309799:DICTH RS09585
gene id: 309799:DICTH_RS09585
uniprot id: B5YCC9
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

309799:DICTH RS02550
gene id: 309799:DICTH_RS02550
uniprot id: B5YD13
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LDH/MDH superfamily. LDH family.
messages: Catalyzes the conversion of lactate to pyruvate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

309799:DICTH RS06240
gene id: 309799:DICTH_RS06240
uniprot id: B5YF06
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MinC family.
messages: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.
messages: Interacts with MinD and FtsZ.

309799:DICTH RS05610
gene id: 309799:DICTH_RS05610
uniprot id: B5YEP3
names: Similarity
messages: Belongs to the PGI/PMI family.

309799:DICTH RS06025
gene id: 309799:DICTH_RS06025
uniprot id: B5YEX1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

309799:DICTH RS06230
gene id: 309799:DICTH_RS06230
uniprot id: B5YF04
names: Function
names: Similarity
messages: Belongs to the MinE family.
messages: Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.

309799:DICTH RS07630
gene id: 309799:DICTH_RS07630
uniprot id: B5YAC4
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

309799:DICTH RS01525
gene id: 309799:DICTH_RS01525
uniprot id: B5YCF3
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

309799:DICTH RS07885
gene id: 309799:DICTH_RS07885
uniprot id: B5YAH2
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

309799:DICTH RS03605
gene id: 309799:DICTH_RS03605
uniprot id: B5YDL1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

309799:DICTH RS08325
gene id: 309799:DICTH_RS08325
uniprot id: B5YAQ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MurCDEF family. MurT subfamily.
messages: Forms a heterodimer with GatD.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The MurT subunit catalyzes the ATP-dependent amidation of D-glutamate residue of lipid II, converting it to an isoglutamine residue.

309799:DICTH RS07205
gene id: 309799:DICTH_RS07205
uniprot id: B5YFK2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

309799:DICTH RS00795
gene id: 309799:DICTH_RS00795
uniprot id: B5YBH9
names: Similarity
messages: In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.
messages: In the central section; belongs to the CRISPR-associated helicase Cas3 family.

309799:DICTH RS01845
gene id: 309799:DICTH_RS01845
uniprot id: B5YCM1
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family.

309799:DICTH RS00070
gene id: 309799:DICTH_RS00070
uniprot id: B5YAS6
names: Subcellular Location Annotation
messages: Membrane

309799:DICTH RS03220
gene id: 309799:DICTH_RS03220
uniprot id: B5YDD9
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.

309799:DICTH RS05470
gene id: 309799:DICTH_RS05470
uniprot id: B5YEL3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell inner membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).

309799:DICTH RS05605
gene id: 309799:DICTH_RS05605
uniprot id: B5YEP2
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

309799:DICTH RS03430
gene id: 309799:DICTH_RS03430
uniprot id: B5YDH9
names: Similarity
messages: Belongs to the UPF0473 family.

309799:DICTH RS06940
gene id: 309799:DICTH_RS06940
uniprot id: B5YFE9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

309799:DICTH RS01145
gene id: 309799:DICTH_RS01145
uniprot id: B5YC15
names: Similarity
messages: Belongs to the HepT RNase toxin family.

309799:DICTH RS07245
gene id: 309799:DICTH_RS07245
uniprot id: B5YFL0
names: Function
names: Similarity
messages: Belongs to the QueH family.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).

309799:DICTH RS02465
gene id: 309799:DICTH_RS02465
uniprot id: B5YCZ5
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

309799:DICTH RS06870
gene id: 309799:DICTH_RS06870
uniprot id: B5YFD4
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

309799:DICTH RS06695
gene id: 309799:DICTH_RS06695
uniprot id: B5YF99
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

309799:DICTH RS08505
gene id: 309799:DICTH_RS08505
uniprot id: B5YB42
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

309799:DICTH RS02800
gene id: 309799:DICTH_RS02800
uniprot id: B5YD63
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate.
messages: Cytoplasm

309799:DICTH RS03375
gene id: 309799:DICTH_RS03375
uniprot id: B5YDH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

309799:DICTH RS05935
gene id: 309799:DICTH_RS05935
uniprot id: B5YEV3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the methylaspartate mutase GlmS subunit family.
messages: Catalyzes the carbon skeleton rearrangement of L-glutamate to L-threo-3-methylaspartate ((2S,3S)-3-methylaspartate).
messages: Heterotetramer composed of 2 epsilon subunits (GlmE) and 2 sigma subunits (GlmS). GlmE exists as a homodimer and GlmS as a monomer.

309799:DICTH RS05040
gene id: 309799:DICTH_RS05040
uniprot id: B5YED3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

309799:DICTH RS02525
gene id: 309799:DICTH_RS02525
uniprot id: B5YD08
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

309799:DICTH RS07610
gene id: 309799:DICTH_RS07610
uniprot id: B5YAC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

309799:DICTH RS03300
gene id: 309799:DICTH_RS03300
uniprot id: B5YDF4
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

309799:DICTH RS05140
gene id: 309799:DICTH_RS05140
uniprot id: B5YEF3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.

309799:DICTH RS01610
gene id: 309799:DICTH_RS01610
uniprot id: B5YCH2
names: Similarity
messages: Belongs to the UPF0145 family.

309799:DICTH RS06825
gene id: 309799:DICTH_RS06825
uniprot id: B5YFC5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

309799:DICTH RS06505
gene id: 309799:DICTH_RS06505
uniprot id: B5YF61
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

309799:DICTH RS08730
gene id: 309799:DICTH_RS08730
uniprot id: B5YB87
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

309799:DICTH RS08795
gene id: 309799:DICTH_RS08795
uniprot id: B5YB99
names: Subcellular Location Annotation
messages: Membrane

309799:DICTH RS08585
gene id: 309799:DICTH_RS08585
uniprot id: B5YB58
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

309799:DICTH RS05575
gene id: 309799:DICTH_RS05575
uniprot id: B5YEN6
names: Function
names: Similarity
messages: Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB. Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation. Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently.
messages: Belongs to the archease family.

309799:DICTH RS05730
gene id: 309799:DICTH_RS05730
uniprot id: B5YER2
names: Subcellular Location Annotation
messages: Membrane

309799:DICTH RS08620
gene id: 309799:DICTH_RS08620
uniprot id: B5YB65
names: Function
names: Similarity
messages: Belongs to the HypA/HybF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.

309799:DICTH RS02345
gene id: 309799:DICTH_RS02345
uniprot id: B5YCX1
names: Subcellular Location Annotation
messages: Membrane

309799:DICTH RS00180
gene id: 309799:DICTH_RS00180
uniprot id: B5YAU8
names: Similarity
messages: Belongs to the glutamate synthase family.

309799:DICTH RS02215
gene id: 309799:DICTH_RS02215
uniprot id: B5YCU5
names: Subcellular Location Annotation
messages: Membrane

309799:DICTH RS00075
gene id: 309799:DICTH_RS00075
uniprot id: B5YAS7
names: Cofactor
names: Similarity
messages: Belongs to the UPF0313 family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

309799:DICTH RS05425
gene id: 309799:DICTH_RS05425
uniprot id: B5YEK4
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

309799:DICTH RS05905
gene id: 309799:DICTH_RS05905
uniprot id: B5YEU7
names: Similarity
messages: Belongs to the class-I fumarase family.

309799:DICTH RS06830
gene id: 309799:DICTH_RS06830
uniprot id: B5YFC6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmG family. TrmFO subfamily.
messages: Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
messages: Cytoplasm

309799:DICTH RS07225
gene id: 309799:DICTH_RS07225
uniprot id: B5YFK6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

309799:DICTH RS00295
gene id: 309799:DICTH_RS00295
uniprot id: B5YAX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

309799:DICTH RS04335
gene id: 309799:DICTH_RS04335
uniprot id: B5YE05
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

309799:DICTH RS07920
gene id: 309799:DICTH_RS07920
uniprot id: B5YAH9
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

309799:DICTH RS04110
gene id: 309799:DICTH_RS04110
uniprot id: B5YDW1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

309799:DICTH RS06755
gene id: 309799:DICTH_RS06755
uniprot id: B5YFB1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

309799:DICTH RS00135
gene id: 309799:DICTH_RS00135
uniprot id: B5YAT9
names: Subcellular Location Annotation
messages: Membrane

309799:DICTH RS00595
gene id: 309799:DICTH_RS00595
uniprot id: B5YBD9
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

309799:DICTH RS05210
gene id: 309799:DICTH_RS05210
uniprot id: B5YEG8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

309799:DICTH RS02485
gene id: 309799:DICTH_RS02485
uniprot id: B5YCZ9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

309799:DICTH RS04540
gene id: 309799:DICTH_RS04540
uniprot id: B5YE42
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

309799:DICTH RS04725
gene id: 309799:DICTH_RS04725
uniprot id: B5YE71
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell inner membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

309799:DICTH RS03670
gene id: 309799:DICTH_RS03670
uniprot id: B5YDM4
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

309799:DICTH RS05205
gene id: 309799:DICTH_RS05205
uniprot id: B5YEG7
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by GTP. Inhibited by UTP.
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

309799:DICTH RS03315
gene id: 309799:DICTH_RS03315
uniprot id: B5YDF7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic riboflavin transporter (P-RFT) (TC 2.A.87) family.
messages: Cell membrane
messages: Membrane
messages: Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex.

309799:DICTH RS08255
gene id: 309799:DICTH_RS08255
uniprot id: B5YAP4
names: Function
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflC subfamily.
messages: HflC and HflK could regulate a protease.

309799:DICTH RS07000
gene id: 309799:DICTH_RS07000
uniprot id: B5YFG1
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

309799:DICTH RS01325
gene id: 309799:DICTH_RS01325
uniprot id: B5YC61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

309799:DICTH RS00905
gene id: 309799:DICTH_RS00905
uniprot id: B5YBK3
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated Csm5 family.
messages: This subunit might be involved in maturation of a crRNA intermediate to its mature form.

309799:DICTH RS00150
gene id: 309799:DICTH_RS00150
uniprot id: B5YAU1
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

309799:DICTH RS04810
gene id: 309799:DICTH_RS04810
uniprot id: B5YE88
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

309799:DICTH RS06730
gene id: 309799:DICTH_RS06730
uniprot id: B5YFA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase proteolipid subunit family.
messages: Membrane

309799:DICTH RS02440
gene id: 309799:DICTH_RS02440
uniprot id: B5YCZ0
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

309799:DICTH RS05745
gene id: 309799:DICTH_RS05745
uniprot id: B5YER5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

309799:DICTH RS01230
gene id: 309799:DICTH_RS01230
uniprot id: B5YC37
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

309799:DICTH RS06875
gene id: 309799:DICTH_RS06875
uniprot id: B5YFD5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

309799:DICTH RS09130
gene id: 309799:DICTH_RS09130
uniprot id: B5YBS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

309799:DICTH RS07145
gene id: 309799:DICTH_RS07145
uniprot id: B5YFJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

309799:DICTH RS08110
gene id: 309799:DICTH_RS08110
uniprot id: B5YAL6
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

309799:DICTH RS03835
gene id: 309799:DICTH_RS03835
uniprot id: B5YDQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell inner membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

309799:DICTH RS01985
gene id: 309799:DICTH_RS01985
uniprot id: B5YCP9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Belongs to the peroxiredoxin family. Prx6 subfamily.
messages: Cytoplasm
messages: Homodecamer. Pentamer of dimers that assemble into a ring structure.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. Although the primary sequence of this enzyme is similar to those of the 1-Cys Prx6 enzymes, its catalytic properties resemble those of the typical 2-Cys Prxs and C(R) is provided by the other dimeric subunit to form an intersubunit disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

309799:DICTH RS07060
gene id: 309799:DICTH_RS07060
uniprot id: B5YFH3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

309799:DICTH RS07075
gene id: 309799:DICTH_RS07075
uniprot id: B5YFH6
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

309799:DICTH RS05570
gene id: 309799:DICTH_RS05570
uniprot id: B5YEN5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

309799:DICTH RS01800
gene id: 309799:DICTH_RS01800
uniprot id: B5YCL2
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

309799:DICTH RS04010
gene id: 309799:DICTH_RS04010
uniprot id: B5YDU1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

309799:DICTH RS02975
gene id: 309799:DICTH_RS02975
uniprot id: B5YD91
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

309799:DICTH RS03685
gene id: 309799:DICTH_RS03685
uniprot id: B5YDM7
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

309799:DICTH RS07540
gene id: 309799:DICTH_RS07540
uniprot id: B5YAA6
names: Similarity
messages: Belongs to the serpin family.

309799:DICTH RS02910
gene id: 309799:DICTH_RS02910
uniprot id: B5YD83
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

309799:DICTH RS04580
gene id: 309799:DICTH_RS04580
uniprot id: B5YE50
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

309799:DICTH RS00325
gene id: 309799:DICTH_RS00325
uniprot id: B5YAX8
names: Similarity
messages: In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.
messages: In the central section; belongs to the CRISPR-associated helicase Cas3 family.

309799:DICTH RS03500
gene id: 309799:DICTH_RS03500
uniprot id: B5YDJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

309799:DICTH RS07545
gene id: 309799:DICTH_RS07545
uniprot id: B5YAA7
names: Similarity
messages: Belongs to the glycosyl hydrolase.

309799:DICTH RS06780
gene id: 309799:DICTH_RS06780
uniprot id: B5YFB6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

309799:DICTH RS03105
gene id: 309799:DICTH_RS03105
uniprot id: B5YDB6
names: Similarity
messages: Belongs to the LacAB/RpiB family.

309799:DICTH RS07050
gene id: 309799:DICTH_RS07050
uniprot id: B5YFH1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

309799:DICTH RS01720
gene id: 309799:DICTH_RS01720
uniprot id: B5YCJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane

309799:DICTH RS04000
gene id: 309799:DICTH_RS04000
uniprot id: B5YDT9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

309799:DICTH RS00850
gene id: 309799:DICTH_RS00850
uniprot id: B5YBJ0
names: Similarity
messages: Belongs to the glutamine synthetase family.

309799:DICTH RS04185
gene id: 309799:DICTH_RS04185
uniprot id: B5YDX6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

309799:DICTH RS03750
gene id: 309799:DICTH_RS03750
uniprot id: B5YDP0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

309799:DICTH RS06760
gene id: 309799:DICTH_RS06760
uniprot id: B5YFB2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

309799:DICTH RS04215
gene id: 309799:DICTH_RS04215
uniprot id: B5YDY2
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

309799:DICTH RS07255
gene id: 309799:DICTH_RS07255
uniprot id: B5YFL2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

309799:DICTH RS02915
gene id: 309799:DICTH_RS02915
uniprot id: B5YD84
names: Similarity
messages: Belongs to the peptidase U62 family.

309799:DICTH RS09265
gene id: 309799:DICTH_RS09265
uniprot id: B5YBV6
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

309799:DICTH RS03990
gene id: 309799:DICTH_RS03990
uniprot id: B5YDT7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

309799:DICTH RS05020
gene id: 309799:DICTH_RS05020
uniprot id: B5YEC9
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

309799:DICTH RS01850
gene id: 309799:DICTH_RS01850
uniprot id: B5YCM2
names: Similarity
messages: Belongs to the alkaline phosphatase family.

309799:DICTH RS06225
gene id: 309799:DICTH_RS06225
uniprot id: B5YF03
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

309799:DICTH RS02645
gene id: 309799:DICTH_RS02645
uniprot id: B5YD31
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
messages: Cytoplasm
messages: Homodimer. Forms a heterotetramer with IscU, interacts with other sulfur acceptors.
messages: Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.

309799:DICTH RS03455
gene id: 309799:DICTH_RS03455
uniprot id: B5YDI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell membrane
messages: Membrane

309799:DICTH RS09295
gene id: 309799:DICTH_RS09295
uniprot id: B5YBW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

309799:DICTH RS07900
gene id: 309799:DICTH_RS07900
uniprot id: B5YAH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

309799:DICTH RS08810
gene id: 309799:DICTH_RS08810
uniprot id: B5YBA5
names: Similarity
messages: Belongs to the HepT RNase toxin family.

309799:DICTH RS06885
gene id: 309799:DICTH_RS06885
uniprot id: B5YFD7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpB which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpB.

309799:DICTH RS08920
gene id: 309799:DICTH_RS08920
uniprot id: B5YBN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OXA1/ALB3/YidC family.
messages: Membrane

309799:DICTH RS05720
gene id: 309799:DICTH_RS05720
uniprot id: B5YER0
names: Similarity
messages: Belongs to the peptidase S1C family.

309799:DICTH RS02295
gene id: 309799:DICTH_RS02295
uniprot id: B5YCW1
names: Subcellular Location Annotation
messages: Membrane

309799:DICTH RS04150
gene id: 309799:DICTH_RS04150
uniprot id: B5YDW9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

309799:DICTH RS06260
gene id: 309799:DICTH_RS06260
uniprot id: B5YF10
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

309799:DICTH RS08520
gene id: 309799:DICTH_RS08520
uniprot id: B5YB45
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

309799:DICTH RS08315
gene id: 309799:DICTH_RS08315
uniprot id: B5YAQ7
names: Function
names: Similarity
messages: Belongs to the bacterioferritin family.
messages: Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.

309799:DICTH RS01250
gene id: 309799:DICTH_RS01250
uniprot id: B5YC41
names: Similarity
messages: Belongs to the peptidase C40 family.

309799:DICTH RS08665
gene id: 309799:DICTH_RS08665
uniprot id: B5YB74
names: Similarity
messages: Belongs to the HupF/HypC family.

309799:DICTH RS07015
gene id: 309799:DICTH_RS07015
uniprot id: B5YFG4
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

309799:DICTH RS01440
gene id: 309799:DICTH_RS01440
uniprot id: B5YC85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

309799:DICTH RS03180
gene id: 309799:DICTH_RS03180
uniprot id: B5YDD1
names: Function
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

309799:DICTH RS00665
gene id: 309799:DICTH_RS00665
uniprot id: B5YBF3
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

309799:DICTH RS02510
gene id: 309799:DICTH_RS02510
uniprot id: B5YD05
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.

309799:DICTH RS03945
gene id: 309799:DICTH_RS03945
uniprot id: B5YDS8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

309799:DICTH RS03955
gene id: 309799:DICTH_RS03955
uniprot id: B5YDT0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.

309799:DICTH RS03485
gene id: 309799:DICTH_RS03485
uniprot id: B5YDJ0
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.

309799:DICTH RS06920
gene id: 309799:DICTH_RS06920
uniprot id: B5YFE4
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

309799:DICTH RS04220
gene id: 309799:DICTH_RS04220
uniprot id: B5YDY3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

309799:DICTH RS00225
gene id: 309799:DICTH_RS00225
uniprot id: B5YAV7
names: Function
messages: Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins.

309799:DICTH RS04840
gene id: 309799:DICTH_RS04840
uniprot id: B5YE94
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gluconeogenesis factor family.
messages: Cytoplasm
messages: Required for morphogenesis under gluconeogenic growth conditions.

309799:DICTH RS07960
gene id: 309799:DICTH_RS07960
uniprot id: B5YAI7
names: Similarity
messages: Belongs to the iron-containing alcohol dehydrogenase family.

309799:DICTH RS01320
gene id: 309799:DICTH_RS01320
uniprot id: B5YC60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

309799:DICTH RS08235
gene id: 309799:DICTH_RS08235
uniprot id: B5YAP0
names: Function
names: Similarity
names: Subunit
messages: Associates with stalled 50S ribosomal subunits.
messages: Belongs to the NEMF family.
messages: Part of the ribosome quality control system (RQC). Recruits Ala-charged tRNA and directs the elongation of stalled nascent chains on 50S ribosomal subunits, leading to non-templated C-terminal Ala extensions (Ala tail). The Ala tail promotes nascent chain degradation. May add between 1 and at least 8 Ala residues. Binds to stalled 50S ribosomal subunits.

309799:DICTH RS06455
gene id: 309799:DICTH_RS06455
uniprot id: B5YF49
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

309799:DICTH RS02520
gene id: 309799:DICTH_RS02520
uniprot id: B5YD07
names: Similarity
messages: Belongs to the TrpF family.

309799:DICTH RS08670
gene id: 309799:DICTH_RS08670
uniprot id: B5YB75
names: Similarity
messages: Belongs to the HypD family.

309799:DICTH RS05815
gene id: 309799:DICTH_RS05815
uniprot id: B5YES9
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

309799:DICTH RS03110
gene id: 309799:DICTH_RS03110
uniprot id: B5YDB7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.

309799:DICTH RS08685
gene id: 309799:DICTH_RS08685
uniprot id: B5YB78
names: Similarity
messages: Belongs to the glycosyl hydrolase 39 family.

309799:DICTH RS09540
gene id: 309799:DICTH_RS09540
uniprot id: B5YCC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

309799:DICTH RS06845
gene id: 309799:DICTH_RS06845
uniprot id: B5YFC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

309799:DICTH RS05925
gene id: 309799:DICTH_RS05925
uniprot id: B5YEV1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the methylaspartate mutase GlmE subunit family.
messages: Catalyzes the carbon skeleton rearrangement of L-glutamate to L-threo-3-methylaspartate ((2S,3S)-3-methylaspartate).
messages: Heterotetramer composed of 2 epsilon subunits (GlmE) and 2 sigma subunits (GlmS). GlmE exists as a homodimer and GlmS as a monomer.

309799:DICTH RS03175
gene id: 309799:DICTH_RS03175
uniprot id: B5YDD0
names: Function
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

309799:DICTH RS04990
gene id: 309799:DICTH_RS04990
uniprot id: B5YEC4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell inner membrane
messages: Probably interacts with PlsX.

309799:DICTH RS01865
gene id: 309799:DICTH_RS01865
uniprot id: B5YCM5
names: Similarity
messages: Belongs to the HepT RNase toxin family.

309799:DICTH RS00310
gene id: 309799:DICTH_RS00310
uniprot id: B5YAX5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

309799:DICTH RS02480
gene id: 309799:DICTH_RS02480
uniprot id: B5YCZ8
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

309799:DICTH RS05850
gene id: 309799:DICTH_RS05850
uniprot id: B5YET6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

309799:DICTH RS04145
gene id: 309799:DICTH_RS04145
uniprot id: B5YDW8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

309799:DICTH RS08240
gene id: 309799:DICTH_RS08240
uniprot id: B5YAP1
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

309799:DICTH RS05820
gene id: 309799:DICTH_RS05820
uniprot id: B5YET0
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

309799:DICTH RS07275
gene id: 309799:DICTH_RS07275
uniprot id: B5YA54
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

309799:DICTH RS06420
gene id: 309799:DICTH_RS06420
uniprot id: B5YF42
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

309799:DICTH RS07685
gene id: 309799:DICTH_RS07685
uniprot id: B5YAD3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

309799:DICTH RS04940
gene id: 309799:DICTH_RS04940
uniprot id: B5YEB4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

309799:DICTH RS04135
gene id: 309799:DICTH_RS04135
uniprot id: B5YDW6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

309799:DICTH RS06790
gene id: 309799:DICTH_RS06790
uniprot id: B5YFB8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. N-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

309799:DICTH RS02450
gene id: 309799:DICTH_RS02450
uniprot id: B5YCZ2
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

309799:DICTH RS06035
gene id: 309799:DICTH_RS06035
uniprot id: B5YEX3
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

309799:DICTH RS09035
gene id: 309799:DICTH_RS09035
uniprot id: B5YBQ9
names: Similarity
messages: Belongs to the histone deacetylase family.

309799:DICTH RS09225
gene id: 309799:DICTH_RS09225
uniprot id: B5YBU8
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

309799:DICTH RS06855
gene id: 309799:DICTH_RS06855
uniprot id: B5YFD1
names: Similarity
messages: Belongs to the UPF0102 family.

309799:DICTH RS06135
gene id: 309799:DICTH_RS06135
uniprot id: B5YEY8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.

309799:DICTH RS04750
gene id: 309799:DICTH_RS04750
uniprot id: B5YE76
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

309799:DICTH RS09020
gene id: 309799:DICTH_RS09020
uniprot id: B5YBQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Could methylate the ribose at the nucleotide 34 wobble position in tRNA.
messages: Cytoplasm

309799:DICTH RS06605
gene id: 309799:DICTH_RS06605
uniprot id: B5YF81
names: Similarity
messages: Belongs to the ClpA/ClpB family.

309799:DICTH RS07400
gene id: 309799:DICTH_RS07400
uniprot id: B5YA78
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.
messages: Cytoplasm

309799:DICTH RS03245
gene id: 309799:DICTH_RS03245
uniprot id: B5YDE3
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

309799:DICTH RS01935
gene id: 309799:DICTH_RS01935
uniprot id: B5YCN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

309799:DICTH RS05995
gene id: 309799:DICTH_RS05995
uniprot id: B5YEW5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

309799:DICTH RS04115
gene id: 309799:DICTH_RS04115
uniprot id: B5YDW2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell inner membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

309799:DICTH RS00845
gene id: 309799:DICTH_RS00845
uniprot id: B5YBI9
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

309799:DICTH RS02890
gene id: 309799:DICTH_RS02890
uniprot id: B5YD79
names: Similarity
messages: Belongs to the glycosyl hydrolase 57 family.

309799:DICTH RS05495
gene id: 309799:DICTH_RS05495
uniprot id: B5YEL8
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

309799:DICTH RS06325
gene id: 309799:DICTH_RS06325
uniprot id: B5YF23
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

309799:DICTH RS08650
gene id: 309799:DICTH_RS08650
uniprot id: B5YB71
names: Similarity
messages: Belongs to the carbamoyltransferase HypF family.

309799:DICTH RS00320
gene id: 309799:DICTH_RS00320
uniprot id: B5YAX7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated exonuclease Cas4 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).
messages: Mg(2+) or Mn(2+) required for ssDNA cleavage activity.

309799:DICTH RS00745
gene id: 309799:DICTH_RS00745
uniprot id: B5YBG8
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

309799:DICTH RS08570
gene id: 309799:DICTH_RS08570
uniprot id: B5YB55
names: Similarity
messages: Belongs to the phosphohexose mutase family.

309799:DICTH RS00050
gene id: 309799:DICTH_RS00050
uniprot id: B5YAS2
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

309799:DICTH RS03020
gene id: 309799:DICTH_RS03020
uniprot id: B5YDA0
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

309799:DICTH RS04190
gene id: 309799:DICTH_RS04190
uniprot id: B5YDX7
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

309799:DICTH RS06265
gene id: 309799:DICTH_RS06265
uniprot id: B5YF11
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

309799:DICTH RS05960
gene id: 309799:DICTH_RS05960
uniprot id: B5YEV8
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

309799:DICTH RS04640
gene id: 309799:DICTH_RS04640
uniprot id: B5YE54
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

309799:DICTH RS03150
gene id: 309799:DICTH_RS03150
uniprot id: B5YDC5
names: Similarity
messages: Belongs to the Skp family.

309799:DICTH RS04480
gene id: 309799:DICTH_RS04480
uniprot id: B5YE31
names: Cofactor
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.

309799:DICTH RS09410
gene id: 309799:DICTH_RS09410
uniprot id: B5YC93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

309799:DICTH RS07930
gene id: 309799:DICTH_RS07930
uniprot id: B5YAI1
names: Similarity
messages: Belongs to the ribulokinase family.

309799:DICTH RS06585
gene id: 309799:DICTH_RS06585
uniprot id: B5YF77
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

309799:DICTH RS08950
gene id: 309799:DICTH_RS08950
uniprot id: B5YBP2
names: Similarity
messages: Belongs to the UPF0047 family.

309799:DICTH RS07580
gene id: 309799:DICTH_RS07580
uniprot id: B5YAB4
names: Cofactor
names: Similarity
messages: Belongs to the glycosyl hydrolase 4 family.
messages: Binds 1 NAD(+) per subunit.

309799:DICTH RS07965
gene id: 309799:DICTH_RS07965
uniprot id: B5YAI8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

309799:DICTH RS05990
gene id: 309799:DICTH_RS05990
uniprot id: B5YEW4
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

309799:DICTH RS07435
gene id: 309799:DICTH_RS07435
uniprot id: B5YA85
names: Subcellular Location Annotation
messages: Membrane

309799:DICTH RS06040
gene id: 309799:DICTH_RS06040
uniprot id: B5YEX4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

309799:DICTH RS03925
gene id: 309799:DICTH_RS03925
uniprot id: B5YDS4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

309799:DICTH RS03960
gene id: 309799:DICTH_RS03960
uniprot id: B5YDT1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

309799:DICTH RS03165
gene id: 309799:DICTH_RS03165
uniprot id: B5YDC8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

309799:DICTH RS06435
gene id: 309799:DICTH_RS06435
uniprot id: B5YF45
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

309799:DICTH RS03710
gene id: 309799:DICTH_RS03710
uniprot id: B5YDN2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

309799:DICTH RS08640
gene id: 309799:DICTH_RS08640
uniprot id: B5YB69
names: Similarity
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.

309799:DICTH RS02760
gene id: 309799:DICTH_RS02760
uniprot id: B5YD55
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

309799:DICTH RS08335
gene id: 309799:DICTH_RS08335
uniprot id: B5YAR1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

309799:DICTH RS08555
gene id: 309799:DICTH_RS08555
uniprot id: B5YB52
names: Similarity
messages: Belongs to the CinA family.

309799:DICTH RS05155
gene id: 309799:DICTH_RS05155
uniprot id: B5YEF6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 2 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

309799:DICTH RS05240
gene id: 309799:DICTH_RS05240
uniprot id: B5YEH4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

309799:DICTH RS05225
gene id: 309799:DICTH_RS05225
uniprot id: B5YEH1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

309799:DICTH RS09330
gene id: 309799:DICTH_RS09330
uniprot id: B5YBW9
names: Subcellular Location Annotation
messages: Membrane

309799:DICTH RS05900
gene id: 309799:DICTH_RS05900
uniprot id: B5YEU6
names: Similarity
messages: Belongs to the class-I fumarase family.

309799:DICTH RS04030
gene id: 309799:DICTH_RS04030
uniprot id: B5YDU5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

309799:DICTH RS07130
gene id: 309799:DICTH_RS07130
uniprot id: B5YFI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

309799:DICTH RS06865
gene id: 309799:DICTH_RS06865
uniprot id: B5YFD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

309799:DICTH RS00285
gene id: 309799:DICTH_RS00285
uniprot id: B5YAW9
names: Similarity
messages: Belongs to the bacterial solute-binding protein 1 family.

309799:DICTH RS02885
gene id: 309799:DICTH_RS02885
uniprot id: B5YD78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

309799:DICTH RS03115
gene id: 309799:DICTH_RS03115
uniprot id: B5YDB8
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

309799:DICTH RS03825
gene id: 309799:DICTH_RS03825
uniprot id: B5YDQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

309799:DICTH RS05840
gene id: 309799:DICTH_RS05840
uniprot id: B5YET4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

309799:DICTH RS08655
gene id: 309799:DICTH_RS08655
uniprot id: B5YB72
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

309799:DICTH RS03580
gene id: 309799:DICTH_RS03580
uniprot id: B5YDK6
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

309799:DICTH RS05940
gene id: 309799:DICTH_RS05940
uniprot id: B5YEV4
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

309799:DICTH RS06890
gene id: 309799:DICTH_RS06890
uniprot id: B5YFD8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

309799:DICTH RS06510
gene id: 309799:DICTH_RS06510
uniprot id: B5YF62
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
messages: Heterotetramer of two alpha and two beta chains arranged as a dimer of alpha/beta heterodimers.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain.

309799:DICTH RS00020
gene id: 309799:DICTH_RS00020
uniprot id: B5YAR6
names: Similarity
messages: Belongs to the SAICAR synthetase family.

309799:DICTH RS01385
gene id: 309799:DICTH_RS01385
uniprot id: B5YC74
names: Subcellular Location Annotation
messages: Membrane

309799:DICTH RS05480
gene id: 309799:DICTH_RS05480
uniprot id: B5YEL5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

309799:DICTH RS00445
gene id: 309799:DICTH_RS00445
uniprot id: B5YB00
names: Subcellular Location Annotation
messages: Cytoplasm

309799:DICTH RS08340
gene id: 309799:DICTH_RS08340
uniprot id: B5YAR2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

309799:DICTH RS06070
gene id: 309799:DICTH_RS06070
uniprot id: B5YEY0
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

309799:DICTH RS02455
gene id: 309799:DICTH_RS02455
uniprot id: B5YCZ3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

309799:DICTH RS08260
gene id: 309799:DICTH_RS08260
uniprot id: B5YAP5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. HflK subfamily.
messages: HflC and HflK could encode or regulate a protease.
messages: HflC and HflK may interact to form a multimeric complex.
messages: Membrane

309799:DICTH RS03100
gene id: 309799:DICTH_RS03100
uniprot id: B5YDB5
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

309799:DICTH RS07340
gene id: 309799:DICTH_RS07340
uniprot id: B5YA67
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

309799:DICTH RS04980
gene id: 309799:DICTH_RS04980
uniprot id: B5YEC2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

309799:DICTH RS05790
gene id: 309799:DICTH_RS05790
uniprot id: B5YES4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

309799:DICTH RS07095
gene id: 309799:DICTH_RS07095
uniprot id: B5YFI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

309799:DICTH RS08015
gene id: 309799:DICTH_RS08015
uniprot id: B5YAJ7
names: Subcellular Location Annotation
messages: Membrane

309799:DICTH RS01915
gene id: 309799:DICTH_RS01915
uniprot id: B5YCN5
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

309799:DICTH RS09305
gene id: 309799:DICTH_RS09305
uniprot id: B5YBW4
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

309799:DICTH RS08345
gene id: 309799:DICTH_RS08345
uniprot id: B5YAR3
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

309799:DICTH RS09350
gene id: 309799:DICTH_RS09350
uniprot id: B5YBX3
names: Similarity
messages: Belongs to the PstS family.

309799:DICTH RS02620
gene id: 309799:DICTH_RS02620
uniprot id: B5YD26
names: Subcellular Location Annotation
messages: Membrane

309799:DICTH RS05135
gene id: 309799:DICTH_RS05135
uniprot id: B5YEF2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

309799:DICTH RS07480
gene id: 309799:DICTH_RS07480
uniprot id: B5YA94
names: Function
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.

309799:DICTH RS03365
gene id: 309799:DICTH_RS03365
uniprot id: B5YDG7
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

309799:DICTH RS06185
gene id: 309799:DICTH_RS06185
uniprot id: B5YEZ7
names: Subcellular Location Annotation
messages: Cytoplasm

309799:DICTH RS08925
gene id: 309799:DICTH_RS08925
uniprot id: B5YBN7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell inner membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

309799:DICTH RS09200
gene id: 309799:DICTH_RS09200
uniprot id: B5YBU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

309799:DICTH RS04515
gene id: 309799:DICTH_RS04515
uniprot id: B5YE37
names: Similarity
messages: Belongs to the Fur family.

309799:DICTH RS07335
gene id: 309799:DICTH_RS07335
uniprot id: B5YA66
names: Function
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.
messages: This protein is a Fe-Mo-cofactor biosynthetic component.

309799:DICTH RS06340
gene id: 309799:DICTH_RS06340
uniprot id: B5YF26
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

309799:DICTH RS06360
gene id: 309799:DICTH_RS06360
uniprot id: B5YF30
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

309799:DICTH RS08495
gene id: 309799:DICTH_RS08495
uniprot id: B5YB40
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate.
messages: Homotrimer.

309799:DICTH RS01465
gene id: 309799:DICTH_RS01465
uniprot id: B5YCE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polysaccharide lyase 1 family.
messages: Secreted

309799:DICTH RS06180
gene id: 309799:DICTH_RS06180
uniprot id: B5YEZ6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

309799:DICTH RS07970
gene id: 309799:DICTH_RS07970
uniprot id: B5YAI9
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 independent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.

309799:DICTH RS03905
gene id: 309799:DICTH_RS03905
uniprot id: B5YDS0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

309799:DICTH RS06500
gene id: 309799:DICTH_RS06500
uniprot id: B5YF59
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

309799:DICTH RS06050
gene id: 309799:DICTH_RS06050
uniprot id: B5YEX6
names: Similarity
messages: Belongs to the aspartokinase family.

309799:DICTH RS06680
gene id: 309799:DICTH_RS06680
uniprot id: B5YF96
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

309799:DICTH RS04920
gene id: 309799:DICTH_RS04920
uniprot id: B5YEB0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

309799:DICTH RS06835
gene id: 309799:DICTH_RS06835
uniprot id: B5YFC7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

309799:DICTH RS02530
gene id: 309799:DICTH_RS02530
uniprot id: B5YD09
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

309799:DICTH RS03810
gene id: 309799:DICTH_RS03810
uniprot id: B5YDQ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

309799:DICTH RS03565
gene id: 309799:DICTH_RS03565
uniprot id: P09961
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 57 family.
messages: Cytoplasm
messages: This amylase is a highly liquefying-type: oligomers appeared at the beginning of incubation, followed by a graded decrease in the amounts of maltotriose, maltose and glucose in prolonged incubation.

309799:DICTH RS08220
gene id: 309799:DICTH_RS08220
uniprot id: B5YAN7
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

309799:DICTH RS07360
gene id: 309799:DICTH_RS07360
uniprot id: B5YA71
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

309799:DICTH RS06380
gene id: 309799:DICTH_RS06380
uniprot id: B5YF34
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-stimulated subfamily.
messages: Cell inner membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Requires K(+) for maximal activity.
messages: Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na(+) movement across the membrane.

309799:DICTH RS05795
gene id: 309799:DICTH_RS05795
uniprot id: B5YES5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

309799:DICTH RS04005
gene id: 309799:DICTH_RS04005
uniprot id: B5YDU0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

309799:DICTH RS07625
gene id: 309799:DICTH_RS07625
uniprot id: B5YAC3
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

309799:DICTH RS06980
gene id: 309799:DICTH_RS06980
uniprot id: B5YFF7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

309799:DICTH RS05755
gene id: 309799:DICTH_RS05755
uniprot id: B5YER7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

309799:DICTH RS05920
gene id: 309799:DICTH_RS05920
uniprot id: B5YEV0
names: Similarity
names: Subunit
messages: Belongs to the methylaspartate ammonia-lyase family.
messages: Homodimer.

309799:DICTH RS04235
gene id: 309799:DICTH_RS04235
uniprot id: B5YDY6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF nuclease family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

309799:DICTH RS05710
gene id: 309799:DICTH_RS05710
uniprot id: B5YEQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

309799:DICTH RS04645
gene id: 309799:DICTH_RS04645
uniprot id: B5YE55
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

309799:DICTH RS05725
gene id: 309799:DICTH_RS05725
uniprot id: B5YER1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

309799:DICTH RS09085
gene id: 309799:DICTH_RS09085
uniprot id: B5YBR9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell inner membrane
messages: Membrane

309799:DICTH RS00885
gene id: 309799:DICTH_RS00885
uniprot id: B5YBJ9
names: Similarity
messages: Belongs to the CRISPR-associated Cas10/Csm1 family.

309799:DICTH RS04625
gene id: 309799:DICTH_RS04625
uniprot id: B5YE51
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

309799:DICTH RS00580
gene id: 309799:DICTH_RS00580
uniprot id: B5YBD6
names: Cofactor
names: Similarity
messages: Belongs to the glycosyl hydrolase 4 family.
messages: Binds 1 NAD(+) per subunit.

309799:DICTH RS08790
gene id: 309799:DICTH_RS08790
uniprot id: B5YB98
names: Similarity
messages: Belongs to the HepT RNase toxin family.

309799:DICTH RS07655
gene id: 309799:DICTH_RS07655
uniprot id: B5YAC9
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

309799:DICTH RS03625
gene id: 309799:DICTH_RS03625
uniprot id: B5YDL5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane

309799:DICTH RS08170
gene id: 309799:DICTH_RS08170
uniprot id: B5YAM8
names: Similarity
messages: Belongs to the pyruvate kinase family.
messages: In the C-terminal section; belongs to the PEP-utilizing enzyme family.

309799:DICTH RS03160
gene id: 309799:DICTH_RS03160
uniprot id: B5YDC7
names: Function
names: Similarity
messages: Belongs to the LpxC family.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

309799:DICTH RS09185
gene id: 309799:DICTH_RS09185
uniprot id: B5YBT9
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

309799:DICTH RS00630
gene id: 309799:DICTH_RS00630
uniprot id: B5YBE6
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

309799:DICTH RS07250
gene id: 309799:DICTH_RS07250
uniprot id: B5YFL1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

309799:DICTH RS08025
gene id: 309799:DICTH_RS08025
uniprot id: B5YAJ9
names: Subcellular Location Annotation
messages: Membrane

309799:DICTH RS01475
gene id: 309799:DICTH_RS01475
uniprot id: B5YCE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

309799:DICTH RS09060
gene id: 309799:DICTH_RS09060
uniprot id: B5YBR4
names: Cofactor
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.

309799:DICTH RS08280
gene id: 309799:DICTH_RS08280
uniprot id: B5YAP9
names: Function
names: Similarity
messages: Belongs to the BPG-independent phosphoglycerate mutase family. A-PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

309799:DICTH RS04800
gene id: 309799:DICTH_RS04800
uniprot id: B5YE86
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

309799:DICTH RS01780
gene id: 309799:DICTH_RS01780
uniprot id: B5YCK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0394 family.
messages: Membrane

309799:DICTH RS07070
gene id: 309799:DICTH_RS07070
uniprot id: B5YFH5
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

309799:DICTH RS03380
gene id: 309799:DICTH_RS03380
uniprot id: B5YDH1
names: Function
names: Similarity
messages: Belongs to the methylglyoxal synthase family.
messages: Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.

309799:DICTH RS06725
gene id: 309799:DICTH_RS06725
uniprot id: B5YFA5
names: Function
names: Similarity
messages: Belongs to the V-ATPase E subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

309799:DICTH RS02725
gene id: 309799:DICTH_RS02725
uniprot id: B5YD48
names: Subcellular Location Annotation
messages: Membrane

309799:DICTH RS00080
gene id: 309799:DICTH_RS00080
uniprot id: B5YAS8
names: Similarity
messages: Belongs to the UPF0047 family.

309799:DICTH RS05190
gene id: 309799:DICTH_RS05190
uniprot id: B5YEG4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

309799:DICTH RS05810
gene id: 309799:DICTH_RS05810
uniprot id: B5YES8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell inner membrane
messages: Cytoplasm
messages: Monomer.

309799:DICTH RS04935
gene id: 309799:DICTH_RS04935
uniprot id: B5YEB3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

309799:DICTH RS00460
gene id: 309799:DICTH_RS00460
uniprot id: B5YB03
names: Subcellular Location Annotation
messages: Membrane

309799:DICTH RS07210
gene id: 309799:DICTH_RS07210
uniprot id: B5YFK3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

309799:DICTH RS09005
gene id: 309799:DICTH_RS09005
uniprot id: B5YBQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase A chain family.
messages: Cell inner membrane
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

309799:DICTH RS02390
gene id: 309799:DICTH_RS02390
uniprot id: B5YCY0
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

309799:DICTH RS05025
gene id: 309799:DICTH_RS05025
uniprot id: B5YED0
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

309799:DICTH RS04745
gene id: 309799:DICTH_RS04745
uniprot id: B5YE75
names: Subcellular Location Annotation
messages: Membrane

309799:DICTH RS01400
gene id: 309799:DICTH_RS01400
uniprot id: B5YC77
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

309799:DICTH RS04415
gene id: 309799:DICTH_RS04415
uniprot id: B5YE21
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

309799:DICTH RS05250
gene id: 309799:DICTH_RS05250
uniprot id: B5YEH6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

309799:DICTH RS00890
gene id: 309799:DICTH_RS00890
uniprot id: B5YBK0
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated Csm2 family.
messages: This subunit may be involved in monitoring complementarity of crRNA and target RNA.

309799:DICTH RS02155
gene id: 309799:DICTH_RS02155
uniprot id: B5YCT3
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

309799:DICTH RS03760
gene id: 309799:DICTH_RS03760
uniprot id: B5YDP2
names: Subcellular Location Annotation
messages: Membrane

309799:DICTH RS06795
gene id: 309799:DICTH_RS06795
uniprot id: B5YFB9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. C-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

309799:DICTH RS06900
gene id: 309799:DICTH_RS06900
uniprot id: B5YFE0
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

309799:DICTH RS04105
gene id: 309799:DICTH_RS04105
uniprot id: B5YDW0
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

309799:DICTH RS03415
gene id: 309799:DICTH_RS03415
uniprot id: B5YDH8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

309799:DICTH RS04180
gene id: 309799:DICTH_RS04180
uniprot id: B5YDX5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.

309799:DICTH RS07440
gene id: 309799:DICTH_RS07440
uniprot id: B5YA86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

309799:DICTH RS08700
gene id: 309799:DICTH_RS08700
uniprot id: B5YB82
names: Subcellular Location Annotation
messages: Membrane

309799:DICTH RS00240
gene id: 309799:DICTH_RS00240
uniprot id: B5YAW0
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

309799:DICTH RS06860
gene id: 309799:DICTH_RS06860
uniprot id: B5YFD2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

309799:DICTH RS05175
gene id: 309799:DICTH_RS05175
uniprot id: B5YEG0
names: Cofactor
names: Similarity
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.
messages: Binds 1 zinc ion per subunit.

309799:DICTH RS07760
gene id: 309799:DICTH_RS07760
uniprot id: B5YAE7
names: Subcellular Location Annotation
messages: Membrane

309799:DICTH RS04390
gene id: 309799:DICTH_RS04390
uniprot id: B5YE16
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).

309799:DICTH RS04655
gene id: 309799:DICTH_RS04655
uniprot id: B5YE57
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RnfG family.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

309799:DICTH RS08160
gene id: 309799:DICTH_RS08160
uniprot id: B5YAM6
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

309799:DICTH RS08990
gene id: 309799:DICTH_RS08990
uniprot id: B5YBQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

309799:DICTH RS03560
gene id: 309799:DICTH_RS03560
uniprot id: B5YDK3
names: Similarity
messages: Belongs to the glycosyl hydrolase 57 family.

309799:DICTH RS09300
gene id: 309799:DICTH_RS09300
uniprot id: B5YBW3
names: Function
names: Similarity
messages: Belongs to the UxaE family.
messages: Catalyzes the epimerization of D-tagaturonate (D-TagA) to D-fructuronate (D-FruA).

309799:DICTH RS06305
gene id: 309799:DICTH_RS06305
uniprot id: B5YF19
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

309799:DICTH RS07525
gene id: 309799:DICTH_RS07525
uniprot id: B5YAA3
names: Subcellular Location Annotation
messages: Membrane

309799:DICTH RS07190
gene id: 309799:DICTH_RS07190
uniprot id: B5YFK0
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus
messages: Repair polymerase that plays a key role in base-excision repair. Has 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity that removes the 5' sugar phosphate and also acts as a DNA polymerase that adds one nucleotide to the 3' end of the arising single-nucleotide gap. Conducts 'gap-filling' DNA synthesis in a stepwise distributive fashion rather than in a processive fashion as for other DNA polymerases.

309799:DICTH RS06075
gene id: 309799:DICTH_RS06075
uniprot id: B5YEY1
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

309799:DICTH RS03145
gene id: 309799:DICTH_RS03145
uniprot id: B5YDC4
names: Similarity
messages: Belongs to the Skp family.

309799:DICTH RS09135
gene id: 309799:DICTH_RS09135
uniprot id: B5YBS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

309799:DICTH RS01190
gene id: 309799:DICTH_RS01190
uniprot id: B5YC28
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family. N(4) subfamily.

309799:DICTH RS08995
gene id: 309799:DICTH_RS08995
uniprot id: B5YBQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell inner membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.

309799:DICTH RS06600
gene id: 309799:DICTH_RS06600
uniprot id: B5YF80
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

309799:DICTH RS07735
gene id: 309799:DICTH_RS07735
uniprot id: B5YAE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

309799:DICTH RS00335
gene id: 309799:DICTH_RS00335
uniprot id: B5YAY0
names: Function
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).

309799:DICTH RS03085
gene id: 309799:DICTH_RS03085
uniprot id: B5YDB2
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

309799:DICTH RS06060
gene id: 309799:DICTH_RS06060
uniprot id: B5YEX8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

309799:DICTH RS05740
gene id: 309799:DICTH_RS05740
uniprot id: B5YER4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

309799:DICTH RS07875
gene id: 309799:DICTH_RS07875
uniprot id: B5YAH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

309799:DICTH RS01715
gene id: 309799:DICTH_RS01715
uniprot id: B5YCJ5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

309799:DICTH RS02895
gene id: 309799:DICTH_RS02895
uniprot id: B5YD80
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endonuclease V family.
messages: Cytoplasm
messages: DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA.

309799:DICTH RS00805
gene id: 309799:DICTH_RS00805
uniprot id: B5YBI1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

309799:DICTH RS08400
gene id: 309799:DICTH_RS08400
uniprot id: B5YB21
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

309799:DICTH RS05130
gene id: 309799:DICTH_RS05130
uniprot id: B5YEF1
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

309799:DICTH RS00100
gene id: 309799:DICTH_RS00100
uniprot id: B5YAT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

309799:DICTH RS01360
gene id: 309799:DICTH_RS01360
uniprot id: B5YC69
names: Subcellular Location Annotation
messages: Membrane

309799:DICTH RS05945
gene id: 309799:DICTH_RS05945
uniprot id: B5YEV5
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

309799:DICTH RS05760
gene id: 309799:DICTH_RS05760
uniprot id: B5YER8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

309799:DICTH RS05715
gene id: 309799:DICTH_RS05715
uniprot id: B5YEQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

309799:DICTH RS05035
gene id: 309799:DICTH_RS05035
uniprot id: B5YED2
names: Similarity
messages: Belongs to the GSP E family.

309799:DICTH RS05260
gene id: 309799:DICTH_RS05260
uniprot id: B5YEH8
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

309799:DICTH RS04295
gene id: 309799:DICTH_RS04295
uniprot id: B5YDZ7
names: Similarity
messages: Belongs to the bacterial secretin family.

309799:DICTH RS08350
gene id: 309799:DICTH_RS08350
uniprot id: B5YAR4
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

309799:DICTH RS02070
gene id: 309799:DICTH_RS02070
uniprot id: B5YCR5
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

309799:DICTH RS04825
gene id: 309799:DICTH_RS04825
uniprot id: B5YE91
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the PRA-PH family.
messages: In the N-terminal section; belongs to the PRA-CH family.

309799:DICTH RS03495
gene id: 309799:DICTH_RS03495
uniprot id: B5YDJ2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

309799:DICTH RS00230
gene id: 309799:DICTH_RS00230
uniprot id: B5YAV8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell inner membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

309799:DICTH RS00680
gene id: 309799:DICTH_RS00680
uniprot id: B5YBF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

309799:DICTH RS04870
gene id: 309799:DICTH_RS04870
uniprot id: B5YEA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

309799:DICTH RS05660
gene id: 309799:DICTH_RS05660
uniprot id: B5YEQ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

309799:DICTH RS03095
gene id: 309799:DICTH_RS03095
uniprot id: B5YDB4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.

309799:DICTH RS03635
gene id: 309799:DICTH_RS03635
uniprot id: B5YDL7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

309799:DICTH RS06385
gene id: 309799:DICTH_RS06385
uniprot id: B5YF35
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

309799:DICTH RS07125
gene id: 309799:DICTH_RS07125
uniprot id: B5YFI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

309799:DICTH RS08905
gene id: 309799:DICTH_RS08905
uniprot id: B5YBN3
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell inner membrane
messages: Membrane

309799:DICTH RS00715
gene id: 309799:DICTH_RS00715
uniprot id: B5YBG2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

309799:DICTH RS04535
gene id: 309799:DICTH_RS04535
uniprot id: B5YE41
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

309799:DICTH RS07345
gene id: 309799:DICTH_RS07345
uniprot id: B5YA68
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 2 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

309799:DICTH RS03065
gene id: 309799:DICTH_RS03065
uniprot id: B5YDA8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

309799:DICTH RS08230
gene id: 309799:DICTH_RS08230
uniprot id: B5YAN9
names: Similarity
messages: Belongs to the shaker potassium channel beta subunit family.

309799:DICTH RS02275
gene id: 309799:DICTH_RS02275
uniprot id: B5YCV7
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

309799:DICTH RS03805
gene id: 309799:DICTH_RS03805
uniprot id: B5YDQ1
names: Similarity
messages: Belongs to the fabD family.

309799:DICTH RS00235
gene id: 309799:DICTH_RS00235
uniprot id: B5YAV9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell inner membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

309799:DICTH RS02930
gene id: 309799:DICTH_RS02930
uniprot id: B5YD87
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

309799:DICTH RS08975
gene id: 309799:DICTH_RS08975
uniprot id: B5YBP7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

309799:DICTH RS04350
gene id: 309799:DICTH_RS04350
uniprot id: B5YE08
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

309799:DICTH RS03975
gene id: 309799:DICTH_RS03975
uniprot id: B5YDT4
names: Subcellular Location Annotation
messages: Membrane

309799:DICTH RS04020
gene id: 309799:DICTH_RS04020
uniprot id: B5YDU3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

309799:DICTH RS02805
gene id: 309799:DICTH_RS02805
uniprot id: B5YD64
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

309799:DICTH RS00855
gene id: 309799:DICTH_RS00855
uniprot id: B5YBJ1
names: Similarity
messages: Belongs to the P(II) protein family.

309799:DICTH RS08195
gene id: 309799:DICTH_RS08195
uniprot id: B5YAN2
names: Similarity
messages: Belongs to the glycosyl hydrolase 130 family.

309799:DICTH RS05350
gene id: 309799:DICTH_RS05350
uniprot id: B5YEJ1
names: Cofactor
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

309799:DICTH RS07265
gene id: 309799:DICTH_RS07265
uniprot id: B5YFL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

309799:DICTH RS07065
gene id: 309799:DICTH_RS07065
uniprot id: B5YFH4
names: Cofactor
names: Similarity
messages: Belongs to the PyrK family.
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.

309799:DICTH RS08410
gene id: 309799:DICTH_RS08410
uniprot id: B5YB23
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

309799:DICTH RS06045
gene id: 309799:DICTH_RS06045
uniprot id: B5YEX5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

309799:DICTH RS07085
gene id: 309799:DICTH_RS07085
uniprot id: B5YFH8
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

309799:DICTH RS05385
gene id: 309799:DICTH_RS05385
uniprot id: B5YEJ6
names: Similarity
messages: Belongs to the CutA family.

309799:DICTH RS08330
gene id: 309799:DICTH_RS08330
uniprot id: B5YAR0
names: Caution
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Both the DNA unwinding and positive supercoiling activities require the cooperation of both domains. The cooperative action between the helicase-like and the topoisomerase domains is specific. The helicase-like domain probably does not directly unwind DNA but acts more likely by driving ATP-dependent conformational changes within the whole enzyme, functioning more like a protein motor. The 'latch' region of the N-terminal domain plays a regulatory role in the enzyme, repressing topoisomerase activity in the absence of ATP and therefore preventing the enzyme from acting as an ATP-independent relaxing enzyme; it also helps to coordinate nucleotide hydrolysis by the ATPase domain with the supercoiling activity of the topoisomerase domain.
messages: In the C-terminal section; belongs to the prokaryotic type I/III topoisomerase family.
messages: In the N-terminal section; belongs to the DEAD box helicase family. DDVD subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Modifies the topological state of DNA by introducing positive supercoils in an ATP-dependent process. It cleaves transiently a single DNA strand and remains covalently bound to the 5' DNA end through a tyrosine residue. May be involved in rewinding the DNA strands in the regions of the chromosome that have opened up to allow transcription or replication.
messages: Monomer.
messages: This enzyme is the only unique feature of hyperthermophilic bacteria/archaea discovered so far. It appears to be essential for adaptation to life at high temperatures.

309799:DICTH RS01370
gene id: 309799:DICTH_RS01370
uniprot id: B5YC71
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial solute-binding protein 2 family.
messages: Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Binds AI-2 and delivers it to the LsrC and LsrD permeases.
messages: Periplasm
messages: The complex is composed of two ATP-binding proteins (LsrA), two transmembrane proteins (LsrC and LsrD) and a solute-binding protein (LsrB).

309799:DICTH RS02335
gene id: 309799:DICTH_RS02335
uniprot id: B5YCW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

309799:DICTH RS06670
gene id: 309799:DICTH_RS06670
uniprot id: B5YF94
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

309799:DICTH RS05800
gene id: 309799:DICTH_RS05800
uniprot id: B5YES6
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

309799:DICTH RS07370
gene id: 309799:DICTH_RS07370
uniprot id: B5YA73
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

309799:DICTH RS09315
gene id: 309799:DICTH_RS09315
uniprot id: B5YBW6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

309799:DICTH RS02935
gene id: 309799:DICTH_RS02935
uniprot id: B5YD88
names: Function
names: Similarity
messages: Belongs to the ATP-dependent DNA ligase family.
messages: DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair.

309799:DICTH RS06570
gene id: 309799:DICTH_RS06570
uniprot id: B5YF74
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

309799:DICTH RS01655
gene id: 309799:DICTH_RS01655
uniprot id: B5YCI2
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

309799:DICTH RS05310
gene id: 309799:DICTH_RS05310
uniprot id: B5YEI8
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

309799:DICTH RS01375
gene id: 309799:DICTH_RS01375
uniprot id: B5YC72
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. AI-2 autoinducer porter (TC 3.A.1.2.8) family.
messages: Cell inner membrane
messages: Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (LsrA), two transmembrane proteins (LsrC and LsrD) and a solute-binding protein (LsrB).

309799:DICTH RS02415
gene id: 309799:DICTH_RS02415
uniprot id: B5YCY5
names: Similarity
messages: Belongs to the glycosyl hydrolase 57 family.

309799:DICTH RS04550
gene id: 309799:DICTH_RS04550
uniprot id: B5YE44
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

309799:DICTH RS04930
gene id: 309799:DICTH_RS04930
uniprot id: B5YEB2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

309799:DICTH RS08435
gene id: 309799:DICTH_RS08435
uniprot id: B5YB28
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

309799:DICTH RS04730
gene id: 309799:DICTH_RS04730
uniprot id: B5YE72
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

309799:DICTH RS06010
gene id: 309799:DICTH_RS06010
uniprot id: B5YEW8
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

309799:DICTH RS00625
gene id: 309799:DICTH_RS00625
uniprot id: B5YBE5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein L14 (rplN).

309799:DICTH RS08055
gene id: 309799:DICTH_RS08055
uniprot id: B5YAK5
names: Subcellular Location Annotation
messages: Membrane

309799:DICTH RS02565
gene id: 309799:DICTH_RS02565
uniprot id: B5YD16
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

309799:DICTH RS01485
gene id: 309799:DICTH_RS01485
uniprot id: B5YCE4
names: Cofactor
names: Similarity
messages: Belongs to the glycosyl hydrolase 4 family.
messages: Binds 1 NAD(+) per subunit.

309799:DICTH RS08120
gene id: 309799:DICTH_RS08120
uniprot id: B5YAL8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

309799:DICTH RS01200
gene id: 309799:DICTH_RS01200
uniprot id: B5YC30
names: Subcellular Location Annotation
messages: Membrane

309799:DICTH RS01305
gene id: 309799:DICTH_RS01305
uniprot id: B5YC54
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

309799:DICTH RS03070
gene id: 309799:DICTH_RS03070
uniprot id: B5YDA9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidylate synthase ThyX family.
messages: Binds 4 FAD per tetramer. Each FAD binding site is formed by three monomers.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
messages: Homotetramer.

309799:DICTH RS07990
gene id: 309799:DICTH_RS07990
uniprot id: B5YAJ2
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

309799:DICTH RS00960
gene id: 309799:DICTH_RS00960
uniprot id: B5YBL5
names: Subcellular Location Annotation
messages: Membrane

309799:DICTH RS06745
gene id: 309799:DICTH_RS06745
uniprot id: B5YFA9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

309799:DICTH RS06005
gene id: 309799:DICTH_RS06005
uniprot id: B5YEW7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

309799:DICTH RS06355
gene id: 309799:DICTH_RS06355
uniprot id: B5YF29
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

309799:DICTH RS06970
gene id: 309799:DICTH_RS06970
uniprot id: B5YFF5
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

309799:DICTH RS05000
gene id: 309799:DICTH_RS05000
uniprot id: B5YEC6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

309799:DICTH RS06550
gene id: 309799:DICTH_RS06550
uniprot id: B5YF70
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

309799:DICTH RS08105
gene id: 309799:DICTH_RS08105
uniprot id: B5YAL5
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

309799:DICTH RS09230
gene id: 309799:DICTH_RS09230
uniprot id: B5YBU9
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

309799:DICTH RS06425
gene id: 309799:DICTH_RS06425
uniprot id: B5YF43
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.

309799:DICTH RS08680
gene id: 309799:DICTH_RS08680
uniprot id: B5YB77
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

309799:DICTH RS05200
gene id: 309799:DICTH_RS05200
uniprot id: B5YEG6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

309799:DICTH RS04700
gene id: 309799:DICTH_RS04700
uniprot id: B5YE66
names: Similarity
messages: Belongs to the peptidase S41A family.

309799:DICTH RS08285
gene id: 309799:DICTH_RS08285
uniprot id: B5YAQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
messages: Cytoplasm
messages: Homodimer. Forms a heterotetramer with IscU, interacts with other sulfur acceptors.
messages: Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.

309799:DICTH RS03965
gene id: 309799:DICTH_RS03965
uniprot id: B5YDT2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

309799:DICTH RS08320
gene id: 309799:DICTH_RS08320
uniprot id: B5YAQ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CobB/CobQ family. GatD subfamily.
messages: Forms a heterodimer with MurT.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The GatD subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia. The resulting ammonia molecule is channeled to the active site of MurT.

309799:DICTH RS07640
gene id: 309799:DICTH_RS07640
uniprot id: B5YAC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protease PrsW family.
messages: Cell membrane
messages: Membrane

309799:DICTH RS04325
gene id: 309799:DICTH_RS04325
uniprot id: B5YE03
names: Similarity
messages: Belongs to the asp23 family.

309799:DICTH RS01350
gene id: 309799:DICTH_RS01350
uniprot id: B5YC67
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L-fucose isomerase family.
messages: Converts the aldose L-fucose into the corresponding ketose L-fuculose.
messages: Cytoplasm

309799:DICTH RS02815
gene id: 309799:DICTH_RS02815
uniprot id: B5YD67
names: Function
names: Similarity
messages: Belongs to the PduL family.
messages: Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate.

309799:DICTH RS00605
gene id: 309799:DICTH_RS00605
uniprot id: B5YBE1
names: Subcellular Location Annotation
messages: Membrane

309799:DICTH RS08385
gene id: 309799:DICTH_RS08385
uniprot id: B5YB18
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

309799:DICTH RS04035
gene id: 309799:DICTH_RS04035
uniprot id: B5YDU6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

309799:DICTH RS02995
gene id: 309799:DICTH_RS02995
uniprot id: B5YD95
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

309799:DICTH RS08980
gene id: 309799:DICTH_RS08980
uniprot id: B5YBP8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

309799:DICTH RS03940
gene id: 309799:DICTH_RS03940
uniprot id: B5YDS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

309799:DICTH RS06080
gene id: 309799:DICTH_RS06080
uniprot id: B5YEY2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell inner membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

309799:DICTH RS03210
gene id: 309799:DICTH_RS03210
uniprot id: B5YDD7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.
messages: Cytoplasm
messages: Homodimer.

309799:DICTH RS05215
gene id: 309799:DICTH_RS05215
uniprot id: B5YEG9
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

309799:DICTH RS04355
gene id: 309799:DICTH_RS04355
uniprot id: B5YE09
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

309799:DICTH RS08715
gene id: 309799:DICTH_RS08715
uniprot id: B5YB85
names: Function
names: Similarity
messages: A P subtype restriction enzyme that recognizes the double-stranded unmethylated sequence 5'-GATC-3'.
messages: Belongs to the DpnII type II restriction endonuclease family.

309799:DICTH RS04025
gene id: 309799:DICTH_RS04025
uniprot id: B5YDU4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

309799:DICTH RS04170
gene id: 309799:DICTH_RS04170
uniprot id: B5YDX3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex.
messages: Belongs to the ABC transporter superfamily. Energy-coupling factor EcfA family.
messages: Cell membrane
messages: Forms a stable energy-coupling factor (ECF) transporter complex composed of 2 membrane-embedded substrate-binding proteins (S component), 2 ATP-binding proteins (A component) and 2 transmembrane proteins (T component).

309799:DICTH RS01210
gene id: 309799:DICTH_RS01210
uniprot id: B5YC32
names: Similarity
messages: Belongs to the HepT RNase toxin family.

309799:DICTH RS03970
gene id: 309799:DICTH_RS03970
uniprot id: B5YDT3
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

309799:DICTH RS06515
gene id: 309799:DICTH_RS06515
uniprot id: B5YF63
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

309799:DICTH RS08675
gene id: 309799:DICTH_RS08675
uniprot id: B5YB76
names: Similarity
messages: Belongs to the HypE family.

309799:DICTH RS06290
gene id: 309799:DICTH_RS06290
uniprot id: B5YF16
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell inner membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

309799:DICTH RS04915
gene id: 309799:DICTH_RS04915
uniprot id: B5YEA9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

309799:DICTH RS04340
gene id: 309799:DICTH_RS04340
uniprot id: B5YE06
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

309799:DICTH RS02300
gene id: 309799:DICTH_RS02300
uniprot id: B5YCW2
names: Function
names: Similarity
messages: Belongs to the N-acylglucosamine 2-epimerase family.
messages: Belongs to the cellobiose 2-epimerase family.
messages: Catalyzes the reversible epimerization of cellobiose to 4-O-beta-D-glucopyranosyl-D-mannose (Glc-Man).

309799:DICTH RS08115
gene id: 309799:DICTH_RS08115
uniprot id: B5YAL7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

309799:DICTH RS04945
gene id: 309799:DICTH_RS04945
uniprot id: B5YEB5
names: Similarity
messages: Belongs to the FtsK/SpoIIIE/SftA family.

309799:DICTH RS03250
gene id: 309799:DICTH_RS03250
uniprot id: B5YDE4
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

309799:DICTH RS02190
gene id: 309799:DICTH_RS02190
uniprot id: B5YCU0
names: Similarity
messages: Belongs to the glycosyl hydrolase 26 family.

309799:DICTH RS03800
gene id: 309799:DICTH_RS03800
uniprot id: B5YDQ0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

309799:DICTH RS01890
gene id: 309799:DICTH_RS01890
uniprot id: B5YCN0
names: Similarity
messages: Belongs to the shaker potassium channel beta subunit family.

309799:DICTH RS04805
gene id: 309799:DICTH_RS04805
uniprot id: B5YE87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

309799:DICTH RS01765
gene id: 309799:DICTH_RS01765
uniprot id: B5YCK5
names: Similarity
messages: Belongs to the glycosyl hydrolase 42 family.

309799:DICTH RS02795
gene id: 309799:DICTH_RS02795
uniprot id: B5YD62
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

309799:DICTH RS04860
gene id: 309799:DICTH_RS04860
uniprot id: B5YE98
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Membrane

309799:DICTH RS08545
gene id: 309799:DICTH_RS08545
uniprot id: B5YB50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

309799:DICTH RS04305
gene id: 309799:DICTH_RS04305
uniprot id: B5YDZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

309799:DICTH RS09195
gene id: 309799:DICTH_RS09195
uniprot id: B5YBU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

309799:DICTH RS05510
gene id: 309799:DICTH_RS05510
uniprot id: B5YEM1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

309799:DICTH RS04070
gene id: 309799:DICTH_RS04070
uniprot id: B5YDV3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

309799:DICTH RS00025
gene id: 309799:DICTH_RS00025
uniprot id: B5YAR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Membrane

309799:DICTH RS01460
gene id: 309799:DICTH_RS01460
uniprot id: B5YCD9
names: Similarity
messages: Belongs to the desulfoferrodoxin family.

309799:DICTH RS03700
gene id: 309799:DICTH_RS03700
uniprot id: B5YDN0
names: Similarity
messages: Belongs to the AdoMet synthetase 2 family.

309799:DICTH RS01830
gene id: 309799:DICTH_RS01830
uniprot id: B5YCL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

309799:DICTH RS03155
gene id: 309799:DICTH_RS03155
uniprot id: B5YDC6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

309799:DICTH RS03985
gene id: 309799:DICTH_RS03985
uniprot id: B5YDT6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

309799:DICTH RS07870
gene id: 309799:DICTH_RS07870
uniprot id: B5YAG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

309799:DICTH RS02685
gene id: 309799:DICTH_RS02685
uniprot id: B5YD39
names: Similarity
messages: Belongs to the methylamine corrinoid protein family.

309799:DICTH RS01445
gene id: 309799:DICTH_RS01445
uniprot id: B5YC86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

309799:DICTH RS04400
gene id: 309799:DICTH_RS04400
uniprot id: B5YE18
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm

309799:DICTH RS03705
gene id: 309799:DICTH_RS03705
uniprot id: B5YDN1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

309799:DICTH RS01995
gene id: 309799:DICTH_RS01995
uniprot id: B5YCQ1
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

309799:DICTH RS04950
gene id: 309799:DICTH_RS04950
uniprot id: B5YEB6
names: Similarity
messages: Belongs to the BMP lipoprotein family.

309799:DICTH RS00195
gene id: 309799:DICTH_RS00195
uniprot id: B5YAV1
names: Subcellular Location Annotation
messages: Membrane

309799:DICTH RS05485
gene id: 309799:DICTH_RS05485
uniprot id: B5YEL6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell inner membrane

309799:DICTH RS03820
gene id: 309799:DICTH_RS03820
uniprot id: B5YDQ4
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

309799:DICTH RS08955
gene id: 309799:DICTH_RS08955
uniprot id: B5YBP3
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.
messages: Monomer.

309799:DICTH RS06440
gene id: 309799:DICTH_RS06440
uniprot id: B5YF46
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

309799:DICTH RS04650
gene id: 309799:DICTH_RS04650
uniprot id: B5YE56
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

309799:DICTH RS08205
gene id: 309799:DICTH_RS08205
uniprot id: B5YAN4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycosyl hydrolase 2 family.
messages: Exoglycosidase that cleaves the single beta-linked mannose residue from the non-reducing end of all N-linked glycoprotein oligosaccharides.
messages: Homodimer.
messages: Monomer.
messages: Secreted

309799:DICTH RS04085
gene id: 309799:DICTH_RS04085
uniprot id: B5YDV6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

309799:DICTH RS01285
gene id: 309799:DICTH_RS01285
uniprot id: B5YC50
names: Cofactor
names: Similarity
messages: Belongs to the glycosyl hydrolase 4 family.
messages: Binds 1 NAD(+) per subunit.

309799:DICTH RS00410
gene id: 309799:DICTH_RS00410
uniprot id: B5YAZ5
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

309799:DICTH RS00825
gene id: 309799:DICTH_RS00825
uniprot id: B5YBI5
names: Similarity
messages: Belongs to the glutamate synthase family.

309799:DICTH RS02385
gene id: 309799:DICTH_RS02385
uniprot id: B5YCX9
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

309799:DICTH RS07215
gene id: 309799:DICTH_RS07215
uniprot id: B5YFK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

309799:DICTH RS03490
gene id: 309799:DICTH_RS03490
uniprot id: B5YDJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

309799:DICTH RS03260
gene id: 309799:DICTH_RS03260
uniprot id: B5YDE6
names: Subcellular Location Annotation
messages: Membrane

309799:DICTH RS05955
gene id: 309799:DICTH_RS05955
uniprot id: B5YEV7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

309799:DICTH RS06850
gene id: 309799:DICTH_RS06850
uniprot id: B5YFD0
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

309799:DICTH RS00215
gene id: 309799:DICTH_RS00215
uniprot id: B5YAV5
names: Subcellular Location Annotation
messages: Membrane

309799:DICTH RS07465
gene id: 309799:DICTH_RS07465
uniprot id: B5YA91
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Phosphotriesterase family.
messages: Binds 2 divalent metal cations per subunit.

309799:DICTH RS06020
gene id: 309799:DICTH_RS06020
uniprot id: B5YEX0
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

309799:DICTH RS06030
gene id: 309799:DICTH_RS06030
uniprot id: B5YEX2
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

309799:DICTH RS02640
gene id: 309799:DICTH_RS02640
uniprot id: B5YD30
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

309799:DICTH RS06690
gene id: 309799:DICTH_RS06690
uniprot id: B5YF98
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

309799:DICTH RS08185
gene id: 309799:DICTH_RS08185
uniprot id: B5YAN1
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

309799:DICTH RS04370
gene id: 309799:DICTH_RS04370
uniprot id: B5YE12
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSP33 family.
messages: Cytoplasm
messages: Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.
messages: Under oxidizing conditions two disulfide bonds are formed involving the reactive cysteines. Under reducing conditions zinc is bound to the reactive cysteines and the protein is inactive.

309799:DICTH RS02605
gene id: 309799:DICTH_RS02605
uniprot id: B5YD23
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. MalFG subfamily.
messages: Cell membrane
messages: Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Probably responsible for the translocation of the substrate across the membrane.

309799:DICTH RS01540
gene id: 309799:DICTH_RS01540
uniprot id: B5YCF6
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

309799:DICTH RS00375
gene id: 309799:DICTH_RS00375
uniprot id: B5YAY8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell inner membrane
messages: Probably interacts with PlsX.

309799:DICTH RS03995
gene id: 309799:DICTH_RS03995
uniprot id: B5YDT8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

309799:DICTH RS04900
gene id: 309799:DICTH_RS04900
uniprot id: B5YEA6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

309799:DICTH RS09625
gene id: 309799:DICTH_RS09625
uniprot id: B5YCD7
names: Subcellular Location Annotation
messages: Membrane

309799:DICTH RS04575
gene id: 309799:DICTH_RS04575
uniprot id: B5YE49
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

309799:DICTH RS06880
gene id: 309799:DICTH_RS06880
uniprot id: B5YFD6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

309799:DICTH RS06925
gene id: 309799:DICTH_RS06925
uniprot id: B5YFE5
names: Similarity
messages: Belongs to the LarC family.

309799:DICTH RS10055
gene id: 309799:DICTH_RS10055
uniprot id: B5YD36
names: Subcellular Location Annotation
messages: Membrane

309799:DICTH RS02365
gene id: 309799:DICTH_RS02365
uniprot id: B5YCX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

309799:DICTH RS01595
gene id: 309799:DICTH_RS01595
uniprot id: B5YCG9
names: Similarity
messages: Belongs to the threonine aldolase family.

309799:DICTH RS03270
gene id: 309799:DICTH_RS03270
uniprot id: B5YDE8
names: Activity Regulation
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.

309799:DICTH RS04395
gene id: 309799:DICTH_RS04395
uniprot id: B5YE17
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reduced FMN (FMNH(2)).

309799:DICTH RS04820
gene id: 309799:DICTH_RS04820
uniprot id: B5YE90
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

309799:DICTH RS08510
gene id: 309799:DICTH_RS08510
uniprot id: B5YB43
names: Cofactor
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.

309799:DICTH RS07080
gene id: 309799:DICTH_RS07080
uniprot id: B5YFH7
names: Function
names: Similarity
messages: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
messages: Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines.

309799:DICTH RS06750
gene id: 309799:DICTH_RS06750
uniprot id: B5YFB0
names: Similarity
messages: Belongs to the MEMO1 family.

309799:DICTH RS05170
gene id: 309799:DICTH_RS05170
uniprot id: B5YEF9
names: Similarity
messages: Belongs to the GHMP kinase family. GalK subfamily.

309799:DICTH RS00015
gene id: 309799:DICTH_RS00015
uniprot id: B5YAR5
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class II subfamily.
messages: Catalyzes the reversible conversion of 5-aminoimidazole ribonucleotide (AIR) and CO(2) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

309799:DICTH RS05150
gene id: 309799:DICTH_RS05150
uniprot id: B5YEF5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

309799:DICTH RS03030
gene id: 309799:DICTH_RS03030
uniprot id: P14898
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Cytoplasm
messages: Monomer.
messages: When compared to AmyA, AmyB produced larger amounts of reducing sugar.

309799:DICTH RS04790
gene id: 309799:DICTH_RS04790
uniprot id: B5YE84
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Lacks the C-terminal regulatory region which is replaced by HisZ.

309799:DICTH RS09000
gene id: 309799:DICTH_RS09000
uniprot id: B5YBQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase C chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.

309799:DICTH RS04635
gene id: 309799:DICTH_RS04635
uniprot id: B5YE53
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

309799:DICTH RS03480
gene id: 309799:DICTH_RS03480
uniprot id: B5YDI9
names: Similarity
messages: Belongs to the UPF0758 family.

309799:DICTH RS06610
gene id: 309799:DICTH_RS06610
uniprot id: B5YF82
names: Similarity
messages: Belongs to the ATP:guanido phosphotransferase family.

309799:DICTH RS01945
gene id: 309799:DICTH_RS01945
uniprot id: B5YCP1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell inner membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

309799:DICTH RS04530
gene id: 309799:DICTH_RS04530
uniprot id: B5YE40
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

309799:DICTH RS00675
gene id: 309799:DICTH_RS00675
uniprot id: B5YBF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

309799:DICTH RS00900
gene id: 309799:DICTH_RS00900
uniprot id: B5YBK2
names: Similarity
messages: Belongs to the CRISPR-associated Csm4 family.

309799:DICTH RS04660
gene id: 309799:DICTH_RS04660
uniprot id: B5YE58
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

309799:DICTH RS09175
gene id: 309799:DICTH_RS09175
uniprot id: B5YBT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

309799:DICTH RS03850
gene id: 309799:DICTH_RS03850
uniprot id: B5YDR0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell inner membrane

309799:DICTH RS02395
gene id: 309799:DICTH_RS02395
uniprot id: B5YCY1
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

309799:DICTH RS06590
gene id: 309799:DICTH_RS06590
uniprot id: B5YF78
names: Similarity
messages: Belongs to the ycf81 family.

309799:DICTH RS03620
gene id: 309799:DICTH_RS03620
uniprot id: B5YDL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

309799:DICTH RS06310
gene id: 309799:DICTH_RS06310
uniprot id: B5YF20
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

309799:DICTH RS00735
gene id: 309799:DICTH_RS00735
uniprot id: B5YBG6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

309799:DICTH RS01415
gene id: 309799:DICTH_RS01415
uniprot id: B5YC80
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

309799:DICTH RS04075
gene id: 309799:DICTH_RS04075
uniprot id: B5YDV4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

309799:DICTH RS09040
gene id: 309799:DICTH_RS09040
uniprot id: B5YBR0
names: Similarity
messages: Belongs to the IMPACT family.

309799:DICTH RS04720
gene id: 309799:DICTH_RS04720
uniprot id: B5YE70
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

309799:DICTH RS09375
gene id: 309799:DICTH_RS09375
uniprot id: B5YBX9
names: Similarity
messages: Belongs to the ParB family.

309799:DICTH RS07570
gene id: 309799:DICTH_RS07570
uniprot id: P14899
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Cytoplasm
messages: Monomer.
messages: The profile of production of reducing sugar from soluble starch by the action of AmyC was intermediate between those of AmyA and AmyB.

309799:DICTH RS05145
gene id: 309799:DICTH_RS05145
uniprot id: B5YEF4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homotetramer.

309799:DICTH RS04100
gene id: 309799:DICTH_RS04100
uniprot id: B5YDV9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

309799:DICTH RS05380
gene id: 309799:DICTH_RS05380
uniprot id: B5YEJ5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

309799:DICTH RS04380
gene id: 309799:DICTH_RS04380
uniprot id: B5YE14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

309799:DICTH RS01625
gene id: 309799:DICTH_RS01625
uniprot id: B5YCH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

309799:DICTH RS00055
gene id: 309799:DICTH_RS00055
uniprot id: B5YAS3
names: Similarity
messages: Belongs to the glycosyl hydrolase 26 family.

309799:DICTH RS07260
gene id: 309799:DICTH_RS07260
uniprot id: B5YFL3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RuvC family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.

309799:DICTH RS00315
gene id: 309799:DICTH_RS00315
uniprot id: B5YAX6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

309799:DICTH RS06555
gene id: 309799:DICTH_RS06555
uniprot id: B5YF71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Cell membrane
messages: Membrane

309799:DICTH RS05230
gene id: 309799:DICTH_RS05230
uniprot id: B5YEH2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

309799:DICTH RS07405
gene id: 309799:DICTH_RS07405
uniprot id: B5YA79
names: Subcellular Location Annotation
messages: Membrane

309799:DICTH RS03615
gene id: 309799:DICTH_RS03615
uniprot id: B5YDL3
names: Cofactor
names: Similarity
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.

309799:DICTH RS06450
gene id: 309799:DICTH_RS06450
uniprot id: B5YF48
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

309799:DICTH RS02600
gene id: 309799:DICTH_RS02600
uniprot id: B5YD22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

309799:DICTH RS09445
gene id: 309799:DICTH_RS09445
uniprot id: B5YCA0
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

309799:DICTH RS08615
gene id: 309799:DICTH_RS08615
uniprot id: B5YB64
names: Cofactor
messages: Binds 1 zinc ion per subunit.

309799:DICTH RS06665
gene id: 309799:DICTH_RS06665
uniprot id: B5YF93
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

309799:DICTH RS04965
gene id: 309799:DICTH_RS04965
uniprot id: B5YEB9
names: Subcellular Location Annotation
messages: Membrane

309799:DICTH RS07140
gene id: 309799:DICTH_RS07140
uniprot id: B5YFJ1
names: Subcellular Location Annotation
messages: Membrane

309799:DICTH RS03900
gene id: 309799:DICTH_RS03900
uniprot id: B5YDR9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

309799:DICTH RS04060
gene id: 309799:DICTH_RS04060
uniprot id: B5YDV1
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

309799:DICTH RS01835
gene id: 309799:DICTH_RS01835
uniprot id: B5YCL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

309799:DICTH RS01730
gene id: 309799:DICTH_RS01730
uniprot id: B5YCJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

309799:DICTH RS05465
gene id: 309799:DICTH_RS05465
uniprot id: B5YEL2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

309799:DICTH RS06950
gene id: 309799:DICTH_RS06950
uniprot id: B5YFF1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

309799:DICTH RS06495
gene id: 309799:DICTH_RS06495
uniprot id: B5YF58
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

309799:DICTH RS06705
gene id: 309799:DICTH_RS06705
uniprot id: B5YFA1
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit.

309799:DICTH RS09610
gene id: 309799:DICTH_RS09610
uniprot id: B5YCD4
names: Similarity
messages: Belongs to the AP endonuclease 2 family.

309799:DICTH RS03400
gene id: 309799:DICTH_RS03400
uniprot id: B5YDH5
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

309799:DICTH RS09570
gene id: 309799:DICTH_RS09570
uniprot id: B5YCC6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

309799:DICTH RS01740
gene id: 309799:DICTH_RS01740
uniprot id: B5YCK0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

309799:DICTH RS05965
gene id: 309799:DICTH_RS05965
uniprot id: B5YEV9
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

309799:DICTH RS08145
gene id: 309799:DICTH_RS08145
uniprot id: B5YAM3
names: Subcellular Location Annotation
messages: Membrane

309799:DICTH RS04200
gene id: 309799:DICTH_RS04200
uniprot id: B5YDX9
names: Cofactor
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

309799:DICTH RS06065
gene id: 309799:DICTH_RS06065
uniprot id: B5YEX9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

309799:DICTH RS09115
gene id: 309799:DICTH_RS09115
uniprot id: B5YBS5
names: Cofactor
names: Similarity
messages: Belongs to the glycosyl hydrolase 4 family.
messages: Binds 1 NAD(+) per subunit.

309799:DICTH RS05655
gene id: 309799:DICTH_RS05655
uniprot id: B5YEQ2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

309799:DICTH RS04095
gene id: 309799:DICTH_RS04095
uniprot id: B5YDV8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

309799:DICTH RS02920
gene id: 309799:DICTH_RS02920
uniprot id: B5YD85
names: Similarity
messages: Belongs to the peptidase U62 family.

309799:DICTH RS02980
gene id: 309799:DICTH_RS02980
uniprot id: B5YD92
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

309799:DICTH RS04960
gene id: 309799:DICTH_RS04960
uniprot id: B5YEB8
names: Subcellular Location Annotation
messages: Membrane

309799:DICTH RS08515
gene id: 309799:DICTH_RS08515
uniprot id: B5YB44
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 2 family.

309799:DICTH RS05490
gene id: 309799:DICTH_RS05490
uniprot id: B5YEL7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

309799:DICTH RS06145
gene id: 309799:DICTH_RS06145
uniprot id: B5YEZ0
names: Subcellular Location Annotation
messages: Membrane

309799:DICTH RS07940
gene id: 309799:DICTH_RS07940
uniprot id: B5YAI3
names: Subcellular Location Annotation
messages: Membrane

309799:DICTH RS03815
gene id: 309799:DICTH_RS03815
uniprot id: B5YDQ3
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

309799:DICTH RS04080
gene id: 309799:DICTH_RS04080
uniprot id: B5YDV5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

309799:DICTH RS04210
gene id: 309799:DICTH_RS04210
uniprot id: B5YDY1
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

309799:DICTH RS06475
gene id: 309799:DICTH_RS06475
uniprot id: B5YF54
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

309799:DICTH RS04175
gene id: 309799:DICTH_RS04175
uniprot id: B5YDX4
names: Subcellular Location Annotation
messages: Membrane

309799:DICTH RS07615
gene id: 309799:DICTH_RS07615
uniprot id: B5YAC1
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

309799:DICTH RS06350
gene id: 309799:DICTH_RS06350
uniprot id: B5YF28
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

309799:DICTH RS05975
gene id: 309799:DICTH_RS05975
uniprot id: B5YEW1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

309799:DICTH RS08645
gene id: 309799:DICTH_RS08645
uniprot id: B5YB70
names: Similarity
messages: Belongs to the peptidase A31 family.

309799:DICTH RS04880
gene id: 309799:DICTH_RS04880
uniprot id: B5YEA2
names: Similarity
messages: Belongs to the asp23 family.

309799:DICTH RS01775
gene id: 309799:DICTH_RS01775
uniprot id: B5YCK7
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

309799:DICTH RS04310
gene id: 309799:DICTH_RS04310
uniprot id: B5YE00
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

309799:DICTH RS06960
gene id: 309799:DICTH_RS06960
uniprot id: B5YFF3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

309799:DICTH RS07200
gene id: 309799:DICTH_RS07200
uniprot id: B5YFK1
names: Similarity
messages: Belongs to the RecJ family.

309799:DICTH RS05030
gene id: 309799:DICTH_RS05030
uniprot id: B5YED1
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

309799:DICTH RS08040
gene id: 309799:DICTH_RS08040
uniprot id: B5YAK2
names: Similarity
messages: In the N-terminal section; belongs to the zinc metallo-hydrolase group 3 family.

309799:DICTH RS02445
gene id: 309799:DICTH_RS02445
uniprot id: B5YCZ1
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

309799:DICTH RS08140
gene id: 309799:DICTH_RS08140
uniprot id: B5YAM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

309799:DICTH RS05275
gene id: 309799:DICTH_RS05275
uniprot id: B5YEI1
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

309799:DICTH RS00800
gene id: 309799:DICTH_RS00800
uniprot id: B5YBI0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated exonuclease Cas4 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).
messages: Mg(2+) or Mn(2+) required for ssDNA cleavage activity.

309799:DICTH RS05435
gene id: 309799:DICTH_RS05435
uniprot id: B5YEK6
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

309799:DICTH RS03230
gene id: 309799:DICTH_RS03230
uniprot id: B5YDE1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

309799:DICTH RS09575
gene id: 309799:DICTH_RS09575
uniprot id: B5YCC7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

309799:DICTH RS05650
gene id: 309799:DICTH_RS05650
uniprot id: B5YEQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

309799:DICTH RS04375
gene id: 309799:DICTH_RS04375
uniprot id: B5YE13
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

309799:DICTH RS07935
gene id: 309799:DICTH_RS07935
uniprot id: B5YAI2
names: Cofactor
names: Similarity
messages: Belongs to the glycosyl hydrolase 4 family.
messages: Binds 1 NAD(+) per subunit.

309799:DICTH RS05165
gene id: 309799:DICTH_RS05165
uniprot id: B5YEF8
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

309799:DICTH RS04520
gene id: 309799:DICTH_RS04520
uniprot id: B5YE38
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

309799:DICTH RS00450
gene id: 309799:DICTH_RS00450
uniprot id: B5YB01
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

309799:DICTH RS09405
gene id: 309799:DICTH_RS09405
uniprot id: B5YC92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

309799:DICTH RS03410
gene id: 309799:DICTH_RS03410
uniprot id: B5YDH7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

309799:DICTH RS04050
gene id: 309799:DICTH_RS04050
uniprot id: B5YDU9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

309799:DICTH RS01990
gene id: 309799:DICTH_RS01990
uniprot id: B5YCQ0
names: Similarity
messages: Belongs to the polysaccharide synthase family.

309799:DICTH RS03865
gene id: 309799:DICTH_RS03865
uniprot id: B5YDR3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

309799:DICTH RS00670
gene id: 309799:DICTH_RS00670
uniprot id: B5YBF4
names: Similarity
messages: Belongs to the glycosyl hydrolase 63 family.

309799:DICTH RS02865
gene id: 309799:DICTH_RS02865
uniprot id: B5YD74
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the flotillin-like FloA family.
messages: Cell membrane
messages: Found in functional membrane microdomains (FMM) that may be equivalent to eukaryotic membrane rafts. FMMs are highly dynamic and increase in number as cells age. Flotillins are thought to be important factors in membrane fluidity.
messages: Homooligomerizes.
messages: Membrane raft

309799:DICTH RS06335
gene id: 309799:DICTH_RS06335
uniprot id: B5YF25
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

309799:DICTH RS06375
gene id: 309799:DICTH_RS06375
uniprot id: B5YF33
names: Similarity
messages: Belongs to the phosphohexose mutase family.

309799:DICTH RS07810
gene id: 309799:DICTH_RS07810
uniprot id: B5YAF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

309799:DICTH RS06150
gene id: 309799:DICTH_RS06150
uniprot id: B5YEZ1
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
messages: Cytoplasm
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Non-allosteric.

309799:DICTH RS00290
gene id: 309799:DICTH_RS00290
uniprot id: B5YAX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

309799:DICTH RS02125
gene id: 309799:DICTH_RS02125
uniprot id: B5YCS7
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

309799:DICTH RS05160
gene id: 309799:DICTH_RS05160
uniprot id: B5YEF7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

309799:DICTH RS03355
gene id: 309799:DICTH_RS03355
uniprot id: B5YDG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

309799:DICTH RS05735
gene id: 309799:DICTH_RS05735
uniprot id: B5YER3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
messages: Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
messages: Homodimer.

309799:DICTH RS06630
gene id: 309799:DICTH_RS06630
uniprot id: B5YF86
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

309799:DICTH RS09525
gene id: 309799:DICTH_RS09525
uniprot id: B5YCB7
names: Similarity
messages: Belongs to the tRNA methyltransferase O family.

309799:DICTH RS02340
gene id: 309799:DICTH_RS02340
uniprot id: B5YCX0
names: Subcellular Location Annotation
messages: Membrane

309799:DICTH RS00205
gene id: 309799:DICTH_RS00205
uniprot id: B5YAV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

309799:DICTH RS04835
gene id: 309799:DICTH_RS04835
uniprot id: B5YE93
names: Function
names: Similarity
messages: Belongs to the RapZ-like family.
messages: Displays ATPase and GTPase activities.

309799:DICTH RS03795
gene id: 309799:DICTH_RS03795
uniprot id: B5YDP9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

309799:DICTH RS03075
gene id: 309799:DICTH_RS03075
uniprot id: B5YDB0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.

309799:DICTH RS09220
gene id: 309799:DICTH_RS09220
uniprot id: B5YBU7
names: Similarity
messages: Belongs to the glutamine synthetase family.

309799:DICTH RS04125
gene id: 309799:DICTH_RS04125
uniprot id: B5YDW4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

309799:DICTH RS04735
gene id: 309799:DICTH_RS04735
uniprot id: B5YE73
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

309799:DICTH RS04130
gene id: 309799:DICTH_RS04130
uniprot id: B5YDW5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

309799:DICTH RS08100
gene id: 309799:DICTH_RS08100
uniprot id: B5YAL4
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

309799:DICTH RS04090
gene id: 309799:DICTH_RS04090
uniprot id: B5YDV7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

309799:DICTH RS08935
gene id: 309799:DICTH_RS08935
uniprot id: B5YBN9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

309799:DICTH RS03765
gene id: 309799:DICTH_RS03765
uniprot id: B5YDP3
names: Subcellular Location Annotation
messages: Membrane

309799:DICTH RS07220
gene id: 309799:DICTH_RS07220
uniprot id: B5YFK5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

309799:DICTH RS06210
gene id: 309799:DICTH_RS06210
uniprot id: B5YF02
names: Similarity
messages: Belongs to the acylphosphatase family.

309799:DICTH RS00210
gene id: 309799:DICTH_RS00210
uniprot id: B5YAV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

309799:DICTH RS03450
gene id: 309799:DICTH_RS03450
uniprot id: B5YDI3
names: Similarity
messages: Belongs to the GSP E family.

309799:DICTH RS06895
gene id: 309799:DICTH_RS06895
uniprot id: B5YFD9
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

309799:DICTH RS03755
gene id: 309799:DICTH_RS03755
uniprot id: B5YDP1
names: Similarity
messages: Belongs to the leucine-binding protein family.

309799:DICTH RS06710
gene id: 309799:DICTH_RS06710
uniprot id: B5YFA2
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit.

309799:DICTH RS06195
gene id: 309799:DICTH_RS06195
uniprot id: B5YEZ9
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.

309799:DICTH RS06175
gene id: 309799:DICTH_RS06175
uniprot id: B5YEZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

309799:DICTH RS04250
gene id: 309799:DICTH_RS04250
uniprot id: B5YDY8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Plays an essential role in type IV pili and type II pseudopili formation by proteolytically removing the leader sequence from substrate proteins and subsequently monomethylating the alpha-amino group of the newly exposed N-terminal phenylalanine.

309799:DICTH RS06525
gene id: 309799:DICTH_RS06525
uniprot id: B5YF65
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
messages: Cytoplasm

309799:DICTH RS09260
gene id: 309799:DICTH_RS09260
uniprot id: B5YBV5
names: Similarity
messages: Belongs to the peptidase U62 family.

309799:DICTH RS03280
gene id: 309799:DICTH_RS03280
uniprot id: B5YDF0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

309799:DICTH RS03255
gene id: 309799:DICTH_RS03255
uniprot id: B5YDE5
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

309799:DICTH RS04140
gene id: 309799:DICTH_RS04140
uniprot id: B5YDW7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

309799:DICTH RS06520
gene id: 309799:DICTH_RS06520
uniprot id: B5YF64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

309799:DICTH RS02175
gene id: 309799:DICTH_RS02175
uniprot id: B5YCT7
names: Similarity
messages: Belongs to the creatininase superfamily.

309799:DICTH RS09070
gene id: 309799:DICTH_RS09070
uniprot id: B5YBR6
names: Subcellular Location Annotation
messages: Membrane

309799:DICTH RS04120
gene id: 309799:DICTH_RS04120
uniprot id: B5YDW3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Monomer.

309799:DICTH RS06395
gene id: 309799:DICTH_RS06395
uniprot id: B5YF37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

309799:DICTH RS04230
gene id: 309799:DICTH_RS04230
uniprot id: B5YDY5
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

309799:DICTH RS07380
gene id: 309799:DICTH_RS07380
uniprot id: B5YA75
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

309799:DICTH RS05450
gene id: 309799:DICTH_RS05450
uniprot id: B5YEK9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell inner membrane
messages: Self-interacts. Interacts with FtsZ.

309799:DICTH RS09190
gene id: 309799:DICTH_RS09190
uniprot id: B5YBU0
names: Similarity
messages: Belongs to the glycosyl hydrolase 28 family.

309799:DICTH RS03045
gene id: 309799:DICTH_RS03045
uniprot id: B5YDA4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

309799:DICTH RS08005
gene id: 309799:DICTH_RS08005
uniprot id: B5YAJ5
names: Subcellular Location Annotation
messages: Membrane

309799:DICTH RS02870
gene id: 309799:DICTH_RS02870
uniprot id: B5YD75
names: Subcellular Location Annotation
messages: Membrane

309799:DICTH RS04975
gene id: 309799:DICTH_RS04975
uniprot id: B5YEC1
names: Domain
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

309799:DICTH RS07325
gene id: 309799:DICTH_RS07325
uniprot id: B5YA64
names: Similarity
messages: Belongs to the UDPGP type 2 family.

309799:DICTH RS08030
gene id: 309799:DICTH_RS08030
uniprot id: B5YAK0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the transcriptional regulatory CopG/NikR family.
messages: Binds 1 nickel ion per subunit.
messages: Transcriptional regulator.

309799:DICTH RS07805
gene id: 309799:DICTH_RS07805
uniprot id: B5YAF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

309799:DICTH RS00485
gene id: 309799:DICTH_RS00485
uniprot id: B5YB08
names: Similarity
messages: Belongs to the XFP family.

309799:DICTH RS01430
gene id: 309799:DICTH_RS01430
uniprot id: B5YC83
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

309799:DICTH RS00775
gene id: 309799:DICTH_RS00775
uniprot id: B5YBH5
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated protein Cas6/Cse3/CasE family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).

309799:DICTH RS03740
gene id: 309799:DICTH_RS03740
uniprot id: B5YDN8
names: Function
names: Similarity
messages: Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).

309799:DICTH RS04545
gene id: 309799:DICTH_RS04545
uniprot id: B5YE43
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Monomer.

309799:DICTH RS03745
gene id: 309799:DICTH_RS03745
uniprot id: B5YDN9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L-homocysteine, respectively. Is also able to deaminate adenosine.

309799:DICTH RS01790
gene id: 309799:DICTH_RS01790
uniprot id: B5YCL0
names: Similarity
messages: Belongs to the DsrF/TusC family.

309799:DICTH RS02780
gene id: 309799:DICTH_RS02780
uniprot id: B5YD59
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

309799:DICTH RS03920
gene id: 309799:DICTH_RS03920
uniprot id: B5YDS3
names: Subcellular Location Annotation
messages: Membrane

309799:DICTH RS04665
gene id: 309799:DICTH_RS04665
uniprot id: B5YE59
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

309799:DICTH RS00895
gene id: 309799:DICTH_RS00895
uniprot id: B5YBK1
names: Similarity
messages: Belongs to the CRISPR-associated Csm3 family.

309799:DICTH RS04365
gene id: 309799:DICTH_RS04365
uniprot id: B5YE11
names: Cofactor
names: Similarity
messages: Belongs to the AlaDH/PNT family.
messages: Binds 1 Mg(2+) ion per subunit.

309799:DICTH RS05880
gene id: 309799:DICTH_RS05880
uniprot id: B5YEU2
names: Similarity
messages: Belongs to the RutC family.

309799:DICTH RS05785
gene id: 309799:DICTH_RS05785
uniprot id: B5YES3
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.

309799:DICTH RS08625
gene id: 309799:DICTH_RS08625
uniprot id: B5YB66
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

309799:DICTH RS06090
gene id: 309799:DICTH_RS06090
uniprot id: B5YEY3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

309799:DICTH RS04565
gene id: 309799:DICTH_RS04565
uniprot id: B5YE47
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

309799:DICTH RS08430
gene id: 309799:DICTH_RS08430
uniprot id: B5YB27
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

309799:DICTH RS08875
gene id: 309799:DICTH_RS08875
uniprot id: B5YBM7
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

309799:DICTH RS04435
gene id: 309799:DICTH_RS04435
uniprot id: B5YE25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

309799:DICTH RS06330
gene id: 309799:DICTH_RS06330
uniprot id: B5YF24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

309799:DICTH RS05185
gene id: 309799:DICTH_RS05185
uniprot id: B5YEG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

309799:DICTH RS04055
gene id: 309799:DICTH_RS04055
uniprot id: B5YDV0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

309799:DICTH RS03785
gene id: 309799:DICTH_RS03785
uniprot id: B5YDP7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

309799:DICTH RS03855
gene id: 309799:DICTH_RS03855
uniprot id: B5YDR1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

309799:DICTH RS05875
gene id: 309799:DICTH_RS05875
uniprot id: B5YEU1
names: Subcellular Location Annotation
messages: Membrane

309799:DICTH RS08050
gene id: 309799:DICTH_RS08050
uniprot id: B5YAK4
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

309799:DICTH RS04630
gene id: 309799:DICTH_RS04630
uniprot id: B5YE52
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

309799:DICTH RS04795
gene id: 309799:DICTH_RS04795
uniprot id: B5YE85
names: Cofactor
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.

309799:DICTH RS04040
gene id: 309799:DICTH_RS04040
uniprot id: B5YDU7
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

309799:DICTH RS08095
gene id: 309799:DICTH_RS08095
uniprot id: B5YAL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

309799:DICTH RS01950
gene id: 309799:DICTH_RS01950
uniprot id: B5YCP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

309799:DICTH RS07700
gene id: 309799:DICTH_RS07700
uniprot id: B5YAD6
names: Subcellular Location Annotation
messages: Membrane

309799:DICTH RS07730
gene id: 309799:DICTH_RS07730
uniprot id: B5YAE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

309799:DICTH RS02325
gene id: 309799:DICTH_RS02325
uniprot id: B5YCW7
names: Similarity
messages: Belongs to the CapA family.

309799:DICTH RS08900
gene id: 309799:DICTH_RS08900
uniprot id: B5YBN2
names: Subcellular Location Annotation
messages: Membrane

309799:DICTH RS06675
gene id: 309799:DICTH_RS06675
uniprot id: B5YF95
names: Similarity
messages: Belongs to the serine/threonine dehydratase family.

309799:DICTH RS05460
gene id: 309799:DICTH_RS05460
uniprot id: B5YEL1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

309799:DICTH RS04845
gene id: 309799:DICTH_RS04845
uniprot id: B5YE95
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

309799:DICTH RS05180
gene id: 309799:DICTH_RS05180
uniprot id: B5YEG2
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

309799:DICTH RS08690
gene id: 309799:DICTH_RS08690
uniprot id: B5YB80
names: Subcellular Location Annotation
messages: Membrane

309799:DICTH RS02835
gene id: 309799:DICTH_RS02835
uniprot id: B5YD71
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

309799:DICTH RS08125
gene id: 309799:DICTH_RS08125
uniprot id: B5YAL9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.

309799:DICTH RS08595
gene id: 309799:DICTH_RS08595
uniprot id: B5YB60
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably interacts with PlsX.

309799:DICTH RS03525
gene id: 309799:DICTH_RS03525
uniprot id: B5YDJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

309799:DICTH RS01910
gene id: 309799:DICTH_RS01910
uniprot id: B5YCN4
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

309799:DICTH RS06775
gene id: 309799:DICTH_RS06775
uniprot id: B5YFB5
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

309799:DICTH RS05405
gene id: 309799:DICTH_RS05405
uniprot id: B5YEK0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. MrdB/RodA subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell wall elongation.

309799:DICTH RS00105
gene id: 309799:DICTH_RS00105
uniprot id: B5YAT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

309799:DICTH RS05645
gene id: 309799:DICTH_RS05645
uniprot id: B5YEQ0
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

309799:DICTH RS06460
gene id: 309799:DICTH_RS06460
uniprot id: B5YF50
names: Similarity
messages: Belongs to the RemA family.

309799:DICTH RS06295
gene id: 309799:DICTH_RS06295
uniprot id: B5YF17
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

309799:DICTH RS06410
gene id: 309799:DICTH_RS06410
uniprot id: B5YF40
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

309799:DICTH RS07895
gene id: 309799:DICTH_RS07895
uniprot id: B5YAH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

309799:DICTH RS07620
gene id: 309799:DICTH_RS07620
uniprot id: B5YAC2
names: Subcellular Location Annotation
messages: Membrane

309799:DICTH RS04160
gene id: 309799:DICTH_RS04160
uniprot id: B5YDX1
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

309799:DICTH RS09440
gene id: 309799:DICTH_RS09440
uniprot id: B5YC99
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

309799:DICTH RS05630
gene id: 309799:DICTH_RS05630
uniprot id: B5YEP7
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

309799:DICTH RS08910
gene id: 309799:DICTH_RS08910
uniprot id: B5YBN4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

309799:DICTH RS00930
gene id: 309799:DICTH_RS00930
uniprot id: B5YBK8
names: Similarity
messages: Belongs to the pyrroline-5-carboxylate reductase family.

309799:DICTH RS06055
gene id: 309799:DICTH_RS06055
uniprot id: B5YEX7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

309799:DICTH RS05885
gene id: 309799:DICTH_RS05885
uniprot id: B5YEU3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

309799:DICTH RS04245
gene id: 309799:DICTH_RS04245
uniprot id: B5YDY7
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

309799:DICTH RS09580
gene id: 309799:DICTH_RS09580
uniprot id: B5YCC8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

309799:DICTH RS06015
gene id: 309799:DICTH_RS06015
uniprot id: B5YEW9
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

309799:DICTH RS06270
gene id: 309799:DICTH_RS06270
uniprot id: B5YF12
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

309799:DICTH RS09250
gene id: 309799:DICTH_RS09250
uniprot id: B5YBV3
names: Similarity
messages: Belongs to the PHP hydrolase family. HisK subfamily.

309799:DICTH RS02635
gene id: 309799:DICTH_RS02635
uniprot id: B5YD29
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SIS family. GmhA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
messages: Cytoplasm
messages: The reaction produces a racemic mixture of D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate.

309799:DICTH RS06560
gene id: 309799:DICTH_RS06560
uniprot id: B5YF72
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Homodimer.

309799:DICTH RS08150
gene id: 309799:DICTH_RS08150
uniprot id: B5YAM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

309799:DICTH RS07495
gene id: 309799:DICTH_RS07495
uniprot id: B5YA97
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).

309799:DICTH RS04675
gene id: 309799:DICTH_RS04675
uniprot id: B5YE61
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ApbE family.
messages: Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.
messages: Magnesium. Can also use manganese.

309799:DICTH RS05475
gene id: 309799:DICTH_RS05475
uniprot id: B5YEL4
names: Subcellular Location Annotation
messages: Membrane

309799:DICTH RS09340
gene id: 309799:DICTH_RS09340
uniprot id: B5YBX1
names: Function
names: Similarity
messages: Belongs to the type-2 OGG1 family.
messages: Catalyzes the excision of an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine = 8-oxoG) from DNA. Also cleaves the DNA backbone at apurinic/apyrimidinic sites (AP sites).

309799:DICTH RS04890
gene id: 309799:DICTH_RS04890
uniprot id: B5YEA4
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

309799:DICTH RS04440
gene id: 309799:DICTH_RS04440
uniprot id: B5YE26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

309799:DICTH RS03040
gene id: 309799:DICTH_RS03040
uniprot id: B5YDA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

309799:DICTH RS04555
gene id: 309799:DICTH_RS04555
uniprot id: B5YE45
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

309799:DICTH RS02855
gene id: 309799:DICTH_RS02855
uniprot id: B5YD73
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

309799:DICTH RS02370
gene id: 309799:DICTH_RS02370
uniprot id: B5YCX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

309799:DICTH RS02065
gene id: 309799:DICTH_RS02065
uniprot id: B5YCR4
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

309799:DICTH RS01645
gene id: 309799:DICTH_RS01645
uniprot id: B5YCI0
names: Subcellular Location Annotation
messages: Membrane

309799:DICTH RS08985
gene id: 309799:DICTH_RS08985
uniprot id: B5YBP9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

309799:DICTH RS06255
gene id: 309799:DICTH_RS06255
uniprot id: B5YF09
names: Similarity
messages: Belongs to the MreC family.

309799:DICTH RS04670
gene id: 309799:DICTH_RS04670
uniprot id: B5YE60
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.
messages: Binds 3 [4Fe-4S] clusters.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

309799:DICTH RS08360
gene id: 309799:DICTH_RS08360
uniprot id: B5YB12
names: Similarity
messages: Belongs to the peptidase S24 family.

309799:DICTH RS03735
gene id: 309799:DICTH_RS03735
uniprot id: B5YDN7
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Although this enzyme belongs to the family of MTA phosphorylases based on sequence homology, it has been shown that conserved amino acid substitutions in the substrate binding pocket convert the substrate specificity of this enzyme from 6-aminopurines to 6-oxopurines.
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Homohexamer. Dimer of a homotrimer.
messages: Purine nucleoside phosphorylase which is highly specific for 6-oxopurine nucleosides. Cleaves guanosine or inosine to respective bases and sugar-1-phosphate molecules. Involved in purine salvage.

309799:DICTH RS05970
gene id: 309799:DICTH_RS05970
uniprot id: B5YEW0
names: Subcellular Location Annotation
messages: Membrane

309799:DICTH RS04855
gene id: 309799:DICTH_RS04855
uniprot id: B5YE97
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

309799:DICTH RS09390
gene id: 309799:DICTH_RS09390
uniprot id: B5YC89
names: Cofactor
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

309799:DICTH RS03950
gene id: 309799:DICTH_RS03950
uniprot id: B5YDS9
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

309799:DICTH RS06810
gene id: 309799:DICTH_RS06810
uniprot id: B5YFC2
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

309799:DICTH RS06205
gene id: 309799:DICTH_RS06205
uniprot id: B5YF01
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

309799:DICTH RS09515
gene id: 309799:DICTH_RS09515
uniprot id: B5YCB5
names: Similarity
messages: Belongs to the glycosyl hydrolase 11 (cellulase G) family.

309799:DICTH RS07430
gene id: 309799:DICTH_RS07430
uniprot id: B5YA84
names: Similarity
messages: Belongs to the glycosyl hydrolase 10 (cellulase F) family.

309799:DICTH RS01980
gene id: 309799:DICTH_RS01980
uniprot id: B5YCP8
names: Subcellular Location Annotation
messages: Membrane

309799:DICTH RS02590
gene id: 309799:DICTH_RS02590
uniprot id: B5YD21
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RNase HII family.
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

309799:DICTH RS04345
gene id: 309799:DICTH_RS04345
uniprot id: B5YE07
names: Similarity
messages: Belongs to the TlyA family.

309799:DICTH RS05620
gene id: 309799:DICTH_RS05620
uniprot id: B5YEP5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Monomer.

309799:DICTH RS06700
gene id: 309799:DICTH_RS06700
uniprot id: B5YFA0
names: Similarity
messages: Belongs to the V-ATPase D subunit family.

309799:DICTH RS05300
gene id: 309799:DICTH_RS05300
uniprot id: B5YEI6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

309799:DICTH RS06095
gene id: 309799:DICTH_RS06095
uniprot id: B5YEY4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

309799:DICTH RS03215
gene id: 309799:DICTH_RS03215
uniprot id: B5YDD8
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

309799:DICTH RS06625
gene id: 309799:DICTH_RS06625
uniprot id: B5YF85
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PdxS/SNZ family.
messages: Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
messages: In the presence of PdxT, forms a dodecamer of heterodimers.

309799:DICTH RS06635
gene id: 309799:DICTH_RS06635
uniprot id: B5YF87
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

309799:DICTH RS04320
gene id: 309799:DICTH_RS04320
uniprot id: B5YE02
names: Similarity
messages: Belongs to the asp23 family.

309799:DICTH RS06200
gene id: 309799:DICTH_RS06200
uniprot id: B5YF00
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
messages: Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.
messages: Cytoplasm

309799:DICTH RS06565
gene id: 309799:DICTH_RS06565
uniprot id: B5YF73
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphopentomutase family.
messages: Binds 1 or 2 manganese ions.
messages: Cytoplasm
messages: Phosphotransfer between the C1 and C5 carbon atoms of pentose.

309799:DICTH RS07595
gene id: 309799:DICTH_RS07595
uniprot id: B5YAB7
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

309799:DICTH RS02545
gene id: 309799:DICTH_RS02545
uniprot id: B5YD12
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

309799:DICTH RS06735
gene id: 309799:DICTH_RS06735
uniprot id: B5YFA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Membrane

309799:DICTH RS04815
gene id: 309799:DICTH_RS04815
uniprot id: B5YE89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

309799:DICTH RS08930
gene id: 309799:DICTH_RS08930
uniprot id: B5YBN8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

309799:DICTH RS08250
gene id: 309799:DICTH_RS08250
uniprot id: B5YAP3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

309799:DICTH RS05265
gene id: 309799:DICTH_RS05265
uniprot id: B5YEH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RibF family.
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

309799:DICTH RS01885
gene id: 309799:DICTH_RS01885
uniprot id: B5YCM9
names: Similarity
messages: Belongs to the peptidase U62 family.

309799:DICTH RS05515
gene id: 309799:DICTH_RS05515
uniprot id: B5YEM2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

309799:DICTH RS06235
gene id: 309799:DICTH_RS06235
uniprot id: B5YF05
names: Function
names: Similarity
messages: ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.
messages: Belongs to the ParA family. MinD subfamily.

309799:DICTH RS04155
gene id: 309799:DICTH_RS04155
uniprot id: B5YDX0
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

309799:DICTH RS07055
gene id: 309799:DICTH_RS07055
uniprot id: B5YFH2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

309799:DICTH RS07150
gene id: 309799:DICTH_RS07150
uniprot id: B5YFJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

309799:DICTH RS06620
gene id: 309799:DICTH_RS06620
uniprot id: B5YF84
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glutaminase PdxT/SNO family.
messages: Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
messages: In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer.

309799:DICTH RS06320
gene id: 309799:DICTH_RS06320
uniprot id: B5YF22
names: Similarity
messages: Belongs to the GARS family.

309799:DICTH RS01380
gene id: 309799:DICTH_RS01380
uniprot id: B5YC73
names: Subcellular Location Annotation
messages: Membrane

309799:DICTH RS03980
gene id: 309799:DICTH_RS03980
uniprot id: B5YDT5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDT1 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

309799:DICTH RS00440
gene id: 309799:DICTH_RS00440
uniprot id: B5YAZ9
names: Subcellular Location Annotation
messages: Membrane

309799:DICTH RS00125
gene id: 309799:DICTH_RS00125
uniprot id: B5YAT7
names: Subcellular Location Annotation
messages: Membrane

309799:DICTH RS01055
gene id: 309799:DICTH_RS01055
uniprot id: B5YBZ3
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.

309799:DICTH RS05775
gene id: 309799:DICTH_RS05775
uniprot id: B5YES1
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

309799:DICTH RS07660
gene id: 309799:DICTH_RS07660
uniprot id: B5YAD0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

309799:DICTH RS06445
gene id: 309799:DICTH_RS06445
uniprot id: B5YF47
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

309799:DICTH RS10115
gene id: 309799:DICTH_RS10115
uniprot id: B5YET3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Membrane