
messages: Endosome
messages: Golgi apparatus membrane
messages: Perikaryon
messages: Postsynaptic density
messages: Synapse
messages: cell cortex
messages: clathrin-coated vesicle membrane
messages: cytoskeleton
messages: dendrite
messages: lamellipodium
messages: neuron projection
messages: podosome
messages: ruffle

31033:ttc36
gene id: 31033:ttc36
uniprot id: A0A3B5KWH6
names: Similarity
messages: Belongs to the TTC36 family.

31033:tacr2
gene id: 31033:tacr2
uniprot id: H2S9N1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

31033:LOC101076451
gene id: 31033:LOC101076451
uniprot id: H2RQA0
names: Similarity
messages: Belongs to the WD repeat CDC20/Fizzy family.

31033:LOC101079120
gene id: 31033:LOC101079120
uniprot id: A0A3B5KRU7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

31033:asip
gene id: 31033:asip
uniprot id: A0ZSG4
names: Subcellular Location Annotation
messages: Secreted

31033:LOC101065179
gene id: 31033:LOC101065179
uniprot id: A0A674NZT8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/MEIS homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

31033:LOC101069419
gene id: 31033:LOC101069419
uniprot id: H2TA75
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELO family. ELOVL6 subfamily.
messages: Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that elongates fatty acids with 12, 14 and 16 carbons with higher activity toward C16:0 acyl-CoAs. Catalyzes the synthesis of unsaturated C16 long chain fatty acids and, to a lesser extent, C18:0 and those with low desaturation degree. May participate to the production of saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: N-Glycosylated.

31033:LOC101061545
gene id: 31033:LOC101061545
uniprot id: A0A674MML4
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

31033:LOC101074699
gene id: 31033:LOC101074699
uniprot id: H2TVT1
names: Similarity
messages: Belongs to the epsin family.

31033:hpse
gene id: 31033:hpse
uniprot id: H2VEW5
names: Similarity
messages: Belongs to the glycosyl hydrolase 79 family.

31033:creb3l4
gene id: 31033:creb3l4
uniprot id: H2TTJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. ATF subfamily.
messages: Endoplasmic reticulum membrane
messages: Membrane

31033:pfdn2
gene id: 31033:pfdn2
uniprot id: H2SE99
names: Function
names: Similarity
messages: Belongs to the prefoldin subunit beta family.
messages: Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.

31033:ndufa1
gene id: 31033:ndufa1
uniprot id: H2TQ99
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA1 subunit family.
messages: Mitochondrion inner membrane

31033:LOC101074525
gene id: 31033:LOC101074525
uniprot id: A0A674PFG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic cobalamin transport proteins family.
messages: Secreted

31033:LOC101080225
gene id: 31033:LOC101080225
uniprot id: H2TZM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

31033:LOC101068908
gene id: 31033:LOC101068908
uniprot id: H2UEB2
names: Similarity
messages: Belongs to the TTC39 family.

31033:actn4
gene id: 31033:actn4
uniprot id: A0A674PQ94
names: Similarity
messages: Belongs to the alpha-actinin family.

31033:fam155a
gene id: 31033:fam155a
uniprot id: H2SM68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NALF family.
messages: Membrane

31033:ldlr
gene id: 31033:ldlr
uniprot id: A0A7G7XWQ0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

31033:dock8
gene id: 31033:dock8
uniprot id: A0A674MD03
names: Similarity
messages: Belongs to the DOCK family.

31033:LOC101075591
gene id: 31033:LOC101075591
uniprot id: H2UD84
names: Function
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family.
messages: Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis.

31033:LOC101076120
gene id: 31033:LOC101076120
uniprot id: H2U4R3
names: Similarity
messages: Belongs to the cytochrome P450 family.

31033:chst14
gene id: 31033:chst14
uniprot id: H2UT52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 2 family.
messages: Golgi apparatus membrane
messages: Membrane

31033:rab9a
gene id: 31033:rab9a
uniprot id: H2TAZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: phagosome membrane

31033:LOC101075886
gene id: 31033:LOC101075886
uniprot id: H2RSD9
names: Similarity
messages: Belongs to the cytochrome P450 family.

31033:ctsd
gene id: 31033:ctsd
uniprot id: Q5TLU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A1 family.
messages: Lysosome

31033:npepl1
gene id: 31033:npepl1
uniprot id: A0A674NA39
names: Similarity
messages: Belongs to the peptidase M17 family.

31033:ppp5c
gene id: 31033:ppp5c
uniprot id: A0A3B5JXP2
names: Similarity
messages: Belongs to the PPP phosphatase family. PP-5 (PP-T) subfamily.

31033:septin10
gene id: 31033:septin10
uniprot id: A0A674NLV8
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.

31033:LOC101077566
gene id: 31033:LOC101077566
uniprot id: H2S7D0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PGAP2 family.
messages: Involved in the lipid remodeling steps of GPI-anchor maturation. Required for stable expression of GPI-anchored proteins at the cell surface.
messages: Membrane

31033:LOC101077726
gene id: 31033:LOC101077726
uniprot id: H2V187
names: Similarity
messages: Belongs to the peptidase C2 family.

31033:serpini1
gene id: 31033:serpini1
uniprot id: H2U3L2
names: Similarity
messages: Belongs to the serpin family.

31033:ptgir
gene id: 31033:ptgir
uniprot id: H2TY14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

31033:trpv4
gene id: 31033:trpv4
uniprot id: A0A674PP79
names: Subcellular Location Annotation
messages: Membrane

31033:LOC101072487
gene id: 31033:LOC101072487
uniprot id: H2V2G4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

31033:tfap2a
gene id: 31033:tfap2a
uniprot id: A0A674MED6
uniprot id: A0A674P0A4
uniprot id: H2SNY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AP-2 family.
messages: Nucleus

31033:LOC101067448
gene id: 31033:LOC101067448
uniprot id: H2TT57
names: Similarity
names: Subunit
messages: Belongs to the 14-3-3 family.
messages: Homodimer, and heterodimer with other family members.

31033:LOC777976
gene id: 31033:LOC777976
uniprot id: Q2NNA7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the noggin family.
messages: Homodimer.
messages: Secreted

31033:LOC101062856
gene id: 31033:LOC101062856
uniprot id: H2T8F9
names: Similarity
messages: Belongs to the heat shock protein 70 family.

31033:trmt5
gene id: 31033:trmt5
uniprot id: H2TS57
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRM5 / TYW2 family.
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM5/TYW2 family.
messages: Cytoplasm
messages: Mitochondrion matrix
messages: Monomer.
messages: Nucleus
messages: Specifically methylates the N1 position of guanosine-37 in various cytoplasmic and mitochondrial tRNAs. Methylation is not dependent on the nature of the nucleoside 5' of the target nucleoside. This is the first step in the biosynthesis of wybutosine (yW), a modified base adjacent to the anticodon of tRNAs and required for accurate decoding.

31033:tas1r1
gene id: 31033:tas1r1
uniprot id: Q2MHK0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

31033:LOC105417094
gene id: 31033:LOC105417094
uniprot id: A0A3B5KJT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IRF2BP family.
messages: Nucleus

31033:ccnb3
gene id: 31033:ccnb3
uniprot id: H2SMD5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cyclin family. Cyclin AB subfamily.
messages: Essential for the control of the cell cycle at the G2/M (mitosis) transition.
messages: Interacts with the CDK1 protein kinase to form a serine/threonine kinase holoenzyme complex also known as maturation promoting factor (MPF). The cyclin subunit imparts substrate specificity to the complex.

31033:hars
gene id: 31033:hars
uniprot id: A0A3F2YPF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm

31033:c7h8orf37
gene id: 31033:c7h8orf37
uniprot id: A0A674MUI6
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: May be involved in photoreceptor outer segment disk morphogenesis.
messages: Photoreceptor inner segment

31033:melk
gene id: 31033:melk
uniprot id: H2SD98
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.

31033:dpm1
gene id: 31033:dpm1
uniprot id: A0A3B5KV61
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycosyltransferase 2 family.
messages: Component of the dolichol-phosphate mannose (DPM) synthase complex.
messages: Endoplasmic reticulum
messages: Transfers mannose from GDP-mannose to dolichol monophosphate to form dolichol phosphate mannose (Dol-P-Man) which is the mannosyl donor in pathways leading to N-glycosylation, glycosyl phosphatidylinositol membrane anchoring, and O-mannosylation of proteins; catalytic subunit of the dolichol-phosphate mannose (DPM) synthase complex.

31033:b3gat3
gene id: 31033:b3gat3
uniprot id: H2SIS1
uniprot id: Q5CB05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 43 family.
messages: Golgi apparatus membrane
messages: Membrane

31033:wnt6
gene id: 31033:wnt6
uniprot id: A0A3B5JZP1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

31033:itgb8
gene id: 31033:itgb8
uniprot id: H2T4I5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin beta chain family.
messages: Membrane

31033:LOC101073896
gene id: 31033:LOC101073896
uniprot id: H2SEE0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for thyrotropin-releasing hormone (TRH). Upon ligand binding, this G-protein-coupled receptor triggers activation of the phosphatidylinositol (IP3)-calcium-protein kinase C (PKC) pathway.

31033:timp-2b
gene id: 31033:timp-2b
uniprot id: Q4JF89
names: Similarity
messages: Belongs to the protease inhibitor I35 (TIMP) family.

31033:LOC101079249
gene id: 31033:LOC101079249
uniprot id: A0A674MD34
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family. PDE4 subfamily.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

31033:zeb2
gene id: 31033:zeb2
uniprot id: H2SIJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the delta-EF1/ZFH-1 C2H2-type zinc-finger family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

31033:LOC101073735
gene id: 31033:LOC101073735
uniprot id: H2UIK7
uniprot id: H2UIK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MYST (SAS/MOZ) family.
messages: Nucleus

31033:ezh1
gene id: 31033:ezh1
uniprot id: H2UN44
names: Subcellular Location Annotation
messages: Nucleus

31033:nudc
gene id: 31033:nudc
uniprot id: H2U0J5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nudC family.
messages: Midbody
messages: spindle

31033:cxcr4
gene id: 31033:cxcr4
uniprot id: H2TD98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Early endosome
messages: Endosome
messages: Membrane

31033:ren
gene id: 31033:ren
uniprot id: Q6IMP1
names: Similarity
messages: Belongs to the peptidase A1 family.

31033:LOC101065234
gene id: 31033:LOC101065234
uniprot id: H2THC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
messages: Cytoplasm
messages: Membrane

31033:LOC101074215
gene id: 31033:LOC101074215
uniprot id: H2SW69
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

31033:ttll1
gene id: 31033:ttll1
uniprot id: H2U4M9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tubulin polyglutamylase family.
messages: cilium basal body

31033:nt5c3a
gene id: 31033:nt5c3a
uniprot id: A0A674N3B0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrimidine 5'-nucleotidase family.
messages: Cytoplasm

31033:phlda2
gene id: 31033:phlda2
uniprot id: H2TC08
names: Subcellular Location Annotation
messages: Cytoplasm

31033:LOC101072932
gene id: 31033:LOC101072932
uniprot id: H2V020
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

31033:LOC101073734
gene id: 31033:LOC101073734
uniprot id: H2TAG5
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. RAC subfamily.

31033:lztfl1
gene id: 31033:lztfl1
uniprot id: H2T1G8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LZTFL1 family.
messages: Cytoplasm
messages: Regulates ciliary localization of the BBSome complex. Together with the BBSome complex, controls SMO ciliary trafficking and contributes to the sonic hedgehog (SHH) pathway regulation. May play a role in neurite outgrowth. May have tumor suppressor function.
messages: Self-associates. Interacts with BBS9; the interaction mediates the association of LZTL1 with the BBsome complex and regulates BBSome ciliary trafficking.

31033:KEF89 p13
gene id: 31033:KEF89_p13
uniprot id: Q8HCW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 1 family.
messages: Membrane
messages: Mitochondrion inner membrane

31033:hmox2
gene id: 31033:hmox2
uniprot id: H2SXN5
names: Similarity
messages: Belongs to the heme oxygenase family.

31033:opa3
gene id: 31033:opa3
uniprot id: H2UP11
names: Function
names: Similarity
messages: Belongs to the OPA3 family.
messages: May play some role in mitochondrial processes.

31033:LOC101061436
gene id: 31033:LOC101061436
uniprot id: H2SEU8
names: Similarity
messages: Belongs to the cytochrome P450 family.

31033:cab39
gene id: 31033:cab39
uniprot id: H2STL7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mo25 family.
messages: Component of a complex that binds and activates STK11/LKB1. In the complex, required to stabilize the interaction between CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta) and STK11/LKB1.
messages: Component of a trimeric complex composed of STK11/LKB1, STRAD (STRADA or STRADB) and CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta): the complex tethers STK11/LKB1 in the cytoplasm and stimulates its catalytic activity.

31033:slc10a7
gene id: 31033:slc10a7
uniprot id: H2V6L0
uniprot id: H2V6L1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bile acid:sodium symporter (BASS) (TC 2.A.28) family.
messages: Cell membrane
messages: Does not show transport activity towards bile acids or steroid sulfates.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane

31033:cldn5b
gene id: 31033:cldn5b
uniprot id: Q6E5S6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

31033:LOC101068594
gene id: 31033:LOC101068594
uniprot id: A0A6I8PS55
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: GTP-binding protein involved in protein trafficking; modulates vesicle budding and uncoating within the Golgi apparatus.
messages: Golgi apparatus

31033:cers1
gene id: 31033:cers1
uniprot id: H2TYB5
names: Subcellular Location Annotation
messages: Membrane

31033:LOC101071071
gene id: 31033:LOC101071071
uniprot id: A0A674NRX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Membrane

31033:p2rx5
gene id: 31033:p2rx5
uniprot id: H2RPY1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the P2X receptor family.
messages: Functional P2XRs are organized as homomeric and heteromeric trimers.
messages: Membrane
messages: Receptor for ATP that acts as a ligand-gated ion channel.

31033:abitram
gene id: 31033:abitram
uniprot id: A0A3B5KB98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABITRAM family.
messages: growth cone
messages: lamellipodium

31033:mtx2
gene id: 31033:mtx2
uniprot id: Q1KKR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metaxin family.
messages: Membrane
messages: Mitochondrion outer membrane

31033:LOC101076843
gene id: 31033:LOC101076843
uniprot id: Q800B0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. Jun subfamily.
messages: Nucleus

31033:LOC105417514
gene id: 31033:LOC105417514
uniprot id: A0A3B5KH97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endothelin/sarafotoxin family.
messages: Secreted

31033:zfhx4
gene id: 31033:zfhx4
uniprot id: H2RJP5
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

31033:zmpste24
gene id: 31033:zmpste24
uniprot id: H2T8A5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48A family.
messages: Binds 1 zinc ion per subunit.
messages: Endoplasmic reticulum membrane
messages: Proteolytically removes the C-terminal three residues of farnesylated proteins.

31033:LOC101076719
gene id: 31033:LOC101076719
uniprot id: A0A674PN53
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ephrin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

31033:atp5mf
gene id: 31033:atp5mf
uniprot id: H2S6Q4
names: Function
names: Similarity
messages: Belongs to the ATPase F chain family.
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. Minor subunit located with subunit a in the membrane.

31033:LOC101073700
gene id: 31033:LOC101073700
uniprot id: A0A3B5KPM5
names: Subcellular Location Annotation
messages: cytoskeleton

31033:ctu1
gene id: 31033:ctu1
uniprot id: H2UWQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TtcA family. CTU1/NCS6/ATPBD3 subfamily.
messages: Cytoplasm
messages: Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position.

31033:LOC101069389
gene id: 31033:LOC101069389
uniprot id: A0A3B5KI94
uniprot id: H2S547
names: Similarity
messages: Belongs to the ribose-phosphate pyrophosphokinase family.

31033:LOC101062302
gene id: 31033:LOC101062302
uniprot id: H2T4G9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.

31033:gpr161
gene id: 31033:gpr161
uniprot id: A0A3B5K5C1
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

31033:c22h5orf22
gene id: 31033:c22h5orf22
uniprot id: H2U311
names: Similarity
messages: Belongs to the UPF0489 family.

31033:LOC101067383
gene id: 31033:LOC101067383
uniprot id: H2THA7
names: Similarity
messages: Belongs to the SNF7 family.

31033:LOC101068977
gene id: 31033:LOC101068977
uniprot id: H2RN76
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CUT homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

31033:LOC101064174
gene id: 31033:LOC101064174
uniprot id: A0A3B5K053
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

31033:itgb4
gene id: 31033:itgb4
uniprot id: H2SP20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin beta chain family.
messages: Membrane

31033:LOC101072717
gene id: 31033:LOC101072717
uniprot id: A0A674MSJ9
names: Similarity
messages: Belongs to the cytochrome c oxidase VIIa family.

31033:tnfsf10
gene id: 31033:tnfsf10
uniprot id: F8RC19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tumor necrosis factor family.
messages: Membrane
messages: Secreted

31033:mkx
gene id: 31033:mkx
uniprot id: A0A674NWQ3
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

31033:sdhaf4
gene id: 31033:sdhaf4
uniprot id: A0A674NLQ7
names: Similarity
messages: Belongs to the SDHAF4 family.

31033:cldn34
gene id: 31033:cldn34
uniprot id: Q6E5P4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: tight junction

31033:LOC105417715
gene id: 31033:LOC105417715
uniprot id: H2RUY8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H4 family.
messages: Chromosome
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

31033:LOC446041
gene id: 31033:LOC446041
uniprot id: Q6SYV3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts specifically as a negative regulator of skeletal muscle growth.
messages: Belongs to the TGF-beta family.
messages: Homodimer; disulfide-linked.
messages: Secreted

31033:LOC101069808
gene id: 31033:LOC101069808
uniprot id: H2SYN5
names: Similarity
messages: Belongs to the ataxin-2 family.

31033:mrps15
gene id: 31033:mrps15
uniprot id: H2TTT0
names: Similarity
messages: Belongs to the universal ribosomal protein uS15 family.

31033:kcnc4
gene id: 31033:kcnc4
uniprot id: H2S8X6
names: Subcellular Location Annotation
messages: Membrane

31033:nosip
gene id: 31033:nosip
uniprot id: H2TIP4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOSIP family.
messages: Cytoplasm
messages: Negatively regulates nitric oxide production by inducing nitric oxide synthase translocation to actin cytoskeleton and inhibiting its enzymatic activity.
messages: Nucleus

31033:slc12a6
gene id: 31033:slc12a6
uniprot id: H2S542
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC12A transporter family.
messages: Membrane

31033:rab3ip
gene id: 31033:rab3ip
uniprot id: H2SYK3
names: Similarity
messages: Belongs to the SEC2 family.

31033:LOC101069671
gene id: 31033:LOC101069671
uniprot id: H2UX64
names: Similarity
messages: Belongs to the CDI family.

31033:bbs4
gene id: 31033:bbs4
uniprot id: H2UZ90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BBS4 family.
messages: Membrane
messages: centrosome
messages: cilium membrane

31033:dnajc22
gene id: 31033:dnajc22
uniprot id: H2U0K7
names: Function
names: Subcellular Location Annotation
messages: May function as a co-chaperone.
messages: Membrane

31033:jph3
gene id: 31033:jph3
uniprot id: A0A674MIG9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the junctophilin family.
messages: Cell membrane
messages: Endoplasmic reticulum membrane
messages: Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels.
messages: Membrane

31033:syngr3
gene id: 31033:syngr3
uniprot id: H2RVU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptogyrin family.
messages: Membrane

31033:rag1
gene id: 31033:rag1
uniprot id: Q9W699
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RAG1 family.
messages: Binds 1 divalent metal cation per subunit. Mg(2+) or Mn(2+).
messages: Catalytic component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T-lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. In the RAG complex, RAG1 mediates the DNA-binding to the conserved recombination signal sequences (RSS) and catalyzes the DNA cleavage activities by introducing a double-strand break between the RSS and the adjacent coding segment. RAG2 is not a catalytic component but is required for all known catalytic activities. DNA cleavage occurs in 2 steps: a first nick is introduced in the top strand immediately upstream of the heptamer, generating a 3'-hydroxyl group that can attack the phosphodiester bond on the opposite strand in a direct transesterification reaction, thereby creating 4 DNA ends: 2 hairpin coding ends and 2 blunt, 5'-phosphorylated ends.
messages: Homodimer.
messages: Nucleus
messages: The NBD (nonamer binding) DNA-binding domain mediates the specific binding to the nonamer RSS motif by forming a tightly interwoven homodimer that binds and synapses 2 nonamer elements, with each NBD making contact with both DNA molecules. Each RSS is composed of well-conserved heptamer (consensus 5'-CACAGTG-3') and nonamer (consensus 5'-ACAAAAACC-3') sequences separated by a spacer of either 12 bp or 23 bp.

31033:LOC101076576
gene id: 31033:LOC101076576
uniprot id: H2URZ6
names: Subcellular Location Annotation
messages: Nucleus

31033:mlf2
gene id: 31033:mlf2
uniprot id: H2T949
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MLF family.
messages: Cytoplasm

31033:banf1
gene id: 31033:banf1
uniprot id: A0A674P9V4
names: Subcellular Location Annotation
messages: Nucleus

31033:tsnare1
gene id: 31033:tsnare1
uniprot id: H2UWA7
names: Similarity
messages: Belongs to the syntaxin family.

31033:LOC101067574
gene id: 31033:LOC101067574
uniprot id: H2UZ46
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

31033:LOC101077745
gene id: 31033:LOC101077745
uniprot id: H2RZ53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the E2F/DP family.
messages: Nucleus

31033:LOC101072115
gene id: 31033:LOC101072115
uniprot id: A0A674P0E6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

31033:nup85
gene id: 31033:nup85
uniprot id: H2TUD8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nucleoporin Nup85 family.
messages: Component of the nuclear pore complex (NPC).
messages: Functions as a component of the nuclear pore complex (NPC).
messages: Nucleus membrane
messages: nuclear pore complex

31033:LOC101065972
gene id: 31033:LOC101065972
uniprot id: A0A3B5KBY7
names: Function
names: Similarity
messages: Belongs to the NifU family.
messages: Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins.

31033:vsx2
gene id: 31033:vsx2
uniprot id: A0A674NG98
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

31033:nlgn1
gene id: 31033:nlgn1
uniprot id: D2X2G6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type-B carboxylesterase/lipase family.
messages: Cell membrane
messages: Membrane

31033:LOC101077877
gene id: 31033:LOC101077877
uniprot id: A0A3B5JZY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM88 family.
messages: Membrane

31033:LOC101078653
gene id: 31033:LOC101078653
uniprot id: A0A674P681
names: Similarity
names: Subunit
messages: Belongs to the 14-3-3 family.
messages: Homodimer, and heterodimer with other family members.

31033:cpm
gene id: 31033:cpm
uniprot id: A0A674NJ51
names: Similarity
messages: Belongs to the peptidase M14 family.

31033:LOC101061299
gene id: 31033:LOC101061299
uniprot id: A0A674P7W3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM163 family.
messages: Membrane

31033:LOC101062617
gene id: 31033:LOC101062617
uniprot id: H2SWW8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NECAP family.
messages: Involved in endocytosis.
messages: clathrin-coated vesicle membrane

31033:LOC101069640
gene id: 31033:LOC101069640
uniprot id: H2RQ44
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

31033:LOC101066662
gene id: 31033:LOC101066662
uniprot id: A0A674P199
names: Subcellular Location Annotation
messages: Nucleus

31033:egr3
gene id: 31033:egr3
uniprot id: H2RXQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EGR C2H2-type zinc-finger protein family.
messages: Nucleus

31033:slc26a3
gene id: 31033:slc26a3
uniprot id: A0A674NS55
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Chloride/bicarbonate exchanger.
messages: Membrane

31033:vps45
gene id: 31033:vps45
uniprot id: A0A3B5K622
names: Similarity
messages: Belongs to the STXBP/unc-18/SEC1 family.

31033:fgf3
gene id: 31033:fgf3
uniprot id: A0A674NKG2
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

31033:rpl11
gene id: 31033:rpl11
uniprot id: A0A3B5KKK2
uniprot id: A0A674MUT3
names: Similarity
messages: Belongs to the universal ribosomal protein uL5 family.

31033:gnptab
gene id: 31033:gnptab
uniprot id: H2U168
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the stealth family.
messages: Membrane

31033:gata2
gene id: 31033:gata2
uniprot id: A0A3B5JVZ9
uniprot id: A0A3B5K827
names: Subcellular Location Annotation
messages: Nucleus

31033:LOC777991
gene id: 31033:LOC777991
uniprot id: H2SH46
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

31033:skil
gene id: 31033:skil
uniprot id: H2SJH9
names: Similarity
messages: Belongs to the SKI family.

31033:mrpl15
gene id: 31033:mrpl15
uniprot id: H2T1U6
names: Similarity
messages: Belongs to the universal ribosomal protein uL15 family.

31033:cnnm3
gene id: 31033:cnnm3
uniprot id: A0A097ZIH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ACDP family.
messages: Membrane

31033:cmtm3
gene id: 31033:cmtm3
uniprot id: H2V4Q1
names: Subcellular Location Annotation
messages: Membrane

31033:meis1
gene id: 31033:meis1
uniprot id: A0A674NP53
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/MEIS homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

31033:gas6
gene id: 31033:gas6
uniprot id: H2V4I6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

31033:sgk2
gene id: 31033:sgk2
uniprot id: A0A674MMD6
names: Similarity
messages: Belongs to the protein kinase superfamily.

31033:rpl14
gene id: 31033:rpl14
uniprot id: Q98SE0
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL14 family.

31033:prdm12
gene id: 31033:prdm12
uniprot id: H2VF00
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class V-like SAM-binding methyltransferase superfamily.
messages: Involved in the positive regulation of histone H3-K9 dimethylation.
messages: Nucleus

31033:tmem167a
gene id: 31033:tmem167a
uniprot id: A0A674NN01
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KISH family.
messages: Golgi apparatus membrane
messages: Involved in the early part of the secretory pathway.
messages: Membrane

31033:st8sia5
gene id: 31033:st8sia5
uniprot id: Q6KC01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

31033:LOC446029
gene id: 31033:LOC446029
uniprot id: H2S970
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

31033:LOC101062924
gene id: 31033:LOC101062924
uniprot id: A0A674P3T8
names: Similarity
messages: Belongs to the CD225/Dispanin family.

31033:bmp15
gene id: 31033:bmp15
uniprot id: A0A3B5K3Z6
names: Similarity
messages: Belongs to the TGF-beta family.

31033:orc3
gene id: 31033:orc3
uniprot id: H2SQM4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ORC3 family.
messages: Component of ORC, a complex composed of at least 6 subunits: ORC1, ORC2, ORC3, ORC4, ORC5 and ORC6. ORC is regulated in a cell-cycle dependent manner. It is sequentially assembled at the exit from anaphase of mitosis and disassembled as cells enter S phase.
messages: Nucleus

31033:ranbp10
gene id: 31033:ranbp10
uniprot id: A0A3B5KD73
names: Similarity
messages: Belongs to the RANBP9/10 family.

31033:LOC101079999
gene id: 31033:LOC101079999
uniprot id: H2V0Q1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UDP-glycosyltransferase family.
messages: Membrane

31033:smim8
gene id: 31033:smim8
uniprot id: A0A674NB22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMIM8 family.
messages: Membrane

31033:LOC105416819
gene id: 31033:LOC105416819
uniprot id: A0A3B5JZ60
names: Subcellular Location Annotation
messages: Membrane

31033:LOC101062507
gene id: 31033:LOC101062507
uniprot id: H2S9D3
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.

31033:LOC101068591
gene id: 31033:LOC101068591
uniprot id: A0A3B5KR16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COX15/CtaA family.
messages: Membrane

31033:LOC101062479
gene id: 31033:LOC101062479
uniprot id: A0A3B5KAS1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

31033:p22phox
gene id: 31033:p22phox
uniprot id: Q7T1Q0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the p22phox family.
messages: Cell membrane
messages: Composed of a heavy chain (beta) and a light chain (alpha). Component of an NADPH oxidase complex composed of a heterodimer formed by the membrane proteins CYBA and CYBB and the cytosolic subunits NCF1, NCF2 and NCF4. Interacts with NCF1 (via SH3 domain).
messages: Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. Associates with NOX3 to form a functional NADPH oxidase constitutively generating superoxide.
messages: Membrane

31033:pes1
gene id: 31033:pes1
uniprot id: H2UUQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pescadillo family.
messages: Component of the PeBoW complex, composed of BOP1, PES1 and WDR12. Within the PeBoW complex BOP1 interacts directly with PES1 and WDR12. The PeBoW complex also associates with the 66S pre-ribosome.
messages: Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.
messages: nucleolus
messages: nucleoplasm

31033:atic
gene id: 31033:atic
uniprot id: H2V3V7
names: Similarity
messages: Belongs to the PurH family.

31033:aar2
gene id: 31033:aar2
uniprot id: H2S162
names: Function
names: Similarity
messages: Belongs to the AAR2 family.
messages: Component of the U5 snRNP complex that is required for spliceosome assembly and for pre-mRNA splicing.

31033:naa38
gene id: 31033:naa38
uniprot id: A0A674NUM5
names: Function
names: Similarity
names: Subunit
messages: Auxillary component of the N-terminal acetyltransferase C (NatC) complex which catalyzes acetylation of N-terminal methionine residues.
messages: Belongs to the snRNP Sm proteins family.
messages: Component of the N-terminal acetyltransferase C (NatC) complex, which is composed of NAA35, NAA38 and NAA30.

31033:LOC101066982
gene id: 31033:LOC101066982
uniprot id: A0A674NH54
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

31033:LOC101075588
gene id: 31033:LOC101075588
uniprot id: H2SEU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Cell surface
messages: Endosome
messages: Membrane

31033:mrps10
gene id: 31033:mrps10
uniprot id: H2TC03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Mitochondrion

31033:LOC101077564
gene id: 31033:LOC101077564
uniprot id: H2V6H4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the DNA photolyase class-1 family.
messages: Binds 1 5,10-methenyltetrahydrofolate (MTHF) per subunit.
messages: Binds 1 FAD per subunit.
messages: May have a photoreceptor function.

31033:rps9
gene id: 31033:rps9
uniprot id: H2UUL1
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: Identified in a IGF2BP1-dependent mRNP granule complex containing untranslated mRNAs.

31033:LOC101067801
gene id: 31033:LOC101067801
uniprot id: H2UZ87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

31033:gtf2a1
gene id: 31033:gtf2a1
uniprot id: H2VA00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFIIA subunit 1 family.
messages: Nucleus

31033:elovl7
gene id: 31033:elovl7
uniprot id: A0A674NAA0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELO family. ELOVL7 subfamily.
messages: Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme with higher activity toward C18 acyl-CoAs, especially C18:3(n-3) acyl-CoAs and C18:3(n-6)-CoAs. Also active toward C20:4-, C18:0-, C18:1-, C18:2- and C16:0-CoAs, and weakly toward C20:0-CoA. Little or no activity toward C22:0-, C24:0-, or C26:0-CoAs. May participate to the production of saturated and polyunsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

31033:tlr21
gene id: 31033:tlr21
uniprot id: Q5H724
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Toll-like receptor family.
messages: Membrane

31033:mettl3
gene id: 31033:mettl3
uniprot id: H2UQP4
names: Similarity
messages: Belongs to the MT-A70-like family.

31033:nagk
gene id: 31033:nagk
uniprot id: H2T5Q9
names: Similarity
messages: Belongs to the eukaryotic-type N-acetylglucosamine kinase family.

31033:cth
gene id: 31033:cth
uniprot id: A0A674MWJ6
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

31033:LOC100049643
gene id: 31033:LOC100049643
uniprot id: A1KZS9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. Flotillin subfamily.
messages: Endosome
messages: Heterooligomeric complex.
messages: Membrane

31033:polr2l
gene id: 31033:polr2l
uniprot id: H2V520
names: Similarity
messages: Belongs to the archaeal Rpo10/eukaryotic RPB10 RNA polymerase subunit family.

31033:LOC105416602
gene id: 31033:LOC105416602
uniprot id: A0A3B5JY81
names: Subcellular Location Annotation
messages: Membrane

31033:aasdhppt
gene id: 31033:aasdhppt
uniprot id: H2T654
names: Similarity
messages: Belongs to the P-Pant transferase superfamily. AcpS family.

31033:LOC101076270
gene id: 31033:LOC101076270
uniprot id: A0A674N920
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

31033:fam136a
gene id: 31033:fam136a
uniprot id: H2TN21
names: Similarity
messages: Belongs to the FAM136 family.

31033:pdlim1
gene id: 31033:pdlim1
uniprot id: H2V9A0
names: Subcellular Location Annotation
messages: Z line

31033:atp6v1a
gene id: 31033:atp6v1a
uniprot id: H2RQI3
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.

31033:LOC101073358
gene id: 31033:LOC101073358
uniprot id: A0A3B5JUW3
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

31033:hspa13
gene id: 31033:hspa13
uniprot id: A0A3B5KL77
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 70 family.
messages: Binds UBQLN2.
messages: Endoplasmic reticulum
messages: Has peptide-independent ATPase activity.
messages: Microsome

31033:uhrf1
gene id: 31033:uhrf1
uniprot id: H2TMV9
names: Subcellular Location Annotation
messages: Nucleus

31033:LOC101073063
gene id: 31033:LOC101073063
uniprot id: H2TF55
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RAD23 family.
messages: Cytoplasm
messages: Multiubiquitin chain receptor involved in modulation of proteasomal degradation. Involved in nucleotide excision repair.
messages: Nucleus

31033:slc25a35
gene id: 31033:slc25a35
uniprot id: A0A3B5KI09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

31033:LOC101069811
gene id: 31033:LOC101069811
uniprot id: A0A3B5KF80
names: Similarity
messages: Belongs to the TGF-beta family.

31033:LOC101077344
gene id: 31033:LOC101077344
uniprot id: A0A674NLQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Cationic amino acid transporter (CAT) (TC 2.A.3.3) family.
messages: Cell membrane
messages: Membrane

31033:LOC101062079
gene id: 31033:LOC101062079
uniprot id: H2T5B9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Muscarinic acetylcholine receptor subfamily.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is Pi turnover.

31033:pdpk1
gene id: 31033:pdpk1
uniprot id: H2USE9
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PDPK1 subfamily.

31033:desi1
gene id: 31033:desi1
uniprot id: A0A674NYF0
names: Similarity
messages: Belongs to the DeSI family.

31033:LOC101068145
gene id: 31033:LOC101068145
uniprot id: A0A674P4Q0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rho family. CDC42 subfamily.
messages: Cell membrane
messages: Membrane
messages: Midbody
messages: Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state.

31033:LOC101073513
gene id: 31033:LOC101073513
uniprot id: A0A674PDS0
names: Function
names: Similarity
messages: Belongs to the ferritin family.
messages: Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.

31033:mrps25
gene id: 31033:mrps25
uniprot id: H2TX09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mS25 family.
messages: Mitochondrion

31033:atp2a2
gene id: 31033:atp2a2
uniprot id: A0A674MCU1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIA subfamily.
messages: Catalyzes the hydrolysis of ATP coupled with the transport of calcium.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Sarcoplasmic reticulum membrane

31033:LOC101061635
gene id: 31033:LOC101061635
uniprot id: A0A674MX78
uniprot id: A0A674PNE8
names: Similarity
messages: Belongs to the DOCK family.

31033:LOC101073835
gene id: 31033:LOC101073835
uniprot id: A0A674P3N0
names: Similarity
messages: Belongs to the syntaxin family.

31033:LOC101077479
gene id: 31033:LOC101077479
uniprot id: H2UGI1
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

31033:LOC101079526
gene id: 31033:LOC101079526
uniprot id: A0A3B5KFS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endothelin/sarafotoxin family.
messages: Secreted

31033:rpl30
gene id: 31033:rpl30
uniprot id: A0A674NDI3
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL30 family.

31033:ddit3
gene id: 31033:ddit3
uniprot id: A0A3B5K2B2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family.
messages: Cytoplasm

31033:LOC101064444
gene id: 31033:LOC101064444
uniprot id: H2ST97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TNF receptor-associated factor family.
messages: Cytoplasm

31033:tm2d2
gene id: 31033:tm2d2
uniprot id: H2V040
names: Subcellular Location Annotation
messages: Membrane

31033:mtf2
gene id: 31033:mtf2
uniprot id: H2SJM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Polycomblike family.
messages: Nucleus

31033:LOC101062827
gene id: 31033:LOC101062827
uniprot id: H2UII0
names: Similarity
messages: Belongs to the RimK family.

31033:tafa1
gene id: 31033:tafa1
uniprot id: H2SRM6
names: Similarity
messages: Belongs to the TAFA family.

31033:ptdss2
gene id: 31033:ptdss2
uniprot id: H2UX69
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphatidyl serine synthase family.
messages: Catalyzes a base-exchange reaction in which the polar head group of phosphatidylethanolamine (PE) is replaced by L-serine.
messages: Endoplasmic reticulum membrane
messages: Membrane

31033:sncg
gene id: 31033:sncg
uniprot id: Q3LU28
names: Similarity
names: Subunit
messages: Belongs to the synuclein family.
messages: May be a centrosome-associated protein. Interacts with MYOC; affects its secretion and its aggregation.

31033:tbc1d24
gene id: 31033:tbc1d24
uniprot id: H2UJG0
names: Subcellular Location Annotation
messages: Membrane

31033:apex1
gene id: 31033:apex1
uniprot id: H2SCJ4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Cytoplasm
messages: Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends.
messages: Mitochondrion
messages: Nucleus
messages: Probably binds two magnesium or manganese ions per subunit.

31033:mdm2
gene id: 31033:mdm2
uniprot id: H2T886
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MDM2/MDM4 family.
messages: Cytoplasm
messages: nucleolus
messages: nucleoplasm

31033:ap1g1
gene id: 31033:ap1g1
uniprot id: H2V7V8
names: Similarity
messages: Belongs to the adaptor complexes large subunit family.

31033:ogg1
gene id: 31033:ogg1
uniprot id: H2S698
names: Similarity
messages: Belongs to the type-1 OGG1 family.

31033:dph5
gene id: 31033:dph5
uniprot id: A0A674MF64
names: Function
names: Similarity
messages: Belongs to the diphthine synthase family.
messages: S-adenosyl-L-methionine-dependent methyltransferase that catalyzes four methylations of the modified target histidine residue in translation elongation factor 2 (EF-2), to form an intermediate called diphthine methyl ester. The four successive methylation reactions represent the second step of diphthamide biosynthesis.

31033:slc25a42
gene id: 31033:slc25a42
uniprot id: A0A3B5K3W8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

31033:LOC101062196
gene id: 31033:LOC101062196
uniprot id: H2TV10
names: Similarity
messages: Belongs to the PDGF/VEGF growth factor family.

31033:tbx4
gene id: 31033:tbx4
uniprot id: H2T648
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

31033:ehhadh
gene id: 31033:ehhadh
uniprot id: H2TN79
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.

31033:LOC101077576
gene id: 31033:LOC101077576
uniprot id: A0A3B5KG71
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TFB5 family.
messages: Component of the 7-subunit TFIIH core complex.
messages: In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape.
messages: Nucleus

31033:gab2
gene id: 31033:gab2
uniprot id: H2UBR1
names: Similarity
messages: Belongs to the GAB family.

31033:phf5a
gene id: 31033:phf5a
uniprot id: A0A674P341
names: Similarity
messages: Belongs to the PHF5 family.

31033:LOC101078025
gene id: 31033:LOC101078025
uniprot id: H2U1R6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the junctophilin family.
messages: Endoplasmic reticulum membrane
messages: Membrane

31033:vps52
gene id: 31033:vps52
uniprot id: H2UBE8
names: Similarity
messages: Belongs to the VPS52 family.

31033:LOC101067509
gene id: 31033:LOC101067509
uniprot id: A0A674PNV2
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

31033:tnfaip6
gene id: 31033:tnfaip6
uniprot id: H2UU15
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

31033:ccdc124
gene id: 31033:ccdc124
uniprot id: H2TMA7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CCDC124 family.
messages: Interacts with RASGEF1B.
messages: Required for proper progression of late cytokinetic stages.

31033:txnip
gene id: 31033:txnip
uniprot id: H2S6I9
names: Similarity
messages: Belongs to the arrestin family.

31033:lrp10
gene id: 31033:lrp10
uniprot id: A0A3B5K479
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

31033:cdk4
gene id: 31033:cdk4
uniprot id: A0A674NJC4
names: Similarity
messages: Belongs to the protein kinase superfamily.

31033:plp2
gene id: 31033:plp2
uniprot id: A0A3B5KFT4
names: Subcellular Location Annotation
messages: Membrane

31033:pde1c
gene id: 31033:pde1c
uniprot id: H2U1H1
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family. PDE1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

31033:seh1l
gene id: 31033:seh1l
uniprot id: A0A674NJ21
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat SEC13 family.
messages: Component of the Nup107-160 subcomplex of the nuclear pore complex (NPC). The Nup107-160 subcomplex is required for the assembly of a functional NPC. The Nup107-160 subcomplex is also required for normal kinetochore microtubule attachment, mitotic progression and chromosome segregation. This subunit plays a role in recruitment of the Nup107-160 subcomplex to the kinetochore.
messages: Lysosome membrane
messages: kinetochore

31033:LOC101067847
gene id: 31033:LOC101067847
uniprot id: A0A674PME2
names: Function
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

31033:nqo1
gene id: 31033:nqo1
uniprot id: H2TZ89
names: Similarity
messages: Belongs to the NAD(P)H dehydrogenase (quinone) family.

31033:ddx5
gene id: 31033:ddx5
uniprot id: H2RZ56
names: Similarity
messages: Belongs to the DEAD box helicase family.

31033:popdc2
gene id: 31033:popdc2
uniprot id: H2UUV4
uniprot id: H2UUV6
names: Similarity
messages: Belongs to the popeye family.

31033:LOC101062348
gene id: 31033:LOC101062348
uniprot id: A0A3B5K8V4
names: Similarity
messages: Belongs to the WD repeat G protein beta family.

31033:LOC101064940
gene id: 31033:LOC101064940
uniprot id: H2T574
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane
messages: Sodium-phosphate symporter which plays a fundamental housekeeping role in phosphate transport.

31033:LOC445896
gene id: 31033:LOC445896
uniprot id: Q6PVV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPARC family.
messages: extracellular matrix

31033:LOC101076782
gene id: 31033:LOC101076782
uniprot id: H2VE76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

31033:mpc2
gene id: 31033:mpc2
uniprot id: H2U1Q4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family.
messages: Mediates the uptake of pyruvate into mitochondria.
messages: Membrane
messages: Mitochondrion inner membrane

31033:LOC101065168
gene id: 31033:LOC101065168
uniprot id: A0A674NTS2
names: Similarity
messages: Belongs to the UPF0415 family.

31033:tmem39a
gene id: 31033:tmem39a
uniprot id: H2V3T5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM39 family.
messages: Membrane

31033:pgk1
gene id: 31033:pgk1
uniprot id: H2SMR9
names: Similarity
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Monomer.

31033:rpe
gene id: 31033:rpe
uniprot id: A0A674NX86
names: Cofactor
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.

31033:LOC101069509
gene id: 31033:LOC101069509
uniprot id: H2VE74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

31033:il1rapl1
gene id: 31033:il1rapl1
uniprot id: A0A674N1J1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the interleukin-1 receptor family.
messages: Membrane

31033:fmr1
gene id: 31033:fmr1
uniprot id: A0A674N8X4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FMR1 family.
messages: Cell membrane
messages: Cytoplasmic ribonucleoprotein granule
messages: Membrane
messages: Perikaryon
messages: Presynaptic cell membrane
messages: Synaptic cell membrane
messages: axon
messages: centromere
messages: dendrite
messages: dendritic spine
messages: filopodium tip
messages: growth cone
messages: neuron projection
messages: nucleolus
messages: perinuclear region
messages: synaptosome

31033:ipo7
gene id: 31033:ipo7
uniprot id: H2V5Z3
names: Subcellular Location Annotation
messages: Cytoplasm

31033:tbx21
gene id: 31033:tbx21
uniprot id: H2U7Q0
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

31033:LOC101061276
gene id: 31033:LOC101061276
uniprot id: A0A674ME96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tom40 family.
messages: Membrane
messages: Mitochondrion outer membrane

31033:LOC101070083
gene id: 31033:LOC101070083
uniprot id: H2SDU8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: Homotrimer.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.

31033:gpm6b
gene id: 31033:gpm6b
uniprot id: H2TBY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the myelin proteolipid protein family.
messages: Membrane

31033:LOC101079659
gene id: 31033:LOC101079659
uniprot id: H2SCT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

31033:b4gat1
gene id: 31033:b4gat1
uniprot id: A0A3B5K8M2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 49 family.
messages: Golgi apparatus membrane
messages: Membrane

31033:insig1
gene id: 31033:insig1
uniprot id: A0A3B5KA23
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the INSIG family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mediates feedback control of cholesterol synthesis.
messages: Membrane

31033:med10
gene id: 31033:med10
uniprot id: A0A3B5KIZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 10 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

31033:npm3
gene id: 31033:npm3
uniprot id: H2TXR6
names: Similarity
messages: Belongs to the nucleoplasmin family.

31033:cisd2
gene id: 31033:cisd2
uniprot id: H2TSJ9
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Homodimer.
messages: Mitochondrion outer membrane
messages: Regulator of autophagy that contributes to antagonize becn1-mediated cellular autophagy at the endoplasmic reticulum. Participates in the interaction of bcl2 with becn1 and is required for bcl2-mediated depression of endoplasmic reticulum Ca(2+) stores during autophagy.

31033:vps72
gene id: 31033:vps72
uniprot id: H2SQW8
names: Function
names: Similarity
messages: Belongs to the VPS72/YL1 family.
messages: Deposition-and-exchange histone chaperone specific for H2AZ1, specifically chaperones H2AZ1 and deposits it into nucleosomes. As component of the SRCAP complex, mediates the ATP-dependent exchange of histone H2AZ1/H2B dimers for nucleosomal H2A/H2B, leading to transcriptional regulation of selected genes by chromatin remodeling.

31033:itm2b
gene id: 31033:itm2b
uniprot id: H2UFI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ITM2 family.
messages: Membrane

31033:cul9
gene id: 31033:cul9
uniprot id: A0A674P133
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cullin family.
messages: Cytoplasm

31033:exosc1
gene id: 31033:exosc1
uniprot id: H2T3A0
names: Subcellular Location Annotation
messages: Cytoplasm

31033:LOC101061927
gene id: 31033:LOC101061927
uniprot id: H2TVL8
names: Subcellular Location Annotation
messages: Membrane

31033:ccnc
gene id: 31033:ccnc
uniprot id: H2UMX4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cyclin family. Cyclin AB subfamily.
messages: Belongs to the cyclin family. Cyclin C subfamily.
messages: Component of the Mediator complex, a coactivator involved in regulated gene transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. Binds to and activates cyclin-dependent kinase CDK8 that phosphorylates the CTD (C-terminal domain) of the large subunit of RNA polymerase II (RNAp II), which may inhibit the formation of a transcription initiation complex.
messages: Nucleus

31033:dipk2a
gene id: 31033:dipk2a
uniprot id: A0A3B5KQ20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DIPK family.
messages: Secreted

31033:tmcc1
gene id: 31033:tmcc1
uniprot id: A0A3B5KDF7
uniprot id: A0A3B5KI44
uniprot id: H2TVW7
names: Similarity
messages: Belongs to the TEX28 family.

31033:hoxd10
gene id: 31033:hoxd10
uniprot id: H2V6U0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

31033:vps28
gene id: 31033:vps28
uniprot id: A0A674PFG7
names: Function
names: Similarity
messages: Belongs to the VPS28 family.
messages: Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process.

31033:LOC101062466
gene id: 31033:LOC101062466
uniprot id: H2SHS0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ETF beta-subunit/FixA family.
messages: Heterodimer of an alpha and a beta subunit.
messages: Mitochondrion matrix
messages: The electron transfer flavoprotein serves as a specific electron acceptor for several dehydrogenases, including five acyl-CoA dehydrogenases, glutaryl-CoA and sarcosine dehydrogenase. It transfers the electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

31033:LOC101068178
gene id: 31033:LOC101068178
uniprot id: A0A674PCC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MRAP family.
messages: Endoplasmic reticulum membrane
messages: Membrane

31033:eml4
gene id: 31033:eml4
uniprot id: H2SVC1
names: Similarity
messages: Belongs to the WD repeat EMAP family.

31033:aimp2
gene id: 31033:aimp2
uniprot id: A0A674NTG6
names: Subcellular Location Annotation
messages: Nucleus
messages: cytosol

31033:fut9
gene id: 31033:fut9
uniprot id: Q70AH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 10 family.
messages: Golgi stack membrane

31033:atp5f1a
gene id: 31033:atp5f1a
uniprot id: A0A3B5K2L0
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

31033:irf6
gene id: 31033:irf6
uniprot id: H2SXC8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IRF family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

31033:LOC101079431
gene id: 31033:LOC101079431
uniprot id: H2TSX0
names: Similarity
messages: Belongs to the WD repeat ARPC1 family.

31033:LOC101074708
gene id: 31033:LOC101074708
uniprot id: H2T4Y1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

31033:fgfr1op2
gene id: 31033:fgfr1op2
uniprot id: H2SE25
names: Similarity
messages: Belongs to the SIKE family.

31033:LOC101075028
gene id: 31033:LOC101075028
uniprot id: H2UZH8
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

31033:LOC101073509
gene id: 31033:LOC101073509
uniprot id: A0A3B5K2Q9
names: Similarity
messages: Belongs to the DEAD box helicase family.

31033:LOC101075951
gene id: 31033:LOC101075951
uniprot id: A0A674MKM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Cytoplasm
messages: Nucleus

31033:LOC101074797
gene id: 31033:LOC101074797
uniprot id: Q6E5Q2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

31033:LOC101061771
gene id: 31033:LOC101061771
uniprot id: A0A3B5KPC4
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus
messages: Secreted

31033:polr2j
gene id: 31033:polr2j
uniprot id: A0A674NLW5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal Rpo11/eukaryotic RPB11/RPC19 RNA polymerase subunit family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB11 is part of the core element with the central large cleft.
messages: Nucleus

31033:ap1m2
gene id: 31033:ap1m2
uniprot id: A0A3B5KB89
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes medium subunit family.
messages: Golgi apparatus
messages: Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules.
messages: clathrin-coated vesicle membrane

31033:LOC101063278
gene id: 31033:LOC101063278
uniprot id: A0A674P6F0
names: Subcellular Location Annotation
messages: Nucleus

31033:amotl2
gene id: 31033:amotl2
uniprot id: H2SEB3
names: Similarity
messages: Belongs to the angiomotin family.

31033:prkra
gene id: 31033:prkra
uniprot id: H2V637
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRKRA family.
messages: perinuclear region

31033:spg7
gene id: 31033:spg7
uniprot id: H2V4S3
names: Similarity
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the N-terminal section; belongs to the AAA ATPase family.

31033:LOC101064704
gene id: 31033:LOC101064704
uniprot id: H2V4T3
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

31033:tube1
gene id: 31033:tube1
uniprot id: A0A3B5KC14
names: Similarity
messages: Belongs to the tubulin family.

31033:ppp2r3c
gene id: 31033:ppp2r3c
uniprot id: A0A674NT51
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

31033:pepd
gene id: 31033:pepd
uniprot id: H2RRC7
names: Similarity
messages: Belongs to the peptidase M24B family.

31033:LOC101076884
gene id: 31033:LOC101076884
uniprot id: H2RUY8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H4 family.
messages: Chromosome
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

31033:LOC101064701
gene id: 31033:LOC101064701
uniprot id: H2SI11
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

31033:acot8
gene id: 31033:acot8
uniprot id: H2RQ17
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

31033:LOC101069649
gene id: 31033:LOC101069649
uniprot id: H2UHS7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

31033:smco4
gene id: 31033:smco4
uniprot id: Q9I859
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMCO4 family.
messages: Membrane

31033:rnf114
gene id: 31033:rnf114
uniprot id: A0A3B5K4L3
names: Subunit
messages: Interacts with XAF1, the interaction increases XAF1 stability and proapoptotic effects, and may regulate IFN signaling.

31033:uba52
gene id: 31033:uba52
uniprot id: H2SBM2
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the eukaryotic ribosomal protein eL40 family.
messages: In the N-terminal section; belongs to the ubiquitin family.
messages: Nucleus

31033:pola1
gene id: 31033:pola1
uniprot id: H2T555
names: Similarity
messages: Belongs to the DNA polymerase type-B family.

31033:agps
gene id: 31033:agps
uniprot id: Q1KKS4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FAD-binding oxidoreductase/transferase type 4 family.
messages: Catalyzes the exchange of an acyl for a long-chain alkyl group and the formation of the ether bond in the biosynthesis of ether phospholipids.
messages: Homodimer.
messages: Peroxisome

31033:impad1
gene id: 31033:impad1
uniprot id: H2T0G9
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

31033:bri3
gene id: 31033:bri3
uniprot id: A0A674NC06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BRI3 family.
messages: Membrane
messages: perinuclear region

31033:hspb8
gene id: 31033:hspb8
uniprot id: H2UWV9
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

31033:ppih
gene id: 31033:ppih
uniprot id: H2UQR6
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

31033:rhcg2
gene id: 31033:rhcg2
uniprot id: Q7T3R4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
names: Tissue Specificity
messages: Apicolateral cell membrane
messages: Belongs to the ammonium transporter (TC 2.A.49) family. Rh subfamily.
messages: Functions as an ammonia transporter. May play a role in the elimination of ammonia in the gill.
messages: Homotrimer.
messages: Specifically expressed in the gill by pavement cells (at protein level).

31033:LOC101066900
gene id: 31033:LOC101066900
uniprot id: H2TRA8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ARPC4 family.
messages: Cell projection
messages: Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament.
messages: cytoskeleton

31033:rrad
gene id: 31033:rrad
uniprot id: H2V4P1
names: Similarity
messages: Belongs to the small GTPase superfamily. RGK family.

31033:LOC101068196
gene id: 31033:LOC101068196
uniprot id: A0A674PEU6
names: Subcellular Location Annotation
messages: Membrane

31033:fbxo45
gene id: 31033:fbxo45
uniprot id: H2SXP9
names: Similarity
messages: Belongs to the FBXO45/Fsn family.

31033:LOC101076371
gene id: 31033:LOC101076371
uniprot id: H2U3W2
names: Similarity
messages: Belongs to the TEX28 family.

31033:LOC101070662
gene id: 31033:LOC101070662
uniprot id: H2TA25
names: Similarity
messages: Belongs to the PDGF/VEGF growth factor family.

31033:rfrp
gene id: 31033:rfrp
uniprot id: Q05KN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FARP (FMRFamide related peptide) family.
messages: Secreted

31033:ankh
gene id: 31033:ankh
uniprot id: H2T9R1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ANKH family.
messages: Membrane
messages: Regulates intra- and extracellular levels of inorganic pyrophosphate (PPi), probably functioning as PPi transporter.

31033:mthfs
gene id: 31033:mthfs
uniprot id: A0A3B5KFU0
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

31033:ss18
gene id: 31033:ss18
uniprot id: H2TD73
uniprot id: H2TD74
names: Similarity
messages: Belongs to the SS18 family.

31033:LOC101072385
gene id: 31033:LOC101072385
uniprot id: H2TCA9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM38 family.
messages: Membrane
messages: Monovalent cation channel required for maintenance of rapid intracellular calcium release. May act as a potassium counter-ion channel that functions in synchronization with calcium release from intracellular stores.

31033:LOC101064450
gene id: 31033:LOC101064450
uniprot id: H2V1I8
names: Function
names: Similarity
messages: Belongs to the parvalbumin family.
messages: In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions.

31033:LOC101067019
gene id: 31033:LOC101067019
uniprot id: A0A674MUD3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lin-7 family.
messages: Cell junction
messages: Cell membrane
messages: Membrane
messages: Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells.

31033:smim15
gene id: 31033:smim15
uniprot id: H2UFJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMIM15 family.
messages: Membrane

31033:LOC101063432
gene id: 31033:LOC101063432
uniprot id: H2RU44
names: Similarity
messages: Belongs to the calycin superfamily. Lipocalin family.

31033:LOC101073582
gene id: 31033:LOC101073582
uniprot id: H2T759
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

31033:cct8
gene id: 31033:cct8
uniprot id: H2V3Z2
uniprot id: H2V3Z3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCP-1 chaperonin family.
messages: cilium basal body

31033:LOC101078143
gene id: 31033:LOC101078143
uniprot id: A0A3B5JZJ1
names: Subcellular Location Annotation
names: Subunit
messages: Efficient DNA binding requires dimerization with another bHLH protein. Binds DNA as a heterodimer with MAX.
messages: Nucleus

31033:xk
gene id: 31033:xk
uniprot id: Q5GH53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XK family.
messages: Membrane

31033:ef-1a
gene id: 31033:ef-1a
uniprot id: Q4JF82
names: Function
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

31033:LOC101063453
gene id: 31033:LOC101063453
uniprot id: A0A674PBH9
names: Subcellular Location Annotation
messages: Membrane

31033:acmsd
gene id: 31033:acmsd
uniprot id: H2T582
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. ACMSD family.
messages: Converts alpha-amino-beta-carboxymuconate-epsilon-semialdehyde (ACMS) to alpha-aminomuconate semialdehyde (AMS). ACMS can be converted non-enzymatically to quinolate (QA), a key precursor of NAD, and a potent endogenous excitotoxin of neuronal cells which is implicated in the pathogenesis of various neurodegenerative disorders. In the presence of ACMSD, ACMS is converted to AMS, a benign catabolite. ACMSD ultimately controls the metabolic fate of tryptophan catabolism along the kynurenine pathway.
messages: Monomer.

31033:syndig1
gene id: 31033:syndig1
uniprot id: H2S8X3
names: Similarity
messages: Belongs to the CD225/Dispanin family.

31033:LOC101065188
gene id: 31033:LOC101065188
uniprot id: A0A674MJ21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CART family.
messages: Secreted

31033:tmbim1
gene id: 31033:tmbim1
uniprot id: H2TLA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

31033:bmp5
gene id: 31033:bmp5
uniprot id: H2UQZ9
names: Similarity
messages: Belongs to the TGF-beta family.

31033:ccnl1
gene id: 31033:ccnl1
uniprot id: H2U6Q3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cyclin family. Cyclin AB subfamily.
messages: Belongs to the cyclin family. Cyclin L subfamily.
messages: Essential for the control of the cell cycle at the G2/M (mitosis) transition.
messages: Interacts with the CDK1 protein kinase to form a serine/threonine kinase holoenzyme complex also known as maturation promoting factor (MPF). The cyclin subunit imparts substrate specificity to the complex.
messages: Nucleus speckle
messages: nucleoplasm

31033:tmem9
gene id: 31033:tmem9
uniprot id: H2UBV5
names: Similarity
messages: Belongs to the TMEM9 family.

31033:LOC101062556
gene id: 31033:LOC101062556
uniprot id: A0A3B5K8J7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Endosome membrane
messages: Membrane

31033:uckl1
gene id: 31033:uckl1
uniprot id: H2SBQ6
names: Similarity
messages: Belongs to the uridine kinase family.

31033:ppp4r2
gene id: 31033:ppp4r2
uniprot id: H2THS9
names: Similarity
messages: Belongs to the PPP4R2 family.

31033:glce
gene id: 31033:glce
uniprot id: A0A3B5KTY5
names: Similarity
messages: Belongs to the D-glucuronyl C5-epimerase family.

31033:mapre3
gene id: 31033:mapre3
uniprot id: H2TFC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAPRE family.
messages: cytoskeleton

31033:skap2
gene id: 31033:skap2
uniprot id: Q1KKZ1
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SKAP family.
messages: Cytoplasm
messages: May be involved in B-cell and macrophage adhesion processes. May play a role in src signaling pathway (By similarity).
messages: Phosphorylated on tyrosines.

31033:klhl15
gene id: 31033:klhl15
uniprot id: A0A674N115
uniprot id: A0A674PHS1
names: Subcellular Location Annotation
messages: Nucleus

31033:LOC101062700
gene id: 31033:LOC101062700
uniprot id: A0A674P1W7
names: Subcellular Location Annotation
messages: Early endosome
messages: Endosome

31033:LOC101062359
gene id: 31033:LOC101062359
uniprot id: A0A674M9Y9
names: Subcellular Location Annotation
messages: Membrane

31033:ephb3
gene id: 31033:ephb3
uniprot id: H2SYD0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

31033:slc8b1
gene id: 31033:slc8b1
uniprot id: A0A3B5KDP7
names: Subcellular Location Annotation
messages: Membrane

31033:LOC101078369
gene id: 31033:LOC101078369
uniprot id: A0A674MZZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 99 family.
messages: Golgi apparatus membrane
messages: Membrane

31033:ltbp3
gene id: 31033:ltbp3
uniprot id: H2V0P3
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

31033:chrm2
gene id: 31033:chrm2
uniprot id: Q66LI8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Muscarinic acetylcholine receptor subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane
messages: The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins.

31033:LOC101063778
gene id: 31033:LOC101063778
uniprot id: A0A3B5K329
names: Subcellular Location Annotation
messages: Early endosome
messages: Endosome

31033:wnt8
gene id: 31033:wnt8
uniprot id: Q6E0H1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

31033:LOC101065464
gene id: 31033:LOC101065464
uniprot id: H2VB22
names: Subcellular Location Annotation
messages: Membrane

31033:eef1akmt1
gene id: 31033:eef1akmt1
uniprot id: H2UU60
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. EFM5 family.
messages: Cytoplasm
messages: Protein-lysine methyltransferase that selectively catalyzes the trimethylation of EEF1A at 'Lys-79'.
messages: Was originally thought to be an N(6)-adenine-specific DNA methyltransferase based on primary sequence and predicted secondary structure.

31033:st6galnac3
gene id: 31033:st6galnac3
uniprot id: Q50J45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

31033:met
gene id: 31033:met
uniprot id: Q9YGM7
names: Caution
names: Subcellular Location Annotation
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

31033:armc1
gene id: 31033:armc1
uniprot id: A0A674PF83
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In association with mitochondrial contact site and cristae organizing system (MICOS) complex components and mitochondrial outer membrane sorting assembly machinery (SAM) complex components may regulate mitochondrial dynamics playing a role in determining mitochondrial length, distribution and motility.
messages: Membrane
messages: Mitochondrion outer membrane

31033:LOC101070011
gene id: 31033:LOC101070011
uniprot id: A0A3B5KC04
names: Similarity
messages: Belongs to the G-alpha family. G(q) subfamily.

31033:actr10
gene id: 31033:actr10
uniprot id: H2TVB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the actin family.
messages: cytoskeleton

31033:LOC101078790
gene id: 31033:LOC101078790
uniprot id: A0A674MSX0
uniprot id: H2UD12
names: Similarity
messages: Belongs to the transglutaminase superfamily. Transglutaminase family.

31033:erbb3
gene id: 31033:erbb3
uniprot id: H2TXM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. EGF receptor subfamily.
messages: Membrane

31033:LOC101070601
gene id: 31033:LOC101070601
uniprot id: A0A674MBW3
names: Similarity
messages: Belongs to the class I fructose-bisphosphate aldolase family.

31033:slc35b3
gene id: 31033:slc35b3
uniprot id: A0A3B5JWU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide-sugar transporter family. SLC35B subfamily.
messages: Membrane

31033:LOC101063780
gene id: 31033:LOC101063780
uniprot id: A0A674PHS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ubiquitin family. SUMO subfamily.
messages: Nucleus

31033:nkd1
gene id: 31033:nkd1
uniprot id: H2T7P1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NKD family.
messages: Cell autonomous antagonist of the canonical Wnt signaling pathway.
messages: Cell membrane
messages: Cytoplasm
messages: Membrane

31033:c8h20orf27
gene id: 31033:c8h20orf27
uniprot id: A0A3B5KGQ3
names: Similarity
messages: Belongs to the UPF0687 family.

31033:ndufb4
gene id: 31033:ndufb4
uniprot id: A0A674MFB8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFB4 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

31033:LOC101079967
gene id: 31033:LOC101079967
uniprot id: A0A3B5KJH4
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

31033:LOC101078308
gene id: 31033:LOC101078308
uniprot id: A0A674NFM8
uniprot id: H2SZZ4
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.

31033:adra1b
gene id: 31033:adra1b
uniprot id: H2RQJ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Cytoplasm
messages: Membrane
messages: This alpha-adrenergic receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Its effect is mediated by G(q) and G(11) proteins. Nuclear ADRA1A-ADRA1B heterooligomers regulate phenylephrine (PE)-stimulated ERK signaling in cardiac myocytes.
messages: caveola

31033:pycr3
gene id: 31033:pycr3
uniprot id: A0A3B5KMV6
names: Similarity
messages: Belongs to the pyrroline-5-carboxylate reductase family.

31033:LOC101077778
gene id: 31033:LOC101077778
uniprot id: A0A3B5KHB2
names: Similarity
messages: Belongs to the cyclin family. Cyclin AB subfamily.

31033:ncor1
gene id: 31033:ncor1
uniprot id: A0A674NUJ6
names: Similarity
messages: Belongs to the N-CoR nuclear receptor corepressors family.

31033:tmem178b
gene id: 31033:tmem178b
uniprot id: H2U0E8
names: Similarity
messages: Belongs to the TMEM178 family.

31033:slc1a7
gene id: 31033:slc1a7
uniprot id: A0A674N9F1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

31033:psmg1
gene id: 31033:psmg1
uniprot id: H2RYL9
names: Similarity
messages: Belongs to the PSMG1 family.

31033:LOC101074826
gene id: 31033:LOC101074826
uniprot id: A0A674MIU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Membrane

31033:ube2f
gene id: 31033:ube2f
uniprot id: H2T1W2
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

31033:csnk1a1
gene id: 31033:csnk1a1
uniprot id: A0A3B5KVB5
uniprot id: A0A674MKV3
names: Similarity
messages: Belongs to the protein kinase superfamily.

31033:rab5if
gene id: 31033:rab5if
uniprot id: A0A3B5JZA1
names: Subcellular Location Annotation
messages: Membrane

31033:sncb
gene id: 31033:sncb
uniprot id: Q3LU30
names: Similarity
messages: Belongs to the synuclein family.

31033:LOC101076444
gene id: 31033:LOC101076444
uniprot id: H2UHG6
names: Similarity
messages: Belongs to the FAH family.

31033:LOC101063446
gene id: 31033:LOC101063446
uniprot id: H2VC42
names: Similarity
messages: Belongs to the bZIP family. Maf subfamily.

31033:LOC101069728
gene id: 31033:LOC101069728
uniprot id: H2RQZ0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

31033:LOC101063077
gene id: 31033:LOC101063077
uniprot id: H2UUH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the E2F/DP family.
messages: Nucleus

31033:stat3
gene id: 31033:stat3
uniprot id: A0A3B5K909
uniprot id: A0A3B5KEM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transcription factor STAT family.
messages: Cytoplasm
messages: Nucleus

31033:LOC101063668
gene id: 31033:LOC101063668
uniprot id: H2SVK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GLI C2H2-type zinc-finger protein family.
messages: Nucleus

31033:LOC101066582
gene id: 31033:LOC101066582
uniprot id: H2V9P9
names: Similarity
messages: Belongs to the calycin superfamily. Lipocalin family.

31033:LOC101064504
gene id: 31033:LOC101064504
uniprot id: A0A3B5KDX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor Fz/Smo family.
messages: Membrane

31033:fam126a
gene id: 31033:fam126a
uniprot id: H2TBH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM126 family.
messages: Cell membrane
messages: Membrane
messages: cytosol

31033:tfdp1
gene id: 31033:tfdp1
uniprot id: H2U8K4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the E2F/DP family.
messages: Nucleus

31033:LOC101072757
gene id: 31033:LOC101072757
uniprot id: A0A674PG23
uniprot id: H2U9V1
names: Subcellular Location Annotation
messages: Membrane

31033:cog7
gene id: 31033:cog7
uniprot id: H2UGQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COG7 family.
messages: Golgi apparatus membrane
messages: Membrane

31033:fam91a1
gene id: 31033:fam91a1
uniprot id: H2T3S3
names: Similarity
messages: Belongs to the FAM91 family.

31033:LOC101071119
gene id: 31033:LOC101071119
uniprot id: H2TB59
names: Similarity
messages: Belongs to the popeye family.

31033:tlr22
gene id: 31033:tlr22
uniprot id: A8QMS2
uniprot id: Q5H723
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Toll-like receptor family.
messages: Membrane

31033:LOC101063536
gene id: 31033:LOC101063536
uniprot id: H2USK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family.
messages: Nucleus

31033:LOC101064901
gene id: 31033:LOC101064901
uniprot id: H2TTS8
names: Similarity
names: Subunit
messages: Homodimer.
messages: In the C-terminal section; belongs to the phosphoglycerate mutase family.

31033:ccdc93
gene id: 31033:ccdc93
uniprot id: H2UGP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCDC93 family.
messages: Early endosome

31033:lancl1
gene id: 31033:lancl1
uniprot id: H2TCD3
names: Similarity
messages: Belongs to the LanC-like protein family.

31033:cwc25
gene id: 31033:cwc25
uniprot id: H2SF70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CWC25 family.
messages: Nucleus

31033:mb
gene id: 31033:mb
uniprot id: H2RIW6
names: Function
names: Similarity
messages: Belongs to the globin family.
messages: Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles.

31033:mrpl20
gene id: 31033:mrpl20
uniprot id: A0A674P273
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.

31033:LOC101069325
gene id: 31033:LOC101069325
uniprot id: A0A674PEX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

31033:cluh
gene id: 31033:cluh
uniprot id: H2UU85
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CLU family.
messages: Cytoplasm
messages: Cytoplasmic granule
messages: mRNA-binding protein involved in proper cytoplasmic distribution of mitochondria. Specifically binds mRNAs of nuclear-encoded mitochondrial proteins in the cytoplasm and regulates transport or translation of these transcripts close to mitochondria, playing a role in mitochondrial biogenesis.

31033:tada2a
gene id: 31033:tada2a
uniprot id: A0A3B5K7W0
names: Subcellular Location Annotation
messages: Nucleus

31033:pofut2
gene id: 31033:pofut2
uniprot id: A0A3B5K6P6
names: Similarity
messages: Belongs to the glycosyltransferase 68 family.

31033:mrpl32
gene id: 31033:mrpl32
uniprot id: H2UI20
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

31033:stx4
gene id: 31033:stx4
uniprot id: H2TV56
names: Similarity
messages: Belongs to the syntaxin family.

31033:tjap1
gene id: 31033:tjap1
uniprot id: H2S4M0
names: Subcellular Location Annotation
messages: Membrane

31033:LOC101079525
gene id: 31033:LOC101079525
uniprot id: H2TQR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the teashirt C2H2-type zinc-finger protein family.
messages: Nucleus

31033:LOC101067689
gene id: 31033:LOC101067689
uniprot id: A0A3B5JZJ6
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

31033:enkur
gene id: 31033:enkur
uniprot id: H2TFA1
names: Subcellular Location Annotation
messages: cilium axoneme

31033:LOC101066275
gene id: 31033:LOC101066275
uniprot id: A0A3B5K2F7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase VIIb family.
messages: Membrane
messages: Mitochondrion inner membrane

31033:eif3a
gene id: 31033:eif3a
uniprot id: H2V8Z7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit A family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M.
messages: Cytoplasm
messages: RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.

31033:dlst
gene id: 31033:dlst
uniprot id: H2VCN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Mitochondrion matrix

31033:scgn
gene id: 31033:scgn
uniprot id: A0A3B5JY92
names: Subcellular Location Annotation
messages: Cytoplasm

31033:rpl7
gene id: 31033:rpl7
uniprot id: A0A674NKS7
names: Similarity
messages: Belongs to the universal ribosomal protein uL30 family.

31033:best3
gene id: 31033:best3
uniprot id: A0A674NGH3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bestrophin family.
messages: Cell membrane
messages: Forms chloride channels.
messages: Membrane

31033:LOC101065046
gene id: 31033:LOC101065046
uniprot id: H2TWL2
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

31033:LOC101072885
gene id: 31033:LOC101072885
uniprot id: P53480
names: Function
names: Miscellaneous
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
names: Tissue Specificity
messages: Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.
messages: Belongs to the actin family.
messages: In vertebrates 3 main groups of actin isoforms, alpha, beta and gamma have been identified. The alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. The beta and gamma actins coexist in most cell types as components of the cytoskeleton and as mediators of internal cell motility.
messages: Monomethylation at Lys-86 (K86me1) regulates actin-myosin interaction and actomyosin-dependent processes. Demethylation by ALKBH4 is required for maintaining actomyosin dynamics supporting normal cleavage furrow ingression during cytokinesis and cell migration.
messages: Oxidation of Met-46 and Met-49 by MICALs (MICAL1, MICAL2 or MICAL3) to form methionine sulfoxide promotes actin filament depolymerization. MICAL1 and MICAL2 produce the (R)-S-oxide form. The (R)-S-oxide form is reverted by MSRB1 and MSRB2, which promotes actin repolymerization.
messages: Polymerization of globular actin (G-actin) leads to a structural filament (F-actin) in the form of a two-stranded helix. Each actin can bind to 4 others.
messages: Predominantly expressed in heart. Lower levels in skeletal muscle and skin.
messages: There are three genes coding for cardiac actin in Fugu.
messages: cytoskeleton

31033:lypla2
gene id: 31033:lypla2
uniprot id: A0A674NT07
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 2 family.

31033:LOC101063217
gene id: 31033:LOC101063217
uniprot id: H2U704
names: Subcellular Location Annotation
messages: Membrane

31033:foxb2
gene id: 31033:foxb2
uniprot id: A0A3B5K816
names: Subcellular Location Annotation
messages: Nucleus

31033:ncdn
gene id: 31033:ncdn
uniprot id: H2TDL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurochondrin family.
messages: Postsynapse

31033:LOC101078944
gene id: 31033:LOC101078944
uniprot id: H2TBK8
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

31033:LOC101078052
gene id: 31033:LOC101078052
uniprot id: A0A674NPC2
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

31033:polb
gene id: 31033:polb
uniprot id: H2UYD9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-X family.
messages: Cytoplasm
messages: DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template-independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.
messages: Nucleus
messages: Repair polymerase that plays a key role in base-excision repair. Has 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity that removes the 5' sugar phosphate and also acts as a DNA polymerase that adds one nucleotide to the 3' end of the arising single-nucleotide gap. Conducts 'gap-filling' DNA synthesis in a stepwise distributive fashion rather than in a processive fashion as for other DNA polymerases.

31033:trappc5
gene id: 31033:trappc5
uniprot id: A0A3B5KE80
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAPP small subunits family. BET3 subfamily.
messages: Endoplasmic reticulum
messages: May play a role in vesicular transport from endoplasmic reticulum to Golgi.
messages: Part of the multisubunit TRAPP (transport protein particle) complex.
messages: cis-Golgi network

31033:micos13
gene id: 31033:micos13
uniprot id: A0A3B5KD43
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MICOS complex subunit Mic13 family.
messages: Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
messages: Component of the mitochondrial contact site and cristae organizing system (MICOS) complex.
messages: Membrane
messages: Mitochondrion inner membrane

31033:tub
gene id: 31033:tub
uniprot id: H2V5Q2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TUB family.
messages: Secreted

31033:pkn1
gene id: 31033:pkn1
uniprot id: H2S713
uniprot id: H2S715
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
messages: Nucleus

31033:LOC101078795
gene id: 31033:LOC101078795
uniprot id: H2UCX0
names: Subcellular Location Annotation
messages: Synapse

31033:LOC101076253
gene id: 31033:LOC101076253
uniprot id: A0A3B5K339
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase inhibitor family.
messages: Endogenous F(1)F(o)-ATPase inhibitor limiting ATP depletion when the mitochondrial membrane potential falls below a threshold and the F(1)F(o)-ATP synthase starts hydrolyzing ATP to pump protons out of the mitochondrial matrix. Required to avoid the consumption of cellular ATP when the F(1)F(o)-ATP synthase enzyme acts as an ATP hydrolase.
messages: Forms an alpha-helical dimer with monomers associated via an antiparallel alpha-helical coiled coil, leaving each N-terminal inhibitory region accessible for interaction with an F1 catalytic domain. The inhibitory N-terminal region binds the alpha(ADP-bound)-beta(ADP-bound) (ATP5F1A-ATP5F1B) interface of F1-ATPase, and also contact the central gamma subunit (ATP5F1C). This dimeric state is favored by pH values below 7.0, and at higher values the dimers associate to form inactive homotetramer, where the inhibitory region is occluded, masking its inhibitory activity.
messages: Homodimer; represents the active form and is present at a pH value below 6.5. Homotetramer; represents the inactive form and is present at a pH value above 7.0.
messages: Indirectly acts as a regulator of heme synthesis in erythroid tissues: regulates heme synthesis by modulating the mitochondrial pH and redox potential, allowing fech to efficiently catalyze the incorporation of iron into protoporphyrin IX to produce heme.
messages: Mitochondrion

31033:pxmp4
gene id: 31033:pxmp4
uniprot id: H2VDF3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxisomal membrane protein PXMP2/4 family.
messages: Interacts with PEX19.
messages: Peroxisome membrane

31033:prkcq
gene id: 31033:prkcq
uniprot id: H2TZU4
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.

31033:sptssb
gene id: 31033:sptssb
uniprot id: H2SPY6
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

31033:tbc1d23
gene id: 31033:tbc1d23
uniprot id: H2TVU1
names: Subcellular Location Annotation
messages: trans-Golgi network

31033:utp23
gene id: 31033:utp23
uniprot id: A0A674MSM1
names: Subcellular Location Annotation
messages: nucleolus

31033:LOC101079149
gene id: 31033:LOC101079149
uniprot id: A0A3B5KGL3
names: Function
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

31033:LOC115246436
gene id: 31033:LOC115246436
uniprot id: H2TAR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

31033:LOC101079102
gene id: 31033:LOC101079102
uniprot id: H2SCU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calycin superfamily. Lipocalin family.
messages: Secreted

31033:acaa2
gene id: 31033:acaa2
uniprot id: H2UYK5
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

31033:LOC101078904
gene id: 31033:LOC101078904
uniprot id: A0A3B5K5W8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

31033:sugt1
gene id: 31033:sugt1
uniprot id: H2TES5
names: Similarity
messages: Belongs to the SGT1 family.

31033:zc3hc1
gene id: 31033:zc3hc1
uniprot id: A0A3B5KFE6
names: Subcellular Location Annotation
messages: Nucleus

31033:phka2
gene id: 31033:phka2
uniprot id: H2V3F0
uniprot id: H2V3F4
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Although the final Cys may be farnesylated, the terminal tripeptide is probably not removed, and the C-terminus is not methylated.
messages: Belongs to the phosphorylase b kinase regulatory chain family.
messages: Cell membrane
messages: Membrane
messages: Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. The alpha chain may bind calmodulin.

31033:cad
gene id: 31033:cad
uniprot id: A0A674NCI2
names: Similarity
messages: In the central section; belongs to the metallo-dependent hydrolases superfamily. DHOase family. CAD subfamily.

31033:ganab
gene id: 31033:ganab
uniprot id: A0A674NYR6
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

31033:LOC101074394
gene id: 31033:LOC101074394
uniprot id: H2TXE3
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

31033:mtnr1a
gene id: 31033:mtnr1a
uniprot id: A0A674PRZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: High affinity receptor for melatonin. The activity of this receptor is mediated by pertussis toxin sensitive G proteins that inhibits adenylate cyclase activity.
messages: Membrane

31033:nkiras2
gene id: 31033:nkiras2
uniprot id: A0A674MTI8
names: Similarity
messages: Belongs to the small GTPase superfamily. Ras family. KappaB-Ras subfamily.

31033:lsm14b
gene id: 31033:lsm14b
uniprot id: H2RTQ3
names: Similarity
messages: Belongs to the LSM14 family.

31033:casr
gene id: 31033:casr
uniprot id: O73635
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

31033:glo1
gene id: 31033:glo1
uniprot id: A0A674MCW1
names: Function
names: Similarity
messages: Belongs to the glyoxalase I family.
messages: Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.

31033:LOC101072459
gene id: 31033:LOC101072459
uniprot id: H2TEH1
uniprot id: H2TEH2
uniprot id: H2TEH3
names: Function
names: Subcellular Location Annotation
messages: Adapter protein that links membrane-bound small G-proteins to cytoplasmic effector proteins. Necessary for CDC42-mediated reorganization of the actin cytoskeleton and for RAC1-mediated membrane ruffling. Involved in the regulation of the actin cytoskeleton by WASF family members and the Arp2/3 complex. Plays a role in neurite growth. Acts syngeristically with ENAH to promote filipodia formation. Plays a role in the reorganization of the actin cytoskeleton in response to bacterial infection. Participates in actin bundling when associated with EPS8, promoting filopodial protrusions.
messages: Membrane
messages: cytoskeleton
messages: filopodium
messages: ruffle

31033:LOC101066813
gene id: 31033:LOC101066813
uniprot id: A0A674N2X2
names: Similarity
messages: Belongs to the syntaxin family.

31033:gpr1
gene id: 31033:gpr1
uniprot id: H2V5Z4
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

31033:xkr8
gene id: 31033:xkr8
uniprot id: Q5GH46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XK family.
messages: Membrane

31033:ppp1r21
gene id: 31033:ppp1r21
uniprot id: H2UDY7
names: Subcellular Location Annotation
messages: Early endosome
messages: Endosome

31033:LOC446015
gene id: 31033:LOC446015
uniprot id: H2SSZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

31033:cpne3
gene id: 31033:cpne3
uniprot id: H2TIA0
names: Similarity
messages: Belongs to the copine family.

31033:rhbdl3
gene id: 31033:rhbdl3
uniprot id: A0A674P3B4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S54 family.
messages: May be involved in regulated intramembrane proteolysis and the subsequent release of functional polypeptides from their membrane anchors.
messages: Membrane

31033:st6gal1
gene id: 31033:st6gal1
uniprot id: Q6KB62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

31033:gipc2
gene id: 31033:gipc2
uniprot id: H2SC34
names: Similarity
messages: Belongs to the GIPC family.

31033:tmem244
gene id: 31033:tmem244
uniprot id: A0A3B5KBS2
names: Subcellular Location Annotation
messages: Membrane

31033:LOC101063159
gene id: 31033:LOC101063159
uniprot id: H2TVL4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone deacetylase family. HD type 2 subfamily.
messages: Nucleus
messages: Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.

31033:cpt2
gene id: 31033:cpt2
uniprot id: H2V041
names: Similarity
messages: Belongs to the carnitine/choline acetyltransferase family.

31033:ube4b
gene id: 31033:ube4b
uniprot id: H2TTD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ubiquitin conjugation factor E4 family.
messages: Cytoplasm

31033:tubgcp4
gene id: 31033:tubgcp4
uniprot id: H2UBS6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TUBGCP family.
messages: Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome.
messages: centrosome

31033:LOC101070734
gene id: 31033:LOC101070734
uniprot id: H2UR47
names: Similarity
messages: Belongs to the eukaryotic diacylglycerol kinase family.

31033:LOC101079748
gene id: 31033:LOC101079748
uniprot id: H2TVY7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

31033:LOC101062643
gene id: 31033:LOC101062643
uniprot id: A0A674P7G5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TGF-beta family.
messages: Homodimeric or heterodimeric through association with alpha and beta subunits, linked by one or more disulfide bonds. Inhibins are heterodimers of one alpha and one beta subunit. Activins are homo- or heterodimers of beta subunits only.
messages: Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins.
messages: Secreted

31033:kif3c
gene id: 31033:kif3c
uniprot id: H2RWI7
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

31033:ppp4c
gene id: 31033:ppp4c
uniprot id: H2TWI2
names: Similarity
messages: Belongs to the PPP phosphatase family.

31033:LOC101065694
gene id: 31033:LOC101065694
uniprot id: A0A3B5KG77
names: Similarity
messages: Belongs to the PROTOR family.

31033:timm13
gene id: 31033:timm13
uniprot id: A0A674PI64
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the small Tim family.
messages: Heterohexamer.
messages: Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.
messages: Mitochondrion inner membrane
messages: The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space.

31033:LOC101073522
gene id: 31033:LOC101073522
uniprot id: A0A674NEF8
uniprot id: A0A674PPQ0
names: Similarity
messages: Belongs to the DOCK family.

31033:doc2b
gene id: 31033:doc2b
uniprot id: A0A674PCX8
names: Subcellular Location Annotation
messages: Membrane

31033:ppip5k1
gene id: 31033:ppip5k1
uniprot id: H2U8Z3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histidine acid phosphatase family. VIP1 subfamily.
messages: Bifunctional inositol kinase that acts in concert with the IP6K kinases to synthesize the diphosphate group-containing inositol pyrophosphates diphosphoinositol pentakisphosphate, PP-InsP5, and bis-diphosphoinositol tetrakisphosphate, (PP)2-InsP4. PP-InsP5 and (PP)2-InsP4, also respectively called InsP7 and InsP8, may regulate a variety of cellular processes, including apoptosis, vesicle trafficking, cytoskeletal dynamics, and exocytosis. Phosphorylates inositol hexakisphosphate (InsP6).
messages: cytosol

31033:LOC101071804
gene id: 31033:LOC101071804
uniprot id: H2TV99
names: Subcellular Location Annotation
messages: Nucleus speckle

31033:slc25a16
gene id: 31033:slc25a16
uniprot id: H2UD72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

31033:plekha8
gene id: 31033:plekha8
uniprot id: A0A674PEL3
names: Subcellular Location Annotation
messages: Membrane
messages: trans-Golgi network membrane

31033:atg9a
gene id: 31033:atg9a
uniprot id: Q3T8Y8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATG9 family.
messages: Membrane
messages: Phospholipid scramblase involved in autophagy. Cycles between the preautophagosomal structure/phagophore assembly site (PAS) and the cytoplasmic vesicle pool and supplies membrane for the growing autophagosome. Lipid scramblase activity plays a key role in preautophagosomal structure/phagophore assembly by distributing the phospholipids that arrive through ATG2 from the cytoplasmic to the luminal leaflet of the bilayer, thereby driving autophagosomal membrane expansion.
messages: Preautophagosomal structure membrane

31033:LOC101077340
gene id: 31033:LOC101077340
uniprot id: A0A674MZ71
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

31033:brcc3
gene id: 31033:brcc3
uniprot id: H2S9G6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase M67A family. BRCC36 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Component of the BRCA1-A complex. Component of the BRISC complex. Both the BRCA1-A complex and the BRISC complex bind polyubiquitin.
messages: Cytoplasm
messages: Metalloprotease that specifically cleaves 'Lys-63'-linked polyubiquitin chains. Component of the BRCA1-A complex, a complex that specifically recognizes 'Lys-63'-linked ubiquitinated histones H2A and H2AX at DNA lesions sites, leading to target the brca1-bard1 heterodimer to sites of DNA damage at double-strand breaks (DSBs). Catalytic subunit of the BRISC complex, a multiprotein complex that specifically cleaves 'Lys-63'-linked ubiquitin in various substrates. Mediates the specific 'Lys-63'-specific deubiquitination associated with the COP9 signalosome complex (CSN), via the interaction of the BRISC complex with the CSN complex. The BRISC complex is required for normal mitotic spindle assembly and microtubule attachment to kinetochores via its role in deubiquitinating NUMA1.
messages: Nucleus
messages: spindle pole

31033:stxbp2
gene id: 31033:stxbp2
uniprot id: H2UMA3
names: Similarity
messages: Belongs to the STXBP/unc-18/SEC1 family.

31033:LOC101070190
gene id: 31033:LOC101070190
uniprot id: A0A674P5Z6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.
messages: Cytoplasm
messages: Responds to activation by environmental stress and pro-inflammatory cytokines by phosphorylating a number of transcription factors, and thus regulates transcriptional activity.

31033:rngtt
gene id: 31033:rngtt
uniprot id: A0A674PMV5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bifunctional mRNA-capping enzyme exhibiting RNA 5'-triphosphate monophosphatase activity in the N-terminal part and mRNA guanylyltransferase activity in the C-terminal part. Catalyzes the first two steps of cap formation: by removing the gamma-phosphate from the 5'-triphosphate end of nascent mRNA to yield a diphosphate end, and by transferring the GMP moiety of GTP to the 5'-diphosphate terminus of RNA via a covalent enzyme-GMP reaction intermediate.
messages: In the C-terminal section; belongs to the eukaryotic GTase family.
messages: In the N-terminal section; belongs to the non-receptor class of the protein-tyrosine phosphatase family.
messages: Nucleus

31033:ndufa11
gene id: 31033:ndufa11
uniprot id: A0A3B5JW85
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I NDUFA11 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

31033:nit1
gene id: 31033:nit1
uniprot id: H2SD88
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

31033:LOC101074181
gene id: 31033:LOC101074181
uniprot id: A0A3B5KCR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

31033:hoxd11
gene id: 31033:hoxd11
uniprot id: I6L704
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

31033:LOC101076158
gene id: 31033:LOC101076158
uniprot id: A0A3B5JZR6
names: Function
names: Similarity
messages: Belongs to the calponin family.
messages: Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity.

31033:slc44a2
gene id: 31033:slc44a2
uniprot id: A0A674MGG9
uniprot id: H2T9M3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CTL (choline transporter-like) family.
messages: Membrane

31033:rps15
gene id: 31033:rps15
uniprot id: A0A674PMU0
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.

31033:grpr
gene id: 31033:grpr
uniprot id: H2V352
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

31033:senp8
gene id: 31033:senp8
uniprot id: H2UYZ1
names: Similarity
messages: Belongs to the peptidase C48 family.

31033:txnl4b
gene id: 31033:txnl4b
uniprot id: A0A674NNA5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DIM1 family.
messages: Nucleus
messages: Plays role in pre-mRNA splicing.

31033:tbl1xr1
gene id: 31033:tbl1xr1
uniprot id: A0A3B5K5P0
names: Similarity
messages: Belongs to the WD repeat EBI family.

31033:LOC105416804
gene id: 31033:LOC105416804
uniprot id: Q6E5S1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

31033:LOC101077821
gene id: 31033:LOC101077821
uniprot id: A0A3B5K9J7
names: Subcellular Location Annotation
messages: Membrane

31033:hadha
gene id: 31033:hadha
uniprot id: H2TST0
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.

31033:LOC101065477
gene id: 31033:LOC101065477
uniprot id: A0A3B5KHB5
names: Similarity
messages: Belongs to the SPSB family.

31033:LOC101069596
gene id: 31033:LOC101069596
uniprot id: A0A3B5KGV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ASF1 family.
messages: Nucleus

31033:sox11
gene id: 31033:sox11
uniprot id: Q6WNT4
names: Subcellular Location Annotation
messages: Nucleus

31033:nsdhl
gene id: 31033:nsdhl
uniprot id: H2TFD0
names: Similarity
messages: Belongs to the 3-beta-HSD family.

31033:dars
gene id: 31033:dars
uniprot id: A0A674NKB2
names: Function
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 2 subfamily.
messages: Catalyzes the specific attachment of an amino acid to its cognate tRNA in a 2 step reaction: the amino acid (AA) is first activated by ATP to form AA-AMP and then transferred to the acceptor end of the tRNA.

31033:bmpr1b
gene id: 31033:bmpr1b
uniprot id: H2S1K9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane

31033:LOC101077303
gene id: 31033:LOC101077303
uniprot id: H2S0V8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase A22A family.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Homodimer.
messages: Membrane
messages: Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors.
messages: The PAL motif is required for normal active site conformation.

31033:LOC101063508
gene id: 31033:LOC101063508
uniprot id: A0A674N148
names: Caution
names: Similarity
messages: Belongs to the ephrin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

31033:IL-12 p40
gene id: 31033:IL-12%20p40
uniprot id: Q7SX69
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IL-12B family.
messages: Heterodimer with IL12A; disulfide-linked. The heterodimer is known as interleukin IL-12.
messages: Secreted

31033:rprd1a
gene id: 31033:rprd1a
uniprot id: H2UH76
names: Similarity
messages: Belongs to the UPF0400 (RTT103) family.

31033:LOC101061875
gene id: 31033:LOC101061875
uniprot id: H2UVC4
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Membrane
messages: Mitochondrion inner membrane
messages: The Rieske protein is a high potential 2Fe-2S protein.

31033:LOC101062398
gene id: 31033:LOC101062398
uniprot id: H2SWJ8
names: Similarity
messages: Belongs to the protein kinase superfamily.

31033:LOC101064528
gene id: 31033:LOC101064528
uniprot id: H2THQ2
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

31033:LOC101062836
gene id: 31033:LOC101062836
uniprot id: H2UWV6
names: Cofactor
names: Similarity
messages: Belongs to the paraoxonase family.
messages: Binds 2 calcium ions per subunit.

31033:leprot
gene id: 31033:leprot
uniprot id: B3Y064
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Tissue Specificity
messages: Belongs to the OB-RGRP/VPS55 family.
messages: Endosome membrane
messages: Golgi apparatus membrane
messages: Involved in protein trafficking. May be involved in the down-regulation of membrane protein levels (By similarity).
messages: Widely expressed.

31033:pde7b
gene id: 31033:pde7b
uniprot id: A0A3B5K6V0
uniprot id: H2UVS1
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

31033:LOC101069787
gene id: 31033:LOC101069787
uniprot id: H2TUN0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Engrailed homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

31033:smad1
gene id: 31033:smad1
uniprot id: H2UI95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dwarfin/SMAD family.
messages: Cytoplasm
messages: Nucleus

31033:ipo4
gene id: 31033:ipo4
uniprot id: A0A674NAB2
names: Subcellular Location Annotation
messages: Cytoplasm

31033:LOC101072519
gene id: 31033:LOC101072519
uniprot id: A0A674PIA5
names: Subcellular Location Annotation
messages: Nucleus

31033:ube2h
gene id: 31033:ube2h
uniprot id: H2UW20
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

31033:uii
gene id: 31033:uii
uniprot id: Q2L4C0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urotensin-2 family.
messages: Secreted

31033:wsb1
gene id: 31033:wsb1
uniprot id: Q9W5Z5
names: Domain
names: Function
names: Subunit
messages: Component of a probable ECS E3 ubiquitin-protein ligase complex that contains the Elongin BC complex.
messages: Probable substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
messages: The SOCS box domain mediates the interaction with the Elongin BC complex, an adapter module in different E3 ubiquitin ligase complexes.

31033:LOC101061420
gene id: 31033:LOC101061420
uniprot id: A0A674NBR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tumor necrosis factor family.
messages: Membrane
messages: Secreted

31033:slc16a7
gene id: 31033:slc16a7
uniprot id: A0A3B5KBP3
names: Similarity
names: Subcellular Location Annotation
messages: Basolateral cell membrane
messages: Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.
messages: Cytoplasm
messages: Membrane

31033:LOC101067686
gene id: 31033:LOC101067686
uniprot id: H2STK7
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

31033:p2rx1
gene id: 31033:p2rx1
uniprot id: A0A674NL41
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the P2X receptor family.
messages: Functional P2XRs are organized as homomeric and heteromeric trimers.
messages: Membrane
messages: Receptor for ATP that acts as a ligand-gated ion channel.

31033:LOC101075537
gene id: 31033:LOC101075537
uniprot id: H2V3H0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IAP family.
messages: Cytoplasm
messages: Nucleus

31033:LOC101078521
gene id: 31033:LOC101078521
uniprot id: H2SRR0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EMC3 family.
messages: Component of the ER membrane protein complex (EMC).
messages: Membrane

31033:nprl3
gene id: 31033:nprl3
uniprot id: A0A674NCV7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: As a component of the GATOR1 complex functions as an inhibitor of the amino acid-sensing branch of the TORC1 pathway.
messages: Belongs to the NPR3 family.
messages: Lysosome

31033:irx3
gene id: 31033:irx3
uniprot id: A0A3B5KD74
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/IRO homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

31033:LOC101065341
gene id: 31033:LOC101065341
uniprot id: H2TXE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the taffazin family.
messages: Mitochondrion inner membrane
messages: Mitochondrion outer membrane

31033:LOC101066100
gene id: 31033:LOC101066100
uniprot id: H2UIV5
names: Similarity
messages: Belongs to the intermediate filament family.

31033:p2rx7
gene id: 31033:p2rx7
uniprot id: H2TBX6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P2X receptor family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Receptor for ATP that acts as a ligand-gated ion channel.

31033:lipg
gene id: 31033:lipg
uniprot id: H2V0C9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AB hydrolase superfamily. Lipase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

31033:LOC101079195
gene id: 31033:LOC101079195
uniprot id: A0A674NJ66
names: Similarity
messages: Belongs to the small GTPase superfamily. Ras family.

31033:mrpl19
gene id: 31033:mrpl19
uniprot id: H2T062
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.

31033:ddx3x
gene id: 31033:ddx3x
uniprot id: A0A674MFT2
uniprot id: H2UFU0
uniprot id: H2UFU1
names: Similarity
messages: Belongs to the DEAD box helicase family.

31033:cops3
gene id: 31033:cops3
uniprot id: A0A3B5KJ56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSN3 family.
messages: Cytoplasm
messages: Nucleus

31033:LOC101062968
gene id: 31033:LOC101062968
uniprot id: A0A674NKX7
names: Similarity
messages: Belongs to the IFRD family.

31033:egr1
gene id: 31033:egr1
uniprot id: A0A3B5KCH3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EGR C2H2-type zinc-finger protein family.
messages: Nucleus
messages: Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death.

31033:LOC101074968
gene id: 31033:LOC101074968
uniprot id: A0A674N0H8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes medium subunit family.
messages: Golgi apparatus
messages: Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules.
messages: clathrin-coated vesicle membrane

31033:cdc37l1
gene id: 31033:cdc37l1
uniprot id: A0A674P4K1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDC37 family.
messages: Cytoplasm

31033:dtd1
gene id: 31033:dtd1
uniprot id: H2TE46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DTD family.
messages: Cytoplasm

31033:LOC101062487
gene id: 31033:LOC101062487
uniprot id: A0A674MPG6
names: Caution
names: Similarity
messages: Belongs to the thrombospondin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

31033:LOC101079834
gene id: 31033:LOC101079834
uniprot id: A0A3B5JYD4
names: Similarity
messages: Belongs to the CARF family.

31033:LOC101064470
gene id: 31033:LOC101064470
uniprot id: H2TSJ2
names: Similarity
messages: Belongs to the EVA1 family.

31033:fam168b
gene id: 31033:fam168b
uniprot id: H2SWU9
names: Similarity
messages: Belongs to the FAM168 family.

31033:pfdn6
gene id: 31033:pfdn6
uniprot id: H2SAQ1
names: Similarity
messages: Belongs to the prefoldin subunit beta family.

31033:tcea3
gene id: 31033:tcea3
uniprot id: H2UCQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFS-II family.
messages: Necessary for efficient RNA polymerase II transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by S-II allows the resumption of elongation from the new 3'-terminus.
messages: Nucleus

31033:lhfpl6
gene id: 31033:lhfpl6
uniprot id: H2UI19
names: Subcellular Location Annotation
messages: Membrane

31033:chmp6
gene id: 31033:chmp6
uniprot id: A0A3B5K7Y1
names: Similarity
messages: Belongs to the SNF7 family.

31033:rho
gene id: 31033:rho
uniprot id: Q9IAH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
messages: Membrane
messages: photoreceptor outer segment

31033:myd88
gene id: 31033:myd88
uniprot id: A8QMS7
names: Domain
names: Function
names: Subcellular Location Annotation
messages: Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.
messages: Cytoplasm
messages: The intermediate domain (ID) is required for the phosphorylation and activation of IRAK.

31033:gas8
gene id: 31033:gas8
uniprot id: H2TEW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DRC4 family.
messages: flagellum axoneme

31033:iars
gene id: 31033:iars
uniprot id: H2SY46
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

31033:spock3
gene id: 31033:spock3
uniprot id: A0A674NXS1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

31033:LOC101075569
gene id: 31033:LOC101075569
uniprot id: H2RRP3
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cGMP subfamily.

31033:snapc3
gene id: 31033:snapc3
uniprot id: H2TJN2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SNAPC3/SRD2 family.
messages: Nucleus
messages: Part of the SNAPc complex composed of 5 subunits: SNAPC1, SNAPC2, SNAPC3, SNAPC4 and SNAPC5. SNAPC3 interacts with SNAPC1.
messages: Part of the SNAPc complex required for the transcription of both RNA polymerase II and III small-nuclear RNA genes. Binds to the proximal sequence element (PSE), a non-TATA-box basal promoter element common to these 2 types of genes. Recruits TBP and BRF2 to the U6 snRNA TATA box.

31033:coq10b
gene id: 31033:coq10b
uniprot id: H2USC0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the COQ10 family.
messages: Interacts with coenzyme Q.
messages: Required for the function of coenzyme Q in the respiratory chain. May serve as a chaperone or may be involved in the transport of Q6 from its site of synthesis to the catalytic sites of the respiratory complexes.

31033:polr1a
gene id: 31033:polr1a
uniprot id: H2RY49
names: Function
names: Similarity
messages: Belongs to the RNA polymerase beta' chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.

31033:LOC101078733
gene id: 31033:LOC101078733
uniprot id: H2RQ54
names: Similarity
messages: Belongs to the eukaryotic initiation factor 4E family.

31033:LOC101066755
gene id: 31033:LOC101066755
uniprot id: H2SQE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAVIN family.
messages: caveola

31033:il12a
gene id: 31033:il12a
uniprot id: Q7SX81
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IL-6 superfamily.
messages: Heterodimer with IL12B; disulfide-linked. The heterodimer is known as interleukin IL-12.
messages: Secreted

31033:LOC101078091
gene id: 31033:LOC101078091
uniprot id: H2T5Z9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the argonaute family. Ago subfamily.
messages: P-body
messages: Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs.

31033:LOC101072573
gene id: 31033:LOC101072573
uniprot id: H2U601
uniprot id: H2U603
uniprot id: H2U604
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
messages: Cytoplasm

31033:gatm
gene id: 31033:gatm
uniprot id: H2V3R1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the amidinotransferase family.
messages: Catalyzes the biosynthesis of guanidinoacetate, the immediate precursor of creatine.
messages: Homodimer.
messages: Mitochondrion inner membrane

31033:LOC101061919
gene id: 31033:LOC101061919
uniprot id: H2RQB0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family.
messages: Cell membrane
messages: Membrane
messages: Might be involved in growth regulation, and in myelinization in the peripheral nervous system.

31033:nlgn3b
gene id: 31033:nlgn3b
uniprot id: D2X2H0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type-B carboxylesterase/lipase family.
messages: Cell membrane
messages: Membrane

31033:snrnp200
gene id: 31033:snrnp200
uniprot id: H2RSA0
names: Similarity
messages: Belongs to the helicase family. SKI2 subfamily.

31033:cldn33c
gene id: 31033:cldn33c
uniprot id: Q6E5U5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

31033:LOC101071455
gene id: 31033:LOC101071455
uniprot id: H2UI82
names: Subcellular Location Annotation
messages: Cell membrane
messages: Endosome membrane
messages: Membrane
messages: Recycling endosome membrane
messages: cilium membrane

31033:ugcg
gene id: 31033:ugcg
uniprot id: H2T1G9
names: Similarity
messages: Belongs to the glycosyltransferase 2 family.

31033:nkx6-1
gene id: 31033:nkx6-1
uniprot id: A0A674NPW5
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

31033:timm8a
gene id: 31033:timm8a
uniprot id: Q90YI5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the small Tim family.
messages: Heterohexamer; composed of 3 copies of TIMM8A and 3 copies of TIMM13, named soluble 70 kDa complex. Associates with the TIM22 complex, whose core is composed of TIMM22 (By similarity).
messages: Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space. The TIMM8-TIMM13 complex mediates the import of some proteins while the predominant TIMM9-TIMM10 70 kDa complex mediates the import of much more proteins (By similarity).
messages: Mitochondrion inner membrane
messages: The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space. However, during the transit of TIMM8A from cytoplasm into mitochondrion, the Cys residues probably coordinate zinc, thereby preventing folding and allowing its transfer across mitochondrial outer membrane (By similarity).

31033:gtf2h1
gene id: 31033:gtf2h1
uniprot id: H2TDV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFB1 family.
messages: Nucleus

31033:LOC101063219
gene id: 31033:LOC101063219
uniprot id: A0A3B5KW15
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

31033:dvl1
gene id: 31033:dvl1
uniprot id: A0A674PEK1
names: Similarity
messages: Belongs to the DSH family.

31033:LOC105419818
gene id: 31033:LOC105419818
uniprot id: H2RUY8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H4 family.
messages: Chromosome
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

31033:slc35a5
gene id: 31033:slc35a5
uniprot id: H2UIG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide-sugar transporter family. SLC35A subfamily.
messages: Membrane

31033:dhrs3
gene id: 31033:dhrs3
uniprot id: H2SUW1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

31033:LOC101069203
gene id: 31033:LOC101069203
uniprot id: H2UTK4
names: Similarity
messages: Belongs to the FBPase class 1 family.

31033:LOC101070735
gene id: 31033:LOC101070735
uniprot id: Q1KKR6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family. Deformed subfamily.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

31033:LOC101077630
gene id: 31033:LOC101077630
uniprot id: H2UCZ6
names: Similarity
messages: Belongs to the stathmin family.

31033:rgmb
gene id: 31033:rgmb
uniprot id: A0A674NSI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the repulsive guidance molecule (RGM) family.
messages: Cell membrane
messages: Membrane

31033:stk11
gene id: 31033:stk11
uniprot id: H2TJI9
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. LKB1 subfamily.

31033:LOC101062287
gene id: 31033:LOC101062287
uniprot id: A0A674MUI4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

31033:ddx41
gene id: 31033:ddx41
uniprot id: A0A3B5K304
names: Similarity
messages: Belongs to the DEAD box helicase family. DDX41 subfamily.

31033:LOC101073451
gene id: 31033:LOC101073451
uniprot id: H2V196
names: Subcellular Location Annotation
messages: Nucleus

31033:LOC101074401
gene id: 31033:LOC101074401
uniprot id: H2T292
names: Similarity
messages: Belongs to the FAM10 family.

31033:tp73
gene id: 31033:tp73
uniprot id: A0A674N153
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression.
messages: Belongs to the p53 family.
messages: Binds 1 zinc ion per subunit.
messages: Binds DNA as a homotetramer.
messages: Cytoplasm
messages: Nucleus

31033:cacng5
gene id: 31033:cacng5
uniprot id: A0A674MAW0
names: Similarity
messages: Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.

31033:slc5a1
gene id: 31033:slc5a1
uniprot id: A0A674PD87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

31033:LOC101064934
gene id: 31033:LOC101064934
uniprot id: A0A3B5JZ28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylin family.
messages: Secreted

31033:slc25a53
gene id: 31033:slc25a53
uniprot id: H2TM19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

31033:uba3
gene id: 31033:uba3
uniprot id: H2U2Y1
names: Function
names: Similarity
messages: Belongs to the ubiquitin-activating E1 family. UBA3 subfamily.
messages: Catalytic subunit of the dimeric E1 enzyme, which activates NEDD8.

31033:nf2
gene id: 31033:nf2
uniprot id: H2UYK2
names: Subcellular Location Annotation
messages: Membrane
messages: cytoskeleton

31033:LOC101071719
gene id: 31033:LOC101071719
uniprot id: O57656
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm
messages: Has glycerol-3-phosphate dehydrogenase activity.
messages: Homodimer.

31033:esrra
gene id: 31033:esrra
uniprot id: H2RWY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR3 subfamily.
messages: Nucleus

31033:LOC101076059
gene id: 31033:LOC101076059
uniprot id: H2T8S3
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

31033:LOC101067042
gene id: 31033:LOC101067042
uniprot id: A0A3B5JWE9
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

31033:LOC101064386
gene id: 31033:LOC101064386
uniprot id: Q1KKS2
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c family.
messages: Binds 1 heme c group covalently per subunit.
messages: Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain (By similarity).
messages: Mitochondrion intermembrane space

31033:LOC101069891
gene id: 31033:LOC101069891
uniprot id: A0A674PAM9
names: Similarity
messages: Belongs to the PRORSD1 family.

31033:pax1
gene id: 31033:pax1
uniprot id: H2T659
names: Subcellular Location Annotation
messages: Nucleus

31033:gpr119
gene id: 31033:gpr119
uniprot id: Q7T2L4
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

31033:LOC101074017
gene id: 31033:LOC101074017
uniprot id: H2UGI0
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

31033:lnpkb
gene id: 31033:lnpkb
uniprot id: Q1KKR9
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the lunapark family.
messages: Endoplasmic reticulum (ER)-shaping membrane protein that plays a role in determining ER morphology. Involved in the stabilization of nascent three-way ER tubular junctions within the ER network. May also play a role as a curvature-stabilizing protein within three-way ER tubular junction network (By similarity).
messages: Endoplasmic reticulum membrane
messages: Homodimer; homodimerization requires the C4-type zinc finger motif and decreases during mitosis in a phosphorylation-dependent manner.
messages: Phosphorylated. Phosphorylation occurs during interphase. Phosphorylation occurs also during mitosis; these phosphorylations reduce both its homodimerization and the ER three-way tubular junction formation.
messages: The transmembrane domain 1 and 2 function as a signal-anchor and stop-transfer sequence, respectively, generating a double-spanning integral membrane protein with a N- and C-terminal cytoplasmic orientation. Transmembrane domain 1 and 2 are probably sufficient to mediate membrane translocation and topology formation in a N-myristoylation-independent manner. Transmembrane domain 2 is sufficient to block the protein secretion pathway. The two coiled-coil domains are necessary for its endoplasmic reticulum (ER) three-way tubular junction localization. The C4-type zinc finger motif is necessary both for its ER three-way tubular junction localization and formation.

31033:hhex
gene id: 31033:hhex
uniprot id: A0A674PHK2
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

31033:LOC101072579
gene id: 31033:LOC101072579
uniprot id: H2U9V3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

31033:csnk1g1
gene id: 31033:csnk1g1
uniprot id: A0A3B5K9C2
names: Similarity
messages: Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. Casein kinase I subfamily.

31033:onecut2
gene id: 31033:onecut2
uniprot id: H2RNA3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CUT homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

31033:cdk8
gene id: 31033:cdk8
uniprot id: H2SAH6
names: Similarity
messages: Belongs to the protein kinase superfamily.

31033:pitx2
gene id: 31033:pitx2
uniprot id: A0A3B5KCK7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family. Bicoid subfamily.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

31033:ctbp2
gene id: 31033:ctbp2
uniprot id: H2TGD1
uniprot id: H2TGD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Nucleus

31033:LOC101074105
gene id: 31033:LOC101074105
uniprot id: H2T390
names: Similarity
messages: Belongs to the RAMP family.

31033:pnpla4
gene id: 31033:pnpla4
uniprot id: A0A674NSG8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

31033:otx1
gene id: 31033:otx1
uniprot id: H2TT89
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

31033:rftn2
gene id: 31033:rftn2
uniprot id: H2USU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the raftlin family.
messages: Cell membrane
messages: Membrane

31033:wnt5a
gene id: 31033:wnt5a
uniprot id: A0A674P4T6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

31033:LOC101078575
gene id: 31033:LOC101078575
uniprot id: H2TED7
names: Cofactor
messages: Binds 3 Ca(2+) ions per subunit. Two of the Ca(2+) ions are bound to the C2 domain.

31033:LOC101071044
gene id: 31033:LOC101071044
uniprot id: H2UYG0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the fibulin family.
messages: Homomultimerizes and interacts with various extracellular matrix components.
messages: Incorporated into fibronectin-containing matrix fibers. May play a role in cell adhesion and migration along protein fibers within the extracellular matrix (ECM). Could be important for certain developmental processes and contribute to the supramolecular organization of ECM architecture, in particular to those of basement membranes.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

31033:pnmt
gene id: 31033:pnmt
uniprot id: H2U268
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. NNMT/PNMT/TEMT family.

31033:LOC100462937
gene id: 31033:LOC100462937
uniprot id: A0A674PGU8
names: Similarity
messages: Belongs to the aldolase class II family. Adducin subfamily.

31033:gpr39
gene id: 31033:gpr39
uniprot id: A7UKT2
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

31033:LOC101079597
gene id: 31033:LOC101079597
uniprot id: H2UX11
names: Similarity
messages: Belongs to the CD225/Dispanin family.

31033:tex261
gene id: 31033:tex261
uniprot id: A0A3B5JXT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SVP26 family.
messages: Membrane

31033:cacnb2
gene id: 31033:cacnb2
uniprot id: A0A3B5KGS5
uniprot id: H2UYV1
names: Function
names: Similarity
messages: Belongs to the calcium channel beta subunit family.
messages: The beta subunit of voltage-dependent calcium channels contributes to the function of the calcium channel by increasing peak calcium current, shifting the voltage dependencies of activation and inactivation, modulating G protein inhibition and controlling the alpha-1 subunit membrane targeting.

31033:htr1a-b
gene id: 31033:htr1a-b
uniprot id: O42384
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. 5-hydroxytryptamine receptor subfamily.
messages: Cell membrane
messages: G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various drugs and psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Beta-arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways. Signaling inhibits adenylate cyclase activity and activates a phosphatidylinositol-calcium second messenger system that regulates the release of Ca(2+) ions from intracellular stores. Plays a role in the regulation of 5-hydroxytryptamine release and in the regulation of dopamine and 5-hydroxytryptamine metabolism. Plays a role in the regulation of dopamine and 5-hydroxytryptamine levels in the brain, and thereby affects neural activity and behavior (By similarity).

31033:LOC101065303
gene id: 31033:LOC101065303
uniprot id: H2TG29
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

31033:mtfr1l
gene id: 31033:mtfr1l
uniprot id: H2T599
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MTFR1 family.
messages: Mitochondrion
messages: Plays a role in mitochondrial aerobic respiration. Regulates mitochondrial organization and fission.

31033:LOC105418153
gene id: 31033:LOC105418153
uniprot id: H2THS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

31033:rragc
gene id: 31033:rragc
uniprot id: H2TEY5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTR/RAG GTP-binding protein family.
messages: Cytoplasm
messages: Guanine nucleotide-binding protein that plays a crucial role in the cellular response to amino acid availability through regulation of the mTORC1 signaling cascade.
messages: Lysosome

31033:LOC101064170
gene id: 31033:LOC101064170
uniprot id: H2SQR6
names: Similarity
messages: Belongs to the intermediate filament family.

31033:wdr4
gene id: 31033:wdr4
uniprot id: H2RYB5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat TRM82 family.
messages: Forms a heterodimer with the catalytic subunit METTL1.
messages: Nucleus
messages: Required for the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. In the complex, it is required to stabilize and induce conformational changes of the catalytic subunit.

31033:panx3
gene id: 31033:panx3
uniprot id: H2S112
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pannexin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Structural component of the gap junctions and the hemichannels.
messages: gap junction

31033:degs2
gene id: 31033:degs2
uniprot id: A0A674NN05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase type 1 family. DEGS subfamily.
messages: Endoplasmic reticulum membrane
messages: Membrane

31033:slc22a18
gene id: 31033:slc22a18
uniprot id: A0A3B5K724
names: Subcellular Location Annotation
messages: Membrane

31033:LOC101077910
gene id: 31033:LOC101077910
uniprot id: H2S7R5
names: Subcellular Location Annotation
messages: extracellular space

31033:LOC101069969
gene id: 31033:LOC101069969
uniprot id: H2SYB4
names: Similarity
messages: In the N-terminal section; belongs to the AlaDH/PNT family.

31033:LOC101064958
gene id: 31033:LOC101064958
uniprot id: A0A3B5KQI3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

31033:tbpl1
gene id: 31033:tbpl1
uniprot id: A6H915
names: Similarity
messages: Belongs to the TBP family.

31033:nptn
gene id: 31033:nptn
uniprot id: A0A674N004
names: Subcellular Location Annotation
messages: Membrane

31033:ppil6
gene id: 31033:ppil6
uniprot id: H2TCH8
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

31033:htt
gene id: 31033:htt
uniprot id: A0A674MJN0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the huntingtin family.
messages: Cytoplasm
messages: May play a role in microtubule-mediated transport or vesicle function.
messages: Nucleus

31033:ugt8
gene id: 31033:ugt8
uniprot id: A0A674MHY8
names: Similarity
messages: Belongs to the UDP-glycosyltransferase family.

31033:pdcd5
gene id: 31033:pdcd5
uniprot id: A0A3B5JZD0
names: Similarity
messages: Belongs to the PDCD5 family.

31033:LOC101079321
gene id: 31033:LOC101079321
uniprot id: H2SG13
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: Nucleus
messages: Perikaryon
messages: dendrite

31033:fes
gene id: 31033:fes
uniprot id: H2VAN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily.
messages: cytoskeleton

31033:pde8a
gene id: 31033:pde8a
uniprot id: H2V3Q8
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family. PDE8 subfamily.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

31033:slc27a1
gene id: 31033:slc27a1
uniprot id: A0A3B5K661
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

31033:LOC101075923
gene id: 31033:LOC101075923
uniprot id: A0A3B5KBV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the potassium channel family. A (Shaker) (TC 1.A.1.2) subfamily. Kv1.2/KCNA2 sub-subfamily.
messages: Cell membrane
messages: Membrane

31033:LOC101065232
gene id: 31033:LOC101065232
uniprot id: H2T7H4
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Mitochondrion membrane

31033:paqr3
gene id: 31033:paqr3
uniprot id: H2RT57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

31033:hibch
gene id: 31033:hibch
uniprot id: H2U7H8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite. Has high activity toward isobutyryl-CoA. Could be an isobutyryl-CoA dehydrogenase that functions in valine catabolism. Also hydrolyzes 3-hydroxypropanoyl-CoA.
messages: Mitochondrion

31033:slc2a2
gene id: 31033:slc2a2
uniprot id: A0A674PK33
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

31033:LOC101074584
gene id: 31033:LOC101074584
uniprot id: H2U981
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TGF-beta family.
messages: Homodimer; disulfide-linked.
messages: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-2 (TGF-beta-2) chains, which constitute the regulatory and active subunit of TGF-beta-2, respectively.
messages: extracellular matrix

31033:mthfd1
gene id: 31033:mthfd1
uniprot id: H2U4F9
names: Similarity
names: Subunit
messages: Homodimer.
messages: In the C-terminal section; belongs to the formate--tetrahydrofolate ligase family.
messages: In the N-terminal section; belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.

31033:syp
gene id: 31033:syp
uniprot id: H2RVX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptophysin/synaptobrevin family.
messages: Membrane

31033:kcnj8
gene id: 31033:kcnj8
uniprot id: H2TK24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Membrane

31033:LOC101069157
gene id: 31033:LOC101069157
uniprot id: A0A3B5KBK5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.

31033:tas1r2b
gene id: 31033:tas1r2b
uniprot id: Q2MHJ9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

31033:snx33
gene id: 31033:snx33
uniprot id: H2UW34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Cytoplasmic vesicle membrane

31033:ppil4
gene id: 31033:ppil4
uniprot id: H2SVG0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cyclophilin-type PPIase family. PPIL4 subfamily.
messages: Nucleus
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

31033:ercc2
gene id: 31033:ercc2
uniprot id: H2T012
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the helicase family. RAD3/XPD subfamily.
messages: Nucleus

31033:vps4b
gene id: 31033:vps4b
uniprot id: A0A3B5K431
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: Late endosome membrane

31033:LOC101063915
gene id: 31033:LOC101063915
uniprot id: A0A674NQM9
uniprot id: H2TT26
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family. PDE4 subfamily.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

31033:lrrc42
gene id: 31033:lrrc42
uniprot id: A0A3B5KLZ3
names: Similarity
messages: Belongs to the LRRC42 family.

31033:LOC101073863
gene id: 31033:LOC101073863
uniprot id: A0A3B5KPW6
names: Similarity
messages: Belongs to the WD repeat CDC20/Fizzy family.

31033:kcnj3
gene id: 31033:kcnj3
uniprot id: H2T1X0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with GIRK2, GIRK3 or GIRK4 to form a G-protein activated heteromultimer pore-forming unit. The resulting inward current is much larger.
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family. KCNJ3 subfamily.
messages: Membrane
messages: This potassium channel is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. This receptor plays a crucial role in regulating the heartbeat.

31033:LOC101076201
gene id: 31033:LOC101076201
uniprot id: H2SQW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM IMP/VICKZ family.
messages: Cytoplasm
messages: Nucleus

31033:LOC101065122
gene id: 31033:LOC101065122
uniprot id: H2TS63
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

31033:LOC101061342
gene id: 31033:LOC101061342
uniprot id: H2TGH4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

31033:tgfb1i1
gene id: 31033:tgfb1i1
uniprot id: H2SLI5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paxillin family.
messages: Functions as a molecular adapter coordinating multiple protein-protein interactions at the focal adhesion complex and in the nucleus. Links various intracellular signaling modules to plasma membrane receptors and regulates the Wnt and TGFB signaling pathways.
messages: Nucleus matrix
messages: The LD (leucine and aspartate-rich) motif 3 mediates interaction with GIT1 and functions as a nuclear export signal.
messages: cytoskeleton
messages: focal adhesion

31033:lin28b
gene id: 31033:lin28b
uniprot id: A0A674PJA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lin-28 family.
messages: nucleolus

31033:pim3
gene id: 31033:pim3
uniprot id: A0A3B5JXH0
names: Function
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PIM subfamily.
messages: Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation.

31033:fglce
gene id: 31033:fglce
uniprot id: Q2PED6
names: Caution
names: Cofactor
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

31033:LOC101075404
gene id: 31033:LOC101075404
uniprot id: A0A3B5K4R8
names: Subcellular Location Annotation
messages: mitochondrion nucleoid

31033:znf277
gene id: 31033:znf277
uniprot id: H2UJX1
names: Similarity
messages: Belongs to the ZNF277 family.

31033:prkx
gene id: 31033:prkx
uniprot id: A0A3B5K2K9
uniprot id: A0A674NUQ4
names: Similarity
messages: Belongs to the protein kinase superfamily.

31033:LOC101067122
gene id: 31033:LOC101067122
uniprot id: H2UH43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. ADCK protein kinase family.
messages: Membrane
messages: Mitochondrion

31033:ednra
gene id: 31033:ednra
uniprot id: A3KE13
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cell membrane
messages: Interacts with HDAC7 and KAT5.
messages: Membrane
messages: Receptor for endothelin-1. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of binding affinities for ET-A is: ET1 > ET2 >> ET3.

31033:wdr91
gene id: 31033:wdr91
uniprot id: A0A674MX99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat WDR91 family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Late endosome membrane
messages: Membrane

31033:spc24
gene id: 31033:spc24
uniprot id: A0A3B5JY83
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.
messages: Belongs to the SPC24 family.
messages: Component of the NDC80 complex.
messages: Nucleus
messages: kinetochore

31033:spcs1
gene id: 31033:spcs1
uniprot id: A0A674P6L3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPCS1 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

31033:snrpd1
gene id: 31033:snrpd1
uniprot id: H2TD27
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP core protein family.
messages: Nucleus
messages: Plays a role in pre-mRNA splicing as a core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome.

31033:slc41a1
gene id: 31033:slc41a1
uniprot id: A0A6D2Y5J7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Membrane

31033:ccna1
gene id: 31033:ccna1
uniprot id: A0A674ME32
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cyclin family. Cyclin AB subfamily.
messages: Essential for the control of the cell cycle at the G2/M (mitosis) transition.
messages: Interacts with the CDK1 protein kinase to form a serine/threonine kinase holoenzyme complex also known as maturation promoting factor (MPF). The cyclin subunit imparts substrate specificity to the complex.

31033:LOC101066426
gene id: 31033:LOC101066426
uniprot id: H2SJP4
names: Subcellular Location Annotation
messages: Cytoplasm

31033:med7
gene id: 31033:med7
uniprot id: A0A674NSV7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 7 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.
messages: Component of the Mediator complex.
messages: Nucleus

31033:mturn
gene id: 31033:mturn
uniprot id: H2UEE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MTURN family.
messages: Cytoplasm

31033:prpf18
gene id: 31033:prpf18
uniprot id: H2TUW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRP18 family.
messages: Nucleus speckle

31033:frat2
gene id: 31033:frat2
uniprot id: H2RXZ5
names: Similarity
messages: Belongs to the GSK-3-binding protein family.

31033:pdcd10
gene id: 31033:pdcd10
uniprot id: A0A3B5KJ01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PDCD10 family.
messages: Cell membrane
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Membrane

31033:LOC101069140
gene id: 31033:LOC101069140
uniprot id: H2UTU2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aggrecan/versican proteoglycan family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

31033:supt4h1
gene id: 31033:supt4h1
uniprot id: A0A674NYQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPT4 family.
messages: Component of the DRB sensitivity-inducing factor complex (DSIF complex), which regulates transcription elongation by RNA polymerase II.
messages: Nucleus

31033:snrpc
gene id: 31033:snrpc
uniprot id: A0A674NDW4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the U1 small nuclear ribonucleoprotein C family.
messages: Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. SNRPC/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region.
messages: Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. snrpc/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates E complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region.
messages: Nucleus
messages: U1 snRNP is composed of the 7 core Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP, and at least 3 U1 snRNP-specific proteins SNRNP70/U1-70K, SNRPA/U1-A and SNRPC/U1-C. SNRPC/U1-C interacts with U1 snRNA and the 5' splice-site region of the pre-mRNA.

31033:c8g
gene id: 31033:c8g
uniprot id: H2RU50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calycin superfamily. Lipocalin family.
messages: Secreted

31033:sh2b2
gene id: 31033:sh2b2
uniprot id: H2T7N9
names: Similarity
messages: Belongs to the SH2B adapter family.

31033:pank4
gene id: 31033:pank4
uniprot id: A0A674NLL5
names: Similarity
names: Subunit
messages: Belongs to the type II pantothenate kinase family.
messages: Homodimer. Interacts with PKM.
messages: In the N-terminal section; belongs to the type II pantothenate kinase family.

31033:abr
gene id: 31033:abr
uniprot id: H2RQR8
names: Subcellular Location Annotation
messages: Synapse
messages: axon
messages: dendritic spine

31033:LOC101076447
gene id: 31033:LOC101076447
uniprot id: H2TA64
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FIT family. FIT1 subfamily.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May play a role in the formation of lipid droplets (LDs), which are storage organelles at the center of lipid and energy homeostasis. May directly bind to diacylglycerol (DAGs) and triacylglycerol.
messages: Membrane

31033:LOC101077436
gene id: 31033:LOC101077436
uniprot id: H2T248
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bZIP family.
messages: Homodimer; binds DNA as homodimer. Heterodimer; heterodimerizes with other members of ATF family and with JUN family members.
messages: Nucleus
messages: Stress-responsive chromatin regulator that plays a role in various biological processes including innate immunological memory, adipocyte differentiation or telomerase regulation. In absence of stress, contributes to the formation of heterochromatin and heterochromatin-like structure by recruiting histone H3K9 tri- and di-methyltransferases thus silencing the transcription of target genes such as STAT1 in adipocytes, or genes involved in innate immunity in macrophages and adipocytes. Stress induces ATF7 phosphorylation that disrupts interactions with histone methyltransferase and enhances the association with coactivators containing histone acetyltransferase and/or histone demethylase, leading to disruption of the heterochromatin-like structure and subsequently transcriptional activation. In response to TNF-alpha, which is induced by various stresses, phosphorylated ATF7 and telomerase are released from telomeres leading to telomere shortening.

31033:fahd1
gene id: 31033:fahd1
uniprot id: H2SRW8
names: Similarity
messages: Belongs to the FAH family.

31033:dazap2
gene id: 31033:dazap2
uniprot id: Q5QHQ9
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus speckle
messages: nuclear body

31033:ngrn
gene id: 31033:ngrn
uniprot id: H2SAJ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the neugrin family.
messages: Forms a regulatory protein-RNA complex, consisting of RCC1L, NGRN, RPUSD3, RPUSD4, TRUB2, FASTKD2 and 16S mt-rRNA. Interacts with 16S mt-rRNA; this interaction is direct.
messages: Mitochondrion membrane
messages: Plays an essential role in mitochondrial ribosome biogenesis. As a component of a functional protein-RNA module, consisting of RCC1L, NGRN, RPUSD3, RPUSD4, TRUB2, FASTKD2 and 16S mitochondrial ribosomal RNA (16S mt-rRNA), controls 16S mt-rRNA abundance and is required for intra-mitochondrial translation of core subunits of the oxidative phosphorylation system.

31033:chmp4b
gene id: 31033:chmp4b
uniprot id: A0A674MI59
names: Similarity
messages: Belongs to the SNF7 family.

31033:LOC101075520
gene id: 31033:LOC101075520
uniprot id: A0A3B5JY74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

31033:LOC101064158
gene id: 31033:LOC101064158
uniprot id: H2UF93
names: Similarity
messages: Belongs to the MAGUK family.

31033:pmvk
gene id: 31033:pmvk
uniprot id: H2RJ43
names: Subcellular Location Annotation
messages: cytosol

31033:LOC101065009
gene id: 31033:LOC101065009
uniprot id: H2TGP1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

31033:ssu72
gene id: 31033:ssu72
uniprot id: A0A674MLZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SSU72 phosphatase family.
messages: Nucleus
messages: Protein phosphatase that catalyzes the dephosphorylation of the C-terminal domain of RNA polymerase II. Plays a role in RNA processing and termination.

31033:LOC101062951
gene id: 31033:LOC101062951
uniprot id: A0A3B5KLB5
names: Subcellular Location Annotation
messages: Membrane

31033:atg4d
gene id: 31033:atg4d
uniprot id: H2RSB2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C54 family.
messages: Cysteine protease that plays a key role in autophagy by mediating both proteolytic activation and delipidation of ATG8 family proteins.
messages: Cytoplasm

31033:LOC101071730
gene id: 31033:LOC101071730
uniprot id: H2UMW1
names: Subcellular Location Annotation
messages: extracellular space

31033:LOC101080060
gene id: 31033:LOC101080060
uniprot id: A0A674MLX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CART family.
messages: Secreted

31033:nsun2
gene id: 31033:nsun2
uniprot id: H2TYJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: extracellular exosome

31033:nudt19
gene id: 31033:nudt19
uniprot id: H2RKH3
names: Similarity
messages: Belongs to the Nudix hydrolase family.

31033:LOC101066841
gene id: 31033:LOC101066841
uniprot id: H2TGP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM163 family.
messages: Membrane

31033:LOC101065277
gene id: 31033:LOC101065277
uniprot id: H2UT58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transcription factor STAT family.
messages: Cytoplasm
messages: Nucleus

31033:LOC101061332
gene id: 31033:LOC101061332
uniprot id: A0A674PLX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the poly(A) polymerase family.
messages: Nucleus

31033:LOC101063355
gene id: 31033:LOC101063355
uniprot id: H2SUC4
names: Similarity
messages: Belongs to the PP2C family.

31033:LOC101063586
gene id: 31033:LOC101063586
uniprot id: H2SXF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

31033:cdk9
gene id: 31033:cdk9
uniprot id: H2TD26
names: Similarity
messages: Belongs to the protein kinase superfamily.

31033:LOC101074197
gene id: 31033:LOC101074197
uniprot id: A0A674MRB8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glypican family.
messages: Cell membrane
messages: Cell surface proteoglycan that bears heparan sulfate.

31033:fgc6ast1
gene id: 31033:fgc6ast1
uniprot id: Q14TH3
names: Caution
names: Cofactor
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

31033:pkp4
gene id: 31033:pkp4
uniprot id: H2STJ6
names: Similarity
messages: Belongs to the beta-catenin family.

31033:ndufb7
gene id: 31033:ndufb7
uniprot id: H2SEJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFB7 subunit family.
messages: Membrane
messages: Mitochondrion inner membrane
messages: Mitochondrion intermembrane space

31033:LOC101076515
gene id: 31033:LOC101076515
uniprot id: H2TH94
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

31033:LOC101071543
gene id: 31033:LOC101071543
uniprot id: H2S9P1
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

31033:trappc2l
gene id: 31033:trappc2l
uniprot id: H2V4Q7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAPP small subunits family. Sedlin subfamily.
messages: perinuclear region

31033:mindy3
gene id: 31033:mindy3
uniprot id: H2U7I8
names: Function
names: Similarity
messages: Belongs to the MINDY deubiquitinase family. FAM188 subfamily.
messages: Hydrolase that can remove 'Lys-48'-linked conjugated ubiquitin from proteins.

31033:LOC101076498
gene id: 31033:LOC101076498
uniprot id: A0A674NIB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

31033:LOC101064109
gene id: 31033:LOC101064109
uniprot id: A0A674P1M7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurexin family.
messages: Belongs to the syndecan proteoglycan family.
messages: Cell surface proteoglycan.
messages: Membrane

31033:tmem167b
gene id: 31033:tmem167b
uniprot id: A0A3B5KFA6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KISH family.
messages: Golgi apparatus membrane
messages: Involved in the early part of the secretory pathway.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

31033:anapc5
gene id: 31033:anapc5
uniprot id: H2UXX4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the APC5 family.
messages: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.
messages: spindle

31033:LOC101068421
gene id: 31033:LOC101068421
uniprot id: H2UDA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromogranin/secretogranin protein family.
messages: Secreted

31033:srp72
gene id: 31033:srp72
uniprot id: H2TJ53
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SRP72 family.
messages: Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER).
messages: Cytoplasm

31033:LOC101078447
gene id: 31033:LOC101078447
uniprot id: A0A674MY27
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the APP family.
messages: Cell membrane
messages: Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

31033:nox1
gene id: 31033:nox1
uniprot id: A7E3K6
names: Subcellular Location Annotation
messages: Membrane

31033:mcm7
gene id: 31033:mcm7
uniprot id: H2UJM4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.
messages: Belongs to the MCM family.
messages: Chromosome
messages: Nucleus

31033:LOC101069334
gene id: 31033:LOC101069334
uniprot id: H2T288
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

31033:ovca2
gene id: 31033:ovca2
uniprot id: A0A674PG14
names: Similarity
messages: Belongs to the LovG family.

31033:penk
gene id: 31033:penk
uniprot id: H2TMB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the opioid neuropeptide precursor family.
messages: Secreted

31033:utp3
gene id: 31033:utp3
uniprot id: H2UK14
names: Similarity
messages: Belongs to the SAS10 family.

31033:prr15l
gene id: 31033:prr15l
uniprot id: Q1KKW2
names: Similarity
messages: Belongs to the PRR15 family.

31033:plcg1
gene id: 31033:plcg1
uniprot id: A0A674MB78
names: Function
messages: Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.

31033:LOC101061903
gene id: 31033:LOC101061903
uniprot id: H2TM50
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

31033:LOC101073898
gene id: 31033:LOC101073898
uniprot id: A0A3B5K5K1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LEAP2 family.
messages: Has an antimicrobial activity.
messages: Secreted

31033:LOC101071548
gene id: 31033:LOC101071548
uniprot id: A0A3B5K557
names: Subcellular Location Annotation
messages: Membrane

31033:zdhhc18
gene id: 31033:zdhhc18
uniprot id: H2UC29
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

31033:LOC446001
gene id: 31033:LOC446001
uniprot id: Q7T1U3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMC family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

31033:frk
gene id: 31033:frk
uniprot id: H2SSY6
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

31033:map1lc3c
gene id: 31033:map1lc3c
uniprot id: A0A674MLR2
names: Similarity
messages: Belongs to the ATG8 family.

31033:LOC101074159
gene id: 31033:LOC101074159
uniprot id: H2T1J4
names: Similarity
messages: Belongs to the copine family.

31033:LOC101070320
gene id: 31033:LOC101070320
uniprot id: H2V078
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

31033:LOC101072159
gene id: 31033:LOC101072159
uniprot id: A0A3B5JY15
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Cytoplasm
messages: Homodimer and heterodimer with SSTR3 and SSTR5. Heterodimerization with SSTR3 inactivates SSTR3 receptor function. Heterodimerization with SSTR5 is enhanced by agonist stimulation of SSTR2 and increases SSTR2 cell growth inhibition activity. Following agonist stimulation, homodimers dissociate into monomers which is required for receptor internalization. Interacts with beta-arrestin; this interaction is necessary for receptor internalization and is destabilized by heterodimerization with SSTR5 which results in increased recycling of SSTR2 to the cell surface. Interacts (via C-terminus) with SHANK1 (via PDZ domain).
messages: Membrane
messages: Receptor for somatostatin-14 and -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase. In addition it stimulates phosphotyrosine phosphatase and PLC via pertussis toxin insensitive as well as sensitive G proteins. Inhibits calcium entry by suppressing voltage-dependent calcium channels. Acts as the functionally dominant somatostatin receptor in pancreatic alpha- and beta-cells where it mediates the inhibitory effect of somatostatin-14 on hormone secretion. Inhibits cell growth through enhancement of MAPK1 and MAPK2 phosphorylation and subsequent up-regulation of CDKN1B. Stimulates neuronal migration and axon outgrowth and may participate in neuron development and maturation during brain development. Mediates negative regulation of insulin receptor signaling through PTPN6. Inactivates SSTR3 receptor function following heterodimerization.

31033:LOC101077609
gene id: 31033:LOC101077609
uniprot id: A0A6E7TWQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: GTP-binding protein involved in protein trafficking; modulates vesicle budding and uncoating within the Golgi apparatus.
messages: Golgi apparatus

31033:LOC101067006
gene id: 31033:LOC101067006
uniprot id: A0A674MUW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A6 subfamily.
messages: Cell membrane
messages: Membrane

31033:clstn3
gene id: 31033:clstn3
uniprot id: A0A674NJM2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Golgi apparatus membrane
messages: Membrane

31033:LOC101073780
gene id: 31033:LOC101073780
uniprot id: H2TEP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. LISCH7 family.
messages: Membrane
messages: tight junction

31033:mettl26
gene id: 31033:mettl26
uniprot id: A0A674MMJ6
names: Similarity
messages: Belongs to the UPF0585 family.

31033:LOC101074542
gene id: 31033:LOC101074542
uniprot id: A0A1Q0XE16
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Cytochromes P450 are a group of heme-thiolate monooxygenases. They oxidize a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Microsome membrane

31033:slc48a1
gene id: 31033:slc48a1
uniprot id: A0A3B5KF02
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HRG family.
messages: Endosome membrane
messages: Heme transporter that regulates intracellular heme availability through the endosomal or lysosomal compartment.
messages: Lysosome membrane
messages: Membrane

31033:gpbp1l1
gene id: 31033:gpbp1l1
uniprot id: H2U1I2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vasculin family.
messages: Nucleus

31033:rad50
gene id: 31033:rad50
uniprot id: H2S8G2
names: Similarity
messages: Belongs to the SMC family. RAD50 subfamily.

31033:LOC101079202
gene id: 31033:LOC101079202
uniprot id: A0A674NGL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GLI C2H2-type zinc-finger protein family.
messages: Nucleus

31033:LOC101078698
gene id: 31033:LOC101078698
uniprot id: Q2PR32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

31033:LOC101074126
gene id: 31033:LOC101074126
uniprot id: H2UB72
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular space

31033:gba2
gene id: 31033:gba2
uniprot id: H2VAT6
names: Function
names: Similarity
messages: Belongs to the non-lysosomal glucosylceramidase family.
messages: Non-lysosomal glucosylceramidase that catalyzes the hydrolysis of glucosylceramide (GlcCer) to free glucose and ceramide.

31033:cep19
gene id: 31033:cep19
uniprot id: A0A674MNE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CEP19 family.
messages: centriole
messages: cilium basal body
messages: spindle pole

31033:rtn4ip1
gene id: 31033:rtn4ip1
uniprot id: H2S8W8
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.

31033:LOC101066292
gene id: 31033:LOC101066292
uniprot id: A0A3B5KE99
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cAMP subfamily.

31033:LOC101076827
gene id: 31033:LOC101076827
uniprot id: H2UDB2
names: Subcellular Location Annotation
messages: Membrane

31033:gucy1a2
gene id: 31033:gucy1a2
uniprot id: H2T147
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Cytoplasm

31033:cdkl1
gene id: 31033:cdkl1
uniprot id: H2THF7
names: Similarity
messages: Belongs to the protein kinase superfamily.

31033:LOC101079760
gene id: 31033:LOC101079760
uniprot id: H2V8W5
names: Similarity
messages: Belongs to the splicing factor SR family.

31033:LOC101068793
gene id: 31033:LOC101068793
uniprot id: A0A674MHH2
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and transfers it to its substrates.
messages: Nucleus

31033:rapgef2
gene id: 31033:rapgef2
uniprot id: A0A674MWT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RAPGEF2 family.
messages: Cell junction
messages: Endosome
messages: Late endosome
messages: perinuclear region

31033:mkrn1
gene id: 31033:mkrn1
uniprot id: Q5NU14
names: Function
names: Miscellaneous
messages: E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins.
messages: Non-canonical splice acceptor and donor sites.

31033:gcnt3
gene id: 31033:gcnt3
uniprot id: H2TX75
names: Subcellular Location Annotation
messages: Golgi apparatus membrane
messages: Membrane

31033:tubgcp3
gene id: 31033:tubgcp3
uniprot id: H2V5A2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TUBGCP family.
messages: Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome.
messages: centrosome

31033:LOC101062777
gene id: 31033:LOC101062777
uniprot id: H2V2B0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AB hydrolase superfamily. Lipase family.
messages: Secreted

31033:ptp4a1
gene id: 31033:ptp4a1
uniprot id: A0A674NEG1
names: Subcellular Location Annotation
messages: Early endosome
messages: Endosome

31033:mtmr7
gene id: 31033:mtmr7
uniprot id: H2T8F7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.
messages: Cytoplasm

31033:LOC101061869
gene id: 31033:LOC101061869
uniprot id: H2SW28
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pannexin family.
messages: Cell membrane
messages: Membrane
messages: Structural component of the gap junctions and the hemichannels.
messages: gap junction

31033:fcf1
gene id: 31033:fcf1
uniprot id: H2URA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UTP23/FCF1 family. FCF1 subfamily.
messages: nucleolus

31033:ppp2ca
gene id: 31033:ppp2ca
uniprot id: H2T5N4
names: Similarity
messages: Belongs to the PPP phosphatase family.

31033:rnd3
gene id: 31033:rnd3
uniprot id: A0A674NK30
names: Function
messages: Binds GTP but lacks intrinsic GTPase activity and is resistant to Rho-specific GTPase-activating proteins.

31033:hacd2
gene id: 31033:hacd2
uniprot id: A0A3B5KD36
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the very long-chain fatty acids dehydratase HACD family.
messages: Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

31033:fam207a
gene id: 31033:fam207a
uniprot id: A0A3B5KPM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLX9 family.
messages: nucleolus

31033:rtn8
gene id: 31033:rtn8
uniprot id: Q4G5W8
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

31033:LOC101062999
gene id: 31033:LOC101062999
uniprot id: H2V2B9
names: Function
names: Similarity
messages: Belongs to the cytidylyltransferase family.
messages: Catalyzes the key rate-limiting step in the CDP-choline pathway for phosphatidylcholine biosynthesis.

31033:med17
gene id: 31033:med17
uniprot id: H2SCK9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 17 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

31033:LOC101077122
gene id: 31033:LOC101077122
uniprot id: A0A3B5KJ31
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

31033:rcl1
gene id: 31033:rcl1
uniprot id: A0A674PA99
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA 3'-terminal cyclase family. Type 2 subfamily.
messages: Does not have cyclase activity. Plays a role in 40S-ribosomal-subunit biogenesis in the early pre-rRNA processing steps at sites A0, A1 and A2 that are required for proper maturation of the 18S RNA.
messages: nucleolus

31033:LOC101062066
gene id: 31033:LOC101062066
uniprot id: A0A674PKI8
names: Similarity
names: Subunit
messages: Belongs to the CutA family.
messages: Homotrimer.

31033:LOC101066780
gene id: 31033:LOC101066780
uniprot id: A0A674MTR9
names: Similarity
messages: Belongs to the proteasome subunit S9 family.

31033:lsm6
gene id: 31033:lsm6
uniprot id: A0A3B5KKE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP Sm proteins family. SmF/LSm6 subfamily.
messages: Nucleus

31033:LOC101077681
gene id: 31033:LOC101077681
uniprot id: H2S7R5
names: Subcellular Location Annotation
messages: extracellular space

31033:borcs5
gene id: 31033:borcs5
uniprot id: A0A3B5KKS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BORCS5 family.
messages: Lysosome membrane
messages: Membrane

31033:LOC101078557
gene id: 31033:LOC101078557
uniprot id: H2TIU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GGA protein family.
messages: Early endosome membrane
messages: Endosome membrane
messages: trans-Golgi network membrane

31033:ppfia1
gene id: 31033:ppfia1
uniprot id: H2T387
names: Similarity
messages: Belongs to the liprin family. Liprin-alpha subfamily.

31033:cd8beta
gene id: 31033:cd8beta
uniprot id: A7VKB3
names: Subcellular Location Annotation
messages: Membrane

31033:ddx54
gene id: 31033:ddx54
uniprot id: H2UMM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. DDX54/DBP10 subfamily.
messages: nucleolus

31033:LOC101061207
gene id: 31033:LOC101061207
uniprot id: H2UM56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fascin family.
messages: cytoskeleton

31033:LOC101063578
gene id: 31033:LOC101063578
uniprot id: H2T4S6
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

31033:taf10
gene id: 31033:taf10
uniprot id: H2UQS7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF10 family.
messages: Nucleus
messages: The TFIID basal transcription factor complex plays a major role in the initiation of RNA polymerase II (Pol II)-dependent transcription.

31033:LOC101068642
gene id: 31033:LOC101068642
uniprot id: L8AZK3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AB hydrolase superfamily. Lipase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

31033:fut9b
gene id: 31033:fut9b
uniprot id: Q70AH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 10 family.
messages: Golgi stack membrane

31033:tnip2
gene id: 31033:tnip2
uniprot id: H2SYF2
names: Subcellular Location Annotation
messages: Cytoplasm

31033:runx3
gene id: 31033:runx3
uniprot id: A0A9P4
uniprot id: Q642Y1
names: Subcellular Location Annotation
messages: Nucleus

31033:cnot10
gene id: 31033:cnot10
uniprot id: H2SR13
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CNOT10 family.
messages: Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation.
messages: Cytoplasm
messages: Nucleus

31033:chst2
gene id: 31033:chst2
uniprot id: A0A3B5KJW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 1 family. Gal/GlcNAc/GalNAc subfamily.
messages: Membrane

31033:fgf8
gene id: 31033:fgf8
uniprot id: A0A674MAY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heparin-binding growth factors family.
messages: Secreted

31033:LOC101072603
gene id: 31033:LOC101072603
uniprot id: Q1KKW9
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

31033:dohh
gene id: 31033:dohh
uniprot id: H2T0E0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the deoxyhypusine hydroxylase family.
messages: Binds 2 Fe(2+) ions per subunit.
messages: Catalyzes the hydroxylation of the N(6)-(4-aminobutyl)-L-lysine intermediate to form hypusine, an essential post-translational modification only found in mature eIF-5A factor.

31033:ccm2
gene id: 31033:ccm2
uniprot id: H2SK82
names: Similarity
messages: Belongs to the CCM2 family.

31033:LOC101070901
gene id: 31033:LOC101070901
uniprot id: H2U457
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cyclin family. Cyclin AB subfamily.
messages: Belongs to the retinoblastoma protein (RB) family.
messages: Nucleus

31033:LOC101069528
gene id: 31033:LOC101069528
uniprot id: H2T7B2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

31033:eloc
gene id: 31033:eloc
uniprot id: A0A674P5J1
names: Similarity
messages: Belongs to the SKP1 family.

31033:LOC101072941
gene id: 31033:LOC101072941
uniprot id: H2UH85
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POMC family.
messages: Secreted
messages: Stimulates the adrenal glands to release cortisol.

31033:clpp
gene id: 31033:clpp
uniprot id: H2U4U1
names: Similarity
messages: Belongs to the peptidase S14 family.

31033:LOC101066095
gene id: 31033:LOC101066095
uniprot id: H2UC35
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the hedgehog family.
messages: Cell membrane
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Membrane
messages: Multimer.
messages: The C-terminal part of the hedgehog protein precursor displays an autoproteolysis activity that results in the cleavage of the full-length protein into two parts (N-product and C-product). In addition, the C-terminal part displays a cholesterol transferase activity that results by the covalent attachment of a cholesterol moiety to the C-terminal of the newly generated N-product.
messages: The dually lipidated hedgehog protein N-product is a morphogen which is essential for a variety of patterning events during development.

31033:gstk1
gene id: 31033:gstk1
uniprot id: H2ULE4
names: Similarity
messages: Belongs to the GST superfamily. Kappa family.

31033:glyr1
gene id: 31033:glyr1
uniprot id: A0A674M980
uniprot id: A0A674PLI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HIBADH-related family. NP60 subfamily.
messages: Chromosome

31033:LOC101065558
gene id: 31033:LOC101065558
uniprot id: H2VAE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-alpha family. G(12) subfamily.
messages: Membrane

31033:lyz
gene id: 31033:lyz
uniprot id: P61944
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycosyl hydrolase 22 family.
messages: Lysozyme C is capable of both hydrolysis and transglycosylation; it shows also a slight esterase activity. It acts rapidly on both peptide-substituted and unsubstituted peptidoglycan, and slowly on chitin oligosaccharides.
messages: Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents.
messages: Monomer.
messages: Secreted

31033:oaz1b
gene id: 31033:oaz1b
uniprot id: H2UKG0
names: Similarity
messages: Belongs to the ODC antizyme family.

31033:frrunt
gene id: 31033:frrunt
uniprot id: A0A9P7
names: Subcellular Location Annotation
messages: Nucleus

31033:LOC101066771
gene id: 31033:LOC101066771
uniprot id: Q7M570
names: Similarity
messages: Belongs to the intermediate filament family.

31033:LOC101077900
gene id: 31033:LOC101077900
uniprot id: H2RR19
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM134/TMEM230 family.
messages: Early endosome
messages: Endosome
messages: Involved in trafficking and recycling of synaptic vesicles.
messages: Late endosome
messages: Membrane
messages: Recycling endosome
messages: Vesicle
messages: autophagosome
messages: synaptic vesicle
messages: trans-Golgi network

31033:pym1
gene id: 31033:pym1
uniprot id: A0A674NNC8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pym family.
messages: Cytoplasm
messages: Interacts (via N-terminus) with magoh and rbm8a; the interaction is direct. Associates (eIF2A-like region) with the 40S ribosomal subunit and the 48S preinitiation complex.

31033:fam98b
gene id: 31033:fam98b
uniprot id: H2UE24
names: Similarity
messages: Belongs to the FAM98 family.

31033:LOC101079139
gene id: 31033:LOC101079139
uniprot id: H2UQE2
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

31033:napg
gene id: 31033:napg
uniprot id: A0A3B5K9T3
names: Similarity
messages: Belongs to the SNAP family.

31033:hoxc11
gene id: 31033:hoxc11
uniprot id: Q1KKV2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

31033:LOC101072687
gene id: 31033:LOC101072687
uniprot id: A0A3B5KD80
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

31033:ints7
gene id: 31033:ints7
uniprot id: H2VA27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Integrator subunit 7 family.
messages: Nucleus

31033:foxd1
gene id: 31033:foxd1
uniprot id: H2VDS0
names: Subcellular Location Annotation
messages: Nucleus

31033:hdac2
gene id: 31033:hdac2
uniprot id: A0A674PL70
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone deacetylase family. HD Type 1 subfamily.
messages: Histone deacetylase that catalyzes the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.
messages: Nucleus

31033:psmc1
gene id: 31033:psmc1
uniprot id: H2S9Y9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: Cytoplasm
messages: Nucleus

31033:LOC101068531
gene id: 31033:LOC101068531
uniprot id: H2U7W4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

31033:selenok
gene id: 31033:selenok
uniprot id: H2SUL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the selenoprotein K family.
messages: Endoplasmic reticulum membrane

31033:LOC101078603
gene id: 31033:LOC101078603
uniprot id: H2S9M5
names: Similarity
messages: Belongs to the DEAD box helicase family.

31033:sptlc3
gene id: 31033:sptlc3
uniprot id: A0A674MX77
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

31033:mon1a
gene id: 31033:mon1a
uniprot id: Q9YGN1
names: Similarity
messages: Belongs to the MON1/SAND family.

31033:dmrta2
gene id: 31033:dmrta2
uniprot id: Q4AE28
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DMRT family.
messages: May be involved in sexual development.
messages: Nucleus

31033:mrps24
gene id: 31033:mrps24
uniprot id: A0A674MIN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Mitochondrion

31033:psmc3
gene id: 31033:psmc3
uniprot id: H2T0R7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: Cytoplasm
messages: Nucleus

31033:tmem165
gene id: 31033:tmem165
uniprot id: H2URJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDT1 family.
messages: Membrane

31033:tmem45b
gene id: 31033:tmem45b
uniprot id: H2V2U7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM45 family.
messages: Membrane

31033:LOC101067589
gene id: 31033:LOC101067589
uniprot id: H2S936
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class V-like SAM-binding methyltransferase superfamily. SETD3 actin-histidine methyltransferase family.
messages: Cytoplasm

31033:LOC101069446
gene id: 31033:LOC101069446
uniprot id: H2UKI9
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

31033:elovl6
gene id: 31033:elovl6
uniprot id: A0A674P5X7
names: Caution
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELO family. ELOVL6 subfamily.
messages: Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that elongates fatty acids with 12, 14 and 16 carbons with higher activity toward C16:0 acyl-CoAs. Catalyzes the synthesis of unsaturated C16 long chain fatty acids and, to a lesser extent, C18:0 and those with low desaturation degree. May participate to the production of saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: N-Glycosylated.
messages: The C-terminal di-lysine motif may confer endoplasmic reticulum localization.

31033:LOC101071974
gene id: 31033:LOC101071974
uniprot id: A0A674NV17
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.

31033:LOC101062484
gene id: 31033:LOC101062484
uniprot id: H2TLU1
names: Similarity
messages: Belongs to the SLAIN motif-containing family.

31033:LOC105417853
gene id: 31033:LOC105417853
uniprot id: H2TFB9
names: Similarity
messages: Belongs to the protein phosphatase inhibitor 1 family.

31033:cenpm
gene id: 31033:cenpm
uniprot id: H2RIX7
names: Subcellular Location Annotation
messages: Nucleus

31033:LOC101075116
gene id: 31033:LOC101075116
uniprot id: A0A674MK96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lin-28 family.
messages: nucleolus

31033:LOC101067398
gene id: 31033:LOC101067398
uniprot id: H2U4T1
names: Similarity
messages: Belongs to the MIF family.

31033:parp1
gene id: 31033:parp1
uniprot id: H2UJE1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ARTD/PARP family.
messages: Chromosome
messages: Nucleus
messages: Poly-ADP-ribosyltransferase that mediates poly-ADP-ribosylation of proteins and plays a key role in DNA repair.

31033:lamtor2
gene id: 31033:lamtor2
uniprot id: A0A674N2R1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GAMAD family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane

31033:zdhhc13
gene id: 31033:zdhhc13
uniprot id: H2UT65
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family. AKR/ZDHHC17 subfamily.
messages: Cytoplasmic vesicle membrane
messages: Golgi apparatus membrane
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

31033:supt3h
gene id: 31033:supt3h
uniprot id: H2SSR2
names: Subcellular Location Annotation
messages: Nucleus

31033:usp48
gene id: 31033:usp48
uniprot id: H2RKE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C19 family.
messages: Nucleus

31033:wdpcp
gene id: 31033:wdpcp
uniprot id: H2TTM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat fritz family.
messages: Cell membrane
messages: Membrane
messages: cilium axoneme

31033:mrpl53
gene id: 31033:mrpl53
uniprot id: H2UKG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL53 family.
messages: Mitochondrion

31033:LOC101062935
gene id: 31033:LOC101062935
uniprot id: A0A674NTM6
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cAMP subfamily.

31033:cldn27a
gene id: 31033:cldn27a
uniprot id: Q6E5Q6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: tight junction

31033:LOC101070422
gene id: 31033:LOC101070422
uniprot id: A0A674NL71
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

31033:cyfip1
gene id: 31033:cyfip1
uniprot id: H2TIQ5
names: Similarity
messages: Belongs to the CYFIP family.

31033:pskh1
gene id: 31033:pskh1
uniprot id: A0A674P795
names: Similarity
messages: Belongs to the protein kinase superfamily.

31033:tpk1
gene id: 31033:tpk1
uniprot id: H2RLL1
names: Similarity
messages: Belongs to the thiamine pyrophosphokinase family.

31033:tacr3b
gene id: 31033:tacr3b
uniprot id: A0A6D2WUF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

31033:mrps21
gene id: 31033:mrps21
uniprot id: A0A3B5K0G8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

31033:LOC101061645
gene id: 31033:LOC101061645
uniprot id: H2TDB1
names: Function
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

31033:slc12a1
gene id: 31033:slc12a1
uniprot id: A0A674NVT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC12A transporter family.
messages: Cell membrane
messages: Membrane

31033:igsf3
gene id: 31033:igsf3
uniprot id: H2TPT2
names: Subcellular Location Annotation
messages: Membrane

31033:sfrp2
gene id: 31033:sfrp2
uniprot id: A0A674MHV1
names: Caution
names: Similarity
messages: Belongs to the secreted frizzled-related protein (sFRP) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

31033:LOC101072411
gene id: 31033:LOC101072411
uniprot id: H2SJG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

31033:syf2
gene id: 31033:syf2
uniprot id: H2RTI5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SYF2 family.
messages: Involved in pre-mRNA splicing.
messages: May be part of a spliceosome complex.
messages: Nucleus

31033:brk1
gene id: 31033:brk1
uniprot id: H2T7T4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BRK1 family.
messages: cytoskeleton

31033:scube3
gene id: 31033:scube3
uniprot id: A0A674NE56
uniprot id: H2TMZ1
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

31033:LOC101074529
gene id: 31033:LOC101074529
uniprot id: A0A3B5KGH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

31033:LOC101075233
gene id: 31033:LOC101075233
uniprot id: H2SS84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the parvin family.
messages: cytoskeleton

31033:slc6a17
gene id: 31033:slc6a17
uniprot id: H2S489
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

31033:faxc
gene id: 31033:faxc
uniprot id: H2RK94
names: Similarity
messages: Belongs to the FAX family.

31033:kmt5b
gene id: 31033:kmt5b
uniprot id: A0A3B5KSP4
names: Subcellular Location Annotation
messages: Chromosome
messages: Nucleus

31033:LOC101071060
gene id: 31033:LOC101071060
uniprot id: H2T2C5
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.

31033:LOC101066257
gene id: 31033:LOC101066257
uniprot id: H2UVE4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERD2 family.
messages: COPI-coated vesicle membrane
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

31033:LOC101063304
gene id: 31033:LOC101063304
uniprot id: H2VDW0
names: Subcellular Location Annotation
messages: Membrane

31033:LOC101075603
gene id: 31033:LOC101075603
uniprot id: A0A674NVI2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglutaminase-like superfamily. PNGase family.
messages: Cytoplasm
messages: Specifically deglycosylates the denatured form of N-linked glycoproteins in the cytoplasm and assists their proteasome-mediated degradation. Cleaves the beta-aspartyl-glucosamine (GlcNAc) of the glycan and the amide side chain of Asn, converting Asn to Asp. Prefers proteins containing high-mannose over those bearing complex type oligosaccharides. Can recognize misfolded proteins in the endoplasmic reticulum that are exported to the cytosol to be destroyed and deglycosylate them, while it has no activity toward native proteins. Deglycosylation is a prerequisite for subsequent proteasome-mediated degradation of some, but not all, misfolded glycoproteins.

31033:LOC101063828
gene id: 31033:LOC101063828
uniprot id: A0A674NXK7
names: Similarity
messages: Belongs to the adaptor complexes medium subunit family.

31033:nsa2
gene id: 31033:nsa2
uniprot id: A0A674P4V0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS8 family. Ribosome biogenesis protein NSA2 subfamily.
messages: Component of the pre-66S ribosomal particle.
messages: Involved in the biogenesis of the 60S ribosomal subunit. May play a part in the quality control of pre-60S particles.
messages: nucleolus

31033:cd74
gene id: 31033:cd74
uniprot id: H2SNE4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

31033:LOC101076986
gene id: 31033:LOC101076986
uniprot id: H2UZE9
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family. Prx6 subfamily.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.

31033:tpm3
gene id: 31033:tpm3
uniprot id: Q805C6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tropomyosin family.
messages: cytoskeleton

31033:LOC101067942
gene id: 31033:LOC101067942
uniprot id: A0A674NPC9
names: Similarity
messages: Belongs to the universal ribosomal protein uL24 family.

31033:spry1
gene id: 31033:spry1
uniprot id: A0A3B5K761
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sprouty family.
messages: Cytoplasm
messages: Membrane

31033:wdfy1
gene id: 31033:wdfy1
uniprot id: H2TMU4
names: Subcellular Location Annotation
messages: Early endosome
messages: Endosome

31033:spag9
gene id: 31033:spag9
uniprot id: H2S7N4
names: Similarity
messages: Belongs to the JIP scaffold family.

31033:LOC101079269
gene id: 31033:LOC101079269
uniprot id: Q2PR24
names: Subcellular Location Annotation
messages: Membrane

31033:LOC101076370
gene id: 31033:LOC101076370
uniprot id: H2VBK0
names: Similarity
messages: Belongs to the NGF-beta family.

31033:paqr7
gene id: 31033:paqr7
uniprot id: Q19WU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

31033:f9
gene id: 31033:f9
uniprot id: H2T095
uniprot id: Q804W8
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Factor IX is a vitamin K-dependent plasma protein that participates in the intrinsic pathway of blood coagulation by converting factor X to its active form in the presence of Ca(2+) ions, phospholipids, and factor VIIIa.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular space

31033:smad6
gene id: 31033:smad6
uniprot id: A0A3B5KAY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dwarfin/SMAD family.
messages: Cytoplasm
messages: Nucleus

31033:LOC101077993
gene id: 31033:LOC101077993
uniprot id: H2SNP7
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c family.
messages: Binds 1 heme group per subunit.
messages: Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.
messages: Mitochondrion intermembrane space

31033:tpm4-2
gene id: 31033:tpm4-2
uniprot id: A0A3B5K7L1
uniprot id: Q805C2
uniprot id: Q805C3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tropomyosin family.
messages: cytoskeleton

31033:LOC101063122
gene id: 31033:LOC101063122
uniprot id: A0A674MBK7
names: Similarity
messages: Belongs to the BicD family.

31033:ccnf
gene id: 31033:ccnf
uniprot id: A0A674P319
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cyclin family. Cyclin AB subfamily.
messages: Essential for the control of the cell cycle at the G2/M (mitosis) transition.
messages: Interacts with the CDK1 protein kinase to form a serine/threonine kinase holoenzyme complex also known as maturation promoting factor (MPF). The cyclin subunit imparts substrate specificity to the complex.
messages: centriole
messages: perinuclear region

31033:lhpp
gene id: 31033:lhpp
uniprot id: H2TK63
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

31033:kif4a
gene id: 31033:kif4a
uniprot id: H2SBR3
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

31033:dcp1a
gene id: 31033:dcp1a
uniprot id: H2S6N6
names: Similarity
messages: Belongs to the DCP1 family.

31033:ankrd13b
gene id: 31033:ankrd13b
uniprot id: A0A674PS19
names: Function
names: Subcellular Location Annotation
messages: Endosome
messages: Late endosome
messages: Membrane
messages: Ubiquitin-binding protein that specifically recognizes and binds 'Lys-63'-linked ubiquitin. Does not bind 'Lys-48'-linked ubiquitin. Positively regulates the internalization of ligand-activated EGFR by binding to the Ub moiety of ubiquitinated EGFR at the cell membrane.

31033:LOC101077131
gene id: 31033:LOC101077131
uniprot id: H2S501
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

31033:LOC101079890
gene id: 31033:LOC101079890
uniprot id: A0A3B5K140
names: Similarity
messages: Belongs to the eIF4E-binding protein family.

31033:cpsf7
gene id: 31033:cpsf7
uniprot id: H2V519
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM CPSF6/7 family.
messages: Nucleus

31033:aox1
gene id: 31033:aox1
uniprot id: M1ZML4
names: Cofactor
names: Similarity
messages: Belongs to the xanthine dehydrogenase family.
messages: Binds 1 Mo-molybdopterin (Mo-MPT) cofactor per subunit.
messages: Binds 2 [2Fe-2S] clusters.

31033:sart3
gene id: 31033:sart3
uniprot id: A0A674P0J2
names: Subcellular Location Annotation
messages: nucleoplasm

31033:LOC101079015
gene id: 31033:LOC101079015
uniprot id: H2UDB6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAD-like hydrolase superfamily. EYA family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nucleus

31033:stk32a
gene id: 31033:stk32a
uniprot id: H2RRI3
names: Similarity
messages: Belongs to the protein kinase superfamily.

31033:clvs2
gene id: 31033:clvs2
uniprot id: H2TWM5
names: Subcellular Location Annotation
messages: Early endosome membrane
messages: Endosome membrane
messages: Vesicle
messages: clathrin-coated vesicle
messages: trans-Golgi network membrane

31033:fbl
gene id: 31033:fbl
uniprot id: H2SDJ0
names: Similarity
messages: Belongs to the methyltransferase superfamily. Fibrillarin family.

31033:nrp2
gene id: 31033:nrp2
uniprot id: A0A674NN94
names: Caution
names: Similarity
messages: Belongs to the neuropilin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

31033:LOC101070684
gene id: 31033:LOC101070684
uniprot id: H2STM0
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

31033:usp13
gene id: 31033:usp13
uniprot id: H2V7E3
names: Similarity
messages: Belongs to the peptidase C19 family.

31033:LOC101070798
gene id: 31033:LOC101070798
uniprot id: A0A3B5KH67
names: Subcellular Location Annotation
messages: Nucleus

31033:med20
gene id: 31033:med20
uniprot id: H2TCJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 20 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

31033:dio2
gene id: 31033:dio2
uniprot id: B1B570
names: Function
names: Similarity
messages: Belongs to the iodothyronine deiodinase family.
messages: Responsible for the deiodination of T4 (3,5,3',5'-tetraiodothyronine).

31033:pdcl3
gene id: 31033:pdcl3
uniprot id: H2UNB6
names: Similarity
messages: Belongs to the phosducin family.

31033:bace1
gene id: 31033:bace1
uniprot id: H2T442
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A1 family.
messages: Membrane
messages: Membrane raft
messages: Recycling endosome
messages: trans-Golgi network

31033:cdca7
gene id: 31033:cdca7
uniprot id: H2V7J1
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

31033:LOC101079833
gene id: 31033:LOC101079833
uniprot id: H2USL2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNAP-25 family.
messages: Cell membrane
messages: Plays an important role in the synaptic function of specific neuronal systems. Associates with proteins involved in vesicle docking and membrane fusion.
messages: synaptosome

31033:acta1a
gene id: 31033:acta1a
uniprot id: P68140
names: Function
names: Miscellaneous
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
names: Tissue Specificity
messages: Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.
messages: Belongs to the actin family.
messages: In vertebrates 3 main groups of actin isoforms, alpha, beta and gamma have been identified. The alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. The beta and gamma actins coexist in most cell types as components of the cytoskeleton and as mediators of internal cell motility.
messages: Methylated at His-75 by SETD3.
messages: Monomethylation at Lys-86 (K84me1) regulates actin-myosin interaction and actomyosin-dependent processes. Demethylation by ALKBH4 is required for maintaining actomyosin dynamics supporting normal cleavage furrow ingression during cytokinesis and cell migration.
messages: Oxidation of Met-46 and Met-49 by MICALs (MICAL1, MICAL2 or MICAL3) to form methionine sulfoxide promotes actin filament depolymerization. MICAL1 and MICAL2 produce the (R)-S-oxide form. The (R)-S-oxide form is reverted by MSRB1 and MSRB2, which promotes actin repolymerization.
messages: Polymerization of globular actin (G-actin) leads to a structural filament (F-actin) in the form of a two-stranded helix. Each actin can bind to 4 others.
messages: Predominantly expressed in skeletal muscle. Lower levels in heart.
messages: There are two different alpha-skeletal actins in Fugu rubripes.
messages: cytoskeleton

31033:nkx2-3
gene id: 31033:nkx2-3
uniprot id: A0A3B5K9U3
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

31033:LOC101069242
gene id: 31033:LOC101069242
uniprot id: A0A674PRJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with GIRK2, GIRK3 or GIRK4 to form a G-protein activated heteromultimer pore-forming unit. The resulting inward current is much larger.
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family. KCNJ3 subfamily.
messages: Membrane
messages: This potassium channel is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. This receptor plays a crucial role in regulating the heartbeat.

31033:vps41
gene id: 31033:vps41
uniprot id: H2T3Z4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS41 family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane
messages: Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport pathways.
messages: clathrin-coated vesicle
messages: trans-Golgi network

31033:LOC101077225
gene id: 31033:LOC101077225
uniprot id: A0A674PC53
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

31033:lamtor1
gene id: 31033:lamtor1
uniprot id: A0A3B5K3P4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LAMTOR1 family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane
messages: Membrane

31033:slc35c1
gene id: 31033:slc35c1
uniprot id: A0A3B5JZ03
uniprot id: A0A3B5KC69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TPT transporter family. SLC35C subfamily.
messages: Membrane

31033:LOC101065656
gene id: 31033:LOC101065656
uniprot id: H2T5C6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I 75 kDa subunit family.
messages: Mitochondrion inner membrane

31033:LOC101076333
gene id: 31033:LOC101076333
uniprot id: H2SBK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Golgi pH regulator (TC 1.A.38) family.
messages: Membrane

31033:LOC101075889
gene id: 31033:LOC101075889
uniprot id: H2UXP4
names: Similarity
messages: Belongs to the flagellar radial spoke RSP3 family.

31033:cmpk1
gene id: 31033:cmpk1
uniprot id: H2RXA2
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family. UMP-CMP kinase subfamily.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Monomer.
messages: Nucleus

31033:pacs1
gene id: 31033:pacs1
uniprot id: H2SZB6
names: Similarity
messages: Belongs to the PACS family.

31033:ddost
gene id: 31033:ddost
uniprot id: H2S8C7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DDOST 48 kDa subunit family.
messages: Component of the oligosaccharyltransferase (OST) complex.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER).

31033:spout1
gene id: 31033:spout1
uniprot id: A0A3B5K473
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily.

31033:kdm2a
gene id: 31033:kdm2a
uniprot id: H2UF78
names: Similarity
messages: Belongs to the JHDM1 histone demethylase family. JHDM1D subfamily.

31033:tnfsf12
gene id: 31033:tnfsf12
uniprot id: A0A674NCA0
names: Similarity
messages: Belongs to the tumor necrosis factor family.

31033:rbpms2
gene id: 31033:rbpms2
uniprot id: A0A3B5KJR4
names: Subcellular Location Annotation
messages: Cytoplasm

31033:tmem38a
gene id: 31033:tmem38a
uniprot id: H2SXH9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM38 family.
messages: Membrane
messages: Monovalent cation channel required for maintenance of rapid intracellular calcium release. May act as a potassium counter-ion channel that functions in synchronization with calcium release from intracellular stores.

31033:LOC101073848
gene id: 31033:LOC101073848
uniprot id: A0A3B5KM22
names: Subcellular Location Annotation
messages: Membrane

31033:LOC101079133
gene id: 31033:LOC101079133
uniprot id: A0A3B5JUW0
names: Function
names: Similarity
messages: Belongs to the parvalbumin family.
messages: In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions.

31033:lingo3
gene id: 31033:lingo3
uniprot id: A0A674PNP4
names: Subcellular Location Annotation
messages: Membrane

31033:trappc4
gene id: 31033:trappc4
uniprot id: H2RM41
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAPP small subunits family.
messages: Endoplasmic reticulum
messages: Part of the multisubunit transport protein particle (TRAPP) complex.
messages: cis-Golgi network

31033:LOC101067409
gene id: 31033:LOC101067409
uniprot id: H2RYS6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATG9 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Phospholipid scramblase involved in autophagy. Cycles between the preautophagosomal structure/phagophore assembly site (PAS) and the cytoplasmic vesicle pool and supplies membrane for the growing autophagosome. Lipid scramblase activity plays a key role in preautophagosomal structure/phagophore assembly by distributing the phospholipids that arrive through ATG2 from the cytoplasmic to the luminal leaflet of the bilayer, thereby driving autophagosomal membrane expansion.
messages: Preautophagosomal structure membrane

31033:tcea1
gene id: 31033:tcea1
uniprot id: H2TY90
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFS-II family.
messages: Necessary for efficient RNA polymerase II transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by S-II allows the resumption of elongation from the new 3'-terminus.
messages: Nucleus

31033:get1
gene id: 31033:get1
uniprot id: H2RSA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WRB/GET1 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

31033:mapre1
gene id: 31033:mapre1
uniprot id: A0A3B5KI06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAPRE family.
messages: centrosome
messages: spindle pole

31033:LOC101061817
gene id: 31033:LOC101061817
uniprot id: A0A674MEU8
names: Similarity
messages: Belongs to the FAM102 family.

31033:LOC101076958
gene id: 31033:LOC101076958
uniprot id: A0A674PDY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

31033:exoc3
gene id: 31033:exoc3
uniprot id: H2TC32
names: Similarity
messages: Belongs to the SEC6 family.

31033:LOC101077727
gene id: 31033:LOC101077727
uniprot id: A0A3B5KTK8
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.

31033:bcap29
gene id: 31033:bcap29
uniprot id: H2UXB9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BCAP29/BCAP31 family.
messages: Endoplasmic reticulum membrane
messages: May play a role in anterograde transport of membrane proteins from the endoplasmic reticulum to the Golgi.
messages: Membrane

31033:LOC101079400
gene id: 31033:LOC101079400
uniprot id: A0A3B5KQN5
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

31033:slc25a25
gene id: 31033:slc25a25
uniprot id: H2UCT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

31033:LOC101073215
gene id: 31033:LOC101073215
uniprot id: H2TZX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: tight junction

31033:ddrgk1
gene id: 31033:ddrgk1
uniprot id: A0A3B5K6A1
names: Similarity
messages: Belongs to the DDRGK1 family.

31033:LOC101075099
gene id: 31033:LOC101075099
uniprot id: H2UBD3
names: Subcellular Location Annotation
messages: Membrane

31033:LOC101070352
gene id: 31033:LOC101070352
uniprot id: A0A3B5KB92
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

31033:LOC101066440
gene id: 31033:LOC101066440
uniprot id: A0A674PFX7
names: Subcellular Location Annotation
messages: Membrane

31033:babam1
gene id: 31033:babam1
uniprot id: A0A3B5KE12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BABAM1 family.
messages: Nucleus

31033:LOC101065877
gene id: 31033:LOC101065877
uniprot id: H2T8Y2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SH3PXD2 family.
messages: Cytoplasm
messages: podosome

31033:uhrf2
gene id: 31033:uhrf2
uniprot id: H2UJY8
names: Subcellular Location Annotation
messages: Nucleus

31033:LOC101077642
gene id: 31033:LOC101077642
uniprot id: H2SEN1
names: Domain
names: Similarity
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Belongs to the annexin family.

31033:raf1
gene id: 31033:raf1
uniprot id: A0A6D2XWC0
uniprot id: Q5NSW0
names: Similarity
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. RAF subfamily.

31033:sec22a
gene id: 31033:sec22a
uniprot id: H2UHI8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Endoplasmic reticulum membrane
messages: May be involved in vesicle transport between the ER and the Golgi complex.
messages: Membrane

31033:ndufb11
gene id: 31033:ndufb11
uniprot id: A0A674NM05
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFB11 subunit family.
messages: Membrane

31033:LOC101080083
gene id: 31033:LOC101080083
uniprot id: A0A674PPM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SYG1 (TC 2.A.94) family.
messages: Membrane

31033:LOC101061076
gene id: 31033:LOC101061076
uniprot id: A0A674NTF3
names: Subcellular Location Annotation
messages: Membrane

31033:trpt1
gene id: 31033:trpt1
uniprot id: A0A3B5KDI8
names: Function
names: Similarity
messages: Belongs to the KptA/TPT1 family.
messages: Catalyzes the last step of tRNA splicing, the transfer of the splice junction 2'-phosphate from ligated tRNA to NAD to produce ADP-ribose 1''-2'' cyclic phosphate.

31033:LOC101067723
gene id: 31033:LOC101067723
uniprot id: A0A3B5KRR9
uniprot id: A0A674NZ98
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rho family. CDC42 subfamily.
messages: Cell membrane
messages: Membrane
messages: Midbody
messages: Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state.

31033:cxcr5
gene id: 31033:cxcr5
uniprot id: F1SWA9
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

31033:ints10
gene id: 31033:ints10
uniprot id: H2TIL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Integrator subunit 10 family.
messages: Nucleus

31033:nde1
gene id: 31033:nde1
uniprot id: H2TQH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nudE family.
messages: centrosome
messages: spindle

31033:LOC101064414
gene id: 31033:LOC101064414
uniprot id: A0A674N1P0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AXUD1 family.
messages: Nucleus

31033:LOC101071738
gene id: 31033:LOC101071738
uniprot id: A0A674PR36
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFC2 subunit family.
messages: Mitochondrion inner membrane

31033:cers6
gene id: 31033:cers6
uniprot id: A0A674MZB9
names: Function
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

31033:KEF89 p05
gene id: 31033:KEF89_p05
uniprot id: Q8HCV7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4L family.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.
messages: Membrane
messages: Mitochondrion inner membrane

31033:stmn4
gene id: 31033:stmn4
uniprot id: H2RT81
names: Similarity
messages: Belongs to the stathmin family.

31033:LOC101061184
gene id: 31033:LOC101061184
uniprot id: H2TCX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC29A/ENT transporter (TC 2.A.57) family.
messages: Membrane

31033:LOC101079811
gene id: 31033:LOC101079811
uniprot id: H2SNP7
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c family.
messages: Binds 1 heme group per subunit.
messages: Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.
messages: Mitochondrion intermembrane space

31033:LOC101078514
gene id: 31033:LOC101078514
uniprot id: H2V4E3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSG1 family.
messages: Membrane

31033:poc5
gene id: 31033:poc5
uniprot id: A0A3B5KMW9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POC5 family.
messages: Essential for the assembly of the distal half of centrioles, required for centriole elongation.
messages: centriole

31033:npl
gene id: 31033:npl
uniprot id: H2V8I4
names: Similarity
names: Subunit
messages: Belongs to the DapA family.
messages: Homotetramer.

31033:LOC101069505
gene id: 31033:LOC101069505
uniprot id: H2SEM5
names: Caution
names: Function
names: Miscellaneous
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acylated. Acylation may be a prerequisite for conversion of the monomeric 37 kDa laminin receptor precursor (37LRP) to the mature dimeric 67 kDa laminin receptor (67LR), and may provide a mechanism for membrane association.
messages: Belongs to the universal ribosomal protein uS2 family.
messages: Cell membrane
messages: Cleaved by stromelysin-3 (ST3) at the cell surface. Cleavage by stromelysin-3 may be a mechanism to alter cell-extracellular matrix interactions.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer (37LRP) and homodimer (67LR). Component of the small ribosomal subunit. Mature ribosomes consist of a small (40S) and a large (60S) subunit. The 40S subunit contains about 33 different proteins and 1 molecule of RNA (18S). The 60S subunit contains about 49 different proteins and 3 molecules of RNA (28S, 5.8S and 5S). Interacts with RPS21. Interacts with several laminins including at least LAMB1. Interacts with MDK.
messages: Nucleus
messages: Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. Also functions as a cell surface receptor for laminin. Plays a role in cell adhesion to the basement membrane and in the consequent activation of signaling transduction pathways. May play a role in cell fate determination and tissue morphogenesis.
messages: This protein appears to have acquired a second function as a laminin receptor specifically in the vertebrate lineage.

31033:LOC101068751
gene id: 31033:LOC101068751
uniprot id: H2UDT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

31033:LOC101072418
gene id: 31033:LOC101072418
uniprot id: A0A674PCM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the band 7/mec-2 family.
messages: Membrane

31033:ndufa7
gene id: 31033:ndufa7
uniprot id: A0A674M8Q6
names: Function
names: Similarity
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA7 subunit family.
messages: Complex I is composed of 45 different subunits.

31033:LOC101061397
gene id: 31033:LOC101061397
uniprot id: A0A3B5KVM6
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

31033:naga
gene id: 31033:naga
uniprot id: H2UQ40
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycosyl hydrolase 27 family.
messages: Homodimer.
messages: Lysosome

31033:ell
gene id: 31033:ell
uniprot id: H2V909
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELL/occludin family.
messages: Nucleus

31033:LOC101072470
gene id: 31033:LOC101072470
uniprot id: H2SB25
names: Similarity
messages: Belongs to the pellino family.

31033:LOC101064687
gene id: 31033:LOC101064687
uniprot id: H2UBJ0
names: Similarity
messages: Belongs to the NifU family.

31033:nfic
gene id: 31033:nfic
uniprot id: H2SNH2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CTF/NF-I family.
messages: Binds DNA as a homodimer.
messages: Nucleus
messages: Recognizes and binds the palindromic sequence 5'-TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication.

31033:LOC101068316
gene id: 31033:LOC101068316
uniprot id: A0A674MLM6
names: Similarity
messages: Belongs to the protein kinase superfamily.

31033:pnpo
gene id: 31033:pnpo
uniprot id: H2U3U1
names: Function
names: Similarity
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).

31033:ugt1a1
gene id: 31033:ugt1a1
uniprot id: H2T5F6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UDP-glycosyltransferase family.
messages: Membrane

31033:il-20
gene id: 31033:il-20
uniprot id: Q2PDG6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-10 family.
messages: Immune regulatory cytokine.
messages: Secreted

31033:tbxas1
gene id: 31033:tbxas1
uniprot id: H2T1N2
names: Similarity
messages: Belongs to the cytochrome P450 family.

31033:cutc
gene id: 31033:cutc
uniprot id: A0A3B5K3T0
names: Similarity
messages: Belongs to the CutC family.

31033:rps16
gene id: 31033:rps16
uniprot id: A0A674MJE9
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

31033:LOC101075459
gene id: 31033:LOC101075459
uniprot id: H2TYI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

31033:serp1
gene id: 31033:serp1
uniprot id: H2VAC7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RAMP4 family.
messages: Endoplasmic reticulum membrane
messages: May interact with target proteins during translocation into the lumen of the endoplasmic reticulum. May protect unfolded target proteins against degradation and facilitate correct glycosylation.
messages: Membrane

31033:ncbp1
gene id: 31033:ncbp1
uniprot id: H2SJV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NCBP1 family.
messages: Nucleus

31033:LOC101064314
gene id: 31033:LOC101064314
uniprot id: A0A674N5T2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAVIN family.
messages: caveola

31033:cldn5c
gene id: 31033:cldn5c
uniprot id: Q6E5Q8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

31033:LOC619285
gene id: 31033:LOC619285
uniprot id: Q9I9R2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
messages: Membrane
messages: photoreceptor outer segment

31033:park7
gene id: 31033:park7
uniprot id: A0A3B5KKN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C56 family.
messages: Membrane raft

31033:LOC101068336
gene id: 31033:LOC101068336
uniprot id: A0A674MCY5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IWR1/SLC7A6OS family.
messages: Cytoplasm
messages: Directs RNA polymerase II nuclear import.
messages: Nucleus

31033:pigs
gene id: 31033:pigs
uniprot id: H2V3B4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGS family.
messages: Endoplasmic reticulum membrane
messages: Membrane

31033:nppa
gene id: 31033:nppa
uniprot id: Q805D8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the natriuretic peptide family.
messages: Hormone playing a key role in cardiovascular homeostasis through regulation of natriuresis, diuresis, and vasodilation. Has a cGMP-stimulating activity (By similarity).
messages: Secreted

31033:LOC101065873
gene id: 31033:LOC101065873
uniprot id: A0A3B5K8X7
names: Subcellular Location Annotation
messages: centriole
messages: cilium
messages: cis-Golgi network

31033:gskip
gene id: 31033:gskip
uniprot id: H2VC04
names: Similarity
messages: Belongs to the GSKIP family.

31033:LOC105417758
gene id: 31033:LOC105417758
uniprot id: H2UYB5
names: Similarity
messages: Belongs to the DCP1 family.

31033:actr2
gene id: 31033:actr2
uniprot id: A0A674PNI1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament.
messages: Belongs to the actin family. ARP2 subfamily.
messages: Component of the Arp2/3 complex.
messages: cytoskeleton

31033:tspan31
gene id: 31033:tspan31
uniprot id: H2RKJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

31033:LOC101080112
gene id: 31033:LOC101080112
uniprot id: A0A3B5K117
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 1 family. Gal/GlcNAc/GalNAc subfamily.
messages: Membrane

31033:LOC100049642
gene id: 31033:LOC100049642
uniprot id: A1KZS8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. Flotillin subfamily.
messages: Endosome
messages: Heterooligomeric complex.
messages: Membrane

31033:med24
gene id: 31033:med24
uniprot id: A0A3B5KCJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 24 family.
messages: Nucleus

31033:LOC101073808
gene id: 31033:LOC101073808
uniprot id: H2SPK9
names: Similarity
messages: Belongs to the OSBP family.

31033:tm7sf2
gene id: 31033:tm7sf2
uniprot id: A0A674NRC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERG4/ERG24 family.
messages: Membrane

31033:LOC101067452
gene id: 31033:LOC101067452
uniprot id: A0A3B5KDH2
names: Subcellular Location Annotation
messages: filopodium
messages: microvillus
messages: ruffle

31033:sbds
gene id: 31033:sbds
uniprot id: A0A3B5KP44
names: Function
names: Similarity
messages: Belongs to the SDO1/SBDS family.
messages: Required for the assembly of mature ribosomes and ribosome biogenesis. Together with EFL1, triggers the GTP-dependent release of EIF6 from 60S pre-ribosomes in the cytoplasm, thereby activating ribosomes for translation competence by allowing 80S ribosome assembly and facilitating EIF6 recycling to the nucleus, where it is required for 60S rRNA processing and nuclear export. Required for normal levels of protein synthesis. May play a role in cellular stress resistance. May play a role in cellular response to DNA damage. May play a role in cell proliferation.

31033:KEF89 p11
gene id: 31033:KEF89_p11
uniprot id: Q8HCW3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
messages: Membrane
messages: Mitochondrion inner membrane

31033:tmem41b
gene id: 31033:tmem41b
uniprot id: H2V5Z1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM41 family.
messages: Membrane

31033:anapc11
gene id: 31033:anapc11
uniprot id: A0A674MX98
names: Similarity
messages: Belongs to the RING-box family.

31033:tafa3
gene id: 31033:tafa3
uniprot id: A0A3B5KC92
names: Similarity
messages: Belongs to the TAFA family.

31033:LOC101065014
gene id: 31033:LOC101065014
uniprot id: H2V9T3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. ATF subfamily.
messages: Endoplasmic reticulum membrane
messages: Membrane

31033:LOC446071
gene id: 31033:LOC446071
uniprot id: O46705
names: Similarity
messages: Belongs to the MHC class I family.

31033:tada3
gene id: 31033:tada3
uniprot id: H2TRW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NGG1 family.
messages: Nucleus

31033:tbr1
gene id: 31033:tbr1
uniprot id: H2SJ50
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

31033:rfc4
gene id: 31033:rfc4
uniprot id: H2SLF6
names: Similarity
messages: Belongs to the activator 1 small subunits family.

31033:LOC101076423
gene id: 31033:LOC101076423
uniprot id: A0A674NBB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nectin family.
messages: Membrane

31033:ipo11
gene id: 31033:ipo11
uniprot id: A0A3B5KBN2
names: Subcellular Location Annotation
messages: Cytoplasm

31033:cd3e
gene id: 31033:cd3e
uniprot id: Q589Z2
names: Subcellular Location Annotation
messages: Membrane

31033:LOC101061541
gene id: 31033:LOC101061541
uniprot id: A0A674NN63
names: Similarity
messages: Belongs to the glutathione peroxidase family.

31033:foxk1
gene id: 31033:foxk1
uniprot id: H2U199
names: Subcellular Location Annotation
messages: Nucleus

31033:rab32
gene id: 31033:rab32
uniprot id: H2TDE9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Membrane
messages: The small GTPases Rab are key regulators in vesicle trafficking.

31033:pptc7
gene id: 31033:pptc7
uniprot id: A0A3B5K8P1
names: Similarity
messages: Belongs to the PP2C family.

31033:fev
gene id: 31033:fev
uniprot id: H2S4M5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

31033:LOC101065051
gene id: 31033:LOC101065051
uniprot id: H2SBK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

31033:mdh1
gene id: 31033:mdh1
uniprot id: H2TUM0
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 2 family.
messages: Interconverts simultaneously and stereospecifically pyruvate and lactate with concomitant interconversion of NADH and NAD(+).

31033:LOC101061159
gene id: 31033:LOC101061159
uniprot id: A0A674MFM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

31033:tarbp2
gene id: 31033:tarbp2
uniprot id: H2UIJ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TARBP2 family.
messages: Cytoplasm
messages: Required for formation of the RNA induced silencing complex (RISC). Component of the RISC loading complex (RLC), also known as the micro-RNA (miRNA) loading complex (miRLC), which is composed of DICER1, AGO2 and TARBP2. Within the RLC/miRLC, DICER1 and TARBP2 are required to process precursor miRNAs (pre-miRNAs) to mature miRNAs and then load them onto AGO2. AGO2 bound to the mature miRNA constitutes the minimal RISC and may subsequently dissociate from DICER1 and TARBP2. May also play a role in the production of short interfering RNAs (siRNAs) from double-stranded RNA (dsRNA) by DICER1.
messages: Self-associates. Component of the RISC loading complex (RLC), or micro-RNA (miRNA) loading complex (miRLC), which is composed of DICER1, AGO2 and TARBP2. Note that the trimeric RLC/miRLC is also referred to as RISC.

31033:slc9a8
gene id: 31033:slc9a8
uniprot id: H2RU01
names: Similarity
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.

31033:LOC101068133
gene id: 31033:LOC101068133
uniprot id: H2TDW3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 56 family.
messages: Cell membrane
messages: Early endosome
messages: Endoplasmic reticulum
messages: Endosome
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: acrosome

31033:coq4
gene id: 31033:coq4
uniprot id: A0A674MYP2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COQ4 family.
messages: Component of a multi-subunit COQ enzyme complex, composed of at least COQ3, COQ4, COQ5, COQ6, COQ7 and COQ9.
messages: Component of the coenzyme Q biosynthetic pathway. May play a role in organizing a multi-subunit COQ enzyme complex required for coenzyme Q biosynthesis. Required for steady-state levels of other COQ polypeptides.
messages: Mitochondrion inner membrane

31033:LOC101070310
gene id: 31033:LOC101070310
uniprot id: H2V154
names: Subcellular Location Annotation
messages: Nucleus

31033:LOC101066176
gene id: 31033:LOC101066176
uniprot id: A0A674MB44
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP dependent phosphorylation of adenosine and other related nucleoside analogs to monophosphate derivatives.
messages: Belongs to the carbohydrate kinase PfkB family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Monomer.
messages: Nucleus

31033:fam20b
gene id: 31033:fam20b
uniprot id: I7KJQ7
names: Similarity
messages: Belongs to the FAM20 family.

31033:camk2a
gene id: 31033:camk2a
uniprot id: A0A674MG54
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily.

31033:trmt11
gene id: 31033:trmt11
uniprot id: Q7T065
names: Function
messages: Catalytic subunit of an S-adenosyl-L-methionine-dependent tRNA methyltransferase complex that mediates the methylation of the guanosine nucleotide at position 10 (m2G10) in tRNAs.

31033:rpl7a
gene id: 31033:rpl7a
uniprot id: O57592
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL8 family.
messages: Component of the large ribosomal subunit.
messages: Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.
messages: Cytoplasm

31033:hbp1
gene id: 31033:hbp1
uniprot id: A0A3B5KJ58
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Transcriptional repressor that binds to the promoter region of target genes. Plays a role in the regulation of the cell cycle and of the Wnt pathway. Binds preferentially to the sequence 5'-TTCATTCATTCA-3'. Binding to the histone H1.0 promoter is enhanced by interaction with RB1. Disrupts the interaction between DNA and TCF4.

31033:LOC101070365
gene id: 31033:LOC101070365
uniprot id: D4AHP2
names: Similarity
messages: Belongs to the IL-17 family.

31033:hoxc9
gene id: 31033:hoxc9
uniprot id: O42502
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

31033:gamt
gene id: 31033:gamt
uniprot id: A0A3B5K6S0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RMT2 methyltransferase family.
messages: Converts guanidinoacetate to creatine, using S-adenosylmethionine as the methyl donor.
messages: Monomer.

31033:calhm3
gene id: 31033:calhm3
uniprot id: H2RKV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CALHM family.
messages: Membrane

31033:LOC101063823
gene id: 31033:LOC101063823
uniprot id: H2USZ6
names: Similarity
messages: Belongs to the PDE6D/unc-119 family.

31033:LOC101068997
gene id: 31033:LOC101068997
uniprot id: H2SUA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the potassium channel family. B (Shab) (TC 1.A.1.2) subfamily. Kv2.1/KCNB1 sub-subfamily.
messages: Lateral cell membrane
messages: Membrane
messages: Perikaryon
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane
messages: axon
messages: sarcolemma
messages: synaptosome

31033:comt
gene id: 31033:comt
uniprot id: H2UD96
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family.

31033:LOC101072782
gene id: 31033:LOC101072782
uniprot id: A0A674NU84
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.

31033:pigh
gene id: 31033:pigh
uniprot id: A0A3B5K8G5
names: Similarity
messages: Belongs to the PIGH family.

31033:xpa
gene id: 31033:xpa
uniprot id: H2UR40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XPA family.
messages: Nucleus

31033:yif1a
gene id: 31033:yif1a
uniprot id: H2U1G6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YIF1 family.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Has a role in transport between endoplasmic reticulum and Golgi.
messages: Membrane

31033:skp1
gene id: 31033:skp1
uniprot id: H2T5K0
names: Function
names: Similarity
messages: Belongs to the SKP1 family.
messages: Essential component of the SCF (SKP1-CUL1-F-box protein) ubiquitin ligase complex, which mediates the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. In the SCF complex, serves as an adapter that links the F-box protein to CUL1.

31033:LOC101069670
gene id: 31033:LOC101069670
uniprot id: H2T0H5
names: Similarity
messages: Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.

31033:LOC101075480
gene id: 31033:LOC101075480
uniprot id: H2TPN5
names: Similarity
names: Subunit
messages: Homodimer.
messages: In the C-terminal section; belongs to the phosphoglycerate mutase family.

31033:nlk
gene id: 31033:nlk
uniprot id: Q9I863
names: Activity Regulation
names: Similarity
messages: Activated by threonine and tyrosine phosphorylation.
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.

31033:psmd12
gene id: 31033:psmd12
uniprot id: A0A3B5K381
names: Similarity
messages: Belongs to the proteasome subunit p55 family.

31033:yars
gene id: 31033:yars
uniprot id: H2UGK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Nucleus

31033:glyctk
gene id: 31033:glyctk
uniprot id: A0A3B5KAV1
names: Similarity
messages: Belongs to the glycerate kinase type-2 family.

31033:ets1
gene id: 31033:ets1
uniprot id: A0A3B5K0T6
uniprot id: A0A3B5KH81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

31033:foxo3
gene id: 31033:foxo3
uniprot id: H2RT85
names: Subcellular Location Annotation
messages: Nucleus

31033:rpl17
gene id: 31033:rpl17
uniprot id: A0A3B5KR88
names: Similarity
messages: Belongs to the universal ribosomal protein uL22 family.

31033:thoc5
gene id: 31033:thoc5
uniprot id: A0A674PFK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the THOC5 family.
messages: Nucleus

31033:cacul1
gene id: 31033:cacul1
uniprot id: H2VA15
names: Similarity
messages: Belongs to the cullin family.

31033:LOC101076676
gene id: 31033:LOC101076676
uniprot id: H2UHT6
names: Similarity
messages: Belongs to the peptidase M17 family.

31033:LOC101073239
gene id: 31033:LOC101073239
uniprot id: H2UHN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
messages: Cytoplasm

31033:th
gene id: 31033:th
uniprot id: A0JGX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.
messages: axon
messages: perinuclear region

31033:lsm7
gene id: 31033:lsm7
uniprot id: A0A3B5K7X9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP Sm proteins family.
messages: Nucleus

31033:LOC101073244
gene id: 31033:LOC101073244
uniprot id: A0A674NRC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.
messages: Cell membrane
messages: Membrane

31033:med16
gene id: 31033:med16
uniprot id: H2T4D7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 16 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

31033:lhx8
gene id: 31033:lhx8
uniprot id: H2V7E7
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

31033:cd8a
gene id: 31033:cd8a
uniprot id: Q2HWR4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

31033:LOC101072346
gene id: 31033:LOC101072346
uniprot id: H2TV93
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat LIS1/nudF family.
messages: Can self-associate. Component of the cytosolic PAF-AH (I) heterotetrameric enzyme, which is composed of PAFAH1B1 (beta), PAFAH1B2 (alpha2) and PAFAH1B3 (alpha1) subunits. The catalytic activity of the enzyme resides in the alpha1 (PAFAH1B3) and alpha2 (PAFAH1B2) subunits, whereas the beta subunit (PAFAH1B1) has regulatory activity. Trimer formation is not essential for the catalytic activity (By similarity). Interacts with dynein, dynactin, nde1 and ndel1.
messages: Can self-associate. Interacts with dynein, dynactin, NDE1 and NDEL1.
messages: Dimerization mediated by the LisH domain may be required to activate dynein.
messages: Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. May be required for proliferation of neuronal precursors and neuronal migration.
messages: centrosome
messages: cytoskeleton

31033:rad51
gene id: 31033:rad51
uniprot id: A0A3B5KBZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family. RAD51 subfamily.
messages: Nucleus
messages: Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination (HR). Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Recruited to resolve stalled replication forks during replication stress. Also involved in interstrand cross-link repair.

31033:zdhhc8
gene id: 31033:zdhhc8
uniprot id: Q2THV7
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family. ERF2/ZDHHC9 subfamily.
messages: Golgi apparatus membrane
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

31033:LOC101064658
gene id: 31033:LOC101064658
uniprot id: A0A3B5K887
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PUR DNA-binding protein family.
messages: Nucleus

31033:bckdk
gene id: 31033:bckdk
uniprot id: H2U5Z0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PDK/BCKDK protein kinase family.
messages: Mitochondrion matrix

31033:nkx6-3
gene id: 31033:nkx6-3
uniprot id: A0A3B5KUC6
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

31033:LOC101065546
gene id: 31033:LOC101065546
uniprot id: H2U656
names: Similarity
messages: Belongs to the AAA ATPase family.

31033:LOC100134850
gene id: 31033:LOC100134850
uniprot id: A8DPE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glucagon family.
messages: Secreted

31033:LOC101079141
gene id: 31033:LOC101079141
uniprot id: A0A674MIF7
names: Activity Regulation
names: Similarity
names: Subunit
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.
messages: Homodimer.
messages: Homodimerization via the leucine zipper domains is required for autophosphorylation.

31033:rbm47
gene id: 31033:rbm47
uniprot id: A0A674NZN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM RBM47 family.
messages: Nucleus

31033:ndufs2
gene id: 31033:ndufs2
uniprot id: H2TZM1
names: Similarity
messages: Belongs to the complex I 49 kDa subunit family.

31033:il-18
gene id: 31033:il-18
uniprot id: Q70T31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-1 family.
messages: Cytoplasm
messages: Secreted

31033:LOC101063498
gene id: 31033:LOC101063498
uniprot id: A0A674NU86
names: Similarity
messages: Belongs to the eukaryotic initiation factor 4E family.

31033:LOC101069382
gene id: 31033:LOC101069382
uniprot id: H2TYP1
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

31033:mct1a
gene id: 31033:mct1a
uniprot id: E7FKY6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.
messages: Cell membrane
messages: Membrane
messages: Proton-coupled monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate. Depending on the tissue and on cicumstances, mediates the import or export of lactic acid and ketone bodies. Required for normal nutrient assimilation, increase of white adipose tissue and body weight gain when on a high-fat diet. Plays a role in cellular responses to a high-fat diet by modulating the cellular levels of lactate and pyruvate, small molecules that contribute to the regulation of central metabolic pathways and insulin secretion, with concomitant effects on plasma insulin levels and blood glucose homeostasis.

31033:c8a
gene id: 31033:c8a
uniprot id: A0A674N1F2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complement C6/C7/C8/C9 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

31033:ppm1d
gene id: 31033:ppm1d
uniprot id: H2T2P5
names: Similarity
messages: Belongs to the PP2C family.

31033:sys1
gene id: 31033:sys1
uniprot id: A0A3B5K962
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SYS1 family.
messages: Golgi apparatus membrane
messages: Interacts with ARFRP1.
messages: Involved in protein trafficking. May serve as a receptor for ARFRP1.
messages: Membrane

31033:sfrp1
gene id: 31033:sfrp1
uniprot id: H2SI86
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the secreted frizzled-related protein (sFRP) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

31033:poglut2
gene id: 31033:poglut2
uniprot id: H2SYE9
names: Similarity
messages: Belongs to the KDELC family.

31033:mrpl10
gene id: 31033:mrpl10
uniprot id: Q1KKW0
names: Similarity
messages: Belongs to the universal ribosomal protein uL10 family.

31033:LOC101079018
gene id: 31033:LOC101079018
uniprot id: H2SSD7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxisomal membrane protein PXMP2/4 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

31033:gpr155b
gene id: 31033:gpr155b
uniprot id: Q1KKR1
names: Subcellular Location Annotation
messages: Membrane

31033:LOC101077253
gene id: 31033:LOC101077253
uniprot id: H2V5I3
names: Similarity
names: Subunit
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
messages: Homotetramer.

31033:snta1
gene id: 31033:snta1
uniprot id: A0A674N045
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the syntrophin family.
messages: Cell junction
messages: cytoskeleton

31033:nsfl1c
gene id: 31033:nsfl1c
uniprot id: H2T4F4
names: Subcellular Location Annotation
messages: Golgi stack

31033:LOC101061656
gene id: 31033:LOC101061656
uniprot id: A0A3B5KIF3
names: Similarity
messages: Belongs to the isthmin family.

31033:kti12
gene id: 31033:kti12
uniprot id: A0A3B5JZ81
names: Similarity
messages: Belongs to the KTI12 family.

31033:LOC101068244
gene id: 31033:LOC101068244
uniprot id: A0A674NPF3
uniprot id: A0A674P401
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRIM/RBCC family.
messages: Cytoplasm

31033:sfxn5
gene id: 31033:sfxn5
uniprot id: A0A674NYQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sideroflexin family.
messages: Membrane
messages: Mitochondrion membrane

31033:tnfa
gene id: 31033:tnfa
uniprot id: Q4W8A0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tumor necrosis factor family.
messages: Membrane

31033:hs3st5
gene id: 31033:hs3st5
uniprot id: H2SVZ8
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

31033:LOC101071385
gene id: 31033:LOC101071385
uniprot id: A0A3B5JUL2
uniprot id: A0A3B5KHY3
names: Similarity
messages: Belongs to the prickle / espinas / testin family.

31033:LOC101076688
gene id: 31033:LOC101076688
uniprot id: H2T0Z9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

31033:sh3gl1
gene id: 31033:sh3gl1
uniprot id: A0A3B5K5G1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endophilin family.
messages: Membrane

31033:LOC101062980
gene id: 31033:LOC101062980
uniprot id: A0A6D2WAW5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Membrane

31033:LOC101063193
gene id: 31033:LOC101063193
uniprot id: H2TFZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cAMP-dependent kinase regulatory chain family.
messages: Cell membrane
messages: Membrane

31033:LOC101067268
gene id: 31033:LOC101067268
uniprot id: A0A3B5KC02
names: Subcellular Location Annotation
messages: Membrane

31033:tp53inp2
gene id: 31033:tp53inp2
uniprot id: A0A3B5KL89
uniprot id: A0A674N5L2
names: Subcellular Location Annotation
messages: PML body
messages: autophagosome
messages: cytosol

31033:LOC101067638
gene id: 31033:LOC101067638
uniprot id: A0A674PNU4
names: Function
names: Similarity
messages: Belongs to the profilin family.
messages: Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG.

31033:LOC101066869
gene id: 31033:LOC101066869
uniprot id: H2SYJ0
uniprot id: H2SYJ1
names: Function
messages: Promotes degradation of target mRNA species. Plays a role in the regulation of circadian mRNA stability. Binds GTP and has GTPase activity.

31033:LOC101065066
gene id: 31033:LOC101065066
uniprot id: A0A3B5JVR8
uniprot id: A0A3B5KI60
names: Similarity
messages: Belongs to the RCAN family.

31033:LOC101075980
gene id: 31033:LOC101075980
uniprot id: H2RN87
names: Similarity
messages: Belongs to the JAKMIP family.

31033:memo1
gene id: 31033:memo1
uniprot id: A0A674MA87
names: Similarity
messages: Belongs to the MEMO1 family.

31033:LOC101073503
gene id: 31033:LOC101073503
uniprot id: A0A674PQI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurexophilin family.
messages: Secreted

31033:LOC101064834
gene id: 31033:LOC101064834
uniprot id: A0A674NJA5
names: Similarity
messages: Belongs to the paralemmin family.

31033:rdh13
gene id: 31033:rdh13
uniprot id: H2UNZ8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

31033:rps4x
gene id: 31033:rps4x
uniprot id: A0A674NI39
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS4 family.

31033:LOC101066223
gene id: 31033:LOC101066223
uniprot id: A0A3B5KK05
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UQCRH/QCR6 family.
messages: Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation.
messages: Mitochondrion inner membrane

31033:LOC101073060
gene id: 31033:LOC101073060
uniprot id: A0A3B5K9S6
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: RNA-binding protein that regulates alternative splicing events.

31033:zfy
gene id: 31033:zfy
uniprot id: H2V292
names: Subcellular Location Annotation
messages: Nucleus

31033:eif3m
gene id: 31033:eif3m
uniprot id: H2SSK7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CSN7/EIF3M family. CSN7 subfamily.
messages: Belongs to the eIF-3 subunit M family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
messages: Cytoplasm

31033:LOC101067123
gene id: 31033:LOC101067123
uniprot id: H2U0K0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycosyltransferase 14 family. XylT subfamily.
messages: Golgi apparatus membrane
messages: Membrane
messages: Monomer.

31033:lpcat2
gene id: 31033:lpcat2
uniprot id: H2TQX3
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

31033:pcyt1a
gene id: 31033:pcyt1a
uniprot id: A0A674N078
names: Function
names: Similarity
messages: Belongs to the cytidylyltransferase family.
messages: Catalyzes the key rate-limiting step in the CDP-choline pathway for phosphatidylcholine biosynthesis.

31033:LOC445980
gene id: 31033:LOC445980
uniprot id: Q6KC06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

31033:ergic1
gene id: 31033:ergic1
uniprot id: H2SXN3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERGIC family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Golgi apparatus membrane
messages: Plays a role in transport between endoplasmic reticulum and Golgi.

31033:etv6
gene id: 31033:etv6
uniprot id: H2T1G6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

31033:LOC101078241
gene id: 31033:LOC101078241
uniprot id: H2U0P6
names: Similarity
messages: Belongs to the ependymin family.

31033:LOC101073007
gene id: 31033:LOC101073007
uniprot id: H2UJH4
names: Similarity
messages: Belongs to the band 7/mec-2 family.

31033:atp6v0b
gene id: 31033:atp6v0b
uniprot id: H2UCX8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the V-ATPase proteolipid subunit family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Proton-conducting pore forming of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex. The V1 complex consists of three catalytic AB heterodimers that form a heterohexamer, three peripheral stalks each consisting of EG heterodimers, one central rotor including subunits D and F, and the regulatory subunits C and H. The proton translocation complex V0 consists of the proton transport subunit a, a ring of proteolipid subunits c9c'', rotary subunit d, subunits e and f, and the accessory subunits.
messages: clathrin-coated vesicle membrane

31033:pex3
gene id: 31033:pex3
uniprot id: H2UUY8
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Interacts with PEX19.
messages: Involved in peroxisome biosynthesis and integrity. Assembles membrane vesicles before the matrix proteins are translocated. As a docking factor for PEX19, is necessary for the import of peroxisomal membrane proteins in the peroxisomes.
messages: Peroxisome membrane

31033:LOC101079903
gene id: 31033:LOC101079903
uniprot id: A0A3B5KQ57
names: Similarity
names: Subunit
messages: Belongs to the 14-3-3 family.
messages: Homodimer, and heterodimer with other family members.

31033:LOC101063308
gene id: 31033:LOC101063308
uniprot id: H2UZD8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FMO family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Microsome membrane

31033:tmem177
gene id: 31033:tmem177
uniprot id: A0A3B5JUS8
names: Function
names: Similarity
messages: Belongs to the TMEM177 family.
messages: Plays a role in the early steps of cytochrome c oxidase subunit II (MT-CO2/COX2) maturation and is required for the stabilization of COX20 and the newly synthesized MT-CO2/COX2 protein.

31033:LOC101075191
gene id: 31033:LOC101075191
uniprot id: H2THL4
names: Similarity
messages: Belongs to the peptidase C14A family.

31033:ndufv2
gene id: 31033:ndufv2
uniprot id: H2T793
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.

31033:dph1
gene id: 31033:dph1
uniprot id: A0A674MI41
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the DPH1/DPH2 family. DPH1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the first step of diphthamide biosynthesis, a post-translational modification of histidine which occurs in elongation factor 2.

31033:rpl36a
gene id: 31033:rpl36a
uniprot id: P61486
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL42 family.
messages: Component of the large ribosomal subunit.
messages: Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.
messages: Cytoplasm

31033:meox1
gene id: 31033:meox1
uniprot id: H2SJ86
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

31033:LOC101070118
gene id: 31033:LOC101070118
uniprot id: H2T501
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/IRO homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

31033:naif1
gene id: 31033:naif1
uniprot id: H2UCP1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAIF1 family.
messages: Induces apoptosis.
messages: Nucleus

31033:b3gat1
gene id: 31033:b3gat1
uniprot id: A0A674MA33
uniprot id: Q5CB00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 43 family.
messages: Golgi apparatus membrane
messages: Membrane

31033:LOC101063010
gene id: 31033:LOC101063010
uniprot id: H2T4N5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

31033:vasn
gene id: 31033:vasn
uniprot id: H2SVU4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

31033:srp54
gene id: 31033:srp54
uniprot id: H2SY49
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Component of a signal recognition particle (SRP) complex that consists of a 7SL RNA molecule of 300 nucleotides and six protein subunits: SRP72, SRP68, SRP54, SRP19, SRP14 and SRP9.
messages: Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER). Binds to the signal sequence of presecretory proteins when they emerge from the ribosomes.
messages: Cytoplasm
messages: Has a two domain structure: the G-domain binds GTP; the M-domain binds the 7S RNA in presence of SRP19 and also binds the signal sequence.
messages: Nucleus speckle
messages: Signal recognition particle consists of a 7S RNA molecule and at least six protein subunits.

31033:rnf20
gene id: 31033:rnf20
uniprot id: H2T8F2
uniprot id: H2T8F3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BRE1 family.
messages: Nucleus

31033:runx2
gene id: 31033:runx2
uniprot id: Q8JFD4
names: Subcellular Location Annotation
messages: Nucleus

31033:igfbp6
gene id: 31033:igfbp6
uniprot id: H2RP73
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

31033:ifrd1
gene id: 31033:ifrd1
uniprot id: H2S0Y8
names: Similarity
messages: Belongs to the IFRD family.

31033:hint1
gene id: 31033:hint1
uniprot id: H2TJM3
names: Similarity
messages: Belongs to the HINT family.

31033:ndufa6
gene id: 31033:ndufa6
uniprot id: A0A674PDV5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed to be not involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I LYR family.
messages: Mammalian complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

31033:LOC101070140
gene id: 31033:LOC101070140
uniprot id: H2U1B0
names: Subcellular Location Annotation
messages: Membrane

31033:LOC101078798
gene id: 31033:LOC101078798
uniprot id: A0A674NK27
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGR2 family.
messages: Has antibacterial activity against a variety of bacteria including S.aureus, P.aeruginosa and M.tuberculosis. Acts by inducing bacterial membrane breakage.
messages: Induces production of reactive oxygen species (ROS) which are necessary for cell proliferation. May play a role in inducing oxidative DNA damage and replicative senescence. May play a role in the coordination of mitochondrial morphology and cell proliferation.
messages: Mitochondrion inner membrane

31033:LOC101062541
gene id: 31033:LOC101062541
uniprot id: A0A3B5K1E5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CART family.
messages: Secreted

31033:LOC101062046
gene id: 31033:LOC101062046
uniprot id: H2SPA9
names: Cofactor
names: Function
names: Subunit
messages: Binds 1 zinc ion per subunit.
messages: Homotetramer.
messages: Involved in the regulation of homocysteine metabolism.

31033:LOC101075148
gene id: 31033:LOC101075148
uniprot id: A0A674NZG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TDE1 family.
messages: Membrane

31033:ap4m1
gene id: 31033:ap4m1
uniprot id: A0A674MX47
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes medium subunit family.
messages: Component of the adaptor protein complex 4 (AP-4). Adaptor protein complexes are vesicle coat components involved both in vesicle formation and cargo selection. They control the vesicular transport of proteins in different trafficking pathways. AP-4 forms a non clathrin-associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system. It is also involved in protein sorting to the basolateral membrane in epithelial cells and the proper asymmetric localization of somatodendritic proteins in neurons. Within AP-4, the mu-type subunit AP4M1 is directly involved in the recognition and binding of tyrosine-based sorting signals found in the cytoplasmic part of cargos. The adaptor protein complex 4 (AP-4) may also recognize other types of sorting signal.
messages: Early endosome
messages: trans-Golgi network membrane

31033:atp2c1
gene id: 31033:atp2c1
uniprot id: H2TYR3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIA subfamily.
messages: Catalyzes the hydrolysis of ATP coupled with the transport of calcium.
messages: Golgi stack membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Monomer. Homodimer.
messages: trans-Golgi network membrane

31033:LOC101062950
gene id: 31033:LOC101062950
uniprot id: H2SM74
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CTL (choline transporter-like) family.
messages: Cell membrane
messages: Choline transporter.
messages: Membrane

31033:vangl2
gene id: 31033:vangl2
uniprot id: H2TJ08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Vang family.
messages: Cell membrane
messages: Membrane

31033:clic4
gene id: 31033:clic4
uniprot id: H2RW98
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel CLIC family.
messages: Cytoplasm
messages: Members of this family may change from a globular, soluble state to a state where the N-terminal domain is inserted into the membrane and functions as chloride channel. A conformation change of the N-terminal domain is thought to expose hydrophobic surfaces that trigger membrane insertion.
messages: Membrane

31033:xrg5
gene id: 31033:xrg5
uniprot id: Q5GH50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XK family.
messages: Membrane

31033:LOC101061591
gene id: 31033:LOC101061591
uniprot id: A0A3B5KKA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM263 family.
messages: Membrane

31033:LOC101072875
gene id: 31033:LOC101072875
uniprot id: H2RX32
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

31033:dll1
gene id: 31033:dll1
uniprot id: A0A674PKL7
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Putative Notch ligand involved in the mediation of Notch signaling.

31033:mmpf1
gene id: 31033:mmpf1
uniprot id: H2S6Q9
names: Similarity
messages: Belongs to the peptidase M10A family.

31033:LOC101073057
gene id: 31033:LOC101073057
uniprot id: H2TZH1
names: Subcellular Location Annotation
messages: Nucleus

31033:LOC101061156
gene id: 31033:LOC101061156
uniprot id: H2RN31
names: Similarity
messages: Belongs to the cyclin family. Cyclin AB subfamily.

31033:enpep
gene id: 31033:enpep
uniprot id: A0A674PGF4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homodimer; disulfide-linked.

31033:st14
gene id: 31033:st14
uniprot id: H2TQ40
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1 family.
messages: Degrades extracellular matrix.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

31033:vps37b
gene id: 31033:vps37b
uniprot id: A0A3B5K2L7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS37 family.
messages: Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in cell growth and differentiation.
messages: Endosome membrane
messages: Late endosome membrane

31033:LOC101078639
gene id: 31033:LOC101078639
uniprot id: A0A3B5KKR4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELO family. ELOVL1 subfamily.
messages: Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that exhibits activity toward saturated C18 to C26 acyl-CoA substrates, with the highest activity towards C22:0 acyl-CoA. May participate to the production of both saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: The C-terminal di-lysine motif may confer endoplasmic reticulum localization.

31033:ppat
gene id: 31033:ppat
uniprot id: H2UTF0
names: Cofactor
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

31033:LOC101069675
gene id: 31033:LOC101069675
uniprot id: A0A674NFH6
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

31033:trarg1
gene id: 31033:trarg1
uniprot id: A0A674PPP2
names: Similarity
messages: Belongs to the CD225/Dispanin family.

31033:LOC101073679
gene id: 31033:LOC101073679
uniprot id: A0A3B5KN04
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the organo anion transporter (TC 2.A.60) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

31033:LOC101075548
gene id: 31033:LOC101075548
uniprot id: A0A6D2X9S2
uniprot id: H2T2X8
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

31033:LOC101079641
gene id: 31033:LOC101079641
uniprot id: Q1KKX1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

31033:LOC101074770
gene id: 31033:LOC101074770
uniprot id: A0A3B5K8L5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.

31033:LOC101067711
gene id: 31033:LOC101067711
uniprot id: Q6E5T0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

31033:lage3
gene id: 31033:lage3
uniprot id: A0A674MQW7
names: Similarity
messages: Belongs to the CTAG/PCC1 family.

31033:cct4
gene id: 31033:cct4
uniprot id: P53451
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TCP-1 chaperonin family.
messages: Component of the chaperonin-containing T-complex (TRiC), a heterooligomeric complex of about 850 to 900 kDa that forms two stacked rings, 12 to 16 nm in diameter.
messages: Component of the chaperonin-containing T-complex (TRiC), a molecular chaperone complex that assists the folding of proteins upon ATP hydrolysis.
messages: Cytoplasm

31033:ube2k
gene id: 31033:ube2k
uniprot id: H2U247
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

31033:apex2
gene id: 31033:apex2
uniprot id: H2USW1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Cytoplasm
messages: Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends.
messages: Mitochondrion
messages: Nucleus
messages: Probably binds two magnesium or manganese ions per subunit.

31033:LOC101067977
gene id: 31033:LOC101067977
uniprot id: A0A3B5JXM2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TFB5 family.
messages: Component of the 7-subunit TFIIH core complex.
messages: In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape.
messages: Nucleus

31033:LOC101076291
gene id: 31033:LOC101076291
uniprot id: A0A3B5K2D4
uniprot id: A0A3B5KJY0
names: Subcellular Location Annotation
messages: extracellular matrix

31033:slc7a14
gene id: 31033:slc7a14
uniprot id: A0A674PQW7
names: Subcellular Location Annotation
messages: Membrane

31033:bbs5
gene id: 31033:bbs5
uniprot id: H2V9K1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BBS5 family.
messages: Membrane
messages: Required for ciliogenesis.
messages: centriolar satellite
messages: cilium membrane

31033:letm2
gene id: 31033:letm2
uniprot id: H2UZA8
names: Subcellular Location Annotation
messages: Membrane

31033:tcf25
gene id: 31033:tcf25
uniprot id: H2VBE3
names: Similarity
messages: Belongs to the TCF25 family.

31033:cd82
gene id: 31033:cd82
uniprot id: H2V399
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

31033:LOC101071223
gene id: 31033:LOC101071223
uniprot id: H2UWA5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the diacylglycerol acyltransferase family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

31033:LOC101063545
gene id: 31033:LOC101063545
uniprot id: H2SNB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family.
messages: Membrane

31033:LOC101064798
gene id: 31033:LOC101064798
uniprot id: A0A674PEN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

31033:ism1
gene id: 31033:ism1
uniprot id: H2RJY6
names: Similarity
messages: Belongs to the isthmin family.

31033:gk
gene id: 31033:gk
uniprot id: H2U3D8
uniprot id: H2U3D9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FGGY kinase family.
messages: Cytoplasm

31033:nup155
gene id: 31033:nup155
uniprot id: Q9DD34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the non-repetitive/WGA-negative nucleoporin family.
messages: nuclear pore complex

31033:LOC101066291
gene id: 31033:LOC101066291
uniprot id: A0A674MJD6
names: Similarity
messages: Belongs to the G-alpha family. G(q) subfamily.

31033:LOC101080058
gene id: 31033:LOC101080058
uniprot id: H2UST2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase subunit 5A family.
messages: Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of a catalytic core of 3 subunits and several supernumerary subunits. The complex exists as a monomer or a dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII).
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
messages: Mitochondrion inner membrane

31033:LOC101068552
gene id: 31033:LOC101068552
uniprot id: A0A674N9G5
names: Similarity
messages: Belongs to the IL-17 family.

31033:LOC101063359
gene id: 31033:LOC101063359
uniprot id: A0A3B5K6E2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

31033:LOC101078976
gene id: 31033:LOC101078976
uniprot id: A0A674NWR6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

31033:LOC101067113
gene id: 31033:LOC101067113
uniprot id: A0A674MEI1
names: Similarity
messages: Belongs to the protein kinase superfamily.

31033:LOC101073508
gene id: 31033:LOC101073508
uniprot id: H2SC68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptophysin/synaptobrevin family.
messages: Membrane

31033:nsg2
gene id: 31033:nsg2
uniprot id: A0A3B5KJN1
names: Similarity
messages: Belongs to the NSG family.

31033:LOC101065316
gene id: 31033:LOC101065316
uniprot id: H2U5R4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

31033:LOC101066520
gene id: 31033:LOC101066520
uniprot id: H2U4H2
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

31033:igfbp3
gene id: 31033:igfbp3
uniprot id: H2U8K6
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

31033:ntf3
gene id: 31033:ntf3
uniprot id: A0A3B5K9Q0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NGF-beta family.
messages: Secreted
messages: Seems to promote the survival of visceral and proprioceptive sensory neurons.

31033:LOC101065389
gene id: 31033:LOC101065389
uniprot id: A0A674PHD6
names: Subcellular Location Annotation
messages: Membrane

31033:foxa1
gene id: 31033:foxa1
uniprot id: H2SR73
names: Subcellular Location Annotation
messages: Nucleus

31033:LOC101074778
gene id: 31033:LOC101074778
uniprot id: H2T307
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

31033:mrpl27
gene id: 31033:mrpl27
uniprot id: A0A674NWS5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

31033:LOC105417999
gene id: 31033:LOC105417999
uniprot id: H2UE10
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

31033:LOC101071639
gene id: 31033:LOC101071639
uniprot id: H2U0I9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IRF family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

31033:rflnb
gene id: 31033:rflnb
uniprot id: H2UXI8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Refilin family.
messages: Interacts with FLNA and FLNB.
messages: cytoskeleton

31033:zar1
gene id: 31033:zar1
uniprot id: Q7T3T9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZAR1 family.
messages: Cytoplasm
messages: Essential for female fertility. May play a role in the oocyte-to-embryo transition (By similarity).

31033:LOC101069150
gene id: 31033:LOC101069150
uniprot id: H2UMX2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the APH-1 family.
messages: Component of the gamma-secretase complex.
messages: Membrane
messages: Potential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral proteins such as Notch receptors.

31033:ints12
gene id: 31033:ints12
uniprot id: H2SKT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Integrator subunit 12 family.
messages: Nucleus

31033:LOC101079885
gene id: 31033:LOC101079885
uniprot id: H2U9Y3
names: Subcellular Location Annotation
messages: Membrane

31033:LOC101068125
gene id: 31033:LOC101068125
uniprot id: A0A674PE30
names: Similarity
messages: Belongs to the protein kinase superfamily.

31033:apoe2
gene id: 31033:apoe2
uniprot id: Q5KST8
names: Similarity
messages: Belongs to the apolipoprotein A1/A4/E family.

31033:LOC101075531
gene id: 31033:LOC101075531
uniprot id: H2TQ24
names: Similarity
messages: Belongs to the protein kinase superfamily.

31033:LOC101063090
gene id: 31033:LOC101063090
uniprot id: A0A674N1B3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

31033:pi4k2a
gene id: 31033:pi4k2a
uniprot id: H2SZK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PI3/PI4-kinase family. Type II PI4K subfamily.
messages: Membrane

31033:grb2
gene id: 31033:grb2
uniprot id: H2T7L9
names: Subcellular Location Annotation
messages: Endosome
messages: Golgi apparatus
messages: Nucleus

31033:nppb
gene id: 31033:nppb
uniprot id: Q805D7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the natriuretic peptide family.
messages: Cardiac hormone which may function as a paracrine antifibrotic factor in the heart. Also plays a key role in cardiovascular homeostasis through natriuresis, diuresis, vasorelaxation, and inhibition of renin and aldosterone secretion. Has a cGMP-stimulating activity (By similarity).
messages: Secreted

31033:rbpj
gene id: 31033:rbpj
uniprot id: A0A674N8J7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Su(H) family.
messages: Nucleus

31033:LOC101069761
gene id: 31033:LOC101069761
uniprot id: H2URM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC24A subfamily.
messages: Membrane

31033:cldn7b
gene id: 31033:cldn7b
uniprot id: Q6E5U0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

31033:LOC101074393
gene id: 31033:LOC101074393
uniprot id: A0A674PDB6
names: Similarity
messages: Belongs to the TACO1 family.

31033:LOC101070984
gene id: 31033:LOC101070984
uniprot id: H2TS81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TDE1 family.
messages: Membrane

31033:c12h1orf43
gene id: 31033:c12h1orf43
uniprot id: H2TN66
names: Function
names: Subcellular Location Annotation
messages: General regulator of phagocytosis. Required to uptake Gram negative bacterium by macrophages.
messages: Golgi apparatus
messages: Membrane
messages: Mitochondrion

31033:dcaf13
gene id: 31033:dcaf13
uniprot id: H2T167
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat DCAF13/WDSOF1 family.
messages: nucleolus

31033:LOC101069498
gene id: 31033:LOC101069498
uniprot id: A0A3B5KPG9
uniprot id: H2SAN7
names: Function
messages: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.

31033:LOC101064501
gene id: 31033:LOC101064501
uniprot id: H2SUM6
names: Similarity
messages: Belongs to the gonadal family.

31033:fmo
gene id: 31033:fmo
uniprot id: Q802T5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FMO family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Microsome membrane

31033:abat
gene id: 31033:abat
uniprot id: A0A3B5K9R2
names: Similarity
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer; disulfide-linked.

31033:LOC101079303
gene id: 31033:LOC101079303
uniprot id: H2V236
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

31033:irf8
gene id: 31033:irf8
uniprot id: H2VBL9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IRF family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

31033:parp16
gene id: 31033:parp16
uniprot id: H2SQF4
names: Similarity
messages: Belongs to the ARTD/PARP family.

31033:LOC101071264
gene id: 31033:LOC101071264
uniprot id: H2TEQ4
names: Similarity
messages: Belongs to the vacuolar ATPase subunit S1 family.

31033:LOC101071456
gene id: 31033:LOC101071456
uniprot id: H2UNH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSC1 (TC 1.A.17) family.
messages: Membrane

31033:LOC101075286
gene id: 31033:LOC101075286
uniprot id: A0A674MRD8
uniprot id: A0A674NHA3
uniprot id: A0A674NU41
names: Similarity
messages: Belongs to the alpha-actinin family.

31033:phox2a
gene id: 31033:phox2a
uniprot id: H2TJR0
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

31033:lypla1
gene id: 31033:lypla1
uniprot id: H2T0D9
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 2 family.

31033:LOC101077956
gene id: 31033:LOC101077956
uniprot id: H2VC05
names: Subcellular Location Annotation
messages: Nucleus

31033:ciao2a
gene id: 31033:ciao2a
uniprot id: A0A674MQG9
names: Similarity
messages: Belongs to the MIP18 family.

31033:LOC101062666
gene id: 31033:LOC101062666
uniprot id: A0A674N787
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

31033:fxn
gene id: 31033:fxn
uniprot id: A0A3B5KW58
names: Similarity
messages: Belongs to the frataxin family.

31033:dpt
gene id: 31033:dpt
uniprot id: A0A3B5K3W6
names: Similarity
messages: Belongs to the dermatopontin family.

31033:LOC101069880
gene id: 31033:LOC101069880
uniprot id: H2TDT0
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

31033:LOC101068259
gene id: 31033:LOC101068259
uniprot id: H2SM96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ASF1 family.
messages: Nucleus

31033:cldn5
gene id: 31033:cldn5
uniprot id: Q6E5U6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

31033:LOC101075984
gene id: 31033:LOC101075984
uniprot id: H2SBF9
names: Subcellular Location Annotation
messages: Membrane

31033:ndufb2
gene id: 31033:ndufb2
uniprot id: H2USX8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFB2 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

31033:bmt2
gene id: 31033:bmt2
uniprot id: H2UXC4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BMT2 family.
messages: Interacts with the GATOR1 complex; interaction is disrupted when BMT2/SAMTOR binds S-adenosyl-L-methionine. Interacts with the KICSTOR complex; interaction is disrupted when BMT2/SAMTOR binds S-adenosyl-L-methionine.
messages: S-adenosyl-L-methionine-binding protein that acts as an inhibitor of mTORC1 signaling via interaction with the GATOR1 and KICSTOR complexes. Acts as a sensor of S-adenosyl-L-methionine to signal methionine sufficiency to mTORC1: in presence of methionine, binds S-adenosyl-L-methionine, leading to disrupt interaction with the GATOR1 and KICSTOR complexes and promote mTORC1 signaling. Upon methionine starvation, S-adenosyl-L-methionine levels are reduced, thereby promoting the association with GATOR1 and KICSTOR, leading to inhibit mTORC1 signaling. Probably also acts as a S-adenosyl-L-methionine-dependent methyltransferase.

31033:LOC101062730
gene id: 31033:LOC101062730
uniprot id: H2TBN4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.

31033:mettl8
gene id: 31033:mettl8
uniprot id: A0A3B5KLH6
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. METL family.
messages: S-adenosyl-L-methionine-dependent methyltransferase.

31033:LOC105418000
gene id: 31033:LOC105418000
uniprot id: A0A3B5KBA3
names: Subcellular Location Annotation
messages: Membrane

31033:lgi1a
gene id: 31033:lgi1a
uniprot id: Q1EGK2
names: Subcellular Location Annotation
messages: Secreted

31033:atp6v1h
gene id: 31033:atp6v1h
uniprot id: H2TWA1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase H subunit family.
messages: Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.

31033:fuz
gene id: 31033:fuz
uniprot id: A0A674P9D0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fuzzy family.
messages: cytoskeleton

31033:LOC101069117
gene id: 31033:LOC101069117
uniprot id: H2SR71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PPP phosphatase family. PP-1 subfamily.
messages: Cytoplasm

31033:isca2
gene id: 31033:isca2
uniprot id: A0A674NQQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HesB/IscA family.
messages: Mitochondrion

31033:tbccd1
gene id: 31033:tbccd1
uniprot id: H2UQB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TBCC family.
messages: centrosome
messages: spindle pole

31033:KEF89 p10
gene id: 31033:KEF89_p10
uniprot id: Q8HCW2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Binds a copper A center.
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
messages: Membrane
messages: Mitochondrion inner membrane

31033:raldh3
gene id: 31033:raldh3
uniprot id: C1PGW5
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

31033:LOC101072197
gene id: 31033:LOC101072197
uniprot id: H2UMM5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Catalyzes the conversion of phosphatidic acid (PA) to CDP-diacylglycerol (CDP-DAG), an essential intermediate in the synthesis of phosphatidylglycerol, cardiolipin and phosphatidylinositol.
messages: Membrane

31033:LOC101068825
gene id: 31033:LOC101068825
uniprot id: H2TD56
names: Function
names: Similarity
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Homodimer.
messages: It is also responsible for the non-negligible production of methylglyoxal a reactive cytotoxic side-product that modifies and can alter proteins, DNA and lipids.
messages: Triosephosphate isomerase is an extremely efficient metabolic enzyme that catalyzes the interconversion between dihydroxyacetone phosphate (DHAP) and D-glyceraldehyde-3-phosphate (G3P) in glycolysis and gluconeogenesis.

31033:LOC101071239
gene id: 31033:LOC101071239
uniprot id: H2V0L3
names: Similarity
messages: Belongs to the intermediate filament family.

31033:LOC101069732
gene id: 31033:LOC101069732
uniprot id: A0A3B5JZ18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic mitochondrial porin family.
messages: Mitochondrion outer membrane

31033:supt20h
gene id: 31033:supt20h
uniprot id: H2RX91
uniprot id: H2RX92
names: Similarity
messages: Belongs to the SPT20 family.

31033:en2
gene id: 31033:en2
uniprot id: H2V9E9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Engrailed homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

31033:cdk5rap3
gene id: 31033:cdk5rap3
uniprot id: H2U2L6
names: Similarity
messages: Belongs to the CDK5RAP3 family.

31033:galnt2
gene id: 31033:galnt2
uniprot id: A0A3B5KG46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

31033:nop16
gene id: 31033:nop16
uniprot id: A0A3B5KFW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOP16 family.
messages: nucleolus

31033:dpy30
gene id: 31033:dpy30
uniprot id: H2U059
names: Similarity
messages: Belongs to the dpy-30 family.

31033:LOC101067851
gene id: 31033:LOC101067851
uniprot id: A0A674MCQ3
names: Subcellular Location Annotation
messages: Membrane

31033:hjv
gene id: 31033:hjv
uniprot id: H2T9J7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the repulsive guidance molecule (RGM) family.
messages: Cell membrane
messages: Membrane

31033:rhpn2
gene id: 31033:rhpn2
uniprot id: A0A674PIX4
names: Similarity
messages: Belongs to the RHPN family.

31033:LOC101075052
gene id: 31033:LOC101075052
uniprot id: A0A674MYK0
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

31033:LOC101073539
gene id: 31033:LOC101073539
uniprot id: A0A674P0G4
uniprot id: H2TA96
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UDPGP type 1 family.
messages: Homooctamer.
messages: UTP--glucose-1-phosphate uridylyltransferase catalyzing the conversion of glucose-1-phosphate into UDP-glucose, a crucial precursor for the production of glycogen.

31033:pacap1b
gene id: 31033:pacap1b
uniprot id: Q5WML0
names: Subcellular Location Annotation
messages: Membrane

31033:LOC101066441
gene id: 31033:LOC101066441
uniprot id: H2UHI7
names: Similarity
messages: Belongs to the inositol phosphokinase (IPK) family.

31033:LOC101079868
gene id: 31033:LOC101079868
uniprot id: Q2PR10
names: Subcellular Location Annotation
messages: Membrane

31033:aif1l
gene id: 31033:aif1l
uniprot id: A0A3B5KL03
names: Subcellular Location Annotation
messages: ruffle membrane

31033:fdps
gene id: 31033:fdps
uniprot id: H2TTF5
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

31033:dimt1
gene id: 31033:dimt1
uniprot id: H2TCE0
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.

31033:LOC101066695
gene id: 31033:LOC101066695
uniprot id: A0A674PKG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

31033:trh
gene id: 31033:trh
uniprot id: H2TW65
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRH family.
messages: Functions as a regulator of the biosynthesis of TSH in the anterior pituitary gland and as a neurotransmitter/ neuromodulator in the central and peripheral nervous systems.
messages: Secreted

31033:cnot11
gene id: 31033:cnot11
uniprot id: H2V2F1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CNOT11 family.
messages: Cytoplasm
messages: Nucleus

31033:LOC101071776
gene id: 31033:LOC101071776
uniprot id: H2SW89
names: Similarity
messages: Belongs to the phosphatase 2A regulatory subunit B family.

31033:atp10d
gene id: 31033:atp10d
uniprot id: H2SCQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

31033:rhag-2
gene id: 31033:rhag-2
uniprot id: Q7T3R7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonium transporter (TC 2.A.49) family. Rh subfamily.
messages: Cell membrane
messages: Functions as an ammonia transporter. May play a role in the elimination of ammonia in the gill.
messages: Membrane

31033:LOC101071046
gene id: 31033:LOC101071046
uniprot id: A0A3B5KLK6
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

31033:LOC101063282
gene id: 31033:LOC101063282
uniprot id: A0A3B5KK94
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

31033:LOC101073906
gene id: 31033:LOC101073906
uniprot id: A0A3B5KI81
names: Subcellular Location Annotation
messages: extracellular space

31033:fgfbp1
gene id: 31033:fgfbp1
uniprot id: H2SWM7
names: Similarity
messages: Belongs to the fibroblast growth factor-binding protein family.

31033:slc2a4
gene id: 31033:slc2a4
uniprot id: H2TZU8
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

31033:alx1
gene id: 31033:alx1
uniprot id: H2U5A6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

31033:tmem57
gene id: 31033:tmem57
uniprot id: Q2TLY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the macoilin family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Nucleus membrane
messages: Rough endoplasmic reticulum membrane

31033:irak1bp1
gene id: 31033:irak1bp1
uniprot id: H2RSG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IRAK1BP1 family.
messages: Cytoplasm
messages: Nucleus

31033:polr3a
gene id: 31033:polr3a
uniprot id: H2UBT0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Component of the RNA polymerase III (Pol III) complex consisting of 17 subunits.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Nucleus

31033:ctps1
gene id: 31033:ctps1
uniprot id: H2TJ57
names: Function
names: Similarity
messages: Belongs to the CTP synthase family.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.

31033:crbn
gene id: 31033:crbn
uniprot id: A0A3B5KIU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CRBN family.
messages: Nucleus

31033:LOC101077379
gene id: 31033:LOC101077379
uniprot id: H2RUL2
names: Similarity
messages: Belongs to the ubiquitin family.

31033:LOC101080202
gene id: 31033:LOC101080202
uniprot id: H2SLJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC35F solute transporter family.
messages: Membrane

31033:fbxo32
gene id: 31033:fbxo32
uniprot id: H2SIP1
names: Subcellular Location Annotation
messages: Nucleus

31033:unk
gene id: 31033:unk
uniprot id: H2SZ51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unkempt family.
messages: Cytoplasm

31033:sbf2
gene id: 31033:sbf2
uniprot id: H2V622
uniprot id: H2V623
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.

31033:LOC101062691
gene id: 31033:LOC101062691
uniprot id: H2SSP1
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. GSK-3 subfamily.

31033:gprc6a
gene id: 31033:gprc6a
uniprot id: H2SYE2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

31033:LOC101078836
gene id: 31033:LOC101078836
uniprot id: A0A674N5L3
names: Subcellular Location Annotation
messages: Membrane

31033:LOC101080050
gene id: 31033:LOC101080050
uniprot id: H2U9C5
names: Function
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
messages: May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway.

31033:gabpa
gene id: 31033:gabpa
uniprot id: H2TQW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

31033:galk1
gene id: 31033:galk1
uniprot id: H2T403
uniprot id: H2T406
names: Similarity
messages: Belongs to the GHMP kinase family. GalK subfamily.

31033:LOC101067984
gene id: 31033:LOC101067984
uniprot id: H2ULJ5
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pentraxin family.
messages: Binds 2 calcium ions per subunit.
messages: Homopentamer. Pentaxin (or pentraxin) have a discoid arrangement of 5 non-covalently bound subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

31033:LOC101070704
gene id: 31033:LOC101070704
uniprot id: A0A674NE11
names: Similarity
messages: Belongs to the phosphohexose mutase family.

31033:hoxd12
gene id: 31033:hoxd12
uniprot id: H2V6V6
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

31033:gng3
gene id: 31033:gng3
uniprot id: H2RUY9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

31033:dennd11
gene id: 31033:dennd11
uniprot id: A0A3B5KNA8
names: Similarity
messages: Belongs to the DENND11 family.

31033:rad17
gene id: 31033:rad17
uniprot id: A0A3B5KL10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rad17/RAD24 family.
messages: Nucleus

31033:LOC101072610
gene id: 31033:LOC101072610
uniprot id: H2SL72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

31033:LOC101078979
gene id: 31033:LOC101078979
uniprot id: H2UZV0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with GIRK2, GIRK3 or GIRK4 to form a G-protein activated heteromultimer pore-forming unit. The resulting inward current is much larger.
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family. KCNJ3 subfamily.
messages: Membrane
messages: This potassium channel is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. This receptor plays a crucial role in regulating the heartbeat.

31033:LOC101064836
gene id: 31033:LOC101064836
uniprot id: H2USX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Deltex family.
messages: Cytoplasm

31033:LOC101073763
gene id: 31033:LOC101073763
uniprot id: A0A674PE77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Membrane

31033:sfrp5
gene id: 31033:sfrp5
uniprot id: A0A3B5K2E6
names: Caution
names: Similarity
messages: Belongs to the secreted frizzled-related protein (sFRP) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

31033:mcm4
gene id: 31033:mcm4
uniprot id: H2T1R4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.
messages: Belongs to the MCM family.
messages: Chromosome
messages: Component of the MCM2-7 complex.
messages: Nucleus

31033:cwf19l2
gene id: 31033:cwf19l2
uniprot id: H2SZG5
names: Similarity
messages: Belongs to the CWF19 family.

31033:phpt1
gene id: 31033:phpt1
uniprot id: A0A3B5K405
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the janus family.
messages: Cytoplasm
messages: Exhibits phosphohistidine phosphatase activity.
messages: Monomer.

31033:LOC105417793
gene id: 31033:LOC105417793
uniprot id: A0A3B5K0S8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylin family.
messages: Secreted

31033:bsg
gene id: 31033:bsg
uniprot id: H2VAM3
names: Subcellular Location Annotation
messages: Basolateral cell membrane
messages: Cell membrane
messages: Endoplasmic reticulum membrane
messages: Lateral cell membrane

31033:lum
gene id: 31033:lum
uniprot id: H2UDG2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class II subfamily.
messages: Binds to laminin.
messages: extracellular matrix

31033:cs
gene id: 31033:cs
uniprot id: H2UPT3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the citrate synthase family.
messages: Homodimer.
messages: Mitochondrion matrix

31033:LOC101077879
gene id: 31033:LOC101077879
uniprot id: H2UUB5
names: Subcellular Location Annotation
messages: Membrane

31033:LOC101061939
gene id: 31033:LOC101061939
uniprot id: Q6IEH9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

31033:LOC101076381
gene id: 31033:LOC101076381
uniprot id: H2TSK5
names: Similarity
names: Subunit
messages: Belongs to the GILT family.
messages: Dimer; disulfide-linked.

31033:LOC101079162
gene id: 31033:LOC101079162
uniprot id: A0A3B5K970
names: Similarity
messages: Belongs to the CDI family.

31033:ppme1
gene id: 31033:ppme1
uniprot id: H2UIT3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the AB hydrolase superfamily.
messages: Binds PPP2CA and PPP2CB.
messages: Demethylates proteins that have been reversibly carboxymethylated. Demethylates PPP2CB (in vitro) and PPP2CA. Binding to PPP2CA displaces the manganese ion and inactivates the enzyme.

31033:hhat
gene id: 31033:hhat
uniprot id: A0A674NTM8
names: Subcellular Location Annotation
messages: Membrane

31033:LOC101063088
gene id: 31033:LOC101063088
uniprot id: H2UYP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dynein light chain family.
messages: cytoskeleton

31033:sf3b6
gene id: 31033:sf3b6
uniprot id: A0A3B5JWG7
names: Subcellular Location Annotation
messages: Nucleus

31033:LOC778011
gene id: 31033:LOC778011
uniprot id: Q9IAH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
messages: Membrane
messages: photoreceptor outer segment

31033:plxna4
gene id: 31033:plxna4
uniprot id: A0A674PRM1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the plexin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

31033:e2f3
gene id: 31033:e2f3
uniprot id: A0A3B5K1B2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the E2F/DP family.
messages: Nucleus

31033:LOC101066950
gene id: 31033:LOC101066950
uniprot id: H2SY89
names: Similarity
messages: Belongs to the adaptor complexes large subunit family.

31033:LOC101074783
gene id: 31033:LOC101074783
uniprot id: H2VEW0
names: Similarity
messages: Belongs to the PPP phosphatase family. PP-2B subfamily.

31033:LOC101071428
gene id: 31033:LOC101071428
uniprot id: A0A674MHR9
names: Function
names: Similarity
messages: Belongs to the parvalbumin family.
messages: In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions.

31033:ivd
gene id: 31033:ivd
uniprot id: H2U8G6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

31033:LOC101074561
gene id: 31033:LOC101074561
uniprot id: A0A3B5JXG8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

31033:LOC445936
gene id: 31033:LOC445936
uniprot id: H2TEJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Nucleus

31033:zdhhc9
gene id: 31033:zdhhc9
uniprot id: H2TW56
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family. ERF2/ZDHHC9 subfamily.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

31033:LOC101064540
gene id: 31033:LOC101064540
uniprot id: H2RT39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

31033:ctsd2
gene id: 31033:ctsd2
uniprot id: Q5TLU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A1 family.
messages: Lysosome

31033:enpp5
gene id: 31033:enpp5
uniprot id: H2RMA5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide pyrophosphatase/phosphodiesterase family.
messages: Cell membrane
messages: Hydrolyzes extracellular Ap3A into AMP and ADP, and Ap4A into AMP and ATP. Ap3A and Ap4A are diadenosine polyphosphates thought to induce proliferation of vascular smooth muscle cells. Acts as a procoagulant, mediating platelet aggregation at the site of nascent thrombus via release of ADP from Ap3A and activation of ADP receptors.
messages: Membrane

31033:mif
gene id: 31033:mif
uniprot id: Q5I4D1
names: Similarity
messages: Belongs to the MIF family.

31033:cdh18
gene id: 31033:cdh18
uniprot id: A0A674MQU2
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

31033:LOC101079915
gene id: 31033:LOC101079915
uniprot id: Q6E5R7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

31033:ttc4
gene id: 31033:ttc4
uniprot id: H2VE81
names: Similarity
messages: Belongs to the TTC4 family.

31033:snapin
gene id: 31033:snapin
uniprot id: H2SB13
names: Similarity
messages: Belongs to the SNAPIN family.

31033:slc17a5
gene id: 31033:slc17a5
uniprot id: A0A674NKY2
names: Subcellular Location Annotation
messages: Membrane

31033:LOC101076406
gene id: 31033:LOC101076406
uniprot id: H2URS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

31033:LOC101067011
gene id: 31033:LOC101067011
uniprot id: H2U445
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family. KCNJ2 subfamily.
messages: Membrane

31033:cript
gene id: 31033:cript
uniprot id: H2SG76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CRIPT family.
messages: Cytoplasm

31033:LOC101069099
gene id: 31033:LOC101069099
uniprot id: H2RK05
names: Similarity
messages: Belongs to the WD repeat G protein beta family.

31033:LOC101071755
gene id: 31033:LOC101071755
uniprot id: H2TJZ1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the InsP3 receptor family.
messages: Endoplasmic reticulum membrane
messages: Homotetramer.
messages: Membrane
messages: Receptor for inositol 1,4,5-trisphosphate, a second messenger that mediates the release of intracellular calcium.
messages: The receptor contains a calcium channel in its C-terminal extremity. Its large N-terminal cytoplasmic region has the ligand-binding site in the N-terminus and modulatory sites in the middle portion immediately upstream of the channel region.

31033:LOC101069540
gene id: 31033:LOC101069540
uniprot id: A0A674NL63
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular space

31033:LOC101076705
gene id: 31033:LOC101076705
uniprot id: A0A3B5K9X2
names: Similarity
messages: Belongs to the SLITRK family.

31033:LOC101076653
gene id: 31033:LOC101076653
uniprot id: H2UW36
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

31033:LOC101072272
gene id: 31033:LOC101072272
uniprot id: H2RXC6
names: Similarity
messages: Belongs to the PDCD4 family.

31033:LOC101078446
gene id: 31033:LOC101078446
uniprot id: H2TCV9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit C family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
messages: Cytoplasm

31033:LOC101065469
gene id: 31033:LOC101065469
uniprot id: A0A3B5KFK5
names: Subcellular Location Annotation
messages: Nucleus

31033:taf6l
gene id: 31033:taf6l
uniprot id: H2U5H1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF6 family.
messages: Nucleus

31033:mrgbp
gene id: 31033:mrgbp
uniprot id: H2SRW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EAF7 family.
messages: Nucleus

31033:ddit4
gene id: 31033:ddit4
uniprot id: A0A674MVU3
names: Similarity
messages: Belongs to the DDIT4 family.

31033:LOC101067051
gene id: 31033:LOC101067051
uniprot id: A0A173MRX2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycoprotein hormones subunit beta family.
messages: Heterodimer of an alpha and a beta chain.
messages: Involved in gametogenesis and steroidogenesis.
messages: Secreted

31033:LOC101070764
gene id: 31033:LOC101070764
uniprot id: A0A674MCT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CYRI family.
messages: Membrane

31033:KEF89 p09
gene id: 31033:KEF89_p09
uniprot id: Q8HCW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase protein 8 family.
messages: Membrane
messages: Mitochondrion membrane

31033:coq2
gene id: 31033:coq2
uniprot id: H2V1S6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family.
messages: Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate.
messages: Mitochondrion inner membrane

31033:LOC101076023
gene id: 31033:LOC101076023
uniprot id: H2TQJ6
names: Similarity
messages: Belongs to the DeSI family.

31033:prpf31
gene id: 31033:prpf31
uniprot id: A0A674PAL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRP31 family.
messages: Cajal body

31033:LOC101063521
gene id: 31033:LOC101063521
uniprot id: H2SH61
names: Similarity
names: Subunit
messages: Belongs to the histone H3 family.
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

31033:tcp1
gene id: 31033:tcp1
uniprot id: H2SQ27
names: Similarity
messages: Belongs to the TCP-1 chaperonin family.

31033:nell2
gene id: 31033:nell2
uniprot id: A0A674NFJ9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

31033:smpd2
gene id: 31033:smpd2
uniprot id: A0A674PJ17
names: Similarity
messages: Belongs to the neutral sphingomyelinase family.

31033:b4galt4
gene id: 31033:b4galt4
uniprot id: H2V221
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 7 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids.

31033:btk
gene id: 31033:btk
uniprot id: Q90YI6
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

31033:LOC101064246
gene id: 31033:LOC101064246
uniprot id: H2S2P8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small heat shock protein (HSP20) family.
messages: Cytoplasm

31033:LOC101073009
gene id: 31033:LOC101073009
uniprot id: H2TQ88
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UQCRB/QCR7 family.
messages: Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation.
messages: Mitochondrion inner membrane

31033:laptm4b
gene id: 31033:laptm4b
uniprot id: H2TQ71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LAPTM4/LAPTM5 transporter family.
messages: Cell membrane
messages: Endomembrane system
messages: Endosome membrane
messages: Late endosome membrane
messages: Membrane
messages: multivesicular body lumen
messages: multivesicular body membrane

31033:LOC101070981
gene id: 31033:LOC101070981
uniprot id: H2SZ21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STOP family.
messages: cytoskeleton

31033:ccr10
gene id: 31033:ccr10
uniprot id: D6RRB8
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

31033:ppp1r14c
gene id: 31033:ppp1r14c
uniprot id: A0A3B5K7H1
names: Similarity
messages: Belongs to the PP1 inhibitor family.

31033:cav1
gene id: 31033:cav1
uniprot id: A0A3B5KAY2
uniprot id: Q9YGM8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the caveolin family.
messages: Cell membrane
messages: Golgi apparatus membrane
messages: Homooligomer.
messages: May act as a positive regulator of T-cell coactivation. May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity).
messages: May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity.
messages: Membrane
messages: Membrane raft
messages: caveola

31033:unc119b
gene id: 31033:unc119b
uniprot id: H2UWX9
names: Similarity
messages: Belongs to the PDE6D/unc-119 family.

31033:hspa5
gene id: 31033:hspa5
uniprot id: H2S609
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heat shock protein 70 family.
messages: Endoplasmic reticulum lumen

31033:LOC101075516
gene id: 31033:LOC101075516
uniprot id: A0A674NKC8
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL19 family.
messages: Component of the large ribosomal subunit.

31033:pea15
gene id: 31033:pea15
uniprot id: H2SKB5
names: Subcellular Location Annotation
messages: Cytoplasm

31033:fis1
gene id: 31033:fis1
uniprot id: A0A674NJ41
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FIS1 family.
messages: Involved in the fragmentation of the mitochondrial network and its perinuclear clustering.
messages: Membrane
messages: Mitochondrion outer membrane
messages: The C-terminus is required for mitochondrial localization, while the N-terminus is necessary for mitochondrial fission.

31033:LOC101074499
gene id: 31033:LOC101074499
uniprot id: H2SQS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ITM2 family.
messages: Membrane

31033:LOC101074740
gene id: 31033:LOC101074740
uniprot id: H2UNR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

31033:slc35e2b
gene id: 31033:slc35e2b
uniprot id: A0A3B5KAV4
names: Subcellular Location Annotation
messages: Membrane

31033:nfya
gene id: 31033:nfya
uniprot id: H2SA39
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NFYA/HAP2 subunit family.
messages: Component of the sequence-specific heterotrimeric transcription factor (NF-Y) which specifically recognizes a 5'-CCAAT-3' box motif found in the promoters of its target genes.
messages: Heterotrimer.
messages: Nucleus

31033:myc
gene id: 31033:myc
uniprot id: H2TBQ9
uniprot id: Q3LFR6
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Efficient DNA binding requires dimerization with another bHLH protein. Binds DNA as a heterodimer with MAX.
messages: Nucleus
messages: Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes.

31033:rplp0
gene id: 31033:rplp0
uniprot id: H2UUC0
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Ribosomal protein P0 is the functional equivalent of E.coli protein L10.

31033:phkg2
gene id: 31033:phkg2
uniprot id: H2UTA4
names: Similarity
names: Subunit
messages: Belongs to the protein kinase superfamily.
messages: Hexadecamer of 4 heterotetramers, each composed of alpha, beta, gamma, and delta subunits. Alpha (PHKA1 or PHKA2) and beta (PHKB) are regulatory subunits, gamma (PHKG1 or PHKG2) is the catalytic subunit, and delta is calmodulin.

31033:LOC105416477
gene id: 31033:LOC105416477
uniprot id: A0A3B5KA49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the actinoporin family. Sea anemone subfamily.
messages: Cell membrane
messages: Membrane
messages: Nematocyst
messages: Target cell membrane

31033:LOC101064797
gene id: 31033:LOC101064797
uniprot id: H2V9T0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

31033:psma1
gene id: 31033:psma1
uniprot id: H2TCF6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. Associated with two 19S regulatory particles, forms the 26S proteasome and thus participates in the ATP-dependent degradation of ubiquitinated proteins. The 26S proteasome plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins that could impair cellular functions, and by removing proteins whose functions are no longer required. Associated with the PA200 or PA28, the 20S proteasome mediates ubiquitin-independent protein degradation. This type of proteolysis is required in several pathways including spermatogenesis (20S-PA200 complex) or generation of a subset of MHC class I-presented antigenic peptides (20S-PA28 complex).
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.

31033:ppp2r5e
gene id: 31033:ppp2r5e
uniprot id: A0A674PGU3
names: Similarity
messages: Belongs to the phosphatase 2A regulatory subunit B56 family.

31033:negr1
gene id: 31033:negr1
uniprot id: A0A674MA17
uniprot id: A0A674NCQ1
uniprot id: A0A674PPC7
names: Subcellular Location Annotation
messages: Membrane

31033:crh
gene id: 31033:crh
uniprot id: H2TBH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sauvagine/corticotropin-releasing factor/urotensin I family.
messages: Secreted

31033:LOC101079790
gene id: 31033:LOC101079790
uniprot id: H2V6I3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Interacts with HDAC7 and KAT5.
messages: Membrane
messages: Receptor for endothelin-1. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of binding affinities for ET-A is: ET1 > ET2 >> ET3.

31033:LOC101075774
gene id: 31033:LOC101075774
uniprot id: A0A3B5K6W9
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Associates with the cytoplasmic CCR4-NOT deadenylase complex to trigger ARE-containing mRNA deadenylation and decay processes.
messages: Cytoplasm
messages: Nucleus
messages: Zinc-finger RNA-binding protein that destabilizes several cytoplasmic AU-rich element (ARE)-containing mRNA transcripts by promoting their poly(A) tail removal or deadenylation, and hence provide a mechanism for attenuating protein synthesis. Acts as a 3'-untranslated region (UTR) ARE mRNA-binding adapter protein to communicate signaling events to the mRNA decay machinery. Functions by recruiting the CCR4-NOT deadenylase complex and probably other components of the cytoplasmic RNA decay machinery to the bound ARE-containing mRNAs, and hence promotes ARE-mediated mRNA deadenylation and decay processes. Binds to 3'-UTR ARE of numerous mRNAs.

31033:rprd1b
gene id: 31033:rprd1b
uniprot id: A0A3B5KHG1
uniprot id: H2UTG3
names: Similarity
messages: Belongs to the UPF0400 (RTT103) family.

31033:LOC101079358
gene id: 31033:LOC101079358
uniprot id: A0A3B5KLI8
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

31033:ube4a
gene id: 31033:ube4a
uniprot id: H2UR99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ubiquitin conjugation factor E4 family.
messages: Cytoplasm

31033:LOC101062757
gene id: 31033:LOC101062757
uniprot id: H2SPE5
names: Subcellular Location Annotation
messages: Membrane
messages: cytoskeleton

31033:LOC101071997
gene id: 31033:LOC101071997
uniprot id: H2TFT5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Rab GDI family.
messages: Cytoplasm
messages: Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP.

31033:cachd1
gene id: 31033:cachd1
uniprot id: A0A3B5KEN1
names: Similarity
messages: Belongs to the calcium channel subunit alpha-2/delta family.

31033:LOC101061231
gene id: 31033:LOC101061231
uniprot id: H2TIV2
names: Similarity
messages: Belongs to the GST superfamily.

31033:cdkal1
gene id: 31033:cdkal1
uniprot id: H2T817
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. CDKAL1 subfamily.
messages: Binds 1 or 2 [4Fe-4S] cluster. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-threonylcarbamoyladenosine (t(6)A), leading to the formation of 2-methylthio-N6-threonylcarbamoyladenosine (ms(2)t(6)A) at position 37 in tRNAs that read codons beginning with adenine.
messages: Endoplasmic reticulum membrane

31033:LOC101063197
gene id: 31033:LOC101063197
uniprot id: H2SL37
names: Similarity
messages: Belongs to the yippee family.

31033:LOC101078823
gene id: 31033:LOC101078823
uniprot id: A0A3B5KDP3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

31033:cdc5l
gene id: 31033:cdc5l
uniprot id: A0A3B5K703
names: Similarity
messages: Belongs to the CEF1 family.

31033:scoc
gene id: 31033:scoc
uniprot id: A0A674MMN8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCOC family.
messages: Positive regulator of amino acid starvation-induced autophagy.
messages: trans-Golgi network

31033:dlx1
gene id: 31033:dlx1
uniprot id: H2V8E3
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

31033:LOC101068776
gene id: 31033:LOC101068776
uniprot id: H2TEM6
names: Similarity
messages: Belongs to the GST superfamily. Theta family.

31033:LOC101067091
gene id: 31033:LOC101067091
uniprot id: H2UFT0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

31033:pou3f4
gene id: 31033:pou3f4
uniprot id: H2TCY2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family. Class-3 subfamily.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

31033:LOC101078280
gene id: 31033:LOC101078280
uniprot id: H2SZZ3
names: Similarity
messages: Belongs to the RRM elav family.

31033:foxf1
gene id: 31033:foxf1
uniprot id: A0A674NVF1
names: Subcellular Location Annotation
messages: Nucleus

31033:LOC101071051
gene id: 31033:LOC101071051
uniprot id: H2V532
names: Similarity
messages: Belongs to the nucleobindin family.

31033:LOC101070283
gene id: 31033:LOC101070283
uniprot id: H2TB62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glucagon family.
messages: Secreted

31033:rln3b
gene id: 31033:rln3b
uniprot id: Q0GY48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the insulin family.
messages: Secreted

31033:LOC101077970
gene id: 31033:LOC101077970
uniprot id: H2U7N2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAGUK family.
messages: Cell membrane
messages: Membrane
messages: tight junction

31033:zranb2
gene id: 31033:zranb2
uniprot id: H2S5N7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZRANB2 family.
messages: May interfere with constitutive 5'-splice site selection.
messages: Nucleus

31033:LOC100653420
gene id: 31033:LOC100653420
uniprot id: E9LZ01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prominin family.
messages: Membrane
messages: microvillus membrane

31033:LOC101079822
gene id: 31033:LOC101079822
uniprot id: Q1KKZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

31033:rpn2
gene id: 31033:rpn2
uniprot id: A0A674PLT1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SWP1 family.
messages: Component of the oligosaccharyltransferase (OST) complex.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.

31033:nck1
gene id: 31033:nck1
uniprot id: H2V8B5
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Endoplasmic reticulum

31033:hpgd
gene id: 31033:hpgd
uniprot id: A0A3B5K0R0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

31033:st6galnac6
gene id: 31033:st6galnac6
uniprot id: A0A674PH18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

31033:LOC101064478
gene id: 31033:LOC101064478
uniprot id: A0A3B5K713
names: Subcellular Location Annotation
messages: Mitochondrion

31033:runx1
gene id: 31033:runx1
uniprot id: A0A9N7
uniprot id: Q642Y3
names: Subcellular Location Annotation
messages: Nucleus

31033:LOC101072191
gene id: 31033:LOC101072191
uniprot id: A0A674MWB9
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

31033:mbtd1
gene id: 31033:mbtd1
uniprot id: H2SQS6
names: Subcellular Location Annotation
messages: Nucleus

31033:fzd4
gene id: 31033:fzd4
uniprot id: H2SSV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor Fz/Smo family.
messages: Membrane

31033:atp8b1
gene id: 31033:atp8b1
uniprot id: A0A674MCK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

31033:st3gal3
gene id: 31033:st3gal3
uniprot id: H2T264
uniprot id: Q702S0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

31033:mrps16
gene id: 31033:mrps16
uniprot id: A0A674NFC3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

31033:icmt
gene id: 31033:icmt
uniprot id: H2T8D8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class VI-like SAM-binding methyltransferase superfamily. Isoprenylcysteine carboxyl methyltransferase family.
messages: Catalyzes the post-translational methylation of isoprenylated C-terminal cysteine residues.
messages: Endoplasmic reticulum membrane
messages: Membrane

31033:cldn33b
gene id: 31033:cldn33b
uniprot id: Q6E5P3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

31033:ghsr
gene id: 31033:ghsr
uniprot id: H2U752
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for ghrelin, coupled to G-alpha-11 proteins. Stimulates growth hormone secretion. Binds also other growth hormone releasing peptides (GHRP) (e.g. Met-enkephalin and GHRP-6) as well as non-peptide, low molecular weight secretagogues (e.g. L-692,429, MK-0677, adenosine).

31033:psmc4
gene id: 31033:psmc4
uniprot id: A0A674PCB6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. PSMC4 belongs to the heterohexameric ring of AAA (ATPases associated with diverse cellular activities) proteins that unfolds ubiquitinated target proteins that are concurrently translocated into a proteolytic chamber and degraded into peptides.
messages: Cytoplasm

31033:LOC101066073
gene id: 31033:LOC101066073
uniprot id: H2RK12
names: Similarity
messages: Belongs to the STXBP/unc-18/SEC1 family.

31033:LOC101068302
gene id: 31033:LOC101068302
uniprot id: A0A3B5K545
names: Cofactor
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS27 family.
messages: Binds 1 zinc ion per subunit.

31033:cdk2ap2
gene id: 31033:cdk2ap2
uniprot id: A0A674NH37
names: Similarity
messages: Belongs to the CDK2AP family.

31033:mis18a
gene id: 31033:mis18a
uniprot id: A0A674MEP0
uniprot id: A0A674MKS9
names: Function
names: Subcellular Location Annotation
messages: Required for recruitment of CENPA to centromeres and normal chromosome segregation during mitosis.
messages: centromere

31033:LOC101065152
gene id: 31033:LOC101065152
uniprot id: A0A6D2XZU8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for the neuromedin-U and neuromedin-S neuropeptides.

31033:pggt1b
gene id: 31033:pggt1b
uniprot id: A0A674NPU9
names: Similarity
messages: Belongs to the protein prenyltransferase subunit beta family.

31033:vangl1
gene id: 31033:vangl1
uniprot id: H2S8F4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Vang family.
messages: Cell membrane
messages: Membrane

31033:mknk2
gene id: 31033:mknk2
uniprot id: A0A674N8L9
names: Similarity
messages: Belongs to the protein kinase superfamily.

31033:rln
gene id: 31033:rln
uniprot id: Q0GY47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the insulin family.
messages: Secreted

31033:zbtb8os
gene id: 31033:zbtb8os
uniprot id: A0A3B5K6N6
names: Similarity
names: Subunit
messages: Belongs to the archease family.
messages: Component of the tRNA-splicing ligase complex.

31033:LOC101072119
gene id: 31033:LOC101072119
uniprot id: Q6E5Q0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

31033:slc25a11
gene id: 31033:slc25a11
uniprot id: A0A3B5KF06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

31033:ube2a
gene id: 31033:ube2a
uniprot id: A0A674PRE2
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

31033:LOC101076921
gene id: 31033:LOC101076921
uniprot id: H2RRP4
names: Similarity
messages: Belongs to the arrestin family.

31033:gria1
gene id: 31033:gria1
uniprot id: A0A674MT32
uniprot id: A0A674NB68
names: Subcellular Location Annotation
messages: Membrane

31033:npc1l1
gene id: 31033:npc1l1
uniprot id: H2SIS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the patched family.
messages: Membrane

31033:tspan7
gene id: 31033:tspan7
uniprot id: H2TGZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

31033:LOC101070302
gene id: 31033:LOC101070302
uniprot id: H2S7P7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

31033:tlr3
gene id: 31033:tlr3
uniprot id: A0A3B5K0I8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Toll-like receptor family.
messages: Membrane

31033:pth2r
gene id: 31033:pth2r
uniprot id: Q2UZQ9
names: Subcellular Location Annotation
messages: Membrane

31033:rpl22l1
gene id: 31033:rpl22l1
uniprot id: H2S4R5
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL22 family.

31033:smc3
gene id: 31033:smc3
uniprot id: Q802S0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMC family. SMC3 subfamily.
messages: Central component of cohesin, a complex required for chromosome cohesion during the cell cycle. The cohesin complex may form a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. Cohesion is coupled to DNA replication and is involved in DNA repair. The cohesin complex also plays an important role in spindle pole assembly during mitosis and in chromosomes movement.
messages: Nucleus
messages: centromere

31033:LOC101064643
gene id: 31033:LOC101064643
uniprot id: H2UQQ0
names: Similarity
messages: Belongs to the GTP cyclohydrolase I family.

31033:LOC101068481
gene id: 31033:LOC101068481
uniprot id: H2U7B3
names: Similarity
messages: Belongs to the Gfo/Idh/MocA family.

31033:cldn29b
gene id: 31033:cldn29b
uniprot id: Q6E5R6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

31033:ndrg3
gene id: 31033:ndrg3
uniprot id: A0A674PF38
uniprot id: H2TQ50
names: Similarity
messages: Belongs to the NDRG family.

31033:LOC101068749
gene id: 31033:LOC101068749
uniprot id: A0A3B5K164
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PNRC family. PNRC2 subfamily.
messages: Nucleus
messages: P-body

31033:kdelr3
gene id: 31033:kdelr3
uniprot id: A0A3B5KJQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERD2 family.
messages: COPI-coated vesicle membrane
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Membrane

31033:LOC101061816
gene id: 31033:LOC101061816
uniprot id: H2TQ81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family.
messages: Membrane

31033:tert
gene id: 31033:tert
uniprot id: H2UH84
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the reverse transcriptase family. Telomerase subfamily.
messages: Nucleus
messages: Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme.
messages: telomere

31033:LOC101075730
gene id: 31033:LOC101075730
uniprot id: H2SJY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Perikaryon
messages: axon
messages: dendrite

31033:lfng
gene id: 31033:lfng
uniprot id: H2UGK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

31033:cdk5rap1
gene id: 31033:cdk5rap1
uniprot id: A0A674P510
names: Similarity
messages: Belongs to the methylthiotransferase family. MiaB subfamily.

31033:itpk1
gene id: 31033:itpk1
uniprot id: H2T0A5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ITPK1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Kinase that can phosphorylate various inositol polyphosphate such as Ins(3,4,5,6)P4 or Ins(1,3,4)P3.
messages: Monomer.

31033:LOC101064398
gene id: 31033:LOC101064398
uniprot id: A0A3B5K0G0
names: Subcellular Location Annotation
messages: Membrane

31033:LOC101071237
gene id: 31033:LOC101071237
uniprot id: H2UTZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C26 family.
messages: extracellular space

31033:nt5c2
gene id: 31033:nt5c2
uniprot id: A0A674MYM4
names: Cofactor
names: Similarity
messages: Belongs to the 5'(3')-deoxyribonucleotidase family.
messages: Binds 1 Mg(2+) ion per subunit.

31033:rfc2
gene id: 31033:rfc2
uniprot id: H2TJS8
names: Similarity
messages: Belongs to the activator 1 small subunits family.

31033:LOC101068230
gene id: 31033:LOC101068230
uniprot id: H2UEE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
messages: Nucleus

31033:ppm1k
gene id: 31033:ppm1k
uniprot id: H2U271
names: Similarity
messages: Belongs to the PP2C family.

31033:hmx2
gene id: 31033:hmx2
uniprot id: H2RR99
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

31033:LOC101063989
gene id: 31033:LOC101063989
uniprot id: H2RWU2
names: Similarity
messages: Belongs to the cytochrome P450 family.

31033:map3k10
gene id: 31033:map3k10
uniprot id: A0A674N9U5
names: Activity Regulation
names: Similarity
names: Subunit
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.
messages: Homodimer.
messages: Homodimerization via the leucine zipper domains is required for autophosphorylation.

31033:zcchc17
gene id: 31033:zcchc17
uniprot id: H2U9W2
names: Subcellular Location Annotation
messages: nucleolus

31033:emc8
gene id: 31033:emc8
uniprot id: A0A674PC67
names: Similarity
messages: Belongs to the EMC8/EMC9 family.

31033:cldn28a
gene id: 31033:cldn28a
uniprot id: Q6E5Q4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

31033:rrp7a
gene id: 31033:rrp7a
uniprot id: A0A3B5KCP9
names: Similarity
messages: Belongs to the RRP7 family.

31033:LOC101063872
gene id: 31033:LOC101063872
uniprot id: A0A3B5K7M9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM53 family.
messages: Membrane
messages: Nucleus outer membrane

31033:LOC101078862
gene id: 31033:LOC101078862
uniprot id: A0A674MYD8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1 family. Plasminogen subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular space

31033:katnb1
gene id: 31033:katnb1
uniprot id: H2S9V8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat KATNB1 family.
messages: Cytoplasm
messages: Interacts with KATNA1. This interaction enhances the microtubule binding and severing activity of KATNA1 and also targets this activity to the centrosome.
messages: Participates in a complex which severs microtubules in an ATP-dependent manner. May act to target the enzymatic subunit of this complex to sites of action such as the centrosome. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation.
messages: centrosome
messages: cytoskeleton
messages: spindle
messages: spindle pole

31033:adora2a
gene id: 31033:adora2a
uniprot id: A0A674MC46
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.

31033:vps33b
gene id: 31033:vps33b
uniprot id: H2UJI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STXBP/unc-18/SEC1 family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane

31033:ercc1
gene id: 31033:ercc1
uniprot id: H2U935
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERCC1/RAD10/SWI10 family.
messages: Nucleus

31033:LOC101068340
gene id: 31033:LOC101068340
uniprot id: H2SB17
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

31033:LOC101072117
gene id: 31033:LOC101072117
uniprot id: H2TW99
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

31033:snd1
gene id: 31033:snd1
uniprot id: Q6BCK4
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Endonuclease that mediates miRNA decay of both protein-free and AGO2-loaded miRNAs.

31033:prpf4b
gene id: 31033:prpf4b
uniprot id: H2T844
names: Function
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family.
messages: Has a role in pre-mRNA splicing. Phosphorylates SF2/ASF.

31033:LOC101077111
gene id: 31033:LOC101077111
uniprot id: A0A3B5KRU7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

31033:pcna
gene id: 31033:pcna
uniprot id: A0A3B5KHX6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PCNA family.
messages: Nucleus
messages: This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand.

31033:LOC101069053
gene id: 31033:LOC101069053
uniprot id: A0A674MN56
uniprot id: A0A674N8F2
names: Function
names: Subcellular Location Annotation
messages: Has E3 ubiquitin ligase activity towards IGBP1, promoting its monoubiquitination, which results in deprotection of the catalytic subunit of protein phosphatase PP2A, and its subsequent degradation by polyubiquitination.
messages: cytoskeleton

31033:slc9a3
gene id: 31033:slc9a3
uniprot id: H2U4K9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Membrane

31033:arfgef1
gene id: 31033:arfgef1
uniprot id: A0A674NYJ5
names: Subcellular Location Annotation
messages: Golgi apparatus
messages: perinuclear region

31033:LOC101070779
gene id: 31033:LOC101070779
uniprot id: H2UTK6
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Cell membrane
messages: Membrane
messages: Membrane raft
messages: caveola

31033:nectin1
gene id: 31033:nectin1
uniprot id: A0A674NCY8
names: Subcellular Location Annotation
messages: Membrane

31033:stra6
gene id: 31033:stra6
uniprot id: A0A3B5KUY8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

31033:gatc
gene id: 31033:gatc
uniprot id: A0A674PHV3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Mitochondrion
messages: Subunit of the heterotrimeric GatCAB amidotransferase (AdT) complex, composed of A (QRSL1), B (GATB) and C (GATC) subunits.

31033:ccdc58
gene id: 31033:ccdc58
uniprot id: H2V7P2
names: Similarity
messages: Belongs to the MIX23 family.

31033:max
gene id: 31033:max
uniprot id: H2V8X5
names: Similarity
messages: Belongs to the MAX family.

31033:rps6
gene id: 31033:rps6
uniprot id: A0A3B5KDW2
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS6 family.

31033:rps12
gene id: 31033:rps12
uniprot id: A0A674P0G1
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS12 family.

31033:LOC101076071
gene id: 31033:LOC101076071
uniprot id: A0A3B5KKL5
names: Subcellular Location Annotation
messages: Nucleus

31033:atp6v1f
gene id: 31033:atp6v1f
uniprot id: H2RMX7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase F subunit family.
messages: Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.

31033:dmrt3
gene id: 31033:dmrt3
uniprot id: Q90WM5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DMRT family.
messages: Nucleus
messages: Probable transcription factor that plays a role in configuring the spinal circuits controlling motion in vertebrates. Involved in neuronal specification within specific subdivision of spinal cord neurons and in the development of a coordinated locomotor network controlling movements. May regulate transcription (By similarity).

31033:plpbp
gene id: 31033:plpbp
uniprot id: H2S9R8
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which may be involved in intracellular homeostatic regulation of pyridoxal 5'-phosphate (PLP), the active form of vitamin B6.

31033:LOC101076758
gene id: 31033:LOC101076758
uniprot id: H2T767
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Heterodimer; with an rxr molecule. Binds DNA preferentially as a rar/rxr heterodimer.
messages: Nucleus

31033:bysl
gene id: 31033:bysl
uniprot id: H2TCZ2
names: Similarity
messages: Belongs to the bystin family.

31033:gins4
gene id: 31033:gins4
uniprot id: H2S4A2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GINS4/SLD5 family.
messages: Chromosome
messages: Nucleus
messages: Required for initiation of chromosomal DNA replication. Core component of CDC45-MCM-GINS (CMG) helicase, the molecular machine that unwinds template DNA during replication, and around which the replisome is built.

31033:ak6
gene id: 31033:ak6
uniprot id: H2S4U4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family. AK6 subfamily.
messages: Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. May have a role in nuclear energy homeostasis. Has also ATPase activity. May be involved in regulation of Cajal body (CB) formation.
messages: Cajal body
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer and homodimer. Interacts with COIL (via C-terminus).
messages: nucleoplasm

31033:LOC101067940
gene id: 31033:LOC101067940
uniprot id: H2RSH7
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

31033:ctnnb1
gene id: 31033:ctnnb1
uniprot id: H2S791
names: Similarity
messages: Belongs to the beta-catenin family.

31033:ate1
gene id: 31033:ate1
uniprot id: A0A674MAI8
uniprot id: A0A674MHQ2
names: Function
names: Similarity
messages: Belongs to the R-transferase family.
messages: Involved in the post-translational conjugation of arginine to the N-terminal aspartate or glutamate of a protein. This arginylation is required for degradation of the protein via the ubiquitin pathway.

31033:c6h9orf16
gene id: 31033:c6h9orf16
uniprot id: O73881
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0184 (EST00098) family.
messages: Cell junction
messages: Essential for intermediate filament organization in intestinal cells, interacts with intermediate filament and regulates intestinal lumen morphology.
messages: cytoskeleton

31033:atpsckmt
gene id: 31033:atpsckmt
uniprot id: H2SWH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ANT/ATPSC lysine N-methyltransferase family.
messages: Mitochondrion membrane

31033:LOC101062553
gene id: 31033:LOC101062553
uniprot id: H2S916
names: Similarity
messages: Belongs to the DNA photolyase class-1 family.

31033:LOC101071300
gene id: 31033:LOC101071300
uniprot id: H2UIG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes medium subunit family.
messages: Cytoplasmic vesicle membrane
messages: Golgi apparatus

31033:ppa2
gene id: 31033:ppa2
uniprot id: A0A674NT77
names: Similarity
messages: Belongs to the PPase family.

31033:ccnj
gene id: 31033:ccnj
uniprot id: H2TUP2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cyclin family. Cyclin AB subfamily.
messages: Essential for the control of the cell cycle at the G2/M (mitosis) transition.
messages: Interacts with the CDK1 protein kinase to form a serine/threonine kinase holoenzyme complex also known as maturation promoting factor (MPF). The cyclin subunit imparts substrate specificity to the complex.

31033:eaf1
gene id: 31033:eaf1
uniprot id: A0A674N9T7
names: Similarity
messages: Belongs to the EAF family.

31033:vti1a
gene id: 31033:vti1a
uniprot id: A0A3B5KM05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VTI1 family.
messages: Membrane

31033:arl1
gene id: 31033:arl1
uniprot id: A0A3B5KDV4
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.

31033:mcoln2
gene id: 31033:mcoln2
uniprot id: H2V6X8
names: Subcellular Location Annotation
messages: Endosome membrane
messages: Membrane

31033:LOC101069090
gene id: 31033:LOC101069090
uniprot id: A0A674NUN5
names: Subcellular Location Annotation
messages: Membrane

31033:LOC101065621
gene id: 31033:LOC101065621
uniprot id: A0A3B5K6I3
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Associates with the cytoplasmic CCR4-NOT deadenylase complex to trigger ARE-containing mRNA deadenylation and decay processes.
messages: Cytoplasm
messages: Nucleus
messages: Zinc-finger RNA-binding protein that destabilizes several cytoplasmic AU-rich element (ARE)-containing mRNA transcripts by promoting their poly(A) tail removal or deadenylation, and hence provide a mechanism for attenuating protein synthesis. Acts as a 3'-untranslated region (UTR) ARE mRNA-binding adapter protein to communicate signaling events to the mRNA decay machinery. Functions by recruiting the CCR4-NOT deadenylase complex and probably other components of the cytoplasmic RNA decay machinery to the bound ARE-containing mRNAs, and hence promotes ARE-mediated mRNA deadenylation and decay processes. Binds to 3'-UTR ARE of numerous mRNAs.

31033:bap1
gene id: 31033:bap1
uniprot id: H2UEV3
names: Similarity
messages: Belongs to the peptidase C12 family.

31033:LOC101076863
gene id: 31033:LOC101076863
uniprot id: H2T4Z8
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

31033:slc15a4
gene id: 31033:slc15a4
uniprot id: H2TPL0
uniprot id: H2TPL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane

31033:LOC101064878
gene id: 31033:LOC101064878
uniprot id: A0A3B5JX71
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

31033:LOC101071814
gene id: 31033:LOC101071814
uniprot id: H2TNR6
names: Similarity
messages: Belongs to the taxilin family.

31033:slu7
gene id: 31033:slu7
uniprot id: A0A674PCT8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associated with the spliceosome.
messages: Belongs to the SLU7 family.
messages: Involved in pre-mRNA splicing.
messages: Nucleus

31033:cldn11b
gene id: 31033:cldn11b
uniprot id: Q6E5T2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

31033:ska1
gene id: 31033:ska1
uniprot id: H2V5G4
names: Similarity
messages: Belongs to the SKA1 family.

31033:LOC101070409
gene id: 31033:LOC101070409
uniprot id: H2RUY8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H4 family.
messages: Chromosome
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

31033:pfdn5
gene id: 31033:pfdn5
uniprot id: H2SYT7
names: Similarity
messages: Belongs to the prefoldin subunit alpha family.

31033:rpl6
gene id: 31033:rpl6
uniprot id: H2UYH6
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL6 family.

31033:cog6
gene id: 31033:cog6
uniprot id: A0A674MMH9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COG6 family.
messages: Component of the conserved oligomeric Golgi complex which is composed of eight different subunits and is required for normal Golgi morphology and localization.
messages: Golgi apparatus membrane
messages: Membrane
messages: Required for normal Golgi function.

31033:cmtr1
gene id: 31033:cmtr1
uniprot id: H2ULE6
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: S-adenosyl-L-methionine-dependent methyltransferase that mediates RNA cap1 2'-O-ribose methylation to the 5'-cap structure of RNAs. Methylates the ribose of the first nucleotide of a m(7)GpppG-capped mRNA to produce m(7)GpppNmp (cap1).
messages: S-adenosyl-L-methionine-dependent methyltransferase that mediates mRNA cap1 2'-O-ribose methylation to the 5'-cap structure of mRNAs. Methylates the ribose of the first nucleotide of a m(7)GpppG-capped mRNA and small nuclear RNA (snRNA) to produce m(7)GpppRm (cap1). Displays a preference for cap0 transcripts. Cap1 modification is linked to higher levels of translation. May be involved in the interferon response pathway.

31033:LOC101061314
gene id: 31033:LOC101061314
uniprot id: A0A674NLC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Cationic amino acid transporter (CAT) (TC 2.A.3.3) family.
messages: Cell membrane
messages: Membrane

31033:pdxp
gene id: 31033:pdxp
uniprot id: H2V0P2
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

31033:LOC101079077
gene id: 31033:LOC101079077
uniprot id: A0A674NDN3
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.

31033:LOC101064278
gene id: 31033:LOC101064278
uniprot id: A0A674MVT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELO family.
messages: Membrane

31033:LOC101063305
gene id: 31033:LOC101063305
uniprot id: P61207
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: GTP-binding protein involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus.
messages: Golgi apparatus

31033:LOC101074575
gene id: 31033:LOC101074575
uniprot id: A0A674NQ88
names: Similarity
messages: Belongs to the WD repeat G protein beta family.

31033:npffr-2
gene id: 31033:npffr-2
uniprot id: Q05KN2
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: Receptor for NPAF (A-18-F-amide) and NPFF (F-8-F-amide) neuropeptides, also known as morphine-modulating peptides. Can also be activated by a variety of naturally occurring or synthetic FMRF-amide like ligands. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.

31033:LOC101074448
gene id: 31033:LOC101074448
uniprot id: H2RVW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

31033:tbca
gene id: 31033:tbca
uniprot id: H2VCA5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TBCA family.
messages: Supercomplex made of cofactors A to E. Cofactors A and D function by capturing and stabilizing tubulin in a quasi-native conformation. Cofactor E binds to the cofactor D-tubulin complex; interaction with cofactor C then causes the release of tubulin polypeptides that are committed to the native state.
messages: Tubulin-folding protein; involved in the early step of the tubulin folding pathway.
messages: cytoskeleton

31033:LOC101064914
gene id: 31033:LOC101064914
uniprot id: Q7SZG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR2 subfamily.
messages: Nucleus

31033:tsen15
gene id: 31033:tsen15
uniprot id: A0A3B5KG50
names: Similarity
messages: Belongs to the SEN15 family.

31033:zc3h12b
gene id: 31033:zc3h12b
uniprot id: H2U1P2
names: Similarity
messages: Belongs to the ZC3H12 family.

31033:LOC101077246
gene id: 31033:LOC101077246
uniprot id: H2RR32
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

31033:LOC101074624
gene id: 31033:LOC101074624
uniprot id: H2SWM4
names: Similarity
messages: Belongs to the EPS8 family.

31033:shoc2
gene id: 31033:shoc2
uniprot id: A0A3B5JX95
names: Function
names: Similarity
messages: Belongs to the SHOC2 family.
messages: Regulatory subunit of protein phosphatase 1 (PP1c) that acts as a M-Ras/MRAS effector and participates in MAPK pathway activation. Upon M-Ras/MRAS activation, targets PP1c to specifically dephosphorylate the 'Ser-259' inhibitory site of RAF1 kinase and stimulate RAF1 activity at specialized signaling complexes.

31033:LOC101066528
gene id: 31033:LOC101066528
uniprot id: H2RKG9
names: Similarity
messages: Belongs to the Niban family.

31033:hoxc13
gene id: 31033:hoxc13
uniprot id: Q1KKV4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

31033:wdfy2
gene id: 31033:wdfy2
uniprot id: A0A674MKJ0
names: Subcellular Location Annotation
messages: Early endosome
messages: Endosome

31033:slc35a4
gene id: 31033:slc35a4
uniprot id: H2SPA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide-sugar transporter family. SLC35A subfamily.
messages: Membrane

31033:LOC101067856
gene id: 31033:LOC101067856
uniprot id: A0A3B5KGR1
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cAMP subfamily.

31033:LOC101070008
gene id: 31033:LOC101070008
uniprot id: H2U5S9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
messages: Membrane

31033:six3
gene id: 31033:six3
uniprot id: H2T103
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SIX/Sine oculis homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

31033:sox21
gene id: 31033:sox21
uniprot id: A0A3B5KJ66
names: Subcellular Location Annotation
messages: Nucleus

31033:yipf5
gene id: 31033:yipf5
uniprot id: H2SS94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YIP1 family.
messages: Membrane

31033:LOC101072238
gene id: 31033:LOC101072238
uniprot id: A0A3B5KJ68
uniprot id: A0A3B5KQ21
names: Similarity
messages: Belongs to the ribose-phosphate pyrophosphokinase family.

31033:LOC101065136
gene id: 31033:LOC101065136
uniprot id: A0A674NQN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIC subfamily.
messages: Cell membrane

31033:LOC101065699
gene id: 31033:LOC101065699
uniprot id: A0A3B5KQ92
names: Subcellular Location Annotation
messages: Nucleus

31033:LOC101068020
gene id: 31033:LOC101068020
uniprot id: A0A3B5K2X8
names: Similarity
messages: Belongs to the tumor necrosis factor family.

31033:LOC101078242
gene id: 31033:LOC101078242
uniprot id: H2TH23
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat coronin family.
messages: Regulates leading edge dynamics and cell motility in fibroblasts. May be involved in cytokinesis and signal transduction.
messages: stress fiber

31033:LOC101078278
gene id: 31033:LOC101078278
uniprot id: H2TEB6
names: Subcellular Location Annotation
messages: Membrane

31033:LOC101078094
gene id: 31033:LOC101078094
uniprot id: Q9W6R0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes small subunit family.
messages: Cytoplasmic vesicle membrane
messages: Golgi apparatus
messages: clathrin-coated pit

31033:sdad1
gene id: 31033:sdad1
uniprot id: H2UBV3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SDA1 family.
messages: Required for 60S pre-ribosomal subunits export to the cytoplasm.
messages: nucleolus

31033:hdhd3
gene id: 31033:hdhd3
uniprot id: A0A674PER4
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

31033:psmb8
gene id: 31033:psmb8
uniprot id: A0A674MQY3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome complex.
messages: Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
messages: Cytoplasm
messages: Nucleus
messages: The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. This subunit is involved in antigen processing to generate class I binding peptides.

31033:amacr
gene id: 31033:amacr
uniprot id: H2UIN6
names: Similarity
messages: Belongs to the CoA-transferase III family.

31033:slc35b4
gene id: 31033:slc35b4
uniprot id: A0A3B5K1Q1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide-sugar transporter family. SLC35B subfamily.
messages: Membrane

31033:vkorc1l1
gene id: 31033:vkorc1l1
uniprot id: Q6TEK8
names: Activity Regulation
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VKOR family.
messages: Endoplasmic reticulum membrane
messages: Inhibited by warfarin (coumadin) (PubMed:33154105). Warfarin locks VKORC1 in both redox states into the closed conformation (PubMed:33154105).
messages: Involved in vitamin K metabolism (PubMed:33154105). Can reduce inactive vitamin K 2,3-epoxide to active vitamin K, and may contribute to vitamin K-mediated protection against oxidative stress (PubMed:33154105). Plays a role in vitamin K-dependent gamma-carboxylation of Glu residues in target proteins (By similarity).
messages: Partially oxidized VKORC1 forms a cysteine adduct with substrates, vitamin K 2,3-epoxide, inducing a closed conformation, juxtaposing all cysteines (S-S or SH) for unimpeded electron transfer (PubMed:33154105). VKOR becomes fully oxidized with an open conformation that releases reaction products, vitamin K quinone, or hydroquinone (PubMed:33154105). Cys-138 and Cys-141 constitute the catalytic redox-active center (PubMed:33154105). Cys-49 and Cys-57 are the cysteine pair that mediates transfer of reducing equivalents during catalysis (PubMed:33154105).

31033:ndufa13
gene id: 31033:ndufa13
uniprot id: A0A674MA45
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I NDUFA13 subunit family.
messages: Complex I functions in the transfer of electrons from NADH to the respiratory chain. Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis.
messages: Mitochondrion inner membrane

31033:slc2a9
gene id: 31033:slc2a9
uniprot id: A0A674N1C7
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

31033:LOC101063412
gene id: 31033:LOC101063412
uniprot id: H2UGG7
names: Function
names: Similarity
messages: Belongs to the PET191 family.
messages: Involved in an early step of the mitochondrial complex IV assembly process.

31033:LOC101061562
gene id: 31033:LOC101061562
uniprot id: H2TVI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
messages: Nucleus

31033:prdm1
gene id: 31033:prdm1
uniprot id: Q75UA3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class V-like SAM-binding methyltransferase superfamily.
messages: Cytoplasm
messages: Interacts with PRMT5. Interacts with FBXO10. Interacts with FBXO11.
messages: Nucleus
messages: Transcription factor that mediates a transcriptional program in various innate and adaptive immune tissue-resident lymphocyte T cell types such as tissue-resident memory T (Trm), natural killer (trNK) and natural killer T (NKT) cells and negatively regulates gene expression of proteins that promote the egress of tissue-resident T-cell populations from non-lymphoid organs. Plays a role in the development, retention and long-term establishment of adaptive and innate tissue-resident lymphocyte T cell types in non-lymphoid organs, such as the skin and gut, but also in other nonbarrier tissues like liver and kidney, and therefore may provide immediate immunological protection against reactivating infections or viral reinfection. Binds specifically to the PRDI element in the promoter of the beta-interferon gene. Drives the maturation of B-lymphocytes into Ig secreting cells. Associates with the transcriptional repressor ZNF683 to chromatin at gene promoter regions.

31033:nkiras1
gene id: 31033:nkiras1
uniprot id: H2TCT2
names: Similarity
messages: Belongs to the small GTPase superfamily. Ras family. KappaB-Ras subfamily.

31033:LOC101062878
gene id: 31033:LOC101062878
uniprot id: H2SIP9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

31033:LOC101079670
gene id: 31033:LOC101079670
uniprot id: A0A674P369
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family. UEV subfamily.

31033:sfmbt1
gene id: 31033:sfmbt1
uniprot id: H2SDN0
names: Subcellular Location Annotation
messages: Nucleus

31033:LOC101067257
gene id: 31033:LOC101067257
uniprot id: H2TJG5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTR/RAG GTP-binding protein family.
messages: Cytoplasm
messages: Guanine nucleotide-binding protein that plays a crucial role in the cellular response to amino acid availability through regulation of the mTORC1 signaling cascade.
messages: Lysosome

31033:gbx1
gene id: 31033:gbx1
uniprot id: H2SL54
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

31033:LOC101074720
gene id: 31033:LOC101074720
uniprot id: H2UH33
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFB2 family.
messages: Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA.
messages: Nucleus

31033:psmd13
gene id: 31033:psmd13
uniprot id: A0A674PII0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the proteasome subunit S11 family.
messages: Component of the 19S proteasome regulatory particle complex. The 26S proteasome consists of a 20S core particle (CP) and two 19S regulatory subunits (RP). The regulatory particle is made of a lid composed of 9 subunits including PSMD13, a base containing 6 ATPases and few additional components.
messages: Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair.

31033:mrps30
gene id: 31033:mrps30
uniprot id: A0A3B5K3G9
names: Subcellular Location Annotation
messages: Mitochondrion

31033:LOC101066482
gene id: 31033:LOC101066482
uniprot id: A0A674P431
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Rab GDI family.
messages: Cytoplasm
messages: Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP.

31033:slc66a2
gene id: 31033:slc66a2
uniprot id: A0A3B5K718
uniprot id: H2U6N7
names: Subcellular Location Annotation
messages: Membrane

31033:nkx3-2
gene id: 31033:nkx3-2
uniprot id: H2UJ02
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

31033:psmg2
gene id: 31033:psmg2
uniprot id: H2SS41
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PSMG2 family.
messages: Chaperone protein which promotes assembly of the 20S proteasome as part of a heterodimer with PSMG1.
messages: Forms a heterodimer with PSMG1.

31033:ube2s
gene id: 31033:ube2s
uniprot id: H2S8M4
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

31033:LOC101079669
gene id: 31033:LOC101079669
uniprot id: H2URQ3
names: Similarity
messages: Belongs to the ATP:guanido phosphotransferase family.

31033:LOC101068771
gene id: 31033:LOC101068771
uniprot id: H2SSW6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

31033:ntsr1
gene id: 31033:ntsr1
uniprot id: H2T747
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

31033:LOC101070900
gene id: 31033:LOC101070900
uniprot id: A0A674P7I6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

31033:LOC101067277
gene id: 31033:LOC101067277
uniprot id: H2RJL2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP Sm proteins family.
messages: Nucleus
messages: Plays a role in pre-mRNA splicing as a core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome.

31033:LOC101071937
gene id: 31033:LOC101071937
uniprot id: H2V462
names: Similarity
messages: Belongs to the peptidase C19 family.

31033:prkd2
gene id: 31033:prkd2
uniprot id: H2U720
names: Activity Regulation
names: Similarity
names: Subcellular Location Annotation
messages: Activated by DAG and phorbol esters.
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PKD subfamily.
messages: Cytoplasm
messages: Membrane

31033:eogt
gene id: 31033:eogt
uniprot id: Q5NDK8
names: Similarity
messages: Belongs to the glycosyltransferase 61 family.

31033:tmem9b
gene id: 31033:tmem9b
uniprot id: A0A3B5K4J5
names: Similarity
messages: Belongs to the TMEM9 family.

31033:tpx2
gene id: 31033:tpx2
uniprot id: H2TEZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TPX2 family.
messages: spindle

31033:arsb
gene id: 31033:arsb
uniprot id: H2S6H5
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

31033:LOC101069559
gene id: 31033:LOC101069559
uniprot id: H2SJ42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABI family.
messages: cytoskeleton
messages: filopodium
messages: lamellipodium

31033:ada2
gene id: 31033:ada2
uniprot id: H2RVT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. ADGF subfamily.
messages: Secreted

31033:LOC101078192
gene id: 31033:LOC101078192
uniprot id: H2S8M7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: cytosol

31033:naxd
gene id: 31033:naxd
uniprot id: H2TJQ1
names: Function
names: Similarity
messages: Belongs to the NnrD/CARKD family.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ATP, which is converted to ADP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.

31033:tmem205
gene id: 31033:tmem205
uniprot id: A0A3B5KSE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM205 family.
messages: Membrane

31033:kdm3b
gene id: 31033:kdm3b
uniprot id: H2RPL3
names: Subcellular Location Annotation
messages: Nucleus

31033:ccdc22
gene id: 31033:ccdc22
uniprot id: H2RV50
names: Similarity
messages: Belongs to the CCDC22 family.

31033:LOC101069539
gene id: 31033:LOC101069539
uniprot id: A0A3B5JXG0
names: Similarity
messages: Belongs to the requiem/DPF family.

31033:LOC101061764
gene id: 31033:LOC101061764
uniprot id: A0A674N9Y0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COA3 family.
messages: Component of 250-400 kDa complexes called cytochrome oxidase assembly intermediates or COA complexes.
messages: Core component of the MITRAC (mitochondrial translation regulation assembly intermediate of cytochrome c oxidase complex) complex, that regulates cytochrome c oxidase assembly. MITRAC complexes regulate both translation of mitochondrial encoded components and assembly of nuclear-encoded components imported in mitochondrion. Required for efficient translation of MT-CO1 and mitochondrial respiratory chain complex IV assembly.
messages: Membrane
messages: Required for assembly of cytochrome c oxidase (complex IV).

31033:etfdh
gene id: 31033:etfdh
uniprot id: H2UWL6
names: Cofactor
names: Function
messages: Accepts electrons from ETF and reduces ubiquinone.
messages: Binds 1 [4Fe-4S] cluster.

31033:LOC101076671
gene id: 31033:LOC101076671
uniprot id: H2UIJ1
names: Similarity
messages: Belongs to the SKI family.

31033:thbs1
gene id: 31033:thbs1
uniprot id: H2UJX9
names: Caution
names: Similarity
messages: Belongs to the thrombospondin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

31033:lingo1
gene id: 31033:lingo1
uniprot id: H2UW86
names: Subcellular Location Annotation
messages: Membrane

31033:nr2e1
gene id: 31033:nr2e1
uniprot id: Q8JHW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

31033:LOC101075600
gene id: 31033:LOC101075600
uniprot id: H2TAQ3
names: Similarity
messages: Belongs to the SNF7 family.

31033:LOC101065324
gene id: 31033:LOC101065324
uniprot id: A0A674MRY9
names: Similarity
messages: Belongs to the ATG8 family.

31033:LOC101071319
gene id: 31033:LOC101071319
uniprot id: A0A674NTW6
uniprot id: H2SMY8
names: Similarity
messages: Belongs to the band 7/mec-2 family.

31033:dck
gene id: 31033:dck
uniprot id: A0A674PNN2
names: Similarity
messages: Belongs to the DCK/DGK family.

31033:cldn30c
gene id: 31033:cldn30c
uniprot id: Q6E5R8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: tight junction

31033:c21h9orf78
gene id: 31033:c21h9orf78
uniprot id: A0A674MUH0
names: Similarity
messages: Belongs to the TLS1 family.

31033:kdsr
gene id: 31033:kdsr
uniprot id: A0A674P0N9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

31033:mmp13
gene id: 31033:mmp13
uniprot id: H2S9U1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M10A family.
messages: Secreted

31033:usp33
gene id: 31033:usp33
uniprot id: A0A674NUC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C19 family. USP20/USP33 subfamily.
messages: centrosome
messages: perinuclear region

31033:ssr2
gene id: 31033:ssr2
uniprot id: H2UIQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP-beta family.
messages: Endoplasmic reticulum membrane
messages: Heterotetramer of TRAP-alpha, TRAP-beta, TRAP-delta and TRAP-gamma.
messages: Membrane
messages: TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins.

31033:gsx1
gene id: 31033:gsx1
uniprot id: H2V244
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

31033:smc5
gene id: 31033:smc5
uniprot id: Q802R9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family. SMC5 subfamily.
messages: Chromosome
messages: Core component of the SMC5-SMC6 complex, a complex involved in repair of DNA double-strand breaks by homologous recombination. The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks. The complex is required for telomere maintenance via recombination and mediates sumoylation of shelterin complex (telosome) components. Required for sister chromatid cohesion during prometaphase and mitotic progression; the function seems to be independent of SMC6 (By similarity).
messages: Forms a heterodimer with smc6. Component of the SMC5-SMC6 complex which consists at least of smc5, smc6, nsmce2, nsmce1 and nsmce4a (By similarity).
messages: Nucleus
messages: The flexible hinge domain, which separates the large intramolecular coiled coil regions, allows the heterotypic interaction with the corresponding domain of SMC6, forming a V-shaped heterodimer.
messages: telomere

31033:urod
gene id: 31033:urod
uniprot id: H2S7Q7
names: Similarity
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Homodimer.

31033:tmem199
gene id: 31033:tmem199
uniprot id: A0A3B5KJI4
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

31033:LOC101066562
gene id: 31033:LOC101066562
uniprot id: A0A674MMQ5
names: Subcellular Location Annotation
messages: Nucleus

31033:sf3b1
gene id: 31033:sf3b1
uniprot id: H2URZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SF3B1 family.
messages: Nucleus

31033:arf1
gene id: 31033:arf1
uniprot id: A0A3B5KDL4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: GTP-binding protein involved in protein trafficking; modulates vesicle budding and uncoating within the Golgi apparatus.
messages: Golgi apparatus

31033:cd247
gene id: 31033:cd247
uniprot id: A0A3B5KEI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CD3Z/FCER1G family.
messages: Cell membrane
messages: Membrane

31033:LOC101061715
gene id: 31033:LOC101061715
uniprot id: H2VF25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: centrosome

31033:LOC101068011
gene id: 31033:LOC101068011
uniprot id: A0A3B5KA00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family.
messages: Membrane

31033:vax2
gene id: 31033:vax2
uniprot id: H2VAK3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMX homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

31033:cnmd
gene id: 31033:cnmd
uniprot id: H2TFL7
names: Similarity
messages: Belongs to the chondromodulin-1 family.

31033:LOC101076943
gene id: 31033:LOC101076943
uniprot id: A0A674NZ63
names: Similarity
messages: Belongs to the eukaryotic initiation factor 4E family.

31033:LOC101074923
gene id: 31033:LOC101074923
uniprot id: H2TGH0
names: Similarity
messages: Belongs to the peptidase C19 family.

31033:fgb
gene id: 31033:fgb
uniprot id: H2S183
names: Subcellular Location Annotation
names: Subunit
messages: Heterohexamer; disulfide linked. Contains 2 sets of 3 non-identical chains (alpha, beta and gamma). The 2 heterotrimers are in head to head conformation with the N-termini in a small central domain.
messages: Secreted

31033:LOC101078875
gene id: 31033:LOC101078875
uniprot id: H2SX46
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

31033:unc45b
gene id: 31033:unc45b
uniprot id: A0A674MWX1
names: Subcellular Location Annotation
messages: perinuclear region

31033:mfsd1
gene id: 31033:mfsd1
uniprot id: H2SAM5
uniprot id: H2SAM7
names: Subcellular Location Annotation
messages: Membrane

31033:LOC105416362
gene id: 31033:LOC105416362
uniprot id: A0A3B5KNK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Vesicular transporter family.
messages: Membrane

31033:LOC101061612
gene id: 31033:LOC101061612
uniprot id: H2RIS3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
messages: Membrane
messages: Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state.

31033:LOC101065757
gene id: 31033:LOC101065757
uniprot id: H2UJA5
names: Subcellular Location Annotation
messages: Membrane

31033:st6galnac5
gene id: 31033:st6galnac5
uniprot id: Q6ZXY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

31033:LOC101076273
gene id: 31033:LOC101076273
uniprot id: H2TKH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NALF family.
messages: Membrane

31033:inpp5a
gene id: 31033:inpp5a
uniprot id: H2THM1
names: Similarity
messages: Belongs to the inositol 1,4,5-trisphosphate 5-phosphatase type I family.

31033:rexo2
gene id: 31033:rexo2
uniprot id: A0A3B5K3L7
names: Similarity
messages: Belongs to the oligoribonuclease family.

31033:cep55
gene id: 31033:cep55
uniprot id: H2TSC5
names: Subcellular Location Annotation
messages: Cytoplasm

31033:thoc2
gene id: 31033:thoc2
uniprot id: H2UNV2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the THOC2 family.
messages: Component of the THO complex, which is composed of THOC1, THOC2, THOC3, THOC5, THOC6 and THOC7; together with at least ALYREF/THOC4, DDX39B, SARNP/CIP29 and CHTOP, THO forms the transcription/export (TREX) complex which seems to have a dynamic structure involving ATP-dependent remodeling. Interacts with THOC1, POLDIP3 and ZC3H11A.
messages: Nucleus

31033:mbnl3
gene id: 31033:mbnl3
uniprot id: Q56V19
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Tissue Specificity
messages: Belongs to the muscleblind family.
messages: Cytoplasm
messages: Expressed in fast and slow myotomal muscle, heart, liver, skin, brain and testis.
messages: Involved in pre-mRNA alternative splicing regulation. Could inhibit terminal muscle differentiation, acting at approximately the time of myogenin induction (By similarity).
messages: Nucleus

31033:uchl1
gene id: 31033:uchl1
uniprot id: H2UQN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C12 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

31033:kat8
gene id: 31033:kat8
uniprot id: A0A3B5K9B9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MYST (SAS/MOZ) family.
messages: Nucleus

31033:mcm5
gene id: 31033:mcm5
uniprot id: A0A3B5KD99
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.
messages: Belongs to the MCM family.
messages: Component of the MCM2-7 complex.
messages: Nucleus

31033:LOC101073769
gene id: 31033:LOC101073769
uniprot id: H2TA05
uniprot id: H2TA06
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

31033:nek3
gene id: 31033:nek3
uniprot id: H2UHD1
names: Similarity
messages: Belongs to the protein kinase superfamily.

31033:snrpa
gene id: 31033:snrpa
uniprot id: H2TI81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM U1 A/B'' family.
messages: Nucleus

31033:slc35a1
gene id: 31033:slc35a1
uniprot id: Q50J29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide-sugar transporter family. SLC35A subfamily.
messages: Membrane

31033:LOC101077048
gene id: 31033:LOC101077048
uniprot id: A0A3B5KB16
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SCC3 family.
messages: Chromosome
messages: Component of cohesin complex, a complex required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate.
messages: Nucleus
messages: Part of the cohesin complex which is composed of a heterodimer between a SMC1 protein (SMC1A or SMC1B) and SMC3, which are attached via their hinge domain, and RAD21 which link them at their heads, and one STAG protein.
messages: centromere

31033:LOC101075610
gene id: 31033:LOC101075610
uniprot id: H2U9I0
names: Subcellular Location Annotation
messages: Membrane

31033:tcf7l2
gene id: 31033:tcf7l2
uniprot id: H2U4B6
uniprot id: H2U4B7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCF/LEF family.
messages: Nucleus

31033:psma5
gene id: 31033:psma5
uniprot id: A0A674NQV3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.

31033:slc35c2
gene id: 31033:slc35c2
uniprot id: A0A674NLU0
uniprot id: A0A674PDD1
names: Subcellular Location Annotation
messages: Membrane

31033:LOC105416219
gene id: 31033:LOC105416219
uniprot id: H2SF09
names: Subcellular Location Annotation
messages: Membrane

31033:taf11
gene id: 31033:taf11
uniprot id: A0A3B5JZU1
names: Similarity
messages: Belongs to the TAF11 family.

31033:LOC101068225
gene id: 31033:LOC101068225
uniprot id: H2UHB6
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

31033:lcat
gene id: 31033:lcat
uniprot id: A0A674PAM7
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

31033:LOC101065890
gene id: 31033:LOC101065890
uniprot id: A0A674P9W4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

31033:llph
gene id: 31033:llph
uniprot id: H2UR87
names: Similarity
messages: Belongs to the learning-associated protein family.

31033:lyar
gene id: 31033:lyar
uniprot id: H2UHR1
names: Subcellular Location Annotation
messages: Cytoplasm

31033:LOC101075813
gene id: 31033:LOC101075813
uniprot id: A0A3B5KIU0
names: Similarity
messages: Belongs to the heat shock protein 70 family.

31033:lnpk
gene id: 31033:lnpk
uniprot id: H2V6X4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the lunapark family.
messages: Endoplasmic reticulum membrane
messages: Homodimer; homodimerization requires the C4-type zinc finger motif and decreases during mitosis in a phosphorylation-dependent manner.
messages: Plays a role in determining ER morphology.
messages: The C4-type zinc finger motif is necessary both for its ER three-way tubular junction localization and formation.

31033:LOC101072922
gene id: 31033:LOC101072922
uniprot id: H2SJJ3
names: Subcellular Location Annotation
messages: Nucleus

31033:nup88
gene id: 31033:nup88
uniprot id: A0A3B5KMA8
names: Subcellular Location Annotation
messages: nuclear pore complex

31033:tmem151b
gene id: 31033:tmem151b
uniprot id: A0A3B5KCG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM151 family.
messages: Membrane

31033:LOC101069201
gene id: 31033:LOC101069201
uniprot id: A0A674MQ65
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

31033:LOC101063931
gene id: 31033:LOC101063931
uniprot id: A0A674MU78
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAIF1 family.
messages: Induces apoptosis.
messages: Nucleus

31033:LOC101062110
gene id: 31033:LOC101062110
uniprot id: H2V282
names: Similarity
messages: Belongs to the calycin superfamily. Lipocalin family.

31033:LOC101070461
gene id: 31033:LOC101070461
uniprot id: H2UQR1
names: Similarity
messages: Belongs to the importin alpha family.

31033:LOC101062644
gene id: 31033:LOC101062644
uniprot id: A0A3B5KER9
names: Similarity
messages: Belongs to the FAM219 family.

31033:naa10
gene id: 31033:naa10
uniprot id: A0A674MW43
names: Similarity
messages: Belongs to the acetyltransferase family. ARD1 subfamily.

31033:LOC101072650
gene id: 31033:LOC101072650
uniprot id: H2SSP7
names: Similarity
messages: Belongs to the PPP phosphatase family. PP-2B subfamily.

31033:LOC101077547
gene id: 31033:LOC101077547
uniprot id: H2TUH4
names: Subcellular Location Annotation
messages: Membrane

31033:paf1
gene id: 31033:paf1
uniprot id: H2SNJ1
names: Similarity
messages: Belongs to the PAF1 family.

31033:LOC101073067
gene id: 31033:LOC101073067
uniprot id: H2TZR7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/PBX homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

31033:ing4
gene id: 31033:ing4
uniprot id: H2S021
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ING family.
messages: Component of an histone acetyltransferase complex.
messages: Component of an histone acetyltransferase complex. Interacts with H3K4me3 and to a lesser extent with H3K4me2.
messages: Nucleus
messages: The PHD-type zinc finger mediates the binding to H3K4me3.

31033:tent5b
gene id: 31033:tent5b
uniprot id: A0A3B5KEU6
names: Similarity
messages: Belongs to the TENT family.

31033:LOC101064440
gene id: 31033:LOC101064440
uniprot id: H2RJV7
names: Similarity
messages: Belongs to the lipin family.

31033:LOC101067323
gene id: 31033:LOC101067323
uniprot id: H2UK75
names: Similarity
messages: Belongs to the RAMP family.

31033:gje1
gene id: 31033:gje1
uniprot id: A0A674MMZ8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

31033:hint3
gene id: 31033:hint3
uniprot id: A0A674P9P5
names: Similarity
messages: Belongs to the HINT family.

31033:LOC101076009
gene id: 31033:LOC101076009
uniprot id: A0A674MA50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNAJC25 family.
messages: Membrane

31033:pxmp2
gene id: 31033:pxmp2
uniprot id: A0A674N0J0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxisomal membrane protein PXMP2/4 family.
messages: Membrane

31033:LOC101074997
gene id: 31033:LOC101074997
uniprot id: H2SLA2
names: Function
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PIM subfamily.
messages: Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation.

31033:cav3
gene id: 31033:cav3
uniprot id: A0A674NPA8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the caveolin family.
messages: Cell membrane
messages: Golgi apparatus membrane
messages: May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity.
messages: Membrane
messages: caveola
messages: sarcolemma

31033:dmrt1
gene id: 31033:dmrt1
uniprot id: H2UT51
uniprot id: Q4AE32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DMRT family.
messages: Nucleus

31033:gtf2e1
gene id: 31033:gtf2e1
uniprot id: H2T3F1
names: Function
names: Similarity
messages: Belongs to the TFIIE alpha subunit family.
messages: Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.

31033:dynlt3
gene id: 31033:dynlt3
uniprot id: A0A674MJ23
names: Similarity
messages: Belongs to the dynein light chain Tctex-type family.

31033:gcnt4
gene id: 31033:gcnt4
uniprot id: H2UAR1
names: Subcellular Location Annotation
messages: Golgi apparatus membrane
messages: Membrane

31033:LOC101077756
gene id: 31033:LOC101077756
uniprot id: Q9DES1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome complex.
messages: Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
messages: Cytoplasm
messages: Nucleus
messages: The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. This subunit is involved in antigen processing to generate class I binding peptides.

31033:LOC101077836
gene id: 31033:LOC101077836
uniprot id: A0A3B5KQE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFIIF beta subunit family.
messages: Nucleus

31033:LOC101069303
gene id: 31033:LOC101069303
uniprot id: A0A674M9Q7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAPT1 family.
messages: Membrane

31033:LOC101064537
gene id: 31033:LOC101064537
uniprot id: H2VCU0
uniprot id: Q6ZXZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

31033:LOC101068129
gene id: 31033:LOC101068129
uniprot id: Q6W953
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family. Bicoid subfamily.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

31033:LOC101065997
gene id: 31033:LOC101065997
uniprot id: A0A3B5K5Y3
names: Similarity
messages: Belongs to the inositol phosphokinase (IPK) family.

31033:LOC101072042
gene id: 31033:LOC101072042
uniprot id: H2TQR7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone deacetylase family. HD Type 1 subfamily.
messages: Histone deacetylase that catalyzes the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Also functions as deacetylase for non-histone proteins.
messages: Nucleus

31033:satb2
gene id: 31033:satb2
uniprot id: H2UQV0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CUT homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

31033:nipsnap2
gene id: 31033:nipsnap2
uniprot id: A0A674PG77
names: Similarity
messages: Belongs to the NipSnap family.

31033:LOC101062215
gene id: 31033:LOC101062215
uniprot id: H2SNG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M14 family.
messages: Secreted

31033:hat1
gene id: 31033:hat1
uniprot id: H2V8E9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAT1 family.
messages: Catalytic subunit of the type B histone acetyltransferase (HAT) complex, composed of RBBP7 and HAT1. Interacts with histones H4 and H2A.
messages: Histone acetyltransferase that plays a role in different biological processes including cell cycle progression, glucose metabolism, histone production or DNA damage repair. Coordinates histone production and acetylation via H4 promoter binding. Acetylates histone H4 at 'Lys-5' (H4K5ac) and 'Lys-12' (H4K12ac) and, to a lesser extent, histone H2A at 'Lys-5' (H2AK5ac).

31033:charon
gene id: 31033:charon
uniprot id: Q76C28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DAN family.
messages: Secreted

31033:LOC101065875
gene id: 31033:LOC101065875
uniprot id: A0A674PLM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane

31033:LOC101071127
gene id: 31033:LOC101071127
uniprot id: H2SWC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RIX1/PELP1 family.
messages: Cytoplasm
messages: Nucleus

31033:c21h2orf68
gene id: 31033:c21h2orf68
uniprot id: H2TV01
names: Similarity
messages: Belongs to the UPF0561 family.

31033:LOC101071662
gene id: 31033:LOC101071662
uniprot id: H2S672
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. WEE1 subfamily.
messages: Binds 2 magnesium ions per subunit.
messages: Nucleus

31033:LOC101075102
gene id: 31033:LOC101075102
uniprot id: H2RRQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELO family.
messages: Membrane

31033:LOC101072863
gene id: 31033:LOC101072863
uniprot id: H2TXB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-alpha family. G(12) subfamily.
messages: Membrane

31033:LOC101064366
gene id: 31033:LOC101064366
uniprot id: A0A674NXM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAPP small subunits family. BET3 subfamily.
messages: Endoplasmic reticulum
messages: cis-Golgi network

31033:ro60
gene id: 31033:ro60
uniprot id: H2THV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ro 60 kDa family.
messages: Cytoplasm

31033:cyp17a2
gene id: 31033:cyp17a2
uniprot id: A7U485
names: Similarity
messages: Belongs to the cytochrome P450 family.

31033:srf
gene id: 31033:srf
uniprot id: H2V6U8
names: Subcellular Location Annotation
messages: Nucleus

31033:fgf22
gene id: 31033:fgf22
uniprot id: A0A3B5K7I9
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

31033:tbx1
gene id: 31033:tbx1
uniprot id: H2UFY5
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

31033:tgf-beta1
gene id: 31033:tgf-beta1
uniprot id: H2UV73
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TGF-beta family.
messages: Homodimer; disulfide-linked.
messages: Transforming growth factor beta-1 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-1 (TGF-beta-1) chains, which constitute the regulatory and active subunit of TGF-beta-1, respectively.
messages: extracellular matrix

31033:LOC101062822
gene id: 31033:LOC101062822
uniprot id: A0A674MZ83
names: Function
names: Similarity
messages: Belongs to the troponin T family.
messages: Troponin T is the tropomyosin-binding subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.

31033:igflr1
gene id: 31033:igflr1
uniprot id: A0A674N640
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

31033:fibin
gene id: 31033:fibin
uniprot id: H2UY08
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FIBIN family.
messages: Endoplasmic reticulum
messages: Golgi apparatus
messages: Homodimer; disulfide-linked. Seems to also exist as monomers.
messages: Secreted

31033:LOC101067003
gene id: 31033:LOC101067003
uniprot id: A0A3B5JZ25
names: Similarity
messages: Belongs to the GADD45 family.

31033:capza2
gene id: 31033:capza2
uniprot id: A0A674P3V0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the F-actin-capping protein alpha subunit family.
messages: F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
messages: Heterodimer of an alpha and a beta subunit.

31033:LOC101067179
gene id: 31033:LOC101067179
uniprot id: A0A674P9F3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.
messages: cytoskeleton

31033:LOC101062232
gene id: 31033:LOC101062232
uniprot id: A0A674NZY7
names: Similarity
messages: Belongs to the BRAG family.

31033:wap65-2
gene id: 31033:wap65-2
uniprot id: Q75UL8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the hemopexin family.
messages: Binds heme and transports it to the liver for breakdown and iron recovery, after which the free hemopexin returns to the circulation.
messages: Secreted

31033:atp5mg
gene id: 31033:atp5mg
uniprot id: A0A674MIK6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase g subunit family.
messages: Membrane
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. Minor subunit located with subunit a in the membrane.
messages: Mitochondrial membrane ATP synthase (F1F0 ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F1 - containing the extramembraneous catalytic core, and F0 - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F1 is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F0 domain. Minor subunit located with subunit a in the membrane.
messages: Mitochondrion

31033:LOC101069214
gene id: 31033:LOC101069214
uniprot id: A0A674MGJ0
names: Similarity
messages: Belongs to the beta-catenin family.

31033:LOC445941
gene id: 31033:LOC445941
uniprot id: Q804X0
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular space

31033:timp4
gene id: 31033:timp4
uniprot id: Q7ZTB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protease inhibitor I35 (TIMP) family.
messages: Secreted

31033:manf
gene id: 31033:manf
uniprot id: A0A674ND02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ARMET family.
messages: Secreted

31033:pdcl
gene id: 31033:pdcl
uniprot id: A0A3B5KIS2
names: Similarity
messages: Belongs to the phosducin family.

31033:ak3
gene id: 31033:ak3
uniprot id: H2TQ17
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family. AK3 subfamily.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon GTP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent GTP hydrolysis.
messages: Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities.
messages: Mitochondrion matrix
messages: Monomer.

31033:LOC101065443
gene id: 31033:LOC101065443
uniprot id: H2TTX5
names: Similarity
messages: Belongs to the S-100 family.

31033:apoa-i
gene id: 31033:apoa-i
uniprot id: Q5KSU5
names: Similarity
messages: Belongs to the apolipoprotein A1/A4/E family.

31033:LOC101073316
gene id: 31033:LOC101073316
uniprot id: H2TCV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. JAK subfamily.
messages: Endomembrane system

31033:LOC101073986
gene id: 31033:LOC101073986
uniprot id: H2U252
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1 family. Plasminogen subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular space

31033:rspo3
gene id: 31033:rspo3
uniprot id: A0A674NDD3
uniprot id: H2S9X6
names: Similarity
messages: Belongs to the R-spondin family.

31033:KEF89 p04
gene id: 31033:KEF89_p04
uniprot id: Q8HCV6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.
messages: Membrane
messages: Mitochondrion membrane

31033:LOC101074318
gene id: 31033:LOC101074318
uniprot id: P53483
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
names: Tissue Specificity
messages: Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.
messages: Belongs to the actin family.
messages: Oxidation of Met-45 and Met-48 by MICALs (mical1, mical2 or mical3) to form methionine sulfoxide promotes actin filament depolymerization. Mical1 and mical2 produce the (R)-S-oxide form. The (R)-S-oxide form is reverted by msrb1 and msrb2, which promote actin repolymerization (By similarity).
messages: Polymerization of globular actin (G-actin) leads to a structural filament (F-actin) in the form of a two-stranded helix. Each actin can bind to 4 others.
messages: Predominantly expressed in testis.
messages: cytoskeleton

31033:LOC101064641
gene id: 31033:LOC101064641
uniprot id: A0A674NWA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the potassium channel HCN family.
messages: Cell membrane
messages: Membrane

31033:tlcd1
gene id: 31033:tlcd1
uniprot id: A0A3B5KG49
names: Subcellular Location Annotation
messages: Membrane

31033:casp3
gene id: 31033:casp3
uniprot id: Q8JGM9
names: Similarity
messages: Belongs to the peptidase C14A family.

31033:htr5a
gene id: 31033:htr5a
uniprot id: H2V9C0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

31033:golt1b
gene id: 31033:golt1b
uniprot id: A0A674PEC9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GOT1 family.
messages: Golgi apparatus membrane
messages: May be involved in fusion of ER-derived transport vesicles with the Golgi complex.
messages: Membrane

31033:rpl37
gene id: 31033:rpl37
uniprot id: H2VAM2
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL37 family.
messages: Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.

31033:l3hypdh
gene id: 31033:l3hypdh
uniprot id: H2TCH7
names: Similarity
messages: Belongs to the proline racemase family.

31033:LOC101071742
gene id: 31033:LOC101071742
uniprot id: H2V550
names: Similarity
messages: Belongs to the cytochrome P450 family.

31033:rtn2
gene id: 31033:rtn2
uniprot id: Q4G5X4
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

31033:dynlt1
gene id: 31033:dynlt1
uniprot id: A0A674N323
names: Similarity
messages: Belongs to the dynein light chain Tctex-type family.

31033:LOC101070694
gene id: 31033:LOC101070694
uniprot id: H2RUY8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H4 family.
messages: Chromosome
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

31033:LOC101077259
gene id: 31033:LOC101077259
uniprot id: H2S6P5
names: Similarity
messages: Belongs to the mTERF family.

31033:padi2
gene id: 31033:padi2
uniprot id: A0A674PMQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein arginine deiminase family.
messages: Catalyzes the deimination of arginine residues of proteins.
messages: Cytoplasm

31033:tdo2
gene id: 31033:tdo2
uniprot id: H2UT80
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tryptophan 2,3-dioxygenase family.
messages: Binds 1 heme group per subunit.
messages: Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L-tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.
messages: Homotetramer. Dimer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

31033:LOC101071453
gene id: 31033:LOC101071453
uniprot id: H2UWJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the X(+)/potassium ATPases subunit beta family.
messages: Membrane
messages: This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane.

31033:LOC101072056
gene id: 31033:LOC101072056
uniprot id: H2UFP4
names: Subcellular Location Annotation
messages: Secreted
messages: Synapse

31033:rnps1
gene id: 31033:rnps1
uniprot id: H2TA89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the splicing factor SR family.
messages: Nucleus speckle

31033:ftsj1
gene id: 31033:ftsj1
uniprot id: H2UWE1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. TRM7 subfamily.
messages: Cytoplasm
messages: Methylates the 2'-O-ribose of nucleotides at positions 32 and 34 of the tRNA anticodon loop of substrate tRNAs.

31033:LOC101073562
gene id: 31033:LOC101073562
uniprot id: H2RVM6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cyclin family. Cyclin AB subfamily.
messages: Belongs to the cyclin family. Cyclin D subfamily.
messages: Cytoplasm
messages: Essential for the control of the cell cycle at the G2/M (mitosis) transition.
messages: Interacts with the CDK1 protein kinase to form a serine/threonine kinase holoenzyme complex also known as maturation promoting factor (MPF). The cyclin subunit imparts substrate specificity to the complex.
messages: Nucleus

31033:LOC101064562
gene id: 31033:LOC101064562
uniprot id: A0A3B5KGR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dwarfin/SMAD family.
messages: Cytoplasm
messages: Nucleus

31033:LOC101062687
gene id: 31033:LOC101062687
uniprot id: A0A3B5K9Z8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the hepcidin family.
messages: Secreted

31033:cav2
gene id: 31033:cav2
uniprot id: Q9YGM9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the caveolin family.
messages: Cell membrane
messages: Golgi apparatus membrane
messages: Homooligomer.
messages: May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity).
messages: caveola

31033:adam23
gene id: 31033:adam23
uniprot id: A0A674N1M2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

31033:ppt1
gene id: 31033:ppt1
uniprot id: A0A674NCV2
names: Similarity
messages: Belongs to the palmitoyl-protein thioesterase family.

31033:il6st
gene id: 31033:il6st
uniprot id: H2TZE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type I cytokine receptor family. Type 2 subfamily.
messages: Membrane

31033:cblb
gene id: 31033:cblb
uniprot id: H2RM67
names: Domain
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: E3 ubiquitin-protein ligase which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, and transfers it to substrates, generally promoting their degradation by the proteasome.
messages: The N-terminus is composed of the phosphotyrosine binding (PTB) domain, a short linker region and the RING-type zinc finger. The PTB domain, which is also called TKB (tyrosine kinase binding) domain, is composed of three different subdomains: a four-helix bundle (4H), a calcium-binding EF hand and a divergent SH2 domain.

31033:ptk2b
gene id: 31033:ptk2b
uniprot id: H2T8Q7
names: Subcellular Location Annotation
messages: Cell membrane
messages: focal adhesion

31033:ficd
gene id: 31033:ficd
uniprot id: H2UGZ8
names: Similarity
messages: Belongs to the fic family.

31033:LOC101076944
gene id: 31033:LOC101076944
uniprot id: A0A3B5KGD9
uniprot id: A0A674NH81
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

31033:atp23
gene id: 31033:atp23
uniprot id: A0A3B5K2B9
names: Similarity
messages: Belongs to the peptidase M76 family.

31033:LOC101062328
gene id: 31033:LOC101062328
uniprot id: A0A3B5KKG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the myelin basic protein family.
messages: Myelin membrane

31033:ak1
gene id: 31033:ak1
uniprot id: H2SWI8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family. AK1 subfamily.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Also displays broad nucleoside diphosphate kinase activity. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Monomer.

31033:ing3
gene id: 31033:ing3
uniprot id: A0A3B5KM17
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ING family.
messages: Component of an histone acetyltransferase complex.
messages: Component of an histone acetyltransferase complex. Interacts with H3K4me3 and to a lesser extent with H3K4me2.
messages: Nucleus
messages: The PHD-type zinc finger mediates the binding to H3K4me3.

31033:rflna
gene id: 31033:rflna
uniprot id: A0A674PRQ8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Refilin family.
messages: Interacts with FLNA and FLNB.
messages: cytoskeleton

31033:aptx
gene id: 31033:aptx
uniprot id: P61800
names: Domain
names: Function
names: Subcellular Location Annotation
messages: DNA-binding protein involved in single-strand DNA break repair, double-strand DNA break repair and base excision repair. Resolves abortive DNA ligation intermediates formed either at base excision sites, or when DNA ligases attempt to repair non-ligatable breaks induced by reactive oxygen species. Catalyzes the release of adenylate groups covalently linked to 5'-phosphate termini, resulting in the production of 5'-phosphate termini that can be efficiently rejoined. Also able to hydrolyze adenosine 5'-monophosphoramidate (AMP-NH(2)) and diadenosine tetraphosphate (AppppA), but with lower catalytic activity (By similarity). Likewise, catalyzes the release of 3'-linked guanosine (DNAppG) and inosine (DNAppI) from DNA, but has higher specific activity with 5'-linked adenosine (AppDNA) (By similarity).
messages: The C2H2-type zinc finger mediates DNA-binding.
messages: The HIT domain is required for enzymatic activity.
messages: The histidine triad, also called HIT motif, forms part of the binding loop for the alpha-phosphate of purine mononucleotide.
messages: nucleolus
messages: nucleoplasm

31033:zdhhc3
gene id: 31033:zdhhc3
uniprot id: H2T6R5
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

31033:eif4e2
gene id: 31033:eif4e2
uniprot id: H2UJV2
names: Similarity
messages: Belongs to the eukaryotic initiation factor 4E family.

31033:ccdc86
gene id: 31033:ccdc86
uniprot id: A0A3B5K034
names: Subcellular Location Annotation
messages: Nucleus

31033:LOC101080081
gene id: 31033:LOC101080081
uniprot id: A0A3B5KGD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Membrane
messages: cis-Golgi network membrane

31033:LOC101070983
gene id: 31033:LOC101070983
uniprot id: H2S4Z2
names: Similarity
names: Subunit
messages: Belongs to the 14-3-3 family.
messages: Homodimer, and heterodimer with other family members.

31033:LOC101068925
gene id: 31033:LOC101068925
uniprot id: A0A674MYD4
uniprot id: H2ULZ5
uniprot id: H2ULZ8
names: Function
names: Similarity
messages: Belongs to the troponin T family.
messages: Troponin T is the tropomyosin-binding subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.

31033:pigx
gene id: 31033:pigx
uniprot id: A0A3B5KB36
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGX family.
messages: Endoplasmic reticulum membrane
messages: Essential component of glycosylphosphatidylinositol-mannosyltransferase 1 which transfers the first of the 4 mannoses in the GPI-anchor precursors during GPI-anchor biosynthesis.

31033:slc39a1
gene id: 31033:slc39a1
uniprot id: Q6QQT1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Tissue Specificity
messages: Belongs to the ZIP transporter (TC 2.A.5) family.
messages: Cell membrane
messages: Highest levels in ovary, lower levels in intestine and gill, barely detected in kidney.
messages: Mediates zinc uptake.

31033:LOC101078847
gene id: 31033:LOC101078847
uniprot id: H2TNP7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphatidyl serine synthase family.
messages: Catalyzes a base-exchange reaction in which the polar head group of phosphatidylethanolamine (PE) is replaced by L-serine.
messages: Endoplasmic reticulum membrane
messages: Membrane

31033:fkbp6
gene id: 31033:fkbp6
uniprot id: H2UEI3
names: Function
names: Similarity
messages: Belongs to the FKBP6 family.
messages: Co-chaperone required during spermatogenesis to repress transposable elements and prevent their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons. Acts as a co-chaperone via its interaction with HSP90 and is required for the piRNA amplification process, the secondary piRNA biogenesis. May be required together with HSP90 in removal of 16 nucleotide ping-pong by-products from Piwi complexes, possibly facilitating turnover of Piwi complexes.

31033:fam13c
gene id: 31033:fam13c
uniprot id: A0A674MYR2
names: Similarity
messages: Belongs to the FAM13 family.

31033:LOC101076602
gene id: 31033:LOC101076602
uniprot id: H2VDF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the hcp beta-lactamase family.
messages: Mitochondrion intermembrane space

31033:LOC777959
gene id: 31033:LOC777959
uniprot id: Q5IRB0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the stanniocalcin family.
messages: Homodimer; disulfide-linked.
messages: Its primary function is the prevention of hypercalcemia. Upon release into the circulation, it lowers calcium transport by the gills, thereby reducing its rate of influx from the environment into the extracellular compartment. STC also stimulates phosphate reabsorption by renal proximal tubules. The consequence of this action is increased levels of plasma phosphate, which combines with excess calcium and promotes its disposal into bone and scales.

31033:ing2
gene id: 31033:ing2
uniprot id: A0A674NND1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ING family.
messages: Component of an histone acetyltransferase complex.
messages: Component of an histone acetyltransferase complex. Interacts with H3K4me3 and to a lesser extent with H3K4me2.
messages: Nucleus
messages: The PHD-type zinc finger mediates the binding to H3K4me3.

31033:ppm1f
gene id: 31033:ppm1f
uniprot id: H2SC72
names: Similarity
messages: Belongs to the PP2C family.

31033:a3galt2
gene id: 31033:a3galt2
uniprot id: H2UKJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 6 family.
messages: Membrane

31033:LOC105416438
gene id: 31033:LOC105416438
uniprot id: H2TLP9
names: Function
names: Similarity
messages: Belongs to the parvalbumin family.
messages: In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions.

31033:apoa-iv1
gene id: 31033:apoa-iv1
uniprot id: Q5KSU4
names: Similarity
messages: Belongs to the apolipoprotein A1/A4/E family.

31033:lzic
gene id: 31033:lzic
uniprot id: H2TSE0
names: Similarity
messages: Belongs to the CTNNBIP1 family.

31033:LOC101078984
gene id: 31033:LOC101078984
uniprot id: A0A3B5KMQ9
names: Similarity
messages: Belongs to the ANP32 family.

31033:samd8
gene id: 31033:samd8
uniprot id: H2UD38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sphingomyelin synthase family.
messages: Membrane

31033:nsun6
gene id: 31033:nsun6
uniprot id: H2T814
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

31033:LOC101073337
gene id: 31033:LOC101073337
uniprot id: A0A674NH25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neuropeptide B/W family.
messages: Secreted

31033:tpra1
gene id: 31033:tpra1
uniprot id: A0A674MNX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0359 family.
messages: Membrane

31033:vps36
gene id: 31033:vps36
uniprot id: A0A3B5KFY8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the VPS36 family.
messages: Component of the ESCRT-II complex (endosomal sorting complex required for transport II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs.
messages: Component of the endosomal sorting complex required for transport II (ESCRT-II).
messages: Cytoplasm
messages: Endosome

31033:setd7
gene id: 31033:setd7
uniprot id: H2T9P8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SET7 subfamily.
messages: Chromosome
messages: Nucleus

31033:LOC101079909
gene id: 31033:LOC101079909
uniprot id: H2V4M7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

31033:LOC101066478
gene id: 31033:LOC101066478
uniprot id: A0A3B5JZM5
names: Subcellular Location Annotation
messages: Nucleus

31033:hao1
gene id: 31033:hao1
uniprot id: H2TDV8
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

31033:il17d
gene id: 31033:il17d
uniprot id: D4AHP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-17 family.
messages: Secreted

31033:LOC101076622
gene id: 31033:LOC101076622
uniprot id: H2RUY8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H4 family.
messages: Chromosome
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

31033:eif5a
gene id: 31033:eif5a
uniprot id: H2TY85
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eIF-5A family.
messages: Endoplasmic reticulum membrane
messages: eIF-5A seems to be the only eukaryotic protein to have a hypusine residue which is a post-translational modification of a lysine by the addition of a butylamino group.
messages: mRNA-binding protein involved in translation elongation. Has an important function at the level of mRNA turnover, probably acting downstream of decapping. Critical for the efficient synthesis of peptide bonds between consecutive proline residues. Can resolve ribosomal stalling caused by consecutive prolines during translation. Involved in actin dynamics and cell cycle progression, mRNA decay and probably in a pathway involved in stress response and maintenance of cell wall integrity. Functions as a regulator of apoptosis.

31033:cacnb1
gene id: 31033:cacnb1
uniprot id: A0A674N726
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calcium channel beta subunit family.
messages: Membrane
messages: sarcolemma

31033:LOC101076531
gene id: 31033:LOC101076531
uniprot id: A0A674NYQ1
names: Similarity
messages: Belongs to the thymidylate kinase family.

31033:c9h11orf58
gene id: 31033:c9h11orf58
uniprot id: H2ULF5
names: Similarity
messages: Belongs to the SMAP family.

31033:LOC101072777
gene id: 31033:LOC101072777
uniprot id: A0A3B5K0S9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: GTP-binding protein involved in protein trafficking; modulates vesicle budding and uncoating within the Golgi apparatus.
messages: Golgi apparatus

31033:LOC101067916
gene id: 31033:LOC101067916
uniprot id: H2T4W3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

31033:LOC101075000
gene id: 31033:LOC101075000
uniprot id: H2UAN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC8 subfamily.
messages: Cell membrane
messages: Membrane

31033:pde5a
gene id: 31033:pde5a
uniprot id: A0A674P1B4
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

31033:LOC101072553
gene id: 31033:LOC101072553
uniprot id: H2V0H6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

31033:LOC101077200
gene id: 31033:LOC101077200
uniprot id: P53480
names: Function
names: Miscellaneous
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
names: Tissue Specificity
messages: Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.
messages: Belongs to the actin family.
messages: In vertebrates 3 main groups of actin isoforms, alpha, beta and gamma have been identified. The alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. The beta and gamma actins coexist in most cell types as components of the cytoskeleton and as mediators of internal cell motility.
messages: Monomethylation at Lys-86 (K86me1) regulates actin-myosin interaction and actomyosin-dependent processes. Demethylation by ALKBH4 is required for maintaining actomyosin dynamics supporting normal cleavage furrow ingression during cytokinesis and cell migration.
messages: Oxidation of Met-46 and Met-49 by MICALs (MICAL1, MICAL2 or MICAL3) to form methionine sulfoxide promotes actin filament depolymerization. MICAL1 and MICAL2 produce the (R)-S-oxide form. The (R)-S-oxide form is reverted by MSRB1 and MSRB2, which promotes actin repolymerization.
messages: Polymerization of globular actin (G-actin) leads to a structural filament (F-actin) in the form of a two-stranded helix. Each actin can bind to 4 others.
messages: Predominantly expressed in heart. Lower levels in skeletal muscle and skin.
messages: There are three genes coding for cardiac actin in Fugu.
messages: cytoskeleton

31033:LOC101070635
gene id: 31033:LOC101070635
uniprot id: A0A674NBA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.
messages: Membrane

31033:itfg1
gene id: 31033:itfg1
uniprot id: H2TIZ6
names: Similarity
messages: Belongs to the TIP family.

31033:cdh22
gene id: 31033:cdh22
uniprot id: A0A674MLF9
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

31033:pcdhac2
gene id: 31033:pcdhac2
uniprot id: A4KCG4
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain.

31033:LOC101079172
gene id: 31033:LOC101079172
uniprot id: A0A3B5JYB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
messages: Nucleus

31033:st3gal1
gene id: 31033:st3gal1
uniprot id: Q702S2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

31033:LOC101067486
gene id: 31033:LOC101067486
uniprot id: H2TIB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR3 subfamily.
messages: Nucleus

31033:rnf170
gene id: 31033:rnf170
uniprot id: H2RNU7
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

31033:LOC101072310
gene id: 31033:LOC101072310
uniprot id: A0A674NGP6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.

31033:LOC101073251
gene id: 31033:LOC101073251
uniprot id: H2UPT9
names: Similarity
messages: Belongs to the YOS1 family.

31033:fbln7
gene id: 31033:fbln7
uniprot id: H2U6E6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

31033:hmgcr
gene id: 31033:hmgcr
uniprot id: H2U9D0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HMG-CoA reductase family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Peroxisome membrane

31033:kcmf1
gene id: 31033:kcmf1
uniprot id: H2RP51
names: Function
names: Similarity
messages: Belongs to the KCMF1 family.
messages: Has intrinsic E3 ubiquitin ligase activity and promotes ubiquitination.

31033:lgi2
gene id: 31033:lgi2
uniprot id: Q1EGJ9
names: Subcellular Location Annotation
messages: Secreted

31033:pomt1
gene id: 31033:pomt1
uniprot id: A0A674P618
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 39 family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins.

31033:sox2
gene id: 31033:sox2
uniprot id: Q6WNU1
names: Subcellular Location Annotation
messages: Nucleus

31033:cacnb4.1
gene id: 31033:cacnb4.1
uniprot id: A0A674PE22
uniprot id: B6IDE9
names: Similarity
messages: Belongs to the calcium channel beta subunit family.

31033:alkal2
gene id: 31033:alkal2
uniprot id: A0A3B5K4D6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ALKAL family.
messages: Secreted

31033:LOC101073419
gene id: 31033:LOC101073419
uniprot id: A0A674MB33
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 13 family.
messages: Golgi apparatus membrane
messages: Initiates complex N-linked carbohydrate formation. Essential for the conversion of high-mannose to hybrid and complex N-glycans.
messages: Membrane
messages: The cofactor is mostly bound to the substrate.

31033:txnl4a
gene id: 31033:txnl4a
uniprot id: H2UEM8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DIM1 family.
messages: Nucleus
messages: Plays role in pre-mRNA splicing.

31033:LOC101073052
gene id: 31033:LOC101073052
uniprot id: H2V4H5
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

31033:LOC101063187
gene id: 31033:LOC101063187
uniprot id: H2V126
names: Similarity
messages: Belongs to the peptidase M16 family.

31033:tbp
gene id: 31033:tbp
uniprot id: A6H913
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TBP family.
messages: Nucleus

31033:LOC101065852
gene id: 31033:LOC101065852
uniprot id: H2RVY7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b560 family.
messages: Component of complex II composed of four subunits: the flavoprotein (FP) SDHA, iron-sulfur protein (IP) SDHB, and a cytochrome b560 composed of SDHC and SDHD.
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).

31033:creld1
gene id: 31033:creld1
uniprot id: A0A3B5KI01
names: Caution
names: Similarity
messages: Belongs to the CRELD family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

31033:bsx
gene id: 31033:bsx
uniprot id: A0A674N5P6
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

31033:ssbp1
gene id: 31033:ssbp1
uniprot id: H2U9B8
names: Subcellular Location Annotation
messages: mitochondrion nucleoid

31033:LOC101077101
gene id: 31033:LOC101077101
uniprot id: H2UFN1
names: Similarity
messages: Belongs to the nucleosome assembly protein (NAP) family.

31033:LOC101065677
gene id: 31033:LOC101065677
uniprot id: H2UTT3
names: Similarity
messages: Belongs to the LSM14 family.

31033:nkx6-2
gene id: 31033:nkx6-2
uniprot id: H2TKI8
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

31033:LOC101069583
gene id: 31033:LOC101069583
uniprot id: H2UKF0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor Fz/Smo family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

31033:rtn1
gene id: 31033:rtn1
uniprot id: A0A674PN99
uniprot id: Q4G5X5
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

31033:crhbp
gene id: 31033:crhbp
uniprot id: Q24JN9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CRF-binding protein family.
messages: Binds CRF and inactivates it. May prevent inappropriate pituitary-adrenal stimulation in pregnancy.
messages: Secreted

31033:gdnf
gene id: 31033:gdnf
uniprot id: H2UC25
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TGF-beta family. GDNF subfamily.
messages: Homodimer; disulfide-linked.
messages: Neurotrophic factor that enhances survival and morphological differentiation of dopaminergic neurons and increases their high-affinity dopamine uptake.
messages: Secreted

31033:LOC100049638
gene id: 31033:LOC100049638
uniprot id: A0S0K8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: axon
messages: dendrite

31033:ip6k2
gene id: 31033:ip6k2
uniprot id: A0A3B5KG02
names: Similarity
messages: Belongs to the inositol phosphokinase (IPK) family.

31033:LOC101073532
gene id: 31033:LOC101073532
uniprot id: A0A674PPI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPOT14 family.
messages: Cytoplasm
messages: Nucleus

31033:vdac3
gene id: 31033:vdac3
uniprot id: A0A674NVG0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic mitochondrial porin family.
messages: Forms a channel through the mitochondrial outer membrane that allows diffusion of small hydrophilic molecules.
messages: Interacts with ARMC12 in a TBC1D21-dependent manner.
messages: Mitochondrion outer membrane

31033:cstf1
gene id: 31033:cstf1
uniprot id: H2SA09
names: Subcellular Location Annotation
messages: Nucleus

31033:npy8ar
gene id: 31033:npy8ar
uniprot id: A7XY86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

31033:foxp2
gene id: 31033:foxp2
uniprot id: V6F872
names: Subcellular Location Annotation
messages: Nucleus

31033:gal3st1
gene id: 31033:gal3st1
uniprot id: H2UV08
names: Similarity
messages: Belongs to the galactose-3-O-sulfotransferase family.

31033:LOC101078807
gene id: 31033:LOC101078807
uniprot id: H2SFC9
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

31033:grk7
gene id: 31033:grk7
uniprot id: H2RNG0
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.

31033:LOC101070321
gene id: 31033:LOC101070321
uniprot id: H2TUF5
names: Similarity
messages: Belongs to the SNF7 family.

31033:LOC101064870
gene id: 31033:LOC101064870
uniprot id: A0A674NQ90
uniprot id: H2UA29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the requiem/DPF family.
messages: Nucleus

31033:march4
gene id: 31033:march4
uniprot id: H2TSC1
names: Subcellular Location Annotation
messages: Membrane

31033:LOC101073636
gene id: 31033:LOC101073636
uniprot id: A0A674NZA0
names: Similarity
messages: Belongs to the NAD kinase family.

31033:f10
gene id: 31033:f10
uniprot id: Q804W9
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular space

31033:LOC101063201
gene id: 31033:LOC101063201
uniprot id: H2UX10
names: Similarity
messages: Belongs to the protein kinase superfamily.

31033:tbx15
gene id: 31033:tbx15
uniprot id: H2SAB5
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

31033:actl6a
gene id: 31033:actl6a
uniprot id: A0A674MLM2
names: Similarity
messages: Belongs to the actin family.

31033:ddx1
gene id: 31033:ddx1
uniprot id: H2UTK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. DDX1 subfamily.
messages: Cytoplasmic granule

31033:slc6a1
gene id: 31033:slc6a1
uniprot id: A0A674P5P7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

31033:osbpl8
gene id: 31033:osbpl8
uniprot id: A0A674PM67
names: Similarity
messages: Belongs to the OSBP family.

31033:snrnp27
gene id: 31033:snrnp27
uniprot id: H2ULS1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SNUT3 family.
messages: May play a role in mRNA splicing.
messages: Nucleus
messages: Part of a tri-snRNP complex.

31033:cpox
gene id: 31033:cpox
uniprot id: A0A3B5K803
names: Similarity
names: Subunit
messages: Belongs to the aerobic coproporphyrinogen-III oxidase family.
messages: Homodimer.

31033:chac1
gene id: 31033:chac1
uniprot id: A0A674PRH6
names: Function
names: Similarity
messages: Belongs to the gamma-glutamylcyclotransferase family. ChaC subfamily.
messages: Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides.

31033:plac8
gene id: 31033:plac8
uniprot id: A0A674NIN5
names: Similarity
messages: Belongs to the cornifelin family.

31033:cdkn1b
gene id: 31033:cdkn1b
uniprot id: A0A3B5KDR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDI family.
messages: Cytoplasm
messages: Endosome
messages: Nucleus

31033:LOC101064309
gene id: 31033:LOC101064309
uniprot id: A0A3B5KJB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unc-93 family.
messages: Membrane

31033:tpm1
gene id: 31033:tpm1
uniprot id: Q805D1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tropomyosin family.
messages: cytoskeleton

31033:pcmtd1
gene id: 31033:pcmtd1
uniprot id: A0A3B5KG40
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

31033:stam
gene id: 31033:stam
uniprot id: H2TEE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STAM family.
messages: Early endosome membrane

31033:taf8
gene id: 31033:taf8
uniprot id: H2TD69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF8 family.
messages: Nucleus

31033:LOC101075977
gene id: 31033:LOC101075977
uniprot id: H2SZZ2
names: Similarity
messages: Belongs to the peptidase C1 family.

31033:LOC101067626
gene id: 31033:LOC101067626
uniprot id: H2TMN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Deltex family.
messages: Cytoplasm

31033:mrps11
gene id: 31033:mrps11
uniprot id: A0A3B5KKP4
names: Similarity
messages: Belongs to the universal ribosomal protein uS11 family.

31033:LOC101070469
gene id: 31033:LOC101070469
uniprot id: H2VDM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DMRT family.
messages: Nucleus

31033:LOC101067147
gene id: 31033:LOC101067147
uniprot id: H2V2F3
names: Subcellular Location Annotation
messages: Nucleus

31033:LOC101078933
gene id: 31033:LOC101078933
uniprot id: H2T3T0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

31033:camk1g
gene id: 31033:camk1g
uniprot id: A0A3B5KIY8
names: Similarity
messages: Belongs to the protein kinase superfamily.

31033:usp44
gene id: 31033:usp44
uniprot id: A0A3B5KGU8
names: Similarity
messages: Belongs to the peptidase C19 family.

31033:LOC105416476
gene id: 31033:LOC105416476
uniprot id: A0A674MEW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the actinoporin family. Sea anemone subfamily.
messages: Cell membrane
messages: Membrane
messages: Nematocyst
messages: Target cell membrane

31033:snx30
gene id: 31033:snx30
uniprot id: H2SUU2
names: Similarity
messages: Belongs to the sorting nexin family.

31033:sh3rf3
gene id: 31033:sh3rf3
uniprot id: H2SHK6
names: Similarity
messages: Belongs to the SH3RF family.

31033:LOC101061652
gene id: 31033:LOC101061652
uniprot id: A0A3B5KEI5
names: Similarity
names: Subunit
messages: Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.
messages: Homotetramer.

31033:tas1r3
gene id: 31033:tas1r3
uniprot id: Q2MHJ8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

31033:LOC101068736
gene id: 31033:LOC101068736
uniprot id: H2UYT2
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL19 family.
messages: Component of the large ribosomal subunit.

31033:capzb
gene id: 31033:capzb
uniprot id: H2TJF7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the F-actin-capping protein beta subunit family.
messages: F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
messages: Heterodimer of an alpha and a beta subunit.
messages: cytoskeleton

31033:LOC101064136
gene id: 31033:LOC101064136
uniprot id: H2U2D8
names: Similarity
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.

31033:LOC101077175
gene id: 31033:LOC101077175
uniprot id: H2SHP1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Binds 2 magnesium ions per subunit. Is also active with manganese (in vitro).
messages: Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.
messages: Membrane

31033:LOC101078354
gene id: 31033:LOC101078354
uniprot id: A0A674M998
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HesB/IscA family.
messages: Mitochondrion

31033:lhx5
gene id: 31033:lhx5
uniprot id: H2VCV9
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

31033:ap3s1
gene id: 31033:ap3s1
uniprot id: H2V0X1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes small subunit family.
messages: Cytoplasmic vesicle membrane
messages: Membrane
messages: Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals.

31033:get3
gene id: 31033:get3
uniprot id: H2SVU0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATPase required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. Subsequently, the homodimer reverts towards the open dimer state, lowering its affinity for the membrane-bound receptor, and returning it to the cytosol to initiate a new round of targeting.
messages: Belongs to the arsA ATPase family.
messages: Cytoplasm
messages: Endoplasmic reticulum
messages: Homodimer.

31033:derl2
gene id: 31033:derl2
uniprot id: A0A3B5JXJ8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the derlin family.
messages: Endoplasmic reticulum membrane
messages: Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

31033:gabrg2
gene id: 31033:gabrg2
uniprot id: A0A674N4Q3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

31033:LOC101070269
gene id: 31033:LOC101070269
uniprot id: A0A674PBT7
names: Subcellular Location Annotation
messages: Membrane

31033:LOC101076002
gene id: 31033:LOC101076002
uniprot id: A0A674P044
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 7 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids.

31033:nsun5
gene id: 31033:nsun5
uniprot id: H2V8F8
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

31033:LOC101076376
gene id: 31033:LOC101076376
uniprot id: A0A674N9Q4
uniprot id: H2TX31
names: Similarity
messages: Belongs to the syntaxin family.

31033:ndufb9
gene id: 31033:ndufb9
uniprot id: A0A674NNR8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed to be not involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I LYR family.
messages: Mammalian complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

31033:kifc3
gene id: 31033:kifc3
uniprot id: H2S1X6
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

31033:LOC101064892
gene id: 31033:LOC101064892
uniprot id: Q8UWL6
names: Subcellular Location Annotation
messages: Nucleus

31033:slc7a4
gene id: 31033:slc7a4
uniprot id: H2STN9
names: Subcellular Location Annotation
messages: Membrane

31033:llgl2
gene id: 31033:llgl2
uniprot id: H2SZM3
names: Similarity
messages: Belongs to the WD repeat L(2)GL family.

31033:LOC101075171
gene id: 31033:LOC101075171
uniprot id: H2SCV7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IRF family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

31033:LOC101074632
gene id: 31033:LOC101074632
uniprot id: H2VET9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCF/LEF family.
messages: Nucleus

31033:LOC101064355
gene id: 31033:LOC101064355
uniprot id: A0A3B5K855
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPIN/STSY family.
messages: Nucleus

31033:LOC101072451
gene id: 31033:LOC101072451
uniprot id: H2TPS6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

31033:igfbp4
gene id: 31033:igfbp4
uniprot id: B6RNJ3
names: Caution
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Binds IGF2 more than IGF1.
messages: IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

31033:rbm5
gene id: 31033:rbm5
uniprot id: H2T7V2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RBM5/RBM10 family.
messages: Nucleus

31033:cd40
gene id: 31033:cd40
uniprot id: B8YI09
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

31033:apoA-IV4
gene id: 31033:apoA-IV4
uniprot id: Q5KSU1
names: Similarity
messages: Belongs to the apolipoprotein A1/A4/E family.

31033:LOC101072783
gene id: 31033:LOC101072783
uniprot id: H2U0D4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Cell membrane
messages: Protein transport.

31033:mmp2
gene id: 31033:mmp2
uniprot id: Q4JF84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M10A family.
messages: extracellular matrix

31033:jpt2
gene id: 31033:jpt2
uniprot id: I7KJP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the JUPITER family.
messages: Cytoplasm
messages: Nucleus

31033:evx1
gene id: 31033:evx1
uniprot id: Q1KL23
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

31033:LOC101071146
gene id: 31033:LOC101071146
uniprot id: Q8QFS1
names: Similarity
messages: Belongs to the centrin family.

31033:sh3bgrl3
gene id: 31033:sh3bgrl3
uniprot id: A0A674MR35
names: Similarity
messages: Belongs to the SH3BGR family.

31033:LOC101063190
gene id: 31033:LOC101063190
uniprot id: H2TX46
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP, AMP, or fructose 2,6-bisphosphate, and allosterically inhibited by ATP or citrate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade "E" sub-subfamily.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homo- and heterotetramers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

31033:ddx49
gene id: 31033:ddx49
uniprot id: A0A3B5KPM4
names: Similarity
messages: Belongs to the DEAD box helicase family.

31033:LOC101072094
gene id: 31033:LOC101072094
uniprot id: H2SJV2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

31033:LOC101079108
gene id: 31033:LOC101079108
uniprot id: A0A674MZ81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CLPTM1 family.
messages: Membrane

31033:mcts1
gene id: 31033:mcts1
uniprot id: H2TI11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCTS1 family.
messages: Cytoplasm

31033:mrpl12
gene id: 31033:mrpl12
uniprot id: A0A3B5KH94
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL12 family.

31033:tcf7
gene id: 31033:tcf7
uniprot id: A0A3B5K058
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCF/LEF family.
messages: Nucleus

31033:LOC101074400
gene id: 31033:LOC101074400
uniprot id: H2UXZ1
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

31033:tspo
gene id: 31033:tspo
uniprot id: A0A674MEV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TspO/BZRP family.
messages: Membrane

31033:cldn8d
gene id: 31033:cldn8d
uniprot id: Q6E5P7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

31033:LOC101072391
gene id: 31033:LOC101072391
uniprot id: A0A3B5KP99
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ephrin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

31033:LOC101072325
gene id: 31033:LOC101072325
uniprot id: H2SAZ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Membrane
messages: The small GTPases Rab are key regulators in vesicle trafficking.

31033:dpy19l4
gene id: 31033:dpy19l4
uniprot id: A0A674N859
uniprot id: H2SXA9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dpy-19 family.
messages: Membrane
messages: Probable C-mannosyltransferase that mediates C-mannosylation of tryptophan residues on target proteins.

31033:LOC101061479
gene id: 31033:LOC101061479
uniprot id: A0A3B5K167
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

31033:LOC101074692
gene id: 31033:LOC101074692
uniprot id: H2UFG2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

31033:LOC101062124
gene id: 31033:LOC101062124
uniprot id: A0A674MAG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 3 family.
messages: Cell membrane
messages: Membrane

31033:LOC101067990
gene id: 31033:LOC101067990
uniprot id: A0A3B5KM38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

31033:LOC101064018
gene id: 31033:LOC101064018
uniprot id: A0A3B5KBU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PPP phosphatase family. PP-1 subfamily.
messages: Cytoplasm

31033:LOC101078069
gene id: 31033:LOC101078069
uniprot id: Q1KKU7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

31033:LOC101075290
gene id: 31033:LOC101075290
uniprot id: H2T8S5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MICOS complex subunit Mic10 family.
messages: Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
messages: Component of the mitochondrial contact site and cristae organizing system (MICOS) complex.
messages: Membrane
messages: Mitochondrion inner membrane

31033:actbb
gene id: 31033:actbb
uniprot id: P53485
names: Function
names: Miscellaneous
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA.
messages: Belongs to the actin family.
messages: In vertebrates 3 main groups of actin isoforms, alpha, beta and gamma have been identified. The alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. The beta and gamma actins coexist in most cell types as components of the cytoskeleton and as mediators of internal cell motility.
messages: Methylation at His-73 by SETD3. Methylation stabilizes actin filaments.
messages: Nucleus
messages: Oxidation of Met-44 and Met-47 by MICALs (mical1, mical2 or mical3) to form methionine sulfoxide promotes actin filament depolymerization. Mical1 and mical2 produce the (R)-S-oxide form. The (R)-S-oxide form is reverted by msrb1 and msrb2, which promote actin repolymerization.
messages: Polymerization of globular actin (G-actin) leads to a structural filament (F-actin) in the form of a two-stranded helix (By similarity). Each actin can bind to 4 others (By similarity).
messages: There are three different beta-cytoplasmic actins in Fugu rubripes.
messages: cytoskeleton

31033:nadk
gene id: 31033:nadk
uniprot id: H2RNY1
names: Similarity
messages: Belongs to the NAD kinase family.

31033:LOC100653418
gene id: 31033:LOC100653418
uniprot id: E9LYZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prominin family.
messages: Membrane
messages: microvillus membrane

31033:plod1
gene id: 31033:plod1
uniprot id: A5A6S1
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane

31033:pld3
gene id: 31033:pld3
uniprot id: H2UXI9
names: Similarity
messages: Belongs to the phospholipase D family.

31033:rps2
gene id: 31033:rps2
uniprot id: H2SWH7
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel. Plays a role in the assembly and function of the 40S ribosomal subunit. Mutations in this protein affects the control of translational fidelity. Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly.

31033:LOC101068604
gene id: 31033:LOC101068604
uniprot id: A0A674MKB0
names: Similarity
messages: Belongs to the glutaminase family.

31033:cnp-2
gene id: 31033:cnp-2
uniprot id: Q805D5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the natriuretic peptide family.
messages: Exhibits natriuretic and vasodepressant activity. Has cGMP-stimulating activity. May help to regulate body fluid homeostasis in a variety of aquatic environments.
messages: Secreted

31033:xkr6
gene id: 31033:xkr6
uniprot id: Q5GH49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XK family.
messages: Membrane

31033:LOC101067616
gene id: 31033:LOC101067616
uniprot id: A0A674PDW8
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

31033:cygb
gene id: 31033:cygb
uniprot id: H2U139
names: Similarity
messages: Belongs to the globin family.

31033:actb
gene id: 31033:actb
uniprot id: P68142
names: Function
names: Miscellaneous
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
names: Tissue Specificity
messages: Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA.
messages: Belongs to the actin family.
messages: In vertebrates 3 main groups of actin isoforms, alpha, beta and gamma have been identified. The alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. The beta and gamma actins coexist in most cell types as components of the cytoskeleton and as mediators of internal cell motility.
messages: Methylation at His-73 by SETD3. Methylation stabilizes actin filaments.
messages: Nucleus
messages: Oxidation of Met-44 and Met-47 by MICALs (mical1, mical2 or mical3) to form methionine sulfoxide promotes actin filament depolymerization. Mical1 and mical2 produce the (R)-S-oxide form. The (R)-S-oxide form is reverted by msrb1 and msrb2, which promote actin repolymerization.
messages: Polymerization of globular actin (G-actin) leads to a structural filament (F-actin) in the form of a two-stranded helix (By similarity). Each actin can bind to 4 others (By similarity).
messages: There are three different beta-cytoplasmic actins in Fugu rubripes.
messages: Widely distributed. Not expressed in skeletal muscle.
messages: cytoskeleton

31033:LOC101077955
gene id: 31033:LOC101077955
uniprot id: H2THG6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TGF-beta family.
messages: Homodimer; disulfide-linked.
messages: Transforming growth factor beta-3 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-3 (TGF-beta-3) chains, which constitute the regulatory and active subunit of TGF-beta-3, respectively.
messages: extracellular matrix

31033:zdhhc5
gene id: 31033:zdhhc5
uniprot id: Q2THV8
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

31033:itga11
gene id: 31033:itga11
uniprot id: H2V0X6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

31033:LOC101073338
gene id: 31033:LOC101073338
uniprot id: A0A674NCA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

31033:LOC101077776
gene id: 31033:LOC101077776
uniprot id: H2T950
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Cell membrane
messages: Membrane

31033:dnmbp
gene id: 31033:dnmbp
uniprot id: H2U900
names: Subcellular Location Annotation
messages: Cell junction
messages: Golgi stack
messages: Synapse
messages: cytoskeleton

31033:dlx6
gene id: 31033:dlx6
uniprot id: H2T261
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

31033:siat5-r
gene id: 31033:siat5-r
uniprot id: Q50J60
uniprot id: Q6KB57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

31033:LOC101078924
gene id: 31033:LOC101078924
uniprot id: Q2PR31
names: Subcellular Location Annotation
messages: Membrane

31033:LOC101064759
gene id: 31033:LOC101064759
uniprot id: H2U885
uniprot id: H2U886
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

31033:ino80
gene id: 31033:ino80
uniprot id: H2U7Y4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATPase component of the INO80 complex which remodels chromatin by shifting nucleosomes and is involved in DNA repair.
messages: Belongs to the SNF2/RAD54 helicase family.
messages: Component of the INO80 chromatin-remodeling complex.
messages: Nucleus
messages: The DBINO region is involved in binding to DNA.

31033:LOC101068869
gene id: 31033:LOC101068869
uniprot id: A0A674MI10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Ras family.
messages: Endosome membrane
messages: Recycling endosome membrane

31033:ccna2
gene id: 31033:ccna2
uniprot id: H2SY68
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cyclin family. Cyclin AB subfamily.
messages: Essential for the control of the cell cycle at the G2/M (mitosis) transition.
messages: Interacts with the CDK1 protein kinase to form a serine/threonine kinase holoenzyme complex also known as maturation promoting factor (MPF). The cyclin subunit imparts substrate specificity to the complex.

31033:eef1g
gene id: 31033:eef1g
uniprot id: A0A674P589
names: Function
names: Subunit
messages: EF-1 is composed of four subunits: alpha, beta, delta, and gamma.
messages: Probably plays a role in anchoring the complex to other cellular components.

31033:ppib
gene id: 31033:ppib
uniprot id: A0A3B5K4E5
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

31033:LOC101077147
gene id: 31033:LOC101077147
uniprot id: H2S6B3
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

31033:rhag-1
gene id: 31033:rhag-1
uniprot id: Q7T3R8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonium transporter (TC 2.A.49) family. Rh subfamily.
messages: Cell membrane
messages: Functions as an ammonia transporter. May play a role in the elimination of ammonia in the gill.
messages: Membrane

31033:LOC101068996
gene id: 31033:LOC101068996
uniprot id: H2UZL2
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

31033:nts
gene id: 31033:nts
uniprot id: H2RTX4
uniprot id: Q5TLU5
names: Similarity
messages: Belongs to the peptidase A1 family.

31033:pde6d
gene id: 31033:pde6d
uniprot id: A0A3B5K321
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PDE6D/unc-119 family.
messages: Cytoplasmic vesicle membrane
messages: Interacts with the prenylated catalytic subunits of PDE6, an oligomer composed of two catalytic chains and two inhibitory chains; has no effect on enzyme activity but promotes the release of the prenylated enzyme from cell membrane.
messages: Promotes the release of prenylated target proteins from cellular membranes. Modulates the activity of prenylated or palmitoylated Ras family members by regulating their subcellular location. Required for normal ciliary targeting of farnesylated target proteins, such as INPP5E. Modulates the subcellular location of target proteins by acting as a GTP specific dissociation inhibitor (GDI). Increases the affinity of ARL3 for GTP by several orders of magnitude. Stabilizes ARL3-GTP by decreasing the nucleotide dissociation rate.
messages: cilium basal body
messages: cytosol

31033:LOC105418776
gene id: 31033:LOC105418776
uniprot id: A0A3B5KCE4
names: Similarity
messages: Belongs to the FAM83 family.

31033:ctdp1
gene id: 31033:ctdp1
uniprot id: A0A674PMH1
uniprot id: H2U7R2
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: This promotes the activity of RNA polymerase II.

31033:znf503
gene id: 31033:znf503
uniprot id: H2S7B1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Elbow/Noc family.
messages: Nucleus

31033:arrdc2
gene id: 31033:arrdc2
uniprot id: H2S8P7
names: Similarity
messages: Belongs to the arrestin family.

31033:nae1
gene id: 31033:nae1
uniprot id: A0A674PQI3
names: Function
names: Similarity
messages: Belongs to the ubiquitin-activating E1 family. ULA1 subfamily.
messages: Regulatory subunit of the dimeric UBA3-NAE1 E1 enzyme. E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M.

31033:LOC101076410
gene id: 31033:LOC101076410
uniprot id: H2SJJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Major role in the synthesis of nucleoside triphosphates other than ATP.
messages: Nucleus
messages: lamellipodium
messages: ruffle

31033:actn3
gene id: 31033:actn3
uniprot id: H2SND8
names: Similarity
messages: Belongs to the alpha-actinin family.

31033:LOC101079816
gene id: 31033:LOC101079816
uniprot id: H2TP17
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
messages: Component of a calcium channel complex consisting of a pore-forming alpha subunit (CACNA1S) and the ancillary subunits CACNB1 or CACNB2, CACNG1 and CACNA2D1. The channel complex contains alpha, beta, gamma and delta subunits in a 1:1:1:1 ratio, i.e. it contains either CACNB1 or CACNB2.
messages: Membrane
messages: Regulatory subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents in skeletal muscle. Regulates channel inactivation kinetics.
messages: sarcolemma

31033:LOC101071984
gene id: 31033:LOC101071984
uniprot id: A0A674NH48
names: Similarity
messages: Belongs to the arrestin family.

31033:LOC101076648
gene id: 31033:LOC101076648
uniprot id: A0A3B5KIF4
names: Function
names: Similarity
messages: Belongs to the cytochrome c oxidase subunit 6B.
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.

31033:braf
gene id: 31033:braf
uniprot id: Q4W6L8
names: Similarity
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. RAF subfamily.

31033:LOC101068879
gene id: 31033:LOC101068879
uniprot id: A0A674MWD0
names: Similarity
messages: Belongs to the PAIP2 family.

31033:LOC101072102
gene id: 31033:LOC101072102
uniprot id: Q1KKY3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

31033:trmt2a
gene id: 31033:trmt2a
uniprot id: H2UCA1
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

31033:LOC101066055
gene id: 31033:LOC101066055
uniprot id: H2TPI5
names: Similarity
messages: Belongs to the YY transcription factor family.

31033:evc
gene id: 31033:evc
uniprot id: Q671A1
names: Subcellular Location Annotation
messages: Membrane
messages: cilium basal body
messages: cilium membrane

31033:LOC101061355
gene id: 31033:LOC101061355
uniprot id: H2UN98
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

31033:LOC101066365
gene id: 31033:LOC101066365
uniprot id: H2RP75
names: Subcellular Location Annotation
messages: extracellular matrix

31033:edc3
gene id: 31033:edc3
uniprot id: H2V3H2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EDC3 family.
messages: P-body

31033:stn1
gene id: 31033:stn1
uniprot id: H2TIM5
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Component of the CST complex proposed to act as a specialized replication factor promoting DNA replication under conditions of replication stress or natural replication barriers such as the telomere duplex. The CST complex binds single-stranded DNA with high affinity in a sequence-independent manner, while isolated subunits bind DNA with low affinity by themselves. Initially the CST complex has been proposed to protect telomeres from DNA degradation. However, the CST complex has been shown to be involved in several aspects of telomere replication.
messages: Component of the CST complex.
messages: Nucleus
messages: telomere

31033:cftr
gene id: 31033:cftr
uniprot id: Q9I8E2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the ABC transporter superfamily. ABCC family. CFTR transporter (TC 3.A.1.202) subfamily.
messages: Cell membrane
messages: Early endosome membrane
messages: Endoplasmic reticulum membrane
messages: Endosome membrane
messages: Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer.
messages: Recycling endosome membrane

31033:LOC497075
gene id: 31033:LOC497075
uniprot id: Q5GH48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XK family.
messages: Membrane

31033:LOC101074526
gene id: 31033:LOC101074526
uniprot id: H2THB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calreticulin family.
messages: Endoplasmic reticulum lumen

31033:nxt2
gene id: 31033:nxt2
uniprot id: A0A3B5KFF4
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Has a role in nuclear-cytoplasmic transport of proteins and mRNAs.
messages: Nucleus

31033:slc30a9
gene id: 31033:slc30a9
uniprot id: H2UGY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
messages: Cytoplasmic vesicle
messages: Endoplasmic reticulum
messages: Membrane
messages: Nucleus
messages: Vesicle

31033:taf6
gene id: 31033:taf6
uniprot id: H2UYT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF6 family.
messages: Nucleus

31033:LOC101075224
gene id: 31033:LOC101075224
uniprot id: H2U7M2
names: Function
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Does not have a catalytic activity.

31033:c5h11orf88
gene id: 31033:c5h11orf88
uniprot id: H2RMM0
names: Similarity
messages: Belongs to the HOATZ family.

31033:cask
gene id: 31033:cask
uniprot id: H2TXP5
names: Similarity
messages: Belongs to the MAGUK family.

31033:mmgt1
gene id: 31033:mmgt1
uniprot id: H2SBN1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane magnesium transporter (TC 1.A.67) family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Golgi apparatus membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the endoplasmic reticulum membrane protein complex (EMC) that enables the energy-independent insertion into endoplasmic reticulum membranes of newly synthesized membrane proteins. May be involved in Mg(2+) transport.

31033:arl2bp
gene id: 31033:arl2bp
uniprot id: A0A3B5KEG2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ARL2BP family.
messages: Cytoplasm
messages: Mitochondrion intermembrane space
messages: Nucleus
messages: Plays a role as an effector of the ADP-ribosylation factor-like protein 2, ARL2.
messages: centrosome
messages: cilium basal body

31033:cct2
gene id: 31033:cct2
uniprot id: H2RTX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm

31033:dnm2
gene id: 31033:dnm2
uniprot id: H2UBF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.
messages: cytoskeleton

31033:galnt7
gene id: 31033:galnt7
uniprot id: A0A6D2Y1F8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

31033:LOC101079229
gene id: 31033:LOC101079229
uniprot id: A0A674NVP3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glypican family.
messages: Cell membrane
messages: Cell surface proteoglycan that bears heparan sulfate.

31033:il15
gene id: 31033:il15
uniprot id: Q3SCC8
uniprot id: Q3SCC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-15/IL-21 family.
messages: Secreted

31033:gpr135
gene id: 31033:gpr135
uniprot id: Q7T2L0
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

31033:fam118b
gene id: 31033:fam118b
uniprot id: H2SVP1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM118 family.
messages: Cajal body
messages: May play a role in Cajal bodies formation.

31033:cfap298
gene id: 31033:cfap298
uniprot id: H2T0H0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CFAP298 family.
messages: cilium basal body

31033:mvb12b
gene id: 31033:mvb12b
uniprot id: A0A674NCX7
uniprot id: H2U5D0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MVB12 family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Membrane

31033:LOC101073954
gene id: 31033:LOC101073954
uniprot id: H2SDK7
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family.

31033:klhl40
gene id: 31033:klhl40
uniprot id: H2V745
names: Similarity
names: Subcellular Location Annotation
messages: A band
messages: Belongs to the KLHL40 family.
messages: I band

31033:lclat1
gene id: 31033:lclat1
uniprot id: A0A3B5JVL8
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

31033:srm
gene id: 31033:srm
uniprot id: A0A3B5K8F4
names: Similarity
messages: Belongs to the spermidine/spermine synthase family.

31033:ppil1
gene id: 31033:ppil1
uniprot id: H2UNQ9
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

31033:c21h12orf43
gene id: 31033:c21h12orf43
uniprot id: A0A3B5KF23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CUSTOS family.
messages: Nucleus envelope

31033:LOC101062529
gene id: 31033:LOC101062529
uniprot id: A0A3B5KAZ8
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

31033:LOC101074085
gene id: 31033:LOC101074085
uniprot id: A0A3B5K3E3
names: Similarity
messages: Belongs to the SPIN/STSY family.

31033:LOC101078250
gene id: 31033:LOC101078250
uniprot id: A0A674NW52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

31033:LOC101077171
gene id: 31033:LOC101077171
uniprot id: H2U787
names: Similarity
messages: Belongs to the GADD45 family.

31033:tmem115
gene id: 31033:tmem115
uniprot id: A0A674MWA3
names: Subcellular Location Annotation
messages: Membrane

31033:fgd4
gene id: 31033:fgd4
uniprot id: A0A674MFG5
uniprot id: A0A674NH22
names: Subcellular Location Annotation
messages: cytoskeleton

31033:bgn
gene id: 31033:bgn
uniprot id: H2THK2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily.
messages: May be involved in collagen fiber assembly.
messages: extracellular matrix

31033:LOC101071924
gene id: 31033:LOC101071924
uniprot id: H2S6K8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WFIKKN family.
messages: Membrane

31033:fam219b
gene id: 31033:fam219b
uniprot id: A0A3B5KKD2
names: Similarity
messages: Belongs to the FAM219 family.

31033:LOC101069617
gene id: 31033:LOC101069617
uniprot id: A0A674NPF7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 19 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

31033:tmem50a
gene id: 31033:tmem50a
uniprot id: H2RUS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0220 family.
messages: Membrane

31033:LOC101067527
gene id: 31033:LOC101067527
uniprot id: H2RTM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tdpoz family.
messages: Nucleus speckle

31033:upp2
gene id: 31033:upp2
uniprot id: H2SWA5
names: Function
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family.
messages: Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis.

31033:gsx2
gene id: 31033:gsx2
uniprot id: H2UNF4
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

31033:LOC101071427
gene id: 31033:LOC101071427
uniprot id: H2T8B8
names: Subcellular Location Annotation
messages: Nucleus

31033:LOC101074158
gene id: 31033:LOC101074158
uniprot id: A0A674NSP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CYBC1 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

31033:acvr2b
gene id: 31033:acvr2b
uniprot id: A0A674NFV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane

31033:agbl5
gene id: 31033:agbl5
uniprot id: H2VAP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M14 family.
messages: Midbody
messages: Nucleus
messages: cytosol
messages: spindle

31033:LOC101072045
gene id: 31033:LOC101072045
uniprot id: A0A3B5KLI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

31033:lhx6
gene id: 31033:lhx6
uniprot id: H2SPT4
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

31033:slc1a4
gene id: 31033:slc1a4
uniprot id: H2SMU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

31033:nil1fm
gene id: 31033:nil1fm
uniprot id: A0A3B5JXV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-1 family.
messages: Lysosome
messages: cytosol
messages: extracellular exosome

31033:LOC101061022
gene id: 31033:LOC101061022
uniprot id: H2UWB4
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

31033:med28
gene id: 31033:med28
uniprot id: A0A3B5KCU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 28 family.
messages: Nucleus

31033:tmem178a
gene id: 31033:tmem178a
uniprot id: H2TVP5
names: Similarity
messages: Belongs to the TMEM178 family.

31033:LOC101066901
gene id: 31033:LOC101066901
uniprot id: H2T6V3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP-alpha family.
messages: Endoplasmic reticulum membrane
messages: Heterotetramer of TRAP-alpha, TRAP-beta, TRAP-delta and TRAP-gamma.
messages: Membrane
messages: Shows a remarkable charge distribution with the N-terminus being highly negatively charged, and the cytoplasmic C-terminus positively charged.
messages: TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins. May be involved in the recycling of the translocation apparatus after completion of the translocation process or may function as a membrane-bound chaperone facilitating folding of translocated proteins.

31033:LOC101069347
gene id: 31033:LOC101069347
uniprot id: H2UPF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
messages: Cytoplasm

31033:nthl1
gene id: 31033:nthl1
uniprot id: A0A674PQW9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Nth/MutY family.
messages: Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines.
messages: Binds 1 [4Fe-4S] cluster. The cluster does not appear to play a role in catalysis, but is probably involved in the proper positioning of the enzyme along the DNA strand.
messages: Mitochondrion
messages: Nucleus

31033:fgf6
gene id: 31033:fgf6
uniprot id: H2TMB1
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

31033:LOC101076629
gene id: 31033:LOC101076629
uniprot id: H2T1Y8
names: Similarity
messages: Belongs to the ADP-ribosylglycohydrolase family.

31033:ndufa8
gene id: 31033:ndufa8
uniprot id: H2RPM0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA8 subunit family.
messages: Mitochondrion inner membrane
messages: Mitochondrion intermembrane space

31033:LOC101066450
gene id: 31033:LOC101066450
uniprot id: A0A3B5KDL8
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MNB/DYRK subfamily.

31033:fut4
gene id: 31033:fut4
uniprot id: Q70AH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 10 family.
messages: Golgi stack membrane

31033:LOC101076768
gene id: 31033:LOC101076768
uniprot id: H2RLI6
names: Similarity
messages: Belongs to the G-alpha family. G(q) subfamily.

31033:LOC101070555
gene id: 31033:LOC101070555
uniprot id: H2T9H2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

31033:idh3b
gene id: 31033:idh3b
uniprot id: A0A674NSD9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Heterooligomer of subunits alpha (IDH3A), beta (IDH3B), and gamma (IDH3G) in the apparent ratio of 2:1:1. The heterodimer containing one IDH3A and one IDH3B subunit and the heterodimer containing one IDH3A and one IDH3G subunit assemble into a heterotetramer (which contains two subunits of IDH3A, one of IDH3B and one of IDH3G) and further into the heterooctamer.
messages: Mitochondrion

31033:churc1
gene id: 31033:churc1
uniprot id: H2VAT4
names: Similarity
messages: Belongs to the Churchill family.

31033:LOC101063506
gene id: 31033:LOC101063506
uniprot id: H2T6F9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

31033:LOC101078843
gene id: 31033:LOC101078843
uniprot id: H2UP80
names: Subcellular Location Annotation
messages: Membrane

31033:grk6
gene id: 31033:grk6
uniprot id: H2RQK6
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.

31033:LOC101075938
gene id: 31033:LOC101075938
uniprot id: A0A674M9U3
names: Subcellular Location Annotation
messages: Membrane

31033:LOC101064256
gene id: 31033:LOC101064256
uniprot id: A0A3B5K5U7
names: Similarity
messages: Belongs to the SLBP family.

31033:LOC101077107
gene id: 31033:LOC101077107
uniprot id: H2TQM7
names: Similarity
messages: Belongs to the FMR1 family.

31033:trappc3
gene id: 31033:trappc3
uniprot id: H2UTE5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAPP small subunits family. BET3 subfamily.
messages: Endoplasmic reticulum
messages: Homodimer.
messages: May play a role in vesicular transport from endoplasmic reticulum to Golgi.
messages: cis-Golgi network

31033:imp3
gene id: 31033:imp3
uniprot id: A0A674MEA5
names: Similarity
messages: Belongs to the universal ribosomal protein uS4 family.

31033:LOC101064535
gene id: 31033:LOC101064535
uniprot id: A0A674NH25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neuropeptide B/W family.
messages: Secreted

31033:LOC115246485
gene id: 31033:LOC115246485
uniprot id: A0A674MNM4
names: Subcellular Location Annotation
messages: Membrane

31033:lgi1
gene id: 31033:lgi1
uniprot id: Q1EGK1
names: Subcellular Location Annotation
messages: Secreted

31033:snap23
gene id: 31033:snap23
uniprot id: A0A3B5KI43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNAP-25 family.
messages: synaptosome

31033:kctd10
gene id: 31033:kctd10
uniprot id: A0A3B5KIC2
names: Similarity
messages: Belongs to the BACURD family.

31033:sec61a1
gene id: 31033:sec61a1
uniprot id: H2TCB5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Endoplasmic reticulum membrane
messages: Heterotrimeric complex composed of SEC61-alpha, SEC61-beta and SEC61-gamma.
messages: Membrane
messages: Plays a crucial role in the insertion of secretory and membrane polypeptides into the ER. Required for assembly of membrane and secretory proteins. Tightly associated with membrane-bound ribosomes, either directly or through adapter proteins (By similarity). Plays a role in pronephric kidney tubule development.

31033:LOC101069277
gene id: 31033:LOC101069277
uniprot id: A0A674MHB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Golgi apparatus membrane
messages: Recycling endosome
messages: phagosome
messages: trans-Golgi network membrane

31033:ahcyl1
gene id: 31033:ahcyl1
uniprot id: H2S9L1
uniprot id: H2TA78
names: Similarity
messages: Belongs to the adenosylhomocysteinase family.

31033:slc30a1
gene id: 31033:slc30a1
uniprot id: Q5D1L4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
messages: Membrane

31033:LOC100049641
gene id: 31033:LOC100049641
uniprot id: A1KZS7
uniprot id: H2SG59
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. Flotillin subfamily.
messages: Endosome
messages: Heterooligomeric complex.
messages: Membrane

31033:rbp1
gene id: 31033:rbp1
uniprot id: H2RL96
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

31033:tsfm
gene id: 31033:tsfm
uniprot id: H2S473
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Mitochondrion

31033:sf3b5
gene id: 31033:sf3b5
uniprot id: H2SM01
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SF3B5 family.
messages: Component of the spliceosome B complex.
messages: Nucleus

31033:LOC101068065
gene id: 31033:LOC101068065
uniprot id: H2TV82
names: Similarity
messages: Belongs to the fructosamine kinase family.

31033:LOC101073389
gene id: 31033:LOC101073389
uniprot id: A0A674MC40
names: Subcellular Location Annotation
messages: Membrane

31033:LOC777975
gene id: 31033:LOC777975
uniprot id: Q2NNA8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the noggin family.
messages: Homodimer.
messages: Secreted

31033:LOC101078133
gene id: 31033:LOC101078133
uniprot id: H2S227
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

31033:LOC101079998
gene id: 31033:LOC101079998
uniprot id: A0A3B5K891
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

31033:sub1
gene id: 31033:sub1
uniprot id: A0A674MYM9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transcriptional coactivator PC4 family.
messages: General coactivator that functions cooperatively with TAFs and mediates functional interactions between upstream activators and the general transcriptional machinery. May be involved in stabilizing the multiprotein transcription complex. Binds single-stranded DNA. Also binds, in vitro, non-specifically to double-stranded DNA (ds DNA).
messages: Nucleus

31033:LOC445926
gene id: 31033:LOC445926
uniprot id: P61133
names: Similarity
messages: Belongs to the glycosyl hydrolase 23 family.

31033:psma3
gene id: 31033:psma3
uniprot id: H2T892
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.

31033:tm9sf1
gene id: 31033:tm9sf1
uniprot id: H2U5Y5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family.
messages: Membrane

31033:st8sia1
gene id: 31033:st8sia1
uniprot id: Q6KC14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

31033:pdc
gene id: 31033:pdc
uniprot id: H2SBF7
names: Similarity
messages: Belongs to the phosducin family.

31033:arl4c
gene id: 31033:arl4c
uniprot id: H2S481
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.

31033:LOC101062625
gene id: 31033:LOC101062625
uniprot id: H2TKT1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the somatostatin family.
messages: Secreted
messages: Somatostatin inhibits the release of somatotropin.

31033:psmd7
gene id: 31033:psmd7
uniprot id: A0A3B5KP29
names: Similarity
messages: Belongs to the peptidase M67A family.

31033:tom1
gene id: 31033:tom1
uniprot id: H2SV93
names: Similarity
messages: Belongs to the TOM1 family.

31033:mri1
gene id: 31033:mri1
uniprot id: H2TSE3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).
messages: Cytoplasm
messages: Nucleus

31033:il-2
gene id: 31033:il-2
uniprot id: Q59A92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-15/IL-21 family.
messages: Secreted

31033:LOC101078326
gene id: 31033:LOC101078326
uniprot id: A0A674N412
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: May be involved in podosome and invadosome formation.
messages: invadopodium
messages: podosome

31033:LOC101069338
gene id: 31033:LOC101069338
uniprot id: H2SLN8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the diacylglycerol acyltransferase family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

31033:tent5c
gene id: 31033:tent5c
uniprot id: A0A674MS26
names: Similarity
messages: Belongs to the TENT family.

31033:pah
gene id: 31033:pah
uniprot id: A0A674NY98
uniprot id: Q6IVY7
names: Similarity
messages: Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.

31033:lrp12
gene id: 31033:lrp12
uniprot id: A0A674MKQ5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

31033:paqr5
gene id: 31033:paqr5
uniprot id: H2V194
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

31033:igf1
gene id: 31033:igf1
uniprot id: B6F213
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the insulin family.
messages: Secreted

31033:mtmr11
gene id: 31033:mtmr11
uniprot id: A0A674MM04
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.

31033:znf706
gene id: 31033:znf706
uniprot id: H2TZU1
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

31033:LOC101069210
gene id: 31033:LOC101069210
uniprot id: A0A3B5K7B1
names: Similarity
messages: Belongs to the CD225/Dispanin family.

31033:kcnc1
gene id: 31033:kcnc1
uniprot id: H2U8E7
names: Subcellular Location Annotation
messages: Membrane

31033:actc1
gene id: 31033:actc1
uniprot id: H2UI49
names: Similarity
messages: Belongs to the actin family.

31033:LOC101077130
gene id: 31033:LOC101077130
uniprot id: H2UWP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Membrane

31033:apoA-IV3
gene id: 31033:apoA-IV3
uniprot id: Q5KSU2
names: Similarity
messages: Belongs to the apolipoprotein A1/A4/E family.

31033:lpgat1
gene id: 31033:lpgat1
uniprot id: A0A674NKV1
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

31033:pus10
gene id: 31033:pus10
uniprot id: H2S1W0
names: Similarity
messages: Belongs to the pseudouridine synthase Pus10 family.

31033:bmp2
gene id: 31033:bmp2
uniprot id: Q804S3
names: Similarity
messages: Belongs to the TGF-beta family.

31033:lrrc8c
gene id: 31033:lrrc8c
uniprot id: H2U6A1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LRRC8 family.
messages: Cell membrane
messages: Membrane

31033:cpsf4
gene id: 31033:cpsf4
uniprot id: A0A674P853
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CPSF4/YTH1 family.
messages: Component of the cleavage and polyadenylation specificity factor (CPSF) complex that play a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. CPSF4 binds RNA polymers with a preference for poly(U).
messages: Component of the cleavage and polyadenylation specificity factor (CPSF) complex.
messages: Nucleus

31033:LOC101063787
gene id: 31033:LOC101063787
uniprot id: H2T742
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for thyrotropin-releasing hormone (TRH). Upon ligand binding, this G-protein-coupled receptor triggers activation of the phosphatidylinositol (IP3)-calcium-protein kinase C (PKC) pathway.

31033:LOC101066888
gene id: 31033:LOC101066888
uniprot id: A0A674MUG9
uniprot id: A0A674PD95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COE family.
messages: Nucleus

31033:dlx3
gene id: 31033:dlx3
uniprot id: H2UZF1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the distal-less homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

31033:mmachc
gene id: 31033:mmachc
uniprot id: H2VDC2
names: Similarity
messages: Belongs to the MMACHC family.

31033:myf6
gene id: 31033:myf6
uniprot id: Q6SYV5
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Efficient DNA binding requires dimerization with another bHLH protein.
messages: Involved in muscle differentiation (myogenic factor). Induces fibroblasts to differentiate into myoblasts. Probable sequence specific DNA-binding protein (By similarity).
messages: Nucleus

31033:LOC101066739
gene id: 31033:LOC101066739
uniprot id: H2SQN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

31033:crcp
gene id: 31033:crcp
uniprot id: A0A3B5K3S7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPC9 RNA polymerase subunit family.
messages: Nucleus

31033:LOC101063127
gene id: 31033:LOC101063127
uniprot id: H2UEH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the carnitine/choline acetyltransferase family.
messages: Membrane
messages: Mitochondrion outer membrane

31033:cavin2
gene id: 31033:cavin2
uniprot id: H2S518
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAVIN family.
messages: caveola

31033:czib
gene id: 31033:czib
uniprot id: H2U613
names: Similarity
messages: Belongs to the UPF0587 family.

31033:tmem47
gene id: 31033:tmem47
uniprot id: H2V7X2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM47 family.
messages: Membrane

31033:cnih4
gene id: 31033:cnih4
uniprot id: H2T280
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cornichon family.
messages: Membrane

31033:LOC101061685
gene id: 31033:LOC101061685
uniprot id: H2SXZ9
names: Similarity
messages: Belongs to the small GTPase superfamily. Rab family.

31033:tmem39b
gene id: 31033:tmem39b
uniprot id: H2U1D9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM39 family.
messages: Membrane

31033:ramp2
gene id: 31033:ramp2
uniprot id: A0A3B5KWN7
names: Similarity
messages: Belongs to the RAMP family.

31033:rae1
gene id: 31033:rae1
uniprot id: H2TT72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat rae1 family.
messages: spindle pole

31033:LOC101076887
gene id: 31033:LOC101076887
uniprot id: H2SXG7
names: Similarity
messages: Belongs to the ATP:guanido phosphotransferase family.

31033:eya3
gene id: 31033:eya3
uniprot id: H2TXZ7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAD-like hydrolase superfamily. EYA family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nucleus

31033:utp6
gene id: 31033:utp6
uniprot id: H2U0C2
names: Similarity
messages: Belongs to the UTP6 family.

31033:scn3b
gene id: 31033:scn3b
uniprot id: A0A674MGK7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium channel auxiliary subunit SCN3B (TC 8.A.17) family.
messages: Membrane
messages: Modulates channel gating kinetics. Causes unique persistent sodium currents. Inactivates the sodium channel opening more slowly than the subunit beta-1. Its association with NFASC may target the sodium channels to the nodes of Ranvier of developing axons and retain these channels at the nodes in mature myelinated axons.

31033:LOC105417639
gene id: 31033:LOC105417639
uniprot id: A0A3B5K3E0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptogyrin family.
messages: Membrane

31033:mfsd5
gene id: 31033:mfsd5
uniprot id: Q1KKV8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily.
messages: Cell membrane
messages: Mediates high-affinity intracellular uptake of the rare oligo-element molybdenum.

31033:arpc5
gene id: 31033:arpc5
uniprot id: A0A674MHW7
names: Function
names: Similarity
messages: Belongs to the ARPC5 family.
messages: Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development.

31033:med25
gene id: 31033:med25
uniprot id: H2SPY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 25 family.
messages: Nucleus

31033:LOC101073747
gene id: 31033:LOC101073747
uniprot id: A0A674MVC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

31033:hpx
gene id: 31033:hpx
uniprot id: Q75UL9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the hemopexin family.
messages: Binds heme and transports it to the liver for breakdown and iron recovery, after which the free hemopexin returns to the circulation.
messages: Secreted

31033:lhx4
gene id: 31033:lhx4
uniprot id: H2TLV5
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

31033:guk1
gene id: 31033:guk1
uniprot id: A0A3B5KFA7
names: Similarity
messages: Belongs to the guanylate kinase family.

31033:LOC101073072
gene id: 31033:LOC101073072
uniprot id: A0A3B5KJI2
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

31033:LOC101074951
gene id: 31033:LOC101074951
uniprot id: Q801F2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

31033:LOC101063986
gene id: 31033:LOC101063986
uniprot id: A0A674MQR5
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

31033:LOC101072652
gene id: 31033:LOC101072652
uniprot id: A0A3B5KDN7
names: Subcellular Location Annotation
messages: Nucleus

31033:LOC101077202
gene id: 31033:LOC101077202
uniprot id: H2UU73
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

31033:rnt3
gene id: 31033:rnt3
uniprot id: Q4G5X3
names: Caution
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

31033:insm1
gene id: 31033:insm1
uniprot id: A0A3B5K3B2
names: Subcellular Location Annotation
messages: Nucleus

31033:LOC101078482
gene id: 31033:LOC101078482
uniprot id: A0A674MQP9
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

31033:LOC101069360
gene id: 31033:LOC101069360
uniprot id: A0A3B5JYS8
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.

31033:LOC101062032
gene id: 31033:LOC101062032
uniprot id: A0A674MGR7
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

31033:LOC101080194
gene id: 31033:LOC101080194
uniprot id: A0A3B5KMP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Ras family.
messages: Endosome membrane
messages: Recycling endosome membrane

31033:LOC101063560
gene id: 31033:LOC101063560
uniprot id: A0A674MPH9
names: Similarity
messages: Belongs to the RASGRP family.

31033:dpp3
gene id: 31033:dpp3
uniprot id: H2TEX3
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M49 family.
messages: Binds 1 zinc ion per subunit.

31033:npr3
gene id: 31033:npr3
uniprot id: H2UDQ0
names: Subcellular Location Annotation
messages: Membrane

31033:cacng1
gene id: 31033:cacng1
uniprot id: H2RN58
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
messages: Component of a calcium channel complex consisting of a pore-forming alpha subunit (CACNA1S) and the ancillary subunits CACNB1 or CACNB2, CACNG1 and CACNA2D1. The channel complex contains alpha, beta, gamma and delta subunits in a 1:1:1:1 ratio, i.e. it contains either CACNB1 or CACNB2.
messages: Membrane
messages: Regulatory subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents in skeletal muscle. Regulates channel inactivation kinetics.
messages: sarcolemma

31033:tram1
gene id: 31033:tram1
uniprot id: A0A674P126
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAM family.
messages: Membrane

31033:rpn1
gene id: 31033:rpn1
uniprot id: H2UDT7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OST1 family.
messages: Component of the oligosaccharyltransferase (OST) complex.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.

31033:LOC101062799
gene id: 31033:LOC101062799
uniprot id: H2TGW5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family. Bicoid subfamily.
messages: Nucleus
messages: Plays a critical role in eye formation by regulating the initial specification of retinal cells and/or their subsequent proliferation.
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

31033:six4
gene id: 31033:six4
uniprot id: H2TQP7
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

31033:cldn29a
gene id: 31033:cldn29a
uniprot id: Q6E5R5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

31033:med8
gene id: 31033:med8
uniprot id: H2V005
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 8 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. May play a role as a target recruitment subunit in E3 ubiquitin-protein ligase complexes and thus in ubiquitination and subsequent proteasomal degradation of target proteins.
messages: Component of the Mediator complex.
messages: Nucleus

31033:edem1
gene id: 31033:edem1
uniprot id: H2TV43
names: Similarity
messages: Belongs to the glycosyl hydrolase 47 family.

31033:cfap299
gene id: 31033:cfap299
uniprot id: A0A3B5KC60
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: May be involved in spermatogenesis.
messages: Nucleus

31033:il8
gene id: 31033:il8
uniprot id: Q6F4N2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the intercrine alpha (chemokine CxC) family.
messages: Homodimer.
messages: Secreted

31033:LOC101072457
gene id: 31033:LOC101072457
uniprot id: A0A3B5JVF5
names: Similarity
messages: Belongs to the GST superfamily. Alpha family.

31033:phox2b
gene id: 31033:phox2b
uniprot id: H2T173
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

31033:LOC101079261
gene id: 31033:LOC101079261
uniprot id: H2SBQ4
names: Similarity
messages: Belongs to the adaptor complexes large subunit family.

31033:LOC101071216
gene id: 31033:LOC101071216
uniprot id: H2TU30
names: Similarity
messages: Belongs to the stathmin family.

31033:LOC101066220
gene id: 31033:LOC101066220
uniprot id: A0A3B5K127
names: Subcellular Location Annotation
messages: Mitochondrion intermembrane space

31033:smim7
gene id: 31033:smim7
uniprot id: A0A3B5JY56
names: Similarity
messages: Belongs to the SMIM7 family.

31033:LOC101067566
gene id: 31033:LOC101067566
uniprot id: A0A674MFK4
uniprot id: A0A674NWU8
names: Similarity
messages: Belongs to the phosphatase 2A regulatory subunit B family.

31033:LOC101061481
gene id: 31033:LOC101061481
uniprot id: Q1KKY4
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

31033:pole
gene id: 31033:pole
uniprot id: A0A3B5KBV2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-B family.
messages: DNA polymerase II participates in chromosomal DNA replication.
messages: Nucleus

31033:pou2f1
gene id: 31033:pou2f1
uniprot id: A0A674PH32
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family. Class-2 subfamily.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

31033:tapt1
gene id: 31033:tapt1
uniprot id: H2USE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAPT1 family.
messages: Membrane

31033:mcm6
gene id: 31033:mcm6
uniprot id: A0A674PKG1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.
messages: Belongs to the MCM family.
messages: Component of the MCM2-7 complex.
messages: Nucleus

31033:fut11
gene id: 31033:fut11
uniprot id: Q70AG8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 10 family.
messages: Golgi stack membrane
messages: Probable fucosyltransferase.

31033:LOC101073693
gene id: 31033:LOC101073693
uniprot id: H2URJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR3 subfamily.
messages: Nucleus

31033:LOC101075901
gene id: 31033:LOC101075901
uniprot id: H2V214
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GOT1 family.
messages: Golgi apparatus membrane
messages: May be involved in fusion of ER-derived transport vesicles with the Golgi complex.
messages: Membrane

31033:surf4
gene id: 31033:surf4
uniprot id: O57590
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF4 family.
messages: Endoplasmic reticulum cargo receptor that mediates the export of lipoproteins by recruiting cargos into COPII vesicles to facilitate their secretion. Acts as a cargo receptor for lipoproteins bearing both APOB and APOA1, thereby regulating lipoprotein delivery and the maintenance of lipid homeostasis.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Golgi apparatus membrane
messages: The di-lysine motif confers endoplasmic reticulum localization for type I membrane proteins.

31033:LOC101068913
gene id: 31033:LOC101068913
uniprot id: H2SDH2
names: Similarity
messages: Belongs to the TGF-beta family.

31033:panx2
gene id: 31033:panx2
uniprot id: A0A3B5K011
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pannexin family.
messages: Cell membrane
messages: Membrane
messages: Structural component of the gap junctions and the hemichannels.
messages: gap junction

31033:LOC101078762
gene id: 31033:LOC101078762
uniprot id: H2UJR9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphatidyl serine synthase family.
messages: Catalyzes a base-exchange reaction in which the polar head group of phosphatidylethanolamine (PE) is replaced by L-serine.
messages: Endoplasmic reticulum membrane
messages: Membrane

31033:med6
gene id: 31033:med6
uniprot id: H2TYG0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 6 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

31033:LOC101068320
gene id: 31033:LOC101068320
uniprot id: H2S9I2
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

31033:sptbn1
gene id: 31033:sptbn1
uniprot id: H2U143
names: Similarity
messages: Belongs to the spectrin family.

31033:elac1
gene id: 31033:elac1
uniprot id: H2U8I3
names: Subunit
messages: Homodimer.

31033:LOC101080150
gene id: 31033:LOC101080150
uniprot id: A0A674MXC6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class III subfamily.
messages: Induces bone formation in conjunction with TGF-beta-1 or TGF-beta-2.
messages: extracellular matrix

31033:LOC101066180
gene id: 31033:LOC101066180
uniprot id: A0A674MYD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the grh/CP2 family. CP2 subfamily.
messages: Nucleus

31033:bmp7
gene id: 31033:bmp7
uniprot id: A0A674MBF0
names: Similarity
messages: Belongs to the TGF-beta family.

31033:LOC101071166
gene id: 31033:LOC101071166
uniprot id: A0A674NY49
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

31033:LOC101065984
gene id: 31033:LOC101065984
uniprot id: H2TT21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

31033:olfm1
gene id: 31033:olfm1
uniprot id: A0A674MJR7
uniprot id: H2VEA2
names: Subcellular Location Annotation
messages: Secreted
messages: Synapse

31033:foxn2
gene id: 31033:foxn2
uniprot id: H2UDM3
names: Subcellular Location Annotation
messages: Nucleus

31033:LOC101063713
gene id: 31033:LOC101063713
uniprot id: A0A3B5K100
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FUN14 family.
messages: Mitochondrion outer membrane

31033:KEF89 p12
gene id: 31033:KEF89_p12
uniprot id: Q8HCW4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 2 family.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.
messages: Membrane
messages: Mitochondrion inner membrane

31033:LOC101064909
gene id: 31033:LOC101064909
uniprot id: H2RJG2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
messages: Membrane
messages: Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state.

31033:atg12
gene id: 31033:atg12
uniprot id: A0A674P1N5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ATG12 family.
messages: Forms a conjugate with ATG5.
messages: Ubiquitin-like protein involved in autophagic vesicle formation.

31033:mct4a
gene id: 31033:mct4a
uniprot id: H1ABV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.
messages: Membrane

31033:LOC101065096
gene id: 31033:LOC101065096
uniprot id: A0A3B5KAK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

31033:polr1c
gene id: 31033:polr1c
uniprot id: A0A674NCA1
names: Similarity
messages: Belongs to the archaeal Rpo3/eukaryotic RPB3 RNA polymerase subunit family.

31033:taf7l
gene id: 31033:taf7l
uniprot id: A0A674MN36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF7 family.
messages: Nucleus

31033:LOC101062889
gene id: 31033:LOC101062889
uniprot id: H2SSV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family. BCS1 subfamily.
messages: Membrane
messages: Mitochondrion inner membrane

31033:LOC101061169
gene id: 31033:LOC101061169
uniprot id: H2TF22
names: Similarity
messages: Belongs to the glycosyl hydrolase 35 family.

31033:slc41a2
gene id: 31033:slc41a2
uniprot id: A0A6D2WN87
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Membrane

31033:slc35a3
gene id: 31033:slc35a3
uniprot id: H2V8V2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide-sugar transporter family. SLC35A subfamily.
messages: Membrane

31033:arl5a
gene id: 31033:arl5a
uniprot id: H2UK67
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.

31033:prkn
gene id: 31033:prkn
uniprot id: Q5J4W3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RBR family. Parkin subfamily.
messages: Forms an E3 ubiquitin ligase complex.
messages: Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins.
messages: Mitochondrion
messages: cytosol

31033:LOC101076657
gene id: 31033:LOC101076657
uniprot id: H2SWH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NPY family.
messages: Secreted

31033:LOC101065380
gene id: 31033:LOC101065380
uniprot id: Q6E5T5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

31033:hepacam2
gene id: 31033:hepacam2
uniprot id: H2UP93
names: Subcellular Location Annotation
messages: Membrane

31033:per2
gene id: 31033:per2
uniprot id: H2SWF5
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

31033:LOC101078429
gene id: 31033:LOC101078429
uniprot id: H2RJ92
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERGIC family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Golgi apparatus membrane
messages: Plays a role in transport between endoplasmic reticulum and Golgi.

31033:exoc5
gene id: 31033:exoc5
uniprot id: A0A3B5KIV1
names: Function
names: Similarity
messages: Belongs to the SEC10 family.
messages: Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.

31033:edem3
gene id: 31033:edem3
uniprot id: A0A674NGB8
uniprot id: H2V8H1
names: Similarity
messages: Belongs to the glycosyl hydrolase 47 family.

31033:LOC105416191
gene id: 31033:LOC105416191
uniprot id: H2T673
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone H1/H5 family.
messages: Nucleus

31033:LOC101067404
gene id: 31033:LOC101067404
uniprot id: H2S5F8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptophysin/synaptobrevin family.
messages: Membrane

31033:nfe2l1
gene id: 31033:nfe2l1
uniprot id: H2U273
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. CNC subfamily.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Nucleus

31033:LOC101066898
gene id: 31033:LOC101066898
uniprot id: A0A674P4E9
names: Subcellular Location Annotation
messages: Mitochondrion intermembrane space

31033:LOC101066594
gene id: 31033:LOC101066594
uniprot id: A0A3B5KGW9
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

31033:mmp23b
gene id: 31033:mmp23b
uniprot id: H2SQ54
names: Caution
names: Similarity
messages: Belongs to the peptidase M10A family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

31033:il1b
gene id: 31033:il1b
uniprot id: H2UVE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-1 family.
messages: Lysosome
messages: cytosol
messages: extracellular exosome

31033:LOC101066563
gene id: 31033:LOC101066563
uniprot id: A0A3B5KG61
names: Activity Regulation
names: Similarity
messages: Activated by threonine and tyrosine phosphorylation.
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.

31033:LOC101071011
gene id: 31033:LOC101071011
uniprot id: H2SB21
names: Similarity
messages: Belongs to the LSM14 family.

31033:rpl32
gene id: 31033:rpl32
uniprot id: A0A3B5KRF6
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL32 family.

31033:LOC101072674
gene id: 31033:LOC101072674
uniprot id: H2V3T6
names: Similarity
messages: Belongs to the TGF-beta family.

31033:trappc6b
gene id: 31033:trappc6b
uniprot id: H2SS24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAPP small subunits family. BET3 subfamily.
messages: Endoplasmic reticulum
messages: cis-Golgi network

31033:slc30a4
gene id: 31033:slc30a4
uniprot id: A0A3B5K5B9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
messages: Membrane

31033:LOC101063036
gene id: 31033:LOC101063036
uniprot id: A0A3B5K3H6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase VIII family.
messages: Membrane
messages: Mitochondrion inner membrane

31033:LOC101079583
gene id: 31033:LOC101079583
uniprot id: A0A674MIU8
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

31033:npy2r
gene id: 31033:npy2r
uniprot id: A7XY83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

31033:sec22c
gene id: 31033:sec22c
uniprot id: H2V792
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Endoplasmic reticulum membrane
messages: May be involved in vesicle transport between the ER and the Golgi complex.
messages: Membrane

31033:ackr3
gene id: 31033:ackr3
uniprot id: H2TRG5
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

31033:uck1
gene id: 31033:uck1
uniprot id: H2VCE9
names: Similarity
messages: Belongs to the uridine kinase family.

31033:LOC101062285
gene id: 31033:LOC101062285
uniprot id: A0A674P105
names: Similarity
messages: Belongs to the carotenoid oxygenase family.

31033:chmp2a
gene id: 31033:chmp2a
uniprot id: H2TY84
names: Similarity
messages: Belongs to the SNF7 family.

31033:LOC105416482
gene id: 31033:LOC105416482
uniprot id: A0A3B5KG64
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein phosphatase inhibitor 1 family.
messages: Cytoplasm
messages: Inhibitor of protein-phosphatase 1.

31033:sat1
gene id: 31033:sat1
uniprot id: F7VJJ3
names: Similarity
names: Subunit
messages: Belongs to the acetyltransferase family.
messages: Homodimer.

31033:LOC101067009
gene id: 31033:LOC101067009
uniprot id: A0A3B5K5R5
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

31033:LOC101067444
gene id: 31033:LOC101067444
uniprot id: H2SNX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM54 family.
messages: Membrane

31033:ext2
gene id: 31033:ext2
uniprot id: H2V525
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 47 family.
messages: Endoplasmic reticulum membrane

31033:dstyk
gene id: 31033:dstyk
uniprot id: Q4VSN2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Basolateral cell membrane
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
messages: Cell junction
messages: Cell membrane
messages: Cytoplasm
messages: May act as a positive regulator of ERK phosphorylation downstream of fibroblast growth factor-receptor activation. May induce both caspase-dependent apoptosis and caspase-independent cell death. May play a role in the embryonic development.

31033:eif3d
gene id: 31033:eif3d
uniprot id: H2T4N9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit D family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M.
messages: Cytoplasm
messages: The RNA gate region regulates mRNA cap recognition to prevent promiscuous mRNA-binding before assembly of eif3d into the full eukaryotic translation initiation factor 3 (eIF-3) complex.
messages: mRNA cap-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. In the eIF-3 complex, eif3d specifically recognizes and binds the 7-methylguanosine cap of a subset of mRNAs.

31033:hopx
gene id: 31033:hopx
uniprot id: A0A3B5K7Y3
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

31033:rpl9
gene id: 31033:rpl9
uniprot id: H2TEV3
names: Similarity
messages: Belongs to the universal ribosomal protein uL6 family.

31033:npy8br
gene id: 31033:npy8br
uniprot id: A7XY87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

31033:rpe65
gene id: 31033:rpe65
uniprot id: A0A674N730
names: Similarity
messages: Belongs to the carotenoid oxygenase family.

31033:LOC101062393
gene id: 31033:LOC101062393
uniprot id: H2SLN6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Membrane
messages: Retinol dehydrogenase with a clear preference for NADP. Converts all-trans-retinal to all-trans-retinol. May play a role in the regeneration of visual pigment at high light intensity.

31033:LOC101062565
gene id: 31033:LOC101062565
uniprot id: H2T5C5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC29A/ENT transporter (TC 2.A.57) family.
messages: Membrane

31033:chmp1b
gene id: 31033:chmp1b
uniprot id: H2UDT8
names: Similarity
messages: Belongs to the SNF7 family.

31033:LOC105418355
gene id: 31033:LOC105418355
uniprot id: H2SK94
names: Similarity
messages: Belongs to the RGS7BP/RGS9BP family.

31033:alpl
gene id: 31033:alpl
uniprot id: Q8AXY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alkaline phosphatase family.
messages: Cell membrane
messages: Membrane

31033:lin7c
gene id: 31033:lin7c
uniprot id: A0A674NGI0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lin-7 family.
messages: Cell junction
messages: Cell membrane
messages: Membrane
messages: Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells.

31033:LOC101079307
gene id: 31033:LOC101079307
uniprot id: H2V8U4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the akirin family.
messages: Nucleus

31033:aldh6a1
gene id: 31033:aldh6a1
uniprot id: A0A674P718
names: Function
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.
messages: Plays a role in valine and pyrimidine metabolism. Binds fatty acyl-CoA.

31033:pld4
gene id: 31033:pld4
uniprot id: A0A674PIH7
names: Similarity
messages: Belongs to the phospholipase D family.

31033:adamts1
gene id: 31033:adamts1
uniprot id: H2TR39
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

31033:npb
gene id: 31033:npb
uniprot id: H2TX89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neuropeptide B/W family.
messages: Secreted

31033:pno1
gene id: 31033:pno1
uniprot id: H2U3T0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PNO1 family.
messages: nucleolus

31033:psmb3
gene id: 31033:psmb3
uniprot id: A0A3B5KAB3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome complex.
messages: Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
messages: Cytoplasm
messages: Nucleus

31033:odr4
gene id: 31033:odr4
uniprot id: A0A3B5KSD6
names: Function
names: Similarity
messages: Belongs to the ODR-4 family.
messages: May play a role in the trafficking of a subset of G-protein coupled receptors.

31033:atp5mc3
gene id: 31033:atp5mc3
uniprot id: Q1KKT5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Membrane
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. A homomeric c-ring of probably 10 subunits is part of the complex rotary element.
messages: Mitochondrion membrane

31033:echs1
gene id: 31033:echs1
uniprot id: H2UBV2
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

31033:LOC101072058
gene id: 31033:LOC101072058
uniprot id: H2RUY8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H4 family.
messages: Chromosome
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

31033:ikbke
gene id: 31033:ikbke
uniprot id: A0A674NVT1
names: Subcellular Location Annotation
messages: Cytoplasm

31033:KEF89 p06
gene id: 31033:KEF89_p06
uniprot id: Q8HCV8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 3 family.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity of complex I.
messages: Mitochondrion membrane

31033:pcyt1b
gene id: 31033:pcyt1b
uniprot id: A0A674PMD5
names: Function
names: Similarity
messages: Belongs to the cytidylyltransferase family.
messages: Catalyzes the key rate-limiting step in the CDP-choline pathway for phosphatidylcholine biosynthesis.

31033:LOC101065268
gene id: 31033:LOC101065268
uniprot id: A0A3B5KCV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic mitochondrial porin family.
messages: Mitochondrion outer membrane

31033:pemt
gene id: 31033:pemt
uniprot id: H2V443
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class VI-like SAM-binding methyltransferase superfamily. PEMT/PEM2 methyltransferase family.
messages: Catalyzes the three sequential steps of the methylation pathway for the biosynthesis of phosphatidylcholine, a critical and essential component for membrane structure. Uses S-adenosylmethionine (S-adenosyl-L-methionine, SAM or AdoMet) as the methyl group donor for the methylation of phosphatidylethanolamine (1,2-diacyl-sn-glycero-3-phosphoethanolamine, PE) to phosphatidylmonomethylethanolamine (1,2-diacyl-sn-glycero-3-phospho-N-methylethanolamine, PMME), PMME to phosphatidyldimethylethanolamine (1,2-diacyl-sn-glycero-3-phospho-N,N-dimethylethanolamine, PDME), and PDME to phosphatidylcholine (1,2-diacyl-sn-glycero-3-phosphocholine, PC), producing S-adenosyl-L-homocysteine in each step.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Mitochondrion membrane

31033:rpa3
gene id: 31033:rpa3
uniprot id: A0A3B5KKW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the replication factor A protein 3 family.
messages: Nucleus

31033:cldn27b
gene id: 31033:cldn27b
uniprot id: Q6E5Q5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

31033:g6pc
gene id: 31033:g6pc
uniprot id: H2SVW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glucose-6-phosphatase family.
messages: Endoplasmic reticulum membrane

31033:mapre2
gene id: 31033:mapre2
uniprot id: A0A674NAN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAPRE family.
messages: cytoskeleton

31033:dpy19l1
gene id: 31033:dpy19l1
uniprot id: A0A674NIR7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dpy-19 family.
messages: Membrane
messages: Probable C-mannosyltransferase that mediates C-mannosylation of tryptophan residues on target proteins.

31033:LOC101067231
gene id: 31033:LOC101067231
uniprot id: A0A3B5KB47
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.

31033:gosr2
gene id: 31033:gosr2
uniprot id: H2UHM1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GOSR2 family.
messages: Involved in transport of proteins from the cis/medial-Golgi to the trans-Golgi network.
messages: Membrane

31033:LOC101066812
gene id: 31033:LOC101066812
uniprot id: H2RND2
names: Similarity
messages: Belongs to the SLBP family.

31033:hikeshi
gene id: 31033:hikeshi
uniprot id: A0A3B5KJS1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a specific nuclear import carrier for HSP70 proteins following heat-shock stress: acts by mediating the nucleoporin-dependent translocation of ATP-bound HSP70 proteins into the nucleus. HSP70 proteins import is required to protect cells from heat shock damages. Does not translocate ADP-bound HSP70 proteins into the nucleus.
messages: Belongs to the OPI10 family.
messages: Cytoplasm
messages: Forms an asymmetric homodimer; required for binding and nuclear import of HSP70 proteins. Interacts with ATP-bound HSP70 proteins.
messages: Nucleus
messages: cytosol

31033:slc7a11
gene id: 31033:slc7a11
uniprot id: A0A674PDG1
names: Subcellular Location Annotation
messages: Membrane

31033:cxcl13
gene id: 31033:cxcl13
uniprot id: E5RMA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine alpha (chemokine CxC) family.
messages: Secreted

31033:sf3a2
gene id: 31033:sf3a2
uniprot id: H2TDJ6
names: Similarity
messages: Belongs to the SF3A2 family.

31033:LOC101075808
gene id: 31033:LOC101075808
uniprot id: H2TRE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DP1 family.
messages: Membrane

31033:kcnd1
gene id: 31033:kcnd1
uniprot id: H2UBT9
names: Subcellular Location Annotation
messages: Membrane
messages: dendrite

31033:dhrs7
gene id: 31033:dhrs7
uniprot id: H2TN82
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

31033:timm10
gene id: 31033:timm10
uniprot id: H2ULG2
names: Function
messages: Mitochondrial intermembrane chaperone that participates in the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. May also be required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.

31033:plod3
gene id: 31033:plod3
uniprot id: A5A6S2
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane

31033:LOC101065025
gene id: 31033:LOC101065025
uniprot id: H2RIY1
names: Similarity
messages: Belongs to the Luc7 family.

31033:fnbp1l
gene id: 31033:fnbp1l
uniprot id: H2SQN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FNBP1 family.
messages: Cytoplasmic vesicle
messages: Vesicle
messages: cell cortex

31033:polr3b
gene id: 31033:polr3b
uniprot id: H2TAU9
names: Function
names: Similarity
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.

31033:gipc1
gene id: 31033:gipc1
uniprot id: H2U7J7
names: Similarity
messages: Belongs to the GIPC family.

31033:LOC101075972
gene id: 31033:LOC101075972
uniprot id: H2SSW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 47 family.
messages: Endoplasmic reticulum membrane

31033:LOC101074842
gene id: 31033:LOC101074842
uniprot id: H2SCZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. EGF receptor subfamily.
messages: Membrane

31033:LOC101070062
gene id: 31033:LOC101070062
uniprot id: A0A674N4F1
names: Similarity
messages: Belongs to the PICALM/SNAP91 family.

31033:afap1l1
gene id: 31033:afap1l1
uniprot id: H2T112
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: May be involved in podosome and invadosome formation.
messages: invadopodium
messages: podosome

31033:uxs1
gene id: 31033:uxs1
uniprot id: A0A674NEX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.
messages: Golgi stack membrane
messages: Membrane

31033:anapc4
gene id: 31033:anapc4
uniprot id: H2UJE7
names: Function
names: Similarity
messages: Belongs to the APC4 family.
messages: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle.

31033:slc20a2
gene id: 31033:slc20a2
uniprot id: H2V0J3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane
messages: Sodium-phosphate symporter which plays a fundamental housekeeping role in phosphate transport.

31033:LOC101075838
gene id: 31033:LOC101075838
uniprot id: A0A3B5JWV5
names: Similarity
messages: Belongs to the TBP family.

31033:ilf3
gene id: 31033:ilf3
uniprot id: A0A674NY61
uniprot id: A0A674PRN2
uniprot id: H2TSL9
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

31033:mtg2
gene id: 31033:mtg2
uniprot id: H2RTV8
names: Similarity
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.

31033:banp
gene id: 31033:banp
uniprot id: H2SGT5
names: Similarity
messages: Belongs to the BANP/SMAR1 family.

31033:klhl21
gene id: 31033:klhl21
uniprot id: H2TCP1
names: Subcellular Location Annotation
messages: spindle

31033:LOC101073692
gene id: 31033:LOC101073692
uniprot id: A0A674MG17
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Membrane
messages: The small GTPases Rab are key regulators in vesicle trafficking.

31033:LOC101064948
gene id: 31033:LOC101064948
uniprot id: H2SKN0
names: Subcellular Location Annotation
messages: Cytoplasmic vesicle
messages: Vesicle

31033:ccr6
gene id: 31033:ccr6
uniprot id: G5EII2
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

31033:LOC101075237
gene id: 31033:LOC101075237
uniprot id: H2RJS8
names: Subcellular Location Annotation
messages: Membrane

31033:coq9
gene id: 31033:coq9
uniprot id: A0A674NQ27
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COQ9 family.
messages: Lipid-binding protein involved in the biosynthesis of coenzyme Q, also named ubiquinone, an essential lipid-soluble electron transporter for aerobic cellular respiration.
messages: Mitochondrion

31033:LOC101068024
gene id: 31033:LOC101068024
uniprot id: H2S8T6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

31033:LOC101068458
gene id: 31033:LOC101068458
uniprot id: H2UJ44
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular space

31033:LOC101067924
gene id: 31033:LOC101067924
uniprot id: H2UMV3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chondroitin N-acetylgalactosaminyltransferase family.
messages: Golgi stack membrane
messages: Membrane
messages: Transfers N-acetylgalactosamine (GalNAc) from UDP-GalNAc to N-acetylglucosamine-beta-benzyl with a beta-1,4-linkage to form N,N'-diacetyllactosediamine, GalNAc-beta-1,4-GlcNAc structures in N-linked glycans and probably O-linked glycans.

31033:mak16
gene id: 31033:mak16
uniprot id: H2TWV2
names: Similarity
messages: Belongs to the MAK16 family.

31033:ptx3
gene id: 31033:ptx3
uniprot id: A0A674N0X7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

31033:LOC101069232
gene id: 31033:LOC101069232
uniprot id: Q90WS1
names: Function
names: Similarity
messages: Belongs to the type IB topoisomerase family.
messages: Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus removing DNA supercoils. Finally, in the religation step, the DNA 5'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

31033:ercc3
gene id: 31033:ercc3
uniprot id: A0A3B5K7N7
names: Similarity
messages: Belongs to the helicase family. RAD25/XPB subfamily.

31033:mtm1
gene id: 31033:mtm1
uniprot id: A0A3B5KP70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.
messages: Cell membrane
messages: Late endosome
messages: filopodium
messages: ruffle
messages: sarcomere

31033:wnt2
gene id: 31033:wnt2
uniprot id: Q8UW39
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

31033:LOC101062207
gene id: 31033:LOC101062207
uniprot id: A0A3B5JZD7
uniprot id: A0A3B5KGK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the shaker potassium channel beta subunit family.
messages: Cell membrane
messages: Cytoplasm
messages: Membrane

31033:LOC101066252
gene id: 31033:LOC101066252
uniprot id: H2UUF1
names: Similarity
messages: Belongs to the DIP2 family.

31033:terf1
gene id: 31033:terf1
uniprot id: H2U488
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Binds the telomeric double-stranded 5'-TTAGGG-3' repeat.
messages: Homodimer.
messages: Nucleus

31033:tmod1
gene id: 31033:tmod1
uniprot id: A0A674P7X7
names: Subcellular Location Annotation
messages: cytoskeleton

31033:LOC101065330
gene id: 31033:LOC101065330
uniprot id: A0A674NSZ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the stanniocalcin family.
messages: Homodimer; disulfide-linked.
messages: Its primary function is the prevention of hypercalcemia. Upon release into the circulation, it lowers calcium transport by the gills, thereby reducing its rate of influx from the environment into the extracellular compartment. STC also stimulates phosphate reabsorption by renal proximal tubules. The consequence of this action is increased levels of plasma phosphate, which combines with excess calcium and promotes its disposal into bone and scales.

31033:LOC101075139
gene id: 31033:LOC101075139
uniprot id: A0A3B5KT25
names: Similarity
messages: Belongs to the nucleosome assembly protein (NAP) family.

31033:LOC101077396
gene id: 31033:LOC101077396
uniprot id: A0A674MDJ2
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

31033:LOC101071498
gene id: 31033:LOC101071498
uniprot id: O57655
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the rate-limiting step of the oxidative pentose-phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis.

31033:LOC101078763
gene id: 31033:LOC101078763
uniprot id: H2T7K1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIC subfamily.
messages: Cell membrane

31033:pfcyp19a
gene id: 31033:pfcyp19a
uniprot id: A9EE90
names: Similarity
messages: Belongs to the cytochrome P450 family.

31033:pparg
gene id: 31033:pparg
uniprot id: A4PE14
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Cytoplasm
messages: Heterodimer with other nuclear receptors.
messages: Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. May play a role in the regulation of circadian rhythm.
messages: Nucleus

31033:pomgnt2
gene id: 31033:pomgnt2
uniprot id: I6L6Z5
uniprot id: Q5NDE4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 61 family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: O-linked mannose beta-1,4-N-acetylglucosaminyltransferase that transfers UDP-N-acetyl-D-glucosamine to the 4-position of the mannose to generate N-acetyl-D-glucosamine-beta-1,4-O-D-mannosylprotein. Involved in the biosynthesis of the phosphorylated O-mannosyl trisaccharide (N-acetylgalactosamine-beta-3-N-acetylglucosamine-beta-4-(phosphate-6-)mannose), a carbohydrate structure present in alpha-dystroglycan (DAG1), which is required for binding laminin G-like domain-containing extracellular proteins with high affinity (By similarity).

31033:rock2
gene id: 31033:rock2
uniprot id: A0A674MUZ9
uniprot id: H2TR74
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by RHOA binding. Inhibited by Y-27632.
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.
messages: Cell membrane
messages: Homodimer.
messages: Protein kinase which is a key regulator of actin cytoskeleton and cell polarity.
messages: centrosome

31033:mc2r
gene id: 31033:mc2r
uniprot id: Q7ZSX7
names: Subcellular Location Annotation
names: Subunit
messages: Cell membrane
messages: Interacts with MRAP; increasing ligand-sensitivity and generation of cAMP. Interacts with MRAP2; competing with MRAP for binding to MC2R and impairing the binding of corticotropin (ACTH).
messages: Membrane

31033:rer1
gene id: 31033:rer1
uniprot id: A0A674N3A2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RER1 family.
messages: Involved in the retrieval of endoplasmic reticulum membrane proteins from the early Golgi compartment.
messages: Membrane

31033:ildr2
gene id: 31033:ildr2
uniprot id: H2U5H7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. LISCH7 family.
messages: Membrane
messages: tight junction

31033:set
gene id: 31033:set
uniprot id: A0A674MQH5
names: Similarity
messages: Belongs to the nucleosome assembly protein (NAP) family.

31033:atp6v1e1
gene id: 31033:atp6v1e1
uniprot id: H2S2M4
names: Similarity
messages: Belongs to the V-ATPase E subunit family.

31033:mpv17l2
gene id: 31033:mpv17l2
uniprot id: H2SR57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxisomal membrane protein PXMP2/4 family.
messages: Membrane

31033:atg4c
gene id: 31033:atg4c
uniprot id: H2VDW1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C54 family.
messages: Cysteine protease that plays a key role in autophagy by mediating both proteolytic activation and delipidation of ATG8 family proteins.
messages: Cytoplasm

31033:acvr1b
gene id: 31033:acvr1b
uniprot id: A0A3B5K7U3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane

31033:LOC101080220
gene id: 31033:LOC101080220
uniprot id: H2TS71
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cyclin family. Cyclin AB subfamily.
messages: Belongs to the cyclin family. Cyclin D subfamily.
messages: Cytoplasm
messages: Essential for the control of the cell cycle at the G2/M (mitosis) transition.
messages: Interacts with the CDK1 protein kinase to form a serine/threonine kinase holoenzyme complex also known as maturation promoting factor (MPF). The cyclin subunit imparts substrate specificity to the complex.
messages: Nucleus

31033:LOC101065833
gene id: 31033:LOC101065833
uniprot id: A0A3B5K7L3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heparin-binding growth factors family.
messages: Secreted

31033:LOC101070754
gene id: 31033:LOC101070754
uniprot id: H2S4P0
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

31033:acss2
gene id: 31033:acss2
uniprot id: H2TZK4
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

31033:tmem50b
gene id: 31033:tmem50b
uniprot id: H2RSU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0220 family.
messages: Membrane

31033:ntn1
gene id: 31033:ntn1
uniprot id: H2U9Y6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

31033:coq3
gene id: 31033:coq3
uniprot id: H2RKA9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family.
messages: Component of a multi-subunit COQ enzyme complex, composed of at least COQ3, COQ4, COQ5, COQ6, COQ7 and COQ9.
messages: Mitochondrion inner membrane
messages: O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.

31033:smc4
gene id: 31033:smc4
uniprot id: Q8AW94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMC family. SMC4 subfamily.
messages: Chromosome
messages: Nucleus

31033:LOC101076940
gene id: 31033:LOC101076940
uniprot id: H2RUE5
names: Similarity
names: Subunit
messages: Belongs to the group II decarboxylase family.
messages: Homodimer.

31033:LOC101067094
gene id: 31033:LOC101067094
uniprot id: H2UFA1
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

31033:slitrk6
gene id: 31033:slitrk6
uniprot id: H2UGU3
names: Similarity
messages: Belongs to the SLITRK family.

31033:LOC101070200
gene id: 31033:LOC101070200
uniprot id: A0A3B5KGG5
names: Similarity
messages: Belongs to the FAM131 family.

31033:tmem33
gene id: 31033:tmem33
uniprot id: A0A674PAH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PER33/POM33 family.
messages: Membrane

31033:rp2
gene id: 31033:rp2
uniprot id: H2TSJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a GTPase-activating protein (GAP) for tubulin in concert with tubulin-specific chaperone C, but does not enhance tubulin heterodimerization.
messages: Belongs to the TBCC family.
messages: Cell membrane
messages: Membrane

31033:gle1
gene id: 31033:gle1
uniprot id: H2SVR6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GLE1 family.
messages: Required for the export of mRNAs containing poly(A) tails from the nucleus into the cytoplasm. May be involved in the terminal step of the mRNA transport through the nuclear pore complex (NPC).
messages: nuclear pore complex

31033:sec23a
gene id: 31033:sec23a
uniprot id: H2SRP3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC23/SEC24 family. SEC23 subfamily.
messages: COPII-coated vesicle membrane
messages: Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: cytosol

31033:LOC101063559
gene id: 31033:LOC101063559
uniprot id: A0A3B5K4R2
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

31033:ufl1
gene id: 31033:ufl1
uniprot id: A0A674NM83
names: Similarity
messages: Belongs to the UFL1 family.

31033:p3h2
gene id: 31033:p3h2
uniprot id: H2V7Q6
names: Similarity
messages: Belongs to the leprecan family.

31033:mrpl58
gene id: 31033:mrpl58
uniprot id: A0A674PRV8
names: Subcellular Location Annotation
messages: Mitochondrion

31033:rbp4
gene id: 31033:rbp4
uniprot id: H2TR59
names: Similarity
messages: Belongs to the calycin superfamily. Lipocalin family.

31033:LOC101061713
gene id: 31033:LOC101061713
uniprot id: A0A3B5K600
uniprot id: A0A674NHP4
uniprot id: H2TWX6
uniprot id: H2TWX9
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.

31033:LOC101078548
gene id: 31033:LOC101078548
uniprot id: H2RKF3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.
messages: Cytoplasm
messages: Responds to activation by environmental stress and pro-inflammatory cytokines by phosphorylating a number of transcription factors, and thus regulates transcriptional activity.

31033:dlk1
gene id: 31033:dlk1
uniprot id: H2TEW9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

31033:sar1b
gene id: 31033:sar1b
uniprot id: A0A3B5KN34
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.
messages: Belongs to the small GTPase superfamily. SAR1 family.

31033:bud23
gene id: 31033:bud23
uniprot id: H2T7J8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. BUD23/WBSCR22 family.
messages: Cytoplasm
messages: Nucleus

31033:LOC101077924
gene id: 31033:LOC101077924
uniprot id: H2SLZ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GnRH family.
messages: Secreted
messages: Stimulates the secretion of gonadotropins.

31033:LOC101077055
gene id: 31033:LOC101077055
uniprot id: H2VBS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

31033:LOC101079972
gene id: 31033:LOC101079972
uniprot id: H2SUU6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

31033:rps17
gene id: 31033:rps17
uniprot id: H2UH56
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS17 family.

31033:ccn4
gene id: 31033:ccn4
uniprot id: H2TQJ3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCN family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

31033:LOC101073733
gene id: 31033:LOC101073733
uniprot id: A0A674MI79
uniprot id: A0A674NKU6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rho family. CDC42 subfamily.
messages: Cell membrane
messages: Membrane
messages: Midbody
messages: Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state.

31033:pcsk2
gene id: 31033:pcsk2
uniprot id: A0A674P0J8
names: Similarity
messages: Belongs to the peptidase S8 family.

31033:ubac1
gene id: 31033:ubac1
uniprot id: H2UZZ7
names: Subcellular Location Annotation
messages: Cytoplasm

31033:LOC101063580
gene id: 31033:LOC101063580
uniprot id: H2TZR9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurexin family.
messages: Belongs to the syndecan proteoglycan family.
messages: Cell surface proteoglycan.
messages: Membrane

31033:ruvbl1
gene id: 31033:ruvbl1
uniprot id: H2TNQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RuvB family.
messages: Dynein axonemal particle
messages: Nucleus
messages: Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding.

31033:tacr3
gene id: 31033:tacr3
uniprot id: A0A6D2X5R4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

31033:rbm17
gene id: 31033:rbm17
uniprot id: A0A3B5KPA8
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Associates with the spliceosome.
messages: Nucleus
messages: Splice factor that binds to the single-stranded 3'AG at the exon/intron border and promotes its utilization in the second catalytic step. Involved in the regulation of alternative splicing and the utilization of cryptic splice sites.

31033:ywhaq
gene id: 31033:ywhaq
uniprot id: H2UDY6
names: Similarity
names: Subunit
messages: Belongs to the 14-3-3 family.
messages: Homodimer, and heterodimer with other family members.

31033:LOC101079587
gene id: 31033:LOC101079587
uniprot id: A0A3B5KI73
names: Caution
names: Similarity
messages: Belongs to the EGF-CFC (Cripto-1/FRL1/Cryptic) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

31033:LOC101065251
gene id: 31033:LOC101065251
uniprot id: Q6WNS7
names: Subcellular Location Annotation
messages: Nucleus

31033:LOC101062972
gene id: 31033:LOC101062972
uniprot id: A0A674NFZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the V-ATPase proteolipid subunit family.
messages: Membrane
messages: Proton-conducting pore forming of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex. The V1 complex consists of three catalytic AB heterodimers that form a heterohexamer, three peripheral stalks each consisting of EG heterodimers, one central rotor including subunits D and F, and the regulatory subunits C and H. The proton translocation complex V0 consists of the proton transport subunit a, a ring of proteolipid subunits c9c'', rotary subunit d, subunits e and f, and the accessory subunits.
messages: Vacuole membrane
messages: clathrin-coated vesicle membrane
messages: synaptic vesicle membrane

31033:pde1b
gene id: 31033:pde1b
uniprot id: A0A3B5KNL2
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family. PDE1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

31033:LOC101079979
gene id: 31033:LOC101079979
uniprot id: H2UGW9
names: Similarity
messages: Belongs to the PRPH2/ROM1 family.

31033:LOC101076131
gene id: 31033:LOC101076131
uniprot id: A0A674P9I2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AMY1 family.
messages: Nucleus

31033:cdo1
gene id: 31033:cdo1
uniprot id: A0A3B5KQS7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the cysteine dioxygenase family.
messages: Binds 1 Fe cation per subunit.
messages: Catalyzes the oxidation of cysteine to cysteine sulfinic acid with addition of molecular dioxygen.

31033:rps7
gene id: 31033:rps7
uniprot id: P50894
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS7 family.

31033:LOC101069190
gene id: 31033:LOC101069190
uniprot id: H2V9W5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

31033:LOC101068916
gene id: 31033:LOC101068916
uniprot id: H2UTN8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

31033:ablim3
gene id: 31033:ablim3
uniprot id: A0A674P1T7
names: Subcellular Location Annotation
messages: Cytoplasm

31033:LOC101078916
gene id: 31033:LOC101078916
uniprot id: A0A3B5KQB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. PAR subfamily.
messages: Nucleus

31033:LOC101067506
gene id: 31033:LOC101067506
uniprot id: A0A3B5KHD2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glypican family.
messages: Cell membrane
messages: Cell surface proteoglycan that bears heparan sulfate.
messages: extracellular space

31033:LOC101074582
gene id: 31033:LOC101074582
uniprot id: H2S4S3
names: Subcellular Location Annotation
messages: extracellular space

31033:LOC101061742
gene id: 31033:LOC101061742
uniprot id: H2U2P1
names: Subcellular Location Annotation
messages: Membrane

31033:LOC101072599
gene id: 31033:LOC101072599
uniprot id: A0A674PMB7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 30 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Nucleus

31033:polr3d
gene id: 31033:polr3d
uniprot id: H2S7H0
names: Subcellular Location Annotation
messages: Nucleus

31033:LOC101061729
gene id: 31033:LOC101061729
uniprot id: A0A674NMZ8
uniprot id: H2SKD4
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

31033:prl
gene id: 31033:prl
uniprot id: H2U4C4
uniprot id: Q1HAY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the somatotropin/prolactin family.
messages: Secreted

31033:hspe1
gene id: 31033:hspe1
uniprot id: A0A3B5K8B8
names: Similarity
messages: Belongs to the GroES chaperonin family.

31033:LOC101078620
gene id: 31033:LOC101078620
uniprot id: A0A3B5JYC3
uniprot id: A0A3B5KND4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dwarfin/SMAD family.
messages: Cytoplasm
messages: Nucleus

31033:rps24
gene id: 31033:rps24
uniprot id: H2SW49
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS24 family.

31033:LOC101069851
gene id: 31033:LOC101069851
uniprot id: A0A674MPZ3
names: Similarity
messages: Belongs to the TENT family.

31033:polr2d
gene id: 31033:polr2d
uniprot id: H2SFV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPB4 RNA polymerase subunit family.
messages: Nucleus

31033:dtx1
gene id: 31033:dtx1
uniprot id: H2T1I1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Deltex family.
messages: Cytoplasm

31033:jund
gene id: 31033:jund
uniprot id: Q800B1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. Jun subfamily.
messages: Nucleus

31033:eif4enif1
gene id: 31033:eif4enif1
uniprot id: H2UQ73
names: Subcellular Location Annotation
messages: Cytoplasm

31033:scube1
gene id: 31033:scube1
uniprot id: A0A674MIF4
uniprot id: A0A674MR27
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

31033:prdx2
gene id: 31033:prdx2
uniprot id: A0A3B5KK95
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.

31033:atp9a
gene id: 31033:atp9a
uniprot id: H2SV78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

31033:b3gat2
gene id: 31033:b3gat2
uniprot id: Q5CAZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 43 family.
messages: Golgi apparatus membrane
messages: Membrane

31033:ldlrad3
gene id: 31033:ldlrad3
uniprot id: H2TXQ8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

31033:LOC101075256
gene id: 31033:LOC101075256
uniprot id: A0A3B5JUK8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Endoplasmic reticulum membrane
messages: Heterotrimeric complex composed of SEC61-alpha, SEC61-beta and SEC61-gamma.
messages: Membrane
messages: Plays a crucial role in the insertion of secretory and membrane polypeptides into the ER. Required for assembly of membrane and secretory proteins. Tightly associated with membrane-bound ribosomes, either directly or through adapter proteins (By similarity). Plays a role in pronephric kidney tubule development.

31033:rtraf
gene id: 31033:rtraf
uniprot id: A0A3B5K9T5
names: Similarity
messages: Belongs to the RTRAF family.

31033:tpm2
gene id: 31033:tpm2
uniprot id: Q805C7
uniprot id: Q805C8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tropomyosin family.
messages: cytoskeleton

31033:LOC101073449
gene id: 31033:LOC101073449
uniprot id: H2UJI0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: Mitochondrion
messages: The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein (GCSH) shuttles the methylamine group of glycine from the P protein (GLDC) to the T protein (GCST).
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

31033:cops7a
gene id: 31033:cops7a
uniprot id: H2TSC0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSN7/EIF3M family. CSN7 subfamily.
messages: Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, JUN, I-kappa-B-alpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively.
messages: Cytoplasm
messages: Nucleus

31033:mbnl2a
gene id: 31033:mbnl2a
uniprot id: Q6Q2B2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Tissue Specificity
messages: Belongs to the muscleblind family.
messages: Cytoplasm
messages: Expressed in fast and slow myotomal muscle, heart, liver, skin, brain and testis.
messages: Involved in pre-mRNA alternative splicing regulation. RNA-binding protein that binds to 5'ACACCC-3' core sequence (By similarity).
messages: Nucleus

31033:tdrd3
gene id: 31033:tdrd3
uniprot id: H2V4B7
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus
messages: Scaffolding protein that specifically recognizes and binds dimethylarginine-containing proteins. In nucleus, acts as a coactivator: recognizes and binds asymmetric dimethylation on the core histone tails associated with transcriptional activation (H3R17me2a and H4R3me2a) and recruits proteins at these arginine-methylated loci. In cytoplasm, may play a role in the assembly and/or disassembly of mRNA stress granules and in the regulation of translation of target mRNAs by binding Arg/Gly-rich motifs (GAR) in dimethylarginine-containing proteins.

31033:mark4
gene id: 31033:mark4
uniprot id: H2STG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.
messages: dendrite

31033:LOC101064407
gene id: 31033:LOC101064407
uniprot id: H2TR38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

31033:ccn1
gene id: 31033:ccn1
uniprot id: A0A3B5K3S9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCN family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

31033:LOC101068693
gene id: 31033:LOC101068693
uniprot id: H2U9Q6
names: Subcellular Location Annotation
messages: Membrane

31033:kpna4
gene id: 31033:kpna4
uniprot id: H2SUD5
names: Similarity
messages: Belongs to the importin alpha family.

31033:lrfn2
gene id: 31033:lrfn2
uniprot id: H2TI92
names: Subcellular Location Annotation
messages: Membrane

31033:tph2
gene id: 31033:tph2
uniprot id: Q6IWN1
names: Similarity
messages: Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.

31033:LOC101073225
gene id: 31033:LOC101073225
uniprot id: H2U8P4
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

31033:LOC101072120
gene id: 31033:LOC101072120
uniprot id: H2TET8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

31033:gtpbp10
gene id: 31033:gtpbp10
uniprot id: A0A3B5KKJ9
names: Similarity
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.

31033:LOC101075957
gene id: 31033:LOC101075957
uniprot id: A0A3B5K044
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family.
messages: Nucleus

31033:fam110b
gene id: 31033:fam110b
uniprot id: H2T2C0
names: Similarity
messages: Belongs to the FAM110 family.

31033:rrn3
gene id: 31033:rrn3
uniprot id: A0A674NPN3
names: Similarity
messages: Belongs to the RRN3 family.

31033:ebag9
gene id: 31033:ebag9
uniprot id: H2S9V9
names: Function
names: Subcellular Location Annotation
messages: Golgi apparatus membrane
messages: May participate in suppression of cell proliferation and induces apoptotic cell death through activation of interleukin-1-beta converting enzyme (ICE)-like proteases.

31033:spsb3
gene id: 31033:spsb3
uniprot id: H2SIH5
names: Function
names: Similarity
messages: Belongs to the SPSB family.
messages: May be a substrate recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.

31033:atp5f1c
gene id: 31033:atp5f1c
uniprot id: H2TPW6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(1) domain and the central stalk which is part of the complex rotary element. The gamma subunit protrudes into the catalytic domain formed of alpha(3)beta(3). Rotation of the central stalk against the surrounding alpha(3)beta(3) subunits leads to hydrolysis of ATP in three separate catalytic sites on the beta subunits.

31033:oaz1
gene id: 31033:oaz1
uniprot id: H2V981
names: Similarity
messages: Belongs to the ODC antizyme family.

31033:LOC101069612
gene id: 31033:LOC101069612
uniprot id: H2TFU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 99 family.
messages: Golgi apparatus membrane
messages: Membrane

31033:LOC105417139
gene id: 31033:LOC105417139
uniprot id: A0A674PRJ4
names: Similarity
messages: Belongs to the SYCE family.

31033:ubac2
gene id: 31033:ubac2
uniprot id: H2TIA8
names: Subcellular Location Annotation
messages: Membrane

31033:pfdn4
gene id: 31033:pfdn4
uniprot id: H2T3G3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prefoldin subunit beta family.
messages: Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.
messages: Heterohexamer of two PFD-alpha type and four PFD-beta type subunits.

31033:LOC101063622
gene id: 31033:LOC101063622
uniprot id: A0A674NMK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OST3/OST6 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

31033:rpl10a
gene id: 31033:rpl10a
uniprot id: H2UWL3
names: Similarity
messages: Belongs to the universal ribosomal protein uL1 family.

31033:LOC101075245
gene id: 31033:LOC101075245
uniprot id: H2V022
names: Function
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
messages: Cytosolic CRABPs may regulate the access of retinoic acid to the nuclear retinoic acid receptors.

31033:KEF89 p02
gene id: 31033:KEF89_p02
uniprot id: Q8HCV4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.
messages: Mitochondrion membrane

31033:mcrip2
gene id: 31033:mcrip2
uniprot id: H2U4W8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCRIP family.
messages: Nucleus
messages: Stress granule

31033:LOC101065874
gene id: 31033:LOC101065874
uniprot id: H2UVB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

31033:LOC101064648
gene id: 31033:LOC101064648
uniprot id: H2UVH7
names: Similarity
messages: Belongs to the cytochrome P450 family.

31033:LOC101072315
gene id: 31033:LOC101072315
uniprot id: A0A3B5KHE0
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 2 family.
messages: Interconverts simultaneously and stereospecifically pyruvate and lactate with concomitant interconversion of NADH and NAD(+).

31033:LOC101078618
gene id: 31033:LOC101078618
uniprot id: H2TM51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Cell membrane
messages: Membrane

31033:ut-c
gene id: 31033:ut-c
uniprot id: Q5W8V7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urea transporter family.
messages: Cell membrane
messages: Membrane

31033:LOC101071539
gene id: 31033:LOC101071539
uniprot id: A0A674NDJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTF2H2 family.
messages: Nucleus

31033:tmem147
gene id: 31033:tmem147
uniprot id: A0A3B5KNE2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Endoplasmic reticulum membrane
messages: Membrane

31033:acer1
gene id: 31033:acer1
uniprot id: H2T6Q1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alkaline ceramidase family.
messages: Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid.
messages: Membrane

31033:nppc
gene id: 31033:nppc
uniprot id: Q805D3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the natriuretic peptide family.
messages: Exhibits natriuretic and vasodepressant activity. Has cGMP-stimulating activity. May help to regulate body fluid homeostasis in a variety of aquatic environments.
messages: Secreted

31033:LOC101068056
gene id: 31033:LOC101068056
uniprot id: Q2PR37
names: Subcellular Location Annotation
messages: Membrane

31033:LOC101066247
gene id: 31033:LOC101066247
uniprot id: A0A3B5KBA7
names: Subcellular Location Annotation
names: Subunit
messages: Apical cell membrane
messages: Cell membrane
messages: Homodimer.
messages: Membrane

31033:LOC105418057
gene id: 31033:LOC105418057
uniprot id: A0A674NTF1
names: Similarity
messages: Belongs to the NipSnap family.

31033:LOC101077315
gene id: 31033:LOC101077315
uniprot id: H2U0L0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vestigial family.
messages: Nucleus

31033:LOC101063692
gene id: 31033:LOC101063692
uniprot id: H2TP05
names: Similarity
messages: Belongs to the PI3K p85 subunit family.

31033:LOC101063611
gene id: 31033:LOC101063611
uniprot id: H2SM81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enhancer of polycomb family.
messages: Nucleus

31033:LOC101066738
gene id: 31033:LOC101066738
uniprot id: H2TWT4
names: Subcellular Location Annotation
messages: Nucleus

31033:LOC101062006
gene id: 31033:LOC101062006
uniprot id: A0A674MAZ0
names: Similarity
messages: Belongs to the cyclin family. Cyclin AB subfamily.

31033:LOC101078030
gene id: 31033:LOC101078030
uniprot id: A0A674PPP5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Homodimer. Heterodimer with HTR1D.
messages: Membrane

31033:LOC101071112
gene id: 31033:LOC101071112
uniprot id: A0A674P5X5
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

31033:otud7b
gene id: 31033:otud7b
uniprot id: H2U9M5
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

31033:nudt21
gene id: 31033:nudt21
uniprot id: H2V9Y4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Nudix hydrolase family. CPSF5 subfamily.
messages: Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs. CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals). Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation. The CFIm complex acts as a key regulator of cleavage and polyadenylation site choice during APA through its binding to 5'-UGUA-3' elements localized in the 3'-untranslated region (UTR) for a huge number of pre-mRNAs.
messages: Cytoplasm
messages: Homodimer (via N- and C-terminus); binds RNA as homodimer. Component of the cleavage factor Im (CFIm) complex.
messages: Nucleus

31033:cyp17a1
gene id: 31033:cyp17a1
uniprot id: A7U484
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Conversion of pregnenolone and progesterone to their 17-alpha-hydroxylated products and subsequently to dehydroepiandrosterone (DHEA) and androstenedione. Catalyzes both the 17-alpha-hydroxylation and the 17,20-lyase reaction.
messages: Membrane

31033:LOC101079686
gene id: 31033:LOC101079686
uniprot id: A0A3B5JXQ9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

31033:LOC101062038
gene id: 31033:LOC101062038
uniprot id: H2UBY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSG1 family.
messages: Membrane

31033:hnf1b
gene id: 31033:hnf1b
uniprot id: A0A674MAE3
uniprot id: A0A674NTJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HNF1 homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

31033:wdr83os
gene id: 31033:wdr83os
uniprot id: A0A674N8N0
names: Similarity
messages: Belongs to the Asterix family.

31033:miga2
gene id: 31033:miga2
uniprot id: H2VCR9
names: Similarity
messages: Belongs to the mitoguardin family.

31033:elk3
gene id: 31033:elk3
uniprot id: H2V2E8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

31033:LOC101076808
gene id: 31033:LOC101076808
uniprot id: A0A674PRU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

31033:LOC101064722
gene id: 31033:LOC101064722
uniprot id: A0A3B5KIX4
names: Similarity
messages: Belongs to the DOK family. Type A subfamily.

31033:LOC445940
gene id: 31033:LOC445940
uniprot id: Q804X1
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular space

31033:stc2
gene id: 31033:stc2
uniprot id: Q5IRA9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the stanniocalcin family.
messages: Homodimer; disulfide-linked.
messages: Its primary function is the prevention of hypercalcemia. Upon release into the circulation, it lowers calcium transport by the gills, thereby reducing its rate of influx from the environment into the extracellular compartment. STC also stimulates phosphate reabsorption by renal proximal tubules. The consequence of this action is increased levels of plasma phosphate, which combines with excess calcium and promotes its disposal into bone and scales.

31033:sppl2a
gene id: 31033:sppl2a
uniprot id: H2SR20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A22B family.
messages: Membrane

31033:bloc1s6
gene id: 31033:bloc1s6
uniprot id: A0A3B5KAV5
names: Function
names: Similarity
messages: Belongs to the BLOC1S6 family.
messages: Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. May play a role in intracellular vesicle trafficking, particularly in the vesicle-docking and fusion process.

31033:polr3k
gene id: 31033:polr3k
uniprot id: H2TZ33
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.
messages: Component of the RNA polymerase III (Pol III) complex consisting of 17 subunits.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: nucleolus

31033:gkap1
gene id: 31033:gkap1
uniprot id: H2TUF1
names: Similarity
messages: Belongs to the GKAP1 family.

31033:LOC101069451
gene id: 31033:LOC101069451
uniprot id: H2SRX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family. KCNJ6 subfamily.
messages: Membrane

31033:homer2
gene id: 31033:homer2
uniprot id: H2V3M2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Homer family.
messages: Postsynaptic density
messages: Synapse

31033:LOC101079549
gene id: 31033:LOC101079549
uniprot id: A0A3B5K5U3
names: Similarity
messages: Belongs to the arrestin family.

31033:rpf1
gene id: 31033:rpf1
uniprot id: A0A3B5K696
names: Subcellular Location Annotation
messages: nucleolus

31033:LOC101079484
gene id: 31033:LOC101079484
uniprot id: H2RVP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

31033:LOC101074053
gene id: 31033:LOC101074053
uniprot id: A0A674MK50
names: Similarity
messages: Belongs to the CD225/Dispanin family.

31033:nck2
gene id: 31033:nck2
uniprot id: H2UC75
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Endoplasmic reticulum

31033:ptn
gene id: 31033:ptn
uniprot id: H2UUT2
names: Similarity
messages: Belongs to the pleiotrophin family.

31033:asic1
gene id: 31033:asic1
uniprot id: A0A674MRE7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

31033:eftud2
gene id: 31033:eftud2
uniprot id: H2UYE7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Nucleus

31033:tsn
gene id: 31033:tsn
uniprot id: H2UDE5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the translin family.
messages: DNA-binding protein that specifically recognizes consensus sequences at the breakpoint junctions in chromosomal translocations, mostly involving immunoglobulin (Ig)/T-cell receptor gene segments. Seems to recognize single-stranded DNA ends generated by staggered breaks occurring at recombination hot spots.
messages: Exhibits both single-stranded and double-stranded endoribonuclease activity. May act as an activator of RNA-induced silencing complex (RISC) by facilitating endonucleolytic cleavage of the siRNA passenger strand.
messages: Nucleus
messages: Ring-shaped heterooctamer of six TSN and two TSNAX subunits, DNA/RNA binding occurs inside the ring.

31033:LOC101074356
gene id: 31033:LOC101074356
uniprot id: A0A674P297
names: Subcellular Location Annotation
messages: extracellular space

31033:prpf38b
gene id: 31033:prpf38b
uniprot id: H2TYE2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRP38 family.
messages: May be required for pre-mRNA splicing.
messages: Nucleus

31033:dusp8
gene id: 31033:dusp8
uniprot id: H2SZX1
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.

31033:tmem30a
gene id: 31033:tmem30a
uniprot id: H2TK87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDC50/LEM3 family.
messages: Cell membrane
messages: Golgi apparatus
messages: Membrane
messages: secretory vesicle membrane

31033:rara
gene id: 31033:rara
uniprot id: Q9W5Z3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Composed of three domains: a modulating N-terminal domain, a DNA-binding domain and a C-terminal ligand-binding domain.
messages: Heterodimer; with an rxr molecule. Binds DNA preferentially as a rar/rxr heterodimer.
messages: Nucleus
messages: Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The rar/rxr heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5 (By similarity).
messages: The 9aaTAD motif is a transactivation domain present in a large number of yeast and animal transcription factors.

31033:pox1
gene id: 31033:pox1
uniprot id: Q8AWX6
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

31033:slc25a34
gene id: 31033:slc25a34
uniprot id: A0A3B5JZI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

31033:scrn3
gene id: 31033:scrn3
uniprot id: Q1KKU0
names: Similarity
messages: Belongs to the peptidase C69 family. Secernin subfamily.

31033:map4k3
gene id: 31033:map4k3
uniprot id: A0A674MK70
uniprot id: A0A674NYG8
names: Function
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
messages: May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway.

31033:tspan4
gene id: 31033:tspan4
uniprot id: A0A674NPH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

31033:cnep1r1
gene id: 31033:cnep1r1
uniprot id: A0A674MFC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CNEP1R1 family.
messages: Cytoplasm
messages: Membrane
messages: Nucleus membrane

31033:klc2
gene id: 31033:klc2
uniprot id: H2SVZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the kinesin light chain family.
messages: Kinesin is a microtubule-associated force-producing protein that play a role in organelle transport.
messages: Oligomeric complex composed of two heavy chains and two light chains.
messages: cytoskeleton

31033:tie1
gene id: 31033:tie1
uniprot id: H2VDJ8
names: Caution
names: Subcellular Location Annotation
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

31033:LOC101063229
gene id: 31033:LOC101063229
uniprot id: H2V2C8
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

31033:hoxb5
gene id: 31033:hoxb5
uniprot id: Q1KKX0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

31033:LOC101061565
gene id: 31033:LOC101061565
uniprot id: A0A674NJ59
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

31033:rps27a
gene id: 31033:rps27a
uniprot id: H2TSM1
names: Similarity
names: Subunit
messages: In the C-terminal section; belongs to the eukaryotic ribosomal protein eS31 family.
messages: In the N-terminal section; belongs to the ubiquitin family.
messages: Ribosomal protein S27a is part of the 40S ribosomal subunit.

31033:ppara1
gene id: 31033:ppara1
uniprot id: A4PE11
uniprot id: H2UYP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Nucleus

31033:pdlim3
gene id: 31033:pdlim3
uniprot id: H2SMK8
names: Subcellular Location Annotation
messages: Z line

31033:ndufaf7
gene id: 31033:ndufaf7
uniprot id: H2USL4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Arginine methyltransferase involved in the assembly or stability of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I).
messages: Belongs to the NDUFAF7 family.
messages: Mitochondrion

31033:arcn1
gene id: 31033:arcn1
uniprot id: H2TNI1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adaptor complexes medium subunit family. Delta-COP subfamily.
messages: COPI-coated vesicle membrane
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Membrane
messages: Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.

31033:snf8
gene id: 31033:snf8
uniprot id: H2TYV4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SNF8 family.
messages: Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs.
messages: Component of the endosomal sorting complex required for transport II (ESCRT-II).

31033:dhrs11
gene id: 31033:dhrs11
uniprot id: H2SRY7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

31033:LOC101071194
gene id: 31033:LOC101071194
uniprot id: H2TK05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM41 family.
messages: Membrane

31033:gucy1a1
gene id: 31033:gucy1a1
uniprot id: Q90VV5
names: Similarity
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.

31033:tmem88b
gene id: 31033:tmem88b
uniprot id: H2TKD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM88 family.
messages: Membrane

31033:LOC101068135
gene id: 31033:LOC101068135
uniprot id: A0A674M9V1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

31033:LOC101063501
gene id: 31033:LOC101063501
uniprot id: H2U5C0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

31033:capn9
gene id: 31033:capn9
uniprot id: H2S155
names: Similarity
messages: Belongs to the peptidase C2 family.

31033:gabarap
gene id: 31033:gabarap
uniprot id: H2TXA4
names: Similarity
messages: Belongs to the ATG8 family.

31033:ppard
gene id: 31033:ppard
uniprot id: A4PE13
uniprot id: H2UWE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

31033:cog4
gene id: 31033:cog4
uniprot id: H2VA36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COG4 family.
messages: Golgi apparatus membrane

31033:LOC101069022
gene id: 31033:LOC101069022
uniprot id: H2SYZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NIP3 family.
messages: Membrane

31033:LOC101079598
gene id: 31033:LOC101079598
uniprot id: A0A3B5KRU7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

31033:capn7
gene id: 31033:capn7
uniprot id: H2SDL1
names: Similarity
messages: Belongs to the peptidase C2 family.

31033:yju2
gene id: 31033:yju2
uniprot id: A0A3B5K8W2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CWC16 family. YJU2 subfamily.
messages: Component of the spliceosome. Present in the activated B complex, the catalytically activated B* complex which catalyzes the branching, the catalytic step 1 C complex catalyzing the exon ligation, and the postcatalytic P complex containing the ligated exons (mRNA) and the excised lariat intron.
messages: Nucleus
messages: Part of the spliceosome which catalyzes two sequential transesterification reactions, first the excision of the non-coding intron from pre-mRNA and then the ligation of the coding exons to form the mature mRNA. Plays a role in stabilizing the structure of the spliceosome catalytic core and docking of the branch helix into the active site, producing 5'-exon and lariat intron-3'-intermediates. May protect cells from TP53-dependent apoptosis upon dsDNA break damage through association with PRP19-CD5L complex.

31033:LOC101070524
gene id: 31033:LOC101070524
uniprot id: H2RXJ8
names: Subcellular Location Annotation
messages: Nucleus

31033:LOC101076647
gene id: 31033:LOC101076647
uniprot id: H2SK19
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 13 family.
messages: Golgi apparatus membrane
messages: Initiates complex N-linked carbohydrate formation. Essential for the conversion of high-mannose to hybrid and complex N-glycans.
messages: Membrane
messages: The cofactor is mostly bound to the substrate.

31033:LOC101071822
gene id: 31033:LOC101071822
uniprot id: A0A3B5K6G0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Nudix hydrolase family.
messages: Cytoplasm
messages: May contribute to the regulation of cell proliferation.
messages: Mitochondrion
messages: Monomer and homodimer.
messages: Nucleus

31033:LOC101071898
gene id: 31033:LOC101071898
uniprot id: H2UYF1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycoprotein hormones subunit beta family.
messages: Heterodimer of an alpha and a beta chain.
messages: Involved in gametogenesis and steroidogenesis.
messages: Secreted

31033:mct4b
gene id: 31033:mct4b
uniprot id: E7FKY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.
messages: Membrane

31033:exoc2
gene id: 31033:exoc2
uniprot id: H2RVL5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SEC5 family.
messages: Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.
messages: Component of the exocyst complex.

31033:cbl
gene id: 31033:cbl
uniprot id: A0A674MP59
names: Domain
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: E3 ubiquitin-protein ligase which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, and transfers it to substrates, generally promoting their degradation by the proteasome.
messages: The N-terminus is composed of the phosphotyrosine binding (PTB) domain, a short linker region and the RING-type zinc finger. The PTB domain, which is also called TKB (tyrosine kinase binding) domain, is composed of three different subdomains: a four-helix bundle (4H), a calcium-binding EF hand and a divergent SH2 domain.

31033:araf
gene id: 31033:araf
uniprot id: Q5NSW1
names: Similarity
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. RAF subfamily.

31033:hddc2
gene id: 31033:hddc2
uniprot id: H2UKJ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HDDC2 family.
messages: Catalyzes the dephosphorylation of the nucleoside 5'-monophosphates deoxyadenosine monophosphate (dAMP), deoxycytidine monophosphate (dCMP), deoxyguanosine monophosphate (dGMP) and deoxythymidine monophosphate (dTMP).
messages: Homodimer.

31033:hmgcs1
gene id: 31033:hmgcs1
uniprot id: H2TS58
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. HMG-CoA synthase family.
messages: Catalyzes the condensation of acetyl-CoA with acetoacetyl-CoA to form HMG-CoA.

31033:anapc13
gene id: 31033:anapc13
uniprot id: A0A3B5K040
names: Function
names: Similarity
messages: Belongs to the APC13 family.
messages: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.

31033:mrpl42
gene id: 31033:mrpl42
uniprot id: A0A3B5KSN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL42 family.
messages: Mitochondrion

31033:LOC101069286
gene id: 31033:LOC101069286
uniprot id: A0A674MZT5
names: Similarity
messages: Belongs to the galactose-3-O-sulfotransferase family.

31033:LOC101077450
gene id: 31033:LOC101077450
uniprot id: H2RMS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NIP3 family.
messages: Membrane

31033:dcps
gene id: 31033:dcps
uniprot id: Q7T3R2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HIT family.
messages: Decapping scavenger enzyme that catalyzes the cleavage of a residual cap structure following the degradation of mRNAs by the 3'->5' exosome-mediated mRNA decay pathway.
messages: Homodimer. Associates with components of the exosome multienzyme ribonuclease complex, such as EXOSC3 and EXOSC4. Interacts with NDOR1.
messages: Nucleus

31033:LOC101074115
gene id: 31033:LOC101074115
uniprot id: H2VES7
names: Similarity
messages: Belongs to the actin family.

31033:armc8
gene id: 31033:armc8
uniprot id: H2UP57
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

31033:rpl3l
gene id: 31033:rpl3l
uniprot id: A0A674NUS0
names: Similarity
messages: Belongs to the universal ribosomal protein uL3 family.

31033:LOC101067706
gene id: 31033:LOC101067706
uniprot id: A0A674MYY5
names: Similarity
messages: Belongs to the PPP phosphatase family.

31033:LOC101072554
gene id: 31033:LOC101072554
uniprot id: A0A674NGT3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

31033:orc2
gene id: 31033:orc2
uniprot id: H2S924
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ORC2 family.
messages: Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.
messages: Component of the origin recognition complex (ORC).
messages: Nucleus

31033:LOC101075029
gene id: 31033:LOC101075029
uniprot id: H2S886
names: Similarity
messages: Belongs to the TBP family.

31033:lect2
gene id: 31033:lect2
uniprot id: A0A3B5KVM1
names: Similarity
messages: Belongs to the LECT2/MIM-1 family.

31033:LOC101072849
gene id: 31033:LOC101072849
uniprot id: A0A674PFR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR2 subfamily.
messages: Nucleus

31033:ants6
gene id: 31033:ants6
uniprot id: Q5KSP4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Catalyzes the exchange of ADP and ATP across the membrane.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Monomer.

31033:LOC101073683
gene id: 31033:LOC101073683
uniprot id: A0A3B5K1J1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAR6 family.
messages: Cytoplasm
messages: tight junction

31033:scnm1
gene id: 31033:scnm1
uniprot id: H2RQA3
names: Function
names: Subcellular Location Annotation
messages: Nucleus speckle
messages: Plays a role in alternative splicing of pre-mRNAs, possibly by contributing to the selection of non-consensus donor sites.
messages: nucleoplasm

31033:dio3
gene id: 31033:dio3
uniprot id: B1B572
names: Function
names: Similarity
messages: Belongs to the iodothyronine deiodinase family.
messages: Responsible for the deiodination of T4 (3,5,3',5'-tetraiodothyronine).

31033:LOC101061744
gene id: 31033:LOC101061744
uniprot id: A0A3B5K553
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane

31033:tnfsf13b
gene id: 31033:tnfsf13b
uniprot id: A0A3B5JW09
names: Similarity
messages: Belongs to the tumor necrosis factor family.

31033:LOC101079447
gene id: 31033:LOC101079447
uniprot id: H2V3B5
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

31033:LOC101070493
gene id: 31033:LOC101070493
uniprot id: H2UR24
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial Rho GTPase family.
messages: Membrane
messages: Mitochondrial GTPase involved in mitochondrial trafficking.
messages: Mitochondrion outer membrane

31033:LOC101071076
gene id: 31033:LOC101071076
uniprot id: H2TQP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NPY family.
messages: Secreted

31033:LOC101064982
gene id: 31033:LOC101064982
uniprot id: H2TII2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POMC family.
messages: Endogenous opiate.
messages: Secreted
messages: Stimulates the adrenal glands to release cortisol.

31033:LOC101061396
gene id: 31033:LOC101061396
uniprot id: A0A3B5KRU7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

31033:nop56
gene id: 31033:nop56
uniprot id: A0A674MP14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOP5/NOP56 family.
messages: nucleolus

31033:LOC101069572
gene id: 31033:LOC101069572
uniprot id: H2SWT0
names: Similarity
messages: Belongs to the eukaryotic initiation factor 4E family.

31033:LOC115246426
gene id: 31033:LOC115246426
uniprot id: A0A3B5KB33
names: Subcellular Location Annotation
messages: Membrane

31033:cat
gene id: 31033:cat
uniprot id: A0A6D2XID5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the catalase family.
messages: Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.
messages: Peroxisome

31033:LOC101069659
gene id: 31033:LOC101069659
uniprot id: H2S901
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

31033:cebpd
gene id: 31033:cebpd
uniprot id: A0A3B5KNG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. C/EBP subfamily.
messages: Nucleus

31033:aoc1
gene id: 31033:aoc1
uniprot id: H2V9H0
names: Cofactor
names: PTM
names: Similarity
messages: Belongs to the copper/topaquinone oxidase family.
messages: Contains 1 topaquinone per subunit.
messages: Topaquinone (TPQ) is generated by copper-dependent autoxidation of a specific tyrosyl residue.

31033:LOC101074539
gene id: 31033:LOC101074539
uniprot id: A0A674NYF3
names: Similarity
messages: Belongs to the TMEM106 family.

31033:slc7a9
gene id: 31033:slc7a9
uniprot id: H2RKJ2
names: Subcellular Location Annotation
messages: Membrane

31033:dot1l
gene id: 31033:dot1l
uniprot id: H2V929
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. DOT1 family.
messages: Histone methyltransferase that specifically trimethylates histone H3 to form H3K79me3. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks. Nucleosomes are preferred as substrate compared to free histone.
messages: In contrast to other lysine histone methyltransferases, it does not contain a SET domain, suggesting the existence of another mechanism for methylation of lysine residues of histones.
messages: Nucleus

31033:ppie
gene id: 31033:ppie
uniprot id: Q8QGJ6
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family. PPIase E subfamily.
messages: Catalyzes the cis-trans isomerization of proline imidic peptide bonds in proteins.

31033:tacr1
gene id: 31033:tacr1
uniprot id: I4IY87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

31033:LOC101068629
gene id: 31033:LOC101068629
uniprot id: A0A3B5JXE7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

31033:LOC101076045
gene id: 31033:LOC101076045
uniprot id: A0A674PPN3
names: Cofactor
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

31033:LOC101069212
gene id: 31033:LOC101069212
uniprot id: A0A6D2X1D0
names: Subcellular Location Annotation
messages: extracellular space

31033:xkr4
gene id: 31033:xkr4
uniprot id: H2TIE7
uniprot id: Q5GH51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XK family.
messages: Membrane

31033:clstn1
gene id: 31033:clstn1
uniprot id: A0A674P963
uniprot id: A0A674PRJ7
uniprot id: H2TPX0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Golgi apparatus membrane
messages: Membrane

31033:dna2
gene id: 31033:dna2
uniprot id: H2SI79
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA2/NAM7 helicase family.
messages: Key enzyme involved in DNA replication and DNA repair. Involved in Okazaki fragments processing by cleaving long flaps that escape FEN1: flaps that are longer than 27 nucleotides are coated by replication protein A complex (RPA), leading to recruit DNA2 which cleaves the flap until it is too short to bind RPA and becomes a substrate for FEN1. Also involved in 5'-end resection of DNA during double-strand break (DSB) repair by mediating the cleavage of 5'-ssDNA.
messages: Mitochondrion
messages: Nucleus

31033:LOC101068806
gene id: 31033:LOC101068806
uniprot id: H2SFM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

31033:sbf1
gene id: 31033:sbf1
uniprot id: A0A674MZF6
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.

31033:LOC101074730
gene id: 31033:LOC101074730
uniprot id: H2TT08
names: Similarity
messages: Belongs to the PTEN phosphatase protein family.

31033:eci1
gene id: 31033:eci1
uniprot id: H2UJG4
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

31033:nlgn2a
gene id: 31033:nlgn2a
uniprot id: D2X2G7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type-B carboxylesterase/lipase family.
messages: Cell membrane
messages: Membrane

31033:LOC101062683
gene id: 31033:LOC101062683
uniprot id: A0A3B5KWD8
names: Similarity
messages: Belongs to the SCO1/2 family.

31033:LOC101062552
gene id: 31033:LOC101062552
uniprot id: A0A674NR91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily.
messages: Membrane

31033:LOC101063177
gene id: 31033:LOC101063177
uniprot id: A0A674NCB8
names: Subcellular Location Annotation
messages: Membrane

31033:mrpl16
gene id: 31033:mrpl16
uniprot id: H2V4K4
names: Similarity
messages: Belongs to the universal ribosomal protein uL16 family.

31033:cwf19l1
gene id: 31033:cwf19l1
uniprot id: H2SMS1
names: Similarity
messages: Belongs to the CWF19 family.

31033:nim1k
gene id: 31033:nim1k
uniprot id: H2UNU5
names: Similarity
messages: Belongs to the protein kinase superfamily.

31033:sh3pxd2b
gene id: 31033:sh3pxd2b
uniprot id: H2RVN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SH3PXD2 family.
messages: Cytoplasm
messages: podosome

31033:LOC101062358
gene id: 31033:LOC101062358
uniprot id: H2TY87
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the junctophilin family.
messages: Cell membrane
messages: Endoplasmic reticulum membrane
messages: Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels.
messages: Membrane

31033:sdr16c5
gene id: 31033:sdr16c5
uniprot id: H2TMG5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

31033:LOC101071438
gene id: 31033:LOC101071438
uniprot id: A0A674PK66
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

31033:vps25
gene id: 31033:vps25
uniprot id: H2STK3
names: Similarity
messages: Belongs to the VPS25 family.

31033:cdk20
gene id: 31033:cdk20
uniprot id: A0A674MRU8
names: Similarity
messages: Belongs to the protein kinase superfamily.

31033:timp3
gene id: 31033:timp3
uniprot id: Q4JF88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protease inhibitor I35 (TIMP) family.
messages: extracellular matrix

31033:traf2
gene id: 31033:traf2
uniprot id: H2VF06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TNF receptor-associated factor family.
messages: Cytoplasm

31033:LOC101070533
gene id: 31033:LOC101070533
uniprot id: Q2PR38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

31033:necap2
gene id: 31033:necap2
uniprot id: H2TPR9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NECAP family.
messages: Involved in endocytosis.
messages: clathrin-coated vesicle membrane

31033:LOC101064242
gene id: 31033:LOC101064242
uniprot id: A0A6D2W9X6
names: Similarity
messages: Belongs to the R-spondin family.

31033:med21
gene id: 31033:med21
uniprot id: A0A674NFL1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 21 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

31033:ebna1bp2
gene id: 31033:ebna1bp2
uniprot id: H2VDM3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EBP2 family.
messages: Required for the processing of the 27S pre-rRNA.
messages: nucleolus

31033:ppp4r3a
gene id: 31033:ppp4r3a
uniprot id: A0A674MEV7
names: Similarity
messages: Belongs to the SMEK family.

31033:cenph
gene id: 31033:cenph
uniprot id: A0A3B5KA53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CENP-H/MCM16 family.
messages: Nucleus
messages: kinetochore

31033:LOC101072104
gene id: 31033:LOC101072104
uniprot id: A0A674PBA6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
messages: Membrane
messages: Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization.

31033:ppara2
gene id: 31033:ppara2
uniprot id: A4PE12
uniprot id: H2SPP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

31033:kcng1
gene id: 31033:kcng1
uniprot id: H2ST45
names: Subcellular Location Annotation
messages: Membrane

31033:foxe1
gene id: 31033:foxe1
uniprot id: H2TQJ1
names: Subcellular Location Annotation
messages: Nucleus

31033:tpt1
gene id: 31033:tpt1
uniprot id: H2VA86
names: Similarity
messages: Belongs to the TCTP family.

31033:hgs
gene id: 31033:hgs
uniprot id: H2TYB1
names: Subcellular Location Annotation
messages: Early endosome membrane

31033:rack1
gene id: 31033:rack1
uniprot id: H2RMD4
names: Similarity
messages: Belongs to the WD repeat G protein beta family. Ribosomal protein RACK1 subfamily.

31033:LOC101077600
gene id: 31033:LOC101077600
uniprot id: A0A3B5K3Q2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat SMU1 family.
messages: Nucleus speckle

31033:lsm12
gene id: 31033:lsm12
uniprot id: H2SYL5
names: Similarity
messages: Belongs to the LSM12 family.

31033:smc1b
gene id: 31033:smc1b
uniprot id: Q802S2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMC family. SMC1 subfamily.
messages: Chromosome
messages: Nucleus

31033:abi2
gene id: 31033:abi2
uniprot id: A0A674NMY8
uniprot id: H2TG76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABI family.
messages: cytoskeleton
messages: filopodium
messages: lamellipodium

31033:nip7
gene id: 31033:nip7
uniprot id: H2RK92
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NIP7 family.
messages: Interacts with pre-ribosome complex.
messages: Required for proper 34S pre-rRNA processing and 60S ribosome subunit assembly.
messages: nucleolus

31033:LOC101070417
gene id: 31033:LOC101070417
uniprot id: A0A3B5KCW9
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

31033:LOC101072910
gene id: 31033:LOC101072910
uniprot id: A0A3B5K3I1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 2 family.
messages: Golgi apparatus membrane
messages: Membrane

31033:LOC101064782
gene id: 31033:LOC101064782
uniprot id: H2U4P2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Clp1 family. Clp1 subfamily.
messages: Component of the tRNA splicing endonuclease complex. Component of pre-mRNA cleavage complex II (CF-II).
messages: Nucleus
messages: Polynucleotide kinase that can phosphorylate the 5'-hydroxyl groups of double-stranded RNA (dsRNA), single-stranded RNA (ssRNA), double stranded DNA (dsDNA) and double-stranded DNA:RNA hybrids. dsRNA is phosphorylated more efficiently than dsDNA, and the RNA component of a DNA:RNA hybrid is phosphorylated more efficiently than the DNA component. Appears to have roles in both tRNA splicing and mRNA 3'-end formation. Component of the tRNA splicing endonuclease complex. Phosphorylates the 5'-terminus of the tRNA 3'-exon during tRNA splicing; this phosphorylation event is a prerequisite for the subsequent ligation of the two exon halves and the production of a mature tRNA. Component of the pre-mRNA cleavage complex II (CF-II), which seems to be required for mRNA 3'-end formation. Also phosphorylates the 5'-terminus of exogenously introduced short interfering RNAs (siRNAs), which is a necessary prerequisite for their incorporation into the RNA-induced silencing complex (RISC). However, endogenous siRNAs and microRNAs (miRNAs) that are produced by the cleavage of dsRNA precursors by DICER1 already contain a 5'-phosphate group, so this protein may be dispensible for normal RNA-mediated gene silencing.

31033:usp49
gene id: 31033:usp49
uniprot id: H2TC04
names: Similarity
messages: Belongs to the peptidase C19 family.

31033:tmem18
gene id: 31033:tmem18
uniprot id: A0A674P6C3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM18 family.
messages: Membrane
messages: Nucleus membrane

31033:LOC101066651
gene id: 31033:LOC101066651
uniprot id: H2SNJ2
uniprot id: H2SNJ3
uniprot id: H2SNJ4
uniprot id: H2V7J5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dynactin 150 kDa subunit family.
messages: cell cortex
messages: cytoskeleton

31033:timp2
gene id: 31033:timp2
uniprot id: Q4JF85
names: Similarity
messages: Belongs to the protease inhibitor I35 (TIMP) family.

31033:rasgrp2
gene id: 31033:rasgrp2
uniprot id: H2U1D4
names: Similarity
messages: Belongs to the RASGRP family.

31033:LOC101076573
gene id: 31033:LOC101076573
uniprot id: H2UDP7
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

31033:ipmk
gene id: 31033:ipmk
uniprot id: A0A674PPM2
names: Similarity
messages: Belongs to the inositol phosphokinase (IPK) family.

31033:cldn30d
gene id: 31033:cldn30d
uniprot id: Q6E5R1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: tight junction

31033:coq7
gene id: 31033:coq7
uniprot id: H2TZ78
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COQ7 family.
messages: Binds 2 iron ions per subunit.
messages: Catalyzes the hydroxylation of 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) during ubiquinone biosynthesis. Has also a structural role in the COQ enzyme complex, stabilizing other COQ polypeptides. Involved in lifespan determination in a ubiquinone-independent manner.
messages: Component of a multi-subunit COQ enzyme complex, composed of at least COQ3, COQ4, COQ5, COQ6, COQ7 and COQ9. Interacts with ADCK4 and COQ6. Interacts with COQ9.
messages: Mitochondrion inner membrane

31033:fat-5
gene id: 31033:fat-5
uniprot id: Q5XQ38
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase type 1 family.
messages: Membrane
messages: The histidine box domains are involved in binding the catalytic metal ions.

31033:LOC105417861
gene id: 31033:LOC105417861
uniprot id: A0A3B5KHX0
names: Subcellular Location Annotation
messages: Golgi apparatus membrane
messages: Membrane

31033:LOC101079608
gene id: 31033:LOC101079608
uniprot id: H2TAG4
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. RAC subfamily.

31033:adcy7
gene id: 31033:adcy7
uniprot id: H2SYJ6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Binds 2 magnesium ions per subunit. Is also active with manganese (in vitro).
messages: Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.
messages: Membrane

31033:LOC101069301
gene id: 31033:LOC101069301
uniprot id: H2SAY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: centrosome

31033:tmem192
gene id: 31033:tmem192
uniprot id: H2UQM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM192 family.
messages: Late endosome
messages: Lysosome membrane
messages: Membrane

31033:pgpep1
gene id: 31033:pgpep1
uniprot id: H2SNP8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C15 family.
messages: Cytoplasm
messages: Removes 5-oxoproline from various penultimate amino acid residues except L-proline.

31033:LOC101069662
gene id: 31033:LOC101069662
uniprot id: H2TVH5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

31033:LOC101078539
gene id: 31033:LOC101078539
uniprot id: H2SAB8
names: Similarity
messages: Belongs to the carotenoid oxygenase family.

31033:pkm
gene id: 31033:pkm
uniprot id: Q8JJC2
names: Similarity
messages: Belongs to the pyruvate kinase family.

31033:LOC101062422
gene id: 31033:LOC101062422
uniprot id: H2VDP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM198 family.
messages: Membrane

31033:LOC101073701
gene id: 31033:LOC101073701
uniprot id: A0A674MKL7
names: Similarity
messages: Belongs to the MDFI family.

31033:LOC101067375
gene id: 31033:LOC101067375
uniprot id: H2VCE0
names: Subcellular Location Annotation
messages: Membrane

31033:LOC101067632
gene id: 31033:LOC101067632
uniprot id: H2SF35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Receptor class 5 subfamily.
messages: Membrane

31033:lpl
gene id: 31033:lpl
uniprot id: L8B319
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. Lipase family.
messages: Cell membrane
messages: Homodimer. Interacts with APOC2; the interaction activates LPL activity in the presence of lipids.
messages: Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted
messages: Tyrosine nitration after lipopolysaccharide (LPS) challenge down-regulates the lipase activity.
messages: extracellular matrix

31033:LOC101073431
gene id: 31033:LOC101073431
uniprot id: Q2PR39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

31033:dmrt2
gene id: 31033:dmrt2
uniprot id: Q4AE31
uniprot id: Q90WM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DMRT family.
messages: Nucleus

31033:LOC101073101
gene id: 31033:LOC101073101
uniprot id: H2SXW2
uniprot id: H2SXW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

31033:LOC101066857
gene id: 31033:LOC101066857
uniprot id: H2UK03
names: Subcellular Location Annotation
messages: Membrane

31033:LOC101066300
gene id: 31033:LOC101066300
uniprot id: A0A3B5K749
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

31033:prkaa1
gene id: 31033:prkaa1
uniprot id: H2VDB7
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.

31033:sdhaf3
gene id: 31033:sdhaf3
uniprot id: A0A674N3N6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I LYR family. SDHAF3 subfamily.
messages: Interacts with the iron-sulfur protein subunit within the SDH catalytic dimer.
messages: Mitochondrion matrix
messages: Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Promotes maturation of the iron-sulfur protein subunit of the SDH catalytic dimer, protecting it from the deleterious effects of oxidants. May act together with SDHAF1.

31033:jun
gene id: 31033:jun
uniprot id: Q800B4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. Jun subfamily.
messages: Nucleus

31033:nxph2
gene id: 31033:nxph2
uniprot id: H2T7P5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurexophilin family.
messages: May be signaling molecules that resemble neuropeptides.
messages: Secreted

31033:paqr6
gene id: 31033:paqr6
uniprot id: H2U5Z2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

31033:LOC101066115
gene id: 31033:LOC101066115
uniprot id: H2U5M2
names: Subcellular Location Annotation
messages: Nucleus

31033:sema6a
gene id: 31033:sema6a
uniprot id: A0A674NUS9
uniprot id: A0A674PD85
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

31033:LOC101063351
gene id: 31033:LOC101063351
uniprot id: A0A674NN85
names: Activity Regulation
names: Similarity
messages: Activated by threonine and tyrosine phosphorylation.
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.

31033:fam20c2
gene id: 31033:fam20c2
uniprot id: I7LST7
names: Similarity
messages: Belongs to the FAM20 family.

31033:LOC101070215
gene id: 31033:LOC101070215
uniprot id: Q1KL24
names: Similarity
messages: Belongs to the HIBADH-related family. 3-hydroxyisobutyrate dehydrogenase subfamily.

31033:LOC101072209
gene id: 31033:LOC101072209
uniprot id: H2SU43
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycoprotein hormones subunit beta family.
messages: Heterodimer of an alpha and a beta chain.
messages: Involved in gametogenesis and steroidogenesis.
messages: Secreted

31033:slc25a19
gene id: 31033:slc25a19
uniprot id: H2TR90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

31033:cacna2d1
gene id: 31033:cacna2d1
uniprot id: H2UCV4
names: Similarity
messages: Belongs to the calcium channel subunit alpha-2/delta family.

31033:LOC101061361
gene id: 31033:LOC101061361
uniprot id: A0A674PFR1
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

31033:ei24
gene id: 31033:ei24
uniprot id: H2SDI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EI24 family.
messages: Membrane

31033:c5h16orf72
gene id: 31033:c5h16orf72
uniprot id: A0A3B5K4Z3
names: Similarity
messages: Belongs to the TAPR1 family.

31033:LOC101076205
gene id: 31033:LOC101076205
uniprot id: H2TTW6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cyclin family. Cyclin AB subfamily.
messages: Essential for the control of the cell cycle at the G2/M (mitosis) transition.
messages: Interacts with the CDK1 protein kinase to form a serine/threonine kinase holoenzyme complex also known as maturation promoting factor (MPF). The cyclin subunit imparts substrate specificity to the complex.

31033:slitrk5
gene id: 31033:slitrk5
uniprot id: H2UGP1
names: Similarity
messages: Belongs to the SLITRK family.

31033:LOC101076056
gene id: 31033:LOC101076056
uniprot id: H2TBU8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.
messages: Membrane

31033:slc12a2
gene id: 31033:slc12a2
uniprot id: H2RWD1
uniprot id: H2RWD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC12A transporter family.
messages: Cell membrane
messages: Membrane

31033:dusp16
gene id: 31033:dusp16
uniprot id: H2S5U9
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.

31033:LOC101078946
gene id: 31033:LOC101078946
uniprot id: H2UGL2
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

31033:LOC101073228
gene id: 31033:LOC101073228
uniprot id: H2RVL8
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

31033:LOC101071448
gene id: 31033:LOC101071448
uniprot id: H2RWK2
names: Similarity
messages: Belongs to the peptidase M10A family.

31033:pigk
gene id: 31033:pigk
uniprot id: H2SUF3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase C13 family.
messages: Forms a complex with PIGT, PIGS, PIGU and GAA1.
messages: Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein.

31033:LOC101072182
gene id: 31033:LOC101072182
uniprot id: A0A3B5JW50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the securin family.
messages: Cytoplasm
messages: Nucleus

31033:LOC101069844
gene id: 31033:LOC101069844
uniprot id: H2TCH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inositol 1,4,5-trisphosphate 5-phosphatase family.
messages: Membrane

31033:LOC101075406
gene id: 31033:LOC101075406
uniprot id: H2UX75
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Aquaporins facilitate the transport of water and small neutral solutes across cell membranes.
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

31033:tecr
gene id: 31033:tecr
uniprot id: A0A3B5KAT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the steroid 5-alpha reductase family.
messages: Endoplasmic reticulum membrane
messages: Membrane

31033:LOC101062159
gene id: 31033:LOC101062159
uniprot id: A0A674NL27
names: Similarity
messages: Belongs to the yippee family.

31033:sec11a
gene id: 31033:sec11a
uniprot id: H2SEF0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S26B family.
messages: Component of the signal peptidase complex.
messages: Endoplasmic reticulum membrane
messages: Membrane

31033:egr2
gene id: 31033:egr2
uniprot id: H2RN54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EGR C2H2-type zinc-finger protein family.
messages: Nucleus

31033:e2f4
gene id: 31033:e2f4
uniprot id: H2TIK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the E2F/DP family.
messages: Nucleus

31033:LOC101067496
gene id: 31033:LOC101067496
uniprot id: H2RJL2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP Sm proteins family.
messages: Nucleus
messages: Plays a role in pre-mRNA splicing as a core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome.

31033:LOC101078303
gene id: 31033:LOC101078303
uniprot id: H2TFG7
names: Similarity
messages: Belongs to the DEAD box helicase family.

31033:wnt4
gene id: 31033:wnt4
uniprot id: A0A674MAV5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

31033:plxna3
gene id: 31033:plxna3
uniprot id: H2U7P1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the plexin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

31033:KEF89 p07
gene id: 31033:KEF89_p07
uniprot id: Q8HCV9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of 14 subunits. The complex is composed of a catalytic core of 3 subunits MT-CO1, MT-CO2 and MT-CO3, encoded in the mitochondrial DNA, and 11 supernumerary subunits COX4I, COX5A, COX5B, COX6A, COX6B, COX6C, COX7A, COX7B, COX7C, COX8 and NDUFA4, which are encoded in the nuclear genome. The complex exists as a monomer or a dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with NADH-ubiquinone oxidoreductase (complex I, CI) and ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII), resulting in different assemblies (supercomplex SCI(1)III(2)IV(1) and megacomplex MCI(2)III(2)IV(2)).
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
messages: Membrane

31033:med27
gene id: 31033:med27
uniprot id: H2VBW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 27 family.
messages: Nucleus

31033:pou4f3
gene id: 31033:pou4f3
uniprot id: H2SDR5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

31033:LOC101068696
gene id: 31033:LOC101068696
uniprot id: Q9I8E9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the parathyroid hormone family.
messages: Secreted

31033:tnmd
gene id: 31033:tnmd
uniprot id: H2TTD1
names: Similarity
messages: Belongs to the chondromodulin-1 family.

31033:rpl34
gene id: 31033:rpl34
uniprot id: A0A674MSG0
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL34 family.

31033:LOC101073605
gene id: 31033:LOC101073605
uniprot id: A0A674N6N4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

31033:os9
gene id: 31033:os9
uniprot id: A0A674NRF2
names: Subcellular Location Annotation
messages: Endoplasmic reticulum lumen

31033:LOC101068683
gene id: 31033:LOC101068683
uniprot id: H2UKE8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP dependent phosphorylation of adenosine and other related nucleoside analogs to monophosphate derivatives.
messages: Belongs to the carbohydrate kinase PfkB family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Monomer.
messages: Nucleus

31033:gprc5c
gene id: 31033:gprc5c
uniprot id: H2RZ63
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

31033:LOC101076478
gene id: 31033:LOC101076478
uniprot id: P79748
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity. Regulates the release of 5-hydroxytryptamine in the brain, and thereby affects neural activity. May also play a role in regulating the release of other neurotransmitters. May play a role in vasoconstriction (By similarity).

31033:prph
gene id: 31033:prph
uniprot id: H2VDL2
names: Similarity
messages: Belongs to the intermediate filament family.

31033:pax9
gene id: 31033:pax9
uniprot id: A0A674MJB2
names: Subcellular Location Annotation
messages: Nucleus

31033:LOC105418510
gene id: 31033:LOC105418510
uniprot id: A0A674P179
names: Similarity
messages: Belongs to the HEBP family.

31033:thbs3
gene id: 31033:thbs3
uniprot id: A0A3B5K0J4
names: Caution
names: Similarity
messages: Belongs to the thrombospondin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

31033:slc41a3
gene id: 31033:slc41a3
uniprot id: S0BBS5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Membrane

31033:sult4a1
gene id: 31033:sult4a1
uniprot id: H2THF9
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

31033:slc16a9
gene id: 31033:slc16a9
uniprot id: H2TCH1
names: Subcellular Location Annotation
messages: Membrane

31033:LOC101065642
gene id: 31033:LOC101065642
uniprot id: H2UV55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat Groucho/TLE family.
messages: Nucleus

31033:fli1
gene id: 31033:fli1
uniprot id: H2T346
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

31033:LOC101065200
gene id: 31033:LOC101065200
uniprot id: H2SEY8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ELO family. ELOVL4 subfamily.
messages: Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that specifically elongates C24:0 and C26:0 acyl-CoAs. May participate to the production of saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Oligomer.

31033:LOC101078739
gene id: 31033:LOC101078739
uniprot id: H2UXZ6
names: Function
names: Similarity
messages: Belongs to the cytochrome c oxidase subunit 6B.
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.

31033:LOC101071700
gene id: 31033:LOC101071700
uniprot id: A0A674P398
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P4HA family.
messages: Catalyzes the post-translational formation of 4-hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins.
messages: Endoplasmic reticulum lumen

31033:spc25
gene id: 31033:spc25
uniprot id: A0A3B5K4M6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.
messages: Belongs to the SPC25 family.
messages: Component of the NDC80 complex.
messages: Nucleus
messages: kinetochore

31033:LOC101066922
gene id: 31033:LOC101066922
uniprot id: Q802A4
names: Similarity
messages: Belongs to the globin family.

31033:yipf4
gene id: 31033:yipf4
uniprot id: H2RV53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YIP1 family.
messages: Membrane

31033:ngb
gene id: 31033:ngb
uniprot id: A0A674MTT6
names: Similarity
messages: Belongs to the globin family.

31033:meaf6
gene id: 31033:meaf6
uniprot id: H2TLM1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EAF6 family.
messages: Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histone H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. Component of HBO1 complexes, which specifically mediate acetylation of histone H3 at 'Lys-14' (H3K14ac), and have reduced activity toward histone H4. Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity.
messages: Component of the NuA4 histone acetyltransferase complex. Component of the hbo1 complex. Component of the moz/morf complex.
messages: kinetochore
messages: nucleolus

31033:c20h1orf52
gene id: 31033:c20h1orf52
uniprot id: H2VDE1
names: Similarity
messages: Belongs to the UPF0690 family.

31033:malt1
gene id: 31033:malt1
uniprot id: A0A674NVZ9
uniprot id: H2V1L9
names: Subcellular Location Annotation
messages: Membrane

31033:hmgcll1
gene id: 31033:hmgcll1
uniprot id: A0A674PHU3
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

31033:LOC101072202
gene id: 31033:LOC101072202
uniprot id: H2RIY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
messages: Cytoplasm

31033:LOC101076764
gene id: 31033:LOC101076764
uniprot id: A0A674NHD8
names: Similarity
messages: Belongs to the band 7/mec-2 family.

31033:gabrb3
gene id: 31033:gabrb3
uniprot id: A0A674NI38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

31033:traf3
gene id: 31033:traf3
uniprot id: H2SLR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TNF receptor-associated factor family.
messages: Cytoplasm

31033:slc49a4
gene id: 31033:slc49a4
uniprot id: H2UGN7
names: Subcellular Location Annotation
messages: Membrane

31033:svbp
gene id: 31033:svbp
uniprot id: A0A674MLI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SVBP family.
messages: Secreted
messages: cytoskeleton

31033:LOC105417509
gene id: 31033:LOC105417509
uniprot id: D4AHP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-17 family.
messages: Secreted

31033:mtap
gene id: 31033:mtap
uniprot id: A0A674MAL1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.
messages: Cytoplasm
messages: Homotrimer.
messages: Nucleus

31033:ppp1r3b
gene id: 31033:ppp1r3b
uniprot id: A0A674MD22
names: Subunit
messages: Interacts with glycogen, PPP1CC catalytic subunit of PP1 and PYGL. Associates with glycogen particles. Forms complexes with debranching enzyme, glycogen phosphorylase, glycogen synthase and phosphorylase kinase which is necessary for its regulation of PP1 activity.

31033:alkbh8
gene id: 31033:alkbh8
uniprot id: H2SXL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alkB family.
messages: Cytoplasm

31033:fer
gene id: 31033:fer
uniprot id: H2TE37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily.
messages: cytoskeleton

31033:slc52a2
gene id: 31033:slc52a2
uniprot id: H2S3Z9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the riboflavin transporter family.
messages: Cell membrane
messages: Membrane
messages: Plasma membrane transporter mediating the uptake by cells of the water soluble vitamin B2/riboflavin that plays a key role in biochemical oxidation-reduction reactions of the carbohydrate, lipid, and amino acid metabolism.

31033:LOC101071148
gene id: 31033:LOC101071148
uniprot id: H2T2U8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TGF-beta family.
messages: Secreted

31033:amt
gene id: 31033:amt
uniprot id: H2TCG8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GcvT family.
messages: Mitochondrion
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

31033:slc25a28
gene id: 31033:slc25a28
uniprot id: H2SYD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

31033:sephs1
gene id: 31033:sephs1
uniprot id: A0A3B5KKZ8
names: Function
messages: Synthesizes selenophosphate from selenide and ATP.

31033:LOC101071414
gene id: 31033:LOC101071414
uniprot id: H2TSM8
names: Subcellular Location Annotation
messages: extracellular space

31033:LOC101068171
gene id: 31033:LOC101068171
uniprot id: H2TQY3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the V-ATPase e1/e2 subunit family.
messages: Membrane
messages: Subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.

31033:lyplal1
gene id: 31033:lyplal1
uniprot id: A0A674NF37
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 2 family.

31033:pgap2
gene id: 31033:pgap2
uniprot id: H2SNG8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PGAP2 family.
messages: Involved in the lipid remodeling steps of GPI-anchor maturation. Required for stable expression of GPI-anchored proteins at the cell surface.
messages: Membrane

31033:evc2
gene id: 31033:evc2
uniprot id: Q670Z5
names: Subcellular Location Annotation
messages: Membrane
messages: cilium basal body
messages: cilium membrane

31033:LOC101069967
gene id: 31033:LOC101069967
uniprot id: H2VEB2
names: Similarity
messages: Belongs to the ATP:guanido phosphotransferase family.

31033:LOC101074874
gene id: 31033:LOC101074874
uniprot id: H2RT29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cornichon family.
messages: Membrane

31033:LOC101069529
gene id: 31033:LOC101069529
uniprot id: A0A674PD11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LAPTM4/LAPTM5 transporter family.
messages: Cell membrane
messages: Endomembrane system
messages: Endosome membrane
messages: Late endosome membrane
messages: Membrane
messages: multivesicular body lumen
messages: multivesicular body membrane

31033:LOC101062244
gene id: 31033:LOC101062244
uniprot id: A0A674NYT4
names: Subcellular Location Annotation
messages: Membrane

31033:LOC101061224
gene id: 31033:LOC101061224
uniprot id: A0A674PDV4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anoctamin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

31033:stard3
gene id: 31033:stard3
uniprot id: H2UX47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STARD3 family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Membrane

31033:slc35f6
gene id: 31033:slc35f6
uniprot id: H2SWT3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SLC35F solute transporter family.
messages: Interacts with SLC25A5.
messages: May play a role as a nucleotide-sugar transporter.
messages: Membrane
messages: Mitochondrion

31033:LOC613235
gene id: 31033:LOC613235
uniprot id: Q3SCC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-15/IL-21 family.
messages: Secreted

31033:LOC101072655
gene id: 31033:LOC101072655
uniprot id: A0A674NYZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dynactin subunits 5/6 family. Dynactin subunit 6 subfamily.
messages: cytoskeleton

31033:LOC101073250
gene id: 31033:LOC101073250
uniprot id: A0A674MEW1
names: Function
names: Similarity
messages: Belongs to the vestigial family.
messages: May act as a specific coactivator for the mammalian TEFs.

31033:LOC101062185
gene id: 31033:LOC101062185
uniprot id: A0A6D2WSK7
names: Subcellular Location Annotation
messages: Membrane

31033:med9
gene id: 31033:med9
uniprot id: A0A674NQZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 9 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

31033:dr1
gene id: 31033:dr1
uniprot id: H2UZZ9
names: Similarity
messages: Belongs to the NC2 beta/DR1 family.

31033:slc66a3
gene id: 31033:slc66a3
uniprot id: H2TQU9
names: Subcellular Location Annotation
messages: Membrane

31033:LOC101068538
gene id: 31033:LOC101068538
uniprot id: A0A3B5KMN0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

31033:LOC101066969
gene id: 31033:LOC101066969
uniprot id: A0A674PKM4
names: Similarity
messages: Belongs to the WD repeat EBI family.

31033:alg3
gene id: 31033:alg3
uniprot id: H2UHT2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Adds the first Dol-P-Man derived mannose in an alpha-1,3 linkage to Man(5)GlcNAc(2)-PP-Dol.
messages: Belongs to the glycosyltransferase 58 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

31033:glrx2
gene id: 31033:glrx2
uniprot id: H2S424
names: Function
messages: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.

31033:LOC105417634
gene id: 31033:LOC105417634
uniprot id: A0A3B5KGE6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

31033:tnfaip3
gene id: 31033:tnfaip3
uniprot id: A0A3B5JWY3
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

31033:LOC101078229
gene id: 31033:LOC101078229
uniprot id: B2GVM0
uniprot id: H2S5W6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycoprotein hormones subunit beta family.
messages: Heterodimer of an alpha and a beta chain.
messages: Involved in gametogenesis and steroidogenesis.
messages: Secreted

31033:tbx2
gene id: 31033:tbx2
uniprot id: H2T7W6
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

31033:frg1
gene id: 31033:frg1
uniprot id: O73747
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FRG1 family.
messages: Binds to mRNA in a sequence-independent manner. May play a role in regulation of pre-mRNA splicing or in the assembly of rRNA into ribosomal subunits. May be involved in mRNA transport. May be involved in epigenetic regulation of muscle differentiation through regulation of activity of the histone-lysine N-methyltransferase KMT5B.
messages: Cajal body
messages: Cytoplasm
messages: Z line
messages: nucleolus

31033:ipo5
gene id: 31033:ipo5
uniprot id: H2T0S9
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

31033:dusp1
gene id: 31033:dusp1
uniprot id: A0A3B5K6M2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
messages: Nucleus

31033:mpeg1
gene id: 31033:mpeg1
uniprot id: H2U6K3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MPEG1 family.
messages: Cytoplasmic vesicle membrane
messages: Membrane

31033:LOC101063947
gene id: 31033:LOC101063947
uniprot id: A0A3B5JU99
names: Function
names: Subcellular Location Annotation
messages: Endomembrane system
messages: Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression.

31033:LOC101075574
gene id: 31033:LOC101075574
uniprot id: H2S5M5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

31033:LOC101062905
gene id: 31033:LOC101062905
uniprot id: A0A3B5KMF1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit. The potassium ion interacts primarily with the substrate.
messages: Binds 2 magnesium ions per subunit. The magnesium ions interact primarily with the substrate.
messages: Catalyzes the formation of S-adenosylmethionine from methionine and ATP.

31033:tmem41a
gene id: 31033:tmem41a
uniprot id: H2TN18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM41 family.
messages: Membrane

31033:LOC101067021
gene id: 31033:LOC101067021
uniprot id: H2S238
names: Subcellular Location Annotation
messages: Nucleus
messages: Vesicle
messages: clathrin-coated pit
messages: clathrin-coated vesicle

31033:ddx18
gene id: 31033:ddx18
uniprot id: H2SML6
names: Similarity
messages: Belongs to the DEAD box helicase family. DDX18/HAS1 subfamily.

31033:LOC101061116
gene id: 31033:LOC101061116
uniprot id: H2T3B2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

31033:LOC101063826
gene id: 31033:LOC101063826
uniprot id: A0A674MIZ6
names: Similarity
messages: Belongs to the G-alpha family. G(q) subfamily.

31033:LOC101077176
gene id: 31033:LOC101077176
uniprot id: A0A3B5K132
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

31033:LOC101066203
gene id: 31033:LOC101066203
uniprot id: A0A674MVS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GLI C2H2-type zinc-finger protein family.
messages: Nucleus

31033:LOC101078555
gene id: 31033:LOC101078555
uniprot id: H2UV65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Cell surface
messages: Endosome
messages: Membrane

31033:dad1
gene id: 31033:dad1
uniprot id: H2RM93
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DAD/OST2 family.
messages: Component of the oligosaccharyltransferase (OST) complex.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.

31033:LOC101074288
gene id: 31033:LOC101074288
uniprot id: A0A3B5JZ98
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: High affinity receptor for melatonin. The activity of this receptor is mediated by pertussis toxin sensitive G proteins that inhibits adenylate cyclase activity.
messages: Membrane

31033:ttyh3
gene id: 31033:ttyh3
uniprot id: H2UFB5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tweety family.
messages: Cell membrane
messages: Membrane
messages: Probable chloride channel.

31033:LOC101067076
gene id: 31033:LOC101067076
uniprot id: H2SL68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

31033:LOC101072929
gene id: 31033:LOC101072929
uniprot id: Q6WNT5
names: Subcellular Location Annotation
messages: Nucleus

31033:LOC101076469
gene id: 31033:LOC101076469
uniprot id: H2SH61
names: Similarity
names: Subunit
messages: Belongs to the histone H3 family.
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

31033:LOC101070807
gene id: 31033:LOC101070807
uniprot id: A0A3B5K9I3
names: Similarity
messages: Belongs to the acylphosphatase family.

31033:smarcd1
gene id: 31033:smarcd1
uniprot id: H2VD12
names: Similarity
messages: Belongs to the SMARCD family.

31033:LOC101069073
gene id: 31033:LOC101069073
uniprot id: Q8JG01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

31033:LOC778023
gene id: 31033:LOC778023
uniprot id: H2UJ85
uniprot id: Q14DX7
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

31033:vps29
gene id: 31033:vps29
uniprot id: H2SU42
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway.
messages: Belongs to the VPS29 family.
messages: Endosome membrane

31033:tmco4
gene id: 31033:tmco4
uniprot id: A0A674MK81
names: Similarity
messages: Belongs to the TMCO4 family.

31033:LOC101078309
gene id: 31033:LOC101078309
uniprot id: A0A674NYB1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/IRO homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

31033:rfrpr
gene id: 31033:rfrpr
uniprot id: Q05KN4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for NPAF (A-18-F-amide) and NPFF (F-8-F-amide) neuropeptides, also known as morphine-modulating peptides. Can also be activated by a variety of naturally occurring or synthetic FMRF-amide like ligands. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.

31033:LOC101061965
gene id: 31033:LOC101061965
uniprot id: A0A674PNK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily. GABRA1 sub-subfamily.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

31033:LOC101069337
gene id: 31033:LOC101069337
uniprot id: H2SRW1
names: Subcellular Location Annotation
messages: Nucleus

31033:LOC101063377
gene id: 31033:LOC101063377
uniprot id: H2UDZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily.
messages: Binds to type I and type II collagen, fibronectin and TGF-beta. Forms a ternary complex with MFAP2 and ELN.
messages: May affect the rate of fibrils formation.
messages: extracellular matrix

31033:timm21
gene id: 31033:timm21
uniprot id: H2TNP6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TIM21 family.
messages: Component of the TIM23 complex.
messages: Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.
messages: Membrane
messages: Mitochondrion inner membrane
messages: Mitochondrion membrane

31033:trappc1
gene id: 31033:trappc1
uniprot id: A0A674MS07
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAPP small subunits family.
messages: Endoplasmic reticulum
messages: Part of the multisubunit transport protein particle (TRAPP) complex.
messages: cis-Golgi network

31033:adcy5
gene id: 31033:adcy5
uniprot id: A0A674N152
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Binds 2 magnesium ions per subunit. Is also active with manganese (in vitro).
messages: Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.
messages: Membrane

31033:grk4
gene id: 31033:grk4
uniprot id: A0A674NES3
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.

31033:zfpl1
gene id: 31033:zfpl1
uniprot id: H2RPJ3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZFPL1 family.
messages: Membrane
messages: Required for cis-Golgi integrity and efficient ER to Golgi transport.
messages: The B box-type and RING-type zinc fingers although degenerate play a central role in function of the protein.
messages: cis-Golgi network membrane

31033:pithd1
gene id: 31033:pithd1
uniprot id: A0A3B5JZZ0
names: Similarity
messages: Belongs to the PITHD1 family.

31033:rps3a
gene id: 31033:rps3a
uniprot id: H2UNW7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS1 family.
messages: Component of the small ribosomal subunit. Mature ribosomes consist of a small (40S) and a large (60S) subunit. The 40S subunit contains about 33 different proteins and 1 molecule of RNA (18S). The 60S subunit contains about 49 different proteins and 3 molecules of RNA (28S, 5.8S and 5S).
messages: Cytoplasm

31033:LOC101071585
gene id: 31033:LOC101071585
uniprot id: H2SY39
names: Similarity
messages: Belongs to the arrestin family.

31033:rhag
gene id: 31033:rhag
uniprot id: Q4VV03
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonium transporter (TC 2.A.49) family. Rh subfamily.
messages: Cell membrane
messages: Functions as an ammonia transporter. May play a role in the elimination of ammonia in the gill.
messages: Membrane

31033:LOC105416569
gene id: 31033:LOC105416569
uniprot id: H2V2S9
names: Similarity
messages: Belongs to the AP endonuclease 2 family.

31033:dio3a
gene id: 31033:dio3a
uniprot id: B1B571
names: Function
names: Similarity
messages: Belongs to the iodothyronine deiodinase family.
messages: Responsible for the deiodination of T4 (3,5,3',5'-tetraiodothyronine).

31033:ube2b
gene id: 31033:ube2b
uniprot id: A0A674MAI0
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

31033:LOC101062406
gene id: 31033:LOC101062406
uniprot id: H2SIJ5
names: Similarity
messages: Belongs to the glutaminyl-peptide cyclotransferase family.

31033:LOC101064194
gene id: 31033:LOC101064194
uniprot id: H2TFZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Membrane

31033:LOC101066071
gene id: 31033:LOC101066071
uniprot id: H2S2A4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Interacts with FLNA (via filamin repeat 21); increases PKA-mediated phosphorylation of FLNA.
messages: Membrane
messages: This alpha-adrenergic receptor mediates its effect through the influx of extracellular calcium.

31033:gata3
gene id: 31033:gata3
uniprot id: H2TNQ0
names: Subcellular Location Annotation
messages: Nucleus

31033:pdrg1
gene id: 31033:pdrg1
uniprot id: A0A674MGW1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the prefoldin subunit beta family.
messages: Component of the PAQosome complex which is responsible for the biogenesis of several protein complexes and which consists of R2TP complex members RUVBL1, RUVBL2, RPAP3 and PIH1D1, URI complex members PFDN2, PFDN6, PDRG1, UXT and URI1 as well as ASDURF, POLR2E and DNAAF10/WDR92.
messages: Cytoplasm
messages: May play a role in chaperone-mediated protein folding.

31033:LOC101070256
gene id: 31033:LOC101070256
uniprot id: H2U652
names: Function
messages: Regulates (in vitro) the inhibition of rhodopsin phosphorylation in a calcium-dependent manner.

31033:LOC101078774
gene id: 31033:LOC101078774
uniprot id: A0A3B5KGW3
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

31033:slc6a2
gene id: 31033:slc6a2
uniprot id: H2TS08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

31033:rce1
gene id: 31033:rce1
uniprot id: H2S941
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase U48 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

31033:emx2
gene id: 31033:emx2
uniprot id: A0A3B5K4I3
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

31033:LOC101079604
gene id: 31033:LOC101079604
uniprot id: H2SFZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

31033:LOC101069239
gene id: 31033:LOC101069239
uniprot id: A0A674PIC3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the snRNP Sm proteins family.
messages: Cytoplasm
messages: LSm subunits form a heteromer with a donut shape.
messages: P-body
messages: Probably involved with other LSm subunits in the general process of degradation of mRNAs.

31033:susd4
gene id: 31033:susd4
uniprot id: A0A3B5KKJ7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

31033:mrps18c
gene id: 31033:mrps18c
uniprot id: A0A674M9J8
names: Subcellular Location Annotation
messages: Mitochondrion

31033:LOC101080063
gene id: 31033:LOC101080063
uniprot id: H2US44
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

31033:myog
gene id: 31033:myog
uniprot id: H2RRN6
names: Subcellular Location Annotation
names: Subunit
messages: Efficient DNA binding requires dimerization with another bHLH protein.
messages: Nucleus

31033:LOC105416773
gene id: 31033:LOC105416773
uniprot id: A0A674MQT3
uniprot id: A0A674P428
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

31033:LOC101069507
gene id: 31033:LOC101069507
uniprot id: H2STT3
names: Subcellular Location Annotation
messages: Membrane

31033:fbxo31
gene id: 31033:fbxo31
uniprot id: H2RKU6
names: Similarity
names: Subunit
messages: Belongs to the FBXO31 family.
messages: Part of a SCF (SKP1-cullin-F-box) protein ligase complex.

31033:prkci
gene id: 31033:prkci
uniprot id: H2SM61
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.

31033:LOC101075584
gene id: 31033:LOC101075584
uniprot id: H2UXG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin beta chain family.
messages: Membrane

31033:pan2
gene id: 31033:pan2
uniprot id: H2UHN6
names: Activity Regulation
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase C19 family. PAN2 subfamily.
messages: Binds 2 metal cations per subunit in the catalytic exonuclease domain.
messages: Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein (PABP). PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent 5'-3' exonucleolytic degradation by XRN1.
messages: Contains a pseudo-UCH domain. This ubiquitin C-terminal hydrolase (UCH)-like or ubiquitin specific protease (USP)-like domain is predicted to be catalytically inactive because it lacks the active site catalytic triad characteristic of thiol proteases, with residues at the equivalent structural positions that are incompatible with catalysis, and it cannot bind ubiquitin. It functions as a structural scaffold for intra- and intermolecular interactions in the complex.
messages: Forms a heterotrimer with an asymmetric homodimer of the regulatory subunit PAN3 to form the poly(A)-nuclease (PAN) deadenylation complex.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus
messages: P-body
messages: Positively regulated by the regulatory subunit PAN3.
messages: The linker, or PAN3 interaction domain (PID), between the WD40 repeats and the pseudo-UCH domain mediates interaction with PAN3.

31033:scamp4
gene id: 31033:scamp4
uniprot id: H2VC83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCAMP family.
messages: Membrane

31033:mms22l
gene id: 31033:mms22l
uniprot id: H2RK09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MMS22 family. MMS22L subfamily.
messages: Chromosome
messages: Nucleus

31033:LOC101064702
gene id: 31033:LOC101064702
uniprot id: A0A3B5JUC2
names: Subcellular Location Annotation
names: Subunit
messages: Efficient DNA binding requires dimerization with another bHLH protein. Binds DNA as a heterodimer with MAX.
messages: Nucleus

31033:LOC101072853
gene id: 31033:LOC101072853
uniprot id: A0A674NAU6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

31033:sema4c
gene id: 31033:sema4c
uniprot id: A0A6D2X7Y1
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

31033:usp10
gene id: 31033:usp10
uniprot id: A0A3B5KAN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C19 family. USP10 subfamily.
messages: Cytoplasm
messages: Nucleus

31033:fgf5
gene id: 31033:fgf5
uniprot id: H2RQ78
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heparin-binding growth factors family.
messages: Interacts with FGFR1 and FGFR2. Affinity between fibroblast growth factors (FGFs) and their receptors is increased by heparan sulfate glycosaminoglycans that function as coreceptors.
messages: Plays an important role in the regulation of cell proliferation and cell differentiation. Required for normal regulation of the hair growth cycle. Functions as an inhibitor of hair elongation by promoting progression from anagen, the growth phase of the hair follicle, into catagen the apoptosis-induced regression phase.
messages: Secreted

31033:tm9sf2
gene id: 31033:tm9sf2
uniprot id: H2SS09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family.
messages: Membrane

31033:LOC101075255
gene id: 31033:LOC101075255
uniprot id: H2TMH9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.
messages: Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
messages: Mitochondrion inner membrane

31033:rplp2
gene id: 31033:rplp2
uniprot id: A0A3B5K0K7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein P1/P2 family.
messages: Heterodimer with RPLP1 at the lateral ribosomal stalk of the large ribosomal subunit.
messages: Plays an important role in the elongation step of protein synthesis.

31033:LOC101074667
gene id: 31033:LOC101074667
uniprot id: A0A674N753
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the splicing factor SR family.
messages: Nucleus

31033:LOC105416726
gene id: 31033:LOC105416726
uniprot id: A0A3B5JZH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MFAP family.
messages: extracellular matrix

31033:mlec
gene id: 31033:mlec
uniprot id: A0A3B5KN14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the malectin family.
messages: Endoplasmic reticulum membrane
messages: Membrane

31033:gtf2h3
gene id: 31033:gtf2h3
uniprot id: A0A3B5KCS4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TFB4 family.
messages: Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II. In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape. Phosphorylation of the C-terminal tail (CTD) of the largest subunit of RNA polymerase II by the kinase module CAK controls the initiation of transcription.
messages: Nucleus
messages: Part of a TFIID-containing RNA polymerase II pre-initiation complex that is composed of TBP and at least GTF2A1, GTF2A2, GTF2E1, GTF2E2, GTF2F1, GTF2H2, GTF2H3, GTF2H4, GTF2H5, GTF2B, TCEA1, ERCC2, ERCC3, TAF1, TAF2, TAF3, TAF4, TAF5, TAF6, TAF7, TAF8, TAF9, TAF10, TAF11, TAF12 and TAF13. Component of the 7-subunit TFIIH core complex composed of XPB/ERCC3, XPD/ERCC2, GTF2H1, GTF2H2, GTF2H3, GTF2H4 and GTF2H5, which is active in NER. The core complex associates with the 3-subunit CDK-activating kinase (CAK) module composed of CCNH/cyclin H, CDK7 and MNAT1 to form the 10-subunit holoenzyme (holo-TFIIH) active in transcription. Interacts with RARA; the interaction requires prior phosphorylation of RARA on 'Ser-369' which then enhances interaction of RARA with CDK7.

31033:LOC101065923
gene id: 31033:LOC101065923
uniprot id: H2VB92
names: Subcellular Location Annotation
messages: Membrane

31033:qki
gene id: 31033:qki
uniprot id: H2U0Y4
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

31033:LOC101075023
gene id: 31033:LOC101075023
uniprot id: A0A3B5KD08
names: Similarity
messages: Belongs to the Bcl-2 family.

31033:psmc3ip
gene id: 31033:psmc3ip
uniprot id: A0A674MF11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HOP2 family.
messages: Nucleus

31033:nop53
gene id: 31033:nop53
uniprot id: H2SHE3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOP53 family.
messages: May play a role in ribosome biogenesis.
messages: nucleolus
messages: nucleoplasm

31033:ahsa1
gene id: 31033:ahsa1
uniprot id: A0A3B5KA38
names: Similarity
messages: Belongs to the AHA1 family.

31033:LOC101077452
gene id: 31033:LOC101077452
uniprot id: A0A674MKQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Membrane

31033:cldn32a
gene id: 31033:cldn32a
uniprot id: Q6E5S7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

31033:LOC101066344
gene id: 31033:LOC101066344
uniprot id: A0A3B5JZL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes small subunit family.
messages: Cytoplasmic vesicle membrane
messages: Golgi apparatus
messages: clathrin-coated pit

31033:LOC497080
gene id: 31033:LOC497080
uniprot id: Q5GH52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XK family.
messages: Membrane

31033:LOC101067570
gene id: 31033:LOC101067570
uniprot id: H2SGT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 16 (GT16) protein family.
messages: Golgi apparatus membrane
messages: Membrane

31033:LOC101072878
gene id: 31033:LOC101072878
uniprot id: A0A674MPH3
names: Similarity
messages: Belongs to the SNF7 family.

31033:LOC101074969
gene id: 31033:LOC101074969
uniprot id: A0A674PN33
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

31033:dennd5a
gene id: 31033:dennd5a
uniprot id: H2V5X9
names: Caution
names: Similarity
messages: Belongs to the RAB6IP1 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

31033:LOC101064208
gene id: 31033:LOC101064208
uniprot id: H2U9I1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

31033:atp6v0a1
gene id: 31033:atp6v0a1
uniprot id: H2UPV5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.
messages: Membrane

31033:LOC101069919
gene id: 31033:LOC101069919
uniprot id: H2U5Y9
names: Subcellular Location Annotation
messages: Nucleus

31033:masp2
gene id: 31033:masp2
uniprot id: A0A3B5K7B7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

31033:mrpl37
gene id: 31033:mrpl37
uniprot id: H2SG93
names: Subcellular Location Annotation
messages: Mitochondrion

31033:LOC101073544
gene id: 31033:LOC101073544
uniprot id: H2TSB7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family. Bicoid subfamily.
messages: Nucleus
messages: Plays a critical role in eye formation by regulating the initial specification of retinal cells and/or their subsequent proliferation.
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

31033:smc2
gene id: 31033:smc2
uniprot id: Q802S1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMC family. SMC2 subfamily.
messages: Chromosome
messages: Nucleus

31033:LOC101064911
gene id: 31033:LOC101064911
uniprot id: A0A3B5KTD4
names: Similarity
messages: Belongs to the cornifelin family.

31033:rps19bp1
gene id: 31033:rps19bp1
uniprot id: A0A3B5K7H3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AROS family.
messages: nucleolus

31033:LOC101079316
gene id: 31033:LOC101079316
uniprot id: A0A3B5KJU1
names: Subcellular Location Annotation
messages: Membrane
messages: Mitochondrion membrane

31033:srrd
gene id: 31033:srrd
uniprot id: H2UXX1
names: Similarity
messages: Belongs to the SRR1 family.

31033:LOC101061223
gene id: 31033:LOC101061223
uniprot id: H2T1B7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tissue factor family.
messages: Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The [TF:VIIa] complex activates factors IX or X by specific limited proteolysis. TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade.
messages: Interacts with HSPE; the interaction, inhibited by heparin, promotes the generation of activated factor X and activates coagulation in the presence of activated factor VII.

31033:LOC101069009
gene id: 31033:LOC101069009
uniprot id: A0A674P821
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAVIN family.
messages: caveola
messages: sarcomere

31033:iah1
gene id: 31033:iah1
uniprot id: A0A674P2I5
names: Function
names: Similarity
messages: Belongs to the 'GDSL' lipolytic enzyme family. IAH1 subfamily.
messages: Probable lipase.

31033:rbks
gene id: 31033:rbks
uniprot id: H2SRH7
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Nucleus
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

31033:sft2d3
gene id: 31033:sft2d3
uniprot id: A0A3B5JZX3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SFT2 family.
messages: May be involved in fusion of retrograde transport vesicles derived from an endocytic compartment with the Golgi complex.
messages: Membrane

31033:ttc39b
gene id: 31033:ttc39b
uniprot id: H2TG08
names: Similarity
messages: Belongs to the TTC39 family.

31033:cers5
gene id: 31033:cers5
uniprot id: A0A674MB01
names: Function
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

31033:LOC101069879
gene id: 31033:LOC101069879
uniprot id: A0A674NGH8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ORM family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Negative regulator of sphingolipid synthesis.

31033:LOC101078860
gene id: 31033:LOC101078860
uniprot id: H2U7C7
names: Similarity
messages: Belongs to the TAPR1 family.

31033:mindy1
gene id: 31033:mindy1
uniprot id: A0A3B5KDM2
names: Function
names: Similarity
messages: Belongs to the MINDY deubiquitinase family. FAM63 subfamily.
messages: Hydrolase that can specifically remove 'Lys-48'-linked conjugated ubiquitin from proteins. Has exodeubiquitinase activity and has a preference for long polyubiquitin chains. May play a regulatory role at the level of protein turnover.

31033:LOC101077676
gene id: 31033:LOC101077676
uniprot id: A0A674PG78
names: Subcellular Location Annotation
messages: Membrane

31033:nlgn2
gene id: 31033:nlgn2
uniprot id: D2X2G8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type-B carboxylesterase/lipase family.
messages: Cell membrane
messages: Membrane

31033:LOC101062077
gene id: 31033:LOC101062077
uniprot id: H2UR44
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate.
messages: Belongs to the sulfotransferase 6 family.
messages: Membrane

31033:LOC101063396
gene id: 31033:LOC101063396
uniprot id: A0A674MFV7
names: Similarity
messages: Belongs to the syntaxin family.

31033:serpine3
gene id: 31033:serpine3
uniprot id: H2UBC7
names: Similarity
messages: Belongs to the serpin family.

31033:tiprl
gene id: 31033:tiprl
uniprot id: H2T0T6
names: Similarity
messages: Belongs to the TIP41 family.

31033:fam92a
gene id: 31033:fam92a
uniprot id: A0A674PK98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CIBAR family.
messages: centriole

31033:LOC101063188
gene id: 31033:LOC101063188
uniprot id: H2V1R4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

31033:LOC101064317
gene id: 31033:LOC101064317
uniprot id: A0A674P414
names: Subcellular Location Annotation
messages: Membrane

31033:LOC105417819
gene id: 31033:LOC105417819
uniprot id: A0A674NI89
uniprot id: A0A674NZN3
names: Similarity
messages: Belongs to the CDI family.

31033:krtcap3
gene id: 31033:krtcap3
uniprot id: H2SGK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM54 family.
messages: Membrane

31033:LOC101079369
gene id: 31033:LOC101079369
uniprot id: H2U5V8
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Associates with the cytoplasmic CCR4-NOT deadenylase complex to trigger ARE-containing mRNA deadenylation and decay processes.
messages: Cytoplasm
messages: Nucleus
messages: Zinc-finger RNA-binding protein that destabilizes several cytoplasmic AU-rich element (ARE)-containing mRNA transcripts by promoting their poly(A) tail removal or deadenylation, and hence provide a mechanism for attenuating protein synthesis. Acts as a 3'-untranslated region (UTR) ARE mRNA-binding adapter protein to communicate signaling events to the mRNA decay machinery. Functions by recruiting the CCR4-NOT deadenylase complex and probably other components of the cytoplasmic RNA decay machinery to the bound ARE-containing mRNAs, and hence promotes ARE-mediated mRNA deadenylation and decay processes. Binds to 3'-UTR ARE of numerous mRNAs.

31033:nek8
gene id: 31033:nek8
uniprot id: H2SLW6
names: Similarity
messages: Belongs to the protein kinase superfamily. NEK Ser/Thr protein kinase family. NIMA subfamily.

31033:nrtn
gene id: 31033:nrtn
uniprot id: A0A674PIK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TGF-beta family. GDNF subfamily.
messages: Secreted

31033:LOC101064253
gene id: 31033:LOC101064253
uniprot id: Q1KL13
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family. Deformed subfamily.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

31033:LOC101075674
gene id: 31033:LOC101075674
uniprot id: H2SY23
names: Similarity
messages: Belongs to the dickkopf family.

31033:lgi3
gene id: 31033:lgi3
uniprot id: Q1EGK0
names: Subcellular Location Annotation
messages: Secreted

31033:LOC101062194
gene id: 31033:LOC101062194
uniprot id: H2UJF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

31033:LOC101073015
gene id: 31033:LOC101073015
uniprot id: A0A674NPI8
names: Subcellular Location Annotation
messages: Membrane

31033:LOC101076304
gene id: 31033:LOC101076304
uniprot id: H2UYN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Membrane
messages: cis-Golgi network membrane

31033:odf2
gene id: 31033:odf2
uniprot id: H2SSA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ODF2 family.
messages: centrosome

31033:neu3
gene id: 31033:neu3
uniprot id: A7TVK4
names: Similarity
messages: Belongs to the glycosyl hydrolase 33 family.

31033:LOC101068057
gene id: 31033:LOC101068057
uniprot id: A1KXU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transcription factor STAT family.
messages: Cytoplasm
messages: Nucleus

31033:arpc2
gene id: 31033:arpc2
uniprot id: H2UIU6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ARPC2 family.
messages: Cell projection
messages: Component of the Arp2/3 complex.
messages: Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.
messages: cytoskeleton

31033:myo1b
gene id: 31033:myo1b
uniprot id: H2SCL2
uniprot id: H2SCL3
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

31033:LOC101078390
gene id: 31033:LOC101078390
uniprot id: H2S8S8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dynein light chain family.
messages: cytoskeleton

31033:LOC101066282
gene id: 31033:LOC101066282
uniprot id: H2TR44
names: Similarity
messages: Belongs to the ANP32 family.

31033:LOC101079683
gene id: 31033:LOC101079683
uniprot id: A0A674PDQ8
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

31033:LOC101072541
gene id: 31033:LOC101072541
uniprot id: A0A674PGK4
uniprot id: Q1KKY1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

31033:lsm4
gene id: 31033:lsm4
uniprot id: A0A3B5K599
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the snRNP Sm proteins family.
messages: Binds specifically to the 3'-terminal U-tract of U6 snRNA.
messages: LSm subunits form a heteromer with a doughnut shape.
messages: Nucleus

31033:LOC101063456
gene id: 31033:LOC101063456
uniprot id: A0A3B5KGI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAPRE family.
messages: cytoskeleton

31033:emc4
gene id: 31033:emc4
uniprot id: H2SJH5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EMC4 family.
messages: Component of the ER membrane protein complex (EMC).
messages: Endoplasmic reticulum membrane
messages: Membrane

31033:LOC101078264
gene id: 31033:LOC101078264
uniprot id: H2UXH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM205 family.
messages: Membrane

31033:ddb2
gene id: 31033:ddb2
uniprot id: H2UPZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat DDB2/WDR76 family.
messages: Nucleus

31033:slc9a5
gene id: 31033:slc9a5
uniprot id: A0A674NBX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Membrane

31033:scf
gene id: 31033:scf
uniprot id: C1PGH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCF family.
messages: Cytoplasm
messages: Secreted
messages: filopodium
messages: lamellipodium

31033:eif3l
gene id: 31033:eif3l
uniprot id: H2V812
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit L family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
messages: Cytoplasm

31033:LOC101070683
gene id: 31033:LOC101070683
uniprot id: A0A3B5K586
names: Subcellular Location Annotation
messages: Membrane

31033:LOC115246478
gene id: 31033:LOC115246478
uniprot id: H2SUE7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycoprotein hormones subunit alpha family.
messages: Heterodimer of an alpha and a beta chain.
messages: Secreted

31033:mapk1
gene id: 31033:mapk1
uniprot id: A0A674PAT2
names: Activity Regulation
names: Similarity
messages: Activated by threonine and tyrosine phosphorylation.
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.

31033:slc9a3r1
gene id: 31033:slc9a3r1
uniprot id: A0A674PAK1
names: Function
names: Subcellular Location Annotation
messages: Endomembrane system
messages: Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression.
messages: filopodium
messages: microvillus
messages: ruffle

31033:LOC101069895
gene id: 31033:LOC101069895
uniprot id: H2VEI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XRCC4-XLF family. XRCC4 subfamily.
messages: Nucleus

31033:LOC101075259
gene id: 31033:LOC101075259
uniprot id: H2VCR3
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

31033:LOC105416747
gene id: 31033:LOC105416747
uniprot id: H2SPC2
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

31033:LOC101079930
gene id: 31033:LOC101079930
uniprot id: A0A674PME4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complexin/synaphin family.
messages: Synapse

31033:LOC101065654
gene id: 31033:LOC101065654
uniprot id: A0A3B5KMX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 47 family.
messages: Endoplasmic reticulum membrane

31033:cpe
gene id: 31033:cpe
uniprot id: H2UTP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M14 family.
messages: Membrane
messages: secretory vesicle membrane

31033:spcs3
gene id: 31033:spcs3
uniprot id: H2SJ52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPCS3 family.
messages: Endoplasmic reticulum membrane

31033:LOC101079985
gene id: 31033:LOC101079985
uniprot id: A0A674N7J9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the JUPITER family.
messages: Cytoplasm
messages: Nucleus

31033:LOC101061221
gene id: 31033:LOC101061221
uniprot id: A0A674PFB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family.
messages: Membrane

31033:LOC101072736
gene id: 31033:LOC101072736
uniprot id: A0A3B5JV66
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Cell membrane
messages: Lipid droplet

31033:LOC101071494
gene id: 31033:LOC101071494
uniprot id: H2U4I2
names: Similarity
messages: Belongs to the YY transcription factor family.

31033:tubg1
gene id: 31033:tubg1
uniprot id: H2ULC6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tubulin family.
messages: Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome.
messages: centrosome

31033:aff3
gene id: 31033:aff3
uniprot id: A0A674MVP3
names: Similarity
messages: Belongs to the AF4 family.

31033:LOC101068717
gene id: 31033:LOC101068717
uniprot id: A0A3B5KIQ6
names: Similarity
messages: Belongs to the VHL family.

31033:ybey
gene id: 31033:ybey
uniprot id: A0A674NE25
names: Similarity
messages: Belongs to the endoribonuclease YbeY family.

31033:pla2g12a
gene id: 31033:pla2g12a
uniprot id: A0A3B5KPP2
names: Subcellular Location Annotation
messages: Secreted

31033:LOC101073614
gene id: 31033:LOC101073614
uniprot id: A0A674N6W6
names: Subcellular Location Annotation
messages: Cytoplasm

31033:cacnb4
gene id: 31033:cacnb4
uniprot id: B6IDF1
uniprot id: B6IDF2
names: Similarity
messages: Belongs to the calcium channel beta subunit family.

31033:LOC101075532
gene id: 31033:LOC101075532
uniprot id: H2SW92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PUR DNA-binding protein family.
messages: Nucleus

31033:LOC101072937
gene id: 31033:LOC101072937
uniprot id: Q7T077
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

31033:sike1
gene id: 31033:sike1
uniprot id: A0A674M9R9
names: Similarity
messages: Belongs to the SIKE family.

31033:fmnl2
gene id: 31033:fmnl2
uniprot id: A0A674P8H8
names: Similarity
messages: Belongs to the formin homology family.

31033:mrpl40
gene id: 31033:mrpl40
uniprot id: A0A3B5JY34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL40 family.
messages: Mitochondrion

31033:LOC105417859
gene id: 31033:LOC105417859
uniprot id: A0A674MRE8
names: Subcellular Location Annotation
messages: Nucleus

31033:cldn31
gene id: 31033:cldn31
uniprot id: Q6E5T6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

31033:vps26c
gene id: 31033:vps26c
uniprot id: H2SWQ0
names: Similarity
messages: Belongs to the VPS26 family.

31033:LOC101068343
gene id: 31033:LOC101068343
uniprot id: A0A674MZB0
names: Subcellular Location Annotation
messages: Membrane

31033:cxcl12
gene id: 31033:cxcl12
uniprot id: A0A674NL48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine alpha (chemokine CxC) family.
messages: Secreted

31033:rpl4
gene id: 31033:rpl4
uniprot id: H2UKK2
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.

31033:ifitm5
gene id: 31033:ifitm5
uniprot id: A0A674NIG8
names: Similarity
messages: Belongs to the CD225/Dispanin family.

31033:nop58
gene id: 31033:nop58
uniprot id: A0A674P7F9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOP5/NOP56 family.
messages: nucleolus

31033:LOC101074139
gene id: 31033:LOC101074139
uniprot id: H2UL04
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

31033:map2k5
gene id: 31033:map2k5
uniprot id: H2V1U6
names: Similarity
messages: Belongs to the protein kinase superfamily.

31033:ssr1
gene id: 31033:ssr1
uniprot id: A0A674PNE6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP-alpha family.
messages: Endoplasmic reticulum membrane
messages: Heterotetramer of TRAP-alpha, TRAP-beta, TRAP-delta and TRAP-gamma.
messages: Membrane
messages: Shows a remarkable charge distribution with the N-terminus being highly negatively charged, and the cytoplasmic C-terminus positively charged.
messages: TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins. May be involved in the recycling of the translocation apparatus after completion of the translocation process or may function as a membrane-bound chaperone facilitating folding of translocated proteins.

31033:ik
gene id: 31033:ik
uniprot id: A0A674MZY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RED family.
messages: Nucleus

31033:LOC101065506
gene id: 31033:LOC101065506
uniprot id: A0A3B5K5U2
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family. Chitinase class II subfamily.

31033:LOC101072996
gene id: 31033:LOC101072996
uniprot id: A0A3B5K3J6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

31033:grhl1
gene id: 31033:grhl1
uniprot id: H2UCZ9
names: Subcellular Location Annotation
messages: Nucleus

31033:LOC101061321
gene id: 31033:LOC101061321
uniprot id: H2U9B0
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.

31033:oca2
gene id: 31033:oca2
uniprot id: H2TDY4
names: Subcellular Location Annotation
messages: Membrane

31033:LOC101071645
gene id: 31033:LOC101071645
uniprot id: H2TQW6
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.

31033:LOC101063597
gene id: 31033:LOC101063597
uniprot id: H2UHH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CALHM family.
messages: Membrane

31033:ca7
gene id: 31033:ca7
uniprot id: A0A510ADZ2
uniprot id: H2V4P5
names: Function
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

31033:fignl1
gene id: 31033:fignl1
uniprot id: H2V8M7
names: Similarity
messages: Belongs to the AAA ATPase family.

31033:LOC101063363
gene id: 31033:LOC101063363
uniprot id: H2ST55
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Cell membrane
messages: Interacts with SLC4A4.
messages: Membrane
messages: Reversible hydration of carbon dioxide.

31033:eif2s1
gene id: 31033:eif2s1
uniprot id: H2V9Z7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eIF-2-alpha family.
messages: Stress granule

31033:scamp2
gene id: 31033:scamp2
uniprot id: H2UVV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCAMP family.
messages: Membrane

31033:itpr2
gene id: 31033:itpr2
uniprot id: H2SPX2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the InsP3 receptor family.
messages: Endoplasmic reticulum membrane
messages: Homotetramer.
messages: Membrane
messages: Receptor for inositol 1,4,5-trisphosphate, a second messenger that mediates the release of intracellular calcium.
messages: The receptor contains a calcium channel in its C-terminal extremity. Its large N-terminal cytoplasmic region has the ligand-binding site in the N-terminus and modulatory sites in the middle portion immediately upstream of the channel region.

31033:LOC101069763
gene id: 31033:LOC101069763
uniprot id: H2V773
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

31033:rnf7
gene id: 31033:rnf7
uniprot id: H2SUJ8
names: Similarity
messages: Belongs to the RING-box family.

31033:LOC101061626
gene id: 31033:LOC101061626
uniprot id: H2UPJ6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.
messages: Cytoplasm
messages: Hydrolyzes ATP, and can also hydrolyze GTP with lower efficiency. Has lower affinity for GTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Nucleus
messages: nucleolus

31033:LOC101077059
gene id: 31033:LOC101077059
uniprot id: Q800B5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. Jun subfamily.
messages: Nucleus

31033:LOC101061711
gene id: 31033:LOC101061711
uniprot id: O13074
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family. Deformed subfamily.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

31033:LOC101068592
gene id: 31033:LOC101068592
uniprot id: A0A3B5KDY6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the distal-less homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

31033:LOC101074303
gene id: 31033:LOC101074303
uniprot id: H2U3I7
names: Similarity
messages: Belongs to the TGF-beta family.

31033:KEF89 p08
gene id: 31033:KEF89_p08
uniprot id: Q8HCW0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase A chain family.
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Membrane
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Key component of the proton channel; it may play a direct role in the translocation of protons across the membrane.
messages: Mitochondrion inner membrane

31033:bola2b
gene id: 31033:bola2b
uniprot id: A0A674MT95
names: Similarity
messages: Belongs to the BolA/IbaG family.

31033:LOC101067694
gene id: 31033:LOC101067694
uniprot id: A0A3B5JZF7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERGIC family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Golgi apparatus membrane
messages: Plays a role in transport between endoplasmic reticulum and Golgi.

31033:lhx9
gene id: 31033:lhx9
uniprot id: A0A674NWY6
uniprot id: A0A674P750
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

31033:septin8
gene id: 31033:septin8
uniprot id: H2SRE6
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.

31033:mkrn2
gene id: 31033:mkrn2
uniprot id: Q5NU13
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Although the makorin-type Cys-His region lacks the final His residue, the following Asp residue may be able to coordinate Zn(2+).
messages: Cytoplasm
messages: E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins (By similarity). Inhibits neurogenesis and axis formation during embryonic development by modulating the phosphatidylinositol 3-kinase (PI3K) pathway. Acts downstream of PI3K and akt1 to up-regulate gsk3b mRNA expression.
messages: Nucleus

31033:pus7
gene id: 31033:pus7
uniprot id: A0A3B5KQM1
names: Similarity
messages: Belongs to the pseudouridine synthase TruD family.

31033:LOC101072218
gene id: 31033:LOC101072218
uniprot id: H2S048
names: Similarity
messages: Belongs to the threonine aldolase family.

31033:LOC101062165
gene id: 31033:LOC101062165
uniprot id: H2TWV0
names: Similarity
messages: Belongs to the pellino family.

31033:barx1
gene id: 31033:barx1
uniprot id: H2SHF7
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

31033:evx2
gene id: 31033:evx2
uniprot id: Q1KKT3
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

31033:LOC105417541
gene id: 31033:LOC105417541
uniprot id: A0A3B5K930
names: Similarity
messages: Belongs to the serpin family.

31033:clcn3
gene id: 31033:clcn3
uniprot id: A0A674P3I0
uniprot id: A0A674P7R8
uniprot id: H2S682
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel (TC 2.A.49) family. ClC-3/CLCN3 subfamily.
messages: Cell membrane
messages: Early endosome membrane
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane
messages: Membrane

31033:pgls
gene id: 31033:pgls
uniprot id: H2UJ91
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

31033:ndufs7
gene id: 31033:ndufs7
uniprot id: H2S712
names: Similarity
messages: Belongs to the complex I 20 kDa subunit family.

31033:LOC101075888
gene id: 31033:LOC101075888
uniprot id: H2U5R3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sideroflexin family.
messages: Membrane
messages: Mitochondrion membrane

31033:LOC101069563
gene id: 31033:LOC101069563
uniprot id: H2SG42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Membrane

31033:tfcp2
gene id: 31033:tfcp2
uniprot id: H2UMA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the grh/CP2 family. CP2 subfamily.
messages: Nucleus

31033:emp2
gene id: 31033:emp2
uniprot id: A0A3B5KB43
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the PMP-22/EMP/MP20 family.
messages: Cell membrane
messages: Golgi apparatus membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Membrane raft
messages: Nucleus
messages: perinuclear region

31033:LOC101074625
gene id: 31033:LOC101074625
uniprot id: A0A674MVD4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the F-actin-capping protein alpha subunit family.
messages: F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
messages: Heterodimer of an alpha and a beta subunit.

31033:LOC101069875
gene id: 31033:LOC101069875
uniprot id: A0A674MU59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Endoplasmic reticulum membrane
messages: Membrane

31033:gdf11
gene id: 31033:gdf11
uniprot id: H2VDF5
names: Similarity
messages: Belongs to the TGF-beta family.

31033:cercam
gene id: 31033:cercam
uniprot id: H2T9Q6
names: Similarity
messages: Belongs to the glycosyltransferase 25 family.

31033:f2
gene id: 31033:f2
uniprot id: Q804W7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing.
messages: extracellular space

31033:st6gal2
gene id: 31033:st6gal2
uniprot id: Q5QQ37
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Golgi stack membrane
messages: Transfers sialic acid from the donor of substrate CMP-sialic acid to galactose containing acceptor substrates.

31033:LOC101062685
gene id: 31033:LOC101062685
uniprot id: A0A674MIH3
uniprot id: A0A674MXC7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOTCH family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Nucleus

31033:LOC101073575
gene id: 31033:LOC101073575
uniprot id: H2V3V0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.
messages: Cytoplasm
messages: Responds to activation by environmental stress and pro-inflammatory cytokines by phosphorylating a number of transcription factors, and thus regulates transcriptional activity.

31033:dusp10
gene id: 31033:dusp10
uniprot id: A0A3B5KKU8
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.

31033:adgrf1
gene id: 31033:adgrf1
uniprot id: Q08KN2
names: Subcellular Location Annotation
messages: Membrane

31033:LOC101069312
gene id: 31033:LOC101069312
uniprot id: H2UN25
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

31033:tac1
gene id: 31033:tac1
uniprot id: A0A674NMH2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tachykinin family.
messages: Secreted
messages: Tachykinins are active peptides which excite neurons, evoke behavioral responses, are potent vasodilators and secretagogues, and contract (directly or indirectly) many smooth muscles.

31033:stx7
gene id: 31033:stx7
uniprot id: H2UBE9
names: Similarity
messages: Belongs to the syntaxin family.

31033:LOC101067834
gene id: 31033:LOC101067834
uniprot id: H2SIP5
names: Similarity
messages: Belongs to the protein kinase superfamily.

31033:LOC101066503
gene id: 31033:LOC101066503
uniprot id: A0A674NW16
names: Similarity
messages: Belongs to the calcitonin family.

31033:vbp1
gene id: 31033:vbp1
uniprot id: H2S6C4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prefoldin subunit alpha family.
messages: Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.
messages: Heterohexamer of two PFD-alpha type and four PFD-beta type subunits.

31033:LOC101062351
gene id: 31033:LOC101062351
uniprot id: H2U6H2
names: Function
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

31033:LOC101075526
gene id: 31033:LOC101075526
uniprot id: A0A674N3A0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat LIS1/nudF family.
messages: Can self-associate. Component of the cytosolic PAF-AH (I) heterotetrameric enzyme, which is composed of PAFAH1B1 (beta), PAFAH1B2 (alpha2) and PAFAH1B3 (alpha1) subunits. The catalytic activity of the enzyme resides in the alpha1 (PAFAH1B3) and alpha2 (PAFAH1B2) subunits, whereas the beta subunit (PAFAH1B1) has regulatory activity. Trimer formation is not essential for the catalytic activity (By similarity). Interacts with dynein, dynactin, nde1 and ndel1.
messages: Can self-associate. Interacts with dynein, dynactin, NDE1 and NDEL1.
messages: Dimerization mediated by the LisH domain may be required to activate dynein.
messages: Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. May be required for proliferation of neuronal precursors and neuronal migration.
messages: centrosome
messages: cytoskeleton

31033:mab21l2
gene id: 31033:mab21l2
uniprot id: H2T290
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mab-21 family.
messages: Cytoplasm
messages: Nucleus

31033:dda1
gene id: 31033:dda1
uniprot id: A0A674NQW2
names: Similarity
messages: Belongs to the DDA1 family.

31033:kpnb1
gene id: 31033:kpnb1
uniprot id: H2RMC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the importin beta family. Importin beta-1 subfamily.
messages: Cytoplasm

31033:LOC101066865
gene id: 31033:LOC101066865
uniprot id: H2RZW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDNFR family.
messages: Cell membrane
messages: Membrane

31033:LOC101071080
gene id: 31033:LOC101071080
uniprot id: A0A674NY09
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane

31033:hoxa3
gene id: 31033:hoxa3
uniprot id: Q1KL12
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

31033:LOC101067620
gene id: 31033:LOC101067620
uniprot id: A0A674PC09
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I 51 kDa subunit family.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.
messages: Mitochondrion inner membrane

31033:LOC101063736
gene id: 31033:LOC101063736
uniprot id: A0A674NX23
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNAP family.
messages: Membrane
messages: Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus.

31033:LOC101066134
gene id: 31033:LOC101066134
uniprot id: A0A3B5JUD8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OST3/OST6 family.
messages: Cell membrane
messages: Endoplasmic reticulum membrane
messages: Membrane

31033:fzd6
gene id: 31033:fzd6
uniprot id: H2SXD9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the G-protein coupled receptor Fz/Smo family.
messages: Cell membrane
messages: Cell surface
messages: Cytoplasmic vesicle membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

31033:blmh
gene id: 31033:blmh
uniprot id: H2TBG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C1 family.
messages: Cytoplasm

31033:lmbr1
gene id: 31033:lmbr1
uniprot id: H2TMI6
names: Similarity
messages: Belongs to the LIMR family.

31033:LOC101069587
gene id: 31033:LOC101069587
uniprot id: H2T679
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPSB family.
messages: Cytoplasm

31033:ube3d
gene id: 31033:ube3d
uniprot id: A0A674P602
names: Function
messages: E3 ubiquitin-protein ligase which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, and transfers it to substrates, generally promoting their degradation by the proteasome.

31033:adssl1
gene id: 31033:adssl1
uniprot id: A0A674N4C5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.
messages: Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis.

31033:ncoa2
gene id: 31033:ncoa2
uniprot id: A0A674PAS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SRC/p160 nuclear receptor coactivator family.
messages: Nucleus

31033:LOC101073058
gene id: 31033:LOC101073058
uniprot id: A0A674P6Y4
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3 GTPase family.

31033:dusp7
gene id: 31033:dusp7
uniprot id: A0A674NIM1
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.

31033:mrpl47
gene id: 31033:mrpl47
uniprot id: H2V7B6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal ribosomal protein uL29 family.
messages: Mitochondrion

31033:polr2c
gene id: 31033:polr2c
uniprot id: H2SFB7
names: Similarity
messages: Belongs to the archaeal Rpo3/eukaryotic RPB3 RNA polymerase subunit family.

31033:cltrn
gene id: 31033:cltrn
uniprot id: H2U8B9
names: Subcellular Location Annotation
messages: Membrane

31033:LOC101075383
gene id: 31033:LOC101075383
uniprot id: H2SW62
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

31033:LOC101061669
gene id: 31033:LOC101061669
uniprot id: H2V8W8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM59 family.
messages: Golgi apparatus membrane
messages: Membrane

31033:atg5
gene id: 31033:atg5
uniprot id: H2RL06
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATG5 family.
messages: Conjugated with ATG12.
messages: Involved in autophagic vesicle formation. Conjugation with ATG12, through a ubiquitin-like conjugating system involving ATG7 as an E1-like activating enzyme and ATG10 as an E2-like conjugating enzyme, is essential for its function. The ATG12-ATG5 conjugate acts as an E3-like enzyme which is required for lipidation of ATG8 family proteins and their association to the vesicle membranes. Involved in mitochondrial quality control after oxidative damage, and in subsequent cellular longevity. Plays a critical role in multiple aspects of lymphocyte development and is essential for both B and T lymphocyte survival and proliferation. Required for optimal processing and presentation of antigens for MHC II. Involved in the maintenance of axon morphology and membrane structures, as well as in normal adipocyte differentiation. Promotes primary ciliogenesis through removal of OFD1 from centriolar satellites and degradation of IFT20 via the autophagic pathway.
messages: May play an important role in the apoptotic process, possibly within the modified cytoskeleton. Its expression is a relatively late event in the apoptotic process, occurring downstream of caspase activity. Plays a crucial role in IFN-gamma-induced autophagic cell death by interacting with FADD.
messages: Preautophagosomal structure membrane

31033:fam168a
gene id: 31033:fam168a
uniprot id: H2SWN8
names: Similarity
messages: Belongs to the FAM168 family.

31033:srp9
gene id: 31033:srp9
uniprot id: A0A674NVN9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SRP9 family.
messages: Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER). SRP9 together with SRP14 and the Alu portion of the SRP RNA, constitutes the elongation arrest domain of SRP. The complex of SRP9 and SRP14 is required for SRP RNA binding.
messages: Cytoplasm

31033:zranb1
gene id: 31033:zranb1
uniprot id: A0A3B5KCA5
names: Similarity
messages: Belongs to the peptidase C64 family.

31033:LOC101067841
gene id: 31033:LOC101067841
uniprot id: H2T1C7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Cell membrane
messages: Membrane

31033:nol12
gene id: 31033:nol12
uniprot id: A0A674MUB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRP17 family.
messages: nucleolus

31033:gadd45gip1
gene id: 31033:gadd45gip1
uniprot id: H2UE61
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a negative regulator of G1 to S cell cycle phase progression by inhibiting cyclin-dependent kinases. Inhibitory effects are additive with GADD45 proteins but occurs also in the absence of GADD45 proteins. Acts as a repressor of the orphan nuclear receptor NR4A1 by inhibiting AB domain-mediated transcriptional activity. May be involved in the hormone-mediated regulation of NR4A1 transcriptional activity. May play a role in mitochondrial protein synthesis.
messages: Belongs to the mitochondrion-specific ribosomal protein mL64 family.
messages: Mitochondrion
messages: Nucleus

31033:LOC101069556
gene id: 31033:LOC101069556
uniprot id: H2TTH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Endoplasmic reticulum membrane

31033:LOC101075421
gene id: 31033:LOC101075421
uniprot id: H2RZ86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

31033:LOC101063630
gene id: 31033:LOC101063630
uniprot id: A0A3B5K4H9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HMGB family.
messages: Chromosome

31033:LOC101073008
gene id: 31033:LOC101073008
uniprot id: A0A3B5K051
names: Similarity
messages: Belongs to the RASGRP family.

31033:gnb1
gene id: 31033:gnb1
uniprot id: A0A674PKN5
names: Similarity
messages: Belongs to the WD repeat G protein beta family.

31033:fen1
gene id: 31033:fen1
uniprot id: H2U529
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XPG/RAD2 endonuclease family. FEN1 subfamily.
messages: Binds 2 magnesium ions per subunit. They probably participate in the reaction catalyzed by the enzyme. May bind an additional third magnesium ion after substrate binding.
messages: Interacts with PCNA. Three molecules of fen1 bind to one PCNA trimer with each molecule binding to one PCNA monomer. PCNA stimulates the nuclease activity without altering cleavage specificity.
messages: Mitochondrion
messages: Phosphorylated. Phosphorylation upon DNA damage induces relocalization to the nuclear plasma.
messages: Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site-terminated flap. Acts as a genome stabilization factor that prevents flaps from equilibrating into structures that lead to duplications and deletions. Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA, and exhibits RNase H activity. Also involved in replication and repair of rDNA and in repairing mitochondrial DNA.
messages: nucleolus
messages: nucleoplasm

31033:LOC101076947
gene id: 31033:LOC101076947
uniprot id: A0A674PDQ0
names: Similarity
messages: Belongs to the GADD45 family.

31033:LOC101080114
gene id: 31033:LOC101080114
uniprot id: A0A3B5KBQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/PBX homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

31033:suclg1
gene id: 31033:suclg1
uniprot id: A0A674NRV2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterodimer of an alpha and a beta subunit. Different beta subunits determine nucleotide specificity. Together with the ATP-specific beta subunit SUCLA2, forms an ADP-forming succinyl-CoA synthetase (A-SCS). Together with the GTP-specific beta subunit SUCLG2 forms a GDP-forming succinyl-CoA synthetase (G-SCS).
messages: Mitochondrion
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits.

31033:got2
gene id: 31033:got2
uniprot id: H2VAC0
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.
messages: In eukaryotes there are cytoplasmic, mitochondrial and chloroplastic isozymes.

31033:myo1e
gene id: 31033:myo1e
uniprot id: H2V897
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

31033:LOC101072547
gene id: 31033:LOC101072547
uniprot id: A0A674NXE4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate.
messages: Belongs to the sulfotransferase 6 family.
messages: Membrane

31033:LOC101079928
gene id: 31033:LOC101079928
uniprot id: H2RR36
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

31033:slc10a1
gene id: 31033:slc10a1
uniprot id: H2UL33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bile acid:sodium symporter (BASS) (TC 2.A.28) family.
messages: Membrane

31033:LOC101069574
gene id: 31033:LOC101069574
uniprot id: A0A3B5K2S0
names: Similarity
messages: Belongs to the universal ribosomal protein uL16 family.

31033:LOC101072748
gene id: 31033:LOC101072748
uniprot id: A0A674P7L7
names: Similarity
messages: Belongs to the AFG1 ATPase family.

31033:LOC101072248
gene id: 31033:LOC101072248
uniprot id: H2U403
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel CLIC family.
messages: Cytoplasm
messages: Members of this family may change from a globular, soluble state to a state where the N-terminal domain is inserted into the membrane and functions as chloride channel. A conformation change of the N-terminal domain is thought to expose hydrophobic surfaces that trigger membrane insertion.
messages: Membrane

31033:LOC101075371
gene id: 31033:LOC101075371
uniprot id: A0A3B5KHV1
names: Subcellular Location Annotation
messages: Membrane

31033:LOC101062877
gene id: 31033:LOC101062877
uniprot id: H2SG89
names: Activity Regulation
names: Domain
names: Function
names: Subcellular Location Annotation
messages: Endosome membrane
messages: GAP activity stimulated by phosphatidylinositol 4,5-bisphosphate (PIP2) and phosphatidic acid.
messages: GTPase-activating protein for the ADP ribosylation factor family.
messages: PH domain binds phospholipids including phosphatidic acid, phosphatidylinositol 3-phosphate, phosphatidylinositol 3,5-bisphosphate (PIP2) and phosphatidylinositol 3,4,5-trisphosphate (PIP3). May mediate protein binding to PIP2 or PIP3 containing membranes.
messages: The BAR domain mediates homodimerization, it can neither bind membrane nor impart curvature, but instead requires the neighboring PH domain to achieve these functions.

31033:LOC777946
gene id: 31033:LOC777946
uniprot id: A0A3B5KC23
uniprot id: Q5XQ39
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase type 1 family.
messages: Membrane
messages: The histidine box domains are involved in binding the catalytic metal ions.

31033:pdhb
gene id: 31033:pdhb
uniprot id: H2RZ13
names: Function
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and thereby links the glycolytic pathway to the tricarboxylic cycle.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.

31033:smad9
gene id: 31033:smad9
uniprot id: H2RRM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dwarfin/SMAD family.
messages: Cytoplasm
messages: Nucleus

31033:LOC101079435
gene id: 31033:LOC101079435
uniprot id: A0A674N212
uniprot id: H2S3K0
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.

31033:LOC101064624
gene id: 31033:LOC101064624
uniprot id: H2RYX7
names: Similarity
messages: Belongs to the globin family.

31033:rab39b
gene id: 31033:rab39b
uniprot id: A0A3B5KPK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Cell membrane
messages: Membrane

31033:LOC101074421
gene id: 31033:LOC101074421
uniprot id: H2RPQ9
names: Similarity
messages: Belongs to the PRPH2/ROM1 family.

31033:LOC101065288
gene id: 31033:LOC101065288
uniprot id: A0A674MJM2
names: Subcellular Location Annotation
messages: Endoplasmic reticulum
messages: Golgi apparatus

31033:cpn1
gene id: 31033:cpn1
uniprot id: H2U9J6
names: Similarity
messages: Belongs to the peptidase M14 family.

31033:ubald2
gene id: 31033:ubald2
uniprot id: A0A674N867
names: Similarity
messages: Belongs to the UBALD family.

31033:LOC101068299
gene id: 31033:LOC101068299
uniprot id: A0A674MDY7
names: Similarity
messages: Belongs to the S-100 family.

31033:gtf2f2
gene id: 31033:gtf2f2
uniprot id: A0A3B5JUK5
uniprot id: A0A3B5JZM8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFIIF beta subunit family.
messages: Nucleus
messages: TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB.

31033:agt
gene id: 31033:agt
uniprot id: Q6IMN9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the serpin family.
messages: Essential component of the renin-angiotensin system (RAS), a potent regulator of blood pressure, body fluid and electrolyte homeostasis.
messages: Secreted
messages: Stimulates aldosterone release.

31033:itpkb
gene id: 31033:itpkb
uniprot id: H2UH00
names: Similarity
messages: Belongs to the inositol phosphokinase (IPK) family.

31033:ncapg
gene id: 31033:ncapg
uniprot id: H2UCZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CND3 (condensin subunit 3) family.
messages: Chromosome

31033:slc25a46
gene id: 31033:slc25a46
uniprot id: A0A674NUZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion outer membrane

31033:LOC101064326
gene id: 31033:LOC101064326
uniprot id: H2UET2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CYRI family.
messages: Membrane

31033:rap2b
gene id: 31033:rap2b
uniprot id: H2UFE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Ras family.
messages: Endosome membrane
messages: Recycling endosome membrane

31033:cnnm1
gene id: 31033:cnnm1
uniprot id: A0A097ZIH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ACDP family.
messages: Membrane

31033:asz1
gene id: 31033:asz1
uniprot id: Q9I8E3
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Interacts with DDX4, PIWIL1, RANBP9 and TDRD1.

31033:LOC101070221
gene id: 31033:LOC101070221
uniprot id: H2SC76
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mo25 family.
messages: Component of a complex that binds and activates STK11/LKB1. In the complex, required to stabilize the interaction between CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta) and STK11/LKB1.
messages: Component of a trimeric complex composed of STK11/LKB1, STRAD (STRADA or STRADB) and CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta): the complex tethers STK11/LKB1 in the cytoplasm and stimulates its catalytic activity.

31033:LOC101068778
gene id: 31033:LOC101068778
uniprot id: A0A3B5KB22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. JAK subfamily.
messages: Endomembrane system
messages: Nucleus

31033:LOC101080086
gene id: 31033:LOC101080086
uniprot id: A0A3B5K6W6
names: Similarity
messages: Belongs to the tumor necrosis factor family.

31033:tamm41
gene id: 31033:tamm41
uniprot id: H2S0L1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAM41 family.
messages: Catalyzes the conversion of phosphatidic acid (PA) to CDP-diacylglycerol (CDP-DAG), an essential intermediate in the synthesis of phosphatidylglycerol, cardiolipin and phosphatidylinositol.
messages: Mitochondrion inner membrane

31033:ptcd2
gene id: 31033:ptcd2
uniprot id: H2VD74
names: Similarity
messages: Belongs to the PTCD2 family.

31033:msl3
gene id: 31033:msl3
uniprot id: H2U4T6
names: Subcellular Location Annotation
messages: Nucleus

31033:prkg2
gene id: 31033:prkg2
uniprot id: A0A674PQD6
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cGMP subfamily.

31033:tpm4
gene id: 31033:tpm4
uniprot id: Q805C5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tropomyosin family.
messages: cytoskeleton

31033:LOC101079430
gene id: 31033:LOC101079430
uniprot id: H2T510
names: Subcellular Location Annotation
messages: Membrane

31033:LOC101074415
gene id: 31033:LOC101074415
uniprot id: H2V1R1
names: Subcellular Location Annotation
messages: Nucleus

31033:LOC101077477
gene id: 31033:LOC101077477
uniprot id: A0A674MRM1
names: Similarity
messages: Belongs to the VEFS (VRN2-EMF2-FIS2-SU(Z)12) family.

31033:LOC101064338
gene id: 31033:LOC101064338
uniprot id: A0A3B5KV91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P33MONOX family.
messages: Cytoplasm

31033:rnf8
gene id: 31033:rnf8
uniprot id: H2SP55
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CHFR family.
messages: Belongs to the RNF8 family.
messages: E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53BP1 and BRCA1 ionizing radiation-induced foci (IRIF). H2A ubiquitination also mediates the ATM-dependent transcriptional silencing at regions flanking DSBs in cis, a mechanism to avoid collision between transcription and repair intermediates. Also catalyzes the formation of 'Lys-48'-linked polyubiquitin chains, leading to degradation of substrate proteins. In addition to its function in damage signaling, also plays a role in higher-order chromatin structure by mediating extensive chromatin decondensation.
messages: Homodimer. Forms a E2-E3 ubiquitin ligase complex composed of the RNF8 homodimer and a E2 heterodimer of UBE2N and UBE2V2.
messages: Nucleus
messages: The FHA domain specifically recognizes and binds ATM-phosphorylated MDC1.

31033:galr1
gene id: 31033:galr1
uniprot id: H2V675
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

31033:keap1
gene id: 31033:keap1
uniprot id: H2S9L0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KEAP1 family.
messages: Cytoplasm
messages: Nucleus

31033:LOC101070414
gene id: 31033:LOC101070414
uniprot id: A0A674PNA8
names: Activity Regulation
names: Similarity
names: Subcellular Location Annotation
messages: Activated by DAG and phorbol esters.
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PKD subfamily.
messages: Cytoplasm
messages: Membrane

31033:fabp1
gene id: 31033:fabp1
uniprot id: H2USJ2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
messages: Binds free fatty acids and their coenzyme A derivatives, bilirubin, and some other small molecules in the cytoplasm. May be involved in intracellular lipid transport.
messages: Cytoplasm
messages: Forms a beta-barrel structure that accommodates hydrophobic ligands in its interior.

31033:LOC101067374
gene id: 31033:LOC101067374
uniprot id: H2TDA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM229 family.
messages: Membrane

31033:slc14a1
gene id: 31033:slc14a1
uniprot id: Q5W8V6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urea transporter family.
messages: Cell membrane
messages: Membrane

31033:plpp3
gene id: 31033:plpp3
uniprot id: A0A3B5K387
uniprot id: H2UY52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

31033:LOC101076595
gene id: 31033:LOC101076595
uniprot id: H2U5V3
names: Similarity
messages: Belongs to the peptidase C2 family.

31033:maco1
gene id: 31033:maco1
uniprot id: Q2TLY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the macoilin family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Nucleus membrane
messages: Rough endoplasmic reticulum membrane

31033:qrsl1
gene id: 31033:qrsl1
uniprot id: A0A674PHJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Mitochondrion
messages: Subunit of the heterotrimeric GatCAB amidotransferase (AdT) complex, composed of A (QRSL1), B (GATB) and C (GATC) subunits.

31033:tmed10
gene id: 31033:tmed10
uniprot id: A0A674MHS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Endoplasmic reticulum membrane
messages: Membrane

31033:chfr
gene id: 31033:chfr
uniprot id: H2U8D4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CHFR family.
messages: PML body

31033:stambp
gene id: 31033:stambp
uniprot id: H2UP12
names: Similarity
messages: Belongs to the peptidase M67C family.

31033:med11
gene id: 31033:med11
uniprot id: A0A3B5KBV4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 11 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

31033:LOC101066348
gene id: 31033:LOC101066348
uniprot id: H2T805
names: Similarity
messages: Belongs to the OSBP family.

31033:LOC101074340
gene id: 31033:LOC101074340
uniprot id: H2RJC4
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

31033:c6h5orf30
gene id: 31033:c6h5orf30
uniprot id: H2SVL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UNC119-binding protein family.
messages: Cytoplasm
messages: cilium

31033:shbg
gene id: 31033:shbg
uniprot id: H2U4E8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

31033:anxa10
gene id: 31033:anxa10
uniprot id: A0A674NH77
names: Domain
names: Similarity
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Belongs to the annexin family.

31033:gcdh
gene id: 31033:gcdh
uniprot id: H2T7M2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

31033:dok6
gene id: 31033:dok6
uniprot id: H2SGD0
names: Similarity
messages: Belongs to the DOK family. Type B subfamily.

31033:LOC101066661
gene id: 31033:LOC101066661
uniprot id: A0A3B5K775
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

31033:cyhr1
gene id: 31033:cyhr1
uniprot id: H2UAT3
names: Similarity
messages: Belongs to the ZFTRAF1 family.

31033:tle3
gene id: 31033:tle3
uniprot id: Q3LFR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat Groucho/TLE family.
messages: Nucleus

31033:cldn3a
gene id: 31033:cldn3a
uniprot id: Q6E5R0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

31033:LOC101073142
gene id: 31033:LOC101073142
uniprot id: H2TEN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

31033:cldn3c
gene id: 31033:cldn3c
uniprot id: Q6E5S0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

31033:bcdin3d
gene id: 31033:bcdin3d
uniprot id: H2VCX5
names: Similarity
messages: Belongs to the methyltransferase superfamily.

31033:LOC101070858
gene id: 31033:LOC101070858
uniprot id: H2VAV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the splicing factor SR family.
messages: Nucleus

31033:gna12
gene id: 31033:gna12
uniprot id: H2TWM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-alpha family. G(12) subfamily.
messages: Membrane

31033:LOC101064034
gene id: 31033:LOC101064034
uniprot id: H2UUQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Membrane

31033:exosc2
gene id: 31033:exosc2
uniprot id: A0A674PLK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRP4 family.
messages: Cytoplasm

31033:dntt
gene id: 31033:dntt
uniprot id: Q75U67
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-X family.
messages: Nucleus
messages: Template-independent DNA polymerase which catalyzes the random addition of deoxynucleoside 5'-triphosphate to the 3'-end of a DNA initiator.

31033:ghitm
gene id: 31033:ghitm
uniprot id: H2TXC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

31033:dbndd1
gene id: 31033:dbndd1
uniprot id: H2VBI9
names: Similarity
messages: Belongs to the dysbindin family.

31033:polr2e
gene id: 31033:polr2e
uniprot id: H2VBT9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal Rpo5/eukaryotic RPB5 RNA polymerase subunit family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non-coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. Pol II is the central component of the basal RNA polymerase II transcription machinery. Pols are composed of mobile elements that move relative to each other. In Pol II, POLR2E/RPB5 is part of the lower jaw surrounding the central large cleft and thought to grab the incoming DNA template. Seems to be the major component in this process.
messages: Nucleus

31033:gadd45a
gene id: 31033:gadd45a
uniprot id: A0A674NVV9
names: Similarity
messages: Belongs to the GADD45 family.

31033:vps26b
gene id: 31033:vps26b
uniprot id: A0A674P1R0
names: Similarity
messages: Belongs to the VPS26 family.

31033:LOC101076332
gene id: 31033:LOC101076332
uniprot id: A0A674MR92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NPY family.
messages: Secreted

31033:hdac4
gene id: 31033:hdac4
uniprot id: A0A674MXL2
uniprot id: A0A674N687
uniprot id: A0A674PFX0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone deacetylase family. HD type 2 subfamily.
messages: Nucleus
messages: Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.

31033:bcl7b
gene id: 31033:bcl7b
uniprot id: A0A3B5JZI1
names: Similarity
messages: Belongs to the BCL7 family.

31033:LOC101066235
gene id: 31033:LOC101066235
uniprot id: Q6WNU2
names: Subcellular Location Annotation
messages: Nucleus

31033:LOC101070634
gene id: 31033:LOC101070634
uniprot id: A0A3B5K7B0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. Suvar3-9 subfamily.
messages: Nucleus
messages: centromere

31033:LOC101078882
gene id: 31033:LOC101078882
uniprot id: H2SJI9
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein P1/P2 family.
messages: Plays an important role in the elongation step of protein synthesis.

31033:vegfa
gene id: 31033:vegfa
uniprot id: A0A674MWJ2
names: Similarity
messages: Belongs to the PDGF/VEGF growth factor family.

31033:LOC778000
gene id: 31033:LOC778000
uniprot id: Q14DX6
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

31033:rtca
gene id: 31033:rtca
uniprot id: H2TBR3
names: Function
names: Similarity
messages: Belongs to the RNA 3'-terminal cyclase family. Type 1 subfamily.
messages: Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing.

31033:LOC101063003
gene id: 31033:LOC101063003
uniprot id: A0A3B5KI97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.
messages: Nucleus

31033:drd4
gene id: 31033:drd4
uniprot id: H2UQY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

31033:LOC101068305
gene id: 31033:LOC101068305
uniprot id: A0A674MEC3
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

31033:LOC101065589
gene id: 31033:LOC101065589
uniprot id: H2SEX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

31033:LOC101066672
gene id: 31033:LOC101066672
uniprot id: A0A674MK41
names: Similarity
messages: Belongs to the protein kinase superfamily.

31033:LOC101067333
gene id: 31033:LOC101067333
uniprot id: Q1KL06
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c family.
messages: Binds 1 heme c group covalently per subunit.
messages: Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain (By similarity).
messages: Mitochondrion intermembrane space

31033:LOC101061085
gene id: 31033:LOC101061085
uniprot id: H2RM13
names: Similarity
messages: Belongs to the phosphatase 2A regulatory subunit B family.

31033:dolpp1
gene id: 31033:dolpp1
uniprot id: H2VCR2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dolichyldiphosphatase family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Required for efficient N-glycosylation. Necessary for maintaining optimal levels of dolichol-linked oligosaccharides. Hydrolyzes dolichyl pyrophosphate at a very high rate and dolichyl monophosphate at a much lower rate. Does not act on phosphatidate.

31033:LOC101074452
gene id: 31033:LOC101074452
uniprot id: A0A674NX12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mago nashi family.
messages: Nucleus

31033:rln3
gene id: 31033:rln3
uniprot id: Q0GY50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the insulin family.
messages: Secreted

31033:tspan6
gene id: 31033:tspan6
uniprot id: H2U084
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

31033:rh30-like
gene id: 31033:rh30-like
uniprot id: Q7T3R3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonium transporter (TC 2.A.49) family. Rh subfamily.
messages: Cell membrane
messages: Functions as an ammonia transporter. May play a role in the elimination of ammonia in the gill.
messages: Membrane

31033:lmnb2
gene id: 31033:lmnb2
uniprot id: H2SCX9
names: Similarity
messages: Belongs to the intermediate filament family.

31033:LOC101074871
gene id: 31033:LOC101074871
uniprot id: A0A674MC65
names: Similarity
messages: Belongs to the DDIT4 family.

31033:tmem184a
gene id: 31033:tmem184a
uniprot id: A0A3B5KMN6
names: Subcellular Location Annotation
messages: Membrane

31033:LOC101069036
gene id: 31033:LOC101069036
uniprot id: H2V7U9
names: Subcellular Location Annotation
messages: Membrane

31033:arhgdia
gene id: 31033:arhgdia
uniprot id: H2T9Q1
names: Similarity
messages: Belongs to the Rho GDI family.

31033:LOC619283
gene id: 31033:LOC619283
uniprot id: H2THY3
uniprot id: Q3LU31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synuclein family.
messages: Membrane
messages: Nucleus
messages: Secreted
messages: Synapse

31033:LOC101073669
gene id: 31033:LOC101073669
uniprot id: A0A3B5K2H7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adaptor complexes small subunit family.
messages: COPI-coated vesicle membrane
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.
messages: The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex.

31033:s1pr1
gene id: 31033:s1pr1
uniprot id: H2TJ49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

31033:sart1
gene id: 31033:sart1
uniprot id: Q9DF75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNU66/SART1 family.
messages: Nucleus

31033:LOC101063710
gene id: 31033:LOC101063710
uniprot id: A0A3B5K781
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

31033:LOC101064989
gene id: 31033:LOC101064989
uniprot id: A0A674P3U5
names: Similarity
messages: Belongs to the RBR family.

31033:LOC101063953
gene id: 31033:LOC101063953
uniprot id: A0A3B5K643
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

31033:six6
gene id: 31033:six6
uniprot id: H2TPS1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SIX/Sine oculis homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

31033:psmb2
gene id: 31033:psmb2
uniprot id: A0A3B5KPC3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome complex.
messages: Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
messages: Cytoplasm
messages: Nucleus

31033:LOC101066279
gene id: 31033:LOC101066279
uniprot id: H2TQJ8
names: Function
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.
messages: Plays a role in valine and pyrimidine metabolism. Binds fatty acyl-CoA.

31033:tfap2d
gene id: 31033:tfap2d
uniprot id: H2RPI3
names: Similarity
messages: Belongs to the AP-2 family.

31033:LOC101078283
gene id: 31033:LOC101078283
uniprot id: H2RPT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NIPA family.
messages: Membrane

31033:dipk1b
gene id: 31033:dipk1b
uniprot id: H2SWL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DIPK family.
messages: Endoplasmic reticulum membrane

31033:kxd1
gene id: 31033:kxd1
uniprot id: A0A3B5K8G3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KXD1 family.
messages: Lysosome membrane

31033:LOC101071673
gene id: 31033:LOC101071673
uniprot id: A0A674P2R2
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

31033:fam20c3
gene id: 31033:fam20c3
uniprot id: A0A6D2WBR0
names: Similarity
messages: Belongs to the FAM20 family.

31033:LOC101071061
gene id: 31033:LOC101071061
uniprot id: A0A674NWX8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIA subfamily.
messages: Catalyzes the hydrolysis of ATP coupled with the transport of calcium.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Sarcoplasmic reticulum membrane

31033:pdpr
gene id: 31033:pdpr
uniprot id: A0A674MYH2
names: Similarity
messages: Belongs to the GcvT family.

31033:LOC101068984
gene id: 31033:LOC101068984
uniprot id: A0A6I8PJ16
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

31033:LOC101070134
gene id: 31033:LOC101070134
uniprot id: A0A3B5K686
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

31033:LOC101077403
gene id: 31033:LOC101077403
uniprot id: A0A3B5K812
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPC7 RNA polymerase subunit family.
messages: Nucleus

31033:sf3b4
gene id: 31033:sf3b4
uniprot id: H2SE87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SF3B4 family.
messages: Nucleus

31033:LOC101065275
gene id: 31033:LOC101065275
uniprot id: A0A674PR57
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eIF-5A family.
messages: Endoplasmic reticulum membrane
messages: eIF-5A seems to be the only eukaryotic protein to have a hypusine residue which is a post-translational modification of a lysine by the addition of a butylamino group.
messages: mRNA-binding protein involved in translation elongation. Has an important function at the level of mRNA turnover, probably acting downstream of decapping. Critical for the efficient synthesis of peptide bonds between consecutive proline residues. Can resolve ribosomal stalling caused by consecutive prolines during translation. Involved in actin dynamics and cell cycle progression, mRNA decay and probably in a pathway involved in stress response and maintenance of cell wall integrity. Functions as a regulator of apoptosis.

31033:LOC101068319
gene id: 31033:LOC101068319
uniprot id: H2U541
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCM family.
messages: Nucleus

31033:anapc2
gene id: 31033:anapc2
uniprot id: H2S6S1
names: Similarity
messages: Belongs to the cullin family.

31033:pacsin1
gene id: 31033:pacsin1
uniprot id: H2TTB2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Cytoplasmic vesicle membrane
messages: Membrane
messages: cytosol
messages: ruffle membrane
messages: synaptosome

31033:LOC101064651
gene id: 31033:LOC101064651
uniprot id: A0A3B5KKG3
uniprot id: H2UNM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

31033:KEF89 p01
gene id: 31033:KEF89_p01
uniprot id: Q8HCV3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome b family.
messages: Binds 2 heme groups non-covalently.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
messages: Membrane
messages: Mitochondrion inner membrane

31033:hsf1
gene id: 31033:hsf1
uniprot id: H2RK44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSF family.
messages: Nucleus

31033:arf3
gene id: 31033:arf3
uniprot id: P61207
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: GTP-binding protein involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus.
messages: Golgi apparatus

31033:mettl14
gene id: 31033:mettl14
uniprot id: H2RLC5
names: Similarity
messages: Belongs to the MT-A70-like family.

31033:rpl23
gene id: 31033:rpl23
uniprot id: A0A674N2U7
names: Similarity
messages: Belongs to the universal ribosomal protein uL14 family.

31033:copa
gene id: 31033:copa
uniprot id: H2TLX7
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Membrane
messages: Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins; the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors.

31033:specc1l
gene id: 31033:specc1l
uniprot id: Q2KN94
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytospin-A family.
messages: Involved in cytokinesis and spindle organization. May play a role in actin cytoskeleton organization and microtubule stabilization and hence required for proper cell adhesion and migration (By similarity).
messages: May interact with both microtubules and actin cytoskeleton.
messages: cytoskeleton
messages: gap junction
messages: spindle

31033:fam214b
gene id: 31033:fam214b
uniprot id: H2SBG3
names: Similarity
messages: Belongs to the FAM214 family.

31033:LOC105417099
gene id: 31033:LOC105417099
uniprot id: A0A674NJ17
names: Similarity
messages: Belongs to the CD225/Dispanin family.

31033:mitf
gene id: 31033:mitf
uniprot id: A0A674MP27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MiT/TFE family.
messages: Nucleus

31033:LOC101075726
gene id: 31033:LOC101075726
uniprot id: A0A674MZ54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family.
messages: Membrane

31033:nmbr
gene id: 31033:nmbr
uniprot id: H2UA47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

31033:stx5
gene id: 31033:stx5
uniprot id: H2U8A7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the syntaxin family.
messages: Membrane

31033:mpp1
gene id: 31033:mpp1
uniprot id: O57431
names: Similarity
messages: Belongs to the MAGUK family.

31033:LOC101069147
gene id: 31033:LOC101069147
uniprot id: A0A674ND84
names: Similarity
messages: Belongs to the SF3A3 family.

31033:mrpl49
gene id: 31033:mrpl49
uniprot id: H2RY40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL49 family.
messages: Mitochondrion

31033:rab27a
gene id: 31033:rab27a
uniprot id: H2V9S5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Endosome
messages: Late endosome
messages: Membrane

31033:alg9
gene id: 31033:alg9
uniprot id: H2V3V8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 22 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

31033:hoxd9
gene id: 31033:hoxd9
uniprot id: Q1KKS9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

31033:LOC101070349
gene id: 31033:LOC101070349
uniprot id: A0A674PEW8
names: Similarity
messages: Belongs to the protein kinase superfamily.

31033:LOC101066013
gene id: 31033:LOC101066013
uniprot id: H2VAI5
names: Subcellular Location Annotation
messages: extracellular space

31033:LOC101074111
gene id: 31033:LOC101074111
uniprot id: H2SSX9
names: Subcellular Location Annotation
messages: Membrane

31033:plk4
gene id: 31033:plk4
uniprot id: H2T1P6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDC5/Polo subfamily.
messages: centriole

31033:LOC101078211
gene id: 31033:LOC101078211
uniprot id: A0A3B5KRU7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

31033:aip
gene id: 31033:aip
uniprot id: H2SAS9
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Interacts with RET in the pituitary gland; this interaction prevents the formation of the AIP-survivin complex.
messages: May play a positive role in AHR-mediated (aromatic hydrocarbon receptor) signaling, possibly by influencing its receptivity for ligand and/or its nuclear targeting.

31033:slc17a6
gene id: 31033:slc17a6
uniprot id: A0A674NVQ5
names: Subcellular Location Annotation
messages: Membrane

31033:LOC101070876
gene id: 31033:LOC101070876
uniprot id: H2TC50
names: Similarity
messages: Belongs to the CNKSR family.

31033:LOC101062073
gene id: 31033:LOC101062073
uniprot id: A0A3B5KPJ3
names: Function
names: Similarity
messages: Belongs to the parvalbumin family.
messages: In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions.

31033:acat1
gene id: 31033:acat1
uniprot id: H2S0Z3
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

31033:LOC101066992
gene id: 31033:LOC101066992
uniprot id: A0A674PGV2
names: Subcellular Location Annotation
messages: extracellular space

31033:LOC101067287
gene id: 31033:LOC101067287
uniprot id: A0A674P2X4
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.

31033:LOC101064861
gene id: 31033:LOC101064861
uniprot id: H2UGY0
names: Subcellular Location Annotation
messages: Nucleus

31033:LOC101063301
gene id: 31033:LOC101063301
uniprot id: A0A3B5JV90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

31033:tas1r2
gene id: 31033:tas1r2
uniprot id: Q2MHK1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

31033:yipf6
gene id: 31033:yipf6
uniprot id: A0A674N3R8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YIP1 family.
messages: Membrane

31033:kbtbd8
gene id: 31033:kbtbd8
uniprot id: A0A674MSJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KBTBD8 family.
messages: Golgi apparatus
messages: spindle

31033:hsd17b1
gene id: 31033:hsd17b1
uniprot id: H2UPG6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Cytoplasm
messages: Favors the reduction of estrogens and androgens. Uses preferentially NADH.

31033:thg1l
gene id: 31033:thg1l
uniprot id: H2TIL1
names: Cofactor
names: Function
names: Similarity
messages: Adds a GMP to the 5'-end of tRNA(His) after transcription and RNase P cleavage.
messages: Belongs to the tRNA(His) guanylyltransferase family.
messages: Binds 2 magnesium ions per subunit.

31033:aldh1a2
gene id: 31033:aldh1a2
uniprot id: Q402D1
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

31033:LOC101063388
gene id: 31033:LOC101063388
uniprot id: H2SPM1
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

31033:LOC101073405
gene id: 31033:LOC101073405
uniprot id: H2UR30
names: Similarity
messages: Belongs to the vasopressin/oxytocin family.

31033:gabra2
gene id: 31033:gabra2
uniprot id: A0A674NQY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily. GABRA2 sub-subfamily.
messages: Cell membrane
messages: Cytoplasmic vesicle membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane
messages: dendrite

31033:acvr1
gene id: 31033:acvr1
uniprot id: H2SXS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane

31033:b3galt6
gene id: 31033:b3galt6
uniprot id: Q256Y8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

31033:LOC101062063
gene id: 31033:LOC101062063
uniprot id: H2SC19
names: Cofactor
names: Function
names: Subunit
messages: Binds 1 zinc ion per subunit.
messages: Homotetramer.
messages: Involved in the regulation of homocysteine metabolism.

31033:pde4b
gene id: 31033:pde4b
uniprot id: A0A674PR18
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family. PDE4 subfamily.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

31033:LOC101067373
gene id: 31033:LOC101067373
uniprot id: A0A3B5K4W3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

31033:LOC101067344
gene id: 31033:LOC101067344
uniprot id: A0A674MJU1
names: Similarity
messages: Belongs to the pellino family.

31033:ndufa2
gene id: 31033:ndufa2
uniprot id: A0A3B5KM42
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA2 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

31033:itga8
gene id: 31033:itga8
uniprot id: H2U873
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

31033:aida
gene id: 31033:aida
uniprot id: H2SQF6
names: Similarity
messages: Belongs to the AIDA family.

31033:pdss2
gene id: 31033:pdss2
uniprot id: A0A3B5KAC7
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

31033:LOC101075267
gene id: 31033:LOC101075267
uniprot id: A0A3B5K4F0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

31033:LOC101075152
gene id: 31033:LOC101075152
uniprot id: A0A3B5K420
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

31033:slc22a2
gene id: 31033:slc22a2
uniprot id: H2TCR6
names: Similarity
messages: Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family.

31033:LOC101073257
gene id: 31033:LOC101073257
uniprot id: H2SCF7
names: Similarity
messages: Belongs to the prickle / espinas / testin family.

31033:LOC101077558
gene id: 31033:LOC101077558
uniprot id: A0A674MTZ1
names: Cofactor
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS27 family.
messages: Binds 1 zinc ion per subunit.

31033:meis2
gene id: 31033:meis2
uniprot id: A0A674NP10
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/MEIS homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

31033:rpl35a
gene id: 31033:rpl35a
uniprot id: H2S7F0
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL33 family.

31033:ykt6
gene id: 31033:ykt6
uniprot id: A0A3B5K6P9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Cytoplasmic vesicle membrane
messages: Golgi apparatus membrane
messages: Membrane
messages: Vesicular soluble NSF attachment protein receptor (v-SNARE) mediating vesicle docking and fusion to a specific acceptor cellular compartment. Functions in endoplasmic reticulum to Golgi transport; as part of a SNARE complex composed of GOSR1, GOSR2 and STX5. Functions in early/recycling endosome to TGN transport; as part of a SNARE complex composed of BET1L, GOSR1 and STX5. Has a S-palmitoyl transferase activity.

31033:psme1
gene id: 31033:psme1
uniprot id: H2SK17
names: Similarity
messages: Belongs to the PA28 family.

31033:vgll3
gene id: 31033:vgll3
uniprot id: H2SBW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vestigial family.
messages: Nucleus

31033:LOC101066144
gene id: 31033:LOC101066144
uniprot id: A0A3B5KHZ2
names: Similarity
messages: Belongs to the HEBP family.

31033:LOC101074350
gene id: 31033:LOC101074350
uniprot id: A0A674PKX6
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.

31033:LOC101072780
gene id: 31033:LOC101072780
uniprot id: H2V2Q8
names: Cofactor
names: Similarity
messages: Belongs to the 5'(3')-deoxyribonucleotidase family.
messages: Binds 1 Mg(2+) ion per subunit.

31033:LOC101066309
gene id: 31033:LOC101066309
uniprot id: H2SEP1
names: Subcellular Location Annotation
messages: Membrane

31033:LOC101062892
gene id: 31033:LOC101062892
uniprot id: A0A674MY89
names: Similarity
messages: Belongs to the MAX family.

31033:LOC101065476
gene id: 31033:LOC101065476
uniprot id: A0A3B5KKU3
names: Similarity
messages: Belongs to the PP2C family.

31033:srp14
gene id: 31033:srp14
uniprot id: H2U9W4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SRP14 family.
messages: Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER). SRP9 together with SRP14 and the Alu portion of the SRP RNA, constitutes the elongation arrest domain of SRP. The complex of SRP9 and SRP14 is required for SRP RNA binding.
messages: Cytoplasm
messages: Heterodimer with SRP9; binds RNA as heterodimer. Component of a signal recognition particle (SRP) complex that consists of a 7SL RNA molecule of 300 nucleotides and six protein subunits: SRP72, SRP68, SRP54, SRP19, SRP14 and SRP9.

31033:vip
gene id: 31033:vip
uniprot id: A0A674NC38
uniprot id: A8DPE0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glucagon family.
messages: Secreted
messages: VIP causes vasodilation, lowers arterial blood pressure, stimulates myocardial contractility, increases glycogenolysis and relaxes the smooth muscle of trachea, stomach and gall bladder.

31033:irf2bp1
gene id: 31033:irf2bp1
uniprot id: H2RIR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IRF2BP family.
messages: Nucleus

31033:abcg4
gene id: 31033:abcg4
uniprot id: A0A674NH49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204) subfamily.
messages: Membrane

31033:eef1b2
gene id: 31033:eef1b2
uniprot id: H2TXT3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the EF-1-beta/EF-1-delta family.
messages: EF-1 is composed of 4 subunits: alpha, beta, delta, and gamma.
messages: EF-1-beta and EF-1-delta stimulate the exchange of GDP bound to EF-1-alpha to GTP.

31033:LOC101071831
gene id: 31033:LOC101071831
uniprot id: A0A3B5KGV7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

31033:amhr2
gene id: 31033:amhr2
uniprot id: I0IUI9
names: Similarity
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.

31033:wnt10b
gene id: 31033:wnt10b
uniprot id: H2TUW6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

31033:LOC101072247
gene id: 31033:LOC101072247
uniprot id: A0A3B5JY66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PPP1R35 family.
messages: centriole

31033:LOC101074049
gene id: 31033:LOC101074049
uniprot id: A0A3B5K0C2
uniprot id: H2RSW0
names: Subcellular Location Annotation
messages: Membrane

31033:LOC101077835
gene id: 31033:LOC101077835
uniprot id: A0A674MR02
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

31033:LOC101065256
gene id: 31033:LOC101065256
uniprot id: H2RSI5
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Binds to various kinds of negatively charged substances such as heparin, phospholipids, and dextran sulfate. May prevent activation of the intrinsic blood coagulation cascade by binding to phospholipids on the surface of damaged cells.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

31033:f8
gene id: 31033:f8
uniprot id: Q804W6
names: Similarity
messages: Belongs to the multicopper oxidase family.

31033:gpatch11
gene id: 31033:gpatch11
uniprot id: A0A3B5JVA1
names: Similarity
messages: Belongs to the GPATCH11 family.

31033:LOC101068485
gene id: 31033:LOC101068485
uniprot id: H2SX79
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Putative Notch ligand involved in the mediation of Notch signaling.

31033:apoe1
gene id: 31033:apoe1
uniprot id: Q5KST9
names: Similarity
messages: Belongs to the apolipoprotein A1/A4/E family.

31033:gata4
gene id: 31033:gata4
uniprot id: H2U141
names: Subcellular Location Annotation
messages: Nucleus

31033:ctnna1
gene id: 31033:ctnna1
uniprot id: H2TXI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vinculin/alpha-catenin family.
messages: Cell membrane
messages: Membrane
messages: adherens junction
messages: cytoskeleton

31033:mag
gene id: 31033:mag
uniprot id: Q5W431
uniprot id: Q5W435
uniprot id: Q5W436
names: Subcellular Location Annotation
messages: Membrane

31033:snx17
gene id: 31033:snx17
uniprot id: H2SZU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Cytoplasmic vesicle membrane
messages: Early endosome
messages: Endosome
messages: Membrane

31033:LOC101067125
gene id: 31033:LOC101067125
uniprot id: H2TFV3
names: Similarity
messages: Belongs to the protein kinase superfamily.

31033:foxd3
gene id: 31033:foxd3
uniprot id: A0A3B5K6M1
names: Subcellular Location Annotation
messages: Nucleus

31033:LOC101078409
gene id: 31033:LOC101078409
uniprot id: H2TCD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SAM50/omp85 family.
messages: Mitochondrion outer membrane

31033:LOC101074042
gene id: 31033:LOC101074042
uniprot id: H2UA06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR0 subfamily.
messages: Cytoplasm
messages: Nucleus

31033:mcee
gene id: 31033:mcee
uniprot id: A0A674NQA2
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

31033:LOC101064972
gene id: 31033:LOC101064972
uniprot id: Q8JG07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

31033:LOC101063149
gene id: 31033:LOC101063149
uniprot id: A0A3B5KKX7
names: Similarity
messages: Belongs to the PDE6D/unc-119 family.

31033:supt5h
gene id: 31033:supt5h
uniprot id: H2RZ98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPT5 family.
messages: Nucleus

31033:qars
gene id: 31033:qars
uniprot id: A0A674PH57
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

31033:LOC101070289
gene id: 31033:LOC101070289
uniprot id: A0A173MSG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the somatotropin/prolactin family.
messages: Secreted

31033:gnb2
gene id: 31033:gnb2
uniprot id: A0A674NSM9
names: Similarity
messages: Belongs to the WD repeat G protein beta family.

31033:LOC101063605
gene id: 31033:LOC101063605
uniprot id: A0A674NCK1
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

31033:map2k1
gene id: 31033:map2k1
uniprot id: A0A674P793
names: Similarity
messages: Belongs to the protein kinase superfamily.

31033:LOC101068558
gene id: 31033:LOC101068558
uniprot id: A0A3B5K4R9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

31033:LOC101076248
gene id: 31033:LOC101076248
uniprot id: H2UDS7
names: Similarity
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.

31033:LOC115246437
gene id: 31033:LOC115246437
uniprot id: H2RQY7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase subunit 6c family.
messages: Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of 14 subunits. The complex is composed of a catalytic core of 3 subunits MT-CO1, MT-CO2 and MT-CO3, encoded in the mitochondrial DNA, and 11 supernumerary subunits COX4I, COX5A, COX5B, COX6A, COX6B, COX6C, COX7A, COX7B, COX7C, COX8 and NDUFA4, which are encoded in the nuclear genome. The complex exists as a monomer or a dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with NADH-ubiquinone oxidoreductase (complex I, CI) and ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII), resulting in different assemblies (supercomplex SCI(1)III(2)IV(1) and megacomplex MCI(2)III(2)IV(2)).
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
messages: Membrane
messages: Mitochondrion inner membrane

31033:LOC101067124
gene id: 31033:LOC101067124
uniprot id: A0A674N366
names: Similarity
messages: Belongs to the DENND11 family.

31033:ccn6
gene id: 31033:ccn6
uniprot id: A0A674P9Q1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCN family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

31033:LOC101074285
gene id: 31033:LOC101074285
uniprot id: A0A3B5K6I1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

31033:vps11
gene id: 31033:vps11
uniprot id: H2S5N0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS11 family.
messages: Cytoplasmic vesicle
messages: Early endosome
messages: Late endosome membrane
messages: Lysosome membrane
messages: Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes.
messages: autophagosome
messages: clathrin-coated vesicle

31033:LOC101062512
gene id: 31033:LOC101062512
uniprot id: H2T2A6
names: Similarity
messages: Belongs to the PI3K p85 subunit family.

31033:agrp2
gene id: 31033:agrp2
uniprot id: A0ZSG7
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

31033:slc35e1
gene id: 31033:slc35e1
uniprot id: H2SWN1
names: Subcellular Location Annotation
messages: Membrane

31033:tspan3
gene id: 31033:tspan3
uniprot id: H2T5L8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

31033:ppm1g
gene id: 31033:ppm1g
uniprot id: H2SU25
names: Similarity
messages: Belongs to the PP2C family.

31033:sin3b
gene id: 31033:sin3b
uniprot id: A0A674PDW3
names: Subcellular Location Annotation
messages: Nucleus

31033:arl2
gene id: 31033:arl2
uniprot id: H2SKW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: centrosome

31033:slc25a4
gene id: 31033:slc25a4
uniprot id: Q5KSP3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Catalyzes the exchange of ADP and ATP across the membrane.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Monomer.

http://togogenome.org/gene/31033:cd3g/d
gene id: 31033:cd3g/d
uniprot id: Q589Z0
names: Subcellular Location Annotation
messages: Membrane

31033:p2rx2
gene id: 31033:p2rx2
uniprot id: H2UU74
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the P2X receptor family.
messages: Functional P2XRs are organized as homomeric and heteromeric trimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Receptor for ATP that acts as a ligand-gated ion channel.

31033:trub2
gene id: 31033:trub2
uniprot id: H2URS1
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family.

31033:LOC101078918
gene id: 31033:LOC101078918
uniprot id: H2TTV8
names: Function
names: Similarity
messages: Belongs to the phospholipid scramblase family.
messages: May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane.

31033:ccnb1
gene id: 31033:ccnb1
uniprot id: H2TUR4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cyclin family. Cyclin AB subfamily.
messages: Essential for the control of the cell cycle at the G2/M (mitosis) transition.
messages: Interacts with the CDK1 protein kinase to form a serine/threonine kinase holoenzyme complex also known as maturation promoting factor (MPF). The cyclin subunit imparts substrate specificity to the complex.

31033:LOC101072649
gene id: 31033:LOC101072649
uniprot id: H2UNV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Elbow/Noc family.
messages: Nucleus

31033:dusp26
gene id: 31033:dusp26
uniprot id: A0A674N6V5
names: Function
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
messages: Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues within the same substrate, with a preference for phosphotyrosine as a substrate (By similarity). Involved in the modulation of AMPK and MAPK1/2 signaling pathways.
messages: Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate.

31033:fmc1
gene id: 31033:fmc1
uniprot id: A0A3B5K0I9
names: Similarity
messages: Belongs to the FMC1 family.

31033:LOC101064053
gene id: 31033:LOC101064053
uniprot id: H2SNE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

31033:LOC101065871
gene id: 31033:LOC101065871
uniprot id: Q802A2
names: Similarity
messages: Belongs to the globin family.

31033:LOC101073385
gene id: 31033:LOC101073385
uniprot id: H2S6E1
names: Subcellular Location Annotation
messages: dendrite

31033:hvcn1
gene id: 31033:hvcn1
uniprot id: H2S3D2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the hydrogen channel family.
messages: Homodimer.
messages: Membrane

31033:dbx1
gene id: 31033:dbx1
uniprot id: H2UUI5
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

31033:LOC105419466
gene id: 31033:LOC105419466
uniprot id: H2V7P7
names: Similarity
messages: Belongs to the cystatin family.

31033:ints8
gene id: 31033:ints8
uniprot id: H2T146
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Integrator subunit 8 family.
messages: Nucleus

31033:smo
gene id: 31033:smo
uniprot id: A0A674PB40
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor Fz/Smo family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

31033:LOC101079043
gene id: 31033:LOC101079043
uniprot id: H2TPQ8
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

31033:tgfb3
gene id: 31033:tgfb3
uniprot id: A0A3B5KFF1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TGF-beta family.
messages: Homodimer; disulfide-linked.
messages: Transforming growth factor beta-3 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-3 (TGF-beta-3) chains, which constitute the regulatory and active subunit of TGF-beta-3, respectively.
messages: extracellular matrix

31033:pigp
gene id: 31033:pigp
uniprot id: H2U9N8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGP family.
messages: Membrane
messages: Part of the complex catalyzing the transfer of N-acetylglucosamine from UDP-N-acetylglucosamine to phosphatidylinositol, the first step of GPI biosynthesis.

31033:suclg2
gene id: 31033:suclg2
uniprot id: H2SRU0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family. GTP-specific subunit beta subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: GTP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
messages: Heterodimer of an alpha and a beta subunit. The beta subunit determines specificity for GTP.
messages: Mitochondrion

31033:eps8l2
gene id: 31033:eps8l2
uniprot id: H2SLP7
names: Similarity
messages: Belongs to the EPS8 family.

31033:pfcyp19b-tstr
gene id: 31033:pfcyp19b-tstr
uniprot id: D2KTU7
names: Similarity
messages: Belongs to the cytochrome P450 family.

31033:LOC101076453
gene id: 31033:LOC101076453
uniprot id: H2SGY8
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

31033:nsg1
gene id: 31033:nsg1
uniprot id: H2UVG2
names: Similarity
messages: Belongs to the NSG family.

31033:adcyap1
gene id: 31033:adcyap1
uniprot id: A8DPE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glucagon family.
messages: Secreted

31033:LOC101070126
gene id: 31033:LOC101070126
uniprot id: H2UJ28
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

31033:LOC101069822
gene id: 31033:LOC101069822
uniprot id: A0A3B5K2T3
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cAMP subfamily.

31033:LOC101079729
gene id: 31033:LOC101079729
uniprot id: A0A674N3D9
names: Similarity
messages: Belongs to the globin family.

31033:mpg
gene id: 31033:mpg
uniprot id: H2TVW0
names: Function
names: Similarity
messages: Belongs to the DNA glycosylase MPG family.
messages: Hydrolysis of the deoxyribose N-glycosidic bond to excise 3-methyladenine, and 7-methylguanine from the damaged DNA polymer formed by alkylation lesions.

31033:LOC101070231
gene id: 31033:LOC101070231
uniprot id: H2UQM6
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

31033:LOC101074771
gene id: 31033:LOC101074771
uniprot id: H2T6D5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM163 family.
messages: Early endosome membrane
messages: Endosome membrane
messages: May bind zinc and other divalent cations and recruit them to vesicular organelles.
messages: Membrane
messages: synaptic vesicle membrane

31033:cmas
gene id: 31033:cmas
uniprot id: Q53IM5
names: Similarity
messages: Belongs to the CMP-NeuNAc synthase family.

31033:LOC101073398
gene id: 31033:LOC101073398
uniprot id: A0A3B5KF84
names: Similarity
messages: Belongs to the MDFI family.

31033:lsm5
gene id: 31033:lsm5
uniprot id: H2V8F9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the snRNP Sm proteins family.
messages: LSm subunits form a heteromer with a doughnut shape.
messages: Nucleus
messages: Plays a role in U6 snRNP assembly and function. Binds to the 3' end of U6 snRNA.

31033:rspo2
gene id: 31033:rspo2
uniprot id: A0A3B5KC46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the R-spondin family.
messages: Secreted

31033:LOC101069651
gene id: 31033:LOC101069651
uniprot id: H2TQH3
names: Function
names: Similarity
names: Subunit
messages: Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the succinate/malate CoA ligase alpha subunit family.
messages: In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family.

31033:rnf152
gene id: 31033:rnf152
uniprot id: H2V8I8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNF152 family.
messages: Lysosome membrane
messages: Membrane

31033:dlx5
gene id: 31033:dlx5
uniprot id: A0A3B5KF60
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the distal-less homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

31033:LOC101070267
gene id: 31033:LOC101070267
uniprot id: A0A674P3B9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

31033:gjc2
gene id: 31033:gjc2
uniprot id: A0A3B5K5E7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

31033:LOC101068762
gene id: 31033:LOC101068762
uniprot id: A0A674MNW3
names: Similarity
messages: Belongs to the phosphatase 2A regulatory subunit B family.

31033:LOC101072048
gene id: 31033:LOC101072048
uniprot id: H2SYS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

31033:LOC101078894
gene id: 31033:LOC101078894
uniprot id: A0A674MBZ2
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

31033:hs6st3
gene id: 31033:hs6st3
uniprot id: H2RY20
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate.
messages: Belongs to the sulfotransferase 6 family.
messages: Membrane

31033:eml2
gene id: 31033:eml2
uniprot id: H2UWR8
names: Similarity
messages: Belongs to the WD repeat EMAP family.

31033:LOC101071653
gene id: 31033:LOC101071653
uniprot id: A0A3B5KE07
names: Function
names: Similarity
messages: Belongs to the parvalbumin family.
messages: In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions.

31033:LOC101078705
gene id: 31033:LOC101078705
uniprot id: H2TND0
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

31033:LOC101075274
gene id: 31033:LOC101075274
uniprot id: A0A674NKE1
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

31033:lrrc8a
gene id: 31033:lrrc8a
uniprot id: H2VCE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LRRC8 family.
messages: Cell membrane
messages: Membrane

31033:crebl2
gene id: 31033:crebl2
uniprot id: H2S5N3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. ATF subfamily.
messages: Nucleus

31033:cpvl
gene id: 31033:cpvl
uniprot id: H2URV5
names: Similarity
messages: Belongs to the peptidase S10 family.

31033:sema3g
gene id: 31033:sema3g
uniprot id: A0A674MDN0
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

31033:myod2
gene id: 31033:myod2
uniprot id: Q202D3
names: Subcellular Location Annotation
names: Subunit
messages: Efficient DNA binding requires dimerization with another bHLH protein.
messages: Nucleus

31033:LOC101069314
gene id: 31033:LOC101069314
uniprot id: H2V058
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

31033:cnp
gene id: 31033:cnp
uniprot id: A0A3B5JUU3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 2H phosphoesterase superfamily. CNPase family.
messages: Exists as monomers and homodimers.
messages: Melanosome
messages: Membrane

31033:pgp
gene id: 31033:pgp
uniprot id: A0A674PQW5
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

31033:myod
gene id: 31033:myod
uniprot id: Q6Q2A8
names: Function
names: Miscellaneous
names: Subcellular Location Annotation
names: Subunit
names: Tissue Specificity
messages: Efficient DNA binding requires dimerization with another bHLH protein.
messages: Expressed in fast and myotomal muscle. Very weak expression in brain, skin and gonads.
messages: May act as a transcriptional activator that promotes transcription of muscle-specific target genes and plays a role in muscle differentiation.
messages: May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay.
messages: Most abundant isoform.
messages: Nucleus

31033:npy4r
gene id: 31033:npy4r
uniprot id: A7XY84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

31033:LOC101073915
gene id: 31033:LOC101073915
uniprot id: H2UYY3
names: Subcellular Location Annotation
messages: Nucleus

31033:dio1
gene id: 31033:dio1
uniprot id: B1B569
names: Function
names: Similarity
messages: Belongs to the iodothyronine deiodinase family.
messages: Responsible for the deiodination of T4 (3,5,3',5'-tetraiodothyronine).

31033:btd
gene id: 31033:btd
uniprot id: Q8AV84
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the carbon-nitrogen hydrolase superfamily. BTD/VNN family.
messages: Catalytic release of biotin from biocytin, the product of biotin-dependent carboxylases degradation.
messages: extracellular space

31033:LOC101066951
gene id: 31033:LOC101066951
uniprot id: Q6E5T4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

31033:cnih1
gene id: 31033:cnih1
uniprot id: A0A3B5JZ95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cornichon family.
messages: Membrane

31033:psip1
gene id: 31033:psip1
uniprot id: H2TKQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HDGF family.
messages: Nucleus

31033:dcaf11
gene id: 31033:dcaf11
uniprot id: A0A3B5KLL0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the WD repeat LEC14B family.
messages: Interacts with DDB1 and CUL4A.
messages: May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex.

31033:LOC101074654
gene id: 31033:LOC101074654
uniprot id: H2UB30
names: Similarity
messages: Belongs to the glycosyl hydrolase 56 family.

31033:LOC101069818
gene id: 31033:LOC101069818
uniprot id: A0A3B5KMG3
names: Similarity
messages: Belongs to the pyridoxine kinase family.

31033:cab39l
gene id: 31033:cab39l
uniprot id: H2SHW6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mo25 family.
messages: Component of a complex that binds and activates STK11/LKB1. In the complex, required to stabilize the interaction between CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta) and STK11/LKB1.
messages: Component of a trimeric complex composed of STK11/LKB1, STRAD (STRADA or STRADB) and CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta): the complex tethers STK11/LKB1 in the cytoplasm and stimulates its catalytic activity.

31033:gng7
gene id: 31033:gng7
uniprot id: H2UW32
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

31033:LOC101064186
gene id: 31033:LOC101064186
uniprot id: H2V821
names: Subcellular Location Annotation
messages: Membrane

31033:LOC101071000
gene id: 31033:LOC101071000
uniprot id: H2T7A2
names: Similarity
messages: Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.

31033:tmeff2
gene id: 31033:tmeff2
uniprot id: H2S1Z3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

31033:pign
gene id: 31033:pign
uniprot id: H2RK50
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGG/PIGN/PIGO family. PIGN subfamily.
messages: Endoplasmic reticulum membrane
messages: Ethanolamine phosphate transferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers ethanolamine phosphate to the first alpha-1,4-linked mannose of the glycosylphosphatidylinositol precursor of GPI-anchor.
messages: Membrane

31033:cpa1
gene id: 31033:cpa1
uniprot id: Q8UW45
names: Similarity
messages: Belongs to the peptidase M14 family.

31033:LOC101065843
gene id: 31033:LOC101065843
uniprot id: A0A674NXA6
names: Subcellular Location Annotation
messages: Membrane

31033:ptpn4
gene id: 31033:ptpn4
uniprot id: A0A674PBS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class subfamily.
messages: cytoskeleton

31033:LOC101075438
gene id: 31033:LOC101075438
uniprot id: H2UCA3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: This is a receptor for bradykinin. Could be a factor in chronic pain and inflammation.

31033:LOC101067100
gene id: 31033:LOC101067100
uniprot id: A0A674MZ07
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UQCR10/QCR9 family.
messages: Component of the ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII), a multisubunit enzyme composed of 3 respiratory subunits cytochrome b, cytochrome c1 and Rieske protein, 2 core protein subunits, and additional low-molecular weight protein subunits.
messages: Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. The cytochrome b-c1 complex catalyzes electron transfer from ubiquinol to cytochrome c, linking this redox reaction to translocation of protons across the mitochondrial inner membrane, with protons being carried across the membrane as hydrogens on the quinol. In the process called Q cycle, 2 protons are consumed from the matrix, 4 protons are released into the intermembrane space and 2 electrons are passed to cytochrome c.
messages: Membrane
messages: Mitochondrion inner membrane

31033:LOC101074909
gene id: 31033:LOC101074909
uniprot id: A0A674N8W7
names: Function
names: Similarity
messages: Belongs to the rod/cone cGMP-PDE gamma subunit family.
messages: Participates in processes of transmission and amplification of the visual signal. cGMP-PDEs are the effector molecules in G-protein-mediated phototransduction in vertebrate rods and cones.

31033:LOC101079325
gene id: 31033:LOC101079325
uniprot id: H2UTT7
names: Similarity
messages: Belongs to the FBPase class 1 family.

31033:lamtor5
gene id: 31033:lamtor5
uniprot id: A0A3B5K419
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LAMTOR5 family.
messages: Lysosome

31033:LOC101074738
gene id: 31033:LOC101074738
uniprot id: H2TKJ9
names: Subcellular Location Annotation
messages: Nucleus

31033:LOC101062167
gene id: 31033:LOC101062167
uniprot id: Q1KKX5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family. Labial subfamily.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

31033:plod2
gene id: 31033:plod2
uniprot id: A5A6S3
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane

31033:LOC101075563
gene id: 31033:LOC101075563
uniprot id: H2V8F4
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the aldo/keto reductase family.
messages: Cell membrane
messages: Membrane
messages: cytosol

31033:LOC101068014
gene id: 31033:LOC101068014
uniprot id: Q1KL11
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family. Proboscipedia subfamily.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

31033:pdik1l
gene id: 31033:pdik1l
uniprot id: A0A3B5KRP8
names: Similarity
messages: Belongs to the protein kinase superfamily.

31033:hmbs
gene id: 31033:hmbs
uniprot id: A0A674PK14
uniprot id: H2TLD4
names: Similarity
messages: Belongs to the HMBS family.

31033:LOC101065606
gene id: 31033:LOC101065606
uniprot id: A0A674MJ48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MiT/TFE family.
messages: Nucleus

31033:stx10
gene id: 31033:stx10
uniprot id: A0A3B5K5W3
names: Subcellular Location Annotation
messages: Golgi apparatus membrane

31033:fut7
gene id: 31033:fut7
uniprot id: H2S0F8
uniprot id: Q70AH2
uniprot id: Q70AH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 10 family.
messages: Golgi stack membrane

31033:LOC101075877
gene id: 31033:LOC101075877
uniprot id: H2S3P1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family. KCNJ2 subfamily.
messages: Membrane

31033:cfl1
gene id: 31033:cfl1
uniprot id: H2U377
names: Similarity
messages: Belongs to the actin-binding proteins ADF family.

31033:tfap2e
gene id: 31033:tfap2e
uniprot id: H2TCX9
names: Similarity
messages: Belongs to the AP-2 family.

31033:LOC101071141
gene id: 31033:LOC101071141
uniprot id: H2UX76
names: Subcellular Location Annotation
messages: Membrane

31033:trpv2
gene id: 31033:trpv2
uniprot id: H2RNL5
names: Subcellular Location Annotation
messages: Membrane

31033:hcrtr2
gene id: 31033:hcrtr2
uniprot id: H2UQF0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

31033:LOC101076802
gene id: 31033:LOC101076802
uniprot id: A0A674NDB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STT3 family.
messages: Membrane

31033:LOC101072357
gene id: 31033:LOC101072357
uniprot id: A0A674NP71
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

31033:LOC101067138
gene id: 31033:LOC101067138
uniprot id: H2SVV3
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

31033:foxf2
gene id: 31033:foxf2
uniprot id: H2T0M4
names: Subcellular Location Annotation
messages: Nucleus

31033:fez1
gene id: 31033:fez1
uniprot id: H2SIU5
names: Similarity
messages: Belongs to the zygin family.

31033:ninj1
gene id: 31033:ninj1
uniprot id: H2UC52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ninjurin family.
messages: Membrane

31033:LOC101068078
gene id: 31033:LOC101068078
uniprot id: H2V4Y2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anoctamin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

31033:asl
gene id: 31033:asl
uniprot id: H2U7E4
names: Similarity
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.

31033:LOC101063464
gene id: 31033:LOC101063464
uniprot id: A0A674PNR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Musashi family.
messages: Cytoplasm

31033:slc39a9
gene id: 31033:slc39a9
uniprot id: A0A3B5K8G6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZIP transporter (TC 2.A.5) family.
messages: May act as a zinc-influx transporter.
messages: Membrane

31033:tmem98
gene id: 31033:tmem98
uniprot id: H2UZU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM98 family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: extracellular exosome

31033:tmem161b
gene id: 31033:tmem161b
uniprot id: A0A3B5JY53
uniprot id: A0A3B5KFM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM161 family.
messages: Membrane

31033:LOC101071451
gene id: 31033:LOC101071451
uniprot id: H2TVT8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Caudal homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

31033:baz1b
gene id: 31033:baz1b
uniprot id: H2SP38
names: Subcellular Location Annotation
messages: Nucleus

31033:mcrip1
gene id: 31033:mcrip1
uniprot id: A0A674NV26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCRIP family.
messages: Nucleus
messages: Stress granule

31033:rdh10
gene id: 31033:rdh10
uniprot id: A0A674MEX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Microsome membrane

31033:mfsd4a
gene id: 31033:mfsd4a
uniprot id: H2UAH9
names: Subcellular Location Annotation
messages: Membrane

31033:LOC101064646
gene id: 31033:LOC101064646
uniprot id: A0A3B5K642
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

31033:LOC101078868
gene id: 31033:LOC101078868
uniprot id: A0A674NME4
names: Similarity
messages: Belongs to the BRINP family.

31033:LOC105419977
gene id: 31033:LOC105419977
uniprot id: A0A3B5KD15
uniprot id: A0A674MRH6
uniprot id: Q1KKU6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Belongs to the Antp homeobox family. Deformed subfamily.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

31033:LOC101067792
gene id: 31033:LOC101067792
uniprot id: H2SFX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
messages: Membrane

31033:LOC101075190
gene id: 31033:LOC101075190
uniprot id: A0A3B5KDT6
names: Function
names: Similarity
messages: Belongs to the 5'-AMP-activated protein kinase beta subunit family.
messages: Non-catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton; probably by indirectly activating myosin. Beta non-catalytic subunit acts as a scaffold on which the AMPK complex assembles, via its C-terminus that bridges alpha (PRKAA1 or PRKAA2) and gamma subunits (PRKAG1, PRKAG2 or PRKAG3).

31033:LOC101069170
gene id: 31033:LOC101069170
uniprot id: H2RWL3
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

31033:junb
gene id: 31033:junb
uniprot id: Q800B3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. Jun subfamily.
messages: Nucleus

31033:crybb1
gene id: 31033:crybb1
uniprot id: H2VEL6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the beta/gamma-crystallin family.
messages: Crystallins are the dominant structural components of the vertebrate eye lens.
messages: Homo/heterodimer, or complexes of higher-order. The structure of beta-crystallin oligomers seems to be stabilized through interactions between the N-terminal arms.

31033:med29
gene id: 31033:med29
uniprot id: A0A3B5KIZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 29 family.
messages: Nucleus

31033:LOC101068939
gene id: 31033:LOC101068939
uniprot id: A0A6D2XGU2
names: Similarity
messages: Belongs to the eukaryotic diacylglycerol kinase family.

31033:elavl3
gene id: 31033:elavl3
uniprot id: A0A674N7T6
names: Similarity
messages: Belongs to the RRM elav family.

31033:kif11
gene id: 31033:kif11
uniprot id: H2U1Z5
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

31033:cldn15
gene id: 31033:cldn15
uniprot id: H2UQA1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

31033:LOC101076659
gene id: 31033:LOC101076659
uniprot id: A0A674PGT6
names: Similarity
messages: Belongs to the peptidase C1 family.

31033:ppp2r5a
gene id: 31033:ppp2r5a
uniprot id: A0A3B5JZS8
names: Similarity
messages: Belongs to the phosphatase 2A regulatory subunit B56 family.

31033:slc25a15
gene id: 31033:slc25a15
uniprot id: A0A3B5K1Q6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

31033:kcns2
gene id: 31033:kcns2
uniprot id: H2TT92
names: Subcellular Location Annotation
messages: Membrane

31033:vwf
gene id: 31033:vwf
uniprot id: F5XVC6
names: Subcellular Location Annotation
names: Subunit
messages: Multimeric. Interacts with F8.
messages: extracellular matrix

31033:LOC101076480
gene id: 31033:LOC101076480
uniprot id: S0BBV7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Membrane

31033:psenen
gene id: 31033:psenen
uniprot id: A0A3B5KN82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEN-2 family.
messages: Golgi stack membrane
messages: Membrane

31033:emc3
gene id: 31033:emc3
uniprot id: A0A674NM90
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EMC3 family.
messages: Component of the ER membrane protein complex (EMC).
messages: Membrane

31033:hira
gene id: 31033:hira
uniprot id: O42611
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat HIR1 family.
messages: Nucleus
messages: Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle.

31033:LOC101064904
gene id: 31033:LOC101064904
uniprot id: H2TRX2
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

31033:rps21
gene id: 31033:rps21
uniprot id: H2RKP1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS21 family.
messages: Component of the 40S small ribosomal subunit.
messages: Endoplasmic reticulum
messages: Rough endoplasmic reticulum
messages: cytosol

31033:eri1
gene id: 31033:eri1
uniprot id: A0A674PQ98
names: Subcellular Location Annotation
messages: Cytoplasm

31033:mrpl34
gene id: 31033:mrpl34
uniprot id: A0A674N9R0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

31033:nme3
gene id: 31033:nme3
uniprot id: H2SQ33
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Major role in the synthesis of nucleoside triphosphates other than ATP.
messages: Nucleus
messages: lamellipodium
messages: ruffle

31033:capg
gene id: 31033:capg
uniprot id: A0A3B5KDK7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the villin/gelsolin family.
messages: Calcium-sensitive protein which reversibly blocks the barbed ends of actin filaments but does not sever preformed actin filaments. May play an important role in macrophage function. May play a role in regulating cytoplasmic and/or nuclear structures through potential interactions with actin. May bind DNA.
messages: Cytoplasm
messages: Melanosome
messages: Nucleus
messages: lamellipodium
messages: ruffle

31033:LOC101073139
gene id: 31033:LOC101073139
uniprot id: H2TKD8
names: Function
names: Similarity
messages: Belongs to the calponin family.
messages: Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity.

31033:rhcg
gene id: 31033:rhcg
uniprot id: Q18PF5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
names: Tissue Specificity
messages: Apical cell membrane
messages: Belongs to the ammonium transporter (TC 2.A.49) family. Rh subfamily.
messages: Functions as an ammonia transporter. May play a role in the elimination of ammonia in the gill.
messages: Homotrimer.
messages: Specifically expressed in the gill by mitochondria-rich cells.

31033:mc4r
gene id: 31033:mc4r
uniprot id: Q90VY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane

31033:spon2
gene id: 31033:spon2
uniprot id: H2UPX8
names: Subcellular Location Annotation
messages: extracellular matrix

31033:LOC101067599
gene id: 31033:LOC101067599
uniprot id: A0A3B5JZS7
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

31033:LOC101079688
gene id: 31033:LOC101079688
uniprot id: A0A674MXD5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

31033:LOC101076820
gene id: 31033:LOC101076820
uniprot id: A0A3B5K9Q1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate.
messages: Belongs to the sulfotransferase 6 family.
messages: Membrane

31033:vwc2
gene id: 31033:vwc2
uniprot id: H2V8Q5
names: Subcellular Location Annotation
messages: Synapse

31033:LOC101064257
gene id: 31033:LOC101064257
uniprot id: H2U5X2
names: Function
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

31033:cd28
gene id: 31033:cd28
uniprot id: A1L4S4
uniprot id: H2T9J0
names: Subcellular Location Annotation
messages: Membrane

31033:eif4a2
gene id: 31033:eif4a2
uniprot id: A0A3B5K7V9
names: Similarity
messages: Belongs to the DEAD box helicase family. eIF4A subfamily.

31033:pax6
gene id: 31033:pax6
uniprot id: A0A674NSN2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

31033:sirt5
gene id: 31033:sirt5
uniprot id: H2U3N7
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sirtuin family. Class III subfamily.
messages: Binds 1 zinc ion per subunit.
messages: In contrast to class I sirtuins, class III sirtuins have only weak deacetylase activity. Difference in substrate specificity is probably due to a larger hydrophobic pocket with 2 residues (Tyr-95 and Arg-98) that bind to malonylated and succinylated substrates and define the specificity.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mitochondrion
messages: NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo.
messages: Nucleus
messages: cytosol

31033:LOC101071345
gene id: 31033:LOC101071345
uniprot id: Q69A05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transcription factor STAT family.
messages: Cytoplasm
messages: Nucleus

31033:vegfc
gene id: 31033:vegfc
uniprot id: H2TYL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PDGF/VEGF growth factor family.
messages: Secreted

31033:tmt-opsin
gene id: 31033:tmt-opsin
uniprot id: Q8JI05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
messages: Membrane

31033:tyw3
gene id: 31033:tyw3
uniprot id: A0A3B5KD86
names: Function
names: Similarity
messages: Belongs to the TYW3 family.
messages: Probable S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA.

31033:LOC101066150
gene id: 31033:LOC101066150
uniprot id: A0A3B5K7T3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the shaker potassium channel beta subunit family.
messages: Cell membrane
messages: Membrane
messages: axon
messages: cytoskeleton
messages: synaptosome

31033:nptx1
gene id: 31033:nptx1
uniprot id: H2SES0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

31033:LOC101072562
gene id: 31033:LOC101072562
uniprot id: A0A674MZU5
names: Function
messages: Regulates (in vitro) the inhibition of rhodopsin phosphorylation in a calcium-dependent manner.

31033:arl6ip5
gene id: 31033:arl6ip5
uniprot id: H2U2I1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA1 family.
messages: Membrane

31033:LOC101070637
gene id: 31033:LOC101070637
uniprot id: A0A674MH25
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

31033:LOC101070680
gene id: 31033:LOC101070680
uniprot id: A0A3B5KLV8
names: Similarity
messages: Belongs to the DEAD box helicase family.

31033:LOC101066121
gene id: 31033:LOC101066121
uniprot id: H2T8N8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

31033:pdx1
gene id: 31033:pdx1
uniprot id: H2SN16
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

31033:emp1
gene id: 31033:emp1
uniprot id: A0A3B5KP35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family.
messages: Membrane

31033:smc6
gene id: 31033:smc6
uniprot id: Q802R8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family. SMC6 subfamily.
messages: Chromosome
messages: Core component of the SMC5-SMC6 complex, a complex involved in repair of DNA double-strand breaks by homologous recombination. The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks. The complex is required for telomere maintenance via recombination and mediates sumoylation of shelterin complex (telosome) components (By similarity).
messages: Forms a heterodimer with smc5. Component of the SMC5-SMC6 complex which consists at least of smc5, smc6, nsmce2, nsmce1 and nsmce4a (By similarity).
messages: Nucleus
messages: The flexible hinge domain, which separates the large intramolecular coiled coil regions, allows the heterotypic interaction with the corresponding domain of SMC5, forming a V-shaped heterodimer.
messages: telomere

31033:fam20a
gene id: 31033:fam20a
uniprot id: A0A6D2Y359
uniprot id: H2V074
names: Similarity
messages: Belongs to the FAM20 family.

31033:LOC101065410
gene id: 31033:LOC101065410
uniprot id: H2UUX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HARBI1 family.
messages: Nucleus

31033:c12h18orf21
gene id: 31033:c12h18orf21
uniprot id: A0A3B5JYK4
names: Similarity
messages: Belongs to the UPF0711 family.

31033:LOC101072454
gene id: 31033:LOC101072454
uniprot id: A0A3B5K9J5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

31033:LOC101070549
gene id: 31033:LOC101070549
uniprot id: H2SE13
names: Similarity
messages: Belongs to the inositol 1,4,5-trisphosphate 5-phosphatase type I family.

31033:dnajc16
gene id: 31033:dnajc16
uniprot id: H2V883
names: Subcellular Location Annotation
messages: Membrane

31033:npy7r
gene id: 31033:npy7r
uniprot id: A7XY85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

31033:eif4ebp3
gene id: 31033:eif4ebp3
uniprot id: H2RZT6
names: Similarity
messages: Belongs to the eIF4E-binding protein family.

31033:mfsd11
gene id: 31033:mfsd11
uniprot id: H2RVG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unc-93 family.
messages: Membrane

31033:rnf2
gene id: 31033:rnf2
uniprot id: A0A3B5KTP7
names: Subcellular Location Annotation
messages: Chromosome
messages: Cytoplasm

31033:LOC101062249
gene id: 31033:LOC101062249
uniprot id: H2U3P8
names: Subcellular Location Annotation
messages: Membrane